FUJII Masayuki 藤井政幸

Researcher Number	60199297
Other IDs
Affiliation (based on the past Project Information) *help	2012 – 2015: 近畿大学, 工学部, 教授 2010 – 2012: 近畿大学, 産業理工学部, 教授 2006 – 2008: Kinki University, 産業理工学部, 教授 2004: Kinki University, Department of Environmental and Biological Chemistry, Professor, 産業理工学部, 教授 2003 – 2004: 近畿大学, 九州工学部, 教授 2001: KINKI UNIVERSSITY, KYUSHU SCHOOL OF ENGINEERING, PROFESSOR, 九州工学部, 教授 1999 – 2001: 近畿大学, 九州工学部, 助教授
Review Section/Research Field	Principal Investigator Chemistry related to living body / Bioorganic chemistry / 医薬分子機能学 / Bio-related chemistry Except Principal Investigator Science and Engineering
Keywords	Principal Investigator 28SrRNA / Vero toxin / 治療薬 / 阻害剤 / ベロ毒素 / 遺伝子サイレンシング / therapeutic agents / RNA analogs / RNAデコイ / 28S rRNAアナログ … More / RNAアナログ / inhibitors / Gb3 ceramide / 細胞接着阻害 / 糖鎖受容体 / SPRセンサ / 糖鎖受容体アナログ / Gb3セラミド / 遺伝子デリバリー / アルゴノート２ / 核酸関連化学 / オフターゲット効果 / 核酸医薬 / アルゴノート2 / 化学修飾siRNA / 核酸化学 / ペプチド遺伝子導入剤 / ヌクレアーゼ耐性 / パプチド遺伝子導入剤 / 細胞質局在化 / マルチコンジュゲート / siRNA / 生体機能関連化学 / 医薬化学 / 遺伝子医薬 / ナノバイオ / 合成化学 / 糖化学 / 蛋白質 / 核酸 … More Except Principal Investigator Interaction energy / Molecular sensor / Artificial nuclease / Artificial nucleoside / Molecular crowding / Ribozyme / RNA cleavage / Functional DNA / RNA切断反応 / 最近接塩基対モデル / 金属イオン / 非塩基対部位 / デオキシリボザイム / 熱力学的パラメータ / 二次構造予測 / 核酸高次構造 / 分子認識 / モデル化 / 解析・評価 / 物理化学 / 相互作用エネルギー / 分子センサー / 人工ヌクレアーゼ / 人工ヌクレオチド / 分子クラウディング / リボザイム / RNA切断 / 機能性DNA Less

Exploration of optimized chemical structure of siRNA based on the functional structure of human argonaute 2 proteinPrincipal Investigator
- Principal Investigator
  
  FUJII Masayuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Kinki University
Controlled intracellular delivery of Multi-functional siRNA and gene silencingPrincipal Investigator
- Principal Investigator
  
  FUJII Masayuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kinki University
Control of genetic expression by conjugate siRNA delocalized in cytoplasmPrincipal Investigator
- Principal Investigator
  
  FUJII Masayuki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kinki University
Evaluation of RNA cleavage reaction based on the prediction parameters for nucleic acid structures
- Principal Investigator
  
  SUGIMOTO Naoki
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Konan University
DEVELOPMENT OF THERAPUETIC AGENTS AGAINST VERO TOXIN PRODUCED BY E. COLIPrincipal Investigator
- Principal Investigator
  
  FUJII Masayuki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kinki University
DEVELOPMENT OF RNA ANALOG INHIBITORS AGAINST VERO TOXIN PRODUCED BY E. COLIPrincipal Investigator
- Principal Investigator
  
  FUJII Masayuki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Kinki University

All 2016 2015 2014 2013 2012 2011 2010 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

[Book] 核酸医薬の創製と応用展開第III編 DDS　第6章新規ペプチドによるsiRNAの無毒性細胞導入2016
- Author(s)
  藤井政幸
- Publisher
  ㈱シーエムシー出版
- Data Source
  KAKENHI-PROJECT-25410182
[Book] 遺伝子治療・診断の最先端技術と新しい医薬品・診断薬の開発2014
- Author(s)
  藤井政幸、高科あゆみ、神武洋二郎、森田資隆、山田康枝
- Total Pages
  566
- Publisher
  (株)技術情報協会
- Data Source
  KAKENHI-PROJECT-25410182
[Book] 第4版マクマリー・生物有機化学（共訳）2014
- Author(s)
  藤井政幸　他6名
- Total Pages
  375
- Publisher
  丸善
- Data Source
  KAKENHI-PROJECT-25410182
[Journal Article] 核酸医薬の分子デザイン；化学修飾、コンジュゲート、複合体2016
- Author(s)
  藤井政幸
- Journal Title
  
  Med Chem News
  
  Volume: 26 Pages: 22-28
- NAID
  130007388030
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25410182
[Journal Article] Gene Silencing by Chemically Modified siRNAs Bearing Cationic Charge on 5’-End2015
- Author(s)
  ⑤Yu Ohno, Kanami Akaike, Yasuhiro Shinkai, Hirohumi Fujii, Ayumi Takashina, Jumpei Ariyoshi, Asako Yamayoshi, Akira Murakami and Masayuki Fujii
- Journal Title
  
  Proceedings of the 42nd International Symposium of Nucleic Acid Chemistry
  
  Volume: 2015 Pages: 322-323
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410182
[Journal Article] Gene Silencing by miRNA-like siRNAs Bearing Mismatches and Bulges2015
- Author(s)
  ⑥Yasuhiro Shinkai, Hirohumi Fujii, Yu Ohno, Kanami Akaike, Ayumi Takashina, Jumpei Ariyoshi, Asako Yamayoshi, Akira Murakami and Masayuki Fujii
- Journal Title
  
  Proceedings of the 42nd International Symposium of Nucleic Acid Chemistry
  
  Volume: 2015 Pages: 324-325
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410182
[Journal Article] Bioconjugation of oligodeoxynucleotides carrying 1,4-dicarbonyl groups via reductive amination with lysine residues2015
- Author(s)
  B. Yang, A. Jinnouchi, K. Usui, T. Katayama, M. Fujii, H. Suemune, M. Aso
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 26 Issue: 8 Pages: 1830-1838
- DOI
  10.1021/acs.bioconjchem.5b00361
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26410181, KAKENHI-PROJECT-25410096, KAKENHI-PROJECT-25410182
[Journal Article] Rational Design of siRNA by Chemical Modification and Conjugation2015
- Author(s)
  ③Yasuhiro Shinkai, Yu Ohno, Hirohumi Fujii, Kanami Akaike, Ayumi Takashina, Jumpei Ariyoshi, Asako Yamayoshi, Akira Murakami and Masayuki Fujii
- Journal Title
  
  Proceeding of the 11th Oligonucleotide Therapeutic Society Annual Meeting
  
  Volume: 2015 Pages: 138-138
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410182
[Journal Article] Synthesis, purification and delivery into mammalian cells of phosphoryl guanidine oligonucleotides (PGO) with either DNA or 2'-OMe RNA backbone2015
- Author(s)
  ④Aleksey I. Vladyko, Boris P. Chelobanov, Maxim S. Kupryushkin, Dmitrii V. Pyshnyi, Masayuki Fujii and Dmitry A. Stetsenko
- Journal Title
  
  Proceedings of the 42nd International Symposium of Nucleic Acid Chemistry
  
  Volume: 2015 Pages: 244-245
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410182
[Journal Article] 核酸医薬における生物学的分子基盤と核酸分子設計2015
- Author(s)
  藤井政幸
- Journal Title
  
  日本核酸医薬学会会報
  
  Volume: 19 Pages: 7-7
- Open Access
- Data Source
  KAKENHI-PROJECT-25410182
[Journal Article] Non-Toxic Delivery and Gene Silencing by siRNA-Peptide Complex2013
- Author(s)
  Ayumi Takashina, Jyunichi Obata, Shutaro Fujiaki and Masayuki Fujii
- Journal Title
  
  Peptide Science
  
  Volume: １００ Pages: 92-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25410182
[Journal Article] Conformational changes of the phenyl and naphthyl isocyanate-DNA adducts2013
- Author(s)
  S. Nakano, Y. Uotani, Y. Sato, H. Oka, M. Fujii, and N. Sugimoto
- Journal Title
  
  Nucleic Acids Res.
  
  Volume: 41 Issue: 18 Pages: 8581-8590
- DOI
  10.1093/nar/gkt608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24245033, KAKENHI-PROJECT-24655161, KAKENHI-PROJECT-25410182
[Journal Article] Base-pairing selectivity of a ureido-linked phenyl-2'-deoxycytidine derivative2012
- Author(s)
  Shu-ichi Nakano, Hirohito Oka, Yuuki Uotani, Kazuya Uenishi, Masayuki Fujii and Naoki Sugimoto
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 10 Pages: 9664-9670
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Non-toxic delivery of siRNA by amphiphilic peptides and silencing of hTERT2012
- Author(s)
  Masayuki Fujii and Shutaro Fujiaki
- Journal Title
  
  Journal of Peptide Science
  
  Volume: 18 Pages: 498-499
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Base-pairing selectivity of a ureido-linked phenyl-2’-deoxycytidine derivative2012
- Author(s)
  Masayuki Fujii 他5名
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 10 Issue: 48 Pages: 9664-9670
- DOI
  10.1039/c2ob26897c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Synthesis of and gene silencing by oligonucleotide-peptide conjugates2011
- Author(s)
  Masayuki Fujii
- Journal Title
  
  Peptide Science
  
  Volume: 2010 Pages: 380-380
- NAID
  10028238249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Specific Inhibition of Human Telomerase Activity by siRNA and Phosphorothioate Oligonucleotide-Peptide Conjugates2011
- Author(s)
  Masayuki Fujii, Irmina Diala
- Journal Title
  
  Peptide Science
  
  Volume: 2010 Pages: 383-383
- NAID
  10028238270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Synthesis, Delivery and Gene Silencing of siRNA-NES Conjugates2011
- Author(s)
  Masayuki Fujii and Irmina Diala
- Journal Title
  
  Progress in Drug Delivery Systems
  
  Volume: 10 Pages: 91-96
- NAID
  120005737503
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Use of Nucleic Acid Analogs for the Study of Nucleic Acid Interactions2011
- Author(s)
  Shu Ichi Nakano, Masayuki Fujii and Naoki Sugimoto
- Journal Title
  
  Journal of Nucleic Acids
  
  Volume: 2011 Pages: 1-11
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Highly Enhanced Silencing of bcr/abl Gene by siRNA-NES Peptide Conjugates2011
- Author(s)
  Masayuki Fujii, Yuichi Akagi
- Journal Title
  
  Peptide Science
  
  Volume: 2010 Pages: 379-379
- NAID
  10028238243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Controlled Intracellular Delivery and Antisense Inhibition of DNA-Peptide Conjugates2011
- Author(s)
  Masayuki Fujii, Irmina Diala
- Journal Title
  
  Peptide Science
  
  Volume: 2010 Pages: 382-382
- NAID
  10028238267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Synthesis, Delivery and Gene Silencing of sIRNA-NES Conjugates2011
- Author(s)
  Masayuki Fujii, Irmina Diala
- Journal Title
  
  Progress in Drug Delivery Systems
  
  Volume: 10 Pages: 91-96
- NAID
  120005737503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Synthesis of oligonucleotide-peptide conjugates by solid phase fragment condensation2011
- Author(s)
  Masayuki Fujii, Irmina Diala, 他2名
- Journal Title
  
  Peptide Science
  
  Volume: 2010 Pages: 381-381
- NAID
  10028238260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Specific Suppression of bcr/abl mRNA by Chemically Modified siRNAs Targeting b3a2 Transcripts2010
- Author(s)
  Masayuki Fujii, Irmina Diala, Kazuya Uenishi, Shu-ichi Nakano3 and Naoki Sugimoto
- Journal Title
  
  Nucleosides, Nucleotides and Nucleic Acids
  
  Volume: 29 Pages: 548-549
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Synthesis of siRNA-Peptide Conjugates by Solid Phase Fragment Condensation2010
- Author(s)
  Masayuki Fujii and Irmina Diala
- Journal Title
  
  Nucleosides, Nucleotides and Nucleic Acids
  
  Volume: 29 Pages: 546-547
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Stacking interaction in the middle and at the end of a DNA helix studied with non-natural nucleotides2010
- Author(s)
  Shu-ichi Nakano, Hirohito Oka, Yuuki Uotani, Kazuya Uenishi, Masayuki Fujii and Naoki Sugimoto
- Journal Title
  
  Molecular BioSystems
  
  Volume: 6 Pages: 2023-2029
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Suppression of Telomerase Activity and Proliferation of Cancer Cell Lines by siRNA Targeting hTERT mRNA2010
- Author(s)
  Masayuki Fujii and Irmina Diala
- Journal Title
  
  Nucleosides, Nucleotides and Nucleic Acids
  
  Volume: 29 Pages: 542-543
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Highly Enhanced Silencing Effect by siRNA-Nuclear Export Signal Peptide Conjugates2010
- Author(s)
  Masayuki Fujii and Irmina Diala
- Journal Title
  
  Nucleosides, Nucleotides and Nucleic Acids
  
  Volume: 29 Pages: 544-545
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Highly Enhanced Silencing Effect by siRNA-Nuclear Eeport Signal Peptide Conjugates2010
- Author(s)
  Masayuki Fujii, Irmina Diala
- Journal Title
  
  Nucleosides, Nucleotides and Nucleic Acids
  
  Volume: 29 Pages: 544-545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22550159
[Journal Article] Suppression of bcr-abl mRNA by Chemically Modified siRNA2008
- Author(s)
  Satoshi Murao, Irmma Diala, Masayuki Fujii
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 499-500
- Data Source
  KAKENHI-PROJECT-18550158
[Journal Article] Antisense Inhibition of Human Telomerase by Pho sphorothioate Oligonucleotide-Peptide Conjugates2008
- Author(s)
  Irmma Diala, Satoshi Murao, Masayuki Fujii
- Journal Title
  
  Nucleic Acids Symp. Ser. 52
  
  Pages: 679-680
- Data Source
  KAKENHI-PROJECT-18550158
[Journal Article] Synthesis of Phosphorothioate Oligonucleotide-Peptide Conjugates by Solid Phase Fragment Condensation2007
- Author(s)
  Irmina Diala, Akira Osada, Shmji Maruoka, Takashi Imanisi, Satoshi Murao, Taishi Ato, Hideki Ohba, Masayuki Fujii
- Journal Title
  
  Bioorg. & Med. Chem. Lett. 17(23)
  
  Pages: 6576-6578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18550158
[Journal Article] Functionalization of DNA by the base pair-mimic nucleosides2007
- Author(s)
  Hirohito Oka, Shu-ichi Nakano, Yuuki Uotani, Kazuya Uenishi, Masayuki Fujii, Naoki Sugimoto
- Journal Title
  
  Nucleic Acids Symp. Ser. 51
  
  Pages: 151-152
- Data Source
  KAKENHI-PROJECT-18550158
[Journal Article] Recognition of the base pair-mimic nucleosides by DNA polymerase2006
- Author(s)
  Shu-ichi Nakano, Yuuki Uotani, YTuichi Sato, Hirohito Oka, Kazuya Uenishi, Masayuki Fujii, Naoki Sugimoto
- Journal Title
  
  Nucleic Acids Symp. Ser. 50
  
  Pages: 201-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18550158
[Journal Article] Site-selective RNA cleavage by DNA bearing a base pair-mimic nucleoside.2005
- Author(s)
  S.Nakano, Y.Uotani, K.Uenishi, M.Fujii, N.Sugimoto
- Journal Title
  
  J.Am.Chem. Soc. 127
  
  Pages: 518-519
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13132208
[Patent] 細胞への核酸導入方法、核酸キャリア及び核酸複合体2013
- Inventor(s)
  藤井政幸
- Industrial Property Rights Holder
  藤井政幸
- Industrial Property Rights Type
  特許
- Filing Date
  2013-01-09
- Overseas
- Data Source
  KAKENHI-PROJECT-22550159
[Patent] 細胞への核酸導入方法、核酸キャリア及び核酸複合体2011
- Inventor(s)
  藤井政幸
- Industrial Property Rights Holder
  (財)北九州産業学術推進機構
- Filing Date
  2011-07-07
- Overseas
- Data Source
  KAKENHI-PROJECT-22550159
[Patent] 細胞への核酸導入方法、核酸キャリア及び核酸複合体2011
- Inventor(s)
  藤井政幸
- Industrial Property Rights Holder
  (財)北九州産業学術推進機構
- Filing Date
  2011-07-07
- Overseas
- Data Source
  KAKENHI-PROJECT-22550159
[Patent] 細胞への核酸導入方法、核酸キャリアおよび核酸複合体2010
- Inventor(s)
  藤井政幸
- Industrial Property Rights Holder
  財団法人北九州産業学術推進機構
- Industrial Property Number
  2010-157367
- Filing Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Gene Silencing by Chemically Modified siRNAs Bearing Cationic Charge on 5’-End2015
- Author(s)
  Yu Ohno, Kanami Akaike, Yasuhiro Shinkai, Hirohumi Fujii, Ayumi Takashina, Jumpei Ariyoshi, Asako Yamayoshi, Akira Murakami and Masayuki Fujii
- Organizer
  第42回国際核酸化学シンポジウム
- Place of Presentation
  イーグルひめじあいめっせホール(姫路市)
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] Gene Silencing by miRNA-like siRNAs Bearing Mismatches and Bulges2015
- Author(s)
  ②Yasuhiro Shinkai, Hirohumi Fujii, Yu Ohno, Kanami Akaike, Ayumi Takashina, Jumpei Ariyoshi, Asako Yamayoshi, Akira Murakami and Masayuki Fujii
- Organizer
  第42回国際核酸化学シンポジウム
- Place of Presentation
  イーグルひめじあいめっせホール(姫路市)
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] 5’-アミノTを有するsiRNAの遺伝子サイレンシング効果2015
- Author(s)
  ④大野結有、新貝恭広、藤井啓史、柏原慎一、苗村円佳、神武洋二郎、山吉麻子、村上章、藤井政幸
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都テルサ(京都市)
- Year and Date
  2015-11-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] ミスマッチまたはバルジ構造を有するmiRNA様siRNAの遺伝子サイレンシング効果2015
- Author(s)
  ⑤新貝恭広、藤井啓史、柏原慎一、苗村円佳、神武洋二郎、山吉麻子、村上章、藤井政幸
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都テルサ(京都市)
- Year and Date
  2015-11-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] Rational Design of siRNA by Chemical Modification and Conjugation2015
- Author(s)
  ③Yasuhiro Shinkai, Yu Ohno, Hirohumi Fujii, Kanami Akaike, Ayumi Takashina, Jumpei Ariyoshi, Asako Yamayoshi, Akira Murakami and Masayuki Fujii
- Organizer
  11th Oligonucleotide Therapeutic Society Annual Meeting
- Place of Presentation
  オランダ(ライデン市)
- Year and Date
  2015-09-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] 核酸コンジュゲートの新規固相フラグメント縮合法2014
- Author(s)
  江見友裕、鶴岡昂洋、藤井政幸
- Organizer
  第51回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場(福岡県北九州市）
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] 5'-末端修飾siRNAの遺伝子サイレンシング効果2014
- Author(s)
  鶴岡昂洋、萱野光、江見友裕、高科あゆみ、藤井政幸
- Organizer
  第51回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場(福岡県北九州市）
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] カチオン電荷を有するsiRNAのサイレンシング効果2014
- Author(s)
  高科あゆみ、藤井政幸
- Organizer
  第51回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場(福岡県北九州市）
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] 新規ペプチドによるsiRNAの無毒性細胞導入と遺伝子サイレンシング2013
- Author(s)
  藤井政幸、高科あゆみ、小幡淳一、藤明修太郎
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ（京都市）
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] Structure of Human Argonaute2 Protein and Chemically Modified siRNA2013
- Author(s)
  Ayumi Takashina and Masayuki Fujii
- Organizer
  第40回国際核酸化学シンポジウム
- Place of Presentation
  神奈川大学（横浜市）
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] ヒトアルゴノート２タンパクの機能構造と化学修飾siRNAのサイレンシング効果2013
- Author(s)
  高科あゆみ・藤井政幸
- Organizer
  CSJ化学フェスタ2013
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] Non-Toxic Delivery and Gene Silencing by siRNA-Peptide Complex2013
- Author(s)
  Ayumi Takashina, Jyunichi Obata, Shutaro Fujiaki and Masayuki Fujii
- Organizer
  23rd American Peptide Symposium
- Place of Presentation
  ヒルトンワイコロワホテル（アメリカ、ハワイ州、ワイコロワ）
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] Chemical modification of siRNAs and their silencing effects2013
- Author(s)
  Masayuki Fujii and Ayumi Takashina
- Organizer
  9th Annual Meeting of the Oligonucleotide Therapeutics Society
- Place of Presentation
  ロイヤルコンチネンタルホテル（イタリア、ナポリ市）
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] シグナルペプチドコンジュゲートによるsiRNAの細胞内デリバリーと遺伝子サイレンシング2013
- Author(s)
  藤明修太郎・小幡淳一・藤井政幸
- Organizer
  日本化学会第93春期年会
- Place of Presentation
  立命館大学びわこ・くさつキャンパス
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] ペプチドと核酸の機能融合による細胞内デリバリーと遺伝子サイレンシング2012
- Author(s)
  藤明修太郎、藤井政幸
- Organizer
  日本化学会第92回春季年会
- Place of Presentation
  慶応大学日吉キャンパス(横浜市)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 両親媒性ペプチドによるsiRNAの無毒性細胞内デリバリーとhTERTサイレンシング2012
- Author(s)
  藤明修太郎、藤井政幸
- Organizer
  日本化学会第92回春季年会
- Place of Presentation
  慶応大学日吉キャンパス(横浜市)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Non-toxic Delivery and Gene Silencing by siRNA-Hybrid Peptide Complex2012
- Author(s)
  藤井政幸他1名
- Organizer
  8th Annual Meeting of the Oligonucleotide Therapeutics Society
- Place of Presentation
  ボストン
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 新規小ペプチドによるsiRNAの無毒性細胞導入2012
- Author(s)
  藤井政幸、藤明修太郎、小幡淳一
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] NON-TOXIC INTRACELLULAR DELIVERY AND EFFICIENT GENE SILENCING BY FUNCTIONAL FUSION OF SIRNA AND PEPTIDES2012
- Author(s)
  Shutaro Fujiaki and Masayuki Fujii
- Organizer
  XX International Roundtable on Nucleosides Nucleotides and Nucleic Acids
- Place of Presentation
  Montreal
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 核酸とペプチドの機能融合によるbcr/abl遺伝子サイレンシング2012
- Author(s)
  小幡淳一・藤明修太郎・藤井政幸
- Organizer
  2012年日本化学会西日本大会
- Place of Presentation
  佐賀
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 新規ハイブリッドペプチドによるsiRNAの細胞導入と遺伝子サイレンシング2012
- Author(s)
  藤明修太郎・小幡淳一・藤井政幸
- Organizer
  2012年日本化学会西日本大会
- Place of Presentation
  佐賀
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] siRNA-ペプチド複合体による細胞内デリバリーと遺伝子サイレンシング2012
- Author(s)
  藤井政幸他1名
- Organizer
  第30回メディシナルケミストリーシンポジウム
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 新規ハイブリッドペプチドによるsiRNAの細胞導入と遺伝子サイレンシング2012
- Author(s)
  藤井政幸、他2名
- Organizer
  2012年日本化学会西日本大会
- Place of Presentation
  佐賀大学
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 核酸とペプチドの機能融合によるbcr/abl遺伝子サイレンシング2012
- Author(s)
  藤井政幸、他2名
- Organizer
  2012年日本化学会西日本大会
- Place of Presentation
  佐賀大学
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Specific Delivery of siRNA by Amphiphilic Peptide-Signal Peptide Conjugates2012
- Author(s)
  Shutaro Fujiaki, Junichi Obata, Masayuki Fujii
- Organizer
  第39回国際核酸化学シンポジウム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 新規ハイブリッドペプチドによるsiRNAの細胞導入2012
- Author(s)
  藤明修太郎、行武陽介、藤井政幸
- Organizer
  第49回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 核酸とペプチドの機能融合によるbcr/abl遺伝子サイレンシング2012
- Author(s)
  小幡淳一、山岡史典、藤井政幸
- Organizer
  第49回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Specific Delivery of siRNA by Amphiphilic Peptide-Signal Peptide Conjugates2012
- Author(s)
  藤井政幸、他2名
- Organizer
  第39回国際核酸化学シンポジウム
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] ペプチド‐siRNA複合体の無毒性細胞導入と遺伝子サイレンシング2012
- Author(s)
  藤明修太郎,小幡淳一,藤井政幸
- Organizer
  第2回CSJ化学フェスタ
- Place of Presentation
  横浜(慶応大学日吉キャンパス)
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Non-toxic delivery of siRNA by amphiphilic peptides and silencing of hTERT2012
- Author(s)
  Masayuki Fujii and Shutaro Fujiaki
- Organizer
  32nd European Peptide Symposium
- Place of Presentation
  Athen
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 両親媒性ハイブリッドペプチドによるsiRNA特異的無毒性細胞導入2012
- Author(s)
  藤井政幸・藤明修太郎・小幡淳一
- Organizer
  第22回アンチセンスシンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Non-toxic Delivery and Gene Silencing by siRNA-Hybrid Peptide Complex2012
- Author(s)
  Shutaro Fujiaki, Junichi Obata, Masayuki Fujii
- Organizer
  8th Annual Meeting of the Oligonucleotide Therapeutics Society
- Place of Presentation
  Boston, MA.
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] ペプチド‐siRNA複合体の無毒性細胞導入と遺伝子サイレンシング2012
- Author(s)
  藤井政幸、他2名
- Organizer
  第2回CSJ化学フェスタ2012
- Place of Presentation
  慶応大学日吉キャンパス
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] siRNA-ペプチド機能融合によるデリバリー、遺伝子サイレンシング2012
- Author(s)
  藤井政幸
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] NON-TOXIC INTRACELLULAR DELIVERY AND EFFICIENT GENE SILENCING BY FUNCTIONAL FUSION OF SIRNA AND PEPTIDES2012
- Author(s)
  藤井政幸他1名
- Organizer
  XX International Roundtable on Nucleosides Nucleotides and Nucleic Acids
- Place of Presentation
  モントリオール
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Non-toxic delivery of siRNA by amphiphilic peptides and silencing of hTERT2012
- Author(s)
  藤井政幸他1名
- Organizer
  32nd European Peptide Symposium
- Place of Presentation
  アテネ
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 新規両親媒性ペプチドによるsiRNAの無毒性細胞導入とhTERT遺伝子サイレンシング2012
- Author(s)
  池辺貴彦、橋本武志、藤井政幸
- Organizer
  第49回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] siRNA-ペプチド複合体による細胞内デリバリーと遺伝子サイレンシング2012
- Author(s)
  藤井政幸,藤明修太郎,小幡淳一
- Organizer
  第30回メディシナルケミストリーシンポジウム
- Place of Presentation
  タワーホール船堀、東京
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] ペプチドと核酸の機能融合による細胞内デリバリーと遺伝子サイレンシング2012
- Author(s)
  藤明修太郎、藤井政幸
- Organizer
  日本化学会第92回春季年会
- Place of Presentation
  慶応大学日吉キャンパス
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 両親媒性ハイブリッドペプチドによるsiRNA特異的無毒性細胞導入2012
- Author(s)
  藤井政幸、他2名
- Organizer
  第22回アンチセンスDNA/RNA研究会シンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 両親媒性ペプチドによるsiRNAの無毒性細胞内デリバリーとhTERTサイレンシング2012
- Author(s)
  藤明修太郎、藤井政幸
- Organizer
  日本化学会第92回春季年会
- Place of Presentation
  慶応大学日吉キャンパス
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 塩基性両親媒性ペプチドと二重鎖核酸との相互作用2012
- Author(s)
  西川勇輝、増田春菜、松原愛、藤井政幸
- Organizer
  第49回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] siRNA-NESコンジュゲートによるbcr/abl遺伝子発現制御2011
- Author(s)
  藤井政幸, Irmina Diala
- Organizer
  第20回DDSカンファランス
- Place of Presentation
  静岡県コンベンションアーツセンター(静岡市)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Specific Delivery of siRNA by Hybrid Peptides and Silencing of hTERT2011
- Author(s)
  Masayuki Fujii, Diala Irmina
- Organizer
  第38回核酸化学シンポジウム
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2011-11-09
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] siRNA-NESコンジュゲートの合成、デリバリー、遺伝子サイレンシング2011
- Author(s)
  藤井政幸,Irmina Diala
- Organizer
  第20回DDSカンファランス
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Specific Delivery of siRNA by amphiphilic Peptides and Silencing of hTERT2011
- Author(s)
  Masayuki Fujii, Diala Irmina
- Organizer
  11^<th> US-Japan Symposium on Drug Delivery System
- Place of Presentation
  ウエスチンホテル(ハワイマウイ島ラハイナ)
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Synthesis and highly enhanced silencing effect of siRNA-NES conjugates2010
- Author(s)
  Masayuki Fujii, Irmina Diala
- Organizer
  The 37^<th> International Symposium on Nucleic Acids Chemistry 2010
- Place of Presentation
  横浜、はまぎんホール
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] SUPPRESSION OF TELOMERASE ACTIVITY AND PROLIFERATION OF CANCER CELL LINES BY siRNA TARGETING hTERT mRNA2010
- Author(s)
  Masayuki Fujii, Irmina Diala
- Organizer
  XIX International Round Table "Nucleosides, Nucleotides and Nucleic Acids"
- Place of Presentation
  フランス、リヨン大学
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] SYNTHESIS OF siRNA-PEPTIDE CONJUGATES BY SOLID PHASE FRAGMENT CONDENSATION2010
- Author(s)
  Masayuki Fujii, Irmina Diala
- Organizer
  XIX International Round Table "Nucleosides, Nucleotides and Nucleic Acids"
- Place of Presentation
  フランス、リヨン大学
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Synthesis of Oligonucleotide-Peptide Conjugates by Solid Phase Fragment Condensation2010
- Author(s)
  Masayuki Fujii, Irmina Diala, 他2名
- Organizer
  The 5^<th> International Peptide Symposium
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] HIGHLY ENHANCED SILENCING EFFECT BY siRNA-NUCLEAR EXPORT SIGNAL PEPTIDE CONJUGATES2010
- Author(s)
  Masayuki Fujii, Irmina Diala
- Organizer
  XIX International Round Table "Nucleosides, Nucleotides and Nucleic Acids"
- Place of Presentation
  フランス、リヨン大学
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 酵素的固相ペプチド合成法の開発(3)リパーゼによる固相担体からの切り出しにおけるマイクロ波照射の効果2010
- Author(s)
  三浦航, 赤城雄一, 片岡翔太, 寺田佳毅、藤井政幸
- Organizer
  第47回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Specific Inhibition of Human Telomerase Activity by siRNA and Phosphorothioate Oligonucleotide-Peptide Conjugates2010
- Author(s)
  Masayuki Fujii, Irmina Diala
- Organizer
  The 5^<th> International Peptide Symposium
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 酵素的固相ペプチド合成法の開発(2)イオン性液体中でのリパーゼによる固相担体からの切り出し2010
- Author(s)
  西條清伸、赤城雄一、中野健一、藤井政幸
- Organizer
  第47回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] SPECIFIC SUPPRESSION OF BCR-ABL mRNA BY CHEMICALLY MODIFIED siRNAs TARGETING b3a2 TRANSCRIPTS2010
- Author(s)
  Masayuki Fujii, Irmina Diala
- Organizer
  XIX International Round Table "Nucleosides, Nucleotides and Nucleic Acids"
- Place of Presentation
  フランス、リヨン大学
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] siRNA-NESペフチドコンジュゲートの合成、デリバリー、サイレンシング効果2010
- Author(s)
  赤城雄一、Irmina Diala、藤井政幸
- Organizer
  第20回アンチセンスシンポジウム
- Place of Presentation
  神戸、甲南大学
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Highly Enhanced Silencing of bcr/abl Gene by siRNA-NES Peptide Conjugates2010
- Author(s)
  Yuichi Akagi, Masayuki Fujii
- Organizer
  The 5^<th> International Peptide Symposium
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 酵素的固相ペプチド合成法の開発(1)リパーゼによる固相担体からの切り出し2010
- Author(s)
  赤城雄一、利光貴紀、松本一真、藤井政幸
- Organizer
  第47回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] SYNTHESIS AND HIGHLY ENHANCED SILENSING EFFECT OF siRNA-NES PEPTIDE CONJUGATES2010
- Author(s)
  Masayuki Fujii, Irmina Diala
- Organizer
  The 6^<th> Annual Meeting of the Oligonucleotide Therapeutic Society
- Place of Presentation
  カリフォルニア、ダナポイント
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Synthesis of and gene silencing by oligonucleotide-peptide conjugates2010
- Author(s)
  Masayuki Fujii
- Organizer
  The 5^<th> International Peptide Symposium
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] Controlled Intracellular Delivery and Antisense Inhibition of DNA-Peotide Coniueates2010
- Author(s)
  Masayuki Fujii, Irmina Diala
- Organizer
  The 5^<th> International Peptide Symposium
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 鎖交換による遺伝子変異検出法2008
- Author(s)
  大上博子, 岡本小百合, 村尾聡, 藤井政幸
- Organizer
  第45回化学関連支部合同九州大会
- Place of Presentation
  北九州
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-18550158
[Presentation] アンチセンスペプチド-DNAコンジュゲートによるテロメラーゼ阻害2008
- Author(s)
  Irmina Diala, 村尾聡, 藤井政幸
- Organizer
  第45回化学関連支部合同九州大会
- Place of Presentation
  北九州
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-18550158
[Presentation] Suppression of bcr/abl mRNA by chemically modified siRNA2008
- Author(s)
  Satoshi Murao, Irmina Diala, Masayuki Fujii
- Organizer
  XVIII International Round Table on Nucleosides, Nucleotides & Nucleic Acids
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-18550158
[Presentation] 細胞内精密デリバリー制御のためのDNA/RNA-ペプチドコンジュゲートの合成2007
- Author(s)
  阿藤高志, 原口正人, 渡辺真理, 松木園美穂, 明日山康夫, 丸岡慎治, 今西高司, 長田聡, Diala Irmina, 村尾聡, 大庭英樹, 藤井政幸
- Organizer
  遺伝子・デリバリー研究会第7回シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-05-18
- Data Source
  KAKENHI-PROJECT-18550158
[Presentation] Synthesis, Controlled Delivery and Antisense Effects of Oligonucleotide-Peptide Conjugates2006
- Author(s)
  Masamichi Shimizu, Keiko Doi, Taishi Ato, Irmina Diala, Masato Haraguchi, Mari Watanabe, Yasuo Akebiyama, Takanori Kubo, Bakarova Rumiana, Zhivko Zhelev, Hideki Ohba, Masayuki Fujii
- Organizer
  膜透過ペプチド国際ミニシンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18550158
[Presentation] 新規多価陽イオン遺伝子導入剤2006
- Author(s)
  高須奏江, 土井佳子, 清水政道, 原口正人, 明日山康生, 大庭英樹, 藤井政幸
- Organizer
  遺伝子・デリバリー研究会第6回シンポジウム
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18550158
[Presentation] 新規芳香族性多価陽イオン遺伝子導入剤2006
- Author(s)
  徳都, 上園由希子, 大上博子, 岩本友樹, 高須奏江, 土井佳子, 清水政道, 原口正人, 明日山康生, 大庭英樹, 藤井政幸
- Organizer
  遺伝子・デリバリー研究会第6回シンポジウム
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18550158
[Presentation] 芳香族多価陽イオン性新規遺伝子導入剤の開発2006
- Author(s)
  徳都, 土井佳子, 清水政道, 原口正人, 明日山康生, 大庭英樹, 藤井政幸
- Organizer
  第43回化学関連支部合同九州大会
- Place of Presentation
  北九州
- Year and Date
  2006-07-08
- Data Source
  KAKENHI-PROJECT-18550158
[Presentation] Antisense Inhibition of Human Telomerase by Phosphorothioate Oligonucleotide-Peptide Conjugates2006
- Author(s)
  Mari Watanabe, Yasuo Akebiyama, Takanori Kubo, Bakalova Rumiana, Zhivko Zhelev, Hideki Ohba, Masayuki Fujii
- Organizer
  第16回アンチセンスシンポジウム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18550158
[Presentation] 多価陽イオン性新規遺伝子導入剤の開発2006
- Author(s)
  岩本友樹, 土井佳子, 清水政道, 原口正人, 明日山康生大庭英樹, 藤井政幸
- Organizer
  第43回化学関連支部合同九州大会
- Place of Presentation
  北九州
- Year and Date
  2006-07-08
- Data Source
  KAKENHI-PROJECT-18550158
[Presentation] 陽イオン性新規遺伝子導入剤の開発2006
- Author(s)
  高須奏江, 土井佳子, 清水政道, 原口正人, 明日山康生, 大庭英樹, 藤井政幸
- Organizer
  第43回化学関連支部合同九州大会
- Place of Presentation
  北九州
- Year and Date
  2006-07-08
- Data Source
  KAKENHI-PROJECT-18550158
[Presentation] Specific Suppression of Bcr/abl Gene in Human Cells by synthetic DNA Enzymes2006
- Author(s)
  Kengo Takamori, Takanori Kubo, Hideki Ohba, Masayuki Fujii
- Organizer
  The Fukuoka Symposium, New Horizon of Natural Product and Biological Chemistries
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-18550158
[Presentation] 芳香族陽イオン性新規遺伝子導入剤の開発2006
- Author(s)
  大上博子, 土井佳子, 清水政道, 原口正人, 明日山康生, 大庭英樹, 藤井政幸
- Organizer
  第43回化学関連支部合同九州大会
- Place of Presentation
  北九州
- Year and Date
  2006-07-08
- Data Source
  KAKENHI-PROJECT-18550158
[Presentation] 核酸とペプチドの機能融合によるbcr/abl遺伝子サイレンシング
- Author(s)
  藤井政幸他2名
- Organizer
  第49回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] 塩基性両親媒性ペプチドと二重鎖核酸との相互作用
- Author(s)
  藤井政幸他3名
- Organizer
  第49回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] CATIONIC CHARGE ON SIRNA AND RNAI EFFECT
- Author(s)
  Ayumi Takashina, Hikari Kayano, Tomohiro Emi, Kana Murakami, Noriko Ogawa, Jumpei Ariyoshi, Asako Yamayoshi and Masayuki Fujii
- Organizer
  XXI Round Table on Chemical Biology of Nucleic Acids
- Place of Presentation
  ポズナン大学（ポーランド、ポズナン）
- Year and Date
  2014-08-24 – 2014-08-29
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] siRNA-ペプチド複合体の細胞内導入と遺伝子サイレンシング効果
- Author(s)
  萱野光、苗村円佳、高科あゆみ、神武洋二郎、森田資隆、藤井政幸
- Organizer
  第4回CSJ化学フェスタ2014
- Place of Presentation
  タワーホール舟堀（東京都江戸川区）
- Year and Date
  2014-10-14 – 2014-10-16
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] 新規両親媒性ペプチドによるsiRNAの無毒性細胞導入とhTERT遺伝子サイレンシング
- Author(s)
  藤井政幸他2名
- Organizer
  第49回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場
- Data Source
  KAKENHI-PROJECT-22550159
[Presentation] GENE SILENCING BY CATIONIC SIRNA
- Author(s)
  Ayumi Takashina, Hikari Kayano, Tomohiro Emi, Madoka Naemura, Yojiro Kotake, Jumpei Ariyoshi, Asako Yamayoshi, Akira Murakami and Masayuki Fujii
- Organizer
  The 41st International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  北九州国際会議場(福岡県北九州市）
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] EFFICIENT TRANSFECTION OF SIRNA BY DESIGNED PEPTIDES
- Author(s)
  Hikari Kayano, Ayumi Takashina, Madoka Naemura, Yojiro Kotake, Yasutaka Morita and Masayuki Fujii
- Organizer
  The 41st International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  北九州国際会議場(福岡県北九州市）
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] カチオン性siRNAの遺伝子サイレンシング効果
- Author(s)
  高科あゆみ、萱野光、江見友裕、苗村円佳、神武洋二郎、有吉純平、山吉麻子、村上章、藤井政幸
- Organizer
  アンチセンス・遺伝子・デリバリーシンポジウム2014
- Place of Presentation
  東京医科歯科大学（東京都文京区）
- Year and Date
  2014-09-08 – 2014-09-09
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] Synthesis and Gene Silencing by siRNA-Peptide Conjugates
- Author(s)
  Ayumi Takashina, Tomoniro Emi, Hikaru Kayano and Masayuki Fujii
- Organizer
  EMBO Conference, Chemical Biology 2014
- Place of Presentation
  ハイデルベルグEMBL（ドイツ、ヘイデルベルグ市）
- Year and Date
  2014-08-20 – 2014-08-23
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] カチオン修飾siRNAによる遺伝子サイレンシング効果
- Author(s)
  藤井　政幸・高科あゆみ・苗村円佳・神武洋二郎・山吉麻子・有吉純平・村上章
- Organizer
  日本化学会第95春季年会
- Place of Presentation
  日本大学船橋キャンパス（千葉県舟橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25410182
[Presentation] ハイブリッドペプチドによるsiRNAの無毒性細胞内デリバリーと遺伝子サイレンシング
- Author(s)
  小幡　淳一、高科　あゆみ、藤明　修太郎、藤井　政幸
- Organizer
  遺伝子・デリバリー研究会シンポジウム
- Place of Presentation
  帝京大学板橋キャンパス（東京都板橋区）
- Data Source
  KAKENHI-PROJECT-25410182

1. SUGIMOTO Naoki (60206430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. KAWAKAMI Junji (40289012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. MATSUI Jun (10264954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 麻生真理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 片山勉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUJII Masayuki 藤井 政幸

Research Projects

Research Products

Co-Researchers

Exploration of optimized chemical structure of siRNA based on the functional structure of human argonaute 2 proteinPrincipal Investigator

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Controlled intracellular delivery of Multi-functional siRNA and gene silencingPrincipal Investigator

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Control of genetic expression by conjugate siRNA delocalized in cytoplasmPrincipal Investigator

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Evaluation of RNA cleavage reaction based on the prediction parameters for nucleic acid structures

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DEVELOPMENT OF THERAPUETIC AGENTS AGAINST VERO TOXIN PRODUCED BY E. COLIPrincipal Investigator

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DEVELOPMENT OF RNA ANALOG INHIBITORS AGAINST VERO TOXIN PRODUCED BY E. COLIPrincipal Investigator

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[Book] 核酸医薬の創製と応用展開第III編 DDS 第6章 新規ペプチドによるsiRNAの無毒性細胞導入2016

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[Book] 遺伝子治療・診断の最先端技術と新しい医薬品・診断薬の開発2014

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[Book] 第4版マクマリー・生物有機化学（共訳）2014

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[Journal Article] 核酸医薬の分子デザイン；化学修飾、コンジュゲート、複合体2016

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NAID

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[Journal Article] Gene Silencing by Chemically Modified siRNAs Bearing Cationic Charge on 5’-End2015

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[Journal Article] Gene Silencing by miRNA-like siRNAs Bearing Mismatches and Bulges2015

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[Journal Article] Bioconjugation of oligodeoxynucleotides carrying 1,4-dicarbonyl groups via reductive amination with lysine residues2015

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DOI

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[Journal Article] Rational Design of siRNA by Chemical Modification and Conjugation2015

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[Journal Article] Synthesis, purification and delivery into mammalian cells of phosphoryl guanidine oligonucleotides (PGO) with either DNA or 2'-OMe RNA backbone2015

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FUJII Masayuki 藤井政幸

[Book] 核酸医薬の創製と応用展開第III編 DDS　第6章新規ペプチドによるsiRNAの無毒性細胞導入2016