Yoshioka Hiromasa 吉岡広大

… Alternative Names

吉岡広大ヨシオカヒロマサ

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Researcher Number	50878402
Other IDs	https://orcid.org/0000-0002-9281-9982
Affiliation (Current)	2026: 東京科学大学, 総合研究院, 助教 2026: 国立研究開発法人理化学研究所, 開拓研究所, 基礎科学特別研究員
Affiliation (based on the past Project Information) *help	2026: 国立研究開発法人理化学研究所, 開拓研究所, 基礎科学特別研究員 2024: 国立研究開発法人理化学研究所, 開拓研究本部, 基礎科学特別研究員 2023: 国立研究開発法人理化学研究所, 開拓研究本部, 特別研究員
Review Section/Research Field	Principal Investigator Basic Section 37030:Chemical biology-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Keywords	Principal Investigator 組織特異性 / タンパク質安定性 / コレステロール合成 / メタセシス / 人工金属酵素 / プロドラッグ / タンパク質分解 / フィードバック / コレステロール合成酵素 / PROTAC / SQLE

タンパク質の局在を移行する新規抗がん剤の創製Principal Investigator
- Principal Investigator
  
  吉岡広大
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Institute of Physical and Chemical Research
Development of tissue-specific methods controlling protein stabilityPrincipal Investigator
- Principal Investigator
  
  吉岡広大
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Institute of Physical and Chemical Research

All 2024 2023

All Journal Article Presentation

[Journal Article] Anticancer approach by targeted activation of a global inhibitor of sialyltransferases with acrolein2024
- Author(s)
  Kasahara Takatsugu、Chang Tsung-Che、Yoshioka Hiromasa、Urano Sayaka、Egawa Yasuko、Inoue Michiko、Tahara Tsuyoshi、Koji Morimoto、Pradipta Ambara R.、Tanaka Katsunori
- Journal Title
  
  Chemical Science
  
  Volume: - Issue: 25 Pages: 9566-9573
- DOI
  10.1039/d4sc00969j
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05269, KAKENHI-PROJECT-24H00491, KAKENHI-PROJECT-24K08629, KAKENHI-PROJECT-23K17971, KAKENHI-PROJECT-23K14331
[Journal Article] Catalytic olefin metathesis in blood2023
- Author(s)
  Nasibullin Igor、Yoshioka Hiromasa、Mukaimine Akari、Nakamura Akiko、Kusakari Yuriko、Chang Tsung-Che、Tanaka Katsunori
- Journal Title
  
  Chemical Science
  
  Volume: 14 Issue: 40 Pages: 11033-11039
- DOI
  10.1039/d3sc03785a
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14331, KAKENHI-PROJECT-21K05302
[Presentation] Anticancer approach by targeted activation of a global inhibitor of sialyltransferases with acrolein2024
- Author(s)
  張宗哲、笠原隆継、吉岡広大、浦野清香、江河泰子、井上美智子、田原強、盛本浩二、Ambara R. Pradipta、田中克典
- Organizer
  第43回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-23K14331
[Presentation] Selective Activation of PROTACs in Cancer Cells via Metathesis Reaction using Artificial Metalloenzymes2024
- Author(s)
  Yuta Shimura, Hiromasa Yoshioka, Ambara R. Pradipta, Katsunori Tanaka
- Organizer
  1st Biology and Chemistry Cancer and Aging Research Symposium (BioCARES)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14331
[Presentation] Catalytic olefin metathesis in blood2023
- Author(s)
  張宗哲 , ナシブリンイゴール , 吉岡広大 , 向峯あかり , 田中克典
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-23K14331

1. PRADIPTA AMBARA

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yoshioka Hiromasa 吉岡広大

吉岡広大ヨシオカヒロマサ

Research Projects

Research Products

Co-Researchers

タンパク質の局在を移行する新規抗がん剤の創製Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of tissue-specific methods controlling protein stabilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Anticancer approach by targeted activation of a global inhibitor of sialyltransferases with acrolein2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Catalytic olefin metathesis in blood2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] Anticancer approach by targeted activation of a global inhibitor of sialyltransferases with acrolein2024

Author(s)

Organizer

Data Source

[Presentation] Selective Activation of PROTACs in Cancer Cells via Metathesis Reaction using Artificial Metalloenzymes2024

Author(s)

Organizer

Data Source

[Presentation] Catalytic olefin metathesis in blood2023

Author(s)

Organizer

Data Source

Yoshioka Hiromasa 吉岡 広大

吉岡 広大 ヨシオカ ヒロマサ

Research Projects

Research Products

Co-Researchers

タンパク質の局在を移行する新規抗がん剤の創製Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of tissue-specific methods controlling protein stabilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Anticancer approach by targeted activation of a global inhibitor of sialyltransferases with acrolein2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Catalytic olefin metathesis in blood2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] Anticancer approach by targeted activation of a global inhibitor of sialyltransferases with acrolein2024

Author(s)

Organizer

Data Source

[Presentation] Selective Activation of PROTACs in Cancer Cells via Metathesis Reaction using Artificial Metalloenzymes2024

Author(s)

Organizer

Data Source

[Presentation] Catalytic olefin metathesis in blood2023

Author(s)

Organizer

Data Source

Yoshioka Hiromasa 吉岡広大

吉岡広大ヨシオカヒロマサ