Ohno Marumi 大野円実

Researcher Number	50794202
Other IDs
Affiliation (Current)	2025: 北海道大学, 人獣共通感染症国際共同研究所 , 助教
Affiliation (based on the past Project Information) *help	2021 – 2023: 北海道大学, 人獣共通感染症国際共同研究所, 助教 2017 – 2019: 北海道大学, 人獣共通感染症リサーチセンター, 博士研究員
Review Section/Research Field	Principal Investigator Basic Section 42030:Animal life science-related / Veterinary medical science
Keywords	Principal Investigator エネルギー代謝障害 / インフルエンザ / 生体応答 / ウイルス感染症 / 血液凝固異常 / 脂質代謝 / 宿主因子 / LOX-1 / 宿主応答 / 生理学 … More / 感染症 / エネルギー代謝制御 / エネルギー代謝 / インスリン感受性 Less

Research of novel treatments for severe influenza by controlling host factorsPrincipal Investigator
- Principal Investigator
  
  Ohno Marumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Hokkaido University
Research on host factors involved in influenza pathogenesisPrincipal Investigator
- Principal Investigator
  
  Ohno Marumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2019

All Journal Article Presentation

[Journal Article] Extraction of the CDRH3 sequence of the mouse antibody repertoire selected upon influenza virus infection by subtraction of the background antibody repertoire2024
- Author(s)
  Shingai Masashi、Iida Sayaka、Kawai Naoko、Kawahara Mamiko、Sekiya Toshiki、Ohno Marumi、Nomura Naoki、Handabile Chimuka、Kawakita Tomomi、Omori Ryosuke、Yamagishi Junya、Sano Kaori、Ainai Akira、Suzuki Tadaki、Ohnishi Kazuo、Ito Kimihito、Kida Hiroshi
- Journal Title
  
  Journal of Virology
  
  Volume: 98 Issue: 3
- DOI
  10.1128/jvi.01995-23
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15362, KAKENHI-PROJECT-19K17947, KAKENHI-PROJECT-21H02376, KAKENHI-PROJECT-23K21692, KAKENHI-PROJECT-23K27422
[Journal Article] Increased expression of CD38 on endothelial cells in SARS-CoV-2 infection in cynomolgus macaques2024
- Author(s)
  Nguyen Cong Thanh、Nakayama Misako、Ishigaki Hirohito、Kitagawa Yoshinori、Kakino Akemi、Ohno Marumi、Shingai Masashi、Suzuki Yasuhiko、Sawamura Tatsuya、Kida Hiroshi、Itoh Yasushi
- Journal Title
  
  Virology
  
  Volume: 594 Pages: 110052-110052
- DOI
  10.1016/j.virol.2024.110052
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07921, KAKENHI-PROJECT-21H02376
[Journal Article] The elucidation of plasma lipidome profiles during severe influenza in a mouse model2023
- Author(s)
  Ohno Marumi、Gowda Siddabasave Gowda B.、Sekiya Toshiki、Nomura Naoki、Shingai Masashi、Hui Shu-Ping、Kida Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 14210-14210
- DOI
  10.1038/s41598-023-41055-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02376
[Journal Article] Assessing the pyrogenicity of whole influenza virus particle vaccine in cynomolgus macaques2023
- Author(s)
  Ohno Marumi、Sagata Masataka、Sekiya Toshiki、Nomura Naoki、Shingai Masashi、Endo Masafumi、Kimachi Kazuhiko、Suzuki Saori、Thanh Nguyen Cong、Nakayama Misako、Ishigaki Hirohito、Ogasawara Kazumasa、Itoh Yasushi、Kino Yoichiro、Kida Hiroshi
- Journal Title
  
  Vaccine
  
  Volume: 41 Issue: 3 Pages: 787-794
- DOI
  10.1016/j.vaccine.2022.12.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02376
[Journal Article] Immunization with inactivated whole virus particle influenza virus vaccines improves the humoral response landscape in cynomolgus macaques2022
- Author(s)
  Chua BY、Sekiya T、Koutsakos M、Nomura N、Rowntree LC、Nguyen THO、McQuilten HA、Ohno M、Ohara Y、Nishimura T、Endo M、Itoh Y、Habel JR、Selva KJ、Wheatley AK、Wines BD、Hogarth PM、Kent SJ、Chung AW、Jackson DC、Brown LE、Shingai M、Kedzierska K、Kida H
- Journal Title
  
  PLOS Pathogens
  
  Volume: 18 Issue: 10 Pages: e1010891-e1010891
- DOI
  10.1371/journal.ppat.1010891
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02376
[Journal Article] Inactivated whole influenza virus particle vaccines induce neutralizing antibodies with an increase in immunoglobulin gene subclones of B-lymphocytes in cynomolgus macaques2022
- Author(s)
  Shiohara M、Suzuki Saori、Shichinohe S、Ishigaki H、Nakayama M、Nomura N、Shingai M、Sekiya T、Ohno M、Iida S、Kawai N、Kawahara M、Yamagishi J、Ito K、Mitsumata R、Ikeda T、Motokawa K、Sobue T、Kida H、Ogasawara K、Itoh Y
- Journal Title
  
  Vaccine
  
  Volume: 40 Issue: 30 Pages: 4026-4037
- DOI
  10.1016/j.vaccine.2022.05.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02376, KAKENHI-PROJECT-23K21692
[Journal Article] Inactivated Whole Virus Particle Influenza Vaccine Induces Anti-Neuraminidase Antibodies That May Contribute to Cross-Protection against Heterologous Virus Infection2022
- Author(s)
  Handabile Chimuka、Sekiya Toshiki、Nomura Naoki、Ohno Marumi、Kawakita Tomomi、Shingai Masashi、Kida Hiroshi
- Journal Title
  
  Vaccines
  
  Volume: 10 Issue: 5 Pages: 804-804
- DOI
  10.3390/vaccines10050804
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02376
[Journal Article] Determination of short-chain fatty acids by N,N-dimethylethylenediamine derivatization combined with liquid chromatography/mass spectrometry and their implication in influenza virus infection2022
- Author(s)
  Gowda Divyavani、Li Yonghan、B Gowda Siddabasave Gowda、Ohno Marumi、Chiba Hitoshi、Hui Shu-Ping
- Journal Title
  
  Analytical and Bioanalytical Chemistry
  
  Volume: 414 Issue: 22 Pages: 6419-6430
- DOI
  10.1007/s00216-022-04217-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02376
[Journal Article] Critical role of oxidized LDL receptor-1 in intravascular thrombosis in a severe influenza mouse model2021
- Author(s)
  Ohno Marumi、Kakino Akemi、Sekiya Toshiki、Nomura Naoki、Shingai Masashi、Sawamura Tatsuya、Kida Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-95046-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02376
[Journal Article] Defining the kinetic effects of infection with influenza virus A/PR8/34 (H1N1) on sphingosine-1-phosphate signaling in mice by targeted LC/MS2021
- Author(s)
  Gowda Divyavani、Ohno Marumi、B. Gowda Siddabasave Gowda、Chiba Hitoshi、Shingai Masashi、Kida Hiroshi、Hui Shu-Ping
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 20161-20161
- DOI
  10.1038/s41598-021-99765-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02376, KAKENHI-PROJECT-21K14812
[Journal Article] Abnormal Blood Coagulation and Kidney Damage in Aged Hamsters Infected with Severe Acute Respiratory Syndrome Coronavirus 22021
- Author(s)
  Ohno Marumi、Sasaki Michihito、Orba Yasuko、Sekiya Toshiki、Masum Md. Abdul、Ichii Osamu、Sawamura Tatsuya、Kakino Akemi、Suzuki Yasuhiko、Kida Hiroshi、Sawa Hirofumi、Shingai Masashi
- Journal Title
  
  Viruses
  
  Volume: 13 Issue: 11 Pages: 2137-2137
- DOI
  10.3390/v13112137
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02376
[Journal Article] Selecting and Using the Appropriate Influenza Vaccine for Each Individual2021
- Author(s)
  Sekiya Toshiki、Ohno Marumi、Nomura Naoki、Handabile Chimuka、Shingai Masashi、Jackson David C.、Brown Lorena E.、Kida Hiroshi
- Journal Title
  
  Viruses
  
  Volume: 13 Issue: 6 Pages: 971-971
- DOI
  10.3390/v13060971
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02376
[Journal Article] Detection and Structural Characterization of SFAHFA Homologous Series in Mouse Colon Contents by LTQ-Orbitrap-MS and Their Implication in Influenza Virus Infection2021
- Author(s)
  B. Gowda Siddabasave Gowda、Gowda Divyavani、Ohno Marumi、Liang Chongsheng、Chiba Hitoshi、Hui Shu-Ping
- Journal Title
  
  Journal of the American Society for Mass Spectrometry
  
  Volume: 32 Issue: 8 Pages: 2196-2205
- DOI
  10.1021/jasms.1c00138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02376
[Journal Article] Potent priming by inactivated whole influenza virus particle vaccines is linked to viral RNA uptake into antigen presenting cells2021
- Author(s)
  Shingai Masashi、Nomura Naoki、Sekiya Toshiki、Ohno Marumi、et al.,
- Journal Title
  
  Vaccine
  
  Volume: 39 Issue: 29 Pages: 3940-3951
- DOI
  10.1016/j.vaccine.2021.05.065
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02376
[Journal Article] Updating the influenza virus library at Hokkaido University -It's potential for the use of pandemic vaccine strain candidates and diagnosis2021
- Author(s)
  Nomura Naoki、Matsuno Keita、Shingai Masashi、Ohno Marumi、Sekiya Toshiki、Omori Ryosuke、Sakoda Yoshihiro、Webster Robert G.、Kida Hiroshi
- Journal Title
  
  Virology
  
  Volume: 557 Pages: 55-61
- DOI
  10.1016/j.virol.2021.02.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07135, KAKENHI-PROJECT-21H02376
[Presentation] 重症インフルエンザにおけるリン脂質の代謝異常とその生理学的意義2023
- Author(s)
  大野円実
- Organizer
  第34回日本生体防御学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02376
[Presentation] Characteristic lipid profiles in severe influenza2022
- Author(s)
  Marumi Ohno, Siddabasave Gowda B. Gowda, Masashi Shingai, Hiroshi Kida
- Organizer
  第69回日本ウイルス学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02376
[Presentation] カニクイザルにおける不活化インフルエンザウイルス全粒子ワクチンの発熱源性の解析2022
- Author(s)
  大野円実、佐潟雅隆、遠藤昌史、鈴木紗織、伊藤靖、新開大史、喜田宏
- Organizer
  第26回日本ワクチン学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02376
[Presentation] Influenza virus infection causes disorder of energy metabolism and blood coagulation.2021
- Author(s)
  Marumi Ohno
- Organizer
  BioST2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02376
[Presentation] Effects of Influenza Virus Infection on Insulin Signaling and Fatty Acid Metabolism in the Host2019
- Author(s)
  大野円実
- Organizer
  日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-17K15367

1. KITAGAWA Yoshinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 河喜多智美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 喜田宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 新開大史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohno Marumi 大野 円実

Research Projects

Research Products

Co-Researchers

Research of novel treatments for severe influenza by controlling host factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on host factors involved in influenza pathogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Extraction of the CDRH3 sequence of the mouse antibody repertoire selected upon influenza virus infection by subtraction of the background antibody repertoire2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased expression of CD38 on endothelial cells in SARS-CoV-2 infection in cynomolgus macaques2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The elucidation of plasma lipidome profiles during severe influenza in a mouse model2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Assessing the pyrogenicity of whole influenza virus particle vaccine in cynomolgus macaques2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunization with inactivated whole virus particle influenza virus vaccines improves the humoral response landscape in cynomolgus macaques2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inactivated whole influenza virus particle vaccines induce neutralizing antibodies with an increase in immunoglobulin gene subclones of B-lymphocytes in cynomolgus macaques2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inactivated Whole Virus Particle Influenza Vaccine Induces Anti-Neuraminidase Antibodies That May Contribute to Cross-Protection against Heterologous Virus Infection2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Determination of short-chain fatty acids by N,N-dimethylethylenediamine derivatization combined with liquid chromatography/mass spectrometry and their implication in influenza virus infection2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Critical role of oxidized LDL receptor-1 in intravascular thrombosis in a severe influenza mouse model2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Defining the kinetic effects of infection with influenza virus A/PR8/34 (H1N1) on sphingosine-1-phosphate signaling in mice by targeted LC/MS2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Abnormal Blood Coagulation and Kidney Damage in Aged Hamsters Infected with Severe Acute Respiratory Syndrome Coronavirus 22021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Selecting and Using the Appropriate Influenza Vaccine for Each Individual2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection and Structural Characterization of SFAHFA Homologous Series in Mouse Colon Contents by LTQ-Orbitrap-MS and Their Implication in Influenza Virus Infection2021

Author(s)

Journal Title

DOI

Ohno Marumi 大野円実