HIRAI Keiichi 平井圭一

… Alternative Names

HIRAI Kei-Ichi 平井圭一

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Researcher Number	60027092
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2002 – 2006: 金沢医科大学, 医学部, 教授 1994 – 1997: 金沢医科大学, 医学部, 教授 1987 – 1990: Dept. of Anatomy, Kanazawa Med Univ., 医学部, 教授 1986: 金沢医大, 医学部, 教授
Review Section/Research Field	Principal Investigator General anatomy (including Histology/Embryology) / Anesthesiology/Resuscitation studies Except Principal Investigator Emergency medicine / Orthopaedic surgery
Keywords	Principal Investigator パラコート / コラーゲン / 人工気管 / チトクロムP-450 / ブロムベンゼン / herbicide / superoxide / mitochondria / paraquat / ミトコンドリア … More / 肺障害 / Collagen / Eosinophil / Bronchial asthma / Peroxidase / Mycoplasma / Tracheal graft / Bronchiole / Trachea / 高分子材料 / 細胞外基質 / 気管上皮の分化 / 呼吸上皮の再生 / 細胞分化 / 上皮再生 / 気管支上皮 / 線毛細胞 / 細気管支上皮 / 気管上皮 / コラ-ゲン / 好酸球 / 気管支喘息 / ペルオキシダ-ゼ / マイコプラズマ / 人工気管補填材 / 細気管支 / 気管 / cytochtome P-450 / Clara cell / mitochodrial injury / bronchiole / brombenzene / pataquat / ペルオキシダーゼ / 活性酸素産生 / チトクロームオキシダーゼ / 呼吸上皮再生 / クララ細胞 / ミトコンドリア傷害 / 気管支 / permeability transition pore / voltage-dependent anion channel / NADH-quinone oxidoreductase / 電位依存性アニオンチャンネル / 電位依存性アニオンチャネル / ミクロソーム / チトクロムP450 / 解毒作用 / 急性毒性 / 除草剤 / rotenone-insensitive NADH oxidation / free radicals / lung injury / 農薬中毒 / ロテノン非感受性NADHオキシダーゼ / パラコート中毒 / 農薬 / ロテノン非感受性NADH酸化 / スーパーオキシド / フリーラジカル / ミトコンドリア障害 … More Except Principal Investigator voltage-dependent anion channel / NADH / hydrogen peroxide / superoxide / NADH-quinone oxidoreductasem / cytotoxicity / mitochondria / paraquat / permeability transition pore / NADH-quinone oxidoreductase_m / 外膜チャネル / 活性酸素 / フリーラジカル生成 / voltage-dependeit anion diannel / 細胞毒性 / ミトコンドリア / パラコート / neurotrophic factor / collagen / fibronectin / laminin / nerve regeneration / nerve graft / homotransplantation / allotransplantation / 神経移植 / 末梢神経 / 神経成長因子 / コラーゲン / フィブロネクチン / ラミニン / 神経再生 / 人工神経 / 神経同種移植 / 神経異種移植 Less

Mitochondrial voltage-dependent anion channel is responsible for paraquat cytotoxicity.
- Principal Investigator
  
  SHIMADA Hiroki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  KANAZAWA MEDICAL UNIVERSITY
Acute Cytotoxic Mechanisms and Detoxic Mechanisms of Paraquat PoisoningPrincipal Investigator
- Principal Investigator
  
  HIRAI Keiichi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kanazawa Medical University
Basic Research of Peripheral Nerve Regeneration and Grafts for Transplantation
- Principal Investigator
  
  TODA Norihiko
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kanazawa Medical University
Mitochondrial Injury as the Mechanism of Paraquat ToxicityPrincipal Investigator
- Principal Investigator
  
  HIRAI Keiichi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kanazawa Medical University
Regeneration Mechanisms and Differentiation of Tracheoblonchiolar EpitheliaPrincipal Investigator
- Principal Investigator
  
  HIRAI Kei-ichi
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kanazawa Medical University
Electron Microscopic Study on the Lung Cell Injuries Produced by Environmenta ChemicalsPrincipal Investigator
- Principal Investigator
  
  HIRAI Kei-Ichi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kanazawa Medical University

All 2005 2004 2003 2002

All Journal Article

[Journal Article] 紅豆杉天然成分による癌細胞増殖抑制とApoptosis誘導2005
- Author(s)
  平井圭一, 島田ひろき, 島村英理子, 他
- Journal Title
  
  第3回補完医薬学会抄録集
  
  Pages: 7-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] ミトコンドリア膜透過性タンパクによるフラノナフトキノン誘導体の活性酸素生成2004
- Author(s)
  島村英理子, 平井圭一, 島田ひろき, 他
- Journal Title
  
  ミトコンドリア研究会年会要旨集
  
  Pages: 26-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] ミトロンドリア膜透過性タンパクによるフラノナフトキノン誘導体の活性酸素生成2004
- Author(s)
  島村英理子, 平井圭一, 島田ひろき, 他
- Journal Title
  
  ミトロンドリア研究会年会要旨集
  
  Pages: 26-26
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] The participation of mitochondrial membrane permeable protein in mitochondrial damage by an anticancer agent furanonaphthoquinone2004
- Author(s)
  E.Simamura, H.Shimada, K.-I.Hirai, et al.
- Journal Title
  
  8th Asia-Pacific Conference on Electron Microscopy, 2004 PROC.
  
  Pages: 1325-1326
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] Defense of UV-induced cell death by antioxidants2004
- Author(s)
  K.Furuta, K.-I.Hirai, H.Shimada, et al.
- Journal Title
  
  8th Asia-Pacific Conference on Electron Microscopy, 2004 PROC.
  
  Pages: 1179-1180
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] The participation of voltage dependent anion channel (VDAC) protein in NADH-quinone oxidoreductasem activity on paraquat cytotoxicity2004
- Author(s)
  H.Shimada, K.-I.Hirai, E.Simamura, et al.
- Journal Title
  
  8th Asia-Pacific Conference on Electron Microscopy, 2004 PROC.
  
  Pages: 1229-1230
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] ミトコンドリアを標的とする抗腫瘍物質フラノナフトキノン誘導体の研究2003
- Author(s)
  島村英理子, 平井圭一, 島田ひろき, 他
- Journal Title
  
  ミトコンドリア研究会年会要旨集
  
  Pages: 29-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] Mitochondrial damage prior to apoptosis in furanonaphthoquinone treated lung cancer cells2003
- Author(s)
  E.Simamura, K.-I.Hirai, H.Shimada, et al.
- Journal Title
  
  Cancer Detect.Prev. 27
  
  Pages: 5-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] パラコートのミトコンドリア障害に対するミトコンドリア膜透過性蛋白の関与2003
- Author(s)
  島村英理子, 島田ひろき, 平井圭一, 他
- Journal Title
  
  電子顕微鏡(目本顕微鏡学会第59回学術講演会プロシーディングス) 38(補1)
  
  Pages: 199-199
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] パラコートのミトコンドリア毒性に関与する膜透過性タンパク質の蛍光画像解析2003
- Author(s)
  島田ひろき, 平井圭一, 島村英理子, 他
- Journal Title
  
  電子顕微鏡(日本顕微鏡学会第59回学術講演会プロシーディングス) 38(補1)
  
  Pages: 200-200
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] パラコート細胞毒性に関与するNADH-quinone oxidoreductasem活性の探求2003
- Author(s)
  島田ひろき, 平井圭一, 島村英理子, 他
- Journal Title
  
  ミトコンドリア研究会年会要旨集
  
  Pages: 60-60
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] The use of EF-TEM for visualizing free radical production in human leukocytes engaged in phagocytosis2002
- Author(s)
  K.Moriguchi, K.-I.Hirai, T.Kurihara, et al.
- Journal Title
  
  ICEM-15 DURBAN 2002 2
  
  Pages: 525-526
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] EF-TEM findings of new anticancer agents to procuce suicidal free radicals in mitochondria2002
- Author(s)
  K.-I.Hirai, E.Simamura, H.Shimada, et al.
- Journal Title
  
  ICEM-15 DURBAN 2002 2
  
  Pages: 537-538
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] Alpha-tochopherol protects cultured human cells from the acute lethal cytotoxicity of dioxin2002
- Author(s)
  K.-I.Hirai, H.Simamura, H.Shimada, et al.
- Journal Title
  
  Int.J.Vitam Nutr Res 72
  
  Pages: 147-153
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474
[Journal Article] Paraquat detoxicative system in the mouse liver postmitochondrial fraction2002
- Author(s)
  H.Shimada, H.Furuno, K.-I.Hirai, E.Simamura, et al.
- Journal Title
  
  Arch Biochem Biophys 402
  
  Pages: 149-157
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571474

1. SIMADA Hiroki (60278108)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
2. MORIGUCHI Keiichi (30139779)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. SIMAMURA Eriko (00267741)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. UEDA Tadashi (80151794)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. AONO Makoto (10014218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TODA Norihiko (60131025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YUASA Yasuhiro (90288291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MASUTANI Atsushi (80288290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KOYAMA Junko (60102109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 水谷善弘 (10257470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HIRAI Keiichi 平井 圭一

HIRAI Kei-Ichi 平井 圭一

Research Projects

Research Products

Co-Researchers

Mitochondrial voltage-dependent anion channel is responsible for paraquat cytotoxicity.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Acute Cytotoxic Mechanisms and Detoxic Mechanisms of Paraquat PoisoningPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic Research of Peripheral Nerve Regeneration and Grafts for Transplantation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mitochondrial Injury as the Mechanism of Paraquat ToxicityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regeneration Mechanisms and Differentiation of Tracheoblonchiolar EpitheliaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Electron Microscopic Study on the Lung Cell Injuries Produced by Environmenta ChemicalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 紅豆杉天然成分による癌細胞増殖抑制とApoptosis誘導2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] ミトコンドリア膜透過性タンパクによるフラノナフトキノン誘導体の活性酸素生成2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] ミトロンドリア膜透過性タンパクによるフラノナフトキノン誘導体の活性酸素生成2004

Author(s)

Journal Title

Data Source

[Journal Article] The participation of mitochondrial membrane permeable protein in mitochondrial damage by an anticancer agent furanonaphthoquinone2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Defense of UV-induced cell death by antioxidants2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] The participation of voltage dependent anion channel (VDAC) protein in NADH-quinone oxidoreductasem activity on paraquat cytotoxicity2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] ミトコンドリアを標的とする抗腫瘍物質フラノナフトキノン誘導体の研究2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Mitochondrial damage prior to apoptosis in furanonaphthoquinone treated lung cancer cells2003

Author(s)

Journal Title

Description

Data Source

HIRAI Keiichi 平井圭一

HIRAI Kei-Ichi 平井圭一