Kashima Soki 嘉島相輝

Researcher Number	50842952
Other IDs
Affiliation (Current)	2022: 秋田大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2020 – 2022: 秋田大学, 医学系研究科, 助教 2019: 京都大学, 医学研究科, 特定病院助教
Review Section/Research Field	Principal Investigator 0901:Oncology and related fields / Basic Section 56030:Urology-related Except Principal Investigator Basic Section 56030:Urology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 47040:Pharmacology-related
Keywords	Principal Investigator iPS細胞 / CAR-T / 固形がん / HLA / T細胞 / 免疫療法 / 前立腺癌 / ゼノグラフト / CAR-T細胞療法 / 腎細胞癌 … More / 免疫チェックポイント阻害薬 / バイオマーカー / PD-1 / PD-L1 … More Except Principal Investigator 腎癌 / 前立腺癌 / 癌免疫 / 癌ニッチ / ゼノグラフト / シンジェニックマウス / 肥満 / 腸内細菌叢 / 高脂肪食 / 飽和脂肪酸 / 泌尿器癌 / 食事 / 治療抵抗性 / 腸内細菌 / 腫瘍周囲微小環境 / T細胞 / 泌尿器がん / 免疫チェックポイント阻害剤 / HLA / 腎細胞がん / 尿路上皮がん / KIR Less

T cell immune microenvironment on prostate cancer progression through the modulation of gut microbiome
- Principal Investigator
  
  成田伸太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Akita University
Molecular mechanisms and target molecules associated with progression and treatment resistance of urologic cancers associated with microbiome alterations by diet and obesity
- Principal Investigator
  
  羽渕友則
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Akita University
免疫チェックポイント阻害薬の治療有効性・抵抗性の要因評価～宿主腫瘍HLA環境解析
- Principal Investigator
  
  藤山信弘
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Akita University
腎細胞癌における免疫チェックポイント阻害薬の治療効果を予測するバイオマーカー探索Principal Investigator
- Principal Investigator
  
  嘉島相輝
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Akita University
次世代ヒト化シンジェニックマウスによる腎癌免疫ニッチの再現と治療評価モデルの樹立
- Principal Investigator
  
  小川修
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kyoto University
Development of CAR-T cell therapy derived from iPS cells for solid tumorPrincipal Investigator
- Principal Investigator
  
  Kashima Soki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Akita University
  Kyoto University

All 2022 2021

All Journal Article Presentation

[Journal Article] Specific Gut Microbial Environment in Lard Diet-Induced Prostate Cancer Development and Progression2022
- Author(s)
  Sato H, Narita S, Ishida M, Takahashi Y, Mingguo H, Kashima S, Yamamoto R, Koizumi A, Nara T, Numakura K, Saito M, Yoshioka T, Habuchi T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 Pages: 2214-2214
- DOI
  10.3390/ijms23042214
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09663, KAKENHI-PROJECT-21H03064, KAKENHI-PROJECT-18K06981, KAKENHI-PROJECT-21K06880
[Journal Article] Altering phosphoinositides in high‐fat diet‐associated prostate tumor xenograft growth2021
- Author(s)
  Huang Mingguo、Koizumi Atsushi、Narita Shintaro、Nakanishi Hiroki、Sato Hiromi、Kashima Soki、Nara Taketoshi、Kanda Sohei、Numakura Kazuyuki、Saito Mitsuru、Satoh Shigeru、Nanjo Hiroshi、Sasaki Takehiko、Habuchi Tomonori
- Journal Title
  
  MedComm
  
  Volume: 2 Pages: 756-764
- DOI
  10.1002/mco2.89
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18084, KAKENHI-PROJECT-21H03064, KAKENHI-PROJECT-21K19329
[Presentation] iPS細胞技術を融合した前立腺癌に対するCAR-T細胞療法の開発2021
- Author(s)
  嘉島相輝
- Organizer
  第16回 Basic Urology Research Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-19K23913
[Presentation] Impact of germline HLA status on clinical outcomes in patients with chemoresistant urothelial cancer treated with pembrolizumab2021
- Author(s)
  Shintaro Narita, Nobuhiro Fujiyama, Syuhei Takahashi, Takashi Kobayashi, Shingo Hatakeyama, Sei Naito, Renpei Kato, Toru Sakatani, Soki Kashima, Ryohei Yamamoto, Atsushi Koizumi, Taketoshi Nara, Kazuyuki Numakura, Mitsuru Saito, Tomonori Habuchi
- Organizer
  The 116th Annual Meeting of the American Urological Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06592

1. 成田伸太郎 (40396552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. 小川修 (90260611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 中村英二郎 (90293878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 後藤崇之 (90806605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 羽渕友則 (00293861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 堂前直 (00321787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 南條博 (70250892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 土谷順彦 (70282176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 大山力 (80282135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 沼倉一幸 (90566415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 藤山信弘 (90603275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 細道一善 (50420948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SAITO Mitsuru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. YOSHIOKA Toshiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 佐々木雄彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kashima Soki 嘉島 相輝

Research Projects

Research Products

Co-Researchers

T cell immune microenvironment on prostate cancer progression through the modulation of gut microbiome

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms and target molecules associated with progression and treatment resistance of urologic cancers associated with microbiome alterations by diet and obesity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

免疫チェックポイント阻害薬の治療有効性・抵抗性の要因評価～宿主腫瘍HLA環境解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腎細胞癌における免疫チェックポイント阻害薬の治療効果を予測するバイオマーカー探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

次世代ヒト化シンジェニックマウスによる腎癌免疫ニッチの再現と治療評価モデルの樹立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of CAR-T cell therapy derived from iPS cells for solid tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Specific Gut Microbial Environment in Lard Diet-Induced Prostate Cancer Development and Progression2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Altering phosphoinositides in high‐fat diet‐associated prostate tumor xenograft growth2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] iPS細胞技術を融合した前立腺癌に対するCAR-T細胞療法の開発2021

Author(s)

Organizer

Data Source

[Presentation] Impact of germline HLA status on clinical outcomes in patients with chemoresistant urothelial cancer treated with pembrolizumab2021

Author(s)

Organizer

Data Source

Kashima Soki 嘉島相輝