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IMAI Takasuke  今井 孝祐

ORCIDConnect your ORCID iD *help
… Alternative Names

今井 孝祐  イマイ タカスケ

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Researcher Number 60091964
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2007 – 2008: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 教授
2006: 東京医科歯科大学, 大学院医歯学総合研究科, 教授
2005: 東京医科歯科大学, 大学院・医歯学総合研究科, 教授
1999 – 2001: 東京医科歯科大学, 大学院・医歯学総合研究科, 教授
1996 – 1997: 群馬大学, 医学部, 助教授 … More
1993: 群馬大学, 医学部, 助教授
1990: 群馬大学, 医学部, 助教授
1988: 群馬大学, 医学部附属病院救急部, 助教授 Less
Review Section/Research Field
Principal Investigator
Anesthesiology/Resuscitation studies / Emergency medicine / 麻酔学
Keywords
Principal Investigator
肺循環 / TNF / サイトカイン / RT-PCR / mRNA / IL-6 / 遊離肺還流標本 / 虚血・再還流障害 / isolated perfused lung / 生理学 … More / 低酸素症 / inflammatory cytokines / unilateral ischemia / cyotokine / isolated rat lung / ischemia-reperfusion / 遊離潅流肺標本 / 虚血・再潅流障害 / IL-1 beta / 虚血・再環流障害 / 肺遊離環流標本 / Interferon-γ / Inteferon-γ / IL-10 / 好炎症性サイトカイン / sepsis / ketamine / halothane / anesthesia / endotoxin / IL-1 / Northern blot / tumornecrosis factor / エンドトキシン抵抗性 / ケタミン / ハロタン / 生存率 / 盲腸結紮穿刺 / 敗血症 / エンドトキシン / 呼気終末陽圧 / 過換気 / 肺高血圧 / 血小板活性化因子 / 肺血管床透過性 / TNF-alpha / BAL / cytokine / lung edema / CPAP / hyperventilation / 遊離環流肺標本 / 人工呼吸 / 遺伝子 / immunofluorecence / in situ hybridization / 炎症性サイトカイン / 血管内圧 / 肺血管内皮細胞 / remote organ damage / lung-lung interaction / TNF-α converting enzyme / tumor necrosis factor-α / ischemia reperfusion injury / 虚血再還流障害 / 細胞・組織 / 移植・再生医療 / 虚血再環流傷害 / 組織 / 細胞 / 再生医療 / 移植 / 遊離還流肺標本 / 再還流障害 / 虚血 / 炭酸ナトリウム / 重炭酸ナトリウム / 酸ー塩基平衡 / 高エネルギ-燐酸化合物 / 細胞内pH / NMR Less
  • Research Projects

    (7 results)
  • Research Products

    (39 results)
  • Co-Researchers

    (4 People)
  •  過大一回換気量による肺組織でのサイトカイン遺伝子発現と他臓器障害の機序解明Principal Investigator

    • Principal Investigator
      今井 孝祐
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Elucidation of the mechanism of ischemia/reperfusion injury of the lung and development of preventive and therapeutic maneuversPrincipal Investigator

    • Principal Investigator
      IMAI Takasuke
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Tokyo Medical and Dental University
  •  Elucidation of pathophysiology of ischemia reperfusion injury jn isolated perfused rat lungsPrincipal Investigator

    • Principal Investigator
      IMAI Takasuke
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Tokyo Medical & Dental University
  •  Effect of different anesthetics and anesthetic exposure times on survival course of sepsis-analysis of mRNA in mice performed cecal ligation & puncture-Principal Investigator

    • Principal Investigator
      IMAI Takasuke
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Gunma University
  •  遊離還流肺における片側,虚血-再還流傷害モデルの作製と肺再還流傷害機序の解明Principal Investigator

    • Principal Investigator
      今井 孝祐
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Gunma University
  •  低心拍出状態での細胞外液の至適pHに関する研究ー重炭酸ナトリウム,炭酸ナトリウム投与の効果のNMRによる検索ーPrincipal Investigator

    • Principal Investigator
      今井 孝祐
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      Gunma University
  •  ラット遊離肺還流モデルにおける白血球、PAF、TNFの肺血管床透過性亢進への関与Principal Investigator

    • Principal Investigator
      今井 孝祐
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      Gunma University

All 2009 2008 2007 2006 2005

All Journal Article Presentation Book

  • [Book] 展望集中治療医学2008

    • Author(s)
      今井孝祐
    • Total Pages
      239
    • Publisher
      秀潤社
    • Data Source
      KAKENHI-PROJECT-18659531
  • [Book] 展望集中治療医学2008

    • Author(s)
      今井孝祐
    • Total Pages
      239
    • Publisher
      秀潤社
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Journal Article] Salavage of nonischemic control lung from injury by unilateral ischemic lung with apocynin, a nicotinamide adenine dinucleotide phosphate(NADPH)oxidase inhibitor, in isolated perfused rat lung2008

    • Author(s)
      Chenting Zhu, Aishan Bilali, Gabriela S Georgieva, Shunichi Kurata, Chieko Mitaka, Takasuke Imai
    • Journal Title

      Translationa Research 152

      Pages: 273-282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Journal Article] Ameliorating effect of combination of apocynin and TACEI on ischemia/reperfusion (I/R) injury2007

    • Author(s)
      Bilali Aishan, Chenting Zhu, Gabriela Georgieva, 倉田俊一, 今井孝祐
    • Journal Title

      日本集中治僚医学会雑誌 2007;14 : S277 14

    • Data Source
      KAKENHI-PROJECT-18659531
  • [Journal Article] Nonischemic lung injury by mediators from unilateral ischemic reperfused lung : ameliorating effect of tumor necrosis factor-α-converting enzyme inhibitor2007

    • Author(s)
      Gabriela S Georgieva, Shunichi Kurata, Satoshi Ikeda, Yoshinobu Eishi, Chieko Mitaka, Takasuke Imai
    • Journal Title

      SHOCK 27

      Pages: 84-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Journal Article] Induction of cytokine mRNA and edema in isolated perfused unilateral hyperventilated rat lung2007

    • Author(s)
      Bilali Aishan, Chenting Zhu, Gabriela Georgieva, 倉田俊一, 今井孝祐
    • Journal Title

      日本集中治療医学会雑誌 14

    • Data Source
      KAKENHI-PROJECT-18659531
  • [Journal Article] Nonischemic lung injury by mediators from unilateral ischemic reperfused lung : Ameliorating effect of tumor necrosis factor-α-converting enzyme inhibitor2007

    • Author(s)
      Gabriela S Georgieva, Shunichi Kurata, Satoshi Ikeda, Ypshinobu Eishi, Chieko Mitaka, Takasuke Imai
    • Journal Title

      SHOCK 27

      Pages: 84-90

    • Data Source
      KAKENHI-PROJECT-17390481
  • [Journal Article] Nonischemic lung injury by mediators from unilateral ischemic reperfused lung : Ameliorating effect of tumor necrosis factor-a-converting enzyme inhibitor2007

    • Author(s)
      Gabriela S Georgieva, Shunichi Kurata, Satoshi Ikeda, Yoshinobu Eishi, Chieko Mitaka, Takasuke Imai
    • Journal Title

      SHOCK 27

      Pages: 84-90

    • Data Source
      KAKENHI-PROJECT-18659531
  • [Journal Article] High tidal volume (TV) ventilation induced cytokine mRNA and edema in hyperventilated lung in isolated perfused unilateral hyperventilated lung2006

    • Author(s)
      Aishan Bilali, Chenting Zhu, Gabriela S Georgieva, Shunichi Kurata, Takasuke Imai
    • Journal Title

      Crit Care Med 34

    • Data Source
      KAKENHI-PROJECT-18659531
  • [Journal Article] Ameliorating effect of combination of NADPH oxidase inhibitor (Apocynin) and TNF-α converting enzyme inhibitor (TACEI) on ischemia/reperfusion injury2006

    • Author(s)
      Chentin Zhu, Aishan Bilali, Gabriela S Georgieva, Shunichi Kurata, Takasuke Imai
    • Journal Title

      Crit Care Med 34

    • Data Source
      KAKENHI-PROJECT-17390481
  • [Journal Article] Ameliorating effect of combination of NADPH oxidase inhibitor (Apocynin) and TNF-a converting enzyme inhibitor (TACEI) on ischemia/reperfusion injury2006

    • Author(s)
      Chenting Zhu, Aishan Bilali, Gabriela S Georgieva, Shunichi Kurata, Takasuke Imai
    • Journal Title

      Crit Care Med 34

    • Data Source
      KAKENHI-PROJECT-18659531
  • [Journal Article] Prevention of ischemia reperfusion injury by positive pulmonary venous pressure in isolated rat lung2006

    • Author(s)
      Gabriela S Georgieva, Shunichi Kurata, Satoshi Ikeda, Shu Teng, Iyoko Katoh, Yoshinobu Eishi, Chieko Mitaka, Takasuke Imai
    • Journal Title

      SHOCK 25

      Pages: 66-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Journal Article] High tidal volume (TV) ventilation induced cytokine mRNA and edema in hyperventilated lung in isolated perfused unilateral hyperventilated lung2006

    • Author(s)
      Aishan Bilali, Chenting Zhu, Gabriela S Georgieva, Shunichi Kurata, Takasuke Imai
    • Journal Title

      Crit Care Med 34

    • Data Source
      KAKENHI-PROJECT-17390481
  • [Journal Article] Prevention of ishcmia reperfusion injury by positive pulmonary venous pressuree in isolated rat lung2006

    • Author(s)
      Gabriela S Georgieva, Shunichi Kurata, Satoshi Ikeda, Shu Teng, Iyoko Katoh, Yoshinobu Eishi, Chieko Mitaka, Takasuke Imai
    • Journal Title

      SHOCK 25

      Pages: 66-72

    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] TNF-α induction on respiratory epithelium in isolated, unilaterally hyperventilated rat lung2009

    • Author(s)
      Aishan Bilali, Satoshi Ikeda, Shunichi Kurata, Takasuke Imai
    • Organizer
      第36回日本集中治療医学会学術集会
    • Place of Presentation
      大阪国際会議場、大阪
    • Year and Date
      2009-02-26
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Induction of TNF-α on respiratory epithelium in unilateral hyperventilated lung an increased permeability by the recirculated perfusate in control lung maintained at CPAP(2.5 cmH20)in isolated, separately ventilated, perfused rat lung2009

    • Author(s)
      Aisha Bilali, Chenting Zhu, Gabriela Georgieva, Shunichi Kurata, Satoshi Ikeda, Takasuke Imai
    • Organizer
      38^<th> Critical Care Congress
    • Place of Presentation
      Gaylord Opryland Resort and Convention Center, Nahville, Tennessee, USA
    • Year and Date
      2009-02-01
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Polymyxin B-immobilized fiber column hemoperfusion has the possibility to reduce endothelial activation in patients with septic shock2008

    • Author(s)
      Chieko Mitaka, Ymi Fujii, Yasuaki Nakajima, Kenrou Kawada, TakasukeImai
    • Organizer
      Society of Critical Care Medicine's 37th Critical Care Congress
    • Place of Presentation
      Hawaii Convention Center, Honolulu, Hawaii, USA
    • Year and Date
      2008-02-03
    • Data Source
      KAKENHI-PROJECT-18659531
  • [Presentation] Injury of CPAP lung by mediators from isolated perfused unilateral hyperventilated rat lung2008

    • Author(s)
      Bilali Aishan, Zhu Chenting, Georgieva S Gabriela, Kurata Shunichi, Imai Takasuke
    • Organizer
      第35回日本集中治療医学会
    • Place of Presentation
      京王プラザホテル、東京
    • Year and Date
      2008-02-14
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Injury of CPAP lung by mediators from isolated perfused unilateral hyperventilated rat lung2008

    • Author(s)
      Aishan Bilali, Chenting Zhu, Gabriela S Georgieva, Takasuke Imai
    • Organizer
      37^<th> Critical Care Congress
    • Place of Presentation
      Hawaii Convention Center, Honolulu, Hawaii, USA
    • Year and Date
      2008-02-03
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] The effect of TNF-a on microvascular permeability in an isolated perfused lung2008

    • Author(s)
      Georgieva Gabriela S, Kurata Shunichi, Bilali Aishan, Zhu Chengting, Imai Takasuke
    • Organizer
      第35回日本集中治療医学会学術集会
    • Place of Presentation
      東京新宿京王プラザホテル
    • Year and Date
      2008-02-14
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Injury of CPAP lung by mediators from isolated perfused unilateral hyperventilated rat lung2008

    • Author(s)
      Bilali Aishan, Zhu Chenting, Georgieva Gabriela S, Kurata Shunichi, Imai Takasuke
    • Organizer
      第35回日本集中治療医学会学術集会
    • Place of Presentation
      東京新宿京王プラザホテル
    • Year and Date
      2008-02-14
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Injury of CPA lung by mediators from isolated perfused unilateral hyperventilated rat lung2008

    • Author(s)
      Aishan Bilali, Chenting Zhu, Gabriela S Georgieva, TakasukeImai Takasuke
    • Organizer
      Society of Critical Care Medicine's 37th Critical Care Congress
    • Place of Presentation
      Hawaii Convention Center, Honolulu, Hawaii, USA
    • Year and Date
      2008-02-03
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Polymyxin B-immobilized fiber column hemoperfusion has the possibility to reduce endothelial activation in patients with septic shock2008

    • Author(s)
      Chieko Mitaka, Ymi Fujii, Yasuaki Nakajima, Kenrou Kawada, Takasuke Imai
    • Organizer
      Society of Critical Care Medicine's 37th Critical Care Congress
    • Place of Presentation
      Hawaii Convention Center, Honolulu, Hawaii, USA
    • Year and Date
      2008-02-03
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] The effect of TNF-α on microvascular permeability in an isolated perfused lung2008

    • Author(s)
      Georgieva Gabriela S, Kurata Shunichi, Bilali Aishan, Zhu Chengting, Imai Takasuke
    • Organizer
      第35回日本集中治療医学会
    • Place of Presentation
      京王プラザホテル、東京
    • Year and Date
      2008-02-14
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Injury of CPAP Iung by mediators from isolated perfused unilateral hyperventilated rat lung2008

    • Author(s)
      Bilali Aishan, Zhu Chenting, Georgieva Gabriela S, Kurata Shunichi, Imai Takasuke
    • Organizer
      第35回日本集中治療医学会学術集会
    • Place of Presentation
      東京新宿京王プラザホテル
    • Year and Date
      2008-02-14
    • Data Source
      KAKENHI-PROJECT-18659531
  • [Presentation] The effect of TNF-a on microvascular permeability in an isolated perfused lung2008

    • Author(s)
      Georgieva Gabriela S, Kurata Shunichi, Bilali Aishan, Zhu Chengting, Imai Takasuke
    • Organizer
      第35回日本集中治療医学会学術集会
    • Place of Presentation
      東京新宿京王プラザホテル
    • Year and Date
      2008-02-14
    • Data Source
      KAKENHI-PROJECT-18659531
  • [Presentation] Injury of CPA lung by mediators from isolated perfused unilateral hyperventilated rat lung2008

    • Author(s)
      Aishan Bilali, Chenting Zhu, Gabriela S Georgieva, TakasukeImai Takasuke
    • Organizer
      Society of Critical Care Medicine's 37th Critical Care Congress
    • Place of Presentation
      Hawaii Convention Center, Honolulu, Hawaii, USA
    • Year and Date
      2008-02-03
    • Data Source
      KAKENHI-PROJECT-18659531
  • [Presentation] Unilateral ischemic lung induces contralateral lung injury by liberating mdiators in cirulation Symposium "Acute Respiratory Failure and remote organ damage"2008

    • Author(s)
      Gabriela S Georgieva, Shunichi Kurata, Aisan Bilari, Chenting Zhu, Takasuke Imai
    • Organizer
      第35回日本集中治療医学会学術集会
    • Place of Presentation
      京王プラザホテル、東京
    • Year and Date
      2008-02-16
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Unilateral ischemic lung induces contralateral lung injury by liberating mediators in circulation2008

    • Author(s)
      Gabriela S Georgieva, Shunichi Kuata, Aisan Bilari, Chenting Zhu, TakasukeImai Takasuke
    • Organizer
      弟35回日本集中治療医学会学術集会シンボジウム Acute Respiratory failure and remote organ damage
    • Place of Presentation
      東京新宿京王プラザホテル
    • Year and Date
      2008-02-16
    • Data Source
      KAKENHI-PROJECT-18659531
  • [Presentation] Ameliorating effect of combination of NADPH oxidase inhibitor(Apocynin)and TNF-α converting enzyme inhibitor(TACEI)on ishcmeia/reperfusion injury2007

    • Author(s)
      Chenting Zhu, Aishan Bilali, Gabriela S Georgieva, Shunichi Kurata, Takasuke Imai
    • Organizer
      36^<th> Critical Care Congress
    • Place of Presentation
      Gaylord Palms Resort and Cponvention Center Orlando, Florida, USA
    • Year and Date
      2007-02-18
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Ameliorating effect of combination of apocynin and TACEI on ischemia/reperfusion(I/R)injury2007

    • Author(s)
      Chenting Zhu, Bilali Aishan, Gabriela Georgieva, Shunichi Kurata, Takasuke Imai
    • Organizer
      第34回日本集中治療医学会学術集会
    • Place of Presentation
      神戸国際展示場、神戸
    • Year and Date
      2007-03-02
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] High tidal volume(TV)ventilation induced cytokine mRNA and edema in hyperventilated lung in isolated perfused unilateral hyperventilated lung2007

    • Author(s)
      Aishan Bilali, Chenting Zhu, Gabriela S Georgieva, Shunichi Kurata, Takasuke Imai
    • Organizer
      36^<th> Critical Care Congress
    • Place of Presentation
      Gaylord Palms Resort and Cponvention Center Orlando, Florida, USA
    • Year and Date
      2007-02-18
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Effect of positive(5 mmHg)pulmonary venous pressure on isolated ischemic-reperfused rat lungs maintained at CPAP2007

    • Author(s)
      Georgieva GS, Kurata S, Zhu C, Bilali A, Imai T
    • Organizer
      20^<th> Annual Congress of European Society of Intensive Care Medicine
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2007-10-08
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Induction of cytokine mRNA and edema in isolated perfused unilateral hyperventilated rat lung2007

    • Author(s)
      Bilali Aishan, Chenting Zhu, Gabriela Georgieva, Shunichi Kurata, Takasuke Imai
    • Organizer
      第34回日本集中治療医学会学術集会
    • Place of Presentation
      神戸国際展示場、神戸
    • Year and Date
      2007-03-02
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Tumor necrosis factor-α converting enzyme inhibitor(TACEI)ameliorates control right lung(RL)injury by humoral mediators liberated from unilateral ischemia/reperfused(I/R)left lung(LL)2006

    • Author(s)
      Gabriela S Georgieva, Takasuke Imai, Shunichi Kurata
    • Organizer
      35^<th> Critical Care Congress
    • Place of Presentation
      Moscone west convention center, SF, CA, USA
    • Year and Date
      2006-01-08
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] TNF-α converting enzyme inhibitor(TACEI)decreases control right lung injury induced by I/R left lung2006

    • Author(s)
      Gabriela S Georgieva, Takasuke Imai
    • Organizer
      第33回日本集中治療医学会学術集会
    • Place of Presentation
      大阪国際会議場、大阪
    • Year and Date
      2006-03-02
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Development of a novel model for high tidal volume lung injury2006

    • Author(s)
      Aishan Bilali, Chenting Zhu, Georgieva Gabriela, Shunichi Kurata, Takasuke Imai
    • Organizer
      第34回日本救急医学会学術集会
    • Place of Presentation
      福岡国際会議場、福岡
    • Year and Date
      2006-10-30
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Amelioration of ischemia-reperfusion(I/R)injury by NADPH oxidase inhibitor in isolated perfused rat lung2006

    • Author(s)
      Chenting Zhu, Asahn Bilali, Gabriela S Georgieva, Shunichi Kurata, Takasuke Imai
    • Organizer
      第34回日本救急医学会学術集会
    • Place of Presentation
      福岡国際会議場、福岡
    • Year and Date
      2006-10-30
    • Data Source
      KAKENHI-PROJECT-17390481
  • [Presentation] Ischemic reperfused left lung(LL)increases expression of inflammatory cytokines mRNA in the control right lung(RL)2005

    • Author(s)
      Gabriela S Georgieva, Takasuke Imai, Shunichi Kurata
    • Organizer
      第33回日本救急医学会学術集会
    • Place of Presentation
      大宮ソニックシテイ、大宮
    • Year and Date
      2005-10-27
    • Data Source
      KAKENHI-PROJECT-17390481
  • 1.  KURATA Shyunichi (60140901)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 30 results
  • 2.  江石 義信 (70151959)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 3.  NOSAKA Toshihisa (20313257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  MITAKA Chieko (20126254)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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