Kawai Hitomi 河合瞳

Researcher Number	50895026
Other IDs
Affiliation (Current)	2026: 筑波大学, 医学医療系, 助教
Affiliation (based on the past Project Information) *help	2026: 筑波大学, 医学医療系, 助教 2022 – 2024: 筑波大学, 医学医療系, 助教 2021: 筑波大学, 附属病院, 病院講師
Review Section/Research Field	Principal Investigator Basic Section 49020:Human pathology-related
Keywords	Principal Investigator 薬剤抵抗性 / 胃腸上皮マーカー / MRP2 / A549 / 胃腸上皮形質 / non-TRU type / HNF4α / non-TRU / 肺腺癌 / 免疫組織化学 … More / 質量分析 / 免疫沈降 / 接着因子 / 遠隔転移 / 免疫染色 / 浸潤性粘液性腺癌 / モノクローナル抗体 / 細胞膜タンパク / 浸潤性粘液腺癌 Less

AIを活用した肺腺癌の空間トランスクリプトーム解析Principal Investigator
- Principal Investigator
  
  河合瞳
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  University of Tsukuba
Research for the expression of gastrointestinal marker in lung adenocarcinomas and the relationship between drug resistance and the gastrointestinal features in lung adenocarcinomaPrincipal Investigator
- Principal Investigator
  
  Kawai Hitomi
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  University of Tsukuba
Research for cell-basement membrane adhesion factors involved in distant metastasis of tumors using human tumor tissue.Principal Investigator
- Principal Investigator
  
  Kawai Hitomi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  University of Tsukuba

All 2024 2023 2022 2021 Other

All Journal Article Presentation Other

[Journal Article] Expression patterns of HNF4α, TTF-1, and SMARCA4 in lung adenocarcinomas: impacts on clinicopathological and genetic features2024
- Author(s)
  Kawai Hitomi、Miura Tamaki、Kawamatsu Natsumi、Nakagawa Tomoki、Shiba-Ishii Aya、Yoshimoto Taichiro、Amano Yusuke、Kihara Atsushi、Sakuma Yuji、Fujita Kazutaka、Shibano Tomoki、Ishikawa Shumpei、Ushiku Tetsuo、Fukayama Masashi、Tsubochi Hiroyoshi、Endo Shunsuke、Hagiwara Koichi、Matsubara Daisuke、Niki Toshiro
- Journal Title
  
  Virchows Archiv
  
  Volume: 486 Issue: 2 Pages: 343-354
- DOI
  10.1007/s00428-024-03816-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24102, KAKENHI-PROJECT-20K07378, KAKENHI-PROJECT-23K14469, KAKENHI-PROJECT-22K06945, KAKENHI-PROJECT-22K15412
[Journal Article] Histologic transformation of non‐small‐cell lung cancer in response to tyrosine kinase inhibitors: Current knowledge of genetic changes and molecular mechanisms2024
- Author(s)
  Shiba‐Ishii Aya、Takemura Noriko、Kawai Hitomi、Matsubara Daisuke
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 7 Pages: 2138-2146
- DOI
  10.1111/cas.16192
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24102, KAKENHI-PROJECT-23K14469
[Journal Article] Whole-genome sequencing reveals the molecular implications of the stepwise progression of lung adenocarcinoma2023
- Author(s)
  Haga Y, Sakamoto Y, Kajiya K, Kawai H, Oka M, Motoi N, Shirasawa M, Yotsukura M, Watanabe S, Arai M, Zenkoh J, Shiraishi K, Seki M, Kanai A, Shiraishi Y, Yatabe Y, Matsubara D, Suzuki Y, Noguchi M, Kohno T, Suzuki A.
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 8375-8375
- DOI
  10.1038/s41467-023-43732-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14469, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H00545, KAKENHI-PROJECT-23K27389, KAKENHI-PROJECT-23K27449, KAKENHI-PROJECT-23K24102
[Journal Article] Molecular Subtypes of High-Grade Neuroendocrine Carcinoma (HGNEC): What is YAP1-Positive HGNEC?2022
- Author(s)
  Kawai Hitomi、Matsuoka Ryouta、Ito Takeshi、Matsubara Daisuke
- Journal Title
  
  Frontiers in Bioscience-Landmark
  
  Volume: 27 Issue: 3 Pages: 108-108
- DOI
  10.31083/j.fbl2703108
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07441, KAKENHI-PROJECT-21K07091, KAKENHI-PROJECT-22K15418, KAKENHI-PROJECT-21K15381
[Journal Article] Aberrant OCIAD2 demethylation in lung adenocarcinoma is associated with outcome2022
- Author(s)
  Masahiro Maki, Hong JeongMin, Tomoki Nakagawa, Hitomi Kawai, Noriaki Sakamoto, Yukio Sato, Masayuki Noguchi
- Journal Title
  
  Pathology International
  
  Volume: 10 Issue: 10 Pages: 496-505
- DOI
  10.1111/pin.13262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15381
[Journal Article] Gene expression profiles of the original tumors influence the generation of PDX models of lung squamous cell carcinoma2021
- Author(s)
  Yunjung Kim, Aya Shiba-Ishii, Tomoki Nakagawa, Tomoyo Takeuchi, Hitomi Kawai, Ryota Matsuoka, Masayuki Noguchi, Noriaki Sakamoto
- Journal Title
  
  Laboratory Investigation
  
  Volume: 101(5) Issue: 5 Pages: 523-553
- DOI
  10.1038/s41374-021-00529-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15381
[Presentation] The AI diagnosis for lung adenocarcinoma invasion based on the prognostic histological feature2024
- Author(s)
  Hitomi Kawai, Yasushi Yatabe, Akihiko Yoshizawa, Yasuhiro Sakai, Motoharu Okawa, Kazuhiro Hotta, Masayuki Noguchi, Daisuke Matsubara
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K14469
[Presentation] Update in the AI Diagnosis for Lung Adenocarcinoma Invasion2023
- Author(s)
  Hitomi Kawai, Yasushi Yatabe, Akihiko Yoshizawa, Yasuhiro Sakai, Motoharu Ohkawa, Kazuhiro Hotta, Masayuki Noguchi, Daisuke Matsubara
- Organizer
  The 7th Asia-Australasia Pulmonary Pathology Society Annual Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14469
[Presentation] HNF4a陽性の高悪性度肺腺癌は、BRG1欠失を高頻度に示す予後不良な一群である2023
- Author(s)
  河合瞳、三浦珠希、川松夏実、中川智貴、柴綾、石川俊平、坪地宏嘉、萩原弘一、松原大祐、仁木仁郎
- Organizer
  第112回病理学会
- Data Source
  KAKENHI-PROJECT-23K14469
[Presentation] AIは“肺腺癌の浸潤”をどう判定するか？2022
- Author(s)
  河合瞳、吉澤明彦、谷田部恭、酒井康弘、大川元春、堀田一弘、野口雅之、松原大祐
- Organizer
  第62回日本肺癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15381
[Presentation] AIによる肺腺癌の浸潤部の判定：AIは組織学的な予後因子を抽出できるか？2022
- Author(s)
  河合瞳、吉澤明彦、谷田部恭、酒井康弘、大川元春、堀田一弘、野口雅之、松原大祐
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K15381
[Presentation] Development of AI diagnosis for the invasion of lung adenocarcinoma; Can AI predict the prognosis?2022
- Author(s)
  河合瞳、吉澤明彦、谷田部恭、酒井康弘、大川元春、堀田一弘、野口雅之、松原大祐
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15381
[Presentation] AI は“肺腺癌の浸潤”をどう判定するか？2021
- Author(s)
  河合瞳, 吉澤明彦, 谷田部恭, 酒井康裕, 大川元春, 堀田一弘, 野口雅之
- Organizer
  第62回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15381
[]

1. MATSYBARA Daisuk

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. 柴綾

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 伊東剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Kawai Hitomi 河合 瞳

Research Projects

Research Products

Co-Researchers

AIを活用した肺腺癌の空間トランスクリプトーム解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research for the expression of gastrointestinal marker in lung adenocarcinomas and the relationship between drug resistance and the gastrointestinal features in lung adenocarcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research for cell-basement membrane adhesion factors involved in distant metastasis of tumors using human tumor tissue.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Expression patterns of HNF4α, TTF-1, and SMARCA4 in lung adenocarcinomas: impacts on clinicopathological and genetic features2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Histologic transformation of non‐small‐cell lung cancer in response to tyrosine kinase inhibitors: Current knowledge of genetic changes and molecular mechanisms2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Whole-genome sequencing reveals the molecular implications of the stepwise progression of lung adenocarcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular Subtypes of High-Grade Neuroendocrine Carcinoma (HGNEC): What is YAP1-Positive HGNEC?2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aberrant OCIAD2 demethylation in lung adenocarcinoma is associated with outcome2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene expression profiles of the original tumors influence the generation of PDX models of lung squamous cell carcinoma2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] The AI diagnosis for lung adenocarcinoma invasion based on the prognostic histological feature2024

Author(s)

Organizer

Data Source

[Presentation] Update in the AI Diagnosis for Lung Adenocarcinoma Invasion2023

Author(s)

Organizer

Data Source

[Presentation] HNF4a陽性の高悪性度肺腺癌は、BRG1欠失を高頻度に示す予後不良な一群である2023

Author(s)

Organizer

Data Source

[Presentation] AIは“肺腺癌の浸潤”をどう判定するか？2022

Author(s)

Organizer

Data Source

[Presentation] AIによる肺腺癌の浸潤部の判定：AIは組織学的な予後因子を抽出できるか？2022

Author(s)

Organizer

Data Source

[Presentation] Development of AI diagnosis for the invasion of lung adenocarcinoma; Can AI predict the prognosis?2022

Author(s)

Organizer

Data Source

[Presentation] AI は“肺腺癌の浸潤”をどう判定するか？2021

Author(s)

Organizer

Data Source

Kawai Hitomi 河合瞳