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MAKINO Yoshihiro  牧野 芳大

ORCIDConnect your ORCID iD *help
Researcher Number 60039930
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2003 – 2010: Oita University, Department of Infectious Diseases, Professor, 医学部, 教授
2002: 大分医科大学, 医学部, 教授
1998: Univ.of Ryukyus, School of Med., Associate Prof., 医学部, 助教授
1988 – 1996: 琉球大学, 医学部, 助教授
Review Section/Research Field
Principal Investigator
Hygiene / Virology
Except Principal Investigator
Cerebral neurosurgery / Hygiene / 内科学一般 / Human pathology / Applied veterinary science / Virology
Keywords
Principal Investigator
分子系統樹 / 日本脳炎ウイルス / dengue envelope gene / dengue core gene / Baculovirus / Gene expression / Dengue 4 virus / 核内抗原 / コア遺伝子 / デングウイルス … More / デングE遺伝子 / デングコア遺伝子 / バキュロウイルス / 遺伝子発現 / デング4型ウイルス / Neutralization test / Phylogenetic tree / Genotype / Japanese encephalitis virus / 遺伝型の交代現象 / 遺伝子抗体現象 / 遺伝子系統樹 / 日本脳炎ウィルス / 中和試験 / 遺伝子型 / エンベロープ遺伝子 / 大分分離株 … More
Except Principal Investigator
gene therapy / glioblastoma / tumor vaccine / glioma / costimulatory signal / B7 / Glioblastoma / Gene therapy / RT-PCR / 感染症 / ヘリコバクタ・ピロリ感染 / ガストリン / ペプシノゲン / ドミニカ共和国 / 慢性萎縮性胃炎 / 胃がん / 分子疫学 / antibody therapy / Antibody engineering / humanized antibody / infectious diseases / tropical medicine / dengue infection / phage display / combinatorial science / 分子生物学 / 抗体療法 / デングウイルス / 抗体 / ファージディスプレイ / 抗体医療 / 抗体エンジニアリング / ヒト型抗体 / 熱帯医学 / デング / ファージディスプレイ法 / コンビナトリアル科学 / Tumor vaccine / 遺伝子治療 / 膠芽腫 / ワクチン療法 / 脳腫瘍 / Thymidine kinase / Proliferating pool / Ganciclovir / Gap-Junctional Intercellular Communication / Cell Cycle / Bystander effect / retro virus / Brau / Xthymidine kinase / gene xherapy / retrovirus / Flow cytometry / thymidine Rinase / DNA bistogram / flow cytometry / bystander effect / PCNA / cell cycle / HSV thymidine kinase / gene thcrapy / Tissue culture / Endothelial cell / Growth factor / kaposi's sarcoma / 免疫染色 / オンコスタチンM / 組織培養 / 古典型カポジー肉腫 / AIDSカポジー肉腫 / 増殖因子 / 血管内皮細胞 / カポジ-肉腫 / Serodiagnosis of strongyloidiasis / Strongyloidiasis / Heres simplex virus type 2 / Expressed protein by baculovirus system / Cross immune response in flavivirus infections / Dengue hemerrhgic fever / Japanese encephailtis / 診断用発現蛋白 / 単純ヘルペスウイルスII型(HSVーII) / デング出血熱(DHF) / 日本脳炎(JE) / 単純ヘルペスウイルスII型の病原性 / 単純ヘルペスウイルスII型 / 糞線虫症の血清学的診断法 / 糞線虫症の血清学的診断 / 糞線虫症 / 単純ヘルペスウイルスII / バキュロウイルスシステム発現蛋白 / フラビウイルスの免疫交叉応答 / デング出血熱 / 日本脳炎 / Cag A / 生活環境 / 生活習慣 / CagA / 小児 / 疫学 / CagA抗体 / ヘリコバクター・ピロリ(H.pylori)感染 / 昆虫 / ウイルス / プロテオーム / タンパク / 蚊 / ウエストナイルウイルス / 人獣共通感染症 / 民族疫学 / 中国 / タンザニア / ヘリコバクター・ピロリ(H. pylori)感染 / C-preM領域 / 沖縄株 / 日本脳炎ウイルス Less
  • Research Projects

    (12 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (33 People)
  •  Prevalence of H. pylori Infection and Chronic Atrophic Gastritis in the Dominican Children

    • Principal Investigator
      AOKI Kazuo
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      University of the Ryukyus
  •  Molecular evolution of Japanese encephalitis virus isolates circulating in Oita areas.Principal Investigator

    • Principal Investigator
      MAKINO Yoshihiro
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Oita University
  •  Epidemiological Study on the Effect of Helicobacter Pylori Infection on Chronic Atrophic Gastritis in Different Ethnic Groups

    • Principal Investigator
      AOKI Kazuo
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      University of the Ryukyus
      Oita University
  •  Analyses of the vector competence of Japanese mosquitoes to New York strain of West Nile virus

    • Principal Investigator
      ESHITA Yuki
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied veterinary science
    • Research Institution
      Oita University
  •  Shift of dominant genetic clusters of Japanese encephalitis virus in Kyushu areas.Principal Investigator

    • Principal Investigator
      MAKINO Yoshihiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Oita University
  •  Synthesis of human Fab

    • Principal Investigator
      YAMASHIRO Tetsu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      Oita University
  •  Vaccine therapy for malignant glioma with costimulatory signal genemodified syngenic glioma cells

    • Principal Investigator
      MIYAGI Koichi
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      UNIVERSITY OF THE RYUKYUS
  •  沖縄における日本脳炎ウイルスの分子疫学

    • Principal Investigator
      FUKUNAGA Toshihiko
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      University of the Ryukyus
  •  GENETHERAPY FOR MALIGNANTBRAIN TUMOR.-Improvement of transduction rate of recombinant retrovirus by modification of cell cycle, bystander effect-

    • Principal Investigator
      MIYAGI Koichi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      UNIVERSITY OF THE RYUKYUS
  •  Kaposi's sarcoma, proliferation and regression

    • Principal Investigator
      IWAMASA Teruo
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      University of the Rykyus
  •  Cooperative studies of seroepidemiology and pathogenesis of Viral and parasitie diseases in Okinawa and Thailand

    • Principal Investigator
      FUKUNAGA Toshihiko
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      University of the Ryukyus
  •  Research on the expression of dengue virus gene.Principal Investigator

    • Principal Investigator
      MAKINO Yoshihiro
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      University of the Ryukyus

All 2010 2008 2007 2004

All Journal Article Presentation Book

  • [Book] 環境報告書2008(2007年度)2008

    • Author(s)
      牧野芳大, 江下優樹
    • Total Pages
      41
    • Publisher
      地球温暖化の影響による亜熱帯地域の感染症拡大に関する疫学研究
    • Data Source
      KAKENHI-PROJECT-18580310
  • [Book] 地球温暖化の影響による亜熱帯地域の感染症拡大に関する疫学研究2007

    • Author(s)
      牧野芳大、江下優樹
    • Publisher
      国立大学法人大分大学環境報告書2008(2007年度)、41pp, 2008年9月大分大学発行
    • Data Source
      KAKENHI-PROJECT-18580310
  • [Journal Article] Molecular evolution of Japanese encephalitis virus isolates from swine in Oita, Japan during 1980-20092010

    • Author(s)
      Wei-feng Tang, Masao Ogawa, Yuki Eshita, Hiroshi Aono, Yoshihiro Makino
    • Journal Title

      Infection, Genetics and Evolution Vol.10(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590588
  • [Journal Article] Molecular epidemiology of dengue virus serotypes 2 and 3 in Paraguay during 2001-2006 : the association of viral clade introductions with shifting serotype dominance2008

    • Author(s)
      Jose D. J. Diaz Aquino, Wei-Feng Tang, Ryoichi Ishii, Tetsuro Ono, Yuki Eshita, Hiroshi Aono and Yoshihiro Makino
    • Journal Title

      Virus Res 137

      Pages: 266-270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18580310
  • [Journal Article] 別府市における輸入デング熱の一症例2007

    • Author(s)
      日隈晴香、中山俊之、江下優樹、牧野芳大、三舟求眞人
    • Journal Title

      日本渡航医学会誌 1

      Pages: 45-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18580310
  • [Journal Article] Shift in Japanese encephalitis virus (JEV) genotype circulating in northern Vietnam : implications for frequent introductions of JEV from southeast Asia to east Asia.2004

    • Author(s)
      Nga PT, Parque MC, Cuong VD, Ma S-P, Hasebe F, Inoue S, Makino Y, Takagi M, Nam VS, MOrita K
    • Journal Title

      Journal of General Virology 85

      Pages: 1625-1625

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590477
  • [Journal Article] Shift in Japanese encephalitis virus (JEV) genotype circulating in northern Vietnam : implications for frequent introductions of JEV from Southeast Asia to East Asia.2004

    • Author(s)
      Nga, PT, Parquet MC, Cuong VD, Ma S-P, Hasebe F., Inoue S., Makino Y., Takagi M, Nam VS, Marita K.
    • Journal Title

      Journal of General Virology 85

      Pages: 1625-1631

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590477
  • [Presentation] Dengue infection's dynamics of vector mosquitoes in the patient's houses, Thailand2008

    • Author(s)
      ESHITA Yuki, Raweewan Srisawat, Narumon Komalamisra, Yupha Rongsriyam, Hiroshi Aono, MAKINO Yoshihiro, Tomohiko Takasaki and Hiroshi Ushijima
    • Organizer
      The Second International conference on Dengue and Dengue Hemorrhagic Fever 2008, "Global Innovation for Combating Dengue Infection"
    • Place of Presentation
      Phuket, Thailand
    • Data Source
      KAKENHI-PROJECT-18580310
  • [Presentation] 蚊類のアルボウイルス媒介能(12)アカイエカ体内における日本脳炎ウイルスの増殖2008

    • Author(s)
      江下優樹, 牧野芳大, 湯偉峰, 青野裕士, 高崎智彦, 田島茂, 高島郁夫, 小林睦生, 倉根一郎
    • Organizer
      第60回日本衛生動物学会大会
    • Place of Presentation
      群馬県
    • Data Source
      KAKENHI-PROJECT-18580310
  • [Presentation] タイ国のデング熱患者宅で採集した蚊のデングウイルス感染2007

    • Author(s)
      江下優樹、Raweewan Srisawat、Narumon Komalamisra、Yupha Rongsriyam、青野裕士、牧野芳大、牛島廣治
    • Organizer
      第48回日本熱帯医学会大会
    • Place of Presentation
      別府市
    • Data Source
      KAKENHI-PROJECT-18580310
  • [Presentation] パラグアイにおけるデングウイルス2・3型の分子疫学、2001-20062007

    • Author(s)
      Diaz Aquino Jose, 湯偉峰、石井竜一、小野哲郎、青野裕士、江下優樹、牧野芳大
    • Organizer
      第48回日本熱帯医学会大会
    • Place of Presentation
      別府市
    • Data Source
      KAKENHI-PROJECT-18580310
  • [Presentation] 別府市における輸入デング熱の一症例2007

    • Author(s)
      日隈晴香、中山俊之、江下優樹、牧野芳大、三舟求眞人
    • Organizer
      第48回日本熱帯医学会大会
    • Place of Presentation
      別府市
    • Data Source
      KAKENHI-PROJECT-18580310
  • 1.  FUKUNAGA Toshihiko (10029796)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  AOKI Kazuo (60201282)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  ZHENG Kuicheng (90315466)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  KATSUMATA Yuriko (00437998)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  ESHITA Yuki (10082223)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 6.  MATSUMOTO Akira (40229539)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  MIZUTANI Tetsuya (70281681)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  IWAMASA Teruo (10110842)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  MIYAGI Koichi (60102274)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  TADANO Masayuki (80179712)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  NIWAT MANEEK
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  CHIRASAK KHA
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  MISUMI Junichi (40109658)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  EBINE Naoyuki (30404370)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TANG Wei-feng (70404382)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  SATO Yoshiya (60092699)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  HOSAKAWA Atsushi (10181497)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  NAKAZATO Iwao (90244318)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  YOSHII Yoshihiko (50110507)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  YAMASHIRO Tetsu (00244335)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SONODA Yoshiko (80253780)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  MA Shao-Ping (50301396)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 23.  新垣 栄 (80264480)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  大鶴 正満 (60018281)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  古閑 比佐志 (30221237)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  銘苅 晋 (50200316)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  田邊 将夫 (30049077)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  安齊 俊一 (20193097)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  KHAMBOONRUANG Chirasak
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  MANEEKARN Niwat
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  SITHISOMBUT ノポーン
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  MANEEKARN Ni
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  CHIOWANICHI ピエン
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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