KATO Kouichi 加藤孝一

… Alternative Names

加藤孝一カトウコウイチ

KATO Koichi 加藤孝一

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Researcher Number	60246931
Other IDs
Affiliation (Current)	2025: 日本大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2016: 日本大学, 薬学部, 教授 2014 – 2015: 日本大学, 薬学部, 准教授 2010 – 2012: 日本大学, 薬学部, 准教授 2008: Nihon University, 薬学部, 准教授 2002 – 2007: 日本大学, 薬学部, 講師 2006: 日本大学, 薬学部生物薬学科, 講師
Review Section/Research Field	Principal Investigator Risk sciences of radiation/Chemicals Except Principal Investigator Environmental pharmacy / Environmental pharmacy / Hygiene and public health / Environmental and hygienic pharmacy / Hygiene
Keywords	Principal Investigator クレアチニン / メチルアミン / クロラミン / 酸化ストレス / 大腸がん / 潰瘍性大腸炎 Except Principal Investigator ジメチルアルシン酸 / ジメチルヒ素 / ジメチルアルシン / メチル化代謝 … More / 酸化ストレス / ジメチルチオアルシン酸 / 3価ジメチルヒ素 / ジメチルモノチオアルシン酸 / ジメチルアルシン過酸化ラジカル / ジメチルアルシンラジカル / Dimethylarsine peroxy radical / Dimethylarsine radical / Dimethylarsine / Dimethylarsinic acid / Arsenic carcinogenesis / Environmental carcinogenesis / ジメチルヒ素化合粒 / ジメチルアシン / マウス短期肺発癌実験 / 発癌イニシエーション / 発癌プロモーション / ヒ素発癌機構 / 環境化学発癌 / metabolic mathylation / inorganic arsenics / arsenic carcinogenesis / oxidative stress / dimethylarsenic peroxy radical / trivalent dimethylated arsenic / dimethylarsinic acid / 発がんプロモーション / 8-OHdG / チミングリコール / 8-oxodG / 小核形成 / 無機ヒ素 / ヒ素発癌 / ジメチルヒ素フリーラジカル / 遺伝毒性 / 衛生 / 体細胞突然変異 / グルタチオンS-トランスフェラーゼ / 化学発がん / ハロゲン化炭化水素 / ジクロロメタン / 1,2-ジクロロプロパン / 胆管がん / アルセノ脂質 / 硫化水素 / HepaRG細胞 / カスパーゼ3/7 / ジメチルメルカプトアルシン / グルタチオン / ジメチル亜ヒ酸 / 代謝 / 腸内細菌 / アルセノシュガー / メタロミクス解析 / 毒性発現 / ヒ素化学形態分析 / ジメチルチオヒ素 / HPLC-ICP-MS / 代謝活性化 / チオヒ素 / 硫黄転移酵素 / ヒ素発がんリスク / 肺発がんプロモーション / 赤血球 / 発がん組織特異性 / ヘモグロビン / 鉄 / 肺組織特異性 / ヒ素過酸化ラジカル / ヒ素ラジカル / 肺発癌動物実験モデル / マウス / 有機金属 / 食品分析 / 生体分析 / 機能性樹脂 / 遷移金属 / アルカリ土類金属 / アルカリ金属 / 微量元素分析 Less

Metallomic analysis to elucidate the metabolism and biological effects of arsenic compounds contained in Seafood
- Principal Investigator
  
  YAMANAKA Kenzo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  Nihon University
Elucidation of the ultimate carcinogen associated with occupational cholangiocarcinoma
- Principal Investigator
  
  ENDO Ginji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  The Ohara Memorial Institute for Science of Labour
  Osaka City University
Possible metabolic activation of arsenic carcinogenesis ?New mode of activation of dimethylarsenic involved with sulfur atom-
- Principal Investigator
  
  YAMANAKA Kenzo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nihon University
難治性消化器疾患に関わる新規食生活要因の提言およびその病因論的考察Principal Investigator
- Principal Investigator
  
  加藤孝一
- Project Period (FY)
  2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Nihon University
Relationship between active arsenc species and tissues specificity in arsenic carcinogenesisq
- Principal Investigator
  
  YAMANAKA Kenzo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nihon University
微量金属の高精度分析法の開発:元素選択捕捉機能をもった樹脂の応用展開
- Principal Investigator
  
  ENDO Ginji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Osaka City University
Determination of ultimate substances on arsenic carcinogenesis and in vivo formation mechanisms of their substances
- Principal Investigator
  
  YAMANAKA Kenzo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nihon University
The role of active arsenic species produced by metabolic reduction of dimethylarsinic acid in genotoxicity and tumorigenesis : The contribution of dimethylarsenic radicals and dimethylarsenic peroxide
- Principal Investigator
  
  YAMANAKA Kenzo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nihon University

All 2017 2016 2015 2012 2011 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] A novel metabolic activation associated with glutathione in dimethylmonothioarsinic acid (DMMTAV)-induced toxicity obtained from in vitro reaction of DMMTAV with glutathione2016
- Author(s)
  Hidetoshi Kurosawa, Yasuyo Shimoda, Motofumi Miura, Koichi Kato, Kenzo Yamanaka, Akihisa Hata, Yuko Yamano, Yoko Endo, Ginji Endo
- Journal Title
  
  Journal of Trace Elementsin Medicine and Biology
  
  Volume: 33 Pages: 87-94
- DOI
  10.1016/j.jtemb.2015.10.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460176
[Journal Article] Ingestion of Hijiki sea weed and risk of arsenic poisoning.2006
- Author(s)
  Nakajima Y, Endo Y, Inoue Y, Yamanaka K, Kato K, Wanibuchi H, Endo G
- Journal Title
  
  Appl Organometal Chem 20(9)
  
  Pages: 557-564
- Data Source
  KAKENHI-PROJECT-17659178
[Journal Article] Specific induction of oxidative stress in terminal bronchiolar Clara cells during dimethylarsenic-induced lung tumor promoting process in mice.2005
- Author(s)
  Y.An, K.Kato, M.Nakano, H.Otsu, S.Okada, K.Yamanaka
- Journal Title
  
  Cancer Letters (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572114
[Journal Article] Specific induction of oxidative stress in terminal bronchiolar Clara cells during dimethylarsenic-induced lung tumor promoting process in mice.2005
- Author(s)
  Y.An, K.Kato, M.Nakano, H.Otsu, S.Okada, K.Yamanaka
- Journal Title
  
  Cancer Letters (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572114
[Journal Article] The Role of trivalent dimethylated arsenic in dimethylarsinic acid-promoted skin and lung tumorigenesis in mice : Tumor promoting action through the induction of oxidative stress2005
- Author(s)
  M.Mizoi, F.Takabayashi, M.Nakano, Y.An, Y.Sagesaka, K.Kato, S.Okada, K.Yamanaka
- Journal Title
  
  Toxicology Letters (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572114
[Journal Article] The Role of trivalent dimethylated arsenic in dimethylarsinic acid-promoted skin and lung tumorigenesis in mice : Tumor promoting action through the induction of oxidative stress.2005
- Author(s)
  M.Mizoi, F.Takabayashi, M.Nakano, Y.An, Y.Sagesaka, K.Kato, S.Okada, K.Yamanaka
- Journal Title
  
  Toxicology Letters (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572114
[Journal Article] Immunohistochemical analysis of oxidative DNA damage in arsenic-related human skin samples from arsenic-contaminated area of China.2004
- Author(s)
  Y.An, Z.Gao, Z.Wang, S Yang, J.Liang, Y.Feng, K.Kato, M.Nakano, S.Okada, K.Yamanaka
- Journal Title
  
  Cancer Letters 214
  
  Pages: 11-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572114
[Journal Article] The role of active arsenic species produced by metabolic reduction of dimethylarsinic acid in genotoxicity and tumorigenesis.2004
- Author(s)
  K.Yamanaka, K.Kato, M.Mizoi, Y.An, F.Takabayashi, M.Nakano, M.Hoshino, S.Okada
- Journal Title
  
  Toxicology and Applied Pharmacology 198
  
  Pages: 385-393
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572114
[Journal Article] The role of active arsenic species produced by metabolic reduction of dimethylarsinic acid in genotoxicity and tumorigenesis.2004
- Author(s)
  K.Yamanaka, K.Kato, M.Mizoi, Y.An, F.Takabayashi, M.Nakano, M.Hoshino, S.Okada
- Journal Title
  
  Toxicology and Applied Pharmacology 198(3)
  
  Pages: 385-393
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572114
[Journal Article] Immunohistochemical analysis of oxidative DNA damage in arsenic-related human skin samples from arsenic-contaminated area of China.2004
- Author(s)
  Y.An, Z.Gao, Z.Wang, S.Yang, J.Liang, Y.Feng, K.Kato, M.Nakano, S.Okada, K.Yamanaka
- Journal Title
  
  Cancer Letters 214(1)
  
  Pages: 11-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572114
[Journal Article] Active arsenic species produced by GSH-dependent reduction of dimethylarsinic acid cause micronuclei formation in peripheral reticulocytes of mice.2003
- Author(s)
  Koichi Kato, K.Yamanaka, A.Hasegawa, S.Okada
- Journal Title
  
  Mutation Research 539
  
  Pages: 55-63
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572114
[Presentation] ジメチルモノチオアルシン酸のCaspase-8を介したアポトーシスの誘発2017
- Author(s)
  下田康代, 黒澤英俊, 加藤孝一, 畑明寿, 圓藤陽子, 圓藤吟史, 山中健三
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター宮城・仙台
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-26460176
[Presentation] ジメチルチオヒ素化合物の毒性発現におけるグルタチオンの役割2016
- Author(s)
  下田康代, 黒澤英俊, 加藤孝一, 畑明寿, 圓藤陽子, 圓藤吟史, 山中健三
- Organizer
  第22回ヒ素シンポジウム
- Place of Presentation
  国立研究開発法人産業技術総合研究所・臨海副都心センター別館東京・江東
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-26460176
[Presentation] ヒト肝細胞株HepaRGを用いたジメチルヒ素化合物の細胞毒性評価2015
- Author(s)
  下田康代、黒澤英俊、加藤孝一、立川眞理子、畑　明寿、圓藤陽子、圓藤吟史、山中健三
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫・神戸）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26460176
[Presentation] ジメチルチオアルシン酸の毒性発現に係る代謝機構について2012
- Author(s)
  山中健三、下田康代、星井政志、加藤孝一、立川眞理子、畑明寿、圓藤陽子、圓藤吟史
- Organizer
  日本薬学会132年会
- Place of Presentation
  札幌市、北海道大学
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-22590123
[Presentation] グルタチオンに依存したジメチルモノチオアルシン酸の代謝活性化2012
- Author(s)
  黒澤英俊、下田康代、畑明寿、山野優子、加藤孝一、立川眞理子、圓藤陽子、圓藤吟史、山中健三
- Organizer
  第18回ヒ素シンポジウム
- Place of Presentation
  宮崎県宮崎市、宮日ホール
- Year and Date
  2012-11-24
- Data Source
  KAKENHI-PROJECT-22590123
[Presentation] ジメチルチオアルシン酸の毒性発現に係る代謝機構について2012
- Author(s)
  山中健三、下田康代、星井政志、加藤孝一、立川眞理子、畑明寿、圓藤陽子、圓藤吟史
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-22590123
[Presentation] 含硫メチル化ヒ素の酵素的生成とその動態に関するin vitro実験での検討2011
- Author(s)
  下田康代、山中健三、加藤孝一、立川眞理子、圓藤陽子、圓藤吟史
- Organizer
  第16回ヒ素シンポジウム
- Place of Presentation
  サンアザレア(旭川)
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-22590123
[Presentation] ジメチルチオヒ素化合物の毒性発現に係わる未知ヒ素代謝物について2011
- Author(s)
  下田康代、加藤孝一、立川眞理子、圓藤陽子、圓藤吟史、山中健三
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22590123
[Presentation] ジメチルチオヒ素化合物の毒性発現に係わる未知ヒ素代謝物について2011
- Author(s)
  下田康代、加藤孝一、立川眞理子、圓藤陽子、圓藤吟史、山中健三
- Organizer
  日本薬学会第131年会
- Place of Presentation
  日本薬学会第131年会要旨集誌上において
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22590123
[Presentation] マウス大腸がんpromotionにおける炎症細胞由来の多様な活性種の寄与2009
- Author(s)
  西山耕太郎, 加藤孝一, 立川眞理子, 山中健三
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都国際会議場
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20651015
[Presentation] ジメチルアルシン酸のマウス肺発癌性の検討-鉄イオンとの相互作用2009
- Author(s)
  溝井睦美、加藤孝一、山中健三
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19590126
[Presentation] マウス潰瘍性大腸炎の増悪作用における活性炭投与の影響2008
- Author(s)
  浦野敦, 西山耕太郎, 加藤孝一, 立川眞理子, 真坂亙, 山中健三
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-20651015
[Presentation] クロラミンの大腸内生成にともなう大腸癌promotionの増強作用2008
- Author(s)
  西山耕太郎, 加藤孝一, 浦野敦, 溝井睦美, 中野雅行, 真坂亙, 立川眞理子, 山中健三
- Organizer
  フォーラム2008衛生薬学・環境トキシコロジー
- Place of Presentation
  熊本市国際交流会館
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-20651015
[Presentation] ジメチルヒ素のマウス肺発癌promotionに対する鉄暴露の増強作用2007
- Author(s)
  溝井睦美、下田康代、中野雅行、加藤孝一、山中健三
- Organizer
  第13回ヒ素シンポジウム
- Place of Presentation
  静岡
- Year and Date
  2007-11-23
- Data Source
  KAKENHI-PROJECT-19590126
[Presentation] ジメチルヒ素のマウス肺発癌 promotion に対する鉄暴露の増強作用2007
- Author(s)
  溝井睦美、加藤孝一、山中健三
- Organizer
  第13回ヒ素シンポジウム
- Place of Presentation
  静岡
- Year and Date
  2007-11-23
- Data Source
  KAKENHI-PROJECT-19590126
[Presentation] 3価ジメチルヒ素によるマウス肺発癌プロモーションにおける鉄投与の影響2007
- Author(s)
  溝井睦美、加藤孝一、山中健三
- Organizer
  第18回日本微量元素学会
- Place of Presentation
  福井
- Year and Date
  2007-07-05
- Data Source
  KAKENHI-PROJECT-19590126

1. YAMANAKA Kenzo (50182572)

# of Collaborated Projects: 8 results

# of Collaborated Products: 27 results
2. ENDO Ginji (20160393)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. SHIMODA Yasuyo (70779420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. MIZOI Mutsumi (60366630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 井上嘉則 (90382225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 圓藤陽子 (50193438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 立川眞理子 (90139098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 畑明寿 (10433690)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 市原学 (90252238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HOSHINO Mikio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKANO Masayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 立川真理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

KATO Kouichi 加藤 孝一

加藤 孝一 カトウ コウイチ

KATO Koichi 加藤 孝一

Research Projects

Research Products

Co-Researchers

Metallomic analysis to elucidate the metabolism and biological effects of arsenic compounds contained in Seafood

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the ultimate carcinogen associated with occupational cholangiocarcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Possible metabolic activation of arsenic carcinogenesis ?New mode of activation of dimethylarsenic involved with sulfur atom-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

難治性消化器疾患に関わる新規食生活要因の提言およびその病因論的考察Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Relationship between active arsenc species and tissues specificity in arsenic carcinogenesisq

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

微量金属の高精度分析法の開発:元素選択捕捉機能をもった樹脂の応用展開

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Determination of ultimate substances on arsenic carcinogenesis and in vivo formation mechanisms of their substances

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of active arsenic species produced by metabolic reduction of dimethylarsinic acid in genotoxicity and tumorigenesis : The contribution of dimethylarsenic radicals and dimethylarsenic peroxide

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A novel metabolic activation associated with glutathione in dimethylmonothioarsinic acid (DMMTAV)-induced toxicity obtained from in vitro reaction of DMMTAV with glutathione2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ingestion of Hijiki sea weed and risk of arsenic poisoning.2006

Author(s)

Journal Title

Data Source

[Journal Article] Specific induction of oxidative stress in terminal bronchiolar Clara cells during dimethylarsenic-induced lung tumor promoting process in mice.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Specific induction of oxidative stress in terminal bronchiolar Clara cells during dimethylarsenic-induced lung tumor promoting process in mice.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] The Role of trivalent dimethylated arsenic in dimethylarsinic acid-promoted skin and lung tumorigenesis in mice : Tumor promoting action through the induction of oxidative stress2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] The Role of trivalent dimethylated arsenic in dimethylarsinic acid-promoted skin and lung tumorigenesis in mice : Tumor promoting action through the induction of oxidative stress.2005

Author(s)

KATO Kouichi 加藤孝一

加藤孝一カトウコウイチ

KATO Koichi 加藤孝一