IMAMURA Takuroh 今村卓郎

Researcher Number	60203329
Other IDs
Affiliation (based on the past Project Information) *help	2014: 宮崎大学, 医学部, 准教授 2014: 宮崎大学, 医学部内科学講座, 准教授 2009 – 2011: 宮崎大学, 医学部, 准教授 2003 – 2009: Miyazaki Medical College, University of Miyazaki, First Department of Internal Medicine, Assistant Professor, 医学部, 講師 2002: Miyazaki Medical College, 1st Dept Intern Med, Lecturer, 医学部, 講師 1998 – 2001: 宮崎医科大学, 医学部, 助手
Review Section/Research Field	Except Principal Investigator Human pathology / Human pathology / Biological Sciences
Keywords	Except Principal Investigator 動脈硬化 / 急性冠症候群 / Immunohistochemistry / 免疫染色 / 冠動脈アテレクトミー / アテローム血栓症 / ADAMTS-13 / Ecto-ATPDase / ecto-ATPDase / CD39 … More / RAMP / CRLR / Histopathology / Atherosclerosis / 炎症 / 冠動脈プラーク / 組織病理学 / 血栓 / 動脈硬化症 / 心筋梗塞 / 病理学 / 血栓症 / 酸化ストレス / 血小板 / rabbit femoral artery / Flow chamber / Acute myocardial infarction / Von Willebrand factor / Atherothroinhosis / 冠動脈吸引血栓 / von Willebrand factor / 血栓イメージング / 共焦点顕微鏡 / Coronary plaque / Vasoconstriction / Platelets / Acute coronary syndrome / 血管収縮 / Gene transfer / Adenovirus vector / Plaque instability / Directional atherectomy / Acute coronary syndromes / 剖検症例冠動脈 / 遺伝子導入 / アデノウイルスベクター / プラーク不安定化 / 冠動脈アテレクトミー(DCA) / directional coronary atherectomy / complements / C-reactive protein / coronary atheroscierosis / 狭心症 / C反応性タンパク質 / 補体 / C反応性蛋白 / 冠動脈硬化 / therapeutic application / intermediate form / gene manipulation / central action / locally-acting hormone / adrenomedullin / C末端アミド化 / 血管作動性ペプチド / 循環調節因子 / ラジオイムノアッセイ / 受容体 / 心筋の蛋白合成 / AM-Gly(iAM) / C-キナーゼ / アンジオテンシンII / 新規生理活性ペプチド / 生理活性ペプチド / PAMP / IRMA / コンビナントAM / AM遺伝子欠損マウス / 心線維芽細胞 / 心筋細胞 / AM遺伝子過剰発現マウス / 局所調節因子 / アミド化酵素 / AM-Gly / 水電解質調節 / 血圧調節 / AM受容体 / CGRP / アドレノメデュリン / Myocardial infarction / Thrombosis / マクロファージ / ポドプラ二ン / CLEC-2 / ポドプラニン / 血栓形成 / 病理組織学 / ヒトの病理組織標本 / real time PCR / 吸引血栓 / 循環器 / 人体病理 / 病理 / 糖尿病 / 血小板凝集 / フローチャンバー法 / 臨床病理当的検討 / 動脈血栓モデル / 免疫組織化学 / 臨床病理学的検討 / RANKL / Osteoprotegerin / RANKL system / OPG / 血流解析 / 炎症性サイトカイン / 凝固線溶系 Less

Involvement of Podoplanin/CLEC-2 in atherothrombosis
- Principal Investigator
  
  KINTA Hatakeyama
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Nara Medical University
  University of Miyazaki
Mechanism of atherothrombosis in diabetes mellitus
- Principal Investigator
  
  ASADA Yujiro
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  University of Miyazaki
Pathogenesis of atherothrombosis
- Principal Investigator
  
  ASADA Yujiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  University of Miyazaki
The role of OPG/RANKL system in the pathogenesis of atherothrombosis
- Principal Investigator
  
  HATAKEYAMA Kinta
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  University of Miyazaki
Involvement of ADAMTS-13 in the pathogenesis of acute coronary syndrome
- Principal Investigator
  
  HATAKEYAMA Kinta
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  University of Miyazaki
Role of Ecto-ATPDase in the Pathogenesis of Acute Coronary Syndrome
- Principal Investigator
  
  ASADA Yujiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  University of Miyazaki
Expression of CD39 in coronary atherosclerotic lesions
- Principal Investigator
  
  HATAKEYAMA Kinta
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  University of Miyazaki
  宮崎医科大学
Role of complements and C-reactive protein on acute coronary syndromes
- Principal Investigator
  
  ASADA Yujiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  (Miyazaki Medical College) University of Miyazaki
Pathophysiological Role of Adrenomedullin in Cardiovascular Disease and Therapeutic Application of Adrenomedullin
- Principal Investigator
  
  ETO Tanenao
- Project Period (FY)
  1998 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Miyazaki Medical College

All 2010 2009 2008

All Journal Article Presentation Patent

[Journal Article] Reciprocal contribution of pentraxin 3 and c-reactive protein to obesity and metabolic syndrome.2010
- Author(s)
  Ogawa T, Kawano Y, Imamura T, Kawakita K, Sagara M, Matsuo T, Kakitsubata Y, Ishikawa T, Kitamura K, Hatakeyama K, Asada Y, Kodama T
- Journal Title
  
  Obesity (Silver Spring) 18
  
  Pages: 1871-1874
- Data Source
  KAKENHI-PROJECT-20590344
[Journal Article] Disturbed blood flow induces erosive injury to smooth muscle cell-rich neointima and promotes thrombus formation in rabbit femoral artery.2010
- Author(s)
  Sumi T, Yamashita A, Matsuda S, Goto S, Nishihira K, Furukoji E, Sugimura H, Kawahara H, Imamura T, Kitamura K, Tamura S, Asada Y.
- Journal Title
  
  J Thromb Haemost. 8
  
  Pages: 1394-1402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390102
[Journal Article] Plasma Pentraxin 3, but not High-sensitivity C-reactive Protein, is a Useful Inflammatory Biomarker for Predicting Cognitive Impairment in Elderly Hypertensive Patients.2010
- Author(s)
  Yano Y, Matsuda S, Hatakeyama K, Sato Y,, Imamura T, Shimada K, Kodama T, Kario K, Asada Y
- Journal Title
  
  J Gerontol A Biol Sci Med Sci 65
  
  Pages: 547-552
- Data Source
  KAKENHI-PROJECT-20590344
[Journal Article] Kitamura Pressure-independent effects of pharmacological stimulation of soluble guanylate cyclase on fibrosis in pressure-overloaded rat heart.2009
- Author(s)
  Masuyama H, Tsuruda T, Sekita Y, Hatakeyama K, Imamura T, Kato J, Asada Y, Stasch JP
- Journal Title
  
  Hypertens Res 32
  
  Pages: 597-603
- Data Source
  KAKENHI-PROJECT-20590344
[Journal Article] Thrombin generation by intimal tissue factor contributes to thrombus formation on macrophage-rich neointima but not normal intima of hyperlipidemic rabbits.2009
- Author(s)
  Yamashita A, Matsuda S, Matsumoto T, Moriguchi-Goto S, Takahashi M, Sugita C, Sumi T, Imamura T, Shima M, Kitamura K, Asada Y.
- Journal Title
  
  Atherosclerosis. 206
  
  Pages: 418-426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390102
[Journal Article] Pharmacological Stimulation of Soluble Guanylate Cyclase Modulates Hypoxia Inducible Factor-lalpha in Rat Heart.2009
- Author(s)
  Tsuruda T, Hatakeyama K, Masuyama H, Sekita Y, Imamura T, Asada Y, Kitamura K
- Journal Title
  
  Am J Physiol Heart Circ Physiol 297
- Data Source
  KAKENHI-PROJECT-20590344
[Journal Article] Serotonin induces vasoconstriction of smooth muscle cell-rich neointima through 5-hydroxytryptamine_2A receptor in rabbit femoral arteries.2008
- Author(s)
  Nishihira K, Yamashita A, Tanaka N, Moriguchi-Goto S, Imamura T, Ishida T, Kawashima S, Yamamoto R, Kitamura K, Asada Y.
- Journal Title
  
  J Thromb Haemost 6
  
  Pages: 1207-1214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390102
[Journal Article] Thioredoxin in coronary culprit lesions : possible relationship to oxidative stress and intraplaque hemorrhage.2008
- Author(s)
  Nishihira K, Yamashita A, Imamura T, Hatakeyama K, Sato Y, Nakamura H, Yodoi J, Ogawa H, Kitamura K, Asada Y.
- Journal Title
  
  Atherosclerosis. 201
  
  Pages: 360-367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390102
[Journal Article] Thioredoxin in coronary culprit lesions : possible relationship to oxidative stress and intraplaque hemorrhage.2008
- Author(s)
  Nishihira K, 山下篤, Imamura T, 畠山金太, 佐藤勇一郎, Nakamura H, Yodoi J, Ogawa H, Kitamura K, 浅田祐士郎
- Journal Title
  
  Atherosclerosis 201
  
  Pages: 360-367
- Data Source
  KAKENHI-PROJECT-20590344
[Patent] ペントラキシン3またはペントラキシン3変異体を含む、血小板凝集抑性剤、血栓形成剤および循環器疾患の治療薬2008
- Inventor(s)
  浅田祐士郎、畠山金太、今村卓郎、後藤清香、児玉龍彦、相良三奈
- Industrial Property Rights Holder
  国立大学法人宮崎大学株式会社ペルセウスプロテオミクス
- Industrial Property Number
  2008-255988
- Filing Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-20590344
[Patent] ペントラキシンまたはペントラキシン3変異体を含む、血小板凝集抑制剤、血栓形成抑制剤および循環・器疾患の治療薬2008
- Inventor(s)
  浅田祐士郎、畠山金太、今村卓郎、後藤清香、児玉龍彦、相良三奈
- Industrial Property Rights Holder
  国立大学法人宮崎大学、国立大学法人東京大学、株式会社ペルセウス
- Industrial Property Number
  2008-255988
- Filing Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-20390102
[Presentation] PTX3 is involved in the pathogenesis of unstable plaque associated with intraplaque hemorrhage.2010
- Author(s)
  Hatakeyama K, Matsuura Y, Imamura T, Tsuruda T, Nishihira K, Shibata Y, Kodama T, Asada Y
- Organizer
  European Society of Cardiology Congress
- Place of Presentation
  Stockholm
- Data Source
  KAKENHI-PROJECT-20590344
[Presentation] Site specificity of adventitial inflammation during the development of atherosclerosis in apolipoprotein E knockout mice.2010
- Author(s)
  Sakamoto S, Tsuruda T, Hatakeyama K, Sekita Y, Imamura T, Asada Y, Kitamura K
- Organizer
  European Society of Cardiology Congress
- Place of Presentation
  Stockholm
- Data Source
  KAKENHI-PROJECT-20590344
[Presentation] Serotonin induces vasoconstriction of smooth muscle cell?rich neointima through 5?hydroxytryptamine 2A receptor in rabbit femoral arteries.2009
- Author(s)
  Nishihira K, Imamura T, Nakama T, Mine D, Shimomura M, Nomura K, Kuriyama N, Matsuyama A, Ishikawa T, Shibata Y, Kitamura K, Asada Y.
- Organizer
  The 73rd Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  大阪
- Year and Date
  2009-03-21
- Data Source
  KAKENHI-PROJECT-20390102
[Presentation] Analysis of plaque composition in culprit lesion obtained by directional coronary atherectomy; From viewpoints of gender difference.2009
- Author(s)
  Matsuura Y, Imamura T, Hatakeyama K, Tsuruda T, Nishihira K, Shibata Y, Kitamura K, Asada Y
- Organizer
  第73回日本循環器学会総会
- Place of Presentation
  大阪
- Year and Date
  2009-03-21
- Data Source
  KAKENHI-PROJECT-20590344

1. SATO Yuichiro (90347055)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
2. HATAKEYAMA Kinta (60325735)

# of Collaborated Projects: 6 results

# of Collaborated Products: 8 results
3. MARUTSUKA Kosuke (00239154)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. ASADA Yujiro (70202588)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
5. YAMASHITA Atsushi (90372797)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
6. TSURUDA Toshihiro (10389570)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. SHIOMI Masashi (50226106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ETO Tanenao (10038854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KATO Johji (20274780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KANNAN Hiroshi (00049058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KURIHARA Hiroki (20221947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IMAMURA Takuroh 今村 卓郎

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[Journal Article] Reciprocal contribution of pentraxin 3 and c-reactive protein to obesity and metabolic syndrome.2010

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Journal Title

Data Source

[Journal Article] Disturbed blood flow induces erosive injury to smooth muscle cell-rich neointima and promotes thrombus formation in rabbit femoral artery.2010

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Journal Title

Data Source

[Journal Article] Plasma Pentraxin 3, but not High-sensitivity C-reactive Protein, is a Useful Inflammatory Biomarker for Predicting Cognitive Impairment in Elderly Hypertensive Patients.2010

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Journal Title

Data Source

[Journal Article] Kitamura Pressure-independent effects of pharmacological stimulation of soluble guanylate cyclase on fibrosis in pressure-overloaded rat heart.2009

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Journal Title

Data Source

[Journal Article] Thrombin generation by intimal tissue factor contributes to thrombus formation on macrophage-rich neointima but not normal intima of hyperlipidemic rabbits.2009

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Data Source

[Journal Article] Pharmacological Stimulation of Soluble Guanylate Cyclase Modulates Hypoxia Inducible Factor-lalpha in Rat Heart.2009

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Data Source

[Journal Article] Serotonin induces vasoconstriction of smooth muscle cell-rich neointima through 5-hydroxytryptamine_2A receptor in rabbit femoral arteries.2008

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[Journal Article] Thioredoxin in coronary culprit lesions : possible relationship to oxidative stress and intraplaque hemorrhage.2008

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IMAMURA Takuroh 今村卓郎