ARAKAWA Tetsuo 荒川哲男

Researcher Number	60145779
Other IDs
Affiliation (based on the past Project Information) *help	2013 – 2018: 大阪市立大学, 大学院医学研究科, 教授 2011 – 2014: 大阪市立大学, 医学(系)研究科(研究院), 教授 2001 – 2005: 大阪市立大学, 大学院・医学研究科, 教授 2000: 大阪市立大学, 医学部, 教授 1995 – 1999: 大阪市立大学, 医学部, 助教授 1992: 3rd Dept. of Internal Medicine,Associate Professor, 医学部, 助教授 1987 – 1991: 大阪市立大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology / Gastroenterology / General internal medicine(including psychosomatic medicine)
Keywords	Principal Investigator アポトーシス / 胃癌細胞 / 遺伝子治療 / 大腸癌細胞 / 細胞内情報伝達 / cell proliferation / サイトカイン / Helicobacter pylori / 細胞増殖 / 炎症性サイトカイン … More / ヘリコバクター・ピロリ / 抗アポトーシス能 / 転移能 / 癌細胞増殖能 / 胃癌細胞下部 / 血管新生 / 増殖能 / 逆流性食道炎 / 噴門部癌 / 早期診断マーカー / 胃液 / エクソソーム / マイクロRNA / 胃癌 / Wound healing / Inflammation / Regeneration therapy / Differentiation / Mesenchymal stem cell / Inflammatory bowel disease / 抗癌剤 / 大腸癌 / Apoptosis signal-regulating kinase / MAP kinase系 / 創傷治癒 / 炎症 / 再生治療 / 分化 / 骨髄間葉系幹細胞 / 炎症性腸疾患 / cytokine / cyclooxygenase / intracellular signal transduction / arachidonic acid cascade / 転写因子 / プロスタグランジン / ODC / 細胞周期 / バレット腺癌 / PPAR / アデノウィルス / AP-1 / MAP kinase / アデノウイルス / COX / アラキドン酸カスケード / neutrophil / epidermal growth factor / interleukin-1beta / inflammatory cytokine / gastric mucosa / cytotoxin / 胃潰瘍 / Halicobacter pylori / 好中球 / 上皮成長因子 / インターロイキン1β / 胃粘膜 / サイトトキシン / Helicobacfer pylori / ヘリコバクターピロリ / ヘリコバクター / 喘息 / 気管支喘息 … More Except Principal Investigator ストレス / カルシウムイオン / 細胞保護作用 / 腸管神経系 / グリア細胞 / 過敏性腸症候群 / 腸管グリア細胞 / 胃潰瘍 / 知覚過敏性 / 腸管神経 / 消化管運動 / Surface epithelial cell / Histamine / Gastrin / Calcium ion / Gastric mucosa / Prostaglandin / PGI_2生合成 / PGE_2生合成 / PGE_2局在 / エタノール傷害 / 外因性PG / Caイオン / PG生合成 / 壁細胞 / PG局在 / ヒスタミン / ガストリン / エタノ-ル傷害 / 胃粘膜被蓋上皮細胞 / 15-hydroxy-PG-dehydrogenase / サイクロオキシゲナ-ゼ / 酵素抗体法 / サイトプロテクション / プロスタグランディン / Moleculurbiology / Extracellular matrix / Growth factor / Gastric ulcer / 分子生物学 / 細胞外マトリックス / 増殖因子 / Microtubules / Cell injury / Cytoprotection / Eicosanoid / Stomach / 免疫組織化学 / カルシウム / プロスタグラシジン / 超微形態学 / エタノ-ル / 胃粘膜細胞 / フリ-ラジカル / ロイコトリエン / プロスタグランジン / インドメサシン / 胃粘膜培養細胞 / 微細管 / フリーラジカル / 細胞傷害 / アラキドン酸カスケード / 胃 / 腸管過敏性 / ストレス環境 / 腸管運動 / 刺激過敏性 / 大腸収縮運動 / 知覚過敏 / 腸管収縮反応 / klotho / 慢性胃炎 / 消化管上皮 / 創傷治癒 / 細胞増殖 / 胃癌 / Helicobacter pylori / 老化 / 炎症 / 胃発がん / TLR9 / 萎縮性胃炎 / ヘリコバクター・ピロリ / Klotho Less

Responses of enteric glial cells and biological molecules of the digestive tracts under the dysfunctional condition in maternally separated rats
- Principal Investigator
  
  Kazunari Tominaga
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Osaka Medical College
  Osaka City University
The analysis of exosomal microRNA in gastric juice as early diagnostic marker for gastric cancerPrincipal Investigator
- Principal Investigator
  
  Arakawa Tetsuo
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Comprehensive analysis for mechanism(s) of visceral hypersensitivity associated with morphological changes in glial cells response to stress during a growth process
- Principal Investigator
  
  TOMINAGA Kazunari
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Association between Helicobacter pylori infection and bronchial asthmaPrincipal Investigator
- Principal Investigator
  
  ARAKAWA Tetsuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
The role of Klotho, anti-aging molecule, in chronic gastritis and gastric carcinogenesis
- Principal Investigator
  
  TANIGAWA Tetsuya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Therapeutic strategy for intractable inflammatory bowel diseases by mesenchymal stem cellsPrincipal Investigator
- Principal Investigator
  
  ARAKAWA Tetsuo
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Molecular analysis for the regulation of gastric cancer cell proliferation regarding with arachidonic acid cascade and reactive oxygen species.Principal Investigator
- Principal Investigator
  
  ARAKAWA Tetsuo
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Role of Helicobacter pylori cytotoxin in the gastric mucosaPrincipal Investigator
- Principal Investigator
  
  ARAKAWA Tetsuo
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Molecularbiological research for gastric ulcer and cancer, Roles of growth factors and extracellular matrix Professor Assoc. Prof.
- Principal Investigator
  
  KOBAYASHI Kenzo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Role of eicosanoids in gastric mucosal protection and damage
- Principal Investigator
  
  KOBAYASHI Kenzo
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University Medical School
Pathological Study for Peptic Ulcer-Role of Prostaglandin
- Principal Investigator
  
  KOBAYASHI Kenzo
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University

All 2016 2015 2014 2013 2012 2011 2006 2004

All Journal Article Presentation Book

[Book] カラー版消化器病学基礎と臨床機能性ディスペプシア2013
- Author(s)
  藤川佳子、富永和作、荒川哲男
- Total Pages
  1541
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-23590924
[Book] 新しい診断と治療のABC77:機能性食道疾患―GERDと機能性食道障害2013
- Author(s)
  藤原靖弘、谷川徹也、山上博一、斯波将次、渡辺憲治、富永和作、渡辺俊雄、荒川哲男
- Total Pages
  215
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-23590924
[Book] 今日の治療指針急性胃炎・急性胃潰瘍2012
- Author(s)
  荒川哲男
- Total Pages
  2064
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Structural changes in gastric glial cells and delayed gastric emptying as responses to early life stress and acute adulthood stress in rats.2016
- Author(s)
  Tominaga K, Fujikawa Y, Tanaka F, Kamata N, Yamagami H, Tanigawa T, Watanabe T, Fujiwara Y, Arakawa T.
- Journal Title
  
  Life Sci
  
  Volume: 148 Pages: 254-259
- DOI
  10.1016/j.lfs.2016.02.025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08926
[Journal Article] Enteric glial cells are associated with stress-induced colonic hyper-contraction in maternally separated rats.2015
- Author(s)
  Fujikawa Y, Tominaga K, Tanaka F, Tanigawa T, Watanabe T, Fujiwara Y, Arakawa T.
- Journal Title
  
  Neurogastroenterol Motil
  
  Volume: 27 Issue: 7 Pages: 1010-1023
- DOI
  10.1111/nmo.12577
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08926
[Journal Article] Role of small intestinal bacterial overgrowth in severe small intestinal damage in chronic non-steroidal anti-inflammatory drug users.2014
- Author(s)
  Muraki M, Fujiwara Y, Machida H, Okazaki H, Sogawa M, Yamagami H, Tanigawa T, Shiba M, Watanabe K, Tominaga K, Watanabe T, Arakawa T.
- Journal Title
  
  Scand J Gastroenterol
  
  Volume: 49 Pages: 267-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Infliximab and/or immunomodulators inhibit immune responses to trivalent influenza vaccination in adults with inflammatory bowel disease.2014
- Author(s)
  Hagihara Y, Ohfuji S, Watanabe K, Yamagami H, Fukushima W, Maeda K, Kamata N, Sogawa M, Shiba M, Tanigawa T, Tominaga K, Watanabe T, Fujiwara Y, Hirota Y, Arakawa
- Journal Title
  
  J Crohns Colitis.
  
  Volume: 8 Issue: 3 Pages: 223-233
- DOI
  10.1016/j.crohns.2013.08.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Anti-tumour necrosis factor agents reduce non-steroidal anti-inflammatory drug-induced small bowel injury in rheumatoid arthritis patients.2014
- Author(s)
  Watanabe T, Tanigawa T, Shiba M, Nadatani Y, Nagami Y, Sugimori S, Yamagami H, Watanabe K, Tominaga K, Fujiwara Y, Koike T, Arakawa T.
- Journal Title
  
  Gut
  
  Volume: 63 Issue: 3 Pages: 409-414
- DOI
  10.1136/gutjnl-2013-304713
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Mesenchymal stem cells administered in the early phase of tumorigenesis inhibit colorectal tumor development in rats2013
- Author(s)
  Katsuno T, Ochi M, Tominaga K, Tanaka F, Sogawa M, Tanigawa T, Yamagami H, Shiba M, Watanabe K, Watanabe T, Fujiwara Y, Arakawa T.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 53 Issue: 3 Pages: 170-175
- DOI
  10.3164/jcbn.13-68
- NAID
  130004466728
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] 胃潰瘍治癒過程におけるアンチエイジング分子Klothoの発現動態と胃潰瘍治癒に及ぼす影響2013
- Author(s)
  谷川徹也, 渡辺俊雄, 灘谷祐二, 大谷恒史, 十河光栄, 山上博一, 斯波将次, 渡辺憲治, 富永和作, 藤原靖弘, 荒川哲男
- Journal Title
  
  潰瘍
  
  Volume: 40 Pages: 64-68
- NAID
  10031177503
- Data Source
  KAKENHI-PROJECT-23590925
[Journal Article] 胃潰瘍治癒過程におけるアンチエイジング分子Klothoの発現動態と胃潰瘍治癒に及ぼす影響2013
- Author(s)
  谷川徹也, 渡辺俊雄, 灘谷祐二, 大谷恒史, 十河光栄, 山上博一, 斯波将次, 渡辺憲治, 富永和作, 藤原靖弘, 荒川哲男
- Journal Title
  
  潰瘍
  
  Volume: 40巻 Pages: 64-68
- NAID
  10031177503
- Data Source
  KAKENHI-PROJECT-23590925
[Journal Article] Rebamipide inhibits indomethacin-induced small intestinal injury : possible involvement of intestinal microbiota modulation by upregulation ofα-defensin 52013
- Author(s)
  Tanigawa T, Watanabe T, Otani K, Nadatani Y, Ohkawa F, Sogawa M, Yamagami H, Shiba M, Watanabe K, Tominaga K, Fujiwara Y, Takeuchi K, Arakawa T
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 704 Issue: 1-3 Pages: 64-9
- DOI
  10.1016/j.ejphar.2013.02.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] High-mobility group box 1 inhibits gastric ulcer healing through Toll-like receptor 4 and receptor for advanced glycation end products.2013
- Author(s)
  Nadatani Y, Watanabe T, Tanigawa T, Ohkawa F, Takeda S, Higashimori A, Sogawa M, Yamagami H, Shiba M, Watanabe K, Tominaga K, Fujiwara Y, Takeuchi K, Arakawa T.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 11 Pages: e80130-e80130
- DOI
  10.1371/journal.pone.0080130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] High mobility group box 1 promotes small intestinal damage induced by nonsteroidal anti-inflammatory drugs through Toll-like receptor 4.2012
- Author(s)
  Nadatani Y, Watanabe T, Tanigawa T, Machida H, Okazaki H, Yamagami H, Watanabe K, Tominaga K, Fujiwara Y, Arakawa T
- Journal Title
  
  Am J Pathol.
  
  Volume: 181 Issue: 1 Pages: 98-110
- DOI
  10.1016/j.ajpath.2012.03.039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Toll-like receptor 9シグナルはHelicobacter pylori誘発胃炎の初期過程において抗炎症効果を有する2012
- Author(s)
  谷川徹也, 大谷恒史, 渡辺俊雄, 灘谷祐二, 岡崎博俊, 町田浩久, 山上博一, 渡辺憲治, 富永和作, 藤原靖弘, 荒川哲男
- Journal Title
  
  消化器と免疫
  
  Volume: 48 Pages: 97-100
- Data Source
  KAKENHI-PROJECT-23590925
[Journal Article] A multicenter study on the prevalence of Eosinophilic Esophagitis and PPI-responsive esophageal eosinophilic infiltration2012
- Author(s)
  Fujiwara Y, Sugawa T, Tanaka F, Tatsuwaki H, Okuyama M, Hayakawa T, Yamamori K, Wada R, Ohtani K, Uno H, Tanigawa T, Watanabe Y, Tominaga K, Watanabe T, Takaishi O, Saeki Y, Nebiki H, Oshitani N, Sato H, Arakawa T
- Journal Title
  
  Intern Med
  
  Volume: 51 Pages: 3235-9
- NAID
  130003308153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Klotho, an Aging Suppressor, and Fibroblast Growth Factor 23 is Involved in Gastric Ulcer Healing2012
- Author(s)
  Tetsuya Tanigawa, Toshio Watanabe, Yuji Nadatani, Koji Otani, Hirohisa Machida, Hirotoshi Okazaki, Hirokazu Yamagami, Kenji Watanabe, Kazunari Tominaga, Yasuhiro Fujiwara, Tetsuo Arakawa
- Journal Title
  
  Gastroenterology
  
  Volume: 142;Supple1
- Data Source
  KAKENHI-PROJECT-23590925
[Journal Article] Activation of the MyD88 signaling pathway inhibits ischemia-reperfusion injury in the small intestine.2012
- Author(s)
  Watanabe T, Kobata A, Tanigawa T, Nadatani Y, Yamagami H, Watanabe K, Tominaga K, Fujiwara Y, Takeuchi K, Arakawa T
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: 303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Small intestinal injury caused by NSAIDs/aspirin: finding new from old.2012
- Author(s)
  Arakawa T, Watanabe T, Tanigawa T, Tominaga K, Otani K, Nadatani Y, Fujiwara Y.
- Journal Title
  
  Curr Med Chem.
  
  Volume: 19 Pages: 77-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Toll-like receptor 9 signaling has anti-inflammatory effects on the early phase of Helicobacter pylori-induced gastritis.2012
- Author(s)
  Otani K, Tanigawa T, Watanabe T, Nadatani Y, Sogawa M, Yamagami H, Shiba M, Watanabe K, Tominaga K, Fujiwara Y, Arakawa T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 426 Issue: 3 Pages: 342-9
- DOI
  10.1016/j.bbrc.2012.08.080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924, KAKENHI-PROJECT-23590925
[Journal Article] Activation of the MyD88 signaling pathway inhibits ischemia-reperfusion injury in the small intestine2012
- Author(s)
  Watanabe T, Kobata A, Tanigawa T, Nadatani Y, Yamagami H, Watanabe K, Tominaga K, Fujiwara Y, Takeuchi K, Arakawa T
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 303 Issue: 3 Pages: G324-G334
- DOI
  10.1152/ajpgi.00075.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Small intestinal injury caused by NSAIDs/aspirin : finding new from old2012
- Author(s)
  Arakawa T, Watanabe T, Tanigawa T, Tominaga K, Otani K, Nadatani Y, Fujiwara Y
- Journal Title
  
  Curr Med Chem
  
  Volume: 19 Issue: 1 Pages: 77-81
- DOI
  10.2174/092986712803414105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Dysregulated upregulation of T-cell immunoglobulin and mucin domain-3 on mucosal T helper 1 cells in patients with Crohn's disease2011
- Author(s)
  Morimoto K, Hosomi S, Yamagami H, Watanabe K, Kamata N, Sogawa M, Machida H, Okazaki H, Tanigawa T, Nagahara H, Noda E, Tominaga K, Watanabe T, Fujiwara Y, Maeda K, Hirakawa K, Arakawa T
- Journal Title
  
  Scand J Gastroenterol
  
  Volume: 46 Issue: 6 Pages: 701-9
- DOI
  10.3109/00365521.2011.568518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Role of Th-2 cytokines in the development of Barrett's esophagus in rats2011
- Author(s)
  Kohata Y, Fujiwara Y, Machida H, Okazaki H, Yamagami H, Tanigawa T, Watanabe K, Watanabe T, Tominaga K, Wei M, Wanibuchi H, Arakawa T
- Journal Title
  
  J Gastroenterol
  
  Volume: 46 Issue: 7 Pages: 883-93
- DOI
  10.1007/s00535-011-0405-y
- NAID
  10029313176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Dysregulated upregulation of T-cell immunoglobulin and mucin domain-3 on mucosal T helper 1 cells in patients with Crohn's disease.2011
- Author(s)
  Morimoto K, Hosomi S, Yamagami H, Watanabe K, Kamata N, Sogawa M, Machida H, Okazaki H, Tanigawa T, Nagahara H, Noda E, Tominaga K, Watanabe T, Fujiwara Y, Maeda K, Hirakawa K, Arakawa T.
- Journal Title
  
  Scand J Gastroenterol
  
  Volume: 46 Pages: 701-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Role of Th-2 cytokines in the development of Barrett's esophagus in rats.2011
- Author(s)
  Kohata Y, Fujiwara Y, Machida H, Okazaki H, Yamagami H, Tanigawa T, Watanabe K, Watanabe T, Tominaga K, Wei M, Wanibuchi H, Arakawa T.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 46 Pages: 883-93
- NAID
  10029313176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Association between left-handedness and gastrointestinal symptoms.2011
- Author(s)
  Fujiwara Y, Kubo M, Kohata Y, Yamagami H, Tanigawa T, Watanabe K, Watanabe T, Tominaga K, Arakawa T.
- Journal Title
  
  Digestion
  
  Volume: 84 Pages: 114-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590924
[Journal Article] Anti-inflammatory function induced by bone marrow-derived mesenchymal stem cells for dextran sulfate sodium-induced colitis in rats.2006
- Author(s)
  Tanaka F, Arakawa T et al.
- Journal Title
  
  Ulcer Res 33, Vol2(in press)
- NAID
  10018262341
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590675
[Journal Article] Anti-inflammatory function induced by bone marrow-derived mesenchymal stem cells for dextran sulfate sodium-induced colitis in rats.2006
- Author(s)
  Tanaka F, Tominaga K, Ochi M, Tanigawa T, Sasaki E, Watanabe T, Fujiwara Y, Oshitani N, Higuchi K, Arakawa T
- Journal Title
  
  Ulcer Res (in press)
  
  Pages: 33-33
- NAID
  10018262341
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590675
[Journal Article] Roles of cyclooxygenase 2 and microsomal prostaglandin E synthase 1 in rat acid reflux oesophagitis.2006
- Author(s)
  Hayakawa T, Arakawa T et al.
- Journal Title
  
  Gut 55(4)
  
  Pages: 450-456
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590675
[Journal Article] Roles of epidermal growth factor and Na+/H+ exchanger-1 in esophageal epithelial defense against acid-induced injury.2006
- Author(s)
  Fujiwara Y, Higuchi K, Takashima T, Hamaguchi M, Hayakawa T, Tominaga K, Watanabe T, Oshitani N, Shimada Y, Arakawa T
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol. 290(4)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590675
[Journal Article] Roles of cyclooxygenase 2 and microsomal prostaglandin E synthase 1 in rat acid reflux oesophagitis.2006
- Author(s)
  Hayakawa T, Fujiwara Y, Hamaguchi M, Sugawa T, Okuyama M, Sasaki E, Watanabe T, Tominaga K, Oshitani N, Higuchi K, Arakawa T
- Journal Title
  
  Gut. 55(4)
  
  Pages: 450-456
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590675
[Journal Article] Roles of epidermal growth factor and Na+/H+ exchanger-1 in esophageal epithelial defense against acid-induced injury.2006
- Author(s)
  Fujiwara Y, Arakawa T et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 290(4)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590675
[Journal Article] Dominant-negative mutant of c-Jun gene transfer : a novel therapeutic strategy for colorectal cancer.2004
- Author(s)
  Suto R, Tominaga K, Mizuguchi H, Sasaki E, Higuchi K, Kim S, Iwao H, Arakawa T
- Journal Title
  
  Gene Ther. 11(2)
  
  Pages: 187-193
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590675
[Journal Article] Monocytechemotacticprotein-1 regulates leukocyte recruitmentduring gastric ulcer recurrence induced by tumor necrosis factor-alpha.2004
- Author(s)
  Watanabe T, Arakawa T et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 287(4)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590675
[Journal Article] Dominant-negative mutant of c-Jun gene transfer: a novel therapeutic strategy for colorectal cancer.2004
- Author(s)
  Suto R, Arakawa T et al.
- Journal Title
  
  Gene Ther 11(2)
  
  Pages: 187-193
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590675
[Journal Article] Monocyte chemotactic protein-1 regulates leukocyte recruitment during gastric ulcer recurrence induced by tumor necrosis factor-alpha.2004
- Author(s)
  Watanabe T, Higuchi K, Hamaguchi M, Shiba M, Tominaga K, Fujiwara Y, Matsumoto T, Arakawa T
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol. 287(4)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590675
[Journal Article] Correlation of MAP kinases with COX-2 induction differs between MKN45 and HT29 cells.2004
- Author(s)
  Tominaga K, Arakawa T et al.
- Journal Title
  
  Aliment Pharmacol Ther 20, Suppl 1
  
  Pages: 143-150
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590675
[Journal Article] Correlation of MAP kinases with COX-2 induction differs between MKN45 and HT29 cells.2004
- Author(s)
  Tominaga K, Higuchi K, Sasaki E, Suto R, Watanabe T, Fujiwara Y, Oshitani N, Matsumoto T, Kim S, Iwao H, Arakawa T
- Journal Title
  
  Aliment Pharmacol Ther. 20 Suppl 1
  
  Pages: 143-150
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590675
[Journal Article] Has Helicobacter pylori eradication for peptic ulcer been overrated?2004
- Author(s)
  Arakawa T et al.
- Journal Title
  
  Intern Med 43(3)
  
  Pages: 179-183
- NAID
  10012708725
- Data Source
  KAKENHI-PROJECT-15590675
[Presentation] コルチコステロン刺激による腸管グリア細胞への影響2015
- Author(s)
  藤川佳子、富永和作、谷川徹也、渡辺俊雄、藤原靖弘、荒川哲男
- Organizer
  合同学術集会2015
- Place of Presentation
  沖縄科学技術大学院大学
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K08926
[Presentation] 幼少期ストレスが成人期の腸管神経システムと大腸運動機能へ与える影響2014
- Author(s)
  藤川佳子、富永和作、谷川徹也、渡辺俊雄、藤原靖弘、荒川哲男
- Organizer
  第42回日本潰瘍学会
- Place of Presentation
  慶應義塾大学　薬学部（東京都、港区）
- Year and Date
  2014-11-01
- Data Source
  KAKENHI-PROJECT-24590950
[Presentation] Anti-inflammatory effect of Toll-like receptor 9 signaling on Helicobacter pylori-induced gastritis2014
- Author(s)
  Tanigawa T, Otani K, Watanabe T, Nadatani Y, Sogawa M, Yamagami H, Shiba M, Watanabe K, Tominaga K, Fujiwara Y, Arakawa T.
- Organizer
  17th Biennial Meeting of Society for Free Radical Research International (SFRRI 2014)
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-23590925
[Presentation] Morphological and functional changes caused by physical stress in enteric glial cellsinduce colonic hyper-contraction via a neuron-glia transmission in maternally separated rats2014
- Author(s)
  Yoshiko Fujikawa, Kazunari Tominaga, Fumio Tanaka, Hirokazu Yamagami, Tetsuya Tanigawa, Masatsugu Shiba, Kenji Watanabe, Toshio Watanabe, Yasuhiro Fujiwara, Tetsuo Arakawa
- Organizer
  DDW2014　oral presentation、Plenary
- Place of Presentation
  Chicago(USA)
- Year and Date
  2014-05-05
- Data Source
  KAKENHI-PROJECT-24590950
[Presentation] 母子分離モデルにおける成人期ストレスによる大腸グリア細胞の形態変化と大腸運動機能2013
- Author(s)
  藤川佳子、富永和作、田中史生、十河光栄、山上博一、谷川徹也、斯波将次、渡辺憲治、渡辺俊雄、藤原靖弘、荒川哲男
- Organizer
  第99回日本消化器病学会総会
- Place of Presentation
  鹿児島、城山観光ホテル、かごしま県民交流センター
- Data Source
  KAKENHI-PROJECT-24590950
[Presentation] 幼少期ストレスによる胃グリア細胞の形態変化2013
- Author(s)
  藤川佳子、富永和作、荒川哲男
- Organizer
  第21回 JDDW
- Place of Presentation
  東京、品川グランドプリンスホテル新高輪
- Data Source
  KAKENHI-PROJECT-24590950
[Presentation] Structural plasticity of colonic glial cells enhanced by acute stress in adulthood was associated with colonic hyper-contraction in maternally separated rats2013
- Author(s)
  Yoshiko Fujikawa, Kazunari Tominaga, Fumio Tanaka, Mitsue Sogawa, Hirokazu Yamagami, Tetsuya Tanigawa, Masatsugu Shiba, Kenji Watanabe, Toshio Watanabe, Yasuhiro Fujiwara, Tetsuo Arakawa
- Organizer
  Digestive Diseases Weeks
- Place of Presentation
  オーランド、Orange County Convention Center in Orlando
- Data Source
  KAKENHI-PROJECT-24590950
[Presentation] 多チャンネル食道インピーダンス-pHモニタリングを用いたPPI抵抗性NERDの分類とbaseline impedanceの関連2013
- Author(s)
  木幡幸恵、藤原靖弘、荒川哲男
- Organizer
  第99回日本消化器病学会総会
- Place of Presentation
  鹿児島
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-23590924
[Presentation] 酸逆流が関連する好酸球性食道炎の臨床的基礎的研究2012
- Author(s)
  藤原靖弘、須川貴史、荒川哲男
- Organizer
  第98回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-23590924
[Presentation] Klotho, an Aging Suppressor, and Fibroblast Growth Factor 23 is Involved in Gastric Ulcer Healing2012
- Author(s)
  Tanigwa T, Watanabe T, Nadatani Y, Otani K, Machida H, Okazaki H, Yamagami H, Watanabe K, Tominaga K, Fujiwara Y, Arakawa T.
- Organizer
  AGA
- Place of Presentation
  アメリカ合衆国カリフォルニア州サンディエゴ、San Diego Convention Center
- Data Source
  KAKENHI-PROJECT-23590924
[Presentation] Klotho, an aging suppressor, and fibroblast growth factor 23 is involved in gastric ulcer healing2012
- Author(s)
  Tetsuya Tanigawa, Toshio Watanabe, Yuji Nadatani, Koji Otani, Hirohisa Machida, Hirotoshi Okazaki, Hirokazu Yamagami, Kenji Watanabe, Kazunari Tominaga, Yasuhiro Fujiwara, Tetsuo Arakawa
- Organizer
  DDW 2012
- Place of Presentation
  San Diego Convention Center　(San Diego, United States of America)
- Data Source
  KAKENHI-PROJECT-23590925
[Presentation] 母子分離モデルにおける急性ストレス負荷に対する大腸グリア細胞の動態と大腸運動機能への影響2012
- Author(s)
  藤川佳子、富永和作、田中史生、十河光栄、山上博一、谷川徹也、斯波将次、渡辺憲治、渡辺俊雄、藤原靖弘、荒川哲男
- Organizer
  第14回日本神経消化器病学会
- Place of Presentation
  大阪、シェラトン都ホテル
- Data Source
  KAKENHI-PROJECT-24590950
[Presentation] 胃潰瘍治癒過程におけるアンチエイジング分子Klothoの発現動態と潰瘍治癒に及ぼす影響2012
- Author(s)
  谷川　徹也、渡辺　俊雄、灘谷　祐二、大谷　恒史、十河　光栄、山上　博一、斯波　将次、渡辺　憲治、富永　和作、藤原　靖弘、荒川　哲男
- Organizer
  日本潰瘍学会学術集会
- Place of Presentation
  京王プラザ新宿（東京）
- Data Source
  KAKENHI-PROJECT-23590925
[Presentation] Toll-Like Receptor 9 Signaling Has Anti-Inflammatory Effects on the Early Phase of Helicobacter pylori-Induced Gastritis2011
- Author(s)
  Otani K, Watanabe T, Tanigawa T, Nadatani Y, Machida H, Okazaki H, Yamagami H, Watanabe K, Tominaga K, Fujiwara Y, Arakawa T.
- Organizer
  米国消化器病学会
- Place of Presentation
  シカゴ
- Data Source
  KAKENHI-PROJECT-23590924
[Presentation] High-Mobility Group Box1 Promotes Small Intestinal Damage Induced by Non-Steroidal Antiinflammatory Drugs Through Toll-Like Receptor 42011
- Author(s)
  Nadatani Y, Watanabe T, Tanigawa T, Otani K, MAchida H, Okazaki H, Yamagami H, Watanabe K, Tominaga K, Fujiwara Y, Arakawa T.
- Organizer
  米国消化器病学会
- Place of Presentation
  シカゴ
- Data Source
  KAKENHI-PROJECT-23590924

1. FUJIWARA Yasuhiro (40285292)

# of Collaborated Projects: 8 results

# of Collaborated Products: 44 results
2. WATANABE Toshio (50336773)

# of Collaborated Projects: 7 results

# of Collaborated Products: 42 results
3. TOMINAGA Kazunari (80336768)

# of Collaborated Projects: 7 results

# of Collaborated Products: 45 results
4. TANIGAWA Tetsuya (70423879)

# of Collaborated Projects: 5 results

# of Collaborated Products: 35 results
5. KOBAYASHI Kenzo (70046928)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. HIGUCHI Kazuhide (20218697)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
7. NAKAMURA Hajime (60164323)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MACHIDA Hirohisa (00382078)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 藤川佳子 (60711661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 田中史生 (20623292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OTANI Koji

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

ARAKAWA Tetsuo 荒川 哲男

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Responses of enteric glial cells and biological molecules of the digestive tracts under the dysfunctional condition in maternally separated rats

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The analysis of exosomal microRNA in gastric juice as early diagnostic marker for gastric cancerPrincipal Investigator

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Comprehensive analysis for mechanism(s) of visceral hypersensitivity associated with morphological changes in glial cells response to stress during a growth process

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Association between Helicobacter pylori infection and bronchial asthmaPrincipal Investigator

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The role of Klotho, anti-aging molecule, in chronic gastritis and gastric carcinogenesis

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Therapeutic strategy for intractable inflammatory bowel diseases by mesenchymal stem cellsPrincipal Investigator

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Molecular analysis for the regulation of gastric cancer cell proliferation regarding with arachidonic acid cascade and reactive oxygen species.Principal Investigator

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Role of Helicobacter pylori cytotoxin in the gastric mucosaPrincipal Investigator

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Molecularbiological research for gastric ulcer and cancer, Roles of growth factors and extracellular matrix Professor Assoc. Prof.

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Role of eicosanoids in gastric mucosal protection and damage

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Pathological Study for Peptic Ulcer-Role of Prostaglandin

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[Book] カラー版消化器病学基礎と臨床機能性ディスペプシア2013

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[Book] 新しい診断と治療のABC77:機能性食道疾患―GERDと機能性食道障害2013

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ARAKAWA Tetsuo 荒川哲男