KAMESHITA ISAMU 亀下勇

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Kameshita Isamu 亀下勇

KAMESHITA Isamu 亀下勇

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Researcher Number	60127941
Other IDs
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Affiliation (based on the past Project Information) *help	2017: 香川大学, 農学部, 教授 2013 – 2015: 香川大学, 農学部, 教授 2009 – 2011: Kagawa University, 農学部, 教授 2000 – 2006: 香川大学, 農学部, 教授 2001: Asahikawa Medical College, Biochemistry, Assistant Professor, 医学部, 助教授 1988 – 1999: Asahikawa Medical College ・ Associate Professor, 医学部, 助教授
Review Section/Research Field	Principal Investigator Chemistry related to living body / General medical chemistry / Structural biochemistry / 代謝生物化学 / Chemical biology / Living organism molecular science Except Principal Investigator General medical chemistry / Applied molecular and cellular biology / Structural biochemistry / Biological Sciences / Pathological medical chemistry / Pathological medical chemistry / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator プロテインキナーゼ / Protein kinase / タンパク質リン酸化反応 / Signal transduction / Protein phosphorylation / Calmodulin / 情報伝達 / 中枢神経 / 蛋白質リン酸化反応 / カルモデュリン … More / 活性制御機構 / プロテインホスファターゼ / タンパク質リン酸化 / 細胞内情報伝達 / 二次元電気泳動 / モノクローナル抗体 / バイオテクノロジー / シグナル伝達 / Biotechnology / Monoclonal antibody / Proteome / プロテオーム / cDNA cloning / enzyme regulation / Calmodulin-dependent protein kinase / Protein phosphatase / 基質特異性 / ホスホペプチド / 細胞内局在 / ポリカチオン / 変異酵素 / カルモデュリンキナーゼ / Central Nervous System / Signal Transduction / Protein Phosphorylation / Protein Kinase / 神経機能 / Central nervous system / シナプス接合部 / プロティンキナ-ゼ / プロティンキナーゼ / 蛍光発生基質 / 酸化還元 / インゲルアッセイ / 活性制御因子 / ツーハイブリッドスクリーニング / プロテインキナーゼカスケード / 翻訳後修飾 / カルモジュリンキナーゼ / 糖尿病 / インスリン分泌 / 胚発生 / ゼブラフィッシュ / キノコ / 網羅的解析 / プロテオミクス / 生体機能関連物質 … More Except Principal Investigator カルモデュリン / シグナル伝達 / カルシウムイオン / 自己燐酸化 / 蛋白質燐酸化酵素 / 脳 / チロシン水酸化酵素 / カルモデュリン依存性蛋白質燐酸化酵素 / CaM kinase / CaMキナーゼIV / Calcium ion / CaM-kinase IV / CaM-kinase II / Calmodulin / Autophosphorylation / Tyrosine Hydroxylase / Brain / 中枢神経 / CaMキナーゼ / プロテインホスファターゼ / cDNAクローニング / 蛋白質燐酸化反応 / CaMキナーゼカスケード / 蛋白質脱燐酸化酵素 / 酵素活性の調節機構 / 多機能性蛋白質燐酸化酵素 / 中枢神経機能 / カルモデュリン依存性蛋白質燐酸化酵素II / CaMKP / ホスファターゼ抵抗性 / Dlx5 / autophosphorylation / λ protein phosphatase / CaMKIα / CaMKIδ / CaMKI / CaMKK / phosphatase / Dlx1 / zebrafish / phosphorylation / Calmodulin Dependent Protein Kinase II / Phospholipid / Catecholamine / Tryptophan Hydroxylase / 自己リン酸化反応 / カルモデュリン依存性蛋白質リン酸化酵素II / セロトニン / リン脂質 / カテコールアミン / トリプトファン水酸化酵素 / dephosphorylation / protein phosphatase / 抗体 / ファーウエスタンブロッティング / 相互作用解析 / 結合タンパク質 / GAPDH / アポトーシス / 胚発生 / ノックダウン / アンチセンスRNA / ゼブラフィッシュ / 脱リン酸化 / CaM-kinase phosphatase N / CaM-kinase phosphatase / CaM kinase kinase / CaM-kinase cascade / 蛋白質脱リン酸化酵素 / 蛋白質リン酸化酵素 / CaMキナーゼI / Aキナーゼ / CaMキナーゼホスファターゼN / CaMキナーゼホスファターゼ / CaMキナーゼキナーゼ / CaMキナーゼII / signal transduction / protein dephosphorylation / protein phosphorylation / synthetic oligopeptide / protein phosp hatase / protein kinase / assay method / Polyacrylamide gel electrophoresis / 蛋白質脱燐酸化反応 / 合成基質ペプチド / アッセイ方法 / ゲル電気泳動法 / Autoinhibitory Domain / CaM-kinase IV Kinase / Calmodulin-dependent Protein Kinase / セカンドメッセンジャー / アイソフォーム / カモルデュリン依存性蛋白質燐酸化酸素IV / カモルデュリン依存性蛋白質燐酸化酸素II / 多機能性蛋白質燐酸化酸素 / 自己阻害ドメイン / カルモデュリンキナーゼIVキナーゼ / カルモデュリンキナーゼIV / カルモデュリンキナーゼII / Nervous System / Calmodulin-dependent protein kinase IV / Calodulin / Calmcium Ion / Calmodulin-dependent Protein Kinase II / 分子生物学 / シエプス後膜主要蛋白質(PSD) / アイソザイム / ATPγS / セカンドメッセンジャ- / 蛋白質燐酸化 / 脳神経疾患 / 発生異常 / カルモジュリン / カルシウム情報伝達系 / 酵素 / インゲルホスファターゼアッセイ / 活性制御 / 基質ターゲッティング / 細胞内局在 / プロテアソーム / プロテインキナーゼ / 酵素学的解析 / 活性断片 / プロセシング / 無細胞タンパク合成 / PPM1E / CaMKP-N / 分子病態学 / 阻害剤 / タンパク質リン酸化反応 / タンパク質リン酸化酵素 / カルシウム / ニュ-ロトランスミッタ- / cDNA変異体 / 酵素発現 Less

Activation mechanism and physiological functions of CaMKI-delta
- Principal Investigator
  
  Sueyoshi Noriyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Kagawa University
Development of a new two-dimensional in-gel phosphatase assay and its application to protein phosphatase researchPrincipal Investigator
- Principal Investigator
  
  Kameshita Isamu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical biology
- Research Institution
  Kagawa University
Application of Multi-PK antibody that detects a wide variety of protein kinasesPrincipal Investigator
- Principal Investigator
  
  KAMESHITA Isamu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kagawa University
Mechanisms for switching off of CaM-kinases and their involvement in regulation of the cellular phosphorylation balance
- Principal Investigator
  
  ATSUHIKO Ishida
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hiroshima University
Production of monoclonal antibody to detect a wide variety of protein kinases and its application to proteome researchPrincipal Investigator
- Principal Investigator
  
  KAMESHITA Isamu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kagawa University
Enzymatic study of CaM kinase phosphatase for elucidation of its biological function
- Principal Investigator
  
  TAKEUCHI Masayuki, 石田敦彦
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Asahikawa Medical College
Studies on Regulatory Mechanisms of CaM-dependent protein kinase phosphatases that dephosphorylate multifunctional CaM-dependent protein kinasesPrincipal Investigator
- Principal Investigator
  
  KAMESHITA isamu
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kagawa University
Signal Transduction Mediated by Multifunctional Ca^<2+>/calmodulin-dependent Protein Kinases
- Principal Investigator
  
  FUJISAWA Hitoshi
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Asahikawa Medical College
カルシウム／カルモデュリン依存性多機能性蛋白質燐酸化酵素を介する情報伝達機構
- Principal Investigator
  
  藤沢仁 (藤澤仁)
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Asahikawa Medical College
Development of methods for detection of various protein kinases in sodium dodecyl sulfate-polyacrylamide gel
- Principal Investigator
  
  FUJISAWA Hitoshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Asahikawa Medical College
カルシウム/カルモデュリン依存性多機能性タンパク質リン酸化酵素の活性制御機構
- Principal Investigator
  
  藤澤仁
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Asahikawa Medical College
Regulation of Multifunctional Calmodulin-dependent Protein Kinase IV by PhosphorylationPrincipal Investigator
- Principal Investigator
  
  KAMESHITA Isamu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Asahikawa Medical College
Regulation of the Function of CNS by Ca^<2+>/calmodulin-dependent Multifunctional Protein Kinases
- Principal Investigator
  
  FUJISAWA Hitoshi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Asahikawa Medical College
トランスミッタ-放出におけるカルモデュリン依存性蛋白質燐酸化酸素IIの役割ー変異酵素を用いた解析ー
- Principal Investigator
  
  藤澤仁
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Asahikawa Medical College
Studies on Protein Kinases in Rat Cerebral Postsynaptic DensityPrincipal Investigator
- Principal Investigator
  
  KAMESHITA Isamu
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Asahikawa Medical College
トランスミッタ-放出におけるカルモデュリン依存性蛋白質燐酸化酵素IIの役割ー変異酵素を用いた解析ー
- Principal Investigator
  
  FUJISAWA Hitoshi
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Asahikawa Medical College
Structure and Function of Calmodulin-dependent Protein Kinase II and Its Physiological Significance
- Principal Investigator
  
  FUJISAWA Hitoshi
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Asahikawa Medical College
Regulatory-Mechanism of Monoamine Biosynthesis in Central Nervous System
- Principal Investigator
  
  FUJISAWA Hitoshi
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Asahikawa Medical College

[Journal Article] Functions and dysfunctions of Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP/PPM1F) and CaMKP-N/PPM1E2018
- Author(s)
  Ishida A, Sueyoshi N, Kameshita I
- Journal Title
  
  Arch Biochem Biophys.
  
  Volume: 640 Pages: 83-92
- DOI
  10.1016/j.abb.2018.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01824, KAKENHI-PROJECT-15K07842, KAKENHI-PROJECT-18K05357
[Journal Article] Facile preparation of highly active casein kinase 1 using Escherichia coli constitutively expressing lambda phosphatase2018
- Author(s)
  Akizuki Kazutoshi、Toyama Taku、Yamashita Masashi、Sugiyama Yasunori、Ishida Atsuhiko、Kameshita Isamu、Sueyoshi Noriyuki
- Journal Title
  
  Analytical Biochemistry
  
  Volume: 549 Pages: 99-106
- DOI
  10.1016/j.ab.2018.03.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17J09227, KAKENHI-PROJECT-15K01824, KAKENHI-PROJECT-15K07842, KAKENHI-PROJECT-18K05357, KAKENHI-PROJECT-18K06134
[Journal Article] Characterization of CoPK02, a Ca2+/calmodulin-dependent protein kinase in mushroom Coprinopsis cinerea.2018
- Author(s)
  Yamashita M, Sueyoshi N, Yamada H, Katayama S, Senga Y, Takenaka Y, Ishida A, Kameshita I, Shigeri Y
- Journal Title
  
  Biosci Biotechnol Biochem.
  
  Volume: in press Issue: 8 Pages: 1335-1343
- DOI
  10.1080/09168451.2018.1462692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01824, KAKENHI-PROJECT-15K07842, KAKENHI-PROJECT-18K05357
[Journal Article] Subcellular distribution of cyclin-dependent kinase-like 5 (CDKL5) is regulated through phosphorylation by dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A)2017
- Author(s)
  Ami Oi, Syouichi Katayama, Naoya Hatano, Yasunori Sugiyama, Isamu Kameshita, Noriyuki Sueyoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 482 Issue: 2 Pages: 239-245
- DOI
  10.1016/j.bbrc.2016.11.048
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26750372, KAKENHI-PROJECT-15K07842
[Journal Article] Expression analyses of splice variants of zebrafish cyclin-dependent kinase-like 5 and its substrate, amphiphysin 12016
- Author(s)
  Syouichi Katayama, Yukako Senga, Ami Oi, Yosuke Miki, Yasunori Sugiyama, Noriyuki Sueyoshi, Isamu Kameshita
- Journal Title
  
  Gene
  
  Volume: 583 Issue: 1 Pages: 15-23
- DOI
  10.1016/j.gene.2016.02.036
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26750372, KAKENHI-PROJECT-14J07002, KAKENHI-PROJECT-25350978, KAKENHI-PROJECT-15K07842
[Journal Article] Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP/PPM1F) interacts with neurofilament L and inhibits its filament association.2016
- Author(s)
  Ozaki H, Katoh T, Nakagawa R, Ishihara Y, Sueyoshi N, Kameshita I, Taniguchi T, Hirano T, Yamazaki T, Ishida A
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 477 Issue: 4 Pages: 820-825
- DOI
  10.1016/j.bbrc.2016.06.141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01824, KAKENHI-PROJECT-15K07842
[Journal Article] High-performance CaMKI: A highly active and stable form of CaMKIδ produced by high-level soluble expression in Escherichia coli.2016
- Author(s)
  Senga Y, Akizuki K, Katayama S, Shigeri Y, Kameshita I, Ishida A, Sueyoshi N
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 475 Issue: 3 Pages: 277-282
- DOI
  10.1016/j.bbrc.2016.05.060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01824, KAKENHI-PROJECT-15K07842
[Journal Article] Phosphorylated TandeMBP: A unique protein substrate for protein phosphatase assay2016
- Author(s)
  Yasunori Sugiyama, Sho Yamashita, Yuuki Uezato, Yukako Senga, Syouichi Katayama, Naoki Goshima, Yasushi Shigeri, Noriyuki Sueyoshi, Isamu Kameshita
- Journal Title
  
  Analytical Biochemistry
  
  Volume: 513 Pages: 47-53
- DOI
  10.1016/j.ab.2016.08.020
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26750372, KAKENHI-PROJECT-15K07842
[Journal Article] Expression and phosphorylation state analysis of intracellular protein kinases using Multi-PK antibody and Phos-tag SDS-PAGE2015
- Author(s)
  Sugiyama, Y., Katayama, S., Kameshita, I., Morisawa, K. Higuchi, T., Todaka, J., Kinoshita, E., Kinoshita-Kikuta, E., Koike, T., Taniguchi, T., Sakamoto, S.
- Journal Title
  
  MethodsX
  
  Volume: 2 Pages: 469-474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25350978
[Journal Article] Cell-based inhibitor screening identifies multiple protein kinases important for circadian clock oscillations2015
- Author(s)
  Naohiro Kon, Yasunori Sugiyama, Hikari Yoshitane, Isamu Kameshita, Yoshitaka Fukada
- Journal Title
  
  Communicative & Integrative Biology
  
  Volume: 8 Issue: 4 Pages: 1-4
- DOI
  10.4161/19420889.2014.982405
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26750372, KAKENHI-PUBLICLY-15H01395, KAKENHI-PROJECT-25350978, KAKENHI-PROJECT-25440041, KAKENHI-PROJECT-24227001
[Journal Article] The phosphatase-resistant isoform of CaMKI, Ca2+/calmodulin-dependent protein kinase Iδ (CaMKIδ), remains in its 'Primed' form without Ca2+-stimulation.2015
- Author(s)
  Senga Y, Ishida A, Shigeri Y, Kameshita I, Sueyoshi N.
- Journal Title
  
  Biochemistry
  
  Volume: 54 Issue: 23 Pages: 3617-3630
- DOI
  10.1021/bi5012139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01824, KAKENHI-PROJECT-15K07842, KAKENHI-PROJECT-25350978
[Journal Article] Regulation of Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP/PPM1F) by protocadherin-gamma C5 (Pcdh-gamma C5)2015
- Author(s)
  Onouchi T, Kishino-Kaneko Y, Kameshita I, Ishida A, Sueyoshi N.
- Journal Title
  
  Arch Biochem Biophys
  
  Volume: 585 Pages: 109-120
- DOI
  10.1016/j.abb.2015.09.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K01824, KAKENHI-PROJECT-25350978
[Journal Article] Critical Determinants of Substrate Recognition by Cyclin-Dependent Kinase-like 5 (CDKL5)2015
- Author(s)
  Syouichi Katayama, Noriyuki Sueyoshi and Isamu Kameshita
- Journal Title
  
  Biochemistry
  
  Volume: in press Issue: 19 Pages: 2975-2987
- DOI
  10.1021/bi501308k
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J07002, KAKENHI-PROJECT-25350978
[Journal Article] CaMKII is essential for the cellular clock and coupling between morning and evening behavioral rhythms.2014
- Author(s)
  Kon N, Yoshikawa T, Honma S, Yamagata Y, Yoshitane H, Shimizu K, Sugiyama Y, Hara C, Kameshita I, Honma K, Fukada Y.
- Journal Title
  
  Genes Dev
  
  Volume: 28 Issue: 10 Pages: 1101-1110
- DOI
  10.1101/gad.237511.114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23500478, KAKENHI-PUBLICLY-25117707, KAKENHI-PROJECT-25350978, KAKENHI-PROJECT-25440041, KAKENHI-PROJECT-26460313, KAKENHI-PROJECT-26750372, KAKENHI-PROJECT-24390055, KAKENHI-PROJECT-24227001
[Journal Article] Effects of calmodulin on expressionof lignin-modifyingenzymes in Pleurotus ostreatus2014
- Author(s)
  Suetomi, T., Sakamoto, T., Tokunaga, Y., Kameyama, T.,Honda, Y., Kamitsuji, H., Kameshita, I., Izumitsu, K., Suzuki, K., Irie, T.
- Journal Title
  
  Curr. Genet.
  
  Volume: 14 Issue: 2 Pages: 1-14
- DOI
  10.1007/s00294-014-0460-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25350978, KAKENHI-PROJECT-25892024, KAKENHI-PROJECT-15K07517, KAKENHI-PROJECT-15K18655
[Journal Article] Application of two-dimensional electrophoresis using liquid-phase isoelectric focusing2014
- Author(s)
  杉山康憲、片山将一、馬場裕美、末吉紀行、亀下勇
- Journal Title
  
  SEIBUTSU BUTSURI KAGAKU
  
  Volume: 58 Issue: 2 Pages: 56-58
- DOI
  10.2198/sbk.58.56
- NAID
  130004704687
- ISSN
  0031-9082, 1349-9785
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25350978
[Journal Article] TandeMBP: Generation of a unique protein substrate for protein kinase assays.2014
- Author(s)
  (1)Kameshita, I., Yamashita, S., Katayama, S., Senga, Y., Sueyoshi, N.
- Journal Title
  
  J. Biochem.
  
  Volume: 156 Issue: 3 Pages: 147-154
- DOI
  10.1093/jb/mvu025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J09676, KAKENHI-PROJECT-14J07002, KAKENHI-PROJECT-25350978, KAKENHI-PROJECT-25850244
[Journal Article] Nuclear translocation of doublecortin-like protein kinase and phosphorylation of a transcription factor JDP22014
- Author(s)
  T. Nagamine, S. Nomada, T. Onouchi, I. Kameshita, N. Sueyoshi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 446 Issue: 1 Pages: 73-78
- DOI
  10.1016/j.bbrc.2014.02.075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25350978, KAKENHI-PROJECT-25850244
[Journal Article] Cellular localization of CoPK12, a Ca2+/calmodulin-dependent protein kinase in mushroom Coprinopsis cinerea, is regulated by N-myristoylation and limited proteolysis.2014
- Author(s)
  Kaneko K, Tabuchi M, Sueyoshi N, Ishida A, Utsumi T, Kameshita I
- Journal Title
  
  Journal of Biochemistry
  
  Volume: in press Issue: 1 Pages: 51-61
- DOI
  10.1093/jb/mvu018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580136, KAKENHI-PROJECT-25350978, KAKENHI-PROJECT-25850244, KAKENHI-PROJECT-26450125
[Journal Article] In-gel kinase assay revisited2014
- Author(s)
  石田敦彦、亀下勇
- Journal Title
  
  SEIBUTSU BUTSURI KAGAKU
  
  Volume: 58 Issue: 2 Pages: 62-64
- DOI
  10.2198/sbk.58.62
- NAID
  130004704689
- ISSN
  0031-9082, 1349-9785
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25350978
[Journal Article] Expression and gene knockdown of zebrafish Ca/calmodulin-dependent protein kinase I-LL2013
- Author(s)
  Y. Senga, K .Yoshioka, I. Kameshita, N. Sueyoshi
- Journal Title
  
  Arch. Biochem. Biophys.
  
  Volume: 540 Pages: 41-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25350978
[Journal Article] Identification of amphiphysin 1 as an endogenous substrate for CDKL5, a protein kinase associated with X-linked neurodevelopmental disorder.2013
- Author(s)
  Sekiguchi M, Katayama S, Hatano N, Shigeri Y, Sueyoshi N, Kameshita I.
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 535(2) Issue: 2 Pages: 257-267
- DOI
  10.1016/j.abb.2013.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501296, KAKENHI-PROJECT-25350978, KAKENHI-PROJECT-25850244
[Journal Article] Ink-native electrophoresis: An alternative to blue-native electrophoresis more suitable for in-gel detection of enzymatic activity.2013
- Author(s)
  Kaneko K, Sueyoshi N, Kameshita I, Ishida A,
- Journal Title
  
  Anal. Biochem.
  
  Volume: 440 Issue: 2 Pages: 142-144
- DOI
  10.1016/j.ab.2013.05.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25340047, KAKENHI-PROJECT-25350978, KAKENHI-PROJECT-25850244
[Journal Article] An active C-terminally truncated form of Ca2+/calmodulin-dependent protein kinase phosphatase-N (CaMKP-N/PPM1E).2013
- Author(s)
  Ishida A, Tsumura K, Oue M, Takenaka Y, Shigeri Y, Goshima N, Ishihara Y, Hirano T, Baba H, Sueyoshi N, Kameshita I, Yamazaki T.
- Journal Title
  
  BioMed Res. Int.
  
  Volume: 2013 Pages: 134813-134813
- DOI
  10.1155/2013/134813
- NAID
  120006557539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25340047, KAKENHI-PROJECT-25350978, KAKENHI-PROJECT-25460299, KAKENHI-PROJECT-25850244
[Journal Article] Knockdown of two splice variants of Ca^<2+>/ calmodulin-dependent protein kinase Iδcauses developmental abnormalities in zebrafish, Danio rerio2012
- Author(s)
  Senga, Y., Nagamine, T., Kameshita, I., Sueyoshi, N.
- Journal Title
  
  Arch. Biochem. Biophys
  
  Volume: 517 Pages: 71-82
- Data Source
  KAKENHI-PROJECT-21510226
[Journal Article] Functional processing of nuclearCa^<2+>/ calmodulin-dependent protein kinasephosphatase(CaMKP-N): evidence for acritical role of proteolytic processing inthe regulation of its catalytic activitysubcellular localization and substratetargeting in vivo2012
- Author(s)
  Sueyoshi N., NimuraT., OnouchiT., BabaH., TakenakaS., Ishida, A. Kameshita, I.
- Journal Title
  
  Arch. Biochem. Biophys
  
  Volume: 517 Pages: 43-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590334
[Journal Article] Calcium/ calmodulin-dependent protein kinase IV involvement in the pathophysiology of glucotoxicity in rat pancreatic beta-cells2011
- Author(s)
  Sugiyama, Y., Murao, K., Imachi, H., Sueyoshi, N., Ishida, T., Kameshita, I.
- Journal Title
  
  Metabolism
  
  Volume: 60 Pages: 145-153
- Data Source
  KAKENHI-PROJECT-21510226
[Journal Article] In-Gel Protein Phosphatase Assays and Other Useful Methods for the Detection of Protein Phosphatase Activities2011
- Author(s)
  Ishida, A., Kameshita, I
- Journal Title
  
  Anticancer Agents Med. Chem
  
  Volume: 11 Pages: 47-53
- URL
  http://www.benthamdirect.org/pages/content.php?ACAMC/2011/00000011/00000001/0005W.SGM
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590334
[Journal Article] CoPK32 is a novel stress-responsive protein kinase in the mushroom Coprinopsis cinerea2011
- Author(s)
  Kaneko, K., Sugiyama, Y., Yamada, Y., Sueyoshi, N., Watanabe, A., Asada, Y., Ishida, A., Kameshita, I.
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1810 Pages: 620-629
- Data Source
  KAKENHI-PROJECT-21510226
[Journal Article] Influence of Ser/ Pro-rich domain and kinase domain of doublecortin-like protein kinase on microtubule-binding activity2011
- Author(s)
  Nagamine, T., Shimomura, S., Sueyoshi, N., Kameshita, I.
- Journal Title
  
  J. Biochem
  
  Volume: 149 Pages: 619-627
- Data Source
  KAKENHI-PROJECT-21510226
[Journal Article] Application of multi-PK antibody that detects a wide variety of protein kinases2011
- Author(s)
  亀下勇、末吉紀行
- Journal Title
  
  生化学
  
  Volume: 83 Pages: 330-335
- NAID
  10029068281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510226
[Journal Article] Detection of protein kinase substrates in tissue extracts after separation by isoelectric focusing2011
- Author(s)
  Senga, Y., Nagamine, T., Sekiguchi, M., Kaneko, K., Sueyoshi, N., Kameshita, I.
- Journal Title
  
  Anal. Biochem
  
  Volume: 408 Pages: 345-347
- Data Source
  KAKENHI-PROJECT-21510226
[Journal Article] A minimum size homologue of Ca^<2+>/ calmodulin-dependent protein kinaseIV naturally occurring in zebrafish2010
- Author(s)
  Nimura, T., Sugiyama, Y., Sueyoshi, N., Shigeri, Y., Ishida, A., Kameshita, I.
- Journal Title
  
  J. Biochem
  
  Volume: 147 Issue: 6 Pages: 857-865
- DOI
  10.1093/jb/mvq021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590334
[Journal Article] Expression and characterization of PKL01, an Ndr kinase homolog in Lotus japonicus2010
- Author(s)
  亀下勇, 他
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 147 Pages: 799-807
- NAID
  10027876295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21510226
[Journal Article] Oxazolone-induced over-expression of focal adhesion kinase in colonic epitherial cells of colitis mouse model2010
- Author(s)
  Ma, Y., Semba, S., Takeuchi, M., Kameshita, I., Ishida, A., Kato, S., Katoh, T., Liu, Y., Taniguchi, T.
- Journal Title
  
  FEBS Lett
  
  Volume: 584 Pages: 3949-3954
- Data Source
  KAKENHI-PROJECT-21510226
[Journal Article] Expression and characterization of PKL01, an Ndr kinase homologue in Lotus japonicus2010
- Author(s)
  Kameshita, I., Shimomura, S., Nishio, K., Sueyoshi, N., Nishida, T., Nomura, M., Tajima, S.
- Journal Title
  
  J. Biochem
  
  Volume: 147 Pages: 799-807
- Data Source
  KAKENHI-PROJECT-21510226
[Journal Article] A minimum size homologue of Ca^<2+>/ calmodulin-dependent protein kinase IV naturally occurring in zebrafish2010
- Author(s)
  Nimura, T., Sugiyama, Y., Sueyoshi, N., Shigeri, Y., Ishida, A., Kameshita, I.
- Journal Title
  
  J. Biochem
  
  Volume: 147 Pages: 857-865
- NAID
  10027876530
- Data Source
  KAKENHI-PROJECT-21510226
[Journal Article] Identification of an endogenous substrate of zebrafish doublecortin-like protein kinase using a highly active truncation mutant2010
- Author(s)
  Shimomura, S., Nagamine, T., Hatano, N., Sueyoshi, N., Kameshita, I.
- Journal Title
  
  J. Biochem
  
  Volume: 147 Pages: 711-722
- NAID
  10027875877
- Data Source
  KAKENHI-PROJECT-21510226
[Journal Article] The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1delta/ epsilon2010
- Author(s)
  Sugiyama, Y., Hatano, N., Sueyoshi, N., Suetake, I., Tajima, S., Kinoshita, E., Kinoshita-Kikuta, E., Koike, T., Kameshita, I.
- Journal Title
  
  Biochem. J
  
  Volume: 427 Pages: 489-497
- Data Source
  KAKENHI-PROJECT-21510226
[Journal Article] Novel Ca^<2+>/ calmodulin-dependent protein kinase expressed in actively growing mycelia of the basidiomycetous mushroom Coprinus cinereus2009
- Author(s)
  Kaneko, K., Yamada, Y., Sueyoshi, N., Watanabe, A., Asada, Y., Kameshita, I.
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1790 Pages: 71-79
- Data Source
  KAKENHI-PROJECT-21510226
[Journal Article] Involvement of Ca2+/calmodulin-dependent protein kinases in mycelial growth of the mushroom, Coprinus cinereus2007
- Author(s)
  亀下勇他
- Journal Title
  
  Biochimica et Biophysica Acta (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17550157
[Journal Article] Involvement of Ca2+/calmodulin-dependent protein kinase in mycelial growth of the basidiomycetous mushroom, Coprinus cinereus2007
- Author(s)
  Kameshita, I.et al.
- Journal Title
  
  Biochim.Biophys.Acta (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17550157
[Journal Article] Expression cloning of a variety of novel protein kinases in Lotus japonicus2005
- Author(s)
  亀下勇他
- Journal Title
  
  Journal of Biochemistry 137巻
  
  Pages: 33-39
- NAID
  10017342482
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17550157
[Journal Article] プロテインキナーゼを網羅的に検出する抗体の作製とその利用2005
- Author(s)
  亀下勇, 茂里康
- Journal Title
  
  バイオサイエンスとインダストリー 63巻
  
  Pages: 13-17
- NAID
  10016144537
- Data Source
  KAKENHI-PROJECT-17550157
[Journal Article] Expression cloning of a variety of novel protein kinase in Lotus japonicus2005
- Author(s)
  亀下勇他
- Journal Title
  
  Journal of Biochemistry 137巻
  
  Pages: 33-39
- NAID
  10017342482
- Data Source
  KAKENHI-PROJECT-17550157
[Journal Article] 多機能性カルモデュリン依存性プロテインキナーゼを制御するプロテインホスファターゼ2005
- Author(s)
  末古紀行, 石田敦彦, 亀下男
- Journal Title
  
  生化学 77巻
  
  Pages: 1317-1326
- Data Source
  KAKENHI-PROJECT-17550157
[Journal Article] Expression cloning of a variety of protein kinases in Lotus japonicus2005
- Author(s)
  Kameshita, I.et al.
- Journal Title
  
  J.Biochem. 137
  
  Pages: 33-39
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17550157
[Journal Article] Generation of a polyclonal antibody that simultaneously detects multiple Ser/Thr protein kinases.2004
- Author(s)
  Kameshita, I.
- Journal Title
  
  J.Biochem.Biophys.Methods. 60
  
  Pages: 13-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570094
[Journal Article] Generation of a polyclonal antibody that simultaneously detects multiple Ser/Thr protein kinases.2004
- Author(s)
  Kameshita, I.
- Journal Title
  
  J. Biochem. Biophys. Methods 60
  
  Pages: 13-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570094
[Journal Article] A new approach for the detection of multiple protein kinases using monoclonal antibodies directed to the highly conserved region of protein kinases.2003
- Author(s)
  Kameshita, I.
- Journal Title
  
  Anal. Biochem. 322
  
  Pages: 215-224
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570094
[Journal Article] A new approach for the detection of multiple protein kinases using monoclonal antibodies directed to the highly conserved region of protein kinases.2003
- Author(s)
  Kameshita, I.
- Journal Title
  
  Anal.Biochem. 322
  
  Pages: 215-224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570094
[Patent] カルモジュリン依存性タンパク質リン酸化酵素Ｉ由来ポリペプチド、リン酸化剤、および製造方法2016
- Inventor(s)
  秋月一駿, 片山将一, 亀下勇、末吉紀行　他3名
- Industrial Property Rights Holder
  秋月一駿, 片山将一, 亀下勇、末吉紀行　他3名
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-095770
- Filing Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-15K07842
[Patent] 抗チロシンキナーゼ抗体及びその利用2012
- Inventor(s)
  杉山康憲、末吉紀行、亀下勇、茂里康、達吉郎、湯元昇、石田敦彦、谷口隆信
- Industrial Property Rights Holder
  香川大学、産業技術総合研究所
- Acquisition Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21510226
[Patent] セリン-トレオニンタンパク質リン酸化酵素を認識するモノクローナル抗体2009
- Inventor(s)
  茂里康、達吉郎、湯元昇、石田敦彦、柘植敏之、岡崎勝一郎、亀下勇
- Industrial Property Rights Holder
  香川大学、産業技術総合研究所
- Acquisition Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-21510226
[Patent] プロテインホスファターゼの特異的阻害剤2007
- Inventor(s)
  亀下勇他
- Industrial Property Rights Holder
  香川大学産総研
- Industrial Property Number
  2007-027997
- Filing Date
  2007-02-17
- Data Source
  KAKENHI-PROJECT-17550157
[Patent] 抗チロシンキナーゼ抗体およびその利用2005
- Inventor(s)
  亀下勇他
- Industrial Property Rights Holder
  香川大学
- Industrial Property Number
  2005-190494
- Filing Date
  2005-06-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17550157
[Patent] 抗チロシンキナーゼ抗体およびその利用2005
- Inventor(s)
  亀下勇他
- Industrial Property Rights Holder
  香川大学, 産総研, 旭川医大
- Industrial Property Number
  2005-190494
- Filing Date
  2005-06-29
- Data Source
  KAKENHI-PROJECT-17550157
[Presentation] ESTABLISHMENT of a NEW ESCHERICHIA COLI STRAIN CONSTITUTIVELY EXPRESSING LAMBDA PHOSPHATASE, and APPLICATION to the PREPARATION of HIGHLY ACTIVE CASEIN KINASE 12018
- Author(s)
  Akizuki, K., Toyama, T., Yamashita, M., Ishida, A., Kameshita, I. Sueyoshi, N.
- Organizer
  2018 IUBMB SEOUL (24th IUBMB Congress & 15th FAOBMB Congress)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] 非リン酸化型プロテインキナーゼの簡易調製法の開発とそれを活用した高活性型CK1の取得2017
- Author(s)
  秋月一駿，山下雅史，遠山拓，石田敦彦，亀下勇，末吉紀行
- Organizer
  第68回日本電気泳動学会総会
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] 担子菌キノコCoprinopsis cinereaに存在するcalmodulin 2 (CcCaM2)は149番目のシステイン残基を介したジスルフィド結合により二量体を形成する2017
- Author(s)
  山田寛樹，小林博子，金子啓祐，山下雅史，亀下勇，末吉紀行
- Organizer
  2017年度生命科学系学会合同年次大会ConBio2017（第40回日本分子生物学会年会、第90回日本生化学会大会）
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] λ phosphataseを恒常的に発現する大腸菌株BL21(DE3)p λ PPを利用した高活性型casein kinase 1の簡便な調製法2017
- Author(s)
  秋月一駿，遠山拓，石田敦彦，亀下勇，末吉紀行
- Organizer
  2017年度生命科学系学会合同年次大会ConBio2017（第40回日本分子生物学会年会、第90回日本生化学会大会）
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] ゼブラフィッシュCa2+/CaM依存性プロテインキナーゼIγ（CaMKIγ）の機能解析2016
- Author(s)
  遠山拓, 千賀由佳子, 秋月一駿, 亀下勇, 末吉紀行
- Organizer
  支部創立15周年記念日本農芸化学会中四国支部第45回講演会（例会）
- Place of Presentation
  香川
- Year and Date
  2016-06-11
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] 恒常的活性型CaMKIδ(1-299)とCaMKIα(1-294)の活性化メカニズムの比較解析2016
- Author(s)
  秋月一駿, 千賀由佳子, 亀下勇, 石田敦彦, 末吉紀行
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A)はCyclin-dependent kinase-like 5 (CDKL5)をリン酸化し、その局在を制御する2016
- Author(s)
  大井愛海, 片山将一, 波多野直哉, 亀下勇, 末吉紀行
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] 担子菌キノコCoprinopsis cinereaに存在する2種類のCalmodulin (CcCaM1とCcCaM2)について2016
- Author(s)
  山田寛樹, 小林博子, 金子啓祐, 山下雅史, 亀下勇, 末吉紀行
- Organizer
  支部創立15周年記念日本農芸化学会中四国支部第45回講演会（例会）
- Place of Presentation
  香川
- Year and Date
  2016-06-11
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] λ Phosphataseを恒常的に発現する大腸菌株BL21(DE3, pλPP)を用いた非リン酸化型プロテインキナーゼの簡便な調製法の開発2016
- Author(s)
  秋月一駿, 山下雅史, 石田敦彦, 亀下勇, 末吉紀行
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] Cyclin-dependent protein kinase-like 5 (CDKL5)の細胞内局在が変化する要因を解析するツールとしての抗体の作製2016
- Author(s)
  志賀はる香, 大井愛海, 片山将一, 亀下勇, 末吉紀行
- Organizer
  支部創立15周年記念日本農芸化学会中四国支部第45回講演会（例会）
- Place of Presentation
  香川
- Year and Date
  2016-06-11
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] Ca2+/calmodulin依存性プロテインキナーゼI (CaMKI)による金属依存性プロテインホスファターゼ1H (PPM1H)のリン酸化2016
- Author(s)
  植田早紀, 樫村明理, 小野内貴士, 成田拓人, 亀下勇, 末吉紀行
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] 金属イオン依存性プロテインホスファターゼ1H (PPM1H)とそのリン酸化部位(Ser-210)を特異的に認識する抗体の作製2016
- Author(s)
  成田拓人, 植田早紀, 小野内貴士, 樫村明理, 亀下勇, 末吉紀行
- Organizer
  支部創立15周年記念日本農芸化学会中四国支部第45回講演会（例会）
- Place of Presentation
  香川
- Year and Date
  2016-06-11
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] CaMKIとCaMKIのホスファターゼ抵抗性に注目した活性調節機構の比較解析2015
- Author(s)
  千賀由佳子、石田敦彦、茂里康、亀下勇、末吉紀行
- Organizer
  第88回日本生化学会・第38回日本分子生物学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] Dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A)によるCyclin-dependent kinase-like 5 (CDKL5) のリン酸化とその意義2015
- Author(s)
  大井愛海、片山将一、三木洋祐、波多野直哉、杉山康憲、末吉紀行、亀下勇
- Organizer
  第88回日本生化学会・第38回日本分子生物学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] 担子菌Coprinopsis cinereaの成長菌糸に存在するCaMキナーゼ（CoPK02）の性質2015
- Author(s)
  山下雅史、片山将一、千賀由佳子、杉山康憲、末吉紀行、亀下勇
- Organizer
  第88回日本生化学会・第38回日本分子生物学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] Ca2+/CaM-dependent protein kinase I（CaMKI）によるDistal-less homeobox 1 (Dlx1)のリン酸化とオステオカルシンの転写制御2015
- Author(s)
  秋月一駿、千賀由佳子、杉山康憲、亀下勇、末吉紀行
- Organizer
  第88回日本生化学会・第38回日本分子生物学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] CaMKIαとCaMKIδのホスファターゼ抵抗性に注目した活性調節機構の比較解析2015
- Author(s)
  千賀　由佳子、石田　敦彦、茂里　康、亀下　勇、末吉　紀行
- Organizer
  第３８回日本分子生物学会年会　第８８回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] マルチPK抗体とPhos-tagを利用した細胞内リン酸化動態の新規解析法2015
- Author(s)
  杉山康憲、亀下勇、坂本修士
- Organizer
  第66回日本電気泳動学会総会
- Place of Presentation
  東京
- Year and Date
  2015-10-19
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] CaMキナーゼホスファターゼはニューロフィラメントLと結合して重合を阻害する2015
- Author(s)
  尾崎華、加藤剛志、中川綾子、石原康宏、末吉紀行、亀下勇、谷口隆信、山崎岳、石田敦彦
- Organizer
  第88回日本生化学会・第38回日本分子生物学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] Amphiphysin 1のCLAP領域はCyclin-dependent kinase-like 5によってリン酸化されるために重要である2015
- Author(s)
  片山将一、大井愛海、三木洋祐、末吉紀行、亀下勇
- Organizer
  第88回日本生化学会・第38回日本分子生物学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] Ca2+/CaM-dependent protein kinase I δ (CaMKIδ) による Distal-less homeobox 1 (Dlx1) のリン酸化を介したosteocalcinの転写制御2015
- Author(s)
  秋月　一駿、千賀由佳子、杉山　康憲、亀下　勇、末吉　紀行
- Organizer
  第３８回日本分子生物学会年会　第８８回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K07842
[Presentation] Rett症候群の発症に関わるCyclin-dependent kinase-like 5（CDKL5）のアミノ酸変異と基質リン酸化活性2015
- Author(s)
  大井愛海、片山将一、杉山康憲、末吉紀行、亀下勇
- Organizer
  第56回日本生化学会　中国・四国支部例会
- Place of Presentation
  松江市
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] 抗がん剤を処理したヒト白血病細胞HL-60の細胞内キナーゼの発現およびリン酸化動態の解析2015
- Author(s)
  杉山康憲、片山将一、亀下勇、森澤啓子、樋口琢磨、戸高寛、木下英司、木下恵美子、小池透、坂本修士
- Organizer
  第88回日本生化学会・第38回日本分子生物学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] カルモジュリン依存性プロテインキナーゼIアイソフォーム（CaMKIαとCaMKIδ）の自己リン酸化に着目した比較解析2015
- Author(s)
  秋月一駿、千賀由佳子、杉山康憲、亀下勇、末吉紀行
- Organizer
  第56回日本生化学会　中国・四国支部例会
- Place of Presentation
  松江市
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] Protocadherin gamma subfamily C5 (Pcdh-C5)によるCaMK phosphatase (CaMKP-N/PPM1E) の分解抑制2015
- Author(s)
  小野内貴士、石田敦彦、亀下勇、末吉紀行
- Organizer
  第88回日本生化学会・第38回日本分子生物学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] Functional Processing of NuclearCa2+/ Calmodulin-dependent Protein KinasePhosphatase(CaMKP-N) International Symposium on CarcinogenicSpiral & 9th International2012
- Author(s)
  Sueyoshi N., NimuraT., OnouchiT., Baba H., Takenaka S., Ishida A., KameshitaI.
- Organizer
  Conference onProtein Phosphatase
- Place of Presentation
  東京都・東京大学
- Year and Date
  2012-02-01
- Data Source
  KAKENHI-PROJECT-21590334
[Presentation] in vitro合成系で調製したヒトCaMキナーゼホスファターゼ-N(PPM1E)の酵素学的性質2012
- Author(s)
  大上恵1、宮本和寛1、竹中康浩2、茂里康2、五島直樹2、末吉紀行3、亀下勇3、山崎岳1、石田敦彦1
- Organizer
  1広島大学大学院総合科学研究科、2産業技術総合研究所、3香川大学農学部応用生物科学科第52回日本生化学会中国・四国支部総会
- Place of Presentation
  広島市・広島大学霞キャンパス
- Year and Date
  2012-05-14
- Data Source
  KAKENHI-PROJECT-21590334
[Presentation] ゼブラフィッシュで探るCa2+/カルモジュリン依存性プロテインキナーゼホスファターゼ(CaMKP/ PPM1F)と核局在型CaMKP(CaMKP. N/ PPM1E)の機能と活性調節機構2012
- Author(s)
  末吉紀行1, 石田敦彦2, 亀下勇
- Organizer
  1香川大学農学部応用生物科学科、2広島大学大学院総合科学研究科第84回日本生化学会大会
- Place of Presentation
  京都市・京都国際会館(招待講演)
- Year and Date
  2012-09-23
- Data Source
  KAKENHI-PROJECT-21590334
[Presentation] 植物NdrキナーゼのTyrリン酸化活性2011
- Author(s)
  片山将一、杉山康憲、末吉紀行、寺地徹、亀下勇
- Organizer
  平成23年度日本農芸化学会西日本支部・中四国支部合同大会
- Place of Presentation
  宮崎
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] 担子菌キノコにおける新規ストレス応答性プロテインキナーゼの機能解析2011
- Author(s)
  金子啓祐、杉山康憲、山田祐介、末吉紀行、渡邊彰、麻田恭彦、石田敦彦、亀下勇
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] マウス脳においてタンパク質レベルと細胞内局在が日内変動するプロテインキナーゼの探索2011
- Author(s)
  杉山康憲、広瀬健太郎、吉種光、亀下勇、深田吉孝
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] Doublecortin-like protein kinase 2の微小管結合とキナーゼ領域の核移行2011
- Author(s)
  永峰賢、末吉紀行、亀下勇
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] マウス全脳の様々な細胞内画分において発現量が日内変動するプロテインキナーゼの探索2011
- Author(s)
  杉山康憲、広瀬健太郎、吉種光、亀下勇、深田吉孝
- Organizer
  第18回日本時間生物学会
- Place of Presentation
  名古屋
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] 核局在型Ca2+/カルモジュリン依存性プロテインキナーゼホスファターゼ(CaMKP-N・PPM1E)の機能的な限定分解2011
- Author(s)
  小野内貴士1、二村貴樹1、馬場裕美1、竹中忍1、石田敦彦2、亀下勇1、末吉紀行1
- Organizer
  香川大学農学部応用生物科学科、2広島大学大学院総合科学研究科第52回日本生化学会中国・四国支部総会
- Place of Presentation
  広島市・広島大学霞キャンパス
- Year and Date
  2011-05-14
- Data Source
  KAKENHI-PROJECT-21590334
[Presentation] Ca^<2+>/ CaM依存性プロテインキナーゼIδ-LL(CaMKIδ-LL)の生化学的諸性質の解析と遺伝子ノックダウン2011
- Author(s)
  千賀由佳子、吉岡慶子、末吉紀行、亀下勇
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] Ca^<2+>/ CaM依存性プロテインキナーゼI(CaMKI)-deltaはゼブラフィッシュの正常な胚発生に重要である2010
- Author(s)
  千賀由佳子、永峰賢、二村貴樹、末吉紀行、亀下勇
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] Detection of protein kinases and phosphatases expressed in mushroom2010
- Author(s)
  亀下勇
- Organizer
  The Biology of Fungi-IMC9
- Place of Presentation
  エジンバラ(英国)
- Year and Date
  2010-08-04
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] マウス脳におけるプロテインキナーゼの発現と細胞内局在の日内変動2010
- Author(s)
  杉山康憲、広瀬健太郎、吉種光、亀下勇、深田吉孝
- Organizer
  第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] 植物Ndrキナーゼの自己チロシンリン酸化活性2010
- Author(s)
  片山将一、杉山康憲、末吉紀行、寺地徹、亀下勇
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] ゼブラフィッシュの初期胚発生におけるCa^<2+>/ CaM依存性プロテインキナーゼI delta(CaMKIdelta)の役割2010
- Author(s)
  千賀由佳子、永峰賢、二村貴樹、末吉紀行、亀下勇
- Organizer
  第51回日本生化学会中国・四国支部例会
- Place of Presentation
  山口
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] 核局在型Ca2+/カルモジュリン依存性プロテインキナーゼホスファターゼ(CaMKP-N)の機能的な限定分解2010
- Author(s)
  小野内貴士1、二村貴樹1、馬場裕美1、竹中忍1、石田敦彦2、亀下勇1、末吉紀行1
- Organizer
  1香川大・農・応用生物科学、2広島大院・総合科学第83回日本生化学会大会
- Place of Presentation
  神戸市・神戸ポートアイランド
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21590334
[Presentation] マウスDNAメチルトランスフェラーゼ1のDNA結合活性はカゼインキナーゼ1によるリン酸化によって制御される2009
- Author(s)
  杉山康憲、関口茉里、末吉紀行、波多野直哉、木下英司、木下恵美子、小池透、末武勲、田嶋正二、亀下勇
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] Doublecortin-line protein kinaseとDoublecortinの微小管結合力の違いはSP領域に起因する2009
- Author(s)
  永峰賢、下村幸子、末吉紀行、亀下勇
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] CaMKIdはゼブラフィッシュの正常な胚発生に不可欠である2009
- Author(s)
  千賀由佳子、永峰賢、二村貴樹、末吉紀行、亀下勇
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] 担子菌キノコに発現する浸透圧応答性プロテインキナーゼの解析2009
- Author(s)
  金子啓祐、杉山康憲、末吉紀行、亀下勇
- Organizer
  第50回日本生化学会中国・四国支部例会
- Place of Presentation
  鳥取
- Year and Date
  2009-05-16
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] ゼブラフィッシュDoublecortin-like protein kinase(zDCLK)の活性型変異体を用いた内在性基質の探索ならびに同定2009
- Author(s)
  下村幸子、永峰賢、波多野直哉、末吉紀行、亀下勇
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21510226
[Presentation] PPMホスファターゼは金属配位部位に隣接するCys残基の酸化還元によって活性制御を受ける
- Author(s)
  馬場裕美、末吉紀行、亀下勇
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] Exploration of an endogenous substrate for DCKL5, a protein kinase associated with X-linked neurodevelopmental disorders
- Author(s)
  katayama, S., Sueyoshi, N., Kameshita, I.
- Organizer
  第15回IUBMB
- Place of Presentation
  台北
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] プロトカドヘリンγC5を介したCaMKホスファターゼの制御メカニズム
- Author(s)
  小野内貴士、亀下勇、末吉紀行
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] 金属依存性プロテインホスファターゼPPM1Bの機能解析
- Author(s)
  樫村明理、渡辺真以、馬場裕美、小野内貴士、亀下勇、末吉紀行
- Organizer
  日本生化学会中四国支部例会
- Place of Presentation
  愛媛
- Year and Date
  2014-06-05 – 2014-06-06
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] 大腸菌発現系を用いた高活性型CaMKP-Nの取得とその利用
- Author(s)
  朝波彰、小野内貴士、馬場裕美、亀下勇、末吉紀行
- Organizer
  日本生化学会本会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] CaMKIdeltaによるDistal-less homeobox 1　を介した骨形成メカニズム
- Author(s)
  千賀由佳子、杉山康憲、亀下勇、末吉紀行
- Organizer
  日本分子生物学会年回
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] カルシウムがなくても潜在的活性化状態にあるホスファターゼ抵抗性CaMKIアイソフォーム
- Author(s)
  千賀由佳子、石田敦彦、茂里康、亀下勇、末吉紀行
- Organizer
  日本生化学会本会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] CDKL5とCaMキナーゼIの新規基質タンパク質
- Author(s)
  亀下勇
- Organizer
  蛋白研セミナー
- Place of Presentation
  大阪大学
- Invited
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] TandeMBP: MBPを超えるプロテインキナーゼ用人工基質の創製
- Author(s)
  山下翔、片山将一、末吉紀行、亀下勇
- Organizer
  日本生化学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] メタル依存性プロテインホスファターゼ（PPM)の酸化的修飾による活性制御
- Author(s)
  馬場裕美、末吉紀行、渡辺真以、樫村明理、茂里康、五島直樹、亀下勇
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] ゼブラフィッシュに存在する２種類のCDKL5のスプライスバリアントの比較解析
- Author(s)
  片山将一、千賀由佳子、大井愛海、三木洋祐、杉山康憲、末吉紀行、亀下勇
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] Pcdhgc5を介したCaMKP-Nの活性化メカニズム
- Author(s)
  小野内貴士、亀下勇、末吉紀行
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] CDKL5によるAmphiphysin1のリン酸化とCDKL5の基質特異性の解析
- Author(s)
  片山将一、関口茉里、三木洋祐、末吉紀行、亀下勇
- Organizer
  日本生化学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] DCLKの核移行に伴うキナーゼ活性の制御メカニズム
- Author(s)
  野間田祥悟、永峰賢、亀下勇、末吉紀行
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] CaMKIδはCaMKIαとのN末端領域のアミノ酸の相違によりホスファターゼ抵抗性を有するようになる
- Author(s)
  千賀由佳子、亀下勇、石田敦彦、末吉紀行
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25350978
[Presentation] Ca2+/カルモジュリン依存性プロテインキナーゼホスファターゼの機能解析
- Author(s)
  小野内貴士、馬場裕美、亀下勇、末吉紀行
- Organizer
  日本生化学会中四国支部例会
- Place of Presentation
  愛媛
- Year and Date
  2014-06-05 – 2014-06-06
- Data Source
  KAKENHI-PROJECT-25350978

1. FUJISAWA Hitoshi (10027039)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
2. ATSUHIKO Ishida (90212886)

# of Collaborated Projects: 10 results

# of Collaborated Products: 22 results
3. KITANI Takako (70101417)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
4. TAKEUCHI Masayuki (40226999)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
5. SUEYOSHI Noriyuki (90346635)

# of Collaborated Projects: 5 results

# of Collaborated Products: 70 results
6. KATOH Tsuyoshi (60194833)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. TOBIMATSU Takamasa (30188768)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TAKESHI Yamazaki (30192397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. TATSUO Nehira (60321692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TAKAO Mukuda (60346335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TANIGUCHI Takanobu (60217130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SHIGERI Yasushi (90357187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMAUCHI Takashi (90041813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SUGIYAMA YASUNORI (10632599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
15. NAKAMURA Tomoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. ISHIHARA Yasuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 波多野直哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 内海俊彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAMESHITA ISAMU 亀下 勇

Kameshita Isamu 亀下 勇

KAMESHITA Isamu 亀下 勇

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Development of a new two-dimensional in-gel phosphatase assay and its application to protein phosphatase researchPrincipal Investigator

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Application of Multi-PK antibody that detects a wide variety of protein kinasesPrincipal Investigator

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Production of monoclonal antibody to detect a wide variety of protein kinases and its application to proteome researchPrincipal Investigator

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Studies on Regulatory Mechanisms of CaM-dependent protein kinase phosphatases that dephosphorylate multifunctional CaM-dependent protein kinasesPrincipal Investigator

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Regulation of Multifunctional Calmodulin-dependent Protein Kinase IV by PhosphorylationPrincipal Investigator

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KAMESHITA ISAMU 亀下勇

Kameshita Isamu 亀下勇

KAMESHITA Isamu 亀下勇