Afroj Tania ＡｆｒｏｊＴａｎｉａ

Researcher Number	50913034
Other IDs
Affiliation (Current)	2026: 島根大学, 医学部, 特別協力研究員 2026: 神戸大学, 医学系研究科(医), 医学研究員
Affiliation (based on the past Project Information) *help	2026: 島根大学, 医学部, 特別協力研究員 2022 – 2024: 神戸大学, 医学研究科, 学術研究員
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / Basic Section 50010:Tumor biology-related / Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator Humanized mice / cancer immunotherapy / macrophages / ADCP / Renal Cell carcinoma / Human Macrophages / anti-SIRPα antibody / Xenograft model / Clonal hematopoiesis / Aging … More / Hematopoietic stem cells / CHIP / aging / Hematopoietic stem cell / Humanized mouse model / Trained immunity Less

Preclinical evaluation of a novel cancer immunotherapy against renal cell carcinoma in humanized mouse modelsPrincipal Investigator
- Principal Investigator
  
  Afroj Tania
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Shimane University
Development of a novel cancer immunotherapy model targeting human macrophagesPrincipal Investigator
- Principal Investigator
  
  Afroj Tania
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kobe University
Deciphering regulatory mechanism of trained immunity in aged HSCs and clonal hematopoiesis of indeterminate potential (CHIP)Principal Investigator
- Principal Investigator
  
  Afroj Tania
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kobe University

All 2025 2024 2023 2022

All Journal Article Presentation

[Journal Article] Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade2023
- Author(s)
  Mitsuhashi Atsushi、Koyama Kazuya、Ogino Hirokazu、Afroj Tania、Nguyen Na Thi、Yoneda Hiroto、Otsuka Kenji、Sugimoto Masamichi、Kondoh Osamu、Nokihara Hiroshi、Hanibuchi Masaki、Takizawa Hiromitsu、Shinohara Tsutomu、Nishioka Yasuhiko
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 3 Pages: 112162-112162
- DOI
  10.1016/j.celrep.2023.112162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08542, KAKENHI-PROJECT-23K24340, KAKENHI-PROJECT-22K16302
[Journal Article] Preclinical evaluation of the efficacy of an antibody to human SIRPα for cancer immunotherapy in humanized mouse models2023
- Author(s)
  Saito Yasuyuki、Iida-Norita Rie、Afroj Tania、Refaat Alaa、Hazama Daisuke、Komori Satomi、Ohata Shinya、Takai Tomoko、Oduori Okechi S.、Kotani Takenori、Funakoshi Yohei、Koma Yu-Ichiro、Murata Yoji、Yakushijin Kimikazu、Matsuoka Hiroshi、Minami Hironobu、Yokozaki Hiroshi、Manz Markus G.、Matozaki Takashi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1294814-1294814
- DOI
  10.3389/fimmu.2023.1294814
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06926, KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-22K19458, KAKENHI-PROJECT-22K15494, KAKENHI-PROJECT-22K16302, KAKENHI-PROJECT-22KF0254, KAKENHI-PROJECT-21H04807
[Journal Article] CD47 promotes peripheral T cell survival by preventing dendritic cell?mediated T cell necroptosis2023
- Author(s)
  Komori Satomi、Saito Yasuyuki、Nishimura Taichi、Respatika Datu、Endoh Hiromi、Yoshida Hiroki、Sugihara Risa、Iida-Norita Rie、Afroj Tania、Takai Tomoko、Oduori Okechi S.、Nitta Eriko、Kotani Takenori、Murata Yoji、Kaneko Yoriaki、Nitta Ryo、Ohnishi Hiroshi、Matozaki Takashi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 33 Pages: 1-1
- DOI
  10.1073/pnas.2304943120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06926, KAKENHI-PROJECT-22K08504, KAKENHI-PROJECT-21K08416, KAKENHI-PROJECT-22K19458, KAKENHI-PROJECT-22K15494, KAKENHI-PROJECT-22K16302, KAKENHI-PROJECT-22KF0254, KAKENHI-PLANNED-21H05254, KAKENHI-PROJECT-21H04807, KAKENHI-PROJECT-23K24057
[Presentation] Anti-human SIRPα antibody to target human macrophages in cancer immunotherapy2025
- Author(s)
  Tania Afroj, Satomi Komori, Ikumi Katano, Takeshi Takahashi, Takenori Kotani, Yoji Murata, Takashi Matozaki, and Yasuyuki Saito
- Organizer
  The 22nd Takeda Science Foundation Symposium on Bioscience
- Data Source
  KAKENHI-PROJECT-24K18516
[Presentation] Development of an anti-SIRPα antibody cancer immunotherapy model targeting human macrophages2024
- Author(s)
  Tania Afroj, Yasuyuki Saito, Satomi Komori, Tomoko Takai, Okechi S. Oduori, Takenori Kotani, Yoji Murata, and Takashi Matozaki
- Organizer
  83rd Annual Meeting of Japanese Cancer society
- Data Source
  KAKENHI-PROJECT-24K18516
[Presentation] Anti-tumor effect of a human SIRPα antibody targeting human macrophages in a humanized mouse model2024
- Author(s)
  Tania Afroj, Satomi Komori, Ikumi Katano, Takeshi Takahashi, Takenori Kotani, Yoji Murata, Takashi Matozaki, and Yasuyuki Saito
- Organizer
  53rd Annual Meeting of Japanese Society for immunology
- Data Source
  KAKENHI-PROJECT-24K18516
[Presentation] Preclinical evaluation of the anti-tumor effect of anti-human SIRPα antibody in a novel humanized mouse model2023
- Author(s)
  Tania Afroj, Yasuyuki Saito, Rie Iida-Norita, Satomi Komori, Takenori Kotani, Yoji Murata, Takashi Matozaki
- Organizer
  The 4th RIKEN BDR-Kobe University Joint symposium
- Data Source
  KAKENHI-PROJECT-22K16302
[Presentation] Development of a novel cancer immunotherapy model targeting human macrophages2023
- Author(s)
  Tania Afroj, Yasuyuki Saito, Satomi Komori, Tomoko Takai, Okechi S. Oduori, Takenori Kotani, Yoji Murata, and Takashi Matozaki
- Organizer
  第21回生体機能研究会
- Data Source
  KAKENHI-PROJECT-22K16302
[Presentation] Preclinical evaluation of macrophage-mediated anti-tumor effect by using a humanized MITRG mouse model2022
- Author(s)
  Yasuyuki Saito, Tania Afroj, Rie Iida-Norita, Satomi Komori, Takenori Kotani, Yoji Murata, Markus G Manz, Takashi Matozaki
- Organizer
  The 6th International Workshop on Humanized Mice (IWHM6)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16302

1. MURATA Yoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 三橋惇志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 軒原浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Afroj Tania Ａｆｒｏｊ Ｔａｎｉａ

Research Projects

Research Products

Co-Researchers

Preclinical evaluation of a novel cancer immunotherapy against renal cell carcinoma in humanized mouse modelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel cancer immunotherapy model targeting human macrophagesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Deciphering regulatory mechanism of trained immunity in aged HSCs and clonal hematopoiesis of indeterminate potential (CHIP)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preclinical evaluation of the efficacy of an antibody to human SIRPα for cancer immunotherapy in humanized mouse models2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD47 promotes peripheral T cell survival by preventing dendritic cell?mediated T cell necroptosis2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] Anti-human SIRPα antibody to target human macrophages in cancer immunotherapy2025

Author(s)

Organizer

Data Source

[Presentation] Development of an anti-SIRPα antibody cancer immunotherapy model targeting human macrophages2024

Author(s)

Organizer

Data Source

[Presentation] Anti-tumor effect of a human SIRPα antibody targeting human macrophages in a humanized mouse model2024

Author(s)

Organizer

Data Source

[Presentation] Preclinical evaluation of the anti-tumor effect of anti-human SIRPα antibody in a novel humanized mouse model2023

Author(s)

Organizer

Data Source

[Presentation] Development of a novel cancer immunotherapy model targeting human macrophages2023

Author(s)

Organizer

Data Source

[Presentation] Preclinical evaluation of macrophage-mediated anti-tumor effect by using a humanized MITRG mouse model2022

Author(s)

Organizer

Data Source

Afroj Tania ＡｆｒｏｊＴａｎｉａ