KIHARA Minoru 木原実

… Alternative Names

木原実

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Researcher Number	60177904
External Links
Affiliation (based on the past Project Information) *help	2005: YCU, School of Medicine, Associate Professor, 医学部, 準教授 2005: 横浜市立大学, 医学部医学研究科, 準教授 2002 – 2004: 横浜市立大学, 医学部, 講師 2001: 横浜市立大学, 医学部, 助手 1998: 横浜市立大学, 附属病院, 助手 … More 1995 – 1998: 横浜市立大学, 医学部, 助手 1996: 横浜市立大学, 医学部・内科学第二講座, 助手 1986: 横浜市立大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / Metabolomics / Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine / General pharmacology
Keywords	Principal Investigator レニン・アンジオテンシン系 / eNOS / Nephrin / Renin-angiotensin system / Nephropathy / Diabetes / ネフリン / 腎症 / 糖尿病 / ahterosclerosis … More / renin-angiotensin system / caveolin / 血管内皮 / レニンアンジオテンシン系 / カベリオン / NOS / 血管平滑筋 / 動脈硬化 / カベオリン / 緻密斑 / COX-2 / ATla受容体 / ノックアウトマウス / アンジオテンシノーゲン / 傍糸球体装置 / 神経型一酸化窒素合成酵素 / レニン / アンジオテンシンII / TGF-β / 誘導型一酸化窒素合成酵素 / メサンギウム細胞 … More Except Principal Investigator アンジオテンシノーゲン / Angiotensinogen / マウス / 遺伝子発現調節 / ジーンターゲッティング / レニン・アンジオテンシン系 / Mice / Tissue renin-angiotensin-system / Kidney / 組織レニン-アンジオテンシン系 / 組織レニン・アンジオテンシン系 / 腎臓 / Neuronal nitric oxide synthase / Regulation of gene expression / Angiotensin receptor / Renin / Gene Targeting / Renin Angiotensin System / レニン・アンジオチンシン系 / 神経型一酸化窒素合成酵素 / アンジオテンシン受容体 / レニン / ジーンターゲティング / アンジオテンシンノーゲン / アミノ酸遊離 / 孤束核 / push-pull灌流 / γ-アミノ酪酸 / 圧受容器反射 / 延髄腹外側 / ラット / angiotensin II / ミオシン軽鎖 / angiotensinII / 分化 / 動脈硬化症 / APJ受容体 / apelin / angiotenshin II / ヘパリン / 血管平滑筋細胞 / 情報伝達系 / 心肥大 / 心筋細胞 Less

血管収縮作用をもつAPJ受容体の機能解析
- Principal Investigator
  
  HASHIMOTO Tatsuo
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University
Pathophysiological analysis for tissue renin-angiotensin-system using Cre-loxP system
- Principal Investigator
  
  UMEMURA Satoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University (YCU)
Regulatory roles of podocyte slit membrane associated molecules in cell polarity in diabetes nephropathyPrincipal Investigator
- Principal Investigator
  
  UMEMURA Satoshi, 木原実
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Yokohama City University
The role of caveolin in pathogenesis of arteriosclerosisPrincipal Investigator
- Principal Investigator
  
  KIHARA Minoru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University
傍糸球体装置のレニン発現調節機構における神経型一酸化窒素合成酵素の役割Principal Investigator
- Principal Investigator
  
  木原実
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Yokohama City University
培養ラットメサンギウム細胞における誘導型-酸化窒素合成酵素の発現調節因子についてPrincipal Investigator
- Principal Investigator
  
  木原実
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Yokohama City University
Molecular biological studies on regulatory systems of the circulation in angiotensinogen gene knockout mice.
- Principal Investigator
  
  UMEMURA Satoshi, 石井當男
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University
心筋の分化・肥大における心アンジオテンシノーゲン,アンジオテンシン受容体の役割
- Principal Investigator
  
  石井當男
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
圧受容器反射の脳内機構に関する研究-γ-アミノ酪酸作動神経の役割について
- Principal Investigator
  
  久保孝夫
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Yokohama City University

All 2006 2005 2004

All Journal Article Book

[Book] ACE inhibitors for protection against hypertensive target-organ damage2004
- Author(s)
  Kihara M, et al.
- Publisher
  Nippon Rinsho
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590704
[Journal Article] Expression of cyclooxygenase-2 in the juxtaglomerular apparatus of angiotensinogen gene-knockout mice.2006
- Author(s)
  Hashimoto T, Kihara M, et al.
- Journal Title
  
  Nephron Physiol. 102
  
  Pages: 1-8
- Data Source
  KAKENHI-PROJECT-16590892
[Journal Article] Expression of endothelial nitric oxide synthase is suppressed in the renal vasculature of angiotensinogen-gene knockout mice.2006
- Author(s)
  Kihara M et al.
- Journal Title
  
  Cell Tissue Res. 323
  
  Pages: 313-320
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590892
[Journal Article] Expression of endothelial nitric oxide synthase is suppressed in the renal vasculature of angiotensinogen-gene knockout mice.2006
- Author(s)
  Kihara M, et al.
- Journal Title
  
  Cell Tissue Res. 323
  
  Pages: 313-320
- Data Source
  KAKENHI-PROJECT-16790425
[Journal Article] Expression of endothelial nitric oxide synthase is suppressed in the renal vasculature of angiotensinogen-gene knockout mice.2006
- Author(s)
  Kihara M, et al.
- Journal Title
  
  Cell Tissue Res. 323
  
  Pages: 313-320
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590704
[Journal Article] Expression of endothelial nitric oxide synthase is suppressed in the renal vasculature of angiotensinogen-gene knockout mice.2006
- Author(s)
  Kihara M, Sato K, Hashimoto T, et al.
- Journal Title
  
  Cell Tissue Res. 323
  
  Pages: 313-320
- Data Source
  KAKENHI-PROJECT-16590892
[Journal Article] 降圧効果を減じる薬物相互作用として何を注意すればよいか2005
- Author(s)
  木原実, 橋本達夫, 梅村敏
- Journal Title
  
  Modern Physician 25・2
  
  Pages: 179-182
- Data Source
  KAKENHI-PROJECT-16790425
[Journal Article] Heparin recovers AT1 receptor and its intracellular signal transduction in cultured vascular smooth muscle cells2005
- Author(s)
  Hashimoto T, Kihara M, et al.
- Journal Title
  
  FEBS letters 579
  
  Pages: 281-284
- Data Source
  KAKENHI-PROJECT-16790425
[Journal Article] 降圧効果を減じる薬物相互作用として何を注意すればよいか2005
- Author(s)
  木原実, 橋本達夫, 梅村敏
- Journal Title
  
  Modern Physician 25・2
  
  Pages: 179-182
- Data Source
  KAKENHI-PROJECT-16590892
[Journal Article] Heparin recovers AT1 receptor and its intracellular signal transduction in cultured vascular smooth muscle cells.2005
- Author(s)
  Hashimoto T, Kihara M et al.
- Journal Title
  
  FEBS letters 579
  
  Pages: 281-284
- Data Source
  KAKENHI-PROJECT-16590892
[Journal Article] Heparin recovers AT1 receptor and its intracellular signal transduction in cultured vascular smooth muscle cells2005
- Author(s)
  Hashimoto T, Kihara M, et al.
- Journal Title
  
  FEBS Lett. 579
  
  Pages: 281-284
- Data Source
  KAKENHI-PROJECT-16590704
[Journal Article] Alterations in renal endothelial nitric oxide synthase expression by salt diet in angiotensin type-1a gene knockout mice2004
- Author(s)
  Sato K, Kihara M, et al.
- Journal Title
  
  J Am Soc Nephrol 15
  
  Pages: 1756-1763
- Data Source
  KAKENHI-PROJECT-16590892
[Journal Article] ACE阻害薬2004
- Author(s)
  木原実, 橋本達夫, 梅村敏
- Journal Title
  
  日本臨床 62
  
  Pages: 564-568
- Data Source
  KAKENHI-PROJECT-16590892
[Journal Article] Alterations in renal endothelial nitric oxide synthase expression by salt diet in Angiotensin type-1a receptor gene knockout mice2004
- Author(s)
  Sato K, Kihara M, Hashimoto T, et al.
- Journal Title
  
  J Am Soc Nephrol 15
  
  Pages: 1756-1763
- Data Source
  KAKENHI-PROJECT-16590704
[Journal Article] Alterations in renal endothelial nitric oxide synthase expression by salt diet in Angiotensin type-1a receptor gene knockout mice2004
- Author(s)
  Sato K, Kihara M, Hashimoto T, et al.
- Journal Title
  
  J Am Soc Nephrol 15
  
  Pages: 1756-1763
- Data Source
  KAKENHI-PROJECT-16790425
[Journal Article] ACE inhibitors2004
- Author(s)
  Kihara M, Hashimoto T, Umemura S
- Journal Title
  
  Nippon Rinsho 62
  
  Pages: 564-568
- Data Source
  KAKENHI-PROJECT-16790425

1. UMEMURA Satoshi (00128589)

# of Collaborated Projects: 8 results

# of Collaborated Products: 4 results
2. HASHIMOTO Tatsuo (20363806)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. TAMURA Kouichi (40285143)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TOYA Yoshiyuki (30237143)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 石井當男 (90010363)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TAKAGI Nobuyoshi (10163172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MURAKAMI Kazuo (70110517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ISHIGAMI Tomoaki (50264651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. FUKAMIZU Akiyoshi (60199172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 芦野和博 (50254199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 久保孝夫 (10128598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KIHARA Minoru 木原 実

木原 実

Research Projects

Research Products

Co-Researchers

血管収縮作用をもつAPJ受容体の機能解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathophysiological analysis for tissue renin-angiotensin-system using Cre-loxP system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulatory roles of podocyte slit membrane associated molecules in cell polarity in diabetes nephropathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of caveolin in pathogenesis of arteriosclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

傍糸球体装置のレニン発現調節機構における神経型一酸化窒素合成酵素の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

培養ラットメサンギウム細胞における誘導型-酸化窒素合成酵素の発現調節因子についてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular biological studies on regulatory systems of the circulation in angiotensinogen gene knockout mice.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心筋の分化・肥大における心アンジオテンシノーゲン,アンジオテンシン受容体の役割

Principal Investigator

Project Period (FY)

Research Category

Research Institution

圧受容器反射の脳内機構に関する研究-γ-アミノ酪酸作動神経の役割について

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] ACE inhibitors for protection against hypertensive target-organ damage2004

Author(s)

Publisher

Description

Data Source

[Journal Article] Expression of cyclooxygenase-2 in the juxtaglomerular apparatus of angiotensinogen gene-knockout mice.2006

Author(s)

Journal Title

Data Source

[Journal Article] Expression of endothelial nitric oxide synthase is suppressed in the renal vasculature of angiotensinogen-gene knockout mice.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Expression of endothelial nitric oxide synthase is suppressed in the renal vasculature of angiotensinogen-gene knockout mice.2006

Author(s)

Journal Title

Data Source

[Journal Article] Expression of endothelial nitric oxide synthase is suppressed in the renal vasculature of angiotensinogen-gene knockout mice.2006

Author(s)

Journal Title

Description

KIHARA Minoru 木原実

木原実