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ONO Hideaki  小野 秀明

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Ono Hideaki  小野 秀明

小野 秀明  オノ ヒデアキ

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Researcher Number 50771846
Other IDs
Affiliation (Current) 2026: 東京大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help 2024 – 2026: 東京大学, 医学部附属病院, 講師
2021 – 2024: 埼玉医科大学, 医学部, 客員准教授
2016 – 2018: 東京大学, 医学部附属病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 56010:Neurosurgery-related
Except Principal Investigator
Basic Section 56010:Neurosurgery-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Neurosurgery
Keywords
Principal Investigator
次世代シークエンサー / somatic mutation / germline mutation / 遺伝子解析 / 脳動静脈奇形
Except Principal Investigator
Tetra-PEG Gel / 末梢神経再生 / 動物モデル / digital droplet PCR / gap junction … More / hemichannel / GJA4 / long read sequencing / long read sequence / RNF213 / もやもや病 / エクソソーム / 再生 / 細胞移植治療 / 白質障害 / 運動機能 / ネットワーク / 再現性 / 定位脳手術 / エンドセリン / 内包 / 大脳白質梗塞 / ラット / ドラッグデリバリーシステム / ヒト由来神経栄養因子 / ヒト骨髄由来細胞 / 白質障害モデル / 細胞移植 / ラット前脳虚血 / 脳梗塞実験モデル / 膿保護作用 / BDNF mRNA / ドラッグデリバリー / 脳梗塞 / mRNA delivery / BDNFmRNA / 全脳虚血モデル / 二重盲検比較対照第II相試験 / 加工幹細胞SB623 / 骨髄由来間葉系幹細胞 / 大脳白質障害 / 再生医療 Less
  • Research Projects

    (6 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (13 People)
  •  脳血管奇形の疾患特異性を規定する分子メカニズムの解明Principal Investigator

    • Principal Investigator
      小野 秀明
    • Project Period (FY)
      2026 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      The University of Tokyo
  •  Development of Novel Therapeutic Strategies for Cerebral Cavernous Malformations Based on Functional Analysis of the GJA4 Gene

    • Principal Investigator
      齊藤 延人
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      The University of Tokyo
  •  Development of a Novel Therapeutic Approach for Peripheral Nerve Regeneration Using Tetra-PEG Gel

    • Principal Investigator
      宮脇 哲
    • Project Period (FY)
      2025 – 2026
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      The University of Tokyo
  •  Elucidation of genetic factors of moyamoya disease and search for therapeutic targets using long read sequencing

    • Principal Investigator
      宮脇 哲
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      The University of Tokyo
  •  Elucidation of the pathogenesis of cerebral arteriovenous malformations and search for therapeutic targets by multidimensional genetic analysisPrincipal Investigator

    • Principal Investigator
      Ono Hideaki
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      The University of Tokyo
      Saitama Medical University
  •  Basic research for regenerative medicine for white matter disorder in central nervous system

    • Principal Investigator
      Imai Hideaki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      The University of Tokyo

All 2023 2016

All Journal Article Presentation

  • [Journal Article] RNF213 p.Arg4810Lys Wild Type is Associated with De Novo Hemorrhage in Asymptomatic Hemispheres with Moyamoya Disease2023

    • Author(s)
      Torazawa Seiei、Miyawaki Satoru、Imai Hideaki、Hongo Hiroki、Ishigami Daiichiro、Shimizu Masahiro、Ono Hideaki、Shinya Yuki、Sato Daisuke、Sakai Yu、Umekawa Motoyuki、Kiyofuji Satoshi、Shimada Daisuke、Koizumi Satoshi、Komura Daisuke、Katoh Hiroto、Ishikawa Shumpei、Nakatomi Hirofumi、Teraoka Akira、Saito Nobuhito
    • Journal Title

      Translational Stroke Research

      Volume: 15(4) Issue: 4 Pages: 729-738

    • DOI

      10.1007/s12975-023-01159-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H03041, KAKENHI-PROJECT-23K27709
  • [Journal Article] Rat white matter injury model induced by endothelin-1 injection: technical modification and pathological evaluation.2016

    • Author(s)
      Ono H, Imai H, Miyawaki S, Nakatomi H, Saito N
    • Journal Title

      Acta Neurobiol Exp (Wars).

      Volume: 76 Pages: 212-24

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K10710
  • [Presentation] Genome-Wide association studyによる頭蓋内血管狭窄の遺伝的要因の探索2023

    • Author(s)
      宮脇哲、堂福翔吾、曽根原究人、今井英明、清水暢裕、本郷博貴、新谷祐貴、小原健太、寺西裕、岡野淳、小野秀明、中冨浩文、寺岡暉、岡田随象、斉藤延人
    • Organizer
      第66回日本脳循環代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K27709
  • [Presentation] RNF213遺伝子全体の変異解析を通じたもやもや病の遺伝子型と臨床表現型との関連解析2023

    • Author(s)
      宮脇哲、虎澤誠英、今井英明、清水暢裕、小野秀明、新谷祐貴、本郷博貴、石神大一郎、酒井優、梅川元之、清藤哲史、島田大輔、小泉聡、中冨浩文、寺岡暉、齊藤延人
    • Organizer
      第66回日本脳循環代謝学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K27709
  • [Presentation] RNF213 p.Arg4810Lys heterozygote is associated with early onset and bilateral cerebrovascular events in Moyamoya disase2023

    • Author(s)
      Satoru Miyawaki, Daiichiro Ishigami, Hideaki Imai, Masahiro Shimizu, Hiroki Hongo, Shogo Dofuku, Kenta Ohara, Yu Teranishi, Daisuke Shimada, Satoshi Koizumi, Hideaki Ono, Yudai Hirano, Masafumi Segawa, Hirofumi Nakatomi, Nobuhito Saito.
    • Organizer
      Human Genetics Asia 2023(HGA2023)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27709
  • 1.  宮脇 哲 (70407914)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 5 results
  • 2.  齊藤 延人 (60262002)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  Imai Hideaki (70359587)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  石崎 泰樹 (90183003)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  位高 啓史 (60292926)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  岡田 随象 (70727411)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  本郷 博貴 (80908682)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 8.  森下 真一 (90292854)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  石川 俊平 (50418638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  三井 純 (70579862)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  酒井 崇匡 (70456151)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  Fukushima Yuta
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  斎藤 延人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results

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