KAI Hidenori 甲斐英則

Researcher Number	60023412
External Links
Affiliation (based on the past Project Information) *help	2004 – 2008: 鳥取大学, 農学部, 教授 2000 – 2001: 鳥取大学, 農学部, 教授 1994 – 1998: 鳥取大学, 農学部, 教授 1990 – 1991: 鳥取大学, 農学部, 教授 1988: 鳥取大学, 農学部, 教授 1987: Tottori University, Faculty of Agriculture, 農学部, 助教授 1986: 鳥取大, 農学部, 助教授
Review Section/Research Field	Principal Investigator 蚕糸学 Except Principal Investigator 蚕糸・昆虫利用学 / 蚕糸学 / Science and Engineering / Chemistry
Keywords	Principal Investigator エステラーゼA_4 / 時計 / 時間をはかるタンパク質 / カイコ / 休眠 / 活性化 / 低温 / グアニジンーHCl / エステラーゼ【A_4】 / グアニジン-Hcl … More / Esterase A_4 / Clock / Time measuring protein / Silkworm / Diapause / Activation / Cold … More Except Principal Investigator V-ATPase / カイコ / 絹糸腺 / silk gland / キボシカミキリ / 分類 / 生態型 / 電気泳動 / 消化管 / アミノ酸輸送 / カリウムポンプ / プロトンポンプ / silkworm / midgut / amino acid transport / Potassium pump / Proton pump / Bombyx mori / 生理活性発現分子機構 / 全合成 / タンパク質分子修飾 / 相互作用 / 構造認識機構 / タンパク質脱リン酸酵素阻害剤 / 時間読みタンパク質 / テトロドトキシン / シガトキシン / 発光タンパク質 / タンパク質脱リン酸酵素阻害 / 分子間相互作用 / 光親和性標識 / タンパク脱リン酸酵素阻害 / 時間読みタンパク / エステラーゼ / ホスファターゼ / エステラ-ゼ / 地理的変異 / 系統分類 / 生態系 / Yellow-spotted longicorn beetle / Esterase isozymes / Electrophoresis / Geographic variation / Phylogenic systematics / pH調節 / 水チャネル / 液状絹タンパク質 / 能動輸送 / 水チャンネル / water channel / liquid silk / active transport / silkworm, Bombyx mori Less

The Innovative Synthesis of Bioactive Molecules based on the Molecular Mechanism of Natural Products Activity
- Principal Investigator
  
  ISOBE Minoru
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  Nagoya University
pH and water regulation in the silk gland of Bombyx mori in relation to gel-sol transition of the liquid silk in the glandular lumen
- Principal Investigator
  
  AZUMA Masaaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  蚕糸・昆虫利用学
- Research Institution
  Tottori University
Molecular physiology on H^+-translocating vacuolar-type ATPase in silkworms
- Principal Investigator
  
  AZUMA Masaaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  蚕糸・昆虫利用学
- Research Institution
  Tottori University
Molecular physiology on ion transport sytems in silkworms
- Principal Investigator
  
  AZUMA Masaaki
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  蚕糸・昆虫利用学
- Research Institution
  Tottori University
Geographic variation of esterase zymogram on the yellow-spotted longicorn beetle
- Principal Investigator
  
  KOBARA Ryuzo
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  蚕糸学
- Research Institution
  Tottori University
キボシカミキリの種分類学的研究
- Principal Investigator
  
  KOBARA Ryuzo
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  蚕糸学
- Research Institution
  Tottori University
Molecular mechanism of biological time keeping from the viewpoint of structural change in esterase A_4 emzyme proteinPrincipal Investigator
- Principal Investigator
  
  KAI Hidenori
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  蚕糸学
- Research Institution
  Tottori University

All 2009 2008 2007 2006 2004 Other

All Journal Article

[Journal Article] Molecular Heterogeneity of TIME-EA 4, a Timer Protein in Silkworm Diapause Eggs. Suthasinee Pitchayawasin-Thapphasaraphong2009
- Author(s)
  Tani N., Isobe, M., Kai, H., Kurahashi, T., Kato,J., Trisunan. S.
- Journal Title
  
  Biochem. Biosciences and Biotechnology (Accepted for publication)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Interactions between TIME and PIN could play a role in the system that controls the duration of diapause development and synchronization with seasonal cycles in the silkworm Bombyx mori2008
- Author(s)
  Kai, H.; Tani, N.; Isobe, M.
- Journal Title
  
  Entomol. Res. 38
  
  Pages: 179-187
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Protein Phosphatase Inhibitory Activity of Tautomycin Photoaffinity Probes Evaluated at Femto-molar Level2008
- Author(s)
  Magne O. Sydnes, Masaki Kuse, Masakuni Kurono, Aya Shimomura, Hiroshi Ohinata, Akira Takai and Minoru Isobe
- Journal Title
  
  Bioorg. Med. Chem. 16
  
  Pages: 1747-1755
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Protein Phosphatase Inhibitory Activity of Tautomycin Photoaffinity Probes Evaluated at Femto-molar Level2008
- Author(s)
  Sydnes, M.O., Kuse,M., Kurono, M., Shimomura, A., Ohinata, H., Takai. A Isobe, M.
- Journal Title
  
  Bioorg. Med. Chem. 16
  
  Pages: 1747-1755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Protein Phosphatase Inhibitory Activity of Tautomycin Photoaffinity Probes Evaluated at Femto-molar Level.2007
- Author(s)
  Sydnes, M. O.; Kuse, M.; Kurono, M.; Shimomura, A.; Ohinata, H.; Takai, A.; Isobe, M.
- Journal Title
  
  Bioorg. Med. Chem. 16
  
  Pages: 1747-1755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Synthesis of [18,19,21,22-13C4]-Labeled Tautomycin as an NMR probe of protein phosphatase inhibitor2007
- Author(s)
  Isobe, M.; Kurono, M.; Tsuboi, K.; Takai, A.
- Journal Title
  
  Chem. Asia J. 2
  
  Pages: 377-385
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Synthesis of [18,19,21,22-13C4]-labeled tautomycin as NMR probe of protein phosphatase inhibitor.2007
- Author(s)
  Isobe, M., Kurono, M., Tsuboi, K., Takai, A.
- Journal Title
  
  Chemistry-An Asia Journal
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] The Molecular Mechanism of the Termination of Insect Diapause, Part 1: A Timer Protein, TIME-EA4, in the Diapause Eggs of the Silkworm Bombyx mori is a Metallo-Glycoprotein2006
- Author(s)
  Isobe, M.; Kai, H.; Kurahashi, T.; Suwan, S.; Pitchayawasin-T. S.; Franz, T.; Tani, N.; Higashi, K.; Nishida, H.
- Journal Title
  
  Chem Bio Chem. 7
  
  Pages: 1590-1598
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Time-measurement-regulating peptide PIN may alter a timer conformation of Time Interval Measuring Enzyme (TIME).2006
- Author(s)
  Ti, Xiaonan, Tani N., Isobe, M., Kai, H.
- Journal Title
  
  J. Insect Physiology 52
  
  Pages: 461-467
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] A Molecular Mechanism of the Termination of Insect Diapause-a Timer Protein, TIME-EA4 in the Diapause Eggs of the Silkworm, Bombyx mori.2006
- Author(s)
  Isobe, M., Kai, H., Kurahashi, T., Suwan.S., Pitchayawasin-T.S., Franz, T., Tani, N., Higashi, K., Nishida, H.
- Journal Title
  
  ChemBioChem. 7
  
  Pages: 1590-1598
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Time-measurement-regulating peptide PIN may alter a timer conformation of Time Interval Measuring Enzyme (TIME)2006
- Author(s)
  Ti, Xiaonan; Tani N.; Isobe, M.; Kai, H.
- Journal Title
  
  J. Insect Physiology 52
  
  Pages: 461-467
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Demarcation of diapause development by cold and its relation to time-interval activation of TIME-ATPase in eggs of the silkworm, Bombyx mori2004
- Author(s)
  Ti, X.; Tuzuki, N.; Tani, N.; Morigami, E.; Isobe, M.; Kai, H.
- Journal Title
  
  J. Insect Physiol. 50
  
  Pages: 1053-1064
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Stereoselective Synthesis of the Fully Functionalized HIJ-ring Framework of Ciguatoxin2004
- Author(s)
  Baba, T.; Takai, S.; Sawada, N.; Isobe, M.
- Journal Title
  
  Synlett
  
  Pages: 603-608
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Stereoselective synthesis of the fully functionalized HIJ-ring framework of ciguatoxin2004
- Author(s)
  Baba, T., Takai, S., Sawada, N., Isobe, M.
- Journal Title
  
  Synlett
  
  Pages: 603-608
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Structure of pentasaccharide of glycopeptide from TIME-EA4, N-glycoprotein in Silkworm Diapause Eggs2004
- Author(s)
  Pitchayawasin, S.; Isobe, M.; Tani, N.; Kai, H.
- Journal Title
  
  Bioorg. Med. Chem. Lett. 14
  
  Pages: 2527-2531
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Structure of Pentasaccharide of Glycopeptide from TIME-EA4, N-Glycoprotein in Silkworm Diapause Eggs.2004
- Author(s)
  Pitchayawasin, S., Isobe, M., Tani, N., Kai, H.
- Journal Title
  
  Bioorganic & Medicinal Chem. Lett 14
  
  Pages: 2527-2531
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] インターバルタイマータンパク質TIME、ねじまきPIN付き2004
- Author(s)
  甲斐英則・谷直樹・磯部稔
- Journal Title
  
  時間生物学 10(#1)
  
  Pages: 28-34
- NAID
  10013423160
- Data Source
  KAKENHI-PROJECT-16002007
[Journal Article] Molecular Heterogeneity of TIME-EA4, a Timer Protein in Silkworm Diapause Eggs. Suthasinee Pitchayawasin-Thapphasaraphong
- Author(s)
  Naoki Tani, Minoru Isobe, Hidenori Kai, Takuya Kurahashi, Junko Kato, Saikwan Trisunan
- Journal Title
  
  Biochem. Biosciences and Biotechnology (in press)
- Data Source
  KAKENHI-PROJECT-16002007

1. KOBARA Ryuzo (70032092)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. AZUMA Masaaki (20175871)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. ISOBE Minoru (00023466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
4. ICHIKAWA Yoshiyasu (60193439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NISHIKAWA Toshio (90208158)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KUSE Masaki (40335013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. ADACHI Masaatsu (80432251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KOBAYASHI Masahiko (60162020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SASAKI Sadao (20104276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MORI Hajime (80201812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MAEDA Susumu (30116371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KAWAI Jakashi (80032043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAI Hidenori 甲斐 英則

Research Projects

Research Products

Co-Researchers

The Innovative Synthesis of Bioactive Molecules based on the Molecular Mechanism of Natural Products Activity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

pH and water regulation in the silk gland of Bombyx mori in relation to gel-sol transition of the liquid silk in the glandular lumen

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular physiology on H^+-translocating vacuolar-type ATPase in silkworms

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular physiology on ion transport sytems in silkworms

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Geographic variation of esterase zymogram on the yellow-spotted longicorn beetle

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

キボシカミキリの種分類学的研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of biological time keeping from the viewpoint of structural change in esterase A_4 emzyme proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Molecular Heterogeneity of TIME-EA 4, a Timer Protein in Silkworm Diapause Eggs. Suthasinee Pitchayawasin-Thapphasaraphong2009

Author(s)

Journal Title

Data Source

[Journal Article] Interactions between TIME and PIN could play a role in the system that controls the duration of diapause development and synchronization with seasonal cycles in the silkworm Bombyx mori2008

Author(s)

Journal Title

Data Source

[Journal Article] Protein Phosphatase Inhibitory Activity of Tautomycin Photoaffinity Probes Evaluated at Femto-molar Level2008

Author(s)

Journal Title

Data Source

[Journal Article] Protein Phosphatase Inhibitory Activity of Tautomycin Photoaffinity Probes Evaluated at Femto-molar Level2008

Author(s)

Journal Title

Data Source

[Journal Article] Protein Phosphatase Inhibitory Activity of Tautomycin Photoaffinity Probes Evaluated at Femto-molar Level.2007

Author(s)

Journal Title

Data Source

[Journal Article] Synthesis of [18,19,21,22-13C4]-Labeled Tautomycin as an NMR probe of protein phosphatase inhibitor2007

Author(s)

Journal Title

Data Source

[Journal Article] Synthesis of [18,19,21,22-13C4]-labeled tautomycin as NMR probe of protein phosphatase inhibitor.2007

Author(s)

Journal Title

Data Source

[Journal Article] The Molecular Mechanism of the Termination of Insect Diapause, Part 1: A Timer Protein, TIME-EA4, in the Diapause Eggs of the Silkworm Bombyx mori is a Metallo-Glycoprotein2006

Author(s)

Journal Title

Data Source

[Journal Article] Time-measurement-regulating peptide PIN may alter a timer conformation of Time Interval Measuring Enzyme (TIME).2006

Author(s)

KAI Hidenori 甲斐英則