SATO TOSHIHIRO 佐藤紀宏

Researcher Number	50770723
Other IDs
Affiliation (Current)	2025: 東北大学, 大学病院, 助教
Affiliation (based on the past Project Information) *help	2020 – 2025: 東北大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords	Principal Investigator 肝障害 / OATP4C1 / バイオマーカー / TDM / トランスポーター / メタボローム解析 / 相互作用バイオマーカー / 薬物副作用回避 / 薬物-生体内物質相互作用 / 腎薬物トランスポーター … More / 薬物-胆汁酸相互作用 / 腎排泄型薬物 / 薬物相互作用 / 胆汁酸 / 副作用回避 / 薬物トランスポーター … More Except Principal Investigator メタボロミクス / バイオマーカー / 非アルコール性脂肪肝炎 / 生理機能解析 / 新奇脂質 / 脂質生理 / 創薬標的探索 / 疾患代謝 / マルチオミクス / 脂質 / LC-MS/MS / プロテオミクス / ニーマンピック病C型 Less

Establishing a Universal Platform for Assessing Transporter Function Variability Using Transporter-Specific BiomarkersPrincipal Investigator
- Principal Investigator
  
  佐藤紀宏
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tohoku University
非アルコール性脂肪肝炎の精密予後予測マーカー探索を指向した機能性脂質の網羅的解析
- Principal Investigator
  
  眞野成康
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Tohoku University
Identification and evaluation of novel biomarkers by metabolome analysis for drug interaction on renal drug transportersPrincipal Investigator
- Principal Investigator
  
  佐藤紀宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tohoku University
Elucidation of the molecular mechanism and pathophysiology of Niemann-Pick disease type C by a multifaceted approach
- Principal Investigator
  
  Maekawa Masamitsu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tohoku University
Drug-bile acid interaction study aiming to reduce the unexpected adverse effects of drugs through the evaluation of OATP4C1Principal Investigator
- Principal Investigator
  
  SATO TOSHIHIRO
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Tohoku University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] The Use of an Antioxidant Enables Accurate Evaluation of the Interaction of Curcumin on Organic Anion-Transporting Polypeptides 4C1 by Preventing Auto-Oxidation2024
- Author(s)
  Sato Toshihiro、Yagi Ayaka、Yamauchi Minami、Kumondai Masaki、Sato Yu、Kikuchi Masafumi、Maekawa Masamitsu、Yamaguchi Hiroaki、Abe Takaaki、Mano Nariyasu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 2 Pages: 991-991
- DOI
  10.3390/ijms25020991
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15311, KAKENHI-PROJECT-23K06231
[Journal Article] Global Proteomics for Identifying the Alteration Pathway of Niemann?Pick Disease Type C Using Hepatic Cell Models2023
- Author(s)
  Miyoshi Keitaro、Hishinuma Eiji、Matsukawa Naomi、Shirasago Yoshitaka、Watanabe Masahiro、Sato Toshihiro、Sato Yu、Kumondai Masaki、Kikuchi Masafumi、Koshiba Seizo、Fukasawa Masayoshi、Maekawa Masamitsu、Mano Nariyasu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 21 Pages: 15642-15642
- DOI
  10.3390/ijms242115642
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07814
[Journal Article] Identification cholesterol metabolites altered before the onset of nonalcoholic steatohepatitis by targeted metabolomics2022
- Author(s)
  Shoji Saori、Maekawa Masamitsu、Ogura Jiro、Sato Toshihiro、Mano Nariyasu
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  
  Volume: 1867 Issue: 5 Pages: 159135-159135
- DOI
  10.1016/j.bbalip.2022.159135
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16037
[Journal Article] Bile Acid-Drug Interaction via Organic Anion-Transporting Polypeptide 4C1 Is a Potential Mechanism of Altered Pharmacokinetics of Renally Excreted Drugs2022
- Author(s)
  Yamauchi Minami, Sato Toshihiro, Otake Ayana, Kumondai Masaki, Sato Yu, Kikuchi Masafumi, Maekawa Masamitsu, Yamaguchi Hiroaki, Abe Takaaki, Mano Nariyasu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 15 Pages: 8508-8508
- DOI
  10.3390/ijms23158508
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15311
[Journal Article] Metabolic Alteration Analysis of Steroid Hormones in Niemann?Pick Disease Type C Model Cell Using Liquid Chromatography/Tandem Mass Spectrometry2022
- Author(s)
  Abe Ai、Maekawa Masamitsu、Sato Toshihiro、Sato Yu、Kumondai Masaki、Takahashi Hayato、Kikuchi Masafumi、Higaki Katsumi、Ogura Jiro、Mano Nariyasu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 8 Pages: 4459-4459
- DOI
  10.3390/ijms23084459
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07814
[Journal Article] Development of a Highly Sensitive and Rapid Liquid Chromatography–Tandem Mass Spectrometric Method Using a Basic Mobile Phase Additive to Determine the Characteristics of the Urinary Metabolites for Niemann–Pick Disease Type C2022
- Author(s)
  Maekawa Masamitsu、Miyoshi Keitaro、Narita Aya、Sato Toshihiro、Sato Yu、Kumondai Masaki、Kikuchi Masafumi、Higaki Katsumi、Okuyama Torayuki、Eto Yoshikatsu、Sakamaki Hiroshi、Mano Nariyasu
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 9 Pages: 1259-1268
- DOI
  10.1248/bpb.b22-00185
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-09-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07814
[Journal Article] Role of OATP4C1 in Renal Handling of Remdesivir and its Nucleoside Analog GS-441524: The First Approved Drug for Patients with COVID-192021
- Author(s)
  Sato Toshihiro、Maekawa Masamitsu、Mano Nariyasu、Abe Takaaki、Yamaguchi Hiroaki
- Journal Title
  
  Journal of Pharmacy & Pharmaceutical Sciences
  
  Volume: 24 Pages: 227-236
- DOI
  10.18433/jpps31813
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16037
[Journal Article] Role of OATP4C1 in Renal Handling of Remdesivir and its Nucleoside Analog GS-441524: The First Approved Drug for Patients with COVID-192021
- Author(s)
  Toshihiro Sato, Masamitsu Maekawa, Nariyasu Mano, Takaaki Abe, Hiroaki Yamaguchi
- Journal Title
  
  Journal of Pharmacy & Pharmaceutical Sciences
  
  Volume: 24
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16037
[Presentation] 肝細胞癌バイオマーカー開発を目的とした肝疾患患者血漿中胆汁酸のLC/MS/MS分析2024
- Author(s)
  山内碧、佐藤紀宏、前川正充、眞野成康
- Organizer
  日本薬学会第144年会（横浜）
- Data Source
  KAKENHI-PROJECT-22K15311
[Presentation] 有機アニオン輸送ポリペプチド2B1における胆汁酸-薬物相互作用解析2024
- Author(s)
  三浦智行、佐藤紀宏、前川正充、眞野成康
- Organizer
  日本薬学会第144年会（横浜）
- Data Source
  KAKENHI-PROJECT-22K15311
[Presentation] 頭頸部癌における化学放射線療法施行中に下部消化管出血を来した1症例2023
- Author(s)
  佐藤朗、佐藤紀宏、前川正充、眞野成康
- Organizer
  第33回日本医療薬学会年会（仙台）
- Data Source
  KAKENHI-PROJECT-22K15311
[Presentation] 個別化医療提供を目指したトランスポーター相互作用研究～肝疾患時の血中胆汁酸濃度解析例を中心に～2023
- Author(s)
  佐藤紀宏、前川正充、眞野成康
- Organizer
  日本薬学会第143年会（札幌）
- Invited
- Data Source
  KAKENHI-PROJECT-22K15311
[Presentation] 薬剤師による薬物相互作用マネジメントの実態調査2023
- Author(s)
  臼井拓也、佐藤紀宏、坂本光太郎、前川正充、眞野成康
- Organizer
  第77回医薬品相互作用研究会シンポジウム（郡山）
- Data Source
  KAKENHI-PROJECT-22K15311
[Presentation] 核内レセプターFXRおよびLXRを介した有機アニオン輸送ポリペプチド4C1の発現制御に関する基礎的検討2023
- Author(s)
  山内碧、佐藤紀宏、前川正充、山口浩明、阿部高明、眞野成康
- Organizer
  第44回胆汁酸研究会（名古屋）
- Data Source
  KAKENHI-PROJECT-22K15311
[Presentation] シスプラチン治療における急性腎障害の診断に関する現状分析2023
- Author(s)
  大竹彩奈、佐藤紀宏、近藤宏輝、大久保美祐、臼井拓也、佐藤祐司、前川正充、眞野成康
- Organizer
  第17回日本腎臓病薬物療法学会学術集会・総会（名古屋）
- Data Source
  KAKENHI-PROJECT-22K15311
[Presentation] 肝障害時の腎排泄型薬物の投与設計最適化を目指したOATP4C1 における胆汁酸-薬物相互作用研究2022
- Author(s)
  山内碧、佐藤紀宏、大竹彩奈、公文代將希、佐藤裕、菊地正史、山口浩明、阿部高明、前川正充、眞野成康
- Organizer
  第32回日本医療薬学会年会（高崎）
- Data Source
  KAKENHI-PROJECT-22K15311
[Presentation] 東北大学病院における新型コロナウイルスワクチン接種による副反応調査2022
- Author(s)
  佐藤智見、佐藤裕、鷹尾月舟、佐藤朗、菅原英里奈、鈴木博也、公文代將希、佐藤紀宏、前川正充、徳田浩一、眞野成康
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K16037
[Presentation] 臨床現場における薬物相互作用研究～調査研究とトランスポーター研究への取り組み～2022
- Author(s)
  佐藤紀宏
- Organizer
  第8回日本医薬品安全性学会学術大会（Web開催）
- Invited
- Data Source
  KAKENHI-PROJECT-22K15311
[Presentation] 薬物相互作用に着目した東北大学病院の疑義照会・副作用報告・プレアボイド事例集解析2022
- Author(s)
  坂本光太郎、佐藤紀宏、臼井拓也、佐藤裕、前川麻央、佐藤祐司、前川正充、眞野成康
- Organizer
  第152回宮城県病院薬剤師会学術研究発表会
- Data Source
  KAKENHI-PROJECT-20K16037
[Presentation] LC/MS/MSを用いるニーマンピック病C型モデル細胞におけるステロイドホルモンの代謝変動解析2022
- Author(s)
  阿部愛, 前川正充, 佐藤紀宏, 佐藤裕, 公文代將希, 高橋勇人, 菊地正史, 檜垣克美, 小倉次郎, 眞野成康
- Organizer
  第47回日本医用マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-21K07814
[Presentation] OATP4C1におけるフラボノイド類-薬物相互作用の解析2022
- Author(s)
  八木文佳、佐藤紀宏、山内碧、川上佳織、前川正充、眞野成康
- Organizer
  第61日本薬学会東北支部大会（Web開催）
- Data Source
  KAKENHI-PROJECT-22K15311
[Presentation] 新型コロナウイルス感染症治療薬レムデシビルおよびGS-441524の腎排泄および薬物相互作用におけるOATP4C1の役割2021
- Author(s)
  佐藤紀宏、前川正充、阿部高明、山口浩明、眞野成康
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K16037
[Presentation] 安全な薬物療法の提供を目指した薬物相互作用研究2021
- Author(s)
  佐藤紀宏
- Organizer
  PPF2020/2021・第18回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-20K16037
[Presentation] 抗精神病薬および併用薬の処方状況とCYPを介した薬物間相互作用の可能性に関する調査2021
- Author(s)
  横田真希、前川正充、鈴木直人、小林大典、鈴鹿雅人、佐藤祐司、公文代將希、佐藤裕、佐藤紀宏、菊地正史、眞野成康
- Organizer
  第31回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-20K16037
[Presentation] 新型コロナウイルス感染症治療に使用されるレムデシビル、ファビピラビルおよびエトポシドのLC-MS/MS定量法の構築2021
- Author(s)
  髙﨑新也、佐藤稔之、鈴木博也、青柳哲史、森下啓、千葉僚、佐藤裕、佐藤紀宏、菊地正史、大島謙吾、徳田浩一、前川正充、眞野成康
- Organizer
  第46回日本医用マススペクトル学会年会
- Data Source
  KAKENHI-PROJECT-20K16037
[Presentation] 薬剤師教育を主目的とした病棟疑義照会・副作用報告・プレアボイド事例集の解析：薬物間相互作用に着目して2021
- Author(s)
  臼井拓也、佐藤紀宏、佐藤裕、前川麻央、佐藤祐司、前川正充、眞野成康
- Organizer
  第31回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-20K16037
[Presentation] 東北大学病院で新型コロナウイルス感染症（COVID-19）治療に用いた薬物の血中濃度と臨床指標との相関解析2021
- Author(s)
  佐藤稔之、髙﨑新也、森下啓、千葉僚、小林大典、鈴木博也、佐藤裕、佐藤紀宏、菊地正史、早川禎宏、杉浦久敏、青柳哲史、前川正充、眞野成康
- Organizer
  第31回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-20K16037

1. Maekawa Masamitsu (70572882)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 眞野成康 (50323035)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results

SATO TOSHIHIRO 佐藤 紀宏

Research Projects

Research Products

Co-Researchers

Establishing a Universal Platform for Assessing Transporter Function Variability Using Transporter-Specific BiomarkersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非アルコール性脂肪肝炎の精密予後予測マーカー探索を指向した機能性脂質の網羅的解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and evaluation of novel biomarkers by metabolome analysis for drug interaction on renal drug transportersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanism and pathophysiology of Niemann-Pick disease type C by a multifaceted approach

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Drug-bile acid interaction study aiming to reduce the unexpected adverse effects of drugs through the evaluation of OATP4C1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The Use of an Antioxidant Enables Accurate Evaluation of the Interaction of Curcumin on Organic Anion-Transporting Polypeptides 4C1 by Preventing Auto-Oxidation2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Global Proteomics for Identifying the Alteration Pathway of Niemann?Pick Disease Type C Using Hepatic Cell Models2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification cholesterol metabolites altered before the onset of nonalcoholic steatohepatitis by targeted metabolomics2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bile Acid-Drug Interaction via Organic Anion-Transporting Polypeptide 4C1 Is a Potential Mechanism of Altered Pharmacokinetics of Renally Excreted Drugs2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolic Alteration Analysis of Steroid Hormones in Niemann?Pick Disease Type C Model Cell Using Liquid Chromatography/Tandem Mass Spectrometry2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a Highly Sensitive and Rapid Liquid Chromatography–Tandem Mass Spectrometric Method Using a Basic Mobile Phase Additive to Determine the Characteristics of the Urinary Metabolites for Niemann–Pick Disease Type C2022

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Role of OATP4C1 in Renal Handling of Remdesivir and its Nucleoside Analog GS-441524: The First Approved Drug for Patients with COVID-192021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of OATP4C1 in Renal Handling of Remdesivir and its Nucleoside Analog GS-441524: The First Approved Drug for Patients with COVID-192021

Author(s)

Journal Title

Data Source

[Presentation] 肝細胞癌バイオマーカー開発を目的とした肝疾患患者血漿中胆汁酸のLC/MS/MS分析2024

Author(s)

Organizer

Data Source

SATO TOSHIHIRO 佐藤紀宏

[Presentation] 臨床現場における薬物相互作用研究～調査研究とトランスポーター研究への取り組み～2022

[Presentation] LC/MS/MSを用いるニーマンピック病C型モデル細胞におけるステロイドホルモンの代謝変動解析2022