Yagai Tomoki 谷貝知樹

Researcher Number	50868669
Other IDs
Affiliation (Current)	2025: 名古屋大学, 環境医学研究所, 特任講師
Affiliation (based on the past Project Information) *help	2025: 名古屋大学, 環境医学研究所, 特任講師 2022 – 2023: 名古屋大学, 環境医学研究所, 特任講師 2020 – 2022: 東北大学, 加齢医学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 49010:Pathological biochemistry-related Except Principal Investigator Basic Section 49010:Pathological biochemistry-related
Keywords	Principal Investigator 脂肪肝 / エクソソーム / NASH / PPARa / 脂質代謝 / 肝臓 Except Principal Investigator メタボリックシンドローム / 肥満 / 代謝性疾患 / 炎症性反応 … More / マクロファージ / 炎症 / エクソソーム / エネルギー代謝性疾患 / 細胞外小胞 / 慢性炎症 Less

脂質代謝制御因子が担う肝臓における脂肪毒性産生の分子基盤解析Principal Investigator
- Principal Investigator
  
  谷貝知樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Nagoya University
The molecular basis for exosome-induced inflammatory responses
- Principal Investigator
  
  Nakamura Takahisa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Tohoku University
Analysis of anti-inflammatory effect of exosome regulated by PPARaPrincipal Investigator
- Principal Investigator
  
  Yagai Tomoki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Nagoya University
  Tohoku University

All 2022 2021

All Journal Article

[Journal Article] Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation2022
- Author(s)
  Aibara Daisuke、Takahashi Shogo、Yagai Tomoki、Kim Donghwan、Brocker Chad N.、Levi Moshe、Matsusue Kimihiko、Gonzalez Frank J.
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 5 Pages: 104196-104196
- DOI
  10.1016/j.isci.2022.104196
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16152, KAKENHI-PROJECT-21K15424
[Journal Article] Mechanistic insights into the peroxisome proliferator-activated receptor alpha as a transcriptional suppressor2022
- Author(s)
  Yagai Tomoki、Nakamura Takahisa
- Journal Title
  
  Frontiers in Medicine
  
  Volume: 9
- DOI
  10.3389/fmed.2022.1060244
- Data Source
  KAKENHI-PROJECT-20K16152
[Journal Article] FXR-Deoxycholic Acid-TNF-α Axis Modulates Acetaminophen-Induced Hepatotoxicity2021
- Author(s)
  Yan Tingting、Yan Nana、Wang Hong、Yagai Tomoki、Luo Yuhong、Takahashi Shogo、Zhao Min、Krausz Kristopher W、Wang Guangji、Hao Haiping、Gonzalez Frank J
- Journal Title
  
  Toxicological Sciences
  
  Volume: 181 Issue: 2 Pages: 273-284
- DOI
  10.1093/toxsci/kfab027
- Data Source
  KAKENHI-PROJECT-20K16152
[Journal Article] YAP‐TEAD mediates PPAR α?induced hepatomegaly and liver regeneration in mice2021
- Author(s)
  Fan Shicheng、Gao Yue、Qu Aijuan、Jiang Yiming、Li Hua、Xie Guomin、Yao Xinpeng、Yang Xiao、Zhu Shuguang、Yagai Tomoki、Tian Jianing、Wang Ruimin、Gonzalez Frank J.、Huang Min、Bi Huichang
- Journal Title
  
  Hepatology
  
  Volume: 75 Issue: 1 Pages: 74-88
- DOI
  10.1002/hep.32105
- Data Source
  KAKENHI-PROJECT-20K16152
[Journal Article] Feedback repression of PPARα signaling by Let-7 microRNA2021
- Author(s)
  Yagai Tomoki、Yan Tingting、Luo Yuhong、Takahashi Shogo、Aibara Daisuke、Kim Donghwan、Brocker Chad N.、Levi Moshe、Motohashi Hozumi、Gonzalez Frank J.
- Journal Title
  
  Cell Reports
  
  Volume: 36 Issue: 6 Pages: 109506-109506
- DOI
  10.1016/j.celrep.2021.109506
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16152, KAKENHI-PROJECT-21K15424

1. Nakamura Takahisa (30396874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 本橋ほづみ (00282351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 北村大志 (20706949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yagai Tomoki 谷貝 知樹

Research Projects

Research Products

Co-Researchers

脂質代謝制御因子が担う肝臓における脂肪毒性産生の分子基盤解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The molecular basis for exosome-induced inflammatory responses

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of anti-inflammatory effect of exosome regulated by PPARaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanistic insights into the peroxisome proliferator-activated receptor alpha as a transcriptional suppressor2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] FXR-Deoxycholic Acid-TNF-α Axis Modulates Acetaminophen-Induced Hepatotoxicity2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] YAP‐TEAD mediates PPAR α?induced hepatomegaly and liver regeneration in mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Feedback repression of PPARα signaling by Let-7 microRNA2021

Author(s)

Journal Title

DOI

Data Source

Yagai Tomoki 谷貝知樹