Naito Mitsuru 内藤瑞

… Alternative Names

NAITO MITSURU 内藤瑞

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Researcher Number	50755329
Other IDs	https://orcid.org/0000-0002-4237-871X
Affiliation (Current)	2026: 東京理科大学, 先進工学部マテリアル創成工学科, 講師
Affiliation (based on the past Project Information) *help	2024 – 2025: 東京大学, 大学院工学系研究科(工学部), 講師 2019 – 2020: 東京大学, 大学院医学系研究科(医学部), 特任助教 2018: 東京大学, 大学院医学系研究科(医学部), 特任研究員 2016: 東京大学, 大学院医学系研究科(医学部), 特任研究員 2015: 東京大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Basic Section 90120:Biomaterials-related / Medium-sized Section 90:Biomedical engineering and related fields / Biomedical engineering/Biomaterial science and engineering Except Principal Investigator Medium-sized Section 53:Organ-based internal medicine and related fields / Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator DDS / ナノマシン / 合成高分子 / DNA切断 / 遺伝子編集 / 脳腫瘍 / X線治療 / 治療 / 心筋 / 骨格筋 … More / 筋肉 / 筋ジストロフィー / 骨格筋標的 / 筋疾患 / 核酸医薬 / 薬物送達システム / 還元環境応答性 / ATP応答性 / ナノバイオ / ATP / 還元環境 / 高分子ミセル / 環境応答性 / siRNA … More Except Principal Investigator 生体適合性 / 生分解性 / 免疫原性 / ポリペプチド / 自発分解性高分子 Less

心臓を標的とした核酸医薬とシングルセル薬効評価システムの統合的開発
- Principal Investigator
  
  野村征太郎
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  The University of Tokyo
Size-tunable drug delivery systems for their application to X-ray therapy for brain tumorsPrincipal Investigator
- Principal Investigator
  
  内藤瑞
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  The University of Tokyo
自発分解性ポリペプチドの精密分子設計と免疫原性回避への挑戦
- Principal Investigator
  
  宮田完二郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Developing polymers with DNA cleavage activity for the creation of chemical gene editing toolsPrincipal Investigator
- Principal Investigator
  
  内藤瑞
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Fabrication of drug delivery systems targeting muscle tissuesPrincipal Investigator
- Principal Investigator
  
  Naito Mitsuru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  The University of Tokyo
Intracellular ATP- and redox potential-responsive siRNA delivery carrierPrincipal Investigator
- Principal Investigator
  
  NAITO MITSURU
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo

All 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Structural tuning of oligonucleotides for enhanced blood circulation properties of unit polyion complexes prepared from two-branched poly(ethylene glycol)-block-poly(l-lysine)2021
- Author(s)
  Naito Mitsuru、Chaya Hiroyuki、Toh Kazuko、Kim Beob Soo、Hayashi Kotaro、Fukushima Shigeto、Nagata Tetsuya、Yokota Takanori、Kataoka Kazunori、Miyata Kanjiro
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 330 Pages: 812-820
- DOI
  10.1016/j.jconrel.2021.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18379, KAKENHI-PROJECT-19H01016, KAKENHI-PROJECT-20H00658
[Journal Article] Photo-reactive oligodeoxynucleotide-embedded nanovesicles (PROsomes) with switchable stability for efficient cellular uptake and gene knockdown2020
- Author(s)
  Beob Soo Kim, Mitsuru Naito, Rimpei Kamegawa, Hyun Jin Kim, Ryo Iizuka, Takashi Funatsu, Shingo Ueno, Takanori Ichiki, Akihiro Kishimura, Kanjiro Miyata
- Journal Title
  
  Chem. Commun.
  
  Volume: 56 Issue: 66 Pages: 9477-9480
- DOI
  10.1039/d0cc01750g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05330, KAKENHI-PROJECT-18H03534, KAKENHI-PROJECT-18K18379
[Journal Article] Noncovalent Stabilization of Vesicular Polyion Complexes with Chemically Modified/Single-Stranded Oligonucleotides and PEG-b-guanidinylated Polypeptides for Intracavity Encapsulation of Effector Enzymes Aimed at Cooperative Gene Knockdown2020
- Author(s)
  Kim Beob Soo、Naito Mitsuru、Chaya Hiroyuki、Hori Mao、Hayashi Kotaro、Min Hyun Su、Yi Yu、Kim Hyun Jin、Nagata Tetsuya、Anraku Yasutaka、Kishimura Akihiro、Kataoka Kazunori、Miyata Kanjiro
- Journal Title
  
  Biomacromolecules
  
  Volume: 21 Issue: 10 Pages: 4365-4376
- DOI
  10.1021/acs.biomac.0c01192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03534, KAKENHI-PROJECT-18K18379
[Journal Article] Proliferation‐associated long noncoding RNA, TMPO‐AS1 , is a potential therapeutic target for triple‐negative breast cancer2020
- Author(s)
  Mitobe Yuichi、Ikeda Kazuhiro、Sato Wataru、Kodama Yukinobu、Naito Mitsuru、Gotoh Noriko、Miyata Kanjiro、Kataoka Kazunori、Sasaki Hitoshi、Horie‐Inoue Kuniko、Inoue Satoshi
- Journal Title
  
  Cancer Science
  
  Volume: 1 Issue: 7 Pages: 1-20
- DOI
  10.1111/cas.14498
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22557, KAKENHI-PROJECT-17H04205, KAKENHI-PROJECT-20K08916, KAKENHI-PROJECT-20K21636, KAKENHI-PROJECT-18H02589, KAKENHI-PROJECT-18H02679, KAKENHI-PROJECT-20H03734, KAKENHI-PROJECT-18K18379
[Journal Article] A 50-nm-Sized Micellar Assembly of Thermoresponsive Polymer-Antisense Oligonucleotide Conjugates for Enhanced Gene Knockdown in Lung Cancer by Intratracheal Administration.2020
- Author(s)
  B. S. Kim, S. Osawa, M. Naito, S. Ogura, R. Kamegawa, H. Ishida, H. J. Kim, S. Uchida, K. Miyata
- Journal Title
  
  Advanced Therapeutics
  
  Volume: 3 Issue: 2 Pages: 1900123-1900123
- DOI
  10.1002/adtp.201900123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-18K18379
[Journal Article] Installation of a Thermoswitchable Hydrophobic Domain into a Unimer Polyion Complex for Enhanced Cellular Uptake of siRNA2020
- Author(s)
  Kim Beob Soo、Osawa Shigehito、Yum Jongmin、Naito Mitsuru、Miyata Kanjiro
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 31 Issue: 5 Pages: 1320-1326
- DOI
  10.1021/acs.bioconjchem.0c00238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18392, KAKENHI-PROJECT-18K18379
[Journal Article] Systemic Brain Delivery of Antisense Oligonucleotides across the Blood-Brain Barrier with a Glucose-Coated Polymeric Nanocarrier2020
- Author(s)
  Min Hyun Su、Kim Hyun Jin、Naito Mitsuru、Ogura Satomi、Toh Kazuko、Hayashi Kotaro、Kim Beob Soo、Fukushima Shigeto、Anraku Yasutaka、Miyata Kanjiro、Kataoka Kazunori
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 59 Issue: 21 Pages: 8173-8180
- DOI
  10.1002/anie.201914751
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K18379
[Journal Article] Bundling mRNA strands to prepare nano-assemblies with enhanced stability towards RNase for in vivo delivery.2019
- Author(s)
  N. Yoshinaga, E. Cho, K. Koji, Y. Mochida, M. Naito, K. Osada, K. Kataoka, H. Cabral, S. Uchida
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 58 Issue: 33 Pages: 11360-11363
- DOI
  10.1002/anie.201905203
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-18K19901, KAKENHI-PROJECT-18K18379
[Journal Article] Tunable non-enzymatic degradability of N-substituted polyaspartamide main chain by amine protonation and alkyl spacer length in side chains for enhanced messenger RNA transfection efficiency.2019
- Author(s)
  M. Naito, Y. Otsu, R. Kamegawa, K. Hayashi, S. Uchida, H. -J. Kim, K. Miyata
- Journal Title
  
  Sci. Technol. Adv. Mater.
  
  Volume: 20 Issue: 1 Pages: 105-115
- DOI
  10.1080/14686996.2019.1569818
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-18K18379
[Journal Article] Glucose-linked sub-50-nm unimer polyion complex-assembled gold nanoparticles for targeted siRNA delivery to glucose transporter 1-overexpressing breast cancer stem-like cells.2019
- Author(s)
  Y. Yi, H. J. Kim, M. Zheng, P. Mi, M. Naito, B. S. Kim, H. S. Min, K. Hayashi, F. Perche, K. Toh, X. Liu, Y. Mochida, H. Kinoh, H. Cabral, K. Miyata, K. Kataoka
- Journal Title
  
  J. Control. Release
  
  Volume: 295 Pages: 268-277
- DOI
  10.1016/j.jconrel.2019.01.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07234, KAKENHI-PROJECT-18K18378, KAKENHI-PROJECT-17H02098, KAKENHI-PROJECT-18H04170, KAKENHI-PROJECT-20K20386, KAKENHI-PROJECT-18K18391, KAKENHI-PROJECT-18K18379
[Journal Article] Dually stabilized triblock copolymer micelles with hydrophilic shell and hydrophobic interlayer for systemic antisense oligonucleotide delivery to solid tumor2019
- Author(s)
  Beob Soo Kim, Hyun Jin Kim, Shigeto Osawa, Kotaro Hayashi, Kazuko Toh, Mitsuru Naito, Hyun Su Min, Yu Yi, Ick Chan Kwon, Kazunori Kataoka, Kanjiro Miyata
- Journal Title
  
  ACS Biomaterials Science & Engineering
  
  Volume: 5 Issue: 11 Pages: 5770-5780
- DOI
  10.1021/acsbiomaterials.9b00384
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18391, KAKENHI-PROJECT-18K18379
[Journal Article] Induced packaging of mRNA into polyplex micelles by regulated hybridization with a small number of cholesteryl RNA oligonucleotides directed enhanced in vivo transfection.2019
- Author(s)
  N. Yoshinaga, S. Uchida, M. Naito, K. Osada, H. Cabral, K. Kataoka
- Journal Title
  
  Biomaterials
  
  Volume: 197 Pages: 255-267
- DOI
  10.1016/j.biomaterials.2019.01.023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K20086, KAKENHI-PROJECT-17KK0102, KAKENHI-PROJECT-16H03178, KAKENHI-PROJECT-16H03179, KAKENHI-PROJECT-18H03529, KAKENHI-PROJECT-18K19901, KAKENHI-PROJECT-20K20386, KAKENHI-PROJECT-18J14336, KAKENHI-PROJECT-18K18379
[Journal Article] Tuned Density of Anti-Tissue Factor Antibody Fragment onto siRNA-Loaded Polyion Complex Micelles for Optimizing Targetability into Pancreatic Cancer Cells2018
- Author(s)
  Min Hyun Su、Kim Hyun Jin、Ahn Jooyeon、Naito Mitsuru、Hayashi Kotaro、Toh Kazuko、Kim Beob Soo、Matsumura Yasuhiro、Kwon Ick Chan、Miyata Kanjiro、Kataoka Kazunori
- Journal Title
  
  Biomacromolecules
  
  Volume: 19 Issue: 6 Pages: 2320-2329
- DOI
  10.1021/acs.biomac.8b00507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H04170, KAKENHI-PROJECT-18K18379
[Presentation] 核酸を用いた安定的DDSによる血行再建後内膜肥厚抑制の試み2021
- Author(s)
  佐野允哉, 赤木大輔, 内藤瑞, 遠藤貴士, 露木翔太, 前野竜平, 大片慎也, 花田和正, 大橋雄一, 福原菜摘, 宮原和洋, 赤井隆文, 松倉満, 伊佐治寿彦, 高山利夫, 宮田完二郎, 保科克行
- Organizer
  第51回日本心臓血管外科学会総会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] アンチセンス核酸送達に向けた機能性核酸型ベシクルの開発2021
- Author(s)
  岸村顕広, Beob Soo KIM, 内藤瑞, 茶谷洋行, 林光太朗, Hyun Jin KIM, 片岡一則, 宮田完二郎
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 高分子材料及び核酸化学構造の精密設計に基づく極小核酸送達システムの構築と難治がん治療応用への展開2021
- Author(s)
  茶谷洋行, 渡邉秀美代, 林光太朗, 藤加珠子, キムヒョンジン,　内藤瑞, キムボブス, 片岡一則, 宮田完二郎
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 核酸を用いた安定的DDSによる血行再建後内膜肥厚抑制の試み2021
- Author(s)
  佐野允哉, 赤木大輔, 内藤瑞, 遠藤貴士, 露木翔太, 前野竜平, 大片慎也, 花田和正, 大橋雄一, 福原菜摘, 宮原和洋, 赤井隆文, 松倉満, 伊佐治寿彦, 高山利夫, 宮田完二郎, 保科克行
- Organizer
  第121回日本血管外科学会総会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 核酸を用いた安定的DDSによる血行再建後内膜肥厚抑制の試み2020
- Author(s)
  佐野允哉, 赤木大輔, 内藤瑞, 遠藤貴士, 露木翔太, 前野竜平, 大片慎也, 花田和正, 大橋雄一, 福原菜摘, 宮原和洋, 赤井隆文, 松倉満, 伊佐治寿彦, 高山利夫, 宮田完二郎, 保科克行
- Organizer
  第61回日本脈管学会総会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 動的結合点をもつ高分子ゲルからのナノ粒子の徐放性評価2020
- Author(s)
  HOGREL Adrien、内藤瑞、亀川凜平、片島拓弥、KIM HyunJin、松元亮、宮田完二郎
- Organizer
  第31回高分子ゲル研究討論会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 核酸を用いた安定的DDSによる血行再建後内膜肥厚抑制の試み2020
- Author(s)
  佐野允哉, 赤木大輔, 内藤瑞, 遠藤貴士, 露木翔太, 前野竜平, 大片慎也, 花田和正, 大橋雄一, 福原菜摘, 宮原和洋, 赤井隆文, 松倉満, 伊佐治寿彦, 高山利夫, 宮田完二郎, 保科克行
- Organizer
  第48回日本血管外科学会総会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] mRNAデリバリーのためのpolyaspartamide誘導体の開発とCRISPR-Casテクノロジーへの応用2020
- Author(s)
  キムヒョンジン, 小倉里美, ヨムジョンミン, 内藤瑞, 宮田完二郎
- Organizer
  第69回高分子討論会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] がん細胞表面のシアル酸を標的としたピリジルボロン酸含有ポリマー型リガンドの設計と機能評価2020
- Author(s)
  宮島健，内藤瑞，松元亮，宮原裕二，宮田完二郎
- Organizer
  第69回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 熱処理法によるポリエチレングリコール被覆リン酸カルシウムナノ粒子の構造安定化2020
- Author(s)
  大野泰宗, 亀川凜平, 内藤瑞, 宮田完二郎
- Organizer
  第36回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 核酸を用いた安定的DDSによる血行再建後内膜肥厚抑制の試み2020
- Author(s)
  佐野允哉, 赤木大輔, 内藤瑞, 大片慎也, 花田和正, 大橋雄一, 福原菜摘, 宮原和洋, 赤井隆文, 松倉満, 伊佐治寿彦, 高山利夫, 宮田完二郎, 保科克行
- Organizer
  第120回日本外科学会総会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] フェニルボロン酸を含有するナノ粒子の創製とATPセンサーへの応用2020
- Author(s)
  高橋のどか, 内藤瑞, 宮田完二郎
- Organizer
  第69回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 細胞治療に資する核酸デリバリー2020
- Author(s)
  宮田完二郎, 内藤瑞, キムヒョンジン
- Organizer
  第36回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 酵素非依存的な分解性を有するカチオン性ポリアスパラギン酸の構造とmRNA送達への応用2020
- Author(s)
  大津祐太，内藤瑞，亀川凜平，林光太朗，内田智士，キムヒョンジン，宮田完二郎
- Organizer
  第69回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] Cas9 mRNAの局所送達による効率的な遺伝子編集のためのカチオン性両親媒性ポリマーの開発2020
- Author(s)
  キムヒョンジン, 小倉里美, ヨムジョンミン, 内藤瑞, 宮田完二郎
- Organizer
  第69回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] Silica-coated polyion complexes as messenger RNA carrier for oral delivery to the intestine2020
- Author(s)
  R. Kamegawa, M. Naito, S. Uchida, H. J. Kim, B. S. Kim, K. Miyata
- Organizer
  16th Annual Meeting of the Oligonucleotide Therapeutics Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] アンチセンス核酸送達を通じて考えるポリイオンコンプレックス材料の設計戦略2020
- Author(s)
  岸村顕広, Kim Beob Soo, 内藤瑞, 茶谷洋行, 林光太朗, Kim Hyun Jin, 片岡一則, 宮田完二郎
- Organizer
  第69回高分子討論会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] フェニルボロン酸エステルによる動的架橋ハイドロゲルの構築と内包物質の放出性能評価2020
- Author(s)
  亀川凜平, ホグレルアドリアン, 内藤瑞, キムボブス, キムヒョンジン, 片島拓弥, 酒井崇匡, 松元亮, 宮田完二郎
- Organizer
  第69回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 1分子核酸内包キャリアの血中滞留性向上を指向した核酸医薬の精密構造設計2020
- Author(s)
  茶谷洋行, 内藤瑞, 藤加珠子, キムボブス, 林光太朗, 福島重人, 片岡一則, 宮田完二郎
- Organizer
  第15回ナノ・バイオメディカル学会大会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] グラフトポリマー型ナノキャリアの設計と固形がんへの集積性に対するサイズ効果の検討2020
- Author(s)
  J. Yum, 内藤瑞, H. J. Kim, 宮田完二郎
- Organizer
  第69回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 細胞内ATP応答性siRNA内包高分子ミセルの開発2020
- Author(s)
  内藤瑞, 吉永直人, 石井武彦, 松元亮, 宮田完二郎, 片岡一則
- Organizer
  第69回高分子討論会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 異なるシロキサン結合密度を有するシリカ被覆ポリイオンコンプレックスの構築と経口メッセンジャーRNAデリバリーへの展開2020
- Author(s)
  亀川凜平, 内藤瑞, 内田智士, Kim Hyun Jin, Kim Beob Soo, 宮田完二郎
- Organizer
  第36回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] オリゴ核酸を膜成分として含有するベシクル型ポリイオンコンプレックスの構築と機能評価2020
- Author(s)
  宮田完二郎, キムボブス, 内藤瑞, キムヒョンジン, 片岡一則, 岸村顕広
- Organizer
  第69回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] ATP-responsive polyion complex micelles for intracellular delivery of siRNA and pDNA2019
- Author(s)
  Mitsuru Naito, Naoto Yoshinaga, Takehiko Ishii, Akira Matsumoto, Kazunori Kataoka, Kanjiro Miyata
- Organizer
  The 15th US-Japan Symposium on Drug Delivery Systems
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] ピリジルボロン酸とがん細胞表面のシアル酸との特異的な結合を利用したポリマー型リガンドの開発2019
- Author(s)
  宮島健、内藤瑞、松元亮、宮原裕二、宮田完二郎
- Organizer
  第41回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] Responsivity of siRNA-loaded phenylboronate-functionalized polyion complex (PIC) micelles against biomolecules2019
- Author(s)
  Mitsuru Naito, Yuta Otsu, Rimpei Kamegawa, Kotaro Hayashi, Satoshi Uchida, Hyun Jin Kim, Kanjiro Miyata
- Organizer
  Materials Research Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] Tunable non-enzymatic degradable N-substituted polyaspartamide for enhanced mRNA delivery2019
- Author(s)
  Mitsuru Naito, Yuta Otsu, Rimpei Kamegawa, Kotaro Hayashi, Satoshi Uchida, Hyun Jin Kim, Kanjiro Miyata
- Organizer
  19th Symposium for Gene Design and Delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 化学修飾核酸を内包したPICミセルの血中安定性評価2019
- Author(s)
  内藤瑞、茶谷洋行、Kim BeobSoo、藤加珠子、宮田完二郎
- Organizer
  日本核酸医薬学会第5回年会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] Non-enzymatically degradable poly(amino acid) derivatives for mRNA delivery2019
- Author(s)
  Mitsuru Naito, Yuta Otsu, Rimpei Kamegawa, Kotaro Hayashi, Satoshi Uchida, Hyun Jin Kim, Kanjiro Miyata
- Organizer
  European Polymer Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] ATP応答性高分子ミセルによる細胞質内へのsiRNAデリバリー技術の開発2018
- Author(s)
  内藤　瑞、吉永　直人、石井　武彦、松元　亮、宮原　裕二、宮田　完二郎、片岡　一則
- Organizer
  第67回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 細胞内へのsiRNA送達を目指したATP応答性高分子ミセルの開発2018
- Author(s)
  内藤　瑞、吉永　直人、松元　亮、宮原　裕二、宮田　完二郎、片岡　一則
- Organizer
  第13回ナノバイオ・メディカル学会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 細胞質内へのsiRNA送達を目指したATP応答性高分子ミセルの開発2018
- Author(s)
  内藤　瑞、吉永　直人、石井　武彦、松元　亮、宮原　裕二、宮田　完二郎、片岡　一則
- Organizer
  日本核酸医薬学会　第４回年会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] Fabrication of Intracellular ATP-responsive plyion complex micelles for smart nucleotide therapeutics delivery2018
- Author(s)
  Mitsuru Naito、Naoto Yoshinaga, Akira Matsumoto, Yuji Miyahara, Kanjiro Miyata, Kazunori Kataoka
- Organizer
  2018 Fall Meeting of the korean society for Bioaterials
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] Fabrication of intracellular ATP-responsive polyion complex micelles2018
- Author(s)
  内藤　瑞、吉永　直人、石井　武彦、松元　亮、宮原　裕二、宮田　完二郎、片岡　一則
- Organizer
  第40回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-18K18379
[Presentation] 細胞内へのsiRNA送達を目指したATP応答性PICミセルの機能評価2017
- Author(s)
  内藤瑞
- Organizer
  第66回高分子学会年次大会
- Place of Presentation
  幕張メッセ (千葉県千葉市)
- Year and Date
  2017-05-29
- Data Source
  KAKENHI-PROJECT-15H06108
[Presentation] ATP-responsive polyion complex micelles for intracellular delivery of siRNA2016
- Author(s)
  内藤瑞
- Organizer
  3rd International Conference on Biomaterials Science in Tokyo
- Place of Presentation
  東京大学 (東京都文京区)
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06108

1. 持田祐希 (60739134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 吉岡耕太郎 (70780641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 田村郁 (70629146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 中村乃理子 (80910174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 宮田完二郎 (50436523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 森健 (70335785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 野村征太郎 (10722118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KISHIMURA Akihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 飯塚怜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 片岡一則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 内田智士

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
12. 後藤典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 大澤重仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 喜納宏昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 劉学瑩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 林光太朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Naito Mitsuru 内藤 瑞

NAITO MITSURU 内藤 瑞

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心臓を標的とした核酸医薬とシングルセル薬効評価システムの統合的開発

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Size-tunable drug delivery systems for their application to X-ray therapy for brain tumorsPrincipal Investigator

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自発分解性ポリペプチドの精密分子設計と免疫原性回避への挑戦

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Developing polymers with DNA cleavage activity for the creation of chemical gene editing toolsPrincipal Investigator

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Fabrication of drug delivery systems targeting muscle tissuesPrincipal Investigator

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Intracellular ATP- and redox potential-responsive siRNA delivery carrierPrincipal Investigator

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[Journal Article] Structural tuning of oligonucleotides for enhanced blood circulation properties of unit polyion complexes prepared from two-branched poly(ethylene glycol)-block-poly(l-lysine)2021

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[Journal Article] Photo-reactive oligodeoxynucleotide-embedded nanovesicles (PROsomes) with switchable stability for efficient cellular uptake and gene knockdown2020

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[Journal Article] Noncovalent Stabilization of Vesicular Polyion Complexes with Chemically Modified/Single-Stranded Oligonucleotides and PEG-b-guanidinylated Polypeptides for Intracavity Encapsulation of Effector Enzymes Aimed at Cooperative Gene Knockdown2020

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[Journal Article] Proliferation‐associated long noncoding RNA, TMPO‐AS1 , is a potential therapeutic target for triple‐negative breast cancer2020

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[Journal Article] A 50-nm-Sized Micellar Assembly of Thermoresponsive Polymer-Antisense Oligonucleotide Conjugates for Enhanced Gene Knockdown in Lung Cancer by Intratracheal Administration.2020

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[Journal Article] Installation of a Thermoswitchable Hydrophobic Domain into a Unimer Polyion Complex for Enhanced Cellular Uptake of siRNA2020

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[Journal Article] Systemic Brain Delivery of Antisense Oligonucleotides across the Blood-Brain Barrier with a Glucose-Coated Polymeric Nanocarrier2020

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[Journal Article] Bundling mRNA strands to prepare nano-assemblies with enhanced stability towards RNase for in vivo delivery.2019

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Naito Mitsuru 内藤瑞

NAITO MITSURU 内藤瑞