SASAKI Mariko 佐々木真理子

Researcher Number	50722013
Other IDs
Affiliation (Current)	2025: 国立遺伝学研究所, 新分野創造センター, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 国立遺伝学研究所, 新分野創造センター, 准教授 2021 – 2022: 東京大学, 定量生命科学研究所, 講師 2018 – 2021: 東京大学, 定量生命科学研究所, 助教 2015 – 2017: 東京大学, 分子細胞生物学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 43050:Genome biology-related / Genetics/Chromosome dynamics / Biological Sciences Except Principal Investigator Biological Sciences
Keywords	Principal Investigator rDNA / DNA複製阻害 / ゲノム不安定化 / ゲノム安定性 / 複製阻害 / Ctf4 / DNA二重鎖切断 / DNA二本鎖切断 / ゲノム再編成 / 染色体外環状DNA … More / DNAコピー数変化 / 非ゲノム情報 / クロマチン構造 / CAF-1複合体 / 相同組換え / 染色体オーケストレーション / DNA修復 / 複製フォーク … More Except Principal Investigator 組換え / ヒストン修飾 / 遺伝子増幅 / クロマチン構造 / DNAの組換え / DNA複製 / 染色体 / インターメア / 培養細胞 / 出芽酵母 / Sir2 / 組換え修復 / イメージング / ゲノムの不安定性 / DNAの組換え修復 / 複製阻害 / 反復配列 / クロマチン / ゲノムの安定性 / 細胞老化 / リボソームRNA遺伝子 / 非コードDNA Less

Understanding the mechanisms by which organisms respond to the change in the rDNA copy numberPrincipal Investigator
- Principal Investigator
  
  佐々木真理子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  National Institute of Genetics
Understanding the mechanisms by which Ctf4 protein suppresses repair of DNA double-strand breaks by homologous recombinationPrincipal Investigator
- Principal Investigator
  
  Mariko Sasaki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  National Institute of Genetics
  The University of Tokyo
Understanding the mechanisms by which chromatin assembly factors promote the maintenance of genome stability upon inhibition of DNA replicationPrincipal Investigator
- Principal Investigator
  
  佐々木真理子
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
DNA二重鎖切断修復によるゲノム安定性維持機構の4D情報Principal Investigator
- Principal Investigator
  
  佐々木真理子
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Understanding the mechanisms by which a replisome component Ctf4 promotes proper repair of DNA double-strand breaks at arrested replication forksPrincipal Investigator
- Principal Investigator
  
  Sasaki Mariko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  The University of Tokyo
Understanding the mechanisms by which Ctf4 protein promotes proper repair of DSBs formed upon inhibition of rDNA replicationPrincipal Investigator
- Principal Investigator
  
  Sasaki Mariko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  The University of Tokyo
Effect of rDNA instability to chromosome and cellular functions
- Principal Investigator
  
  KOBAYASHI Takehiko
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  National Institute of Genetics

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] The peroxiredoxin Tsa1 extends the lifespan of budding yeast by maintaining the stability of the ribosomal RNA gene cluster2024
- Author(s)
  Ohira Junno、Sasaki Mariko、Kobayashi Takehiko
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2024.03.14.585068
- Open Access
- Data Source
  KAKENHI-PROJECT-20K06597
[Journal Article] The histone chaperone CAF-1 maintains the stability of the ribosomal RNA gene cluster by suppressing end resection of replication-associated DNA double-strand breaks2024
- Author(s)
  Futami Hajime、Sasaki Mariko、Kobayashi Takehiko
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2024.03.12.584701
- Open Access
- Data Source
  KAKENHI-PROJECT-20K06597
[Journal Article] Transcription near arrested DNA replication forks triggers ribosomal DNA copy number changes2023
- Author(s)
  Sasaki Mariko、Kobayashi Takehiko
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2023.12.21.572944
- Open Access
- Data Source
  KAKENHI-PROJECT-20K06597
[Journal Article] Acidic growth conditions stabilize the ribosomal RNA gene cluster and extend lifespan through noncoding transcription repression2023
- Author(s)
  Hasegawa Yo、Ooka Hiroyuki、Wakatsuki Tsuyoshi、Sasaki Mariko、Yamamoto Ayumi、Kobayashi Takehiko
- Journal Title
  
  Genes to Cells
  
  Volume: 29 Issue: 2 Pages: 111-130
- DOI
  10.1111/gtc.13089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06597
[Journal Article] Spt4 promotes cellular senescence by activating non-coding RNA transcription in ribosomal RNA gene clusters2023
- Author(s)
  Masaaki Yokoyama, Mariko Sasaki, Takehiko Kobayashi
- Journal Title
  
  Cell Reports
  
  Volume: 42 Pages: 111944-111944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06597
[Journal Article] Spt4 promotes cellular senescence by activating non-coding RNA transcription in ribosomal RNA gene clusters2023
- Author(s)
  Yokoyama Masaaki、Sasaki Mariko、Kobayashi Takehiko
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 1 Pages: 111944-111944
- DOI
  10.1016/j.celrep.2022.111944
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06597
[Journal Article] Spt4 promotes cellular senescence by activating non-coding RNA transcription in ribosomal RNA gene clusters2023
- Author(s)
  Masaaki Yokoyama, Mariko Sasaki and Takehiko Kobayashi
- Journal Title
  
  Cell Reports
  
  Volume: 42 Pages: 111944-111944
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H05382
[Journal Article] Regulatory processes that maintain or alter ribosomal DNA stability during the repair of programmed DNA double-strand breaks2023
- Author(s)
  Mariko Sasaki and Takehiko Kobayashi
- Journal Title
  
  Genes Genet. Syst.
  
  Volume: 98 Issue: 3 Pages: 103-119
- DOI
  10.1266/ggs.22-00046
- ISSN
  1341-7568, 1880-5779
- Year and Date
  2023-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H05382, KAKENHI-PROJECT-20K06597
[Journal Article] Spt4 drives cellular senescence by activating non-coding RNA transcription in ribosomal RNA gene clusters2022
- Author(s)
  Masaaki Yokoyama, Mariko Sasaki, Takehiko Kobayashi
- Journal Title
  
  bioRxiv
  
  Volume: - Pages: 0-0
- DOI
  10.1101/2022.04.22.488906
- Data Source
  KAKENHI-PUBLICLY-20H05382, KAKENHI-PROJECT-20K06597
[Journal Article] The S-phase Cyclin Clb5 Promotes rDNA Stability by Maintaining Replication Initiation Efficiency in rDNA.2021
- Author(s)
  Mayuko Goto, Mariko Sasaki, and Takehiko Kobayashi
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 5 Issue: 5 Pages: 1-1
- DOI
  10.1128/mcb.00324-20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06597, KAKENHI-PUBLICLY-20H05382, KAKENHI-PROJECT-17H01443, KAKENHI-PROJECT-21H04761
[Journal Article] Gel Electrophoresis Analysis of rDNA Instability in Saccharomyces cerevisiae2021
- Author(s)
  Mariko Sasaki, Takehiko Kobayashi
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2153 Pages: 403-425
- DOI
  10.1007/978-1-0716-0644-5_28
- ISBN
  9781071606438, 9781071606445
- Data Source
  KAKENHI-PUBLICLY-20H05382, KAKENHI-PROJECT-20K06597
[Journal Article] Defects in the NuA4 acetyltransferase complex increase stability of the ribosomal RNA gene and extend replicative lifespan2019
- Author(s)
  Tsuyoshi Wakatsuki, Mariko Sasaki, Takehiko Kobayashi
- Journal Title
  
  Genes Genet. Syst.
  
  Volume: 94 Issue: 5 Pages: 197-206
- DOI
  10.1266/ggs.19-00022
- NAID
  130007760285
- ISSN
  1341-7568, 1880-5779
- Year and Date
  2019-10-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04709, KAKENHI-PROJECT-17H01443
[Journal Article] The CCR4-NOT complex maintains stability and transcription of rRNA genes by repressing antisense transcripts.2019
- Author(s)
  Shun Hosoyamada, Mariko Sasaki, Takehiko Kobayashi
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 40 Issue: 1
- DOI
  10.1128/mcb.00320-19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04709, KAKENHI-PROJECT-17H01443
[Journal Article] レプリソームの構成タンパク質であるCtf4は複製が阻害された際に生じるDNA2本鎖切断の修復に重要である2017
- Author(s)
  佐々木真理子、小林武彦
- Journal Title
  
  First Author'sライフサイエンス新着論文レビュー
  
  Volume: ー
- Data Source
  KAKENHI-PROJECT-15K18581
[Journal Article] Ctf4 Prevents Genome Rearrangements by Suppressing DNA Double-Strand Break Formation and Its End Resection at Arrested Replication Forks2017
- Author(s)
  Sasaki Mariko、Kobayashi Takehiko
- Journal Title
  
  Molecular Cell
  
  Volume: 66 Issue: 4 Pages: 533-545
- DOI
  10.1016/j.molcel.2017.04.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15160, KAKENHI-PROJECT-15K18581, KAKENHI-PROJECT-17H01443
[Journal Article] rDNA stability is supported by many "Buffer genes" -Introduction to the Yeast rDNA Stability Database.2017
- Author(s)
  Kobayashi T, Sasaki M
- Journal Title
  
  FEMS Yeast Res.
  
  Volume: - Issue: 1 Pages: 1-8
- DOI
  10.1093/femsyr/fox001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23114002, KAKENHI-WRAPUP-16H01691, KAKENHI-PROJECT-15K18581, KAKENHI-PROJECT-17K15160, KAKENHI-PROJECT-17H01443
[Journal Article] レプリソームの構成タンパク質であるCtf4は複製が阻害された際に生じるDNA二本鎖切断の修復に重要である2017
- Author(s)
  佐々木真理子、小林武彦
- Journal Title
  
  First Autho's ライフサイエンス新着論文レビュー
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-17K15160
[Journal Article] More than 10% of yeast genes are related to genome stability and influence cellular senescence via rDNA maintenance2016
- Author(s)
  Kimiko Saka, Akihiro Takahashi, Mariko Sasaki and Takehiko Kobayashi
- Journal Title
  
  Nucleic Acids Research
  
  Volume: in press Issue: 9 Pages: 1-11
- DOI
  10.1093/nar/gkw110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18581, KAKENHI-ORGANIZER-23114001, KAKENHI-PLANNED-23114002
[Presentation] Understanding mechanisms underlying extrachromosomal circular DNA using budding yeast2023
- Author(s)
  Mariko Sasaki
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K06597
[Presentation] Nearby transcription activity impacts repair pathway choice of DSBs that are formed in response to replication fork arrest2023
- Author(s)
  Mariko Sasaki
- Organizer
  第96回日本生化学会大会、企画シンポジウム「DNA二重鎖切断損傷に応答するゲノム維持システム」
- Data Source
  KAKENHI-PROJECT-20K06597
[Presentation] Rad27 (FEN-1)による新規の rDNA コピー数制御機構の解析2023
- Author(s)
  佐々木　真理子
- Organizer
  第27回DNA 複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-20K06597
[Presentation] Transcription near arrested DNA replication forks triggers rDNA copy number changes.2023
- Author(s)
  Mariko Sasaki
- Organizer
  The 2023 Cold Spring Harbor Asia Conference on YEAST AND LIFE SCIENCES
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06597
[Presentation] 構造特異的ヌクレアーゼRad27(FEN-1)によるrDNA安定性維持機構の解析2023
- Author(s)
  佐々木　真理子
- Organizer
  日本遺伝学会第95回大会
- Data Source
  KAKENHI-PROJECT-20K06597
[Presentation] Interplay between transcription and DNA double-strand break repair impacts genome stability upon DNA replication fork arrest2022
- Author(s)
  佐々木　真理子
- Organizer
  第45回日本分子生物学会、ワークショップ「ゲノム複製研究の最前線 - Flexibility, Fidelity, Fragility」
- Invited
- Data Source
  KAKENHI-PROJECT-20K06597
[Presentation] DNA複製阻害時のDNA二本鎖切断修復と転写制御機構のインタープレイ2022
- Author(s)
  佐々木　真理子、小林　武彦
- Organizer
  日本遺伝学会第94回大会
- Data Source
  KAKENHI-PROJECT-20K06597
[Presentation] Interplay between transcription and DNA double-strand break repair impacts genome stability upon DNA replication fork arrest2022
- Author(s)
  佐々木真理子
- Organizer
  第45回日本分子生物学会、ワークショップ「ゲノム複製研究の最前線 - Flexibility, Fidelity, Fragility」
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05382
[Presentation] DNA複製阻害時のDNA二本鎖切断修復と転写制御機構のインタープレイ2022
- Author(s)
  佐々木真理子, 小林武彦
- Organizer
  日本遺伝学会第94回大会 2022年9月14日
- Data Source
  KAKENHI-PUBLICLY-20H05382
[Presentation] DNA複製阻害時のDNA二本鎖切断修復とゲノム不安定化2021
- Author(s)
  佐々木真理子、小林武彦
- Organizer
  第26回DNA複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-20K06597
[Presentation] DNA複製阻害時のDNA二本鎖切断修復とゲノム不安定化2021
- Author(s)
  佐々木真理子, 小林武彦
- Organizer
  第26回DNA複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PUBLICLY-20H05382
[Presentation] DNA複製阻害時のDNA二本鎖切断修復と転写制御機構のインタープレイ2021
- Author(s)
  佐々木真理子
- Organizer
  日本遺伝学会第93回大会、企画ワークショップ「ゲノムDNA量の変化から紐解く生物の生存戦略」
- Data Source
  KAKENHI-PUBLICLY-20H05382
[Presentation] DNA複製阻害時のDNA二本鎖切断修復によるrDNAコピー数制御機構の解明2021
- Author(s)
  佐々木真理子
- Organizer
  第44回日本分子生物学会、企画ワークショップ「ゲノムDNA量の変化から紐解く生物の生存戦略」
- Data Source
  KAKENHI-PROJECT-20K06597
[Presentation] S期サイクリンClb5によるゲノム安定性維持機構2021
- Author(s)
  佐々木真理子、後藤真由子、小林武彦
- Organizer
  酵母遺伝学フォーラム第54回研究報告回
- Data Source
  KAKENHI-PROJECT-20K06597
[Presentation] DNA複製阻害時のDNA日本鎖切断修復と転写制御機構のインタープレイ2021
- Author(s)
  佐々木　真理子
- Organizer
  第38回染色体ワークショップ、第19回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-20K06597
[Presentation] DNA複製阻害時のDNA二本鎖切断修復と転写制御機構のインタープレイ2021
- Author(s)
  佐々木真理子
- Organizer
  日本遺伝学会第93回大会、企画ワークショップ「ゲノムDNA量の変化から紐解く生物の生存戦略」
- Data Source
  KAKENHI-PROJECT-20K06597
[Presentation] S期サイクリンClb5によるゲノム安定性維持機構2021
- Author(s)
  佐々木真理子, 後藤真由子, 小林武彦
- Organizer
  酵母遺伝学フォーラム第54回研究報告回
- Data Source
  KAKENHI-PUBLICLY-20H05382
[Presentation] DNA複製阻害時のDNA二本鎖切断修復によるrDNAコピー数制御機構の解明2021
- Author(s)
  佐々木真理子
- Organizer
  第44回日本分子生物学会、企画ワークショップ「ゲノムDNA量の変化から紐解く生物の生存戦略」
- Data Source
  KAKENHI-PUBLICLY-20H05382
[Presentation] Mechanisms that regulate repair of DNA double-strand breaks at arrested replication forks2020
- Author(s)
  Mariko Sasaki
- Organizer
  International Symposium for Female Researchers in Chromatin Biology 2020
- Data Source
  KAKENHI-PROJECT-20K06597
[Presentation] クロマチン構造がDNA複製阻害時のDNA二本鎖切断修復に与える影響2019
- Author(s)
  佐々木　真理子
- Organizer
  第92回日本生化学会大会ワークショップ「クロマチン構造上で起こる反応の生化学」
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04709
[Presentation] 複製阻害時のDNA二本鎖切断修復の制御機構2019
- Author(s)
  佐々木　真理子
- Organizer
  第25回DNA複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PUBLICLY-18H04709
[Presentation] DNA複製阻害時のDNA二本鎖切断修復を制御するメカニズム2019
- Author(s)
  佐々木　真理子
- Organizer
  第42回日本分子生物学会ワークショップ「染色体配列や細胞のダイバーシティに適応した精巧かつ柔軟なゲノム安定性維持機構」
- Data Source
  KAKENHI-PUBLICLY-18H04709
[Presentation] クロマチン構造上で起こるDNA複製阻害時のDNA二本鎖切断修復2019
- Author(s)
  佐々木　真理子
- Organizer
  第37回染色体ワークショップ、第18回核ダイナミクス研究会
- Data Source
  KAKENHI-PUBLICLY-18H04709
[Presentation] DNA複製阻害時のDNA二重鎖切断修復機構の解明2018
- Author(s)
  佐々木　真理子
- Organizer
  第41回日本分子生物学会ワークショップ「進むDNA複製フォークの研究：ゲノム恒常性維持の課題と解決」
- Data Source
  KAKENHI-PUBLICLY-18H04709
[Presentation] A replisome component Ctf4 suppresses end resection of DNA double-strand breaks at arrested replication forks2018
- Author(s)
  佐々木　真理子
- Organizer
  11th 3R + 3C Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04709
[Presentation] DNA複製阻害時のDNA二重鎖切断修復機構の解明2018
- Author(s)
  佐々木　真理子
- Organizer
  第41回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K15160
[Presentation] A replisome component Ctf4 suppresses end resection of DNA double-strand breaks at arrested replication forks2018
- Author(s)
  Mariko Sasaki, Takehiko Kobayashi
- Organizer
  Gordon Research Conference Genomic Instability
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04709
[Presentation] A replisome component Ctf4 suppresses end resection of DNA double-strand breaks at arrested replication forks.2018
- Author(s)
  Mariko Sasaki and Takehiko Kobayashi
- Organizer
  Gordon Research Conference Genomic Instability
- Data Source
  KAKENHI-PROJECT-17K15160
[Presentation] A replisome component Ctf4 suppresses end resection of DNA double-strand breaks at arrested replication forks2018
- Author(s)
  Mariko Sasaki and Takehiko Kobayashi
- Organizer
  11th 3R + 3C Symposium
- Data Source
  KAKENHI-PROJECT-17K15160
[Presentation] DNA複製阻害時のDNA二重鎖切断修復機構の解明2018
- Author(s)
  佐々木　真理子、小林　武彦
- Organizer
  日本遺伝学会第90回大会
- Data Source
  KAKENHI-PROJECT-17K15160
[Presentation] DNA複製阻害時のDNA二重鎖切断修復機構の解明2018
- Author(s)
  佐々木真理子, 小林武彦
- Organizer
  日本遺伝学会第90回大会
- Data Source
  KAKENHI-PUBLICLY-18H04709
[Presentation] DNA複製阻害時のDNA複製阻害時の二重鎖切断修復機構の解明2017
- Author(s)
  佐々木　真理子
- Organizer
  日本遺伝学会第89回大会
- Data Source
  KAKENHI-PROJECT-17K15160
[Presentation] DNA複製阻害時のDNA二重鎖切断修復機構の解明2017
- Author(s)
  佐々木　真理子、小林　武彦
- Organizer
  日本遺伝学会第89回大会
- Data Source
  KAKENHI-PROJECT-15K18581
[Presentation] DNA複製阻害によって生じるDNA二重鎖切断修復機構の解明2016
- Author(s)
  佐々木　真理子
- Organizer
  日本遺伝学会第８８回大会
- Place of Presentation
  日本大学国際関係学部（静岡県三島）
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-15K18581
[Presentation] A replisome component Ctf4 suppresses end resection of DNA double-strand breaks at the arrested forks to prevent chromosome rearrangements.2016
- Author(s)
  Mariko Sasaki
- Organizer
  The 10th 3R International Symposium.
- Place of Presentation
  ホテル一畑（島根県松江市）
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18581
[Presentation] A replisome factor Ctf4 protects replication-associated DNA double-strand breaks from rearrangement-prone homologous recombination.2016
- Author(s)
  Mariko Sasaki
- Organizer
  Mechanisms of Recombination 2016
- Place of Presentation
  アリカンテ（スペイン）
- Year and Date
  2016-05-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18581
[Presentation] Mechanism by which the Saccharomyces cerevisiae Ctf4 protein prevents rDNA hyper-amplification2015
- Author(s)
  Mariko Sasaki
- Organizer
  2015 FASEB Science Research Conferences Genetic Recombination & Genome Rearrangements
- Place of Presentation
  Steamboat Springs, Colorado, USA
- Year and Date
  2015-07-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18581
[Presentation] 出芽酵母Ctf4による複製阻害に伴うDNA二重鎖切断形成及び修復制御2015
- Author(s)
  佐々木　真理子
- Organizer
  第２３回　DNA複製・組換え・修復ワークショップ
- Place of Presentation
  焼津グランドホテル（静岡県焼津市）
- Year and Date
  2015-10-19
- Data Source
  KAKENHI-PROJECT-15K18581

1. KOBAYASHI Takehiko (40270475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. IIDA Tetsushi (60391851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. AKAMATSU Yufuko (50381661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HORIGOME Chihiro (10771206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SAKA Kimiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HAEIWA Haruna

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. UNOZAWA Eri

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TAKAHASHI Akihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. WAKATSUKI Tsuyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUZUKI Yu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SASAKI Mariko 佐々木 真理子

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Understanding the mechanisms by which organisms respond to the change in the rDNA copy numberPrincipal Investigator

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Understanding the mechanisms by which Ctf4 protein suppresses repair of DNA double-strand breaks by homologous recombinationPrincipal Investigator

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Understanding the mechanisms by which chromatin assembly factors promote the maintenance of genome stability upon inhibition of DNA replicationPrincipal Investigator

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DNA二重鎖切断修復によるゲノム安定性維持機構の4D情報Principal Investigator

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Understanding the mechanisms by which a replisome component Ctf4 promotes proper repair of DNA double-strand breaks at arrested replication forksPrincipal Investigator

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Understanding the mechanisms by which Ctf4 protein promotes proper repair of DSBs formed upon inhibition of rDNA replicationPrincipal Investigator

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Effect of rDNA instability to chromosome and cellular functions

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[Journal Article] The peroxiredoxin Tsa1 extends the lifespan of budding yeast by maintaining the stability of the ribosomal RNA gene cluster2024

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[Journal Article] The histone chaperone CAF-1 maintains the stability of the ribosomal RNA gene cluster by suppressing end resection of replication-associated DNA double-strand breaks2024

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[Journal Article] Transcription near arrested DNA replication forks triggers ribosomal DNA copy number changes2023

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[Journal Article] Acidic growth conditions stabilize the ribosomal RNA gene cluster and extend lifespan through noncoding transcription repression2023

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[Journal Article] Spt4 promotes cellular senescence by activating non-coding RNA transcription in ribosomal RNA gene clusters2023

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[Journal Article] Spt4 promotes cellular senescence by activating non-coding RNA transcription in ribosomal RNA gene clusters2023

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[Journal Article] Spt4 promotes cellular senescence by activating non-coding RNA transcription in ribosomal RNA gene clusters2023

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[Journal Article] Regulatory processes that maintain or alter ribosomal DNA stability during the repair of programmed DNA double-strand breaks2023

Author(s)

SASAKI Mariko 佐々木真理子