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OHMOTO Takashi  大本 堯史

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… Alternative Names

大本 堯史  オオモト タカシ

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Researcher Number 60032900
External Links
Affiliation (based on the past Project Information) *help 2001 – 2002: 岡山大学, 大学院・医歯学総合研究科, 教授
1992 – 2000: 岡山大学, 医学部, 教授
1989 – 1990: 香川医科大学, 医学部, 教授
1986: 香川医科大学, 医学部, 教授
Review Section/Research Field
Principal Investigator
Cerebral neurosurgery
Except Principal Investigator
Cerebral neurosurgery
Keywords
Principal Investigator
Parkinson's disease / パーキンソン病 / 神経栄養因子 / gene / 遺伝子 / ドパミン / GDNF / 遺伝子治療 / DNA / 遺伝子導入 … More / neurotrophic factor / neurotransmitter / 神経伝達物質 / dopamine / CDNF / encapsulated cells / gene therapy / ドーパミン / カプセル化細胞 / beta galactosidase / neural transplantation / gene transfer / β-galactosidase / 神経移植 / Endothelial Injury / Trancer Study / Bood Arterial Wall Barrier / Changes in Permeability / Cerebral Vasospasm / Subarachnoid Hemorrhage / ロイコトリエン / トレ-サ-スタディ / 脳血管壁透過性 / 血管内皮細胞 / トレ-サ-研究 / 血液ー血管壁関門 / 透過性変化 / 脳血管攣縮 / クモ膜下出血 … More
Except Principal Investigator
神経栄養因子 / pp60^<src> / neural transplantation / Parkinson's disease / neurotrophic factor / カプセル化細胞 / 神経移植 / パーキンソン病 / GDNF / Epidermal growth factor receptor(EGF-R) / Flow cytometer / Oncogene-products / Oncogenes / Brain tumor / flow cytometry / 脱分化 / pp【60^(src)】 / グリオーマ細胞 / p21^<ras> / 上皮成長因子受容体 / flow cytometer / がん遺伝子産物 / がん遺伝子 / グリオーマ / 脳腫瘍 / neurotransmitter / ドパミン / 神経伝達物質 / 細胞移植 / Protein therapy / Glutamate / Apoptosis / Neuronal cell death / Calpastatin / Calpain / Calcineurin / PKI / 長期増強 / Aキナーゼ / TAT / In vivo Protein Transduction / 蛋白質セラピー / FK506 / 膀胱肥大 / シクロスポリン / FK506結合蛋白質 / 免疫抑制剤 / カルシウムチャネル / 神経細胞死 / アポトーシス / カルバスタチン / カルパイン / カルシニューリン / Invivo Protein Transduction / 蛋白質セラピー法 / encapsulated cell / adnosine / alpha-guanidinoglutaric acid / superoxide dismutase / nitric oxide / hydroxyl radical / superoxide / iron-iduced epileptogenic focus / posttraumatic epilepsy / 血管拡張因子 / セカンドメッセンジャー / フローインジェクション法 / 活性酸素種 / 亜硝酸イオン / 硝酸イオン / 酸化窒素ラジカル / ドーパミンニューロン / エピガロカエキン / 遷移金属 / スパーオキシド / アデノシン / α-グアニジノグルタル酸 / スーパーオキシドジムスターゼ / 一酸化窒素 / ヒドロキシルラジカル / スーパーオキシド / 鉄イオン誘導てんかん焦点 / 外傷性てんかん / Cerebral vasospasm / Platelet-derived angiopathy / Proliferative angiopathy / Subarachnoid hemorrhage / 血小板由来成長因子 / 抗血小板剤 / 血小板 / クモ膜下出血 / 脳血管攣縮 / 血小板由来増殖因子 / 増殖型血管症 / くも膜下出血 / アデノウイルス / 脳梗塞 / 遺伝子治療 Less
  • Research Projects

    (12 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (32 People)
  •  Gene induction of neurotranmitters and neurotrophic factors for the treatment of Parkinson's diseasePrincipal Investigator

    • Principal Investigator
      ONO Shigeki, 大本 尭史 (大本 堯史)
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Encapsulated neurotransmitter and neurotrophic factor secreting cell grafting for the treatment of Parkinson's disease

    • Principal Investigator
      DATE Isao
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  神経栄養因子蛋白および遺伝子治療による脳梗塞治療の萌芽的基礎研究

    • Principal Investigator
      阿部 康二
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Okayama University
  •  Role of Calpain-mediated Cleavage of Calcineurin in Excitotoxic Neurodegeneration

    • Principal Investigator
      MATSUI Hideki
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  NEUROTROPHIC FACTOR GENE TRANSFER INTO THE BRAIN FOR THE TREATMENT OF PARKINSON'S DISEASEPrincipal Investigator

    • Principal Investigator
      OHMOTO Takashi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  ENCAPSULATED TROPHIC FACTOR SECRETING CELL GRAFTING FOR THE TREATMENT OF PARKINSON'S DISEASE

    • Principal Investigator
      DATE Isao
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Gene therapy for Parkinson's diseasePrincipal Investigator

    • Principal Investigator
      OHMOTO Takashi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Okayama University
  •  INTRACEREBRAL GRAFTING OF ENGINEERED CELLSPrincipal Investigator

    • Principal Investigator
      OHMOTO Takashi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Reactive oxygen species are involved in the mechanism of epileptogenic focus formation after head injury.

    • Principal Investigator
      MORI Akitane
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Okayama University Medical School
  •  クモ膜下出血後の増殖型血管症におよぼす血小板の役割について

    • Principal Investigator
      HONMA Yutaka
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kagawa Medical School
  •  Experimental Study of the Mechanism of Cerebral VasospasmPrincipal Investigator

    • Principal Investigator
      OHMOTO Takashi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kagawa Medical School
  •  Qualitative and quantitative study of oncogene-products in gliomas.

    • Principal Investigator
      TABUCHI Kazuo
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Saga Medical School
      香川医科大学

All 2002 2001

All Journal Article

  • [Journal Article] 脳内細胞移植療法:臨床的立場から2002

    • Author(s)
      伊達 勲, 新郷哲郎, 大本堯史
    • Journal Title

      神経進歩 46

      Pages: 285-296

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13671436
  • [Journal Article] Parkinson病の治療:細胞移植術の現状と展望2001

    • Author(s)
      大本堯史, 伊達 勲
    • Journal Title

      Clin Neurosci 19

      Pages: 704-705

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13470294
  • 1.  DATE Isao (70236785)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 2 results
  • 2.  FURUTA Tomohisa (30181457)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  TOMITA Susumu (90237115)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  ONO Shigeki (40335625)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  HONMA Yutaka (60209343)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  ASARI Shoji (40175857)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  ONO Yasuhiro (40294409)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SUGIU Kenji (40325105)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  TOKUNAGA Kouji (40294467)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  MIYOSHI Yasuyuki (00362997)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  MATSUI Toshihiro (80362995)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  西尾 晋作 (80325109)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  MORI Akitane (20028434)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TSUTSUI Kimiko (70144748)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MIZUKAWA Kiminao (40137154)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YOKOI Isao (80150366)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  MATSUI Hideki (30157234)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  LI Sheng-tiara (90325093)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  TOMIZAWA Kazuhito (40274287)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  MATSUSHITA Masayuki (30273965)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  MORIWAKI Akiyoshi (10144742)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  TABUCHI Kazuo (50116480)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  EGAMI Hiroto (30176755)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  阿部 康二 (20212540)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  松原 悦朗 (70219468)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  佐藤 圭子 (20325103)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  大森 信彦 (80311421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  林 健 (40314679)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  三野 章呉 (40174106)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  吉岡 純二 (40166913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  植田 清隆 (50144738)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  本田 千穂
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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