Shiba Yoko 芝陽子

… Alternative Names

芝陽子シバヨウコ

shiba yoko 芝陽子

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Researcher Number	50755866
Other IDs
Affiliation (Current)	2026: 岩手大学, 理工学部, 准教授
Affiliation (based on the past Project Information) *help	2026: 岩手大学, 理工学部, 准教授 2023 – 2024: 岩手大学, 理工学部, 准教授 2019 – 2021: 岩手大学, 理工学部, 准教授 2016: 岩手大学, 理工学部, 准教授 2015: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Basic Section 44010:Cell biology-related / Cell biology
Keywords	Principal Investigator Arf / 分泌顆粒 / WPB / vWF / ArfGAP / 分泌 / 膜輸送 / 止血 / 血管内皮細胞 / 分解 … More / MVB / エクソソーム / 細胞内輸送 / 出荷審査 / HUVEC / コートタンパク質 / 輸送小胞 / 選別 / AGFG2 / SMAP1 / 阻害剤 / 小胞体ストレスセンサー / IRE1a / 小胞体ストレス / IRE1alpha / インスリン Less

CD63陽性の分泌性MVB形成におけるArfGAPファミリー、ARAP1とADAP1の機能解析Principal Investigator
- Principal Investigator
  
  芝陽子
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Iwate University
止血因子を貯留する分泌顆粒WPBの分解機構の解明：出荷審査は行われているのか？Principal Investigator
- Principal Investigator
  
  芝陽子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Iwate University
Do GTPase activating protein ArfGAPs perform "shipping inspection"?Principal Investigator
- Principal Investigator
  
  shiba yoko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Iwate University
Determine the molecular mechanisms by which IRE1a, an ER stress sensor plays a role in insulin secretionPrincipal Investigator
- Principal Investigator
  
  Shiba Yoko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Cell biology
- Research Institution
  Iwate University
  Nara Institute of Science and Technology

All 2025 2024 2023 2021 2020 2019 2017 2016

All Journal Article Presentation

[Journal Article] ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation2025
- Author(s)
  S Poddar et al, 24/33, Y shiba, and Jonathan Miner
- Journal Title
  
  Cell
  
  Volume: 188 Issue: 6 Pages: 1605-1622.e26
- DOI
  10.1016/j.cell.2025.01.027
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05676
[Journal Article] Magnetic control of membrane damage in early endosomes using internalized magnetic nanoparticles2025
- Author(s)
  Yonekawa Yuta、Oikawa Kazuki、Bayarkhuu Boldbaatar、Kobayashi Kizuna、Saito Nana、Oikawa Ibuki、Yamada Ryohei、Chen Yu-han、Oyanagi Koichi、Shibasaki Yuji、Kobayashi Satoru、Shiba Yoko
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 50 Issue: 1 Pages: 25-39
- DOI
  10.1247/csf.24037
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05676
[Journal Article] Arf GTPase-Activating proteins ADAP1 and ARAP1 regulate incorporation of CD63 in multivesicular bodies2024
- Author(s)
  Suzuki Kasumi、Okawa Yoshitaka、Akter Sharmin、Ito Haruki、Shiba Yoko
- Journal Title
  
  Biology Open
  
  Volume: 13 Issue: 5 Pages: 1-12
- DOI
  10.1242/bio.060338
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05676
[Journal Article] Arf GTPase-activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor2021
- Author(s)
  Asano Watanabe, Hikari Hataida, Naoya Inoue, Kosuke Kamon, Keigo Baba, Kuniaki Sasaki, Rika Kimura, Honoka Sasaki, Yuka Eura, Wei-Fen Ni, Yuji Shibasaki, Satoshi Waguri, Koichi Kokame and Yoko Shiba
- Journal Title
  
  Biology open
  
  Volume: 10 Issue: 9
- DOI
  10.1242/bio.058789
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06557, KAKENHI-PROJECT-20H03415
[Journal Article] Arf GTPase-Activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor2021
- Author(s)
  Asano Watanabe, Hikari Hataida, Naoya Inoue, Kosuke Kamon, Keigo Baba, Kuniaki Sasaki, Rika Kimura, Honoka Sasaki, Yuka Eura, Wei-Fen Ni, Yuji Shibasaki, Satoshi Waguri, Koichi Kokame, Yoko Shiba
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2021.03.29.437631
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06557
[Journal Article] Enhanced antimicrobial activities of polymerized arbutin and its derivatives prepared by oxidative polymerization of arbutin2019
- Author(s)
  Kajiwara Rika、Seto Ayaka、Kofujita Hisayoshi、Shiba Yoko、Oishi Yoshiyuki、Shibasaki Yuji
- Journal Title
  
  Reactive and Functional Polymers
  
  Volume: 138 Pages: 39-45
- DOI
  10.1016/j.reactfunctpolym.2019.02.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05211, KAKENHI-PROJECT-19K06557
[Journal Article] 4μ8C inhibits insulin secretion independent of IRE1α RNase activity2017
- Author(s)
  Hitomi Sato, Yoko Shiba, Yuichi Tsuchiya, Michiko Saito, and Kenji Kohno
- Journal Title
  
  Cell Structure and Function
  
  Volume: 印刷中
- NAID
  130005635485
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06410
[Presentation] 磁性ナノ粒子を用いたエンドソーム膜の損傷評価2024
- Author(s)
  米川悠太、BOLDBAATAR BAYARKHUU、及川一貴,及川歩起、山田凌平、西館直樹、西條未来、大柳洸一、小林悟、芝﨑祐二、芝陽子
- Organizer
  第７６回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-23K05676
[Presentation] Arf GTPase-Activating proteins ADAP1 and ARAP1 regulate incorporation of CD63 in multivesicular bodies.2024
- Author(s)
  Sharmin Akter, Kasumi Suzuki, Yoshitaka Okawa, Haruki Ito , Yoko Shiba
- Organizer
  第７６回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-23K05676
[Presentation] オレイン酸被覆磁性体ナノ粒子の簡便な水溶性化とグリセリンポリマーによる被覆2024
- Author(s)
  川村綾音，及川歩起，Boldbaatar Bayarkhuu，米川悠太，及川一貴，小林悟，大柳洸一，芝陽子，芝崎祐二,
- Organizer
  第40回DDS学会
- Data Source
  KAKENHI-PROJECT-23K05676
[Presentation] ArfGTPase activating protein（ArfGAPs）、ADAP1 とARAP1はCD63 のMVBs への局在に関与する。2024
- Author(s)
  芝陽子、鈴木花純、アクターシャーミン、大川義敬
- Organizer
  第11回日本細胞外小胞学会
- Data Source
  KAKENHI-PROJECT-23K05676
[Presentation] Determine the role of SMAP1 in WPB degradation in endotheial cells2023
- Author(s)
  Dai Yaegashi, Sasayama Sousuke, Nana Saito, Kosuke Kamon and Yoko Shiba
- Organizer
  第７５回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-23K05676
[Presentation] vWFの細胞内輸送に関与する新規ArfGAPファミリータンパク質の機能解析2021
- Author(s)
  芝　陽子
- Organizer
  第43回日本血栓止血学会
- Data Source
  KAKENHI-PROJECT-19K06557
[Presentation] von Willebrand Factorの細胞内輸送におけるArfGAPの機能の解明2021
- Author(s)
  馬場圭吾, 芝陽子
- Organizer
  第73回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-19K06557
[Presentation] How do ArfGAPs regulate cargo sorting?2020
- Author(s)
  Yoko Shiba
- Organizer
  第７２回日本細胞生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06557
[Presentation] Identification of ArfGAPs involved in formation of Weibel-Palade Bodies2020
- Author(s)
  Kosuke Kamon, Keigo Baba, Asano Watanabe , Hikari Hataida , Naoya Inoue, Rika Kimura, Honoka Sasaki, Kuniaki Sasaki, Yuka Higuchi, Koichi Kokame, Yoko Shiba
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K06557
[Presentation] ArfGAPs regulate the formation of secretory granules of von Willebrand factor2019
- Author(s)
  Hataida H, Watanabe A, Sasaki K. and ○Shiba Y
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Data Source
  KAKENHI-PROJECT-19K06557
[Presentation] ArfGAPs regulate the formation of secretory granules of von Willebrand Factor2019
- Author(s)
  芝　陽子
- Organizer
  第４３回峠の会
- Data Source
  KAKENHI-PROJECT-19K06557
[Presentation] vWF分泌顆粒形成に関与するArfGAPの同定2019
- Author(s)
  Asano Watanabe, Hikari Hataida, 〇Naoya Inoue, Rika Kimura, Honoka Sasaki, Kuniaki Sasaki, Senri Ushida, Eiji Morita, Yoko Shiba
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K06557
[Presentation] 膵島β細胞における阻害剤をもちいたIRE1αの機能解析2017
- Author(s)
  佐藤仁美、芝陽子、土屋雄一、斉藤美知子、河野憲二
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15H06410
[Presentation] 膵島β細胞のインスリン産生におけるIRE1αの機能解析2016
- Author(s)
  Hitomi Sato, Yoko Shiba, Yuichi Tsuchiya, Michiko Saito and Kenji Kohno
- Organizer
  第10回小胞体ストレス研究会
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2016-11-29
- Data Source
  KAKENHI-PROJECT-15H06410

1. 芝崎祐二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shiba Yoko 芝 陽子

芝 陽子 シバ ヨウコ

shiba yoko 芝 陽子

Research Projects

Research Products

Co-Researchers

CD63陽性の分泌性MVB形成におけるArfGAPファミリー、ARAP1とADAP1の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

止血因子を貯留する分泌顆粒WPBの分解機構の解明：出荷審査は行われているのか？Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Do GTPase activating protein ArfGAPs perform "shipping inspection"?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Determine the molecular mechanisms by which IRE1a, an ER stress sensor plays a role in insulin secretionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Magnetic control of membrane damage in early endosomes using internalized magnetic nanoparticles2025

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Arf GTPase-Activating proteins ADAP1 and ARAP1 regulate incorporation of CD63 in multivesicular bodies2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Arf GTPase-activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Arf GTPase-Activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhanced antimicrobial activities of polymerized arbutin and its derivatives prepared by oxidative polymerization of arbutin2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 4μ8C inhibits insulin secretion independent of IRE1α RNase activity2017

Author(s)

Journal Title

NAID

Data Source

[Presentation] 磁性ナノ粒子を用いたエンドソーム膜の損傷評価2024

Author(s)

Organizer

Data Source

[Presentation] Arf GTPase-Activating proteins ADAP1 and ARAP1 regulate incorporation of CD63 in multivesicular bodies.2024

Author(s)

Organizer

Data Source

[Presentation] オレイン酸被覆磁性体ナノ粒子の簡便な水溶性化とグリセリンポリマーによる被覆2024

Author(s)

Organizer

Data Source

[Presentation] ArfGTPase activating protein（ArfGAPs）、ADAP1 とARAP1はCD63 のMVBs への局在に関与する。2024

Shiba Yoko 芝陽子

芝陽子シバヨウコ

shiba yoko 芝陽子

[Presentation] vWFの細胞内輸送に関与する新規ArfGAPファミリータンパク質の機能解析2021