ZHOU HEYING 周赫英

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Zhou Heying 周赫英

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Researcher Number	50750080
Other IDs
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究員
Affiliation (based on the past Project Information) *help	2019 – 2021: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 2015 – 2017: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Applied health science
Keywords	Principal Investigator 骨格筋 / サルコペニア / 筋萎縮 / 筋衛星細胞 / 筋再生 / バイオマーカー / 骨格筋機能

Development of a method for the prevention and treatment of sarcopenia using high-quality cultured human muscle cells.Principal Investigator
- Principal Investigator
  
  Zhou Heying
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Blood concentration of postsynaptic membrane protein A reflects physical performance in aged peoplePrincipal Investigator
- Principal Investigator
  
  Zhou Heying
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology

All 2021 2020 2019 2017 2016 2015

All Journal Article Presentation

[Journal Article] Mesenchymal Bmp3b expression maintains skeletal muscle integrity and decreases in age-related sarcopenia2021
- Author(s)
  Uezumi Akiyoshi、Ikemoto-Uezumi Madoka、Zhou Heying、Kurosawa Tamaki、Yoshimoto Yuki、Nakatani Masashi、Hitachi Keisuke、Yamaguchi Hisateru、Wakatsuki Shuji、Araki Toshiyuki、Morita Mitsuhiro、Yamada Harumoto、Toyoda Masashi、Kanazawa Nobuo、Nakazawa Tatsu、Hino Jun、Fukada So-ichiro、Tsuchida Kunihiro
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 131 Issue: 1
- DOI
  10.1172/jci139617
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09614, KAKENHI-PROJECT-19K11710, KAKENHI-PROJECT-20K09423, KAKENHI-PROJECT-20K11247, KAKENHI-PROJECT-18K09122, KAKENHI-PROJECT-19H04063, KAKENHI-PROJECT-19H03427
[Journal Article] Increased MFG‐E8 at neuromuscular junctions is an exacerbating factor for sarcopenia‐associated denervation2021
- Author(s)
  Ikemoto‐Uezumi Madoka、Zhou Heying、Kurosawa Tamaki、Yoshimoto Yuki、Toyoda Masashi、Kanazawa Nobuo、Nakazawa Tatsu、Morita Mitsuhiro、Tsuchida Kunihiro、Uezumi Akiyoshi
- Journal Title
  
  Aging Cell
  
  Volume: 21 Issue: 1 Pages: 1-15
- DOI
  10.1111/acel.13536
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11710, KAKENHI-PROJECT-19H03427, KAKENHI-PROJECT-19K09614, KAKENHI-PROJECT-21K19753
[Journal Article] Reduced expression of calcitonin receptor is closely associated with age-related loss of the muscle stem cell pool.2019
- Author(s)
  Madoka Ikemoto-Uezumi, Akiyoshi Uezumi, Lidan Zhang, Heying Zhou, Naohiro Hashimoto, Kikuo Okamura, Yasumoto Matsui, Koji Tsukazaki, Tohru Hosoyama, Masashi Nakatani, Mitsuhiro Morita, Harumoto Yamada, Kunihiro Tsuchida, So-ichiro Fukada
- Journal Title
  
  JSCM Rapid Communications
  
  Volume: 2 Issue: 1 Pages: 1-13
- DOI
  10.1002/j.2617-1619.2019.tb00012.x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11710, KAKENHI-PROJECT-19H04000
[Journal Article] Femoral osteoporosis is more common than lumbar osteoporosis in patients with Werner syndrome2017
- Author(s)
  Mori Seijiro、Zhou Heying、Yamaga Masaya、Takemoto Minoru、Yokote Koutaro
- Journal Title
  
  Geriatr Gerontol Int.
  
  Volume: 17 Issue: 5 Pages: 854-856
- DOI
  10.1111/ggi.12960
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09229, KAKENHI-PROJECT-17K19643, KAKENHI-PROJECT-17H01558, KAKENHI-PROJECT-15K01743
[Journal Article] Implementation of personalized medicine for fracture risk assessment in osteoporosis.2016
- Author(s)
  Mori S, Zhou H
- Journal Title
  
  Geriatr Gerontol Int.
  
  Volume: 16 Suppl 1 Issue: S1 Pages: 57-65
- DOI
  10.1111/ggi.12721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01743
[Journal Article] Genetic risk score based on the prevalence of vertebral fracture in Japanese women with osteoporosis2016
- Author(s)
  Heying Zhou, Seijiro Mori, Tatsuro Ishizaki, Atsushi Takahashi, Koichi Matsuda, Yukihiro Koretsune, Shiro Minami, Masahiko Higashiyama, Shinji Imai, Kozo Yoshimori, Minoru Doita, Akira Yamada, Satoshi Nagayama, Kazuo Kaneko, Satoshi Asai, Masaki Shiono, Michiaki Kubo, Hideki Ito
- Journal Title
  
  Bone Reports
  
  Volume: 5 Pages: 168-172
- DOI
  10.1016/j.bonr.2016.07.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01743
[Presentation] Muscle specific aging signature of PDGFRα-positive stromal cells underlies the development of age-related sarcopenia2021
- Author(s)
  黒澤珠希、梶典幸、上住円、周赫英、湊圭太郎、上住聡芳、堀正敏
- Organizer
  第９４回日本薬理学会
- Data Source
  KAKENHI-PROJECT-19K11710
[Presentation] 様々な臓器に存在するPDGFRα陽性間質細胞の比較解析2021
- Author(s)
  黒澤珠希, 梶典幸, 上住円, 周赫英, 吉本由紀, 湊圭太郎, 堀正敏 , 上住聡芳
- Organizer
  第7回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-19K11710
[Presentation] ScxGFP iPS細胞を用いたin vitro腱・靭帯細胞分化誘導システムの確立2020
- Author(s)
  吉本由紀、黒澤珠希、周赫英、上住円、外丸祐介、宿南知佐、上住聡芳
- Organizer
  第６回日本筋学会
- Data Source
  KAKENHI-PROJECT-19K11710
[Presentation] 神経筋結合部におけるMFG-E8の蓄積は加齢性脱神経の一因となる2020
- Author(s)
  上住円、周赫英、吉本由紀、黒澤珠希、湊圭太郎、上住聡芳
- Organizer
  第６回日本筋学会
- Data Source
  KAKENHI-PROJECT-19K11710
[Presentation] PDGFRα陽性間質細胞の臓器特異性から探るサルコペニアのメカニズム2020
- Author(s)
  黒澤珠希、梶典幸、上住円、周赫英、湊圭太郎、堀正敏、上住聡芳
- Organizer
  第６回日本筋学会
- Data Source
  KAKENHI-PROJECT-19K11710
[Presentation] 高品質なヒト骨格筋前駆細胞の濃縮方法2020
- Author(s)
  周赫英、上住円、黒澤珠希、豊田雅士、吉本由紀、上住聡芳
- Organizer
  第６回日本筋学会
- Data Source
  KAKENHI-PROJECT-19K11710
[Presentation] カルシトニン受容体の発現低下は加齢性の骨格筋幹細胞減少に寄与する2019
- Author(s)
  上住円、上住聡芳、張礫丹、周赫英、橋下有弘、岡村菊夫、松井康素、塚崎晃士、細山徹、中谷直史、森田充浩、山田治基、土田邦博、深田宗一朗
- Organizer
  日本筋学会第5回学術集会
- Data Source
  KAKENHI-PROJECT-19K11710
[Presentation] 様々な臓器に存在するPDGFRα陽性間質細胞の比較解析2019
- Author(s)
  黒澤珠希、梶典幸、上住円、周赫英、堀正敏、上住聡芳
- Organizer
  日本筋学会第5回学術集会
- Data Source
  KAKENHI-PROJECT-19K11710
[Presentation] ヒト骨格筋由来前駆細胞の品質に関与する因子の同定2019
- Author(s)
  周赫英、上住円、黒澤珠希、豊田雅士、吉本由紀、上住聡芳
- Organizer
  第７回若手による骨格筋細胞研究会
- Data Source
  KAKENHI-PROJECT-19K11710
[Presentation] ウェルナー症候群に合併する骨粗鬆症の臨床的特徴に関する研究2017
- Author(s)
  周赫英、森聖二郎、山賀政弥、竹本稔、小寺玲美、田村嘉章、千葉優子、荒木厚、井藤英喜、横手幸太郎
- Organizer
  第59回日本老年医学会
- Data Source
  KAKENHI-PROJECT-15K01743
[Presentation] 喫煙関連腹部大動脈瘤の遺伝子セットエンリッチメント解析2016
- Author(s)
  沢辺元司、荻島創一、周赫英、森聖二郎、田中雅嗣、三重野牧子、新井冨生、前田裕子、村松正明
- Organizer
  第58回日本老年医学会
- Place of Presentation
  石川県立音楽堂・ANAクラウンプラザホテル・金沢市アートホール (石川県金沢市)
- Year and Date
  2016-06-08
- Data Source
  KAKENHI-PROJECT-15K01743
[Presentation] GENETIC RISK SCORE BASED ON THE PREVALENCE OF VERTEBRAL FRACTURE IN JAPANESE WOMEN　WITH OSTEOPOROSIS2016
- Author(s)
  Heying Zhou, Seijiro Mori, Michiaki Kubo, Hideki Ito
- Organizer
  IOF Regionals 6th Asia-Pacific Osteoporosis Meeting (第6回アジア太平洋骨粗鬆症会議)
- Place of Presentation
  Singapore Convention & Exhibition Centre (Suntec), Singapore
- Year and Date
  2016-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01743
[Presentation] 閉経後骨粗鬆症において脊椎骨折と関連する遺伝子多型について2016
- Author(s)
  周赫英、森聖二郎、山岡巧弥、佐藤謙、坪井由紀、小寺玲美、田村嘉章、千葉優子、荒木厚、井藤英喜
- Organizer
  第58回日本老年医学会
- Place of Presentation
  石川県立音楽堂・ANAクラウンプラザホテル・金沢市アートホール (石川県金沢市)
- Year and Date
  2016-06-08
- Data Source
  KAKENHI-PROJECT-15K01743
[Presentation] Genetic risk score based on the lifetime prevalence of femoral fracture in 924 consecutive autopsies of Japanese males2015
- Author(s)
  Heying Zhou, Seijiro Mori, Tatsuro Ishizaki, Masashi Tanaka, Kumpei Tanisawa, Makiko Naka Mieno, Motoji Sawabe, Tomio Arai, Masaaki Muramatsu, Yoshiji Yamada, Hideki Ito
- Organizer
  American Society for Bone and Mineral Research's Annual Meeting
- Place of Presentation
  Seattle (USA)
- Year and Date
  2015-10-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01743
[Presentation] 連続剖検1632例の大腿骨骨折生涯罹患率に基づいた遺伝子多型リスクスコアの開発2015
- Author(s)
  周赫英, 森聖二郎, 石崎達郎, 田中雅嗣, 小寺玲美, 金原嘉之, 田村嘉章, 千葉優子, 荒木厚, 井藤英喜
- Organizer
  日本老年医学会
- Place of Presentation
  パシフィコ横浜　(神奈川県・横浜市）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-15K01743

1. Shigemoto Kazuhiro (40284400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. Shinkai shoji (60171063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 森聖二郎 (50270848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. 池本円

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 横手幸太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 竹本稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ZHOU HEYING 周 赫英

Zhou Heying 周 赫英

Research Projects

Research Products

Co-Researchers

Development of a method for the prevention and treatment of sarcopenia using high-quality cultured human muscle cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Blood concentration of postsynaptic membrane protein A reflects physical performance in aged peoplePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mesenchymal Bmp3b expression maintains skeletal muscle integrity and decreases in age-related sarcopenia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased MFG‐E8 at neuromuscular junctions is an exacerbating factor for sarcopenia‐associated denervation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reduced expression of calcitonin receptor is closely associated with age-related loss of the muscle stem cell pool.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Femoral osteoporosis is more common than lumbar osteoporosis in patients with Werner syndrome2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Implementation of personalized medicine for fracture risk assessment in osteoporosis.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic risk score based on the prevalence of vertebral fracture in Japanese women with osteoporosis2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Muscle specific aging signature of PDGFRα-positive stromal cells underlies the development of age-related sarcopenia2021

Author(s)

Organizer

Data Source

[Presentation] 様々な臓器に存在するPDGFRα陽性間質細胞の比較解析2021

Author(s)

Organizer

Data Source

[Presentation] ScxGFP iPS細胞を用いたin vitro腱・靭帯細胞分化誘導システムの確立2020

Author(s)

Organizer

Data Source

[Presentation] 神経筋結合部におけるMFG-E8の蓄積は加齢性脱神経の一因となる2020

Author(s)

Organizer

Data Source

[Presentation] PDGFRα陽性間質細胞の臓器特異性から探るサルコペニアのメカニズム2020

Author(s)

Organizer

Data Source

[Presentation] 高品質なヒト骨格筋前駆細胞の濃縮方法2020

Author(s)

Organizer

Data Source

[Presentation] カルシトニン受容体の発現低下は加齢性の骨格筋幹細胞減少に寄与する2019

Author(s)

Organizer

Data Source

[Presentation] 様々な臓器に存在するPDGFRα陽性間質細胞の比較解析2019

Author(s)

Organizer

Data Source

[Presentation] ヒト骨格筋由来前駆細胞の品質に関与する因子の同定2019

ZHOU HEYING 周赫英

Zhou Heying 周赫英

[Presentation] GENETIC RISK SCORE BASED ON THE PREVALENCE OF VERTEBRAL FRACTURE IN JAPANESE WOMEN　WITH OSTEOPOROSIS2016