Murakami Takaaki 村上隆亮

Researcher Number	50904017
Other IDs
Affiliation (Current)	2026: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 京都大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related / Basic Section 54040:Metabolism and endocrinology-related / 0904:Internal medicine of the bio-information integration and related fields
Keywords	Principal Investigator 膵β細胞 / 分子イメージング / GLP-1受容体 / 糖尿病 / 小胞体ストレス / 膵β細胞量 / 中枢神経系 / イメージング

非侵襲的膵β細胞イメージングによる縦断的膵β細胞量評価法Principal Investigator
- Principal Investigator
  
  村上隆亮
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kyoto University
Molecular mechanisms of pancreatic beta cell proliferarion via endoplasmic reticulum stress responsesPrincipal Investigator
- Principal Investigator
  
  Murakami Takaaki
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kyoto University
Noninvasive evaluation of GLP-1 receptor in central nervous systemPrincipal Investigator
- Principal Investigator
  
  Murakami Takaaki
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0904:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kyoto University

All 2025 2024 2023 2022

All Journal Article

[Journal Article] Voltage-gated calcium channel α2δ-1 subunit is involved in the regulation of glucose-stimulated GLP-1 secretion in mice2025
- Author(s)
 Yang Yuhan、Yamane Shunsuke、Harada Norio、Ikeguchi-Ogura Eri、Yamamoto Kana、Wada Naoki、Fauzi Muhammad、Murakami Takaaki、Yabe Daisuke、Hayashi Yoshitaka、Inagaki Nobuya
- Journal Title
 
 American Journal of Physiology-Gastrointestinal and Liver Physiology
 
 Volume: 328 Issue: 3 Pages: 243-251
- DOI
 10.1152/ajpgi.00279.2024
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-22K08652, KAKENHI-PROJECT-22K08668, KAKENHI-PROJECT-23K24765, KAKENHI-PROJECT-24K02359, KAKENHI-PROJECT-24K11712, KAKENHI-PROJECT-24K19286
[Journal Article] Disruption of insulin receptor substrate 2 (IRS2) causes non-obese type 2 diabetes with β-cell dysfunction in the golden (Syrian) hamster2024
- Author(s)
  Hirose Michiko、Inoue Kimiko、Matoba Shogo、Tatebe Takaki、Tokita Syun、Dodo Yukiko、Tomishima Toshiko、Hasegawa Ayumi、Honda Arata、Ozaki Mao、Shinogi Akiko、Yanagisawa Ryoko、Fauzi Muhammad、Murakami Takaaki、Inagaki Nobuya、Tamura Masaru、Ogura Atsuo
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 17450-17450
- DOI
  10.1038/s41598-024-67513-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K20298, KAKENHI-PROJECT-23K27096, KAKENHI-PROJECT-24K02359, KAKENHI-PROJECT-24K11712, KAKENHI-PROJECT-24K21266
[Journal Article] [18F]FB(ePEG12)12-exendin-4 noninvasive imaging of insulinoma negative for insulin immunostaining on specimen from endoscopic ultrasonography-guided fine needle aspiration: a case report with review of literature2024
- Author(s)
 Otani Daisuke、Murakami Takaaki、Murakami Saeko、Hanaoka Ikuko、Fujimoto Hiroyuki、Shimizu Yoichi、Kawai Miyake Kanae、Sakaki Kentaro、Ueda Yohei、Tanaka Daisuke、Ohno Tsuyoshi、Shimizu Hironori、Uyama Naoki、Iizuka Norishige、Yabe Daisuke、Nakamoto Yuji、Inagaki Nobuya
- Journal Title
 
 Endocr J
 
 Volume: 71 Issue: 9 Pages: 925-933
- DOI
 10.1507/endocrj.EJ24-0187
- ISSN
 0918-8959, 1348-4540
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-24K02359, KAKENHI-PROJECT-24K11694
[Journal Article] State-of-the-Art Hybrid Imaging of Neuroendocrine Neoplasms2024
- Author(s)
  Ambrosini Valentina、Fortunati Emilia、Fanti Stefano、Ursprung Stephan、Asmundo Luigi、O'Shea Aileen、Kako Bashar、Lee Susanna、Furtado Felipe S.、Blake Michael、Goiffon Reece J.、Najmi Zahra、Hesami Mina、Murakami Takaaki、Domachevsky Liran、Catalano Onofrio A.
- Journal Title
  
  Journal of Computer Assisted Tomography
  
  Volume: 48 Issue: 4 Pages: 510-520
- DOI
  10.1097/rct.0000000000001594
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K02359
[Journal Article] Elevated serum growth differentiation factor 15 levels as a potential biomarker of the efficacy of imeglimin in individuals with type 2 diabetes mellitus: an exploratory study.2024
- Author(s)
  Wada N, Murakami T, Fauzi M, Sakaki K, Oshima S, Shimada Y, Asai K, Oshima A, Nomura S, Joo E, Mori M, Fujiwara R, Shide K, Wada K, Yabe D, Inagaki N, Harada N.
- Journal Title
  
  J Clin Med Res.
  
  Volume: 16 Issue: 10 Pages: 503-508
- DOI
  10.14740/jocmr6031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08668, KAKENHI-PROJECT-23K28017, KAKENHI-PROJECT-24K02359, KAKENHI-PROJECT-24K11712
[Journal Article] Impact of Prevascularization on Immunological Environment and Early Engraftment in Subcutaneous Islet Transplantation2024
- Author(s)
  Inoguchi Kenta、Anazawa Takayuki、Fujimoto Nanae、Tada Seiichiro、Yamane Kei、Emoto Norio、Izuwa Aya、Su Hang、Fujimoto Hiroyuki、Murakami Takaaki、Nagai Kazuyuki、Hatano Etsuro
- Journal Title
  
  Transplantation
  
  Volume: - Issue: 5 Pages: 1115-1126
- DOI
  10.1097/tp.0000000000004909
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16411, KAKENHI-PROJECT-23K21446, KAKENHI-PROJECT-24K02359
[Journal Article] Unmasked insulinoma occasioned by severe hypoglycemic coma immediately postpartum: a case report2023
- Author(s)
  Matsumoto Kiyoshi、Watanabe Miyu、Takao Ken、Takahashi Hirokazu、Daido Hisashi、Shibata Toshiro、Hirose Tokuyuki、Kato Takehiro、Mizuno Masami、Hirota Takuo、Suwa Tetsuya、Horikawa Yukio、Murakami Takaaki、Yabe Daisuke
- Journal Title
  
  BMC Endocrine Disorders
  
  Volume: 23 Issue: 1 Pages: 168-168
- DOI
  10.1186/s12902-023-01415-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16411, KAKENHI-PROJECT-23K28017
[Journal Article] 18F-labeled PEGylated exendin-4 imaging noninvasively differentiates insulinoma from an accessory spleen: the first case report of [18F]FB(ePEG12)12-exendin-4 positron emission tomography/computed tomography for insulinoma2023
- Author(s)
  Sakaki Kentaro、Murakami Takaaki、Fujimoto Hiroyuki、Shimizu Yoichi、Miyake Kanae Kawai、Otani Daisuke、Kiyobayashi Sakura、Okada Takuya、Fujimoto Masakazu、Hakata Takuro、Yamauchi Ichiro、Shimada Kotaro、Shimizu Hironori、Nagai Kazuyuki、Nakamoto Yuji、Inagaki Nobuya
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 14
- DOI
  10.3389/fendo.2023.1245573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08553, KAKENHI-PROJECT-22K16411
[Journal Article] Noninvasive evaluation of donor and native pancreases following simultaneous pancreas?kidney transplantation using positron emission tomography/computed tomography2023
- Author(s)
  Murakami Takaaki、Nakamura Toshihiro、Fujimoto Hiroyuki、Fujikura Junji、Shimizu Yoichi、Miyake Kanae K.、Otani Daisuke、Sakaki Kentaro、Kiyobayashi Sakura、Anazawa Takayuki、Nakamoto Yuji、Inagaki Nobuya
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 14 Issue: 10 Pages: 1187-1191
- DOI
  10.1111/jdi.14045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08553, KAKENHI-PROJECT-21K06970, KAKENHI-PROJECT-22K16411
[Journal Article] Noninvasive quantitative evaluation of viable islet grafts using <scp> 111 In </scp> ‐exendin‐4 <scp>SPECT</scp> / <scp>CT</scp>2023
- Author(s)
 Botagarova Ainur、Murakami Takaaki、Fujimoto Hiroyuki、Fauzi Muhammad、Kiyobayashi Sakura、Otani Daisuke、Fujimoto Nanae、Inagaki Nobuya
- Journal Title
 
 The FASEB Journal
 
 Volume: 37 Issue: 4 Pages: 1-11
- DOI
 10.1096/fj.202201787rr
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21K08553, KAKENHI-PROJECT-22K16411, KAKENHI-PROJECT-21K20931
[Journal Article] Preservation effect of imeglimin on pancreatic β-cell mass: Noninvasive evaluation using 111In-exendin-4 SPECT/CT imaging and the perspective of mitochondrial involvements2022
- Author(s)
  Fauzi Muhammad、Murakami Takaaki、Fujimoto Hiroyuki、Botagarova Ainur、Sakaki Kentaro、Kiyobayashi Sakura、Ogura Masahito、Inagaki Nobuya
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 13 Pages: 1-12
- DOI
  10.3389/fendo.2022.1010825
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08553, KAKENHI-PROJECT-22K16411, KAKENHI-PROJECT-21K20931
[Journal Article] Noninvasive Evaluation of GIP Effects on β-Cell Mass Under High-Fat Diet2022
- Author(s)
  Kiyobayashi Sakura、Murakami Takaaki、Harada Norio、Fujimoto Hiroyuki、Murata Yuki、Fujita Naotaka、Hamamatsu Keita、Ikeguchi-Ogura Eri、Hatoko Tomonobu、Lu Xuejing、Yamane Shunsuke、Inagaki Nobuya
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 13 Pages: 1-11
- DOI
  10.3389/fendo.2022.921125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08553, KAKENHI-PROJECT-22K08668, KAKENHI-PROJECT-21K20931
[Journal Article] Current understanding of imeglimin action on pancreatic β‐cells: Involvement of mitochondria and endoplasmic reticulum homeostasis2022
- Author(s)
  Fauzi Muhammad、Murakami Takaaki、Yabe Daisuke、Inagaki Nobuya
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 14 Issue: 2 Pages: 186-188
- DOI
  10.1111/jdi.13951
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16411

1. 中本裕士 (20360844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 藤本裕之 (50437274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 河井可奈江 (60812641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 志水陽一 (90634212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MATOBA Shogo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. HARADA Norio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 山根俊介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Murakami Takaaki 村上 隆亮

Research Projects

Research Products

Co-Researchers

非侵襲的膵β細胞イメージングによる縦断的膵β細胞量評価法Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of pancreatic beta cell proliferarion via endoplasmic reticulum stress responsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Noninvasive evaluation of GLP-1 receptor in central nervous systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Voltage-gated calcium channel α<sub>2</sub>δ-1 subunit is involved in the regulation of glucose-stimulated GLP-1 secretion in mice2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Disruption of insulin receptor substrate 2 (IRS2) causes non-obese type 2 diabetes with β-cell dysfunction in the golden (Syrian) hamster2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] [<sup>18</sup>F]FB(ePEG12)12-exendin-4 noninvasive imaging of insulinoma negative for insulin immunostaining on specimen from endoscopic ultrasonography-guided fine needle aspiration: a case report with review of literature2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] State-of-the-Art Hybrid Imaging of Neuroendocrine Neoplasms2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elevated serum growth differentiation factor 15 levels as a potential biomarker of the efficacy of imeglimin in individuals with type 2 diabetes mellitus: an exploratory study.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of Prevascularization on Immunological Environment and Early Engraftment in Subcutaneous Islet Transplantation2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unmasked insulinoma occasioned by severe hypoglycemic coma immediately postpartum: a case report2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 18F-labeled PEGylated exendin-4 imaging noninvasively differentiates insulinoma from an accessory spleen: the first case report of [18F]FB(ePEG12)12-exendin-4 positron emission tomography/computed tomography for insulinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Noninvasive evaluation of donor and native pancreases following simultaneous pancreas?kidney transplantation using positron emission tomography/computed tomography2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Noninvasive quantitative evaluation of viable islet grafts using <scp> <sup>111</sup> In </scp> ‐exendin‐4 <scp>SPECT</scp> / <scp>CT</scp>2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preservation effect of imeglimin on pancreatic β-cell mass: Noninvasive evaluation using 111In-exendin-4 SPECT/CT imaging and the perspective of mitochondrial involvements2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Noninvasive Evaluation of GIP Effects on β-Cell Mass Under High-Fat Diet2022

Murakami Takaaki 村上隆亮