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HORIGOME Tsuneyoshi  堀米 恒好

ORCIDConnect your ORCID iD *help
… Alternative Names

堀米 恒吉  ホリゴメ ツネヨシ

堀米 恒好  ホリゴメ ツネヨシ

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Researcher Number 60053352
Affiliation (based on the past Project Information) *help 2010 – 2012: 新潟大学, 自然科学系, 教授
2007 – 2008: Niigata University, 自然科学系, 教授
2004 – 2008: 新潟大学, 理学部, 教授
2005: Niigata University, Institute of Science and Technology, Professor, 自然科学系, 教授
1997 – 1999: 新潟大学, 理学部, 助教授
1993 – 1995: 新潟大学, 理学部, 助教授
Review Section/Research Field
Principal Investigator
Cell biology / Cell biology / Applied genomics
Except Principal Investigator
Biological Sciences
Keywords
Principal Investigator
核膜 / ホスホプロテオーム / 核マトリックス / オルガネラ形成 / アフリカツメガエル / 細胞周期 / 核膜形成 / 核移行シグナル結合タンパク質 / 核移行シグナル / 核移行 … More / 核膜タンパク質 / 核膜孔タンパク質 / protein phosphatase 1 / cell cycle / nuclear dynamics / lamin B receptor / emerin / nuclear envelope / 蛋白質リン酸化酵素1 / 自己免疫疾患 / 蛋白質脱リン酸化酵素1 / 核ダイナミクス / ラミンB受容体 / エメリン / Xenopus egg extract. / nuclear envelope precursor vesicle / vesicle fusion / autoimmune disease sera / Nuclear envelope assembly / オルガネラ形式 / 膜融合 / アフリカヅメガエル卵抽出液 / 核膜前駆小胞 / 小胞融合 / 自己免疫血清 / シナル伝達 / シグナル伝達 / リボソーム形成 / WDタンパク質 / 核小体 / 細胞核 / プロテオーム / ホスホプロラオーム / リン酸化ペプチド精製装置 / リン酸化プロテオーム / ホスホプロテオミクス / チタニアカラム / リン酸化ペプチド / RuvBヘリカーゼ / DNAヘリカーゼ / 核膜孔複合体 / mRNA結合蛋白質 / mRNA輸送 / 核外輸送 / 蛋白質核移行 / 核形成 / 核膜小胞 / 核膜孔 / 細胞内トラフィック / 膜透過機構 / タンパク質の核への輸送 / 蛋白質の輸送機構 … More
Except Principal Investigator
モノクローナル抗体 / 染色体 / クロマチンファイバー / マトリックス / 核小体 / 核マトリックス / 核膜再構成 / 核膜孔 / 核内構造タンパク質 Less
  • Research Projects

    (9 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (4 People)
  •  Studies on the inner nuclear structure of the cell based on proteome and phosphoproteome analysesPrincipal Investigator

    • Principal Investigator
      HORIGOME Tsuneyoshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Niigata University
  •  チタニアカラムを用いたハイスループットホスホプロテオーム解析法の開発Principal Investigator

    • Principal Investigator
      堀米 恒好
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Applied genomics
    • Research Institution
      Niigata University
  •  Structural Dynamics of Nucleus: Analysis by Nano-scale Imaging

    • Principal Investigator
      TAKEYASU Kunio
    • Project Period (FY)
      2004 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Nuclear membrane formation and degradation : Cell cycle dependent regulation of the binding of inner nuclear membrane proteins and chromatinPrincipal Investigator

    • Principal Investigator
      HORIGOME Tsuneyoshi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Niigata University
  •  Studies on the mechanism of nuclear envelope reconstitution. - Reconstitution of nuclear envelopes with purified precursor vesicles and analysis of a membrane fusion machinery -Principal Investigator

    • Principal Investigator
      HORIGOME Tsuneyoshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Niigata University
  •  新しい核膜孔複合体蛋白質p50とp39の構造と蛋白質核移行における役割Principal Investigator

    • Principal Investigator
      堀米 恒好
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  アフリカツメガエル卵の系を用いた核膜形成機構に関する研究Principal Investigator

    • Principal Investigator
      堀米 恒好
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Niigata University
  •  核蛋白質の局在化に関与する核膜蛋白質群の蛋白質化学的・免疫化学的研究Principal Investigator

    • Principal Investigator
      堀米 恒好
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  核蛋白質の局在化に関与する核膜蛋白質群の蛋白質化学的・免疫化学的研究Principal Investigator

    • Principal Investigator
      堀米 恒好
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University

All 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Book Patent

  • [Book] 細胞核のダイナミクス(第4章担当)2004

    • Author(s)
      堀米恒好
    • Publisher
      シュプリンガー・フェアラーク東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16570154
  • [Book] 細胞核のダイナミクス"再構成核による核膜の再構成機構の解析"pp87-94(米田悦啓・竹安邦夫偏)2004

    • Author(s)
      堀米 恒好
    • Total Pages
      206
    • Publisher
      シュプリンガー・フェアラーク東京
    • Data Source
      KAKENHI-PROJECT-16570154
  • [Journal Article] Cell Cycle-Dependent Phosphorylation of MAN-1.2009

    • Author(s)
      Y. Hirano, Y. Iwase, K. Ishii, M. Kumeta, T. Horigome & K. Takeyasu
    • Journal Title

      Biochemistry 48

      Pages: 1636-1643

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] A-type and B-type lamins initiate layer assembly at distinct areas of the nuclear envelope in living cells.2009

    • Author(s)
      Kazuya Ishida, Taka-aki Tsunoyama, Suguru Toda, Shinichi Osoda, Tsuneyoshi Horigome, Paul A Fisher, Shin Sugiyama, and Kazuhiro Furukawa
    • Journal Title

      Exp. Cell Res. (In Press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] Nuclear matrix contains novel WD-repeat and disordered-regin-rich proteins.2008

    • Author(s)
      K. Ishii, Y. Hirano, N. Araki, T. Oda, M. Kumeta, K. Takeyasu, K. Furukawa & T. Horigome
    • Journal Title

      FEBS Lett. 582

      Pages: 3515-3519

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] Proteomic and targeted analytical identification of BXDC1 and EBNA1BP2 as dynamic scaffold proteins in the nucleous2008

    • Author(s)
      K. takeyasu, T. Horigome
    • Journal Title

      Genes Cell 14

      Pages: 155-166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] Proteomic and targeted analytical identification of BXDC1 and EBNA1BP2 as dynamic scaffold proteins in the nucleous.2008

    • Author(s)
      Y. Hirano, K. Ishii, M. Kumeta, K. Furukawa, K. Takeyasu & T. Horigome.
    • Journal Title

      Genes Cell 14

      Pages: 155-166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] Nuclear envelope precursor vesicle targeting to chromatin is stimulated by protein phosphatase 1 in Xenopus egg extracts.2007

    • Author(s)
      Ito, H., Koyama, Y., Takano, M., Ishii, K., Maeno, M., Furukawa, K. and T. Horigome
    • Journal Title

      Exp. Cell Res. 313

      Pages: 1897-1910

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] BAF as a Caspase-Dependent Mediator of Nuclear Apoptosis in Drosophila.2007

    • Author(s)
      Kazuhiro Furukawa, Tomoko Aida, Yuki Nonaka, Shinichi Osoda, Candido Juarez, Tsuneyoshi Horigome, Shin Sugiyama
    • Journal Title

      J Struct. Biol. 160

      Pages: 125-134

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] Anti-p97/VCP antibodies : an autoantibody marker for a subset of primary biliary cirrhosis patients with milder disease?2006

    • Author(s)
      Kiyomitsu Miyachi, Hiroo Hosaka, Noriko Nakamura, Hiroshi Miyakawa, Tsuneyo Mimori, Minoru Shibata, Shouzoh Matsushima, Hiroaki Chinoh, Tuneyoshi Horigome, Raleigh W.Hankins, Meifeng Zhang, Marvin J.Fritzler
    • Journal Title

      Scand.J.Immun (印刷中)

    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] Anti-p97/VCP antibodies: an autoantibody marker for a subset of primary biliary cirrhosis patients with milder disease?2006

    • Author(s)
      K. Miyachi, H. Hosaka, N. Nakamura, H. Miyakawa, T. Mimori, M. Shibata, S. Matsushima, H. Chinoh, T. Horigome, Hankins, W. R., Zhang, M., and Fritzler, J. M.
    • Journal Title

      Scand. J. Immun. 63

      Pages: 376-382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] Proteome analysis of rat liver nuclear insoluble protein fraction and localization of a novel protein, ISP36, to compartments in the interchromatin space.2005

    • Author(s)
      Segawa, M., Niino, K., Mineki, R., Kaga, N., Murayama, K., Sugimoto, K., Watanabe, Y., Furukawa, K., Horigome, T
    • Journal Title

      FEBS J 272

      Pages: 4327-4338

    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] Homogeneous assays for single-nucleotide polymorphism genotyping : Exo-proofreading assay based on loop-mediated isothermal amplification.2005

    • Author(s)
      Y. Kuzuhara, T. Yonekawa, M. Iwasaki, T. Kadota, H. Kanda, T .Horigome and T. Notomi
    • Journal Title

      Yokohama Med. J. 56

      Pages: 9-16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] Dissociation of emerin from barrier-to-autointegration factor is regulated through mitotic phosphorylation of emerin in a Xenopus egg cell-free system.2005

    • Author(s)
      Yasuhiro Hirano, Masashi Segawa, Fumiko S.Ouchi, Yoshio Yamakawa, Kazuhiro Furukawa, Kunio Takeyasu, Tsuneyoshi Horigome
    • Journal Title

      J.Biol.Chem 280(48)

      Pages: 39925-39933

    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] Proteome analysis of rat liver, nuclear insoluble protein fraction and localization of a novel protein, ISP36, to compartments in the interchromatin space2005

    • Author(s)
      M. Segawa, K. Niino, R. Mineki, N. Kaga, K. Murayama, K. Sugimoto, Y. Watanabe, K. Furukawa,and T. Horigome
    • Journal Title

      FEBS J. 272

      Pages: 4327-4338

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] Null mutants of Drosophila B-type lamin Dm0 show aberrant tissue differentiation rather than obvious nuclear shape distortion or specific defects during cell proliferation.2005

    • Author(s)
      S. Osouda, Y. Nakamura, de Saint Phalle, B. McConnell, B., T. Horigome, S. Sugiyama, Fisher, P.A. and K. Furukawa
    • Journal Title

      Dev. Biol. 284

      Pages: 219-232

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] Dissection of Emerin from barrier-to-autointegration factor is regulated through mitotic phosphorylation of Emerin in a Xenopus egg cell-free system.2005

    • Author(s)
      Y. Hirano, M. Segawa, F. S. Ouchi, Y. Yamakawa, K. Furukawa, K. Takeyasu & T. Horigome
    • Journal Title

      J. Biol. Chem. 280

      Pages: 39925-39933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16084203
  • [Journal Article] Autoantigens of the nuclear pore complex2004

    • Author(s)
      P.Enarson, J.B.Rattner, Y.Ou, K.Miyachi, T.Horigome, M.Fritzler
    • Journal Title

      J.Mol.Med. 82

      Pages: 423-433

    • Data Source
      KAKENHI-PROJECT-16084203
  • [Patent] リン酸化ペプチドの精製方法及び精製装置2008

    • Inventor(s)
      堀米恒好岩瀬由佳
    • Industrial Property Rights Holder
      新潟大学
    • Industrial Property Number
      2008-122156
    • Filing Date
      2008-05-08
    • Data Source
      KAKENHI-PROJECT-19651085
  • [Patent] チタニアカラム利用天然試料由来のリン酸化ペプチド精製法2007

    • Inventor(s)
      堀米恒好
    • Industrial Property Rights Holder
      堀米恒好
    • Acquisition Date
      2007-09-21
    • Data Source
      KAKENHI-PROJECT-19651085
  • [Presentation] チタニアカラムを用いた全自動リン酸化ペプチド精製法の改良と応用2008

    • Author(s)
      堀米恒好, 他4名
    • Organizer
      日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19651085
  • [Presentation] チタニアカラムを用いた全自動リン酸化ペプチド精製装置の開発2007

    • Author(s)
      堀米恒好, 他4名
    • Organizer
      第80回日本生化学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-12
    • Data Source
      KAKENHI-PROJECT-19651085
  • 1.  TAKEYASU Kunio (40135695)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 2.  YOSHIMURA Shigehiro (90346106)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  HIZUME Kohji (10378846)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  FURUKAWA Kazuhiro (40229109)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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