Nakasone Hideki 仲宗根秀樹

… Alternative Names

NAKASONE Hideki 仲宗根秀樹

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Researcher Number	50757903
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 自治医科大学, 医学部, 教授 2022 – 2023: 自治医科大学, 医学部, 教授 2021 – 2022: 自治医科大学, 医学部, 准教授 2015 – 2020: 自治医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 54030:Infectious disease medicine-related / Basic Section 49070:Immunology-related / Hematology Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Tumor therapeutics
Keywords	Principal Investigator バイオマーカー / 薬物療法 / T細胞療法 / HTLV-1 / 移植片対宿主病 / キメリズム / 同種抗原特異的B細胞 / 臨床アウトカム / 同種免疫 / マイナー抗原 … More / 性別不一致 / HY免疫 / 性別不一致移植 / 造血幹細胞移植学 / NAMPT/visaftin / 皮膚線維芽細胞 / アディポネクチン / 造血幹細胞移植 / サイトカイン / アディポカイン / 慢性移植片対宿主病 … More Except Principal Investigator 成人T細胞性白血病 / Tax / 免疫細胞療法 / 遺伝子治療 / 遺伝子導入細胞療法 / 遺伝子導入 / HTLV-1 / 成人T細胞性白血病リンパ腫 / 腫瘍免疫 / 成人T 細胞白血病・リンパ腫 / 細胞免疫療法 / 免疫学 / 腫瘍特異的免疫細胞療法 / 遺伝子導入免疫細胞療法 Less

相乗的なHTLV-1増殖制御戦略に向けた免疫回避機序への介入とウイルス特異的T細胞療法Principal Investigator
- Principal Investigator
  
  仲宗根秀樹
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Jichi Medical University
成人T細胞白血病リンパ腫に対する遺伝子導入細胞療法の至適化
- Principal Investigator
  
  神田善伸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Jichi Medical University
Sex-mismatched hematopoietic cell transplantation and acquisition of B-cells specific to antigens on Y-chromosomePrincipal Investigator
- Principal Investigator
  
  Nakasone Hideki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Jichi Medical University
Preclinical research for the clinical application of T-cell receptor gene therapy targeting tax for adult T-cell leukemia/lymphoma
- Principal Investigator
  
  Kanda Yoshinobu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Jichi Medical University
A role of adipokine/related protein in chronic graft-versus-host disease after allogeneic hematopoietic cell transplantationPrincipal Investigator
- Principal Investigator
  
  NAKASONE Hideki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Investigation of redirected Tax-specific T-cell immunotherapy against adult T-cell leukemia/lymphoma
- Principal Investigator
  
  KANDA YOSHINOBU
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Jichi Medical University

All 2023 2022 2020 2019 2017 2016

All Journal Article Presentation Patent

[Journal Article] Plasma ubiquitin C-terminal hydrolase-L1 (UCH-L1) level as a blood biomarker of neurological damage after allogeneic hematopoietic cell transplantation2023
- Author(s)
  Okada Yosuke、Nakasone Hideki、Yoshimura Kazuki、Tamaki Masaharu、Kusuda Machiko、Nakamura Yuhei、Kawamura Masakatsu、Kawamura Shunto、Takeshita Junko、Yoshino Nozomu、Misaki Yukiko、Gomyo Ayumi、Tanihara Aki、Kimura Shun-ichi、Kako Shinichi、Kanda Yoshinobu
- Journal Title
  
  International Journal of Hematology
  
  Volume: 118 Issue: 3 Pages: 340-346
- DOI
  10.1007/s12185-023-03642-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08463
[Journal Article] Impact of anti-thymocyte globulin on survival outcomes in female-to-male allogeneic hematopoietic stem cell transplantation2023
- Author(s)
  Tamaki Masaharu、Akahoshi Yu、Ashizawa Masahiro、Misaki Yukiko、Koi Satoshi、Kim Sung-Won、Ozawa Yukiyasu、Fujiwara Shin-ichiro、Kako Shinichi、Matsuoka Ken-ichi、Sawa Masashi、Katayama Yuta、Onizuka Makoto、Kanda Yoshinobu、Fukuda Takahiro、Atsuta Yoshiko、Yakushijin Kimikazu、Nakasone Hideki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1
- DOI
  10.1038/s41598-023-34442-y
- Data Source
  KAKENHI-PROJECT-21K07070
[Journal Article] Antibody-mediated pathogenesis of chronic GVHD through DBY/HLA class II complexes and induction of a GVL effect.2023
- Author(s)
  Umino K, Morita K, Ikeda T, Kawaguchi SI, Nagayama T, Ito S, Minakata D, Ashizawa M, Yamamoto C, Hatano K, Sato K, Ohmine K, Fujiwara SI, Kimura SI, Kako S, Doki N, Ozawa Y, Mori Y, Eto T, Hiramoto N, Nakamae H, Kanda J, Ichinohe T, Atsuta Y, Nakasone H, Morishima S, Kanda Y.
- Journal Title
  
  Blood.
  
  Volume: 142 Issue: 11 Pages: 1008-1021
- DOI
  10.1182/blood.2023019799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08737, KAKENHI-PROJECT-22K08463, KAKENHI-PROJECT-23K07863, KAKENHI-PROJECT-22K16309
[Journal Article] Gene expression and <scp>TCR</scp> amino acid sequences selected by <scp>HLA‐A02</scp>:01‐restricted <scp>CTLs</scp> specific to <scp>HTLV</scp>‐1 in <scp>ATL</scp> patients2023
- Author(s)
  Kusuda Machiko、Nakasone Hideki、Yoshimura Kazuki、Okada Yosuke、Tamaki Masaharu、Matsuoka Akari、Ishikawa Takuto、Meno Tomohiro、Nakamura Yuhei、Kawamura Masakatsu、Takeshita Junko、Kawamura Shunto、Yoshino Nozomu、Misaki Yukiko、Gomyo Ayumi、Tanihara Aki、Kimura Shun‐ichi、Kako Shinichi、Kanda Yoshinobu
- Journal Title
  
  British Journal of Haematology
  
  Volume: 202 Issue: 3 Pages: 578-588
- DOI
  10.1111/bjh.18918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08463
[Journal Article] Unrelated female-to-male bone marrow transplantation would be preferred over cord blood transplantation in male patients2023
- Author(s)
  Tamaki M, Akahoshi Y, Okada Y, Uchida N, Tanaka M, Doki N, Sawa M, Maruyama Y, Ueda Y, Miyakoshi S, Katayama Y, Kawakita T, Kimura T, Onizuka M, Fukuda T, Atsuta Y, Yanagisawa R, Yakushijin K, Kanda J, Nakasone H.
- Journal Title
  
  Cytotherapy
  
  Volume: 25 Issue: 11 Pages: 1220-1228
- DOI
  10.1016/j.jcyt.2023.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07070
[Journal Article] Interstitial lung disease with anti-melanoma differentiation-associated gene 5 antibody after allogeneic hematopoietic stem cell transplantation2022
- Author(s)
  Tamaki Masaharu、Matsumi Shimpei、Nakasone Hideki、Nakamura Yuhei、Kawamura Masakatsu、Kawamura Shunto、Takeshita Junko、Yoshino Nozomu、Misaki Yukiko、Yoshimura Kazuki、Gomyo Ayumi、Tanihara Aki、Okada Yosuke、Kusuda Machiko、Kameda Kazuaki、Kimura Shun-ichi、Kako Shinichi、Kanda Yoshinobu
- Journal Title
  
  Bone Marrow Transplantation
  
  Volume: 57 Issue: 9 Pages: 1382-1388
- DOI
  10.1038/s41409-022-01730-6
- Data Source
  KAKENHI-PROJECT-22K08463
[Journal Article] Deletion of Y chromosome before allogeneic hematopoietic stem cell transplantation in male recipients with female donors2022
- Author(s)
  Tamaki Masaharu、Kameda Kazuaki、Kimura Shun-ichi、Harada Naonori、Uchida Naoyuki、Doki Noriko、Tanaka Masatsugu、Ikegame Kazuhiro、Sawa Masashi、Katayama Yuta、Miyakoshi Shigesaburo、Ara Takahide、Kanda Junya、Onizuka Makoto、Fukuda Takahiro、Atsuta Yoshiko、Kanda Yoshinobu、Yakushijin Kimikazu、Nakasone Hideki
- Journal Title
  
  Blood Advances
  
  Volume: 6 Issue: 6 Pages: 1895-1903
- DOI
  10.1182/bloodadvances.2021006456
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20J14747, KAKENHI-PROJECT-21K07070
[Journal Article] Development of a Unique T Cell Receptor Gene-Transferred Tax-Redirected T Cell Immunotherapy for Adult T Cell Leukemia2020
- Author(s)
  Kawamura Koji、Tanaka Yukie、Nakasone Hideki、Ishihara Yuko、Kako Shinichi、Kobayashi Seiichiro、Tanaka Yuetsu、Ohmori Tsukasa、Uchimaru Kaoru、Okamoto Sachiko、Mineno Junichi、Shiku Hiroshi、Nishimura Satoshi、Kanda Yoshinobu
- Journal Title
  
  Biology of Blood and Marrow Transplantation
  
  Volume: 26 Issue: 8 Pages: 1377-1385
- DOI
  10.1016/j.bbmt.2020.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07292, KAKENHI-PROJECT-18K08369, KAKENHI-PROJECT-18K08370
[Journal Article] Increased Mac-2 binding protein glycan isomer in patients at risk for late nonrelapse mortality after HSCT2019
- Author(s)
  Akahoshi Yu、Nakasone Hideki、Kawamura Koji、Kusuda Machiko、Kawamura Shunto、Takeshita Junko、Yoshino Nozomu、Misaki Yukiko、Yoshimura Kazuki、Gomyo Ayumi、Tanihara Aki、Tamaki Masaharu、Kimura Shun-ichi、Kako Shinichi、Kanda Yoshinobu
- Journal Title
  
  Blood Advances
  
  Volume: 3 Issue: 21 Pages: 3287-3296
- DOI
  10.1182/bloodadvances.2019000629
- Data Source
  KAKENHI-PROJECT-18K08369
[Patent] 成人Ｔ細胞性白血病を含むＨＴＬＶ－１ウイルス感染に対する腫瘍抗原特異的Ｔ細胞2016
- Inventor(s)
  神田善伸、仲宗根秀樹、他
- Industrial Property Rights Holder
  自治医科大学、タカラバイオ株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-214426
- Filing Date
  2016-11-01
- Data Source
  KAKENHI-PROJECT-26290058
[Presentation] Development of Tax-redirected T-cell immunotherapy for adult T cell leukemia2017
- Author(s)
  Kawamura K, Nakasone H, Kanda Y, et al.
- Organizer
  European Hematoloy Association
- Place of Presentation
  Madrid
- Year and Date
  2017-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290058

1. KANDA YOSHINOBU (30334379)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
2. 諫田淳也 (30636311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 山崎理絵 (80365262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 小林誠一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 田中ゆきえ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 森島聡子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakasone Hideki 仲宗根 秀樹

NAKASONE Hideki 仲宗根 秀樹

Research Projects

Research Products

Co-Researchers

相乗的なHTLV-1増殖制御戦略に向けた免疫回避機序への介入とウイルス特異的T細胞療法Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

成人T細胞白血病リンパ腫に対する遺伝子導入細胞療法の至適化

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Sex-mismatched hematopoietic cell transplantation and acquisition of B-cells specific to antigens on Y-chromosomePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Preclinical research for the clinical application of T-cell receptor gene therapy targeting tax for adult T-cell leukemia/lymphoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A role of adipokine/related protein in chronic graft-versus-host disease after allogeneic hematopoietic cell transplantationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of redirected Tax-specific T-cell immunotherapy against adult T-cell leukemia/lymphoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Plasma ubiquitin C-terminal hydrolase-L1 (UCH-L1) level as a blood biomarker of neurological damage after allogeneic hematopoietic cell transplantation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of anti-thymocyte globulin on survival outcomes in female-to-male allogeneic hematopoietic stem cell transplantation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antibody-mediated pathogenesis of chronic GVHD through DBY/HLA class II complexes and induction of a GVL effect.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene expression and <scp>TCR</scp> amino acid sequences selected by <scp>HLA‐A02</scp>:01‐restricted <scp>CTLs</scp> specific to <scp>HTLV</scp>‐1 in <scp>ATL</scp> patients2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unrelated female-to-male bone marrow transplantation would be preferred over cord blood transplantation in male patients2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interstitial lung disease with anti-melanoma differentiation-associated gene 5 antibody after allogeneic hematopoietic stem cell transplantation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Deletion of Y chromosome before allogeneic hematopoietic stem cell transplantation in male recipients with female donors2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a Unique T Cell Receptor Gene-Transferred Tax-Redirected T Cell Immunotherapy for Adult T Cell Leukemia2020

Author(s)

Journal Title

DOI

Nakasone Hideki 仲宗根秀樹

NAKASONE Hideki 仲宗根秀樹