hayashi mitsuhiro 林光博

… Alternative Names

林光博ハヤシミツヒロ

Hayashi Mitsuhiro 林光博

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Researcher Number	50735628
Other IDs	https://orcid.org/0000-0001-6656-8502
Affiliation (Current)	2025: 医療法人社団あんしん会四谷メディカルキューブ(臨床研究管理部), 乳腺外科, 科長
Affiliation (based on the past Project Information) *help	2021: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 研究員 2018 – 2019: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 研究員 2016: 国立研究開発法人国立がん研究センター, 先端医療開発センター, 研究員 2015: 国立研究開発法人国立がん研究センター, 研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Metabolomics Except Principal Investigator Basic Section 47060:Clinical pharmacy-related
Keywords	Principal Investigator Translational research / Circulating tumor DNA / PDX / Liquid biopsy / Breast cancer / elastography / 脂質代謝 / BMI / 脂質 / Elastography / 腫瘍硬度 / 肥満 / 乳癌 … More Except Principal Investigator … More 薬剤感受性 / 分子標的治療薬 / 個別化医療 / CYLD Less

乳癌PDXモデルを活用した循環腫瘍DNAに関するリバーストランスレーショナル研究Principal Investigator
- Principal Investigator
  
  林光博
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  National Cancer Center Japan
Establishing novel molecular-targeted cancer therapies based on molecular diagnostics focusing on prognostic factor CYLD
- Principal Investigator
  
  Jono Hirofumi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kumamoto University
Associations between obesity, abnormal glucose/lipid metabolism, and clinico-biological factors in patients with breast cancerPrincipal Investigator
- Principal Investigator
  
  Hayashi Mitsuhiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  National Cancer Center Japan

All 2021 2019 2018 2016 2015

All Journal Article Presentation

[Journal Article] Eribulin penetrates brain tumor tissue and prolongs survival of mice harboring intracerebral glioblastoma xenografts2019
- Author(s)
  Takahashi Masamichi、Miki Shunichiro、Fujimoto Kenji、Fukuoka Kohei、Matsushita Yuko、Maida Yoshiko、Yasukawa Mami、Hayashi Mitsuhiro、Shinkyo Raku、Kikuchi Kiyomi、Mukasa Akitake、Nishikawa Ryo、Tamura Kenji、Narita Yoshitaka、Hamada Akinobu、Masutomi Kenkichi、Ichimura Koichi
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 7 Pages: 2247-2257
- DOI
  10.1111/cas.14067
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10777, KAKENHI-PROJECT-18K16132, KAKENHI-PROJECT-17H04300
[Journal Article] Applications of MALDI mass spectrometry imaging for pharmacokinetic studies during drug development2019
- Author(s)
  Nishidate Masanobu、Hayashi Mitsuhiro、Aikawa Hiroaki、Tanaka Kouji、Nakada Naoyuki、Miura Shin-ichi、Ryu Shoraku、Higashi Tatsuya、Ikarashi Yoshinori、Fujiwara Yasuhiro、Hamada Akinobu
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 34 Issue: 4 Pages: 209-216
- DOI
  10.1016/j.dmpk.2019.04.006
- NAID
  50014558508
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16132
[Journal Article] Fibroblast growth factor receptor-1 protein expression is associated with prognosis in estrogen receptor-positive/human epidermal growth factor receptor-2-negative primary breast cancer.2016
- Author(s)
  2.Tomiguchi M, Yamamoto Y, Yamamoto-Ibusuki M, Goto-Yamaguchi L, Fujiki Y, Fujiwara S, Sueta A, Hayashi M, Takeshita T, Inao T, Iwase H.
- Journal Title
  
  Cancer Sci.
  
  Volume: 107(4) Issue: 4 Pages: 491-8
- DOI
  10.1111/cas.12897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21237, KAKENHI-PROJECT-15K21239
[Journal Article] Visualizing spatial distribution of alectinib in murine brain using quantitative mass spectrometry imaging.2016
- Author(s)
  Aikawa H, Hayashi M, Ryu A, Yamashita M, Ohtsuka N, Nishidate M, Fujiwara Y, Hamada A.
- Journal Title
  
  Sci Rep
  
  Volume: 30 Issue: 1 Pages: 23749-23749
- DOI
  10.1038/srep23749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21239
[Journal Article] Successful ethinylestradio therapy for a metastatic breast cancer patient with heavily pre-treated with endocrine therapies.2016
- Author(s)
  Sueta A, Hayashi M, Fukugawa Y, Shimizu H, Yamamoto-Ibusuki M, Yamamoto Y, Iwase H.
- Journal Title
  
  Int Can Conf J.
  
  Volume: 5 Issue: 3 Pages: 126-126
- DOI
  10.1007/s13691-015-0241-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21239
[Journal Article] Associations between elastography findings and clinicopathological factors in breast cancer.2015
- Author(s)
  Hayashi M, Yamamoto Y, Sueta A, Tomiguchi M, Yamamoto-Ibusuki M, Kawasoe T, Hamada A, Iwase H.
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 94 Issue: 50 Pages: e2290-e2290
- DOI
  10.1097/md.0000000000002290
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21239
[Presentation] CYLD 発現低下による予後不良トリプルネガティブ型乳癌に対するNF-kB シグナル標的治療の有効性2021
- Author(s)
  新垣ひとみ、桑野明香里、平井ちか、末永尚輝、金丸歩美、三宅俊介、林光博、成田勇樹、齋藤秀之、城野博史
- Organizer
  第61回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Biological significance of CYLD downregulation in Triple negative breast cancer.2021
- Author(s)
  桑野明香里、平井ちか、末永尚輝、金丸歩美、新垣ひとみ、林光博、西郷智香、齋藤秀之、城野博史
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Clinical significance of CYLD down-regulation in invasiveness of triple negative breast cancer2019
- Author(s)
  Kuwano A, Hirai C, Suenaga N, Kanemaru A, Hayashi M, Saito H, Jono H
- Organizer
  第29回日本医療薬学会年会（International symposium）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Patient-derived xenograft（PDX）モデルを用いた新薬開発：J-PDXライブラリー事業2019
- Author(s)
  林　光博、後藤　悌、庄司　広和、米盛　勧、森実　千種、高橋　雅道、福原　傑、岩田　慎太郎、清水　俊雄、小川　千登世、高橋　真美、吉田　正行、平岡　伸介、加藤　健、田村　研治、山本　昇、今井　俊夫、間野　博行
- Organizer
  第17回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K16132
[Presentation] トリプルネガティブ型乳癌の悪性化形質獲得における腫瘍抑制遺伝子CYLD発現低下の臨床的意義2019
- Author(s)
  桑野明香里、平井ちか、末永尚輝、金丸歩美、三宅俊介、林光博、齋藤秀之、城野博史
- Organizer
  第59回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 乳癌におけるNGSパネルを用いた循環腫瘍DNAの包括的遺伝子型判定2019
- Author(s)
  林　光博、田村　研治、野口　瑛美、小島　勇貴、須藤　一起、下村　昭彦、谷岡　真樹、吉田　正行、米盛　勧、木下　貴之
- Organizer
  第27回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K16132
[Presentation] 乳癌薬物療法に対する耐性獲得における生命予後規定因子 CYLD 発現低下の臨床的意義の解明2018
- Author(s)
  城野博史、平井ちか、西郷智香、林光博、神力悟、安東由喜雄、齋藤秀之、岩瀬弘敬
- Organizer
  医療薬学フォーラム2018 第26回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 乳癌薬物療法における腫瘍抑制遺伝子 CYLD 発現低下の臨床的意義の解明2018
- Author(s)
  西郷智香、平井ちか、桑野明香里、林光博、岩瀬弘敬、齋藤秀之、城野博史
- Organizer
  第28回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] 乳癌薬物療法における腫瘍抑制遺伝子 CYLD 発現低下の臨床的意義の解明2018
- Author(s)
  城野博史、平井ちか、西郷智香、林光博、神力悟、安東由喜雄、岩瀬弘敬、齋藤秀之
- Organizer
  日本臨床化学会第58回年次学術集会
- Data Source
  KAKENHI-PROJECT-18H02591
[Presentation] Correlations between elastographic evaluations and clinicopathological factors in breast cancer2016
- Author(s)
  Mitsuhiro Hayashi, Hirotaka Iwase
- Organizer
  日本超音波医学会第89回学術集会
- Place of Presentation
  国立京都国際会館、京都市、京都
- Year and Date
  2016-05-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21239
[Presentation] 術前化学療法開始前のElastography FLR評価と治療効果との関係2016
- Author(s)
  林　光博、岩瀬　弘敬
- Organizer
  日本超音波医学会第89回学術集会
- Place of Presentation
  国立京都国際会館、京都市、京都
- Year and Date
  2016-05-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K21239
[Presentation] 乳癌硬度評価と臨床病理学的因子に関する検討、特にリンパ節転移との関係について2015
- Author(s)
  林　光博、冨口　麻衣、末田　愛子、藤原　沙織、山本　聡子、竹下　卓志、稲尾　瞳子、指宿　睦子、村上　敬一、山本　豊、岩瀬　弘敬
- Organizer
  第23回日本乳癌学会学術総会
- Place of Presentation
  東京国際フォーラム、千代田区、東京都
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-15K21239

1. Jono Hirofumi (40515483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. 齋藤秀之 (40225727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 大槻純男 (60323036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 松井啓隆 (60379849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. IBUSUKI Mutsuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 高橋雅道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 斎藤秀之

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results

hayashi mitsuhiro 林 光博

林 光博 ハヤシ ミツヒロ

Hayashi Mitsuhiro 林 光博

Research Projects

Research Products

Co-Researchers

乳癌PDXモデルを活用した循環腫瘍DNAに関するリバーストランスレーショナル研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishing novel molecular-targeted cancer therapies based on molecular diagnostics focusing on prognostic factor CYLD

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Associations between obesity, abnormal glucose/lipid metabolism, and clinico-biological factors in patients with breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Eribulin penetrates brain tumor tissue and prolongs survival of mice harboring intracerebral glioblastoma xenografts2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Applications of MALDI mass spectrometry imaging for pharmacokinetic studies during drug development2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Fibroblast growth factor receptor-1 protein expression is associated with prognosis in estrogen receptor-positive/human epidermal growth factor receptor-2-negative primary breast cancer.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Visualizing spatial distribution of alectinib in murine brain using quantitative mass spectrometry imaging.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Successful ethinylestradio therapy for a metastatic breast cancer patient with heavily pre-treated with endocrine therapies.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Associations between elastography findings and clinicopathological factors in breast cancer.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] CYLD 発現低下による予後不良トリプルネガティブ型乳癌に対するNF-kB シグナル標的治療の有効性2021

Author(s)

Organizer

Data Source

[Presentation] Biological significance of CYLD downregulation in Triple negative breast cancer.2021

Author(s)

Organizer

Data Source

[Presentation] Clinical significance of CYLD down-regulation in invasiveness of triple negative breast cancer2019

Author(s)

Organizer

Data Source

[Presentation] Patient-derived xenograft（PDX）モデルを用いた新薬開発：J-PDXライブラリー事業2019

Author(s)

Organizer

Data Source

[Presentation] トリプルネガティブ型乳癌の悪性化形質獲得における腫瘍抑制遺伝子CYLD発現低下の臨床的意義2019

Author(s)

Organizer

Data Source

[Presentation] 乳癌におけるNGSパネルを用いた循環腫瘍DNAの包括的遺伝子型判定2019

Author(s)

Organizer

Data Source

[Presentation] 乳癌薬物療法に対する耐性獲得における生命予後規定因子 CYLD 発現低下の臨床的意義の解明2018

hayashi mitsuhiro 林光博

林光博ハヤシミツヒロ

Hayashi Mitsuhiro 林光博