Hishikawa Akihito 菱川彰人

… Alternative Names

HISHIKAWA Akihito 菱川彰人

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Researcher Number	50867489
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 慶應義塾大学, 医学部(信濃町), 助教
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related Except Principal Investigator Basic Section 53040:Nephrology-related / Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator 臓器連関 / DNA損傷修復 / 慢性腎臓病 / 尿細管糸球体フィードバック / エピゲノム / プレコンディショニング効果 / DNA損傷 / 急性腎障害（AKI） Except Principal Investigator 慢性腎臓病 / 血球 … More / DNA損傷修復 / エピゲノム / DNAメチル化 / DNA損傷 / 尿サンプル / 尿中赤血球 / Deep learning / AI / 血尿 / ポドサイト Less

腎臓におけるDNA損傷修復と全身代謝変容連関の解明Principal Investigator
- Principal Investigator
  
  菱川彰人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Keio University
尿中細胞の深層学習・画像解析による腎疾患早期診断方法の開発
- Principal Investigator
  
  林香
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Keio University
血球細胞DNAメチル化をターゲットとした慢性腎臓病新規治療戦略の開発
- Principal Investigator
  
  林香
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Keio University
Regulatory mechanism of anion transporter mediated by DNA repair factor in acute kidney injuryPrincipal Investigator
- Principal Investigator
  
  HISHIKAWA Akihito
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Keio University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Podocyte Ercc1 is indispensable for glomerular integrity2024
- Author(s)
  Hama Eriko Yoshida、Nakamichi Ran、Hishikawa Akihito、Kihara Miho、Abe Takaya、Yoshimoto Norifumi、Nishimura Erina Sugita、Itoh Hiroshi、Hayashi Kaori
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 704 Pages: 149713-149713
- DOI
  10.1016/j.bbrc.2024.149713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18270, KAKENHI-PROJECT-22K19511, KAKENHI-PROJECT-23K24351
[Journal Article] Significance of podocyte DNA damage and glomerular DNA methylation in CKD patients with proteinuria2023
- Author(s)
  Yoshimoto Norifumi、Hayashi Kaori、Hishikawa Akihito、Hashiguchi Akinori、Nakamichi Ran、Sugita-Nishimura Erina、Yoshida-Hama Eriko、Azegami Tatsuhiko、Nakayama Takashin、Itoh Hiroshi
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 4 Pages: 1000-1008
- DOI
  10.1038/s41440-023-01169-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00535, KAKENHI-PROJECT-22K19511, KAKENHI-PROJECT-23K24351
[Journal Article] Plasminogen activator inhibitor 1 is not a major causative factor for exacerbation in a mouse model of SARS-CoV-2 infection2023
- Author(s)
  Nakayama Takashin、Azegami Tatsuhiko、Kiso Maki、Imai Masaki、Uraki Ryuta、Hayashi Kaori、Hishikawa Akihito、Yoshimoto Norifumi、Nakamichi Ran、Sugita-Nishimura Erina、Yoshida-Hama Eriko、Kawaoka Yoshihiro、Itoh Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 3103-3103
- DOI
  10.1038/s41598-023-30305-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19511, KAKENHI-PROJECT-20H00535, KAKENHI-PROJECT-21K18270
[Journal Article] DNA-damaged podocyte-CD8 T?cell crosstalk exacerbates kidney injury by altering DNA methylation2023
- Author(s)
  Nakamichi Ran、Hishikawa Akihito、Chikuma Shunsuke、Yoshimura Akihiko、Sasaki Takashi、Hashiguchi Akinori、Abe Takaya、Tokuhara Tomoko、Yoshimoto Norifumi、Nishimura Erina Sugita、Hama Eriko Yoshida、Azegami Tatsuhiko、Nakayama Takashin、Hayashi Kaori、Itoh Hiroshi
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 4 Pages: 112302-112302
- DOI
  10.1016/j.celrep.2023.112302
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18270, KAKENHI-PROJECT-22K19444, KAKENHI-PROJECT-22K19446, KAKENHI-PROJECT-21H05044, KAKENHI-PROJECT-23K24114, KAKENHI-PROJECT-22K19511, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K24351
[Journal Article] Vaccination against connective tissue growth factor attenuates the development of renal fibrosis.2022
- Author(s)
  Nakayama T, Azegami T, Hayashi K, Hishikawa A, Yoshimoto N, Nakamichi R, Sugita E, Itoh H
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 10933-10933
- DOI
  10.1038/s41598-022-15118-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08263, KAKENHI-PROJECT-21K18270, KAKENHI-PROJECT-22K19511, KAKENHI-PROJECT-20H00535
[Journal Article] DNA repair factor KAT5 prevents ischemic acute kidney injury through glomerular filtration regulation2021
- Author(s)
  Akihito Hishikawa, Kaori Hayashi (corresponding author), Akiko Kubo, Kazutoshi Miyashita, Akinori Hashiguchi, Kenichiro Kinouchi, Norifumi Yoshimoto, Ran Nakamichi, Riki Akashio, Erina Sugita, Tatsuhiko Azegami, Toshiaki Monkawa, Makoto Suematsu, Hiroshi Itoh.
- Journal Title
  
  iScience.
  
  Volume: 24(12) Issue: 12 Pages: 103436-103436
- DOI
  10.1016/j.isci.2021.103436
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08688, KAKENHI-PROJECT-20H00535, KAKENHI-PROJECT-21K06876, KAKENHI-PROJECT-21K18270, KAKENHI-PROJECT-20K17291
[Presentation] 近位尿細管上皮細胞におけるDNA損傷修復は全身の代謝変容を惹起する2023
- Author(s)
  西村　絵里那、林　香、菱川　彰人、中道　蘭、吉本　憲史、吉田　英莉子、伊藤　裕
- Organizer
  第66回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-23K07705
[Presentation] DNA Double-Strand Breaks in Proximal Tubular Epithelial Cells Induce a Systemic Lipodystrophy-Like Phenotype2023
- Author(s)
  Erina Sugita Nishimura , Akihito Hishikawa, Ran Nakamichi, Eriko Yoshida Hama, Kaori Hayashi
- Organizer
  American Society of Nephrology Kidney Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07705
[Presentation] DNA修復因子KAT5を介した尿細管糸球体フィードバック制御2021
- Author(s)
  菱川彰人、林香、久保亜紀子、宮下和季、橋口明典、吉本憲史、中道蘭、杉田絵里那、赤塩理起、門川俊明、末松誠、伊藤裕
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K17291
[Presentation] 腎臓病におけるDNA損傷修復とDNA メチル化の意義について2021
- Author(s)
  菱川彰人
- Organizer
  第64回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K17291
[Presentation] DNA repair factor KAT5 acts against ischemia-reperfusion injury through promoted DNA repair and KCC3-dependent TGF regulation in proximal tubular cells2020
- Author(s)
  Akihito Hishikawa, Kaori Hayashi, Toshiaki Monkawa, Hiroshi Itoh
- Organizer
  ASN kidney week 2020
- Data Source
  KAKENHI-PROJECT-20K17291
[Presentation] AKIプレコンディショニング効果におけるDNA修復因子KAT5の役割の検討2020
- Author(s)
  菱川彰人，林香，吉本憲史，中道蘭，門川俊明，伊藤裕
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-20K17291

1. 林香 (60445294)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. 伊藤裕 (40252457)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 楠本大 (70571727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 畔上達彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hishikawa Akihito 菱川 彰人

HISHIKAWA Akihito 菱川 彰人

Research Projects

Research Products

Co-Researchers

腎臓におけるDNA損傷修復と全身代謝変容連関の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

尿中細胞の深層学習・画像解析による腎疾患早期診断方法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

血球細胞DNAメチル化をターゲットとした慢性腎臓病新規治療戦略の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulatory mechanism of anion transporter mediated by DNA repair factor in acute kidney injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Podocyte Ercc1 is indispensable for glomerular integrity2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Significance of podocyte DNA damage and glomerular DNA methylation in CKD patients with proteinuria2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Plasminogen activator inhibitor 1 is not a major causative factor for exacerbation in a mouse model of SARS-CoV-2 infection2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA-damaged podocyte-CD8 T?cell crosstalk exacerbates kidney injury by altering DNA methylation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vaccination against connective tissue growth factor attenuates the development of renal fibrosis.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA repair factor KAT5 prevents ischemic acute kidney injury through glomerular filtration regulation2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 近位尿細管上皮細胞におけるDNA損傷修復は全身の代謝変容を惹起する2023

Author(s)

Organizer

Data Source

[Presentation] DNA Double-Strand Breaks in Proximal Tubular Epithelial Cells Induce a Systemic Lipodystrophy-Like Phenotype2023

Author(s)

Organizer

Data Source

[Presentation] DNA修復因子KAT5を介した尿細管糸球体 フィードバック制御2021

Author(s)

Organizer

Data Source

[Presentation] 腎臓病におけるDNA損傷修復とDNA メチル化の意義について2021

Author(s)

Organizer

Data Source

[Presentation] DNA repair factor KAT5 acts against ischemia-reperfusion injury through promoted DNA repair and KCC3-dependent TGF regulation in proximal tubular cells2020

Author(s)

Organizer

Data Source

[Presentation] AKIプレコンディショニング効果におけるDNA修復因子KAT5の役割の検討2020

Hishikawa Akihito 菱川彰人

HISHIKAWA Akihito 菱川彰人

[Presentation] DNA修復因子KAT5を介した尿細管糸球体フィードバック制御2021