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Kakiuchi Toshihiko  垣内 俊彦

Researcher Number 50737864
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-9995-5522
Affiliation (Current) 2025: 佐賀大学, 医学部附属病院, 病院講師
Affiliation (based on the past Project Information) *help 2023 – 2025: 佐賀大学, 医学部附属病院, 病院講師
2021 – 2024: 佐賀大学, 医学部, 病院講師
2020: 佐賀大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 58030:Hygiene and public health-related: excluding laboratory approach / Basic Section 52030:Psychiatry-related
Except Principal Investigator
Basic Section 58030:Hygiene and public health-related: excluding laboratory approach / Basic Section 53010:Gastroenterology-related / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords
Principal Investigator
ヘリコバクター・ピロリ菌 / ヘリコバクター・ピロリ / 薬剤耐性感受性試験 / テーラーメイド除菌療法 / テーラーメイド療法 / 薬剤耐性 / 除菌治療 / 自閉症スペクトラム症 / フリーラジカル / サイトカインプロファイル / 腸内細菌叢 / 自閉スペクトラム症 … More
Except Principal Investigator
… More 除菌治療 / 胃がん予防 / 医療費 / 経済分析 / 中高生 / H. pylori / ピロリ菌 / 除菌後フォロー体制 / 胃組織DNAメチル化解析 / 除菌治療後胃粘膜 / 診断精度 / 中学生ピロリ菌検診 / 若年者 / 除菌後胃がん / ヘリコバクター・ピロリ / エピジェネティクス / ペプチドグリカン / 腸内細菌叢 / 炎症性腸疾患 / 自閉スペクトラム症 / ピロリ菌感染対策 / アンケート / 行政主導 / ピロリ菌除菌 / ピロリ菌検診 / 胃癌予防 / 検診 / マニュアル / スクリーニング検査 / 全国調査 / 中学生ピロリ菌検査 / 自治体調査 / 検査と治療 / ピロリ菌検査 / 中学生 / 胃がん / 累積罹患リスク / 既存統計資料 / 罹患リスク比 / ピロリ菌感染率 / 若年期 Less
  • Research Projects

    (7 results)
  • Research Products

    (42 results)
  • Co-Researchers

    (14 People)
  •  Research for common factors associated with the development of autism spectrum disorder and inflammatory bowel disease

    • Principal Investigator
      松尾 宗明
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Saga University
  •  Verification of Helicobacter pylori screening for junior high school students: Towards test accuracy and establishment of follow-up system after treatment

    • Principal Investigator
      奥田 真珠美
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Hyogo Medical University
  •  便を用いた新規開発試薬によるピロリ菌テーラーメイド除菌療法の社会実装性の評価Principal Investigator

    • Principal Investigator
      垣内 俊彦
    • Project Period (FY)
      2024 – 2028
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
    • Research Institution
      Saga University
  •  行政主導の若年者向けピロリ菌感染対策による胃がん予防プログラムの検討

    • Principal Investigator
      川合 紗世
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
    • Research Institution
      Aichi Medical University
  •  Screening and treatment of Helicobacter pylori for junior high school students in Japan - a nationwide survey of local government on implementation status

    • Principal Investigator
      Okuda Masumi
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
    • Research Institution
      Hyogo Medical University
  •  Cost-effectiveness Analysis of Preventing H. pylori Infection to Reduce Gastric Cancer Risk in the Next Generation

    • Principal Investigator
      Kawai Sayo
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
    • Research Institution
      Aichi Medical University
  •  Correlation between H. pylori and autism spectrum disease by intestinal microbiotaPrincipal Investigator

    • Principal Investigator
      Kakiuchi Toshihiko
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Saga University

All 2024 2023 2022 2021 2020

All Journal Article Presentation Book

  • [Book] 小児内科2024

    • Author(s)
      垣内俊彦
    • Total Pages
      6
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-24K20220
  • [Book] 佐賀県若年者H. pylori検診における現状と問題2022

    • Author(s)
      垣内俊彦
    • Total Pages
      5
    • Publisher
      日本ヘリコバクター学会誌
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Book] 便検体を用いたHelicobacter pyloriクラリスロマイシン薬剤耐性遺伝子変異検出試薬の臨床性能評価2022

    • Author(s)
      垣内俊彦
    • Total Pages
      3
    • Publisher
      日本ヘリコバクター学会誌
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Book] Helicobacter Research2021

    • Author(s)
      垣内俊彦
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Journal Article] Parental Knowledge and Attitudes Towards Helicobacter Pylori Screening in Adolescents: A School-Based Questionnaire Study Among Guardians of Junior High School Students in Yokosuka City, Japan2024

    • Author(s)
      Saito Hiroaki、Uchiyama Taiga、Matsuoka Mikio、Kakiuchi Toshihiko、Eguchi Yuichiro、Tsubokura Masaharu、Mizuno Yasuhiro
    • Journal Title

      Journal of Gastrointestinal Cancer

      Volume: 55 Issue: 3 Pages: 1274-1281

    • DOI

      10.1007/s12029-024-01082-y

    • Data Source
      KAKENHI-PROJECT-20K16670, KAKENHI-PROJECT-24K20220
  • [Journal Article] Non-Helicobacter pylori Helicobacter as a cause of duodenal ulcer in children2024

    • Author(s)
      Kakiuchi Toshihiko
    • Journal Title

      Journal of the Formosan Medical Association

      Volume: 123 Issue: 10 Pages: 1115-1115

    • DOI

      10.1016/j.jfma.2024.07.019

    • Data Source
      KAKENHI-PROJECT-20K16670, KAKENHI-PROJECT-24K20220
  • [Journal Article] Accurate evaluation of pediatric Helicobacter pylori heteroresistance contributes to further improving the quality of tailored therapy2024

    • Author(s)
      Kakiuchi Toshihiko
    • Journal Title

      Pediatric Research

      Volume: 95 Issue: 7 Pages: 1696-1697

    • DOI

      10.1038/s41390-024-03072-z

    • Data Source
      KAKENHI-PROJECT-20K16670, KAKENHI-PROJECT-24K20220
  • [Journal Article] Important Recommendations Regarding the Test-and-Treat Strategy for <i>Helicobacter pylori</i> Infection in Children2024

    • Author(s)
      Kakiuchi Toshihiko
    • Journal Title

      INQUIRY: The Journal of Health Care Organization, Provision, and Financing

      Volume: 61

    • DOI

      10.1177/00469580231222649

    • Data Source
      KAKENHI-PROJECT-20K16670, KAKENHI-PROJECT-24K20220
  • [Journal Article] Efficacy and safety of vonoprazan-based regimen for Helicobacter pylori eradication therapy in Japanese adolescents: a prospective multicenter study2023

    • Author(s)
      Kakiuchi T, Matsuo M, Endo H, Sakata Y, Esaki M, Noda T, Imamura I, Hashiguchi K, Ogata S, Fujioka Y, Hanada K, Fukuda K, Yoshimura M, Kajiwara T, Yamamoto K, Yamaguchi D, Kawakubo H, Matsunaga T, Sumino M, Matsunaga K, Muro E, Watanabe A, Fujimoto K
    • Journal Title

      J Gastroenterol

      Volume: 58 Issue: 3 Pages: 196-204

    • DOI

      10.1007/s00535-022-01942-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Journal Article] Case report: A pediatric case of repeated false-positive urea breath test for Helicobacter pylori without decreased gastric acid secretion2023

    • Author(s)
      Nishino M, Kakiuchi T, Fukuda K, Yoshiura M
    • Journal Title

      Front Med (Lausanne)

      Volume: 10 Pages: 1267180-1267180

    • DOI

      10.3389/fmed.2023.1267180

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Journal Article] 中学生ピロリ菌検査と除菌治療自治体向けマニュアル.2023

    • Author(s)
      奥田真珠美、垣内俊彦、菊地正悟、草野央、間部克裕、加藤元嗣、村上和成、日本ヘリコバクター学会研究推進委員会.若年者ヘリコバクター感染に関する委員会.
    • Journal Title

      日本ヘリコバクター学会誌

      Volume: 24 Pages: 92-97

    • Data Source
      KAKENHI-PROJECT-21K10485
  • [Journal Article] Management of Helicobacter pylori infection in paediatric patients in Europe2023

    • Author(s)
      Kakiuchi T
    • Journal Title

      Infection

      Volume: 51(3) Issue: 3 Pages: 797-798

    • DOI

      10.1007/s15010-022-01969-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Journal Article] A true point-of-care molecular testing method for tailored therapy for Helicobacter pylori eradication2023

    • Author(s)
      Kakiuchi T
    • Journal Title

      EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY

      Volume: 17(3) Issue: 3 Pages: 309-310

    • DOI

      10.1080/17474124.2023.2179986

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Journal Article] Commentary: Tailored therapy for Helicobacter pylori eradication: A systematic review and meta-analysi2022

    • Author(s)
      Kakiuchi T, Yoshiura M
    • Journal Title

      Front Pharmacol

      Volume: 13 Pages: 1090776-1090776

    • DOI

      10.3389/fphar.2022.1090776

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Journal Article] Clinical evaluation of a novel stool antigen test using bioluminescent enzyme immunoassay for detection of Helicobacter pylori2022

    • Author(s)
      Kakiuchi T, Matsuo M, Sakata Y, Fujimoto K
    • Journal Title

      Can J Gastroenterol Hepatol

      Volume: 2022 Pages: 5571542-5571542

    • DOI

      10.1155/2022/5571542

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Journal Article] Smart Gene? as an effective non‐invasive point‐of‐care test to detect <scp> <i>Helicobacter pylori</i> </scp> clarithromycin‐resistant mutation2022

    • Author(s)
      Kakiuchi Toshihiko、Okuda Masumi、Matsuo Muneaki、Fujimoto Kazuma
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: 37 Issue: 9 Pages: 1719-1725

    • DOI

      10.1111/jgh.15887

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K10485, KAKENHI-PROJECT-20K16670
  • [Journal Article] High Prevalence of Helicobacter pylori Infection in Special Needs Schools in Japan2021

    • Author(s)
      Kakiuchi Toshihiko、Takamori Ayako、Matsuo Muneaki
    • Journal Title

      Frontiers in Pediatrics

      Volume: 9 Pages: 697200-697200

    • DOI

      10.3389/fped.2021.697200

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Journal Article] Clinical Evaluation of a Novel Point-of-Care Assay To Detect Mycoplasma pneumoniae and Associated Macrolide-Resistant Mutations2021

    • Author(s)
      Kakiuchi Toshihiko、Miyata Ippei、Kimura Reiji、Shimomura Goh、Shimomura Kunihisa、Yamaguchi Satoru、Yokoyama Takato、Ouchi Kazunobu、Matsuo Muneaki
    • Journal Title

      Journal of Clinical Microbiology

      Volume: 59 Issue: 7

    • DOI

      10.1128/jcm.03245-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Journal Article] <i>Helicobacter pylori</i> infection-induced changes in the intestinal microbiota of 14-year-old or 15-year-old Japanese adolescents: a cross-sectional study2021

    • Author(s)
      Kakiuchi Toshihiko、Tanaka Yoshiki、Ohno Hiroshi、Matsuo Muneaki、Fujimoto Kazuma
    • Journal Title

      BMJ Open

      Volume: 11 Issue: 7 Pages: e047941-e047941

    • DOI

      10.1136/bmjopen-2020-047941

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Journal Article] Gut microbiota changes related to Helicobacter pylori eradication with vonoprazan containing triple therapy among adolescents: a prospective multicenter study2021

    • Author(s)
      Kakiuchi Toshihiko、Yamamoto Kentaroh、Imamura Ichiro、Hashiguchi Kazutoshi、Kawakubo Hiroharu、Yamaguchi Daisuke、Fujioka Yasuhiko、Okuda Masumi
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 755-755

    • DOI

      10.1038/s41598-020-80802-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09144, KAKENHI-PROJECT-21K10485, KAKENHI-PROJECT-20K16670
  • [Journal Article] Effect of probiotics during vonoprazan‐containing triple therapy on gut microbiota in Helicobacter pylori infection: A randomized controlled trial2020

    • Author(s)
      Kakiuchi Toshihiko、Mizoe Akihiko、Yamamoto Kentaroh、Imamura Ichiro、Hashiguchi Kazutoshi、Kawakubo Hiroharu、Yamaguchi Daisuke、Fujioka Yasuhiko、Nakayama Aiko、Okuda Masumi、Matsuo Muneaki
    • Journal Title

      Helicobacter

      Volume: 25 Issue: 3

    • DOI

      10.1111/hel.12690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09144, KAKENHI-PROJECT-20K16670
  • [Journal Article] Assessment of a novel method to detect clarithromycin-resistance Helicobacter pylori using a stool antigen test reagent2020

    • Author(s)
      Kakiuchi T, Hashiguchi K, Imamura I, Nakayama A, Takamori A, Okuda M, Matsuo M
    • Journal Title

      BMC Gastroenterol.

      Volume: 20 Issue: 1 Pages: 397-397

    • DOI

      10.1186/s12876-020-01549-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] 胃酸分泌低下を有さないヘリコバクター・ピロリ泥沼除菌の小児例2024

    • Author(s)
      西野将史, 垣内俊彦
    • Organizer
      第30回日本ヘリコバクター学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] Helicobacter pylori 感染の診断と治療のガイドライン改訂版:胃がん予防・未成年2024

    • Author(s)
      奥田真珠美、垣内俊彦
    • Organizer
      第30回日本ヘリコバクター学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] 便検体を用いたヘリコバクター・ピロリ菌のテーラーメイド療法2024

    • Author(s)
      垣内俊彦
    • Organizer
      第31回日本ヘリコバクター学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-24K20220
  • [Presentation] Screening and eradication of Helicobacter pylori for junior high school students in Japan. Nationwide survey for local governments regarding conducted status and methods.2024

    • Author(s)
      Masumi Okuda, Mototsugu Kato, Shogo Kikuchi, Toshihiko Kakiuchi, Tomoko Lee, Hideki Shimomura, Yasuhiro Takeshima.
    • Organizer
      European Helicobacter&Microbiota Study Group 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K10485
  • [Presentation] Screening and eradication of Helicobacter pylori for junior high school students in Japan. Nationwide survey for local governments regarding conducted status and methods.2024

    • Author(s)
      Masumi Okuda, Mototsugu Kato, Shogo Kikuchi, Toshihiko Kakiuchi, Tomoko Lee, Hideki Shimomura, Yasuhiro Takeshima
    • Organizer
      European Helicobacter and Microbiota Study Group 2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24K11180
  • [Presentation] Detection of the Helicobacter pylori clarithromycin resistance gene in stool samples2023

    • Author(s)
      Okuda M, Kakiuchi T, Ebisu K, Torii K, Hotta A, Fujino T, Saito M, Okugawa T, Takeshima T.
    • Organizer
      The 19th Korea-Japan Joint Symposium on Helicobacter Infection
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K10485
  • [Presentation] Strategies for Helicobacter Pylori Screening and Treatment in Junior High School Students to Eliminate Gastric Cancer2022

    • Author(s)
      Toshihiko Kakiuchi
    • Organizer
      APPSPGHAN 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] 中学3年生を対象としたピロリ菌感染対策事業の胃がん予防に対する費用効果分析2022

    • Author(s)
      川合 紗世、垣内 俊彦、篠壁 多恵、林 櫻松、菊地 正悟
    • Organizer
      第33回 日本疫学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K10482
  • [Presentation] BLEIA法に基づくヘリコバクター・ピロリ抗原体外診断薬の臨床性能評価2022

    • Author(s)
      垣内俊彦 藤本一眞
    • Organizer
      第28回日本ヘリコバクター学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] 便検体を用いたHelicobacter pyloriクラリスロマイシン薬剤耐性遺伝子変異検出試薬の臨床性能評価2021

    • Author(s)
      垣内俊彦 奥田真珠美
    • Organizer
      第48回日本小児栄養消化器肝臓学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] ボノプラザンでの小児H. pylori除菌時のブリストルスケールを用いた便性状評価2021

    • Author(s)
      垣内俊彦 遠藤広貴 中山愛子 高守史子 松尾宗明 藤本一眞
    • Organizer
      第26回日本ヘリコバクター学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] 便検体を用いたQprobe法を原理とするCAM耐性変異が鑑別可能なヘリコバクター・ピロリ遺伝子簡易検査試薬の検討2021

    • Author(s)
      垣内俊彦 中山愛子 鳥井邦明 松尾宗明 藤本一眞
    • Organizer
      第26回日本ヘリコバクター学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] 全自動遺伝子解析装置Smart GeneによるQProbe法を用いたMycoplasma pneumoniaeとマクロライド耐性変異検出試薬の臨床評価と抗菌薬選択への寄与2021

    • Author(s)
      垣内俊彦 宮田一平 木村礼ニ 下村豪 下村国寿 山口覚 横山隆人 尾内一信 松尾宗明
    • Organizer
      第88回佐賀小児科地方会
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] 便検体を用いたHelicobacter pyloriクラリスロマイシン薬剤耐性遺伝子変異検出試薬の臨床性能評価2021

    • Author(s)
      垣内俊彦、奥田真珠美
    • Organizer
      第48回日本小児栄養消化器肝臓学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K10485
  • [Presentation] 佐賀県若年者H. pylori検診における現状と問題点2021

    • Author(s)
      垣内俊彦 遠藤広貴 藤本一眞
    • Organizer
      第27回日本ヘリコバクター学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] ボノプラザンでの小児H. pylori除菌時の腸内細菌叢および有害事象に対するプロバイオティクス効果2021

    • Author(s)
      垣内俊彦 溝江昭彦 山元謙太郎 今村一郎 橋口一利 川久保洋晴 山口太輔  藤岡康彦 中山愛子 奥田真珠美 松尾宗明
    • Organizer
      第26回日本ヘリコバクター学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] 未来へ向けた胃がん対策推進事業、佐賀県全県における中学生ピロリ菌検査・除菌(パネルディスカッション)2020

    • Author(s)
      藤本一眞 垣内俊彦 遠藤広貴
    • Organizer
      第62回日本消化器病学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] ボノプラザンを含む三剤療法における小児(15歳)H. pylori除菌時のブリストルスケールを用いた便性状評価2020

    • Author(s)
      垣内俊彦 中山愛子 藤本一眞
    • Organizer
      第47回日本小児栄養消化器肝臓学会
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] 佐賀県全県下中学3年生ピロリ菌検診の現状2020

    • Author(s)
      垣内俊彦 遠藤広貴 藤本一眞
    • Organizer
      第116回日本消化器病学会九州支部例会
    • Data Source
      KAKENHI-PROJECT-20K16670
  • [Presentation] ボノプラザンを含む三剤療法における小児(15歳)H. pylori除菌時の腸内細菌叢の変化2020

    • Author(s)
      垣内俊彦 中山愛子 奥田真珠美
    • Organizer
      第47回日本小児栄養消化器肝臓学会
    • Data Source
      KAKENHI-PROJECT-20K16670
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