Matsuzaki Yasunori 松崎泰教

… Alternative Names

MATSUZAKI Yasunori 松崎泰教

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Researcher Number	50738200
Other IDs	https://orcid.org/0000-0003-3974-064X
Affiliation (Current)	2025: 群馬大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2024: 群馬大学, 大学院医学系研究科, 助教 2017 – 2018: 群馬大学, 大学院医学系研究科, 助教 2015: 群馬大学, 医学(系)研究科(研究院), 助教 2014: 群馬大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Neurophysiology / General neuroscience / Basic Section 90120:Biomaterials-related Except Principal Investigator Neurology / Neurophysiology / General neuroscience
Keywords	Principal Investigator AAVベクター / 非ヒト霊長類 / マーモセット / AAV / アデノ随伴ウイルスベクター / プロモーター / マイクログリア / mGluR1 / CRISPR/Cas9 / レンチウイルスベクター … More / blood-brain barrier / AAV-PHP.B / CRISPR-Cas9 / 脊髄小脳変性症 / ポリグルタミン病 / ATXN1 / Ataxin-1 / コモンマーモセット / Ataxin / ATXN / 脊髄小脳失調症 / 脳神経科学 … More Except Principal Investigator 神経科学 / 遺伝子 / 脳神経疾患 / SCA1 / AAVベクター / 脊髄小脳失調症 / プルキンエ細胞 / 小脳 / 再生医学 / アデノ随伴ウイルスベクター / 遺伝子治療 / ウイルスベクター / AAV / ゲノム編集 / CRISPR/Cas9 / 細胞種特異的プロモーター / パッチクランプ / ロータロッド / ポリグルタミン病 / 脊髄小脳変性症 / 生理学 / シグナル伝達 / 運動記憶 / SCA3 / 運動失調 / バクロフェン / 運動学習 / mGluR1 Less

非ヒト霊長類ミクログリア特異的なAAVベクターの開発Principal Investigator
- Principal Investigator
  
  松崎泰教
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Gunma University
Development of the in vivo knockout system in the marmoset brain using AAV-PHP.BPrincipal Investigator
- Principal Investigator
  
  Matsuzaki Yasunori
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Gunma University
Development of gene therapy against neurodegenerative diseases using CRISPR/Cas9-based genome editing
- Principal Investigator
  
  Hirai Hirokazu
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Gunma University
Elucidation of cellular and nuclear signals that regulate motor learning
- Principal Investigator
  
  Hirai Hirokazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Gunma University
Generation of inherited spinocerebellar ataxia model marmoset and assessment of drug treatmentPrincipal Investigator
- Principal Investigator
  
  Matsuzaki Yasunori
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Gunma University

All 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Neurotropic Properties of AAV-PHP.B Are Shared among Diverse Inbred Strains of Mice2019
- Author(s)
  Matsuzaki Yasunori、Tanaka Masami、Hakoda Sachiko、Masuda Tatsuki、Miyata Ryota、Konno Ayumu、Hirai Hirokazu
- Journal Title
  
  Molecular Therapy
  
  Volume: 27 Issue: 4 Pages: 700-704
- DOI
  10.1016/j.ymthe.2019.02.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K14929, KAKENHI-PROJECT-18H02521
[Journal Article] Pharmacological enhancement of retinoid-related orphan receptor α function mitigates spinocerebellar ataxia type 3 pathology2019
- Author(s)
  Watanave Masashi、Hoshino Chiaki、Konno Ayumu、Fukuzaki Yumi、Matsuzaki Yasunori、Ishitani Tohru、Hirai Hirokazu
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 121 Pages: 263-273
- DOI
  10.1016/j.nbd.2018.10.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K14929
[Journal Article] Effects of Neutralizing Antibody Production on AAV-PHP.B-Mediated Transduction of the Mouse Central Nervous System2018
- Author(s)
  Shinohara Yoichiro、Konno Ayumu、Nitta Keisuke、Matsuzaki Yasunori、Yasui Hiroyuki、Suwa Junya、Hiromura Keiju、Hirai Hirokazu
- Journal Title
  
  Molecular Neurobiology
  
  Volume: - Issue: 6 Pages: 4203-4214
- DOI
  10.1007/s12035-018-1366-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K14929, KAKENHI-PROJECT-18H02521
[Journal Article] Contribution of Thyrotropin-Releasing Hormone to Cerebellar Long-Term Depression and Motor Learning2018
- Author(s)
  Watanave Masashi、Matsuzaki Yasunori、Nakajima Yasuyo、Ozawa Atsushi、Yamada Masanobu、Hirai Hirokazu
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 12
- DOI
  10.3389/fncel.2018.00490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K14929
[Journal Article] Intravenous administration of the adeno-associated virus-PHP.B capsid fails to upregulate transduction efficiency in the marmoset brain2018
- Author(s)
  Matsuzaki Yasunori、Konno Ayumu、Mochizuki Ryuta、Shinohara Yoichiro、Nitta Keisuke、Okada Yukihiro、Hirai Hirokazu
- Journal Title
  
  Neuroscience Letters
  
  Volume: 665 Pages: 182-188
- DOI
  10.1016/j.neulet.2017.11.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K14929, KAKENHI-PROJECT-15H04254, KAKENHI-PROJECT-16K15477, KAKENHI-PROJECT-15K18330
[Journal Article] Regulatory connection between the expression level of classical protein kinase C and pruning of climbing fibers from cerebellar Purkinje cells2017
- Author(s)
  Takahashi Nobutaka、Shuvaev Anton N.、Konno Ayumu、Matsuzaki Yasunori、Watanave Masashi、Hirai Hirokazu
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 143 Issue: 6 Pages: 660-670
- DOI
  10.1111/jnc.14239
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K14929, KAKENHI-PROJECT-15H04254, KAKENHI-PROJECT-16K15477, KAKENHI-PROJECT-15K18330
[Journal Article] Minimal Purkinje Cell-Specific PCP2/L7 Promoter Virally Available for Rodents and Non-human Primates2017
- Author(s)
  Nitta Keisuke、Matsuzaki Yasunori、Konno Ayumu、Hirai Hirokazu
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 6 Pages: 159-170
- DOI
  10.1016/j.omtm.2017.07.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K14929, KAKENHI-PROJECT-15H04254, KAKENHI-PROJECT-16K15477, KAKENHI-PROJECT-15K18330
[Journal Article] Plasticity of the developmentally arrested staggerer cerebellum in response to exogenous RORα.2016
- Author(s)
  Iizuka A, Matsuzaki Y, Konno A, Hirai H.
- Journal Title
  
  Brain Structure and Function
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04254
[Journal Article] Transduction Profile of the Marmoset Central Nervous System Using Adeno-Associated Virus Serotype 9 Vectors2016
- Author(s)
  Yasunori Matsuzaki, Ayumu Konno, Ryo Mukai, Fumiaki Honda, Masafumi Hirato, Yuhei Yoshimoto, Hirokazu Hirai
- Journal Title
  
  Molecular Neurobiology
  
  Volume: in press Pages: 1-14
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26890005
[Journal Article] Plasticity of the developmentally arrested staggerer cerebellum in response to exogenous RORα2015
- Author(s)
  Akira Iizuka, Yasunori Matsuzaki, Ayumu Konno, Hirokazu Hirai
- Journal Title
  
  Brain Structure and Function
  
  Volume: in press Pages: 1-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26890005
[Presentation] Mouse strain-dependent BBB (blood-brain barrier) permeability of AAV-PHP.B2019
- Author(s)
  Yasunori Matsuzaki, Masami Tanaka, Sachiko Hakoda, Tatsuki Masuda, Ryota Miyata, Ayumu Konnno, Hirokazu Hirai
- Organizer
  9th FAOPS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K14929
[Presentation] Minimal Purkinje Cell-Specific PCP2/L7 Promoter Virally Available for Rodents and Non-human Primates2018
- Author(s)
  Yasunori Matsuzaki, Keisuke Nitta, Ayumu Konno, Hirokazu Hirai
- Organizer
  8th international symposium of SRCA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K14929
[Presentation] Generation of a marmoset model of spinocerebellar ataxia type 3 via AAV9 vector-mediated gene transfer2016
- Author(s)
  Ayumu Konno, Yasunori Matsuzaki, Hirokazu Hirai
- Organizer
  Neuroscience 2016
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04254

1. Hirai Hirokazu (70291086)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. HOSOI Nobutake (90543570)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KONNO Ayumu (40509048)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results

Matsuzaki Yasunori 松崎 泰教

MATSUZAKI Yasunori 松崎 泰教

Research Projects

Research Products

Co-Researchers

非ヒト霊長類ミクログリア特異的なAAVベクターの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the in vivo knockout system in the marmoset brain using AAV-PHP.BPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of gene therapy against neurodegenerative diseases using CRISPR/Cas9-based genome editing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of cellular and nuclear signals that regulate motor learning

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation of inherited spinocerebellar ataxia model marmoset and assessment of drug treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Neurotropic Properties of AAV-PHP.B Are Shared among Diverse Inbred Strains of Mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pharmacological enhancement of retinoid-related orphan receptor α function mitigates spinocerebellar ataxia type 3 pathology2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of Neutralizing Antibody Production on AAV-PHP.B-Mediated Transduction of the Mouse Central Nervous System2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Contribution of Thyrotropin-Releasing Hormone to Cerebellar Long-Term Depression and Motor Learning2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intravenous administration of the adeno-associated virus-PHP.B capsid fails to upregulate transduction efficiency in the marmoset brain2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulatory connection between the expression level of classical protein kinase C and pruning of climbing fibers from cerebellar Purkinje cells2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Minimal Purkinje Cell-Specific PCP2/L7 Promoter Virally Available for Rodents and Non-human Primates2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Plasticity of the developmentally arrested staggerer cerebellum in response to exogenous RORα.2016

Author(s)

Journal Title

Data Source

[Journal Article] Transduction Profile of the Marmoset Central Nervous System Using Adeno-Associated Virus Serotype 9 Vectors2016

Author(s)

Journal Title

Data Source

[Journal Article] Plasticity of the developmentally arrested staggerer cerebellum in response to exogenous RORα2015

Author(s)

Matsuzaki Yasunori 松崎泰教

MATSUZAKI Yasunori 松崎泰教