Jisaka Mitsuo 地阪光生

… Alternative Names

JISAKA Mitsuo 地坂光生

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Researcher Number	60243424
Other IDs
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Affiliation (Current)	2025: 島根大学, 学術研究院農生命科学系, 准教授
Affiliation (based on the past Project Information) *help	2016: 島根大学, 生物資源科学部, 准教授 2007 – 2009: Shimane University, 生物資源科学部, 准教授 1998 – 2004: 島根大学, 生物資源科学部, 助教授 1994: Shimane University, Faculty of Agriculture, Associate Professor, 農学部, 助教授 1993: 島根大学, 農学部, 助手
Review Section/Research Field	Principal Investigator Food science / Functional biochemistry / Bioproduction chemistry/Bioorganic chemistry Except Principal Investigator 食品科学・栄養科学 / Applied biochemistry
Keywords	Principal Investigator リポキシゲナーゼ / 神経保護因子 / FOX / ドコサヘキサエン酸 / n-3系脂肪酸 / リノール酸 / アラキドン酸 / 非ヘム鉄リガンド / リガンド / アラニン … More / ヒスチジン / アスパラギン / セリン / 8-リポキシゲナーゼ / 鉄リガンド / 傷害ストレス / ジビニルエーテル / ジャガイモ塊茎 / コルネル酸合成酵素 / コルネル酸 / 過酸化脂質 / 環境ストレス … More Except Principal Investigator プロスタグランジン / プロスタノイド / アラキドン酸カスケード / シクロオキシゲナーゼ / prostaglandin / エイコサノイド / アラキドン酸 / adipocyte / 脂肪細胞 / cyclooxygenase / アイソフォーム / arachidonic acid / Madin-Darbyイヌ腎臓細胞株 / 必須脂肪酸 / 形質転換細胞 / PGJ2誘導体 / アンチセンス / COX-2 / COX-1 / 成熟期 / 6-ケト-PGF1α / 脂肪細胞形成 / PPARgamma / IP受容体 / プロスタグランジンI2 / プロスタサイクリン / 分化誘導 / 成熟脂肪細胞 / 前駆脂肪細胞 / preadipogenic cells / PGI2 / life stage / IP receptor / adipogenesis / prostacyclin / nuclear receptor / abietic acid / programmed cell death / 3T3-L1 preadipogenic cell line / eicosanoids / 15-デオキシ-Δ^<12,14>-PGJ_2 / 内因性リガンド / PPARγ / PGD合成酵素 / 3T3-L1細胞 / 酸化ストレス / マウス3T3-L1 / アディポネクチン / インスリン / アスピリン / イソプロスタン / 核内受容体 / アビエチン酸 / プログラム細胞死 / マウス3T3-L1前駆脂肪細胞株 / Madin-Darby canine kidney cell line / chimera / 15-lipoxygenase / 8-lipoxygenase / lipoxygenase / reverse transcriptase-polymerase chain reaction / リノール酸 / Maclin-Darbyイヌ腎臓上皮性細胞株 / 逆転写・ポリメラーゼ連鎖反応 / アラキド酸 / エイコサペンタエン酸 / 不飽和化反応 / アポトーシス / RT-PCR / キメラ酵素 / 15-リポキシゲナーゼ / 8-リポキシゲナーゼ / リポキシゲナーゼ / 逆転写-ポリメラーゼ連鎖反応 / arachidonate cascades / phospholipase D / prostaglandin endoperoxide synthase / phorbol diester / prostanoid / Madin-Darby canine kidney cells / essential fatty acid / ホスファチジルエタノールアミン / 膜リン脂質 / 細胞情報伝達機構 / ホルボールジエステル / プロスタグランジンエンドペルオキシド合成酵素 / リン脂質 Less

Regulation and role of the arachidonate cascade reaction at different life stages of adipocytes
- Principal Investigator
  
  Yokota Kazushige
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Shimane University
Metabolism of n-3 polyunsaturated fatty acids by lipoxygenases and production of novel bioactive agentsPrincipal Investigator
- Principal Investigator
  
  JISAKA Mitsuo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Shimane University
The regulatory mechanism of the arachidonate cascade controlling the differentiation and quality changes in in adipocytes
- Principal Investigator
  
  YOKOTA Kazushige
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  Shimane University
リポキシゲナーゼにおける非ヘム鉄リガンドの反応修飾機能の解析Principal Investigator
- Principal Investigator
  
  地阪光生
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Shimane University
Biosynthetic mechanism of informational lipid molecules in the signal transduction of mammalian cells and its molecular regulation by food functional agents
- Principal Investigator
  
  YOKOTA Kazushige
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  Shimane University
植物のリポキシゲナーゼ代謝反応系と環境ストレス応答に関する研究Principal Investigator
- Principal Investigator
  
  地阪光生
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Shimane University
The regulation of the gene expression of the enzymes in arachidonate cascades by dietary factors
- Principal Investigator
  
  YOKOTA Kazushige
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  Faculty of Agriculture, Shimane University

All 2017 2016 2014 2013 2010 2009 2008 2007 2005 Other

All Journal Article Presentation Book

[Book] Analysis of highly polymeric proanthocyanidins from seed shells of Japanese horse chestnut and their health benefits. “ Procyanidins: Characterisation, Antioxidant Properties and Health Benefits, Series: Biochemistry Research Trends”, (Edited by Chedea, VS)2016
- Author(s)
  Yokota K, Kimura H, Ogawa S, Jisaka, M.
- Total Pages
  11
- Publisher
  Nova Science Publishers, New York,
- Data Source
  KAKENHI-PROJECT-25450128
[Journal Article] Pretreatment of cultured preadipocytes with arachidonic acid during the differentiation phase without a cAMP-elevating agent enhances fat storage after the maturation phase2016
- Author(s)
  Khan, F., Seyda, P. K., Nartey, M. N. N., Rahman, M. S., Islam, M. S., Nishimura, K., Jisaka, M., Shono, F., and Yokota, K.
- Journal Title
  
  Prostaglandins Other Lipid Mediat.
  
  Volume: 123 Pages: 16-27
- DOI
  10.1016/j.prostaglandins.2016.02.003
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-14F04092, KAKENHI-PROJECT-25450128
[Journal Article] Stimulation of fat storage by prostacyclin and selective agonists of prostanoid IP receptor during the maturation phase of cultured adipocytes2016
- Author(s)
  Khan, F., Syeda, P. K., Nartey, M. N. N., Rahman, M. S., Islam, M. S., Nishimura, K., Jisaka, M., Shono, F., and Yokota, K.
- Journal Title
  
  Cytotechnology
  
  Volume: - Issue: 6 Pages: 2417-2429
- DOI
  10.1007/s10616-016-9960-7
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450128, KAKENHI-PROJECT-14F04092
[Journal Article] Endogenous synthesis of prostacyclin was positively regulated during the maturation phase of cultured adipocytes2014
- Author(s)
  Rahman, M. S., Khan, F., Syeda, P. K., Nishimura, K., Jisaka, M., Nagaya, T., Shono, F., and Yokota, K.
- Journal Title
  
  Cytotechnology
  
  Volume: 66 Issue: 4 Pages: 635-646
- DOI
  10.1007/s10616-013-9616-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13F03091, KAKENHI-PROJECT-25450128
[Journal Article] Up-regulation of adipogenesis in adipocytes expressing stably cyclooxygenase-2 in the antisense direction2010
- Author(s)
  X. Chu, K. Nishimura, M. Jisaka, T. Nagaya, F. Shono, K. Yokota
- Journal Title
  
  Prostaglandins and Other Lipid Mediators 91
  
  Pages: 1-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580138
[Journal Article] Development of enzyme-linked immunosorbent assay for 8-iso-prostaglandin F2(alpha), a biomarker of oxidative stress in vivo, and its application to the quantification in aged rats.2009
- Author(s)
  X. Chu, Y. Ageishi, K. Nishimura, M. Jisaka, T. Nagaya, F. Shono, K. Yokota
- Journal Title
  
  Journal of Pharmacological and Biomedical Analysis 50
  
  Pages: 911-916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580138
[Journal Article] Tumor-Suppressive Lipoxygenase Inhibit the Expression of c-myc mRNA Coding Region Determinant-Binding Protein/Insulin-Like 5 Growth Factor II mRNA-Binding Protein 1 in Human Prostate Carcinoma PC-3 Cells.2009
- Author(s)
  Y. Kawakami, N. Kubota, N. Ekuni, T. Suzuki-Yamamoto, M. Kimoto, H. Yamashita, H. Tsuji, T. Yoshimoto, M. Jisaka, J. Tanaka, H.F. Fujimura, Y. Miwa, Y. Takahashi
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry 73
  
  Pages: 1811-1817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580138
[Journal Article] Measurement of Lipid Hydroperoxides by the Ferric-Xylenol Orange Method (2) Application to Lipoxygenase Assay.2009
- Author(s)
  K. Fukuzawa, M. Sano, K. Akai, J. Morishige, A. Tokumura, M. Jisaka
- Journal Title
  
  Journal of Nutritional Science and Vitaminology 55
  
  Pages: 92-98
- NAID
  110007110606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580138
[Journal Article] Suppression of adipogenesis program in cultured preadipocytes transfected stably with cyclooxygenase isoforms.2009
- Author(s)
  X. Chu, L. Xu, K. Nishimura, M. Jisaka, T. Nagaya, F. Shono, K. Yokota
- Journal Title
  
  Biochimica et Biophysica Acta 1791
  
  Pages: 273-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580138
[Journal Article] Double dioxygenation by mouse 8S-lipoxygenase : Formation of a potent peroxisome proliferator-activator receptor agonist.2005
- Author(s)
  M.Jisaka
- Journal Title
  
  Prostaglandins Other Lipid Mediat (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14560099
[Journal Article] Double dioxygenation by mouse 8S-lipoxygenase : Formation of a potent peroxisome proliferator-activator receptor a agonist2005
- Author(s)
  M.Jisaka
- Journal Title
  
  Prostaglandins and Other Lipid Mediators (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14560099
[Presentation] Exogenous arachidonic acid up-regulates adipogenesis program of cultured preadipocytes during the differentiation phase without a cAMP-elevating agent2017
- Author(s)
  Nartey, M. N. N., Syeda, P. K., Rahman, M. S., Chowdhury, M. M. I., Nishimura, K., Shimizu, H., Jisaka, M., Shono, F., and Yokota, K
- Organizer
  47th Annual Meeting of Chu-Shikoku Division in the Japan Society for Bioscience, Biotechnology, and Agrochemistry
- Place of Presentation
  島根大学松江キャンパス（松江市）
- Year and Date
  2017-01-28
- Data Source
  KAKENHI-PROJECT-25450128
[Presentation] 1.Stimulation of adipogenesis after the maturation phase by pretreatment of cultured preadipocytes with arachidonic acid during the differentiation phase without a cAMP-elevating agent2016
- Author(s)
  Khan K, Nartey MNN, Syeda, PK, Rahman MS, Nishimura K, Jisaka M, Shimizu H, Shono F, Yokota K
- Organizer
  The 89th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-25450128
[Presentation] Biosynthesis of prostacyclin and its action is up-regulated during the maturation phase of adipocytes2014
- Author(s)
  Khan, F., Rahman, M. S., Fatema, P. K. S. K., Islam, M. S., Nishimura, K., Jisaka, M., Nagaya, T., Shono, F., and Yokota, K.
- Organizer
  40th Annual Meeting of Chu-Shikoku Division in the Japan Society for Bioscience, Biotechnology, and Agrochemistry
- Place of Presentation
  徳島大学総合科学部（徳島市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-25450128
[Presentation] 11-Deoxy-11-methylene-prostaglandin (PG) D2 exerts pro-adipogenic effect on cultured adipocytes during the maturation phase through cellular mechanism different from that of natural PGD22014
- Author(s)
  Fatema, P. K. S. K., Islam, M. S., Khan, F., Nishimura, K., Jisaka, Nagaya, T., Shono, F., and Yokota, K.
- Organizer
  40th Annual Meeting of Chu-Shikoku Division in the Japan Society for Bioscience, Biotechnology, and Agrochemistry
- Place of Presentation
  徳島大学総合科学部（徳島市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-25450128
[Presentation] Biosynthesis of prostacyclin serving as a biomarker for enhanced adipogenesis program in cultured adipocytes2013
- Author(s)
  Rahman, M. S., Khan, F., Syeda, P. K., Nishimura, K., Jisaka, M., Nagaya, T., Shono, F., and Yokota, K.
- Organizer
  13th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases
- Place of Presentation
  San Juan, Puerto Rico, USA
- Data Source
  KAKENHI-PROJECT-25450128
[Presentation] Stimulation of adipogenesis with 11-deoxy-11-methylene-PGD2, a stable, isosteric analogue of PGD2, during the maturation phase of adipocytes2013
- Author(s)
  Fatema, P. K. S. K., Khan, F., Nishimura, K., Jisaka, M., Nagaya, T., Shono, F., and Yokota, K.
- Organizer
  The 86th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-25450128
[Presentation] Stable transfection of cultured preadipocytes with cyclooxygenase-1 in the antisense direction up-regulates adipogenesis during the maturation phase of adipocytes2013
- Author(s)
  Rahman, M. S., Syeda, P. K. Khan, F., Nishimura, K., Jisaka, M., Nagaya, T., Shono, F., and Yokota, K.
- Organizer
  13th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases
- Place of Presentation
  San Juan, Puerto Rico, USA
- Data Source
  KAKENHI-PROJECT-25450128
[Presentation] Physiological function of skin-related lipoxygenases2009
- Author(s)
  Mitsuo Jisaka
- Organizer
  4th International Conference on Phospholipase A2 and Lipid Mediators (PLM2009)
- Place of Presentation
  学術総合センター
- Year and Date
  2009-05-25
- Data Source
  KAKENHI-PROJECT-19580138
[Presentation] Physiological function of skin-related lipoxygenases2009
- Author(s)
  Mitsuo Jisaka
- Organizer
  4^<th> International Conference on Phopholipase A2 and Lipid Mediators
- Place of Presentation
  学術総合センター
- Year and Date
  2009-05-25
- Data Source
  KAKENHI-PROJECT-19580138
[Presentation] 表皮系リポキシゲナーゼによるドコサヘキサエン酸代謝の可能性2008
- Author(s)
  細川歩、若槻恵、西村浩二、長屋敦、横田一成、地阪光生
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名城大学天白キャンパス(名古屋)
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19580138
[Presentation] マウス8S-リポキシゲナーゼによるドコサヘキサエン酸の酸素添加反応.2008
- Author(s)
  地阪光生、細川歩、西村浩二、長屋敦、横田一成
- Organizer
  第50回日本脂質生化学会
- Place of Presentation
  徳島県郷土文化会館
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19580138
[Presentation] 表皮系リポキシゲナーゼによるドコサヘキサエン酸代謝の可能性2008
- Author(s)
  細川歩、地阪光生、, 他4名
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名城大学天白キャンパス
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19580138
[Presentation] マウス8S-リポキシゲナーゼによるドコサヘキサエン酸の酸素添加2008
- Author(s)
  地阪光生
- Organizer
  日本脂質生化学会
- Place of Presentation
  徳島県郷土文化会館
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-19580138
[Presentation] Comparison of the substrate-binding sites of mouse 8-lipoxygenase and human 15-lipoxygenase-2 based on oxygenation of methyl arachidonate and methyl linoleate.2007
- Author(s)
  M. Jisaka, K. Nishimura, T. Nagaya, K. Yokota
- Organizer
  The 10th Conference on the Bioactive Lipids in Cancer, Inflammation, and Related Diseases
- Place of Presentation
  La Centre Sheraton Hotel (Montrteal, Canada)
- Year and Date
  2007-09-17
- Data Source
  KAKENHI-PROJECT-19580138
[Presentation] Prostaglandin J2, natural bioactive lipid, modulates adipocyte inflammation. International Conference on Updates on Natural Products in Medicine and Healthcare Systems
- Author(s)
  Hossain, M. S., Chowdhury, A. A., Jisaka, M. Nagaya, T., and Yokota, K.
- Organizer
  International Conference on Updates on Natural Products in Medicine and Healthcare Systems
- Place of Presentation
  Khulna, Bangladesh
- Data Source
  KAKENHI-PROJECT-25450128
[Presentation] Up-regulation of prostacyclin biosynthesis and its response after the maturation phase of adipocytes
- Author(s)
  Rahman, M. S., Khan, F., Fatema, P. K. S. K., Islam, M. S., Nishimura, K., Jisaka, M., Nagaya, T., Shono, F., and Yokota, K.
- Organizer
  The 87th Annual Meeting of the Japanese Biochemical Society
- Place of Presentation
  京都国際会議場（京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25450128
[Presentation] Biosynthesis of prostaglandin I2 at different life stages of cultured adipocytes as determined by the immunological assay for its stable hydrolysis product.
- Author(s)
  Khan, F., Rahaman, M. S., Syeda, P. K., Nishimura, K., Jisaka, M., Nagaya, T., Shono, F., and Yokota, K.
- Organizer
  日本農芸化学会中四国支部第36回講演会
- Place of Presentation
  松江
- Data Source
  KAKENHI-PROJECT-25450128

1. YOKOTA Kazushige (90158361)

# of Collaborated Projects: 5 results

# of Collaborated Products: 20 results
2. NISHIMURA Kohji (30304257)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
3. TAKINAMI Koichi (40243422)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. NAGAYA Tsutomu (50284021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. TAKAHASHI Yoshitaka (10236333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. HUKUZAWA Kenji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHONO Fumiaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
8. ISLAM Mohammad

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Jisaka Mitsuo 地阪 光生

JISAKA Mitsuo 地坂 光生

Research Projects

Research Products

Co-Researchers

Regulation and role of the arachidonate cascade reaction at different life stages of adipocytes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Metabolism of n-3 polyunsaturated fatty acids by lipoxygenases and production of novel bioactive agentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The regulatory mechanism of the arachidonate cascade controlling the differentiation and quality changes in in adipocytes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

リポキシゲナーゼにおける非ヘム鉄リガンドの反応修飾機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biosynthetic mechanism of informational lipid molecules in the signal transduction of mammalian cells and its molecular regulation by food functional agents

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

植物のリポキシゲナーゼ代謝反応系と環境ストレス応答に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The regulation of the gene expression of the enzymes in arachidonate cascades by dietary factors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Analysis of highly polymeric proanthocyanidins from seed shells of Japanese horse chestnut and their health benefits. “ Procyanidins: Characterisation, Antioxidant Properties and Health Benefits, Series: Biochemistry Research Trends”, (Edited by Chedea, VS)2016

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Pretreatment of cultured preadipocytes with arachidonic acid during the differentiation phase without a cAMP-elevating agent enhances fat storage after the maturation phase2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stimulation of fat storage by prostacyclin and selective agonists of prostanoid IP receptor during the maturation phase of cultured adipocytes2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endogenous synthesis of prostacyclin was positively regulated during the maturation phase of cultured adipocytes2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Up-regulation of adipogenesis in adipocytes expressing stably cyclooxygenase-2 in the antisense direction2010

Author(s)

Journal Title

Data Source

[Journal Article] Development of enzyme-linked immunosorbent assay for 8-iso-prostaglandin F2(alpha), a biomarker of oxidative stress in vivo, and its application to the quantification in aged rats.2009

Author(s)

Journal Title

Data Source

[Journal Article] Tumor-Suppressive Lipoxygenase Inhibit the Expression of c-myc mRNA Coding Region Determinant-Binding Protein/Insulin-Like 5 Growth Factor II mRNA-Binding Protein 1 in Human Prostate Carcinoma PC-3 Cells.2009

Author(s)

Journal Title

Data Source

[Journal Article] Measurement of Lipid Hydroperoxides by the Ferric-Xylenol Orange Method (2) Application to Lipoxygenase Assay.2009

Jisaka Mitsuo 地阪光生

JISAKA Mitsuo 地坂光生