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OHMOTO Takashi  大本 堯史

ORCIDConnect your ORCID iD *help
… Alternative Names

大本 堯史  オオモト タカシ

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Researcher Number 60032900
External Links
Affiliation (based on the past Project Information) *help 2001 – 2002: 岡山大学, 大学院・医歯学総合研究科, 教授
1992 – 2000: 岡山大学, 医学部, 教授
1989 – 1990: 香川医科大学, 医学部, 教授
1986: 香川医科大学, 医学部, 教授
Review Section/Research Field
Principal Investigator
Cerebral neurosurgery
Except Principal Investigator
Cerebral neurosurgery
Keywords
Principal Investigator
パーキンソン病 / Parkinson's disease / 神経栄養因子 / 遺伝子導入 / DNA / 遺伝子治療 / GDNF / ドパミン / 遺伝子 / gene … More / クモ膜下出血 / 脳血管攣縮 / 透過性変化 / 血液ー血管壁関門 / トレ-サ-研究 / 血管内皮細胞 / 脳血管壁透過性 / トレ-サ-スタディ / ロイコトリエン / Subarachnoid Hemorrhage / Cerebral Vasospasm / Changes in Permeability / Bood Arterial Wall Barrier / Trancer Study / Endothelial Injury / 神経移植 / β-galactosidase / gene transfer / neural transplantation / beta galactosidase / カプセル化細胞 / ドーパミン / gene therapy / encapsulated cells / CDNF / dopamine / 神経伝達物質 / neurotransmitter / neurotrophic factor … More
Except Principal Investigator
神経栄養因子 / GDNF / パーキンソン病 / 神経移植 / カプセル化細胞 / neurotrophic factor / Parkinson's disease / neural transplantation / pp60^<src> / 遺伝子治療 / 脳梗塞 / アデノウイルス / くも膜下出血 / 増殖型血管症 / 血小板由来増殖因子 / 脳血管攣縮 / クモ膜下出血 / 血小板 / 抗血小板剤 / 血小板由来成長因子 / Subarachnoid hemorrhage / Proliferative angiopathy / Platelet-derived angiopathy / Cerebral vasospasm / 外傷性てんかん / 鉄イオン誘導てんかん焦点 / スーパーオキシド / ヒドロキシルラジカル / 一酸化窒素 / スーパーオキシドジムスターゼ / α-グアニジノグルタル酸 / アデノシン / スパーオキシド / 遷移金属 / エピガロカエキン / ドーパミンニューロン / 酸化窒素ラジカル / 硝酸イオン / 亜硝酸イオン / 活性酸素種 / フローインジェクション法 / セカンドメッセンジャー / 血管拡張因子 / posttraumatic epilepsy / iron-iduced epileptogenic focus / superoxide / hydroxyl radical / nitric oxide / superoxide dismutase / alpha-guanidinoglutaric acid / adnosine / encapsulated cell / 蛋白質セラピー法 / Invivo Protein Transduction / カルシニューリン / カルパイン / カルバスタチン / アポトーシス / 神経細胞死 / カルシウムチャネル / 免疫抑制剤 / FK506結合蛋白質 / シクロスポリン / 膀胱肥大 / FK506 / 蛋白質セラピー / In vivo Protein Transduction / TAT / Aキナーゼ / 長期増強 / PKI / Calcineurin / Calpain / Calpastatin / Neuronal cell death / Apoptosis / Glutamate / Protein therapy / 細胞移植 / 神経伝達物質 / ドパミン / neurotransmitter / 脳腫瘍 / グリオーマ / がん遺伝子 / がん遺伝子産物 / flow cytometer / 上皮成長因子受容体 / p21^<ras> / グリオーマ細胞 / pp【60^(src)】 / 脱分化 / flow cytometry / Brain tumor / Oncogenes / Oncogene-products / Flow cytometer / Epidermal growth factor receptor(EGF-R) Less
  • Research Projects

    (12 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (32 People)
  •  Gene induction of neurotranmitters and neurotrophic factors for the treatment of Parkinson's diseasePrincipal Investigator

    • Principal Investigator
      ONO Shigeki, 大本 尭史 (大本 堯史)
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Encapsulated neurotransmitter and neurotrophic factor secreting cell grafting for the treatment of Parkinson's disease

    • Principal Investigator
      DATE Isao
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  神経栄養因子蛋白および遺伝子治療による脳梗塞治療の萌芽的基礎研究

    • Principal Investigator
      阿部 康二
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Okayama University
  •  Role of Calpain-mediated Cleavage of Calcineurin in Excitotoxic Neurodegeneration

    • Principal Investigator
      MATSUI Hideki
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  NEUROTROPHIC FACTOR GENE TRANSFER INTO THE BRAIN FOR THE TREATMENT OF PARKINSON'S DISEASEPrincipal Investigator

    • Principal Investigator
      OHMOTO Takashi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  ENCAPSULATED TROPHIC FACTOR SECRETING CELL GRAFTING FOR THE TREATMENT OF PARKINSON'S DISEASE

    • Principal Investigator
      DATE Isao
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Gene therapy for Parkinson's diseasePrincipal Investigator

    • Principal Investigator
      OHMOTO Takashi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Okayama University
  •  INTRACEREBRAL GRAFTING OF ENGINEERED CELLSPrincipal Investigator

    • Principal Investigator
      OHMOTO Takashi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Reactive oxygen species are involved in the mechanism of epileptogenic focus formation after head injury.

    • Principal Investigator
      MORI Akitane
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Okayama University Medical School
  •  クモ膜下出血後の増殖型血管症におよぼす血小板の役割について

    • Principal Investigator
      HONMA Yutaka
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kagawa Medical School
  •  Experimental Study of the Mechanism of Cerebral VasospasmPrincipal Investigator

    • Principal Investigator
      OHMOTO Takashi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kagawa Medical School
  •  Qualitative and quantitative study of oncogene-products in gliomas.

    • Principal Investigator
      TABUCHI Kazuo
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Saga Medical School
      香川医科大学

All 2002 2001

All Journal Article

  • [Journal Article] 脳内細胞移植療法:臨床的立場から2002

    • Author(s)
      伊達 勲, 新郷哲郎, 大本堯史
    • Journal Title

      神経進歩 46

      Pages: 285-296

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13671436
  • [Journal Article] Parkinson病の治療:細胞移植術の現状と展望2001

    • Author(s)
      大本堯史, 伊達 勲
    • Journal Title

      Clin Neurosci 19

      Pages: 704-705

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13470294
  • 1.  DATE Isao (70236785)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 2 results
  • 2.  FURUTA Tomohisa (30181457)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  TOMITA Susumu (90237115)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  ONO Shigeki (40335625)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  HONMA Yutaka (60209343)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  ASARI Shoji (40175857)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  ONO Yasuhiro (40294409)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SUGIU Kenji (40325105)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  TOKUNAGA Kouji (40294467)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  MIYOSHI Yasuyuki (00362997)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  MATSUI Toshihiro (80362995)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  西尾 晋作 (80325109)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  MORI Akitane (20028434)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TSUTSUI Kimiko (70144748)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MIZUKAWA Kiminao (40137154)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YOKOI Isao (80150366)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MATSUI Hideki (30157234)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  LI Sheng-tiara (90325093)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  TOMIZAWA Kazuhito (40274287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  MATSUSHITA Masayuki (30273965)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  MORIWAKI Akiyoshi (10144742)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  TABUCHI Kazuo (50116480)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  EGAMI Hiroto (30176755)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  阿部 康二 (20212540)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  松原 悦朗 (70219468)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  佐藤 圭子 (20325103)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  大森 信彦 (80311421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  林 健 (40314679)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  三野 章呉 (40174106)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  吉岡 純二 (40166913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  植田 清隆 (50144738)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  本田 千穂
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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