• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

HASHIZUME Kiyoshi  橋爪 潔志

ORCIDConnect your ORCID iD *help
Researcher Number 60092889
Affiliation (based on the past Project Information) *help 2003 – 2006: 信州大学, 大学院・医学研究科, 教授
1998 – 1999: 信州大学, 医学部, 教授
1993: 信州大学, 医学部, 教授
1993: Shinshu University, Medicine, Professor, 医学部・老年医学教室, 教授
1993: Shinshu Univ.Dept of Geriatrics, Professor, 医学部・附属病院老年科, 教授 … More
1992: 信州大学, 医学部・老年科
1992: 信州大学, 医学部・老年科, 教授
1992: 信州大学, 医学部附属病院, 教授
1991: 信州大学, 医学部・附属病院, 講師
1991: Department of Geriatrics, Shinshu University School of Medicine Associate Professor, 医学部附属病院・老年科, 講師
1990 – 1991: 信州大学, 医学部・附属病院・老年科, 講師
1990: 信州大学, 医学部附属病院老年科, 講師
1989: 信州大学, 医学部・附属病院, 講師
1988: Associate Proffesor, Department of Geriatrics, Endocrinology and Metabolism, Shinshu University School of Medicine, 医学部附属病院老年科, 講師
1987 – 1988: 信州大学, 医学部附属病院・老年科, 講師
1986: 信大, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
内分泌・代謝学 / Endocrinology / Endocrinology
Except Principal Investigator
内分泌・代謝学
Keywords
Principal Investigator
NADPH / 甲状腺ホルモン / CTBP / 甲状腺ホルモン受容体 / NADP / CRYM / 細胞分化 / thyroid hormone / 核受容体 / 甲状腺ホルモン結合蛋白 … More / 遺伝子発現 / クリスタリン / ノックアウトマウス / 甲状腺ホルモン核受容体 / 細胞質甲状腺ホルモン結合蛋白 / 分化 / 受容体 / Counterregulation / nuclear T_3 receptor / Acceptor protein / Cytosolic 3,5,3'-triiodo-L-thyronine(T_3)-binding protein(CTBP) / 情報処理機構 / リボシレーション / DNA修復 / 活性型および非活性型受容体 / ホルモン能態輸送 / 核基質 / ADPリボシレーション / 受容体受容蛋白 / 細胞核受容体 / 細胞質受容体 / 遣伝子発現調節 / counterregulation / アクセプタープロテイン / T_3 / 3,5,3'-triiodo-L-thyronine / knockout mouse / ABR / mu-crystallin / 難聴 / 細胞質甲状腺ホルモン結合 / Cell cycle / transcription factor / アポトーシス / 細胞周期 / 転写因子 / Vitamin D / Thyroid hormone-binding protein / Differentiation / Decarcinogenesis / Thyroid hormone receptor / Nuclear receptor(s) / ビタミンD / 脱癌化 / Gene expression / Nuclear protein kinase / Cytosolic T3-binding protein (CTBP) / Thyroid hormone nuclear receptor / Acceptor蛋白 / 情報伝達因子 / ホルモン情報 / 細胞質甲状腺ホルモン結合物質 / 転写開始シグナル / 核リン酸化酵素 / 核リン酸化酷素 / トリヨードサイロニン / 増殖 / 細胞増殖 / cーerb A … More
Except Principal Investigator
T3 responsive element / dRLh-84 cell / Cell proliferation / Nuclear T3 receptor / Cell cycle / cellular T3 transport / Peroxisome / Thryoid hormone / 大腸菌発現ベクタ- / インスリン / 細胞格甲状腺ホルモン受容体 / malic enzyme / Non thyroidal illness / 大腸菌発現ベクター / 細胞質T3結合蛋白質 / 細胞核甲状腺ホルモン受容体 / リンゴ酸酵素 / 糖尿病 / 核T_3受容体 / 細胞内T_3輸送 / dRLh-84 / 細胞増殖 / 核T3受容体 / 細胞周期 / 細胞内T3輸送 / T3 reponsive element / ペルオキシゾーム / 甲状腺ホルモン Less
  • Research Projects

    (9 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (3 People)
  •  Multiple physiological roles of cytosolic 3,5,3'-triiodothyronine binding protein (CTBP)Principal Investigator

    • Principal Investigator
      HASHIZUME Kiyoshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Shinshu University
  •  細胞質甲状腺ホルモン結合蛋白の甲状腺ホルモンによる生体調節機能における役割の解析Principal Investigator

    • Principal Investigator
      橋爪 潔志
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Shinshu University
  •  The mechanism of cell cycle regulation by thyroid hormonePrincipal Investigator

    • Principal Investigator
      HASHIZUME Kiyoshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Shinshu University
  •  転写因子としての甲状腺ホルモン受容体による機能分化と細胞増殖調節の解析Principal Investigator

    • Principal Investigator
      橋爪 潔志
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Shinshu University
  •  A Study of Differential Actions of Thyroid Hormone in Its TargetPrincipal Investigator

    • Principal Investigator
      HASHIZUME Kiyoshi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Shinshu University
  •  Analysis of thyroid hormone action in the cell ; Mechanism of induction and function of the hormone-responsive protein.

    • Principal Investigator
      ICHIKAWA Kazuo
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Shinshu University
  •  転写因子としての甲状腺ホルモン受容体による機能分化と細胞増殖調節の解析Principal Investigator

    • Principal Investigator
      橋爪 潔志
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Shinshu University
  •  Studies on the regulation of nuclear receptor which controls the gene expressionPrincipal Investigator

    • Principal Investigator
      HASHIZUME Kiyoshi
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Department of Geriatrics, Shinshu University School of Medicine
  •  Studies on the hormone action at the target tissues: Activation of receptor and metabolism of DNAPrincipal Investigator

    • Principal Investigator
      HASHIZUME Kiyoshi
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Shinshu University School of Medicine

All 2007 2006

All Journal Article

  • [Journal Article] CRYM as an intracellular T3 holder in vivo.2007

    • Author(s)
      Suzuki S, Suzuki N, Mori JI, Oshima A, Usami S, Hashizume K
    • Journal Title

      Mol Endocrinol 21

      Pages: 885-894

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590957
  • [Journal Article] μ-crystallin as an intracellular 3,5,3' triiodothyronine holder in vivo2007

    • Author(s)
      S.Suzuki, N.Suzuki, Jun-ichirou Mori, A.Oshima, S.Usami, K.Hashizume
    • Journal Title

      Molecular Endocrinology 21

      Pages: 885-894

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590957
  • [Journal Article] Synergistic regulation of the mouse orphan nuclear receptor SHP gene promoter by CLOCK-BMAL1 and LRH-12006

    • Author(s)
      Oiwa A, Kakizawa T, Miyamoto T, Yamashita K, JiangW, Takeda T, Suzuki S, Hashizume K
    • Journal Title

      Biochem Biophys Res Commun 353

      Pages: 895-901

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590957
  • [Journal Article] CRYM mutations cause deafness through thyroid hormone binding properties in the fibrocytes of the cochlea.2006

    • Author(s)
      Oshima A, Suzuki S, Takumi Y, Hashizume K, Abe S, Usami S
    • Journal Title

      J Med Genet 43

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590957
  • [Journal Article] Inhibition of LXRalpha signaling by vitamin D receptor : possible role of VDR in bile acid synthesis2006

    • Author(s)
      Jiang W, Miyamoto T, Kakizawa T, Nishio SI, Oiwa A, Takeda T, Suzuki S, Hashizume K
    • Journal Title

      Biochem Biophys Res Commun 351

      Pages: 176-184

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590957
  • [Journal Article] Endocrinological aspects of aging : Adaptation to and acceleration of aging by the endocrine system.2006

    • Author(s)
      Hashizume K, Suzuki S, Takeda T, Shigematsu S, Ichikawa K, Koizumi Y
    • Journal Title

      Geriatr Gerontol Int 6

      Pages: 1-6

    • NAID

      10017615757

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590957
  • [Journal Article] Metobolic syndrome and age-related dementia : endocrinological aspects of adaptation to aging.2006

    • Author(s)
      Hashizume K, Suzuki S, Hara M, Komatsu A, Yamashita K
    • Journal Title

      Mech Ageing Dev 127

      Pages: 507-510

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590957
  • [Journal Article] Synergistic regulation of the mouse orphan nuclear receptor SHP gene promoter by CLOCK-BMAL and LRH-12006

    • Author(s)
      Oiwa A, Kakizawa T, Miyamoto T, Yamashita K, Jiang W, Takeda T, Suzuki S, Hashizume K
    • Journal Title

      Biochem Biophys Res Commun 353

      Pages: 895-901

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590957
  • [Journal Article] Metabolic syndrome and age-related dementia : Endocrinological aspects of adaptation to aging2006

    • Author(s)
      Hashizume K, Suzuki S, Hara M, Komatsu A, Yamashita K
    • Journal Title

      Mech Ageing Dev 127

      Pages: 507-510

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590957
  • [Journal Article] CRYM mutations cause deafness through thyroid hormone binding properties in the fibrocytes of the cochlea.2006

    • Author(s)
      A.Oshima, S.Suzuki, Y.Takumi, K.Hashizume, S.Abe, S.Usami
    • Journal Title

      Journal of Medical Genetics (in press)

    • Data Source
      KAKENHI-PROJECT-17590957
  • [Journal Article] Endocrinological aspects of aging : adaptation to and acceleration of aging by the endocrine system2006

    • Author(s)
      Hashizume K, Suzuki S, Takeda T, Shigematsu S, Ichikawa K, Koizumi Y
    • Journal Title

      Geriatr Gerontrol Int 6

      Pages: 1-6

    • NAID

      10017615757

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590957
  • [Journal Article] Inhibition of LXRalpha signaling by vitamin D receptor : possible role of VDR in bile acid synthesis.2006

    • Author(s)
      Jiang W, Miyamoto T, Kakizawa T, Nishio SI, Oiwa A, Takeda T, Suzuki S, Hashizume K
    • Journal Title

      Biochem Biophy Res Commun 351

      Pages: 176-184

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590957
  • 1.  ICHIKAWA Kazuo (40159835)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  SUZUKI Satoru (30222061)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 12 results
  • 3.  山内 恵史 (30191191)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi