SASAKI Hiroko 佐々木洋子

Researcher Number	60045424
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Affiliation (based on the past Project Information) *help	2002: Sapporo Medical University, Cancer Research Institute, School of Medicine, Assist.Prof., 附属がん研究所, 講師 2001: 札幌医科大学, 医学部・附属がん研究所, 講師 1999: Cancer Res. Inst., Sch. Of Medicine, Assist. Prof., 医学部・付属がん研究所, 講師 1996 – 1999: 札幌医科大学, 医学部・附属がん研究所, 講師 1998: 札幌医科大学, 附属がん研究所, 講師 … More 1993: 札幌医科大学, 付属がん研究所, 講師 1993: 札幌医科大学, 医学部・付属がん研究所, 講師 1993: Sapporo Medical University, Cancer Research Institute, Assistant Professor, 医学部・付属癌研究所, 講師 1992: 札幌医科大学, 附属癌研究所, 講師 1991: Sapporo Medical College, Cancer Research Institute, Assistant Prof., 癌研究所, 講師 1990: 札幌医科大学癌研究所, 講師 1989: 札幌医科大学, がん研究所, 講師 1987 – 1988: 札幌医科大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Cell biology Except Principal Investigator General medical chemistry
Keywords	Principal Investigator CAKβ / Hic-5 / FAK / タンパク質チロシンキナーゼ / PYK2 / protein-tyrosine kinase / チロシンリン酸化 / 焦点接着 / SH3 domain / nuclear translocation … More / tyrosine-phosphorylation / SH2ドメイン / SH3ドメイン / 核移行 / Focal Adhesion / CAKbeta / focal adhesion kinase / 神経細胞株 / 組み換えレトロウィルス / フォーカル・アドヘジョン・キナーゼ / ポリメラーゼ連鎖反応 / レトロウイルスベクター / 細胞接着斑 / フォーカルアドヘジョンキナーゼ / CBP-1 / 細胞内局在性 / in situ hybridizaion / 免疫組織化学 / パキシリン … More Except Principal Investigator CAKβ / タンパク質チロシンキナーゼ / PYK2 / チロシンリン酸化 / 焦点接着 / Hic-5 / 核移行 / tyrosine-phosphorylation / protein-tyrosine kinase / ホスホリパーゼC / T細胞受容体 / SUMO ligase / nuclear translocation / cDNA発現クローニング / イノシトールリン酸 / CD3複合体 / GFP / SH2ドメイン / 細胞内局在性 / SH3ドメイン / ホスホリパ-ゼC / 細胞内遊離Ca^<2+>濃度 / 血小板由来成長因子 / SH3 domain / アンドロゲン受容体 / Graf / Peptide Mass Fingerprinting法 / SH3 / SH2 domain / cDNA expression cloning / CAKbeta / パキシリン / FAK / GST fusion protein / Src homology 3 domain / バキュロウィルス発現系 / B細胞抗原受容体 / ダブルチロシンモチーフ / Fyn / GST融合タンパク質 / Src相同領域3 / cytoplasmic free Ca^<2+> concentration / recombinant baculovirus / phospholipase C / src homology region 2 / tyrosine phosphorylation / protein tyrosine kinase / T cell receptor / 単クロ-ン抗体 / 可変領域 / 組み換えバキュロウイルス / src相同領域2 / タンパク質チロシンキナ-ゼ / Gタンパク質 / 細胞内遊離カルシウムイオン濃度 / 線維芽細胞 / 細胞内遊離カルシウムイオン濃度。 / ホルボールエステル / コレラ毒素 / T細胞 / OKT3 / GDPβS / GTPγS / フッ化アルミニウム / GTP結合タンパク質 / CBP-1 / in situ hybridization / 免疫組織化学 / 単クローン抗体 / アデノウイルスベクター / Efs / ラスp21タンパク質 / ラス遺伝子 Less

Research Projects
(15 results)
Co-Researchers
(9 People)

Studies on the function of a protein-tyrosine kinase CAKβ/PYK2 and a protein Hic-5 binding to CAKβ
- Principal Investigator
  
  SASAKI Terukatsu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Sapporo Medical University
第二のFAK族チロシンキナーゼCAKβの機能に関する研究
- Principal Investigator
  
  佐々木輝捷
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Sapporo Medical University
FAK族キナーゼCAKβと焦点接着局在Hic-5による細胞形態とJNKの調節機構
- Principal Investigator
  
  佐々木輝捷
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Sapporo Medical University
Studies on the function of Hic-5, a CAKβ-binding protein localized at focal adhesionsPrincipal Investigator
- Principal Investigator
  
  SASAKI Hiroko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Sapporo Medical University
A study on the signaling pathway activating CAKbeta, second protein-tyrosine kinase of the FAK subfamily.
- Principal Investigator
  
  SASAKI Terukatsu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Sapporo Medical University
新たにクローン化したCAKβおよびEfsの細胞接着、分化増殖、癌化における役割
- Principal Investigator
  
  佐々木輝捷
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
新たにクローン化した第2のFAK、CAKβ、の活性化機序とシグナル伝達機構の研究
- Principal Investigator
  
  佐々木輝捷
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Sapporo Medical University
第2のFAK族キナーゼ、CAKβ、のカドヘリンを介するシグナル受容における役割Principal Investigator
- Principal Investigator
  
  佐々木洋子
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Sapporo Medical University
Mechanism of Signal Transduction by Nonreceptor Protein-tyrosine Kinases
- Principal Investigator
  
  SASAKI Terukatsu
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Sapporo Medical University
Establishment of Neural Cell Lines by Introducing cDNA for Immortalization ; Studies on their Surface Antigens and Growth/Differentiation FactorsPrincipal Investigator
- Principal Investigator
  
  SASAKI Hiroko
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Sapporo Medical University
Mechanism of Activation of Signaling Enzymes in Inositol Lipid Metabolism Following Ligation of Cell Surface Receptors in T Lymphocytes
- Principal Investigator
  
  SASAKI Terukatsu
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Sapporo Medical College
PDGF受容体およびT細胞受容体を介するホスホリパ-ゼCの活性化機構
- Principal Investigator
  
  SASAKI Terukatsu
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
T細胞抗原受容体およびNK細胞表面膜受容体を介する細胞内二次シグナルの生成機構
- Principal Investigator
  
  佐々木輝捷
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
PDGF受容体およびT細胞抗原受容体を介するホスホリパーゼCの活性化機構-GTP結合タンパク質の関与しない共役機構の解析-
- Principal Investigator
  
  佐々木輝捷
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University
T細胞抗原受容体およびNK細胞表面膜受容体を介する細胞内二次シグナルの生成機構
- Principal Investigator
  
  佐々木輝捷
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Sapporo Medical University

1. SASAKI Terukatsu (00045494)

# of Collaborated Projects: 14 results

# of Collaborated Products: 0 results
2. ISHINO Masaho (30232325)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. AOTO Hiroshi (30285001)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. YAMASHITA Yumi

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. NAGURA Kazuko

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 遠藤俊明 (90213595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 三高俊広 (50231618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 望月洋一 (40045381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 鈴木るみ子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SASAKI Hiroko 佐々木 洋子

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Studies on the function of Hic-5, a CAKβ-binding protein localized at focal adhesionsPrincipal Investigator

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第2のFAK族キナーゼ、CAKβ、のカドヘリンを介するシグナル受容における役割Principal Investigator

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Establishment of Neural Cell Lines by Introducing cDNA for Immortalization ; Studies on their Surface Antigens and Growth/Differentiation FactorsPrincipal Investigator

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SASAKI Hiroko 佐々木洋子