OMORI TOMOKO 大森智子

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Omori Tomoko 大森智子

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Researcher Number	50754222
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 博士研究員
Affiliation (based on the past Project Information) *help	2017 – 2022: 福島県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56060:Ophthalmology-related / Ophthalmology
Keywords	Principal Investigator 補体 / 加齢黄斑変性 / 古典経路 / レクチン経路 / 免疫学

The complement lectin pathway is involved in the development of exudative age-related macular degenerationPrincipal Investigator
- Principal Investigator
  
  Omori Tomoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Fukushima Medical University
Role of complement factor MASP-1/3 in age-related macular degeneration and therapeutic effect of novel complement inhibitorsPrincipal Investigator
- Principal Investigator
  
  Omori Tomoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Fukushima Medical University

All 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] 加齢黄斑変性2022
- Author(s)
  大森智子、関根英治、石龍鉄樹
- Journal Title
  
  日本臨牀
  
  Volume: 80 Pages: 1795-1801
- Data Source
  KAKENHI-PROJECT-20K09776
[Journal Article] Age-Related Maculopathy Susceptibility 2 and Complement Factor H Polymorphism and Intraocular Complement Activation in Neovascular Age-Related Macular Degeneration2022
- Author(s)
  Yutaka Kato, Yasuharu Oguchi, Tomoko Omori, Akihito Kasai, Masashi Ogasawara, Yukinori Sugano, Kanako Itagaki, Akira Ojima, Yumi Ishida, Takeshi Machida, Hideharu Sekine, Tetsuju Sekiryu
- Journal Title
  
  Ophthalmology Science
  
  Volume: 2 Issue: 2 Pages: 100167-100167
- DOI
  10.1016/j.xops.2022.100167
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07083, KAKENHI-PROJECT-22K09795, KAKENHI-PROJECT-20K09776
[Journal Article] The complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway retains MASP-3 in the circulation2022
- Author(s)
  Kohei Kusakari, Takeshi Machida, Yumi Ishida, Tomoko Omori, Toshiyuki Suzuki, Masayuki Sekimata, Ikuo Wada, Teizo Fujita, and Hideharu Sekine
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 907023-907023
- DOI
  10.3389/fimmu.2022.907023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07083, KAKENHI-PROJECT-22K19568, KAKENHI-PROJECT-20K09776, KAKENHI-PROJECT-23K21460
[Journal Article] Changes in complement activation products after anti-VEGF injection for choroidal neovascularization in age-related macular degeneration and pachychoroid disease2021
- Author(s)
  Tanaka Keiichiro、Oguchi Yasuharu、Omori Tomoko、Ishida Yumi、Shintake Hiroaki、Tomita Ryutaro、Kasai Akihito、Ogasawara Masashi、Sugano Yukinori、Itagaki Kanako、Ojima Akira、Machida Takeshi、Sekine Hideharu、Sekiryu Tetsuju
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 8464-8464
- DOI
  10.1038/s41598-021-87340-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18882, KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-20K09776, KAKENHI-PROJECT-21K07083
[Journal Article] Evidence for Activation of Lectin and Classical Pathway Complement Components in Aqueous Humor of Neovascular Age-Related Macular Degeneration.2020
- Author(s)
  Omori T, Oguchi Y, Machida T, Kato Y, Ishida Y, Ojima A, Itagaki K, Shintake H, Tomita R, Kasai A, Sugano
- Journal Title
  
  Ophthalmic Res
  
  Volume: 63 Issue: 3 Pages: 252-258
- DOI
  10.1159/000503258
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11427, KAKENHI-PROJECT-17K16975, KAKENHI-PROJECT-18K08392
[Journal Article] Anaphylatoxin Concentration in Aqueous and Vitreous Humor in the Eyes With Vitreoretinal Interface Abnormalities2020
- Author(s)
  Yasuharu Oguchi , Tetsuju Sekiryu , Tomoko Omori , Yutaka Kato , Masashi Ogasawara , Yukinori Sugano , Kanako Itagaki , Akira Ojima , Takeshi Machida , Hideharu Sekine
- Journal Title
  
  Exp Eye Res
  
  Volume: 195 Pages: 108025-108025
- DOI
  10.1016/j.exer.2020.108025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11427, KAKENHI-PROJECT-17K16975, KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-18K08392
[Journal Article] Complement Activation Products and Cytokines in Pachychoroid Neovasculopathy and Neovascular Age-Related Macular Degeneration2020
- Author(s)
  Kato Yutaka、Oguchi Yasuharu、Omori Tomoko、Shintake Hiroaki、Tomita Ryutaro、Kasai Akihito、Ogasawara Masashi、Sugano Yukinori、Itagaki Kanako、Ojima Akira、Machida Takeshi、Sekine Hideharu、Sekiryu Tetsuju
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 61 Issue: 13 Pages: 39-39
- DOI
  10.1167/iovs.61.13.39
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-20K09776, KAKENHI-PROJECT-19K18882
[Journal Article] A novel complement inhibitor sMAP-FH targeting both the lectin and alternative complement pathways2020
- Author(s)
  Takasumi M, Omori T, Machida T, Ishida Y, Hayashi M, Suzuki T, Homma Y, Endo Y, Takahashi M, Ohira H, Fujita T, Sekine H
- Journal Title
  
  FASEB J
  
  Volume: 34 Issue: 5 Pages: 6598-6612
- DOI
  10.1096/fj.201902475r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16975, KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-18K08392
[Journal Article] Cutting Edge: Role of MASP-3 in the physiological activation of factor D of the alternative complement pathway2019
- Author(s)
  Manabu Hayashi, Takeshi Machida, Yumi Ishida, Yusuke Ogata, Tomoko Omori, Mika Takasumi, Yuichi Endo, Toshiyuki Suzuki, Masayuki Sekimata, Yoshimi Homma, Masahito Ikawa, Hiromasa Ohira, Teizo Fujita, and Hideharu Sekine
- Journal Title
  
  The Journal of Immunology
  
  Volume: 203 Issue: 6 Pages: 1411-1416
- DOI
  10.4049/jimmunol.1900605
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08392, KAKENHI-PROJECT-18K08895, KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-18K15789, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-17K16975
[Presentation] ヨウ素酸ナトリウム誘発網膜障害モデルマウスにおけるMASP-1の役割2022
- Author(s)
  大森智子、町田豪、石田由美、石龍鉄樹、関根英治
- Organizer
  第58回日本補体学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09776
[Presentation] MASP-3の活性化におけるレクチン経路の認識分子の役割2021
- Author(s)
  草刈浩平、石田由美、大森智子、鈴木俊幸、関亦正幸、町田豪、関根英治
- Organizer
  第57回日本補体学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09776
[Presentation] The significance of complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway in the long-term retention of MASP-3 in the circulation2021
- Author(s)
  Takeshi Machida, Kohei Kusakari, Yumi Ishida, Tomoko Omori, Toshiyuki Suzuki, Masayuki Sekimata, Teizo Fujita, Hideharu Sekine
- Organizer
  2021 Virtual Workshop of the International ComplementSociety
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09776
[Presentation] Complement activation product levels in aqueous humor of patients with age-related macular degeneration2019
- Author(s)
  Kato Y, Sekiryu T, Oguchi Y, Omori T, Machida T, Sekine H
- Organizer
  ARVO annual meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16975
[Presentation] 加齢黄斑変性におけるレクチン経路の関与の可能性2019
- Author(s)
  大森智子，大口泰治, 町田豪, 石田由美, 加藤寛, 石龍鉄樹, 関根英治
- Organizer
  第56回日本補体学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16975
[Presentation] 滲出型加齢黄斑変成の前房水中補体分解産物の検討2018
- Author(s)
  加藤寛、大口泰治、大森智子、町田豪、関根英治、石龍鉄樹
- Organizer
  第38回日本眼薬理学会
- Data Source
  KAKENHI-PROJECT-17K16975
[Presentation] MASP-1 and MASP-3 play independent roles in activation of the lectin and alternative complement pathways2018
- Author(s)
  Manabu Hayashi, Yumi Ishida, Takeshi Machida, Yusuke Ogata, Tomoko Omori, Mika Takasumi, Yuishi Endo, Masahiko Ikawa, Hiromasa Ohira, Teizo Fujita, Hideharu Sekine
- Organizer
  XXVII International Complement Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16975
[Presentation] MASP-1、MASP-3はレクチン経路、第二経路の活性化に独立して寄与する2018
- Author(s)
  林学、石田由美、町田豪、尾形裕介、大森智子、高住美香、遠藤雄一、関亦正幸、伊川正人、大平弘正、藤田禎三、関根英治
- Organizer
  第55回日本補体学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16975
[Presentation] 補体レクチン経路と第二経路を標的とする新規抗補体薬sMAP-fHの開発2017
- Author(s)
  高住美香、高橋実、大森智子、町田豪、石田由美、関根英治
- Organizer
  第54回日本補体学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16975

1. 石龍鉄樹 (00216540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 関根英治 (40363759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. OJIMA Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 菅野幸紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 町田豪

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
6. 笠井暁仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OMORI TOMOKO 大森 智子

Omori Tomoko 大森 智子

Research Projects

Research Products

Co-Researchers

The complement lectin pathway is involved in the development of exudative age-related macular degenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of complement factor MASP-1/3 in age-related macular degeneration and therapeutic effect of novel complement inhibitorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 加齢黄斑変性2022

Author(s)

Journal Title

Data Source

[Journal Article] Age-Related Maculopathy Susceptibility 2 and Complement Factor H Polymorphism and Intraocular Complement Activation in Neovascular Age-Related Macular Degeneration2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway retains MASP-3 in the circulation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Changes in complement activation products after anti-VEGF injection for choroidal neovascularization in age-related macular degeneration and pachychoroid disease2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evidence for Activation of Lectin and Classical Pathway Complement Components in Aqueous Humor of Neovascular Age-Related Macular Degeneration.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anaphylatoxin Concentration in Aqueous and Vitreous Humor in the Eyes With Vitreoretinal Interface Abnormalities2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Complement Activation Products and Cytokines in Pachychoroid Neovasculopathy and Neovascular Age-Related Macular Degeneration2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel complement inhibitor sMAP-FH targeting both the lectin and alternative complement pathways2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cutting Edge: Role of MASP-3 in the physiological activation of factor D of the alternative complement pathway2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] ヨウ素酸ナトリウム誘発網膜障害モデルマウスにおけるMASP-1の役割2022

Author(s)

Organizer

Data Source

[Presentation] MASP-3の活性化におけるレクチン経路の認識分子の役割2021

Author(s)

Organizer

Data Source

[Presentation] The significance of complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway in the long-term retention of MASP-3 in the circulation2021

Author(s)

Organizer

Data Source

[Presentation] Complement activation product levels in aqueous humor of patients with age-related macular degeneration2019

Author(s)

Organizer

Data Source

[Presentation] 加齢黄斑変性におけるレクチン経路の関与の可能性2019

Author(s)

Organizer

OMORI TOMOKO 大森智子

Omori Tomoko 大森智子