OHASHI Koji 大橋鉱二

… Alternative Names

大橋鉱二オオハシコウジ

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Researcher Number	60278281
Other IDs
Affiliation (Current)	2025: 藤田医科大学, 保健学研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 藤田医科大学, 保健学研究科, 教授 2018 – 2019: 藤田医科大学, 保健学研究科, 教授 2015 – 2017: 藤田保健衛生大学, 保健学研究科, 教授 2015: 藤田保健衛生大学, 大学院保健学研究科, 教授 2014: 藤田保健衛生大学, 医療科学部, 教授 2013: 藤田保健衛生大学, 医療科学部, 准教授
Review Section/Research Field	Principal Investigator Food science / Basic Section 38050:Food sciences-related Except Principal Investigator Laboratory medicine
Keywords	Principal Investigator 栄養 / フルクトース / インスリン抵抗性 / DOHaD / メチル化 / DNAメチル化 / エピジェネティクス / フィトケミカル / 分子栄養学 / micro RNA … More / メタボリックシンドローム / 果糖 / 次世代に対する影響 / 脱共役蛋白 / 海馬 … More Except Principal Investigator バイオマーカー / 非アルコール性脂肪肝（NAFLD） / マイクロRNA（miRNA） / マイクロRNA（miRNA) / スクリーニング検査法 / 非アルコール性脂肪肝(NAFLD) / マイクロRNA(miRNA) / NAFLD / microRNA / 血清miRNA / miR-122 / 血清mi-RNA-１２２ / 非アルコール性脂肪肝 / 臨床検査 / 血清miR-122 Less

食成分に着目したDOHaDの予防法の確立：エピジェネティック作用によるアプローチPrincipal Investigator
- Principal Investigator
  
  大橋鉱二
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Fujita Health University
Association of maternal fructose intake and offspring insulin resistancePrincipal Investigator
- Principal Investigator
  
  Ohashi Koji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Fujita Health University
A circulating microRNA signature as noninvasive biomarkers for NAFLD
- Principal Investigator
  
  Teradaira Ryoji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fujita Health University
Effect of maternal excess fructose consumption on the offspringPrincipal Investigator
- Principal Investigator
  
  OHASI Koji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Fujita Health University
Evaluation of serum micro-RNA as a new biomarker for non-alcoholic fatty liver disease (NAFLD)
- Principal Investigator
  
  TERADAIRA Ryoji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Fujita Health University

All 2023 2022 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] Epigenetics and fructose metabolism: A new mechanism of fructose effects2019
- Author(s)
  Munetsuna, E., Yamazaki, M., Ohashi, K., Yamada, H.
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-17K07805
[Book] High-fructose consumption and the epigenetics of DNA methylation2019
- Author(s)
  Yamada, H., Munetsuna, E., Ohashi, K.
- Publisher
  SprikkerLink
- Data Source
  KAKENHI-PROJECT-17K07805
[Journal Article] High-fructose corn syrup intake increases hepatic mitochondrial DNA copy number and methylation in adolescent rats2023
- Author(s)
  Mizuno Genki、Yamada Hiroya、Munetsuna Eiji、Ando Yoshitaka、Teshigawara Atsushi、Ito Manaka、Kageyama Itsuki、Nouchi Yuki、Wakasugi Takuya、Sakakibara Tomohide、Yamazaki Mirai、Ishikawa Hiroaki、Suzuki Koji、Hashimoto Shuji、Ohashi Koji
- Journal Title
  
  Nutrition Research
  
  Volume: 110 Pages: 57-65
- DOI
  10.1016/j.nutres.2022.12.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05483, KAKENHI-PROJECT-22K10494, KAKENHI-PROJECT-20H04134
[Journal Article] Effects of High-Fructose Corn Syrup Intake on Glucocorticoid Metabolism in Rats During Childhood, Adolescence and Adulthood2022
- Author(s)
  Nouchi Yuki、Munetsuna Eiji、Yamada Hiroya、Yamazaki Mirai、Ando Yoshitaka、Mizuno Genki、Fujii Ryosuke、Kageyama Itsuki、Wakasugi Takuya、Sakakibara Tomohide、Teshigawara Atsushi、Ishikawa Hiroaki、Shimono Yohei、Suzuki Koji、Hashimoto Shuji、Ohashi Koji
- Journal Title
  
  Experimental and Clinical Endocrinology & Diabetes
  
  Volume: 130 Issue: 12 Pages: 814-820
- DOI
  10.1055/a-1936-3310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05483, KAKENHI-PROJECT-22K10494, KAKENHI-PROJECT-20H04134
[Journal Article] Differential effects of excess high-fructose corn syrup on the DNA methylation of hippocampal neurotrophic factor in childhood and adolescence2022
- Author(s)
  Kageyama Itsuki、Yamada Hiroya、Munetsuna Eiji、Yamazaki Mirai、Ando Yoshitaka、Mizuno Genki、Fujii Ryosuke、Nouchi Yuki、Wakasugi Takuya、Sakakibara Tomohide、Teshigawara Atsushi、Ishikawa Hiroaki、Shimono Yohei、Suzuki Koji、Hashimoto Shuji、Ohashi Koji
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 6 Pages: e0270144-e0270144
- DOI
  10.1371/journal.pone.0270144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05483, KAKENHI-PROJECT-22K10494, KAKENHI-PROJECT-20H04134
[Journal Article] Maternal fructose consumption down-regulates Lxra expression via miR-206-mediated regulation.2020
- Author(s)
  Yamazaki M, Munetsuna E, Yamada H, Ando Y, Mizuno G, Fujii R, Nouchi Y, Kageyama I, Teshigawara A, Ishikawa H, Suzuki K, Shimono Y, Hashimoto S, Ohashi K.
- Journal Title
  
  J Nutr Biochem
  
  Volume: 14 Pages: 108386-108386
- DOI
  10.1016/j.jnutbio.2020.108386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07805, KAKENHI-PROJECT-20H04134, KAKENHI-PROJECT-18K05493
[Journal Article] Maternal high-fructose intake increases circulating corticosterone levels via decreased adrenal corticosterone clearance in adult offspring.2019
- Author(s)
  Munetsuna E, Yamada H, Yamazaki M, Ando Y, Mizuno G, Hattori Y, Sadamoto N, Ishikawa H, Ohta Y, Fujii R, Suzuki K, Hashimoto S, Ohashi K
- Journal Title
  
  Journal of nutritional biochemistry
  
  Volume: 67 Pages: 44-50
- DOI
  10.1016/j.jnutbio.2019.01.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07805, KAKENHI-PROJECT-18K05493, KAKENHI-PROJECT-18K17987
[Journal Article] Maternal fructose-induced oxidative stress occurs via Tfam and Ucp5 epigenetic regulation in offspring hippocampi.2019
- Author(s)
  Yamada H, Munetsuna E, Yamazaki M, Mizuno G, Sadamoto N, Ando Y, Fujii R, Shiogama K, Ishikawa H, Suzuki K, Shimono Y, Ohashi K, Hashimoto S
- Journal Title
  
  FASEB journao
  
  Volume: 33 Issue: 10 Pages: 11431-11442
- DOI
  10.1096/fj.201901072r
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05493, KAKENHI-PROJECT-17K07805, KAKENHI-PROJECT-18K17987
[Journal Article] Maternal fructose intake disturbs ovarian estradiol synthesis in rats2018
- Author(s)
  Munetsuna E, Yamada H, Yamazaki M, Ando Y, Mizuno G, Ota T, Hattori Y, Sadamoto N, Suzuki K, Ishikawa H, Hashimoto S, Ohashi K.
- Journal Title
  
  Life Sciences
  
  Volume: 印刷中 Pages: 1231-1239
- DOI
  10.1016/j.lfs.2018.04.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07805, KAKENHI-PROJECT-18K05493, KAKENHI-PROJECT-18K17987
[Journal Article] Fructose intake during gestation and lactation differentially affects the expression of hippocampal neurosteroidogenic enzymes in rat offspring2017
- Author(s)
  Genki Mizuno, Eiji Munetsuna, Hiroya Yamada, Yoshitaka Ando, Mirai Yamazaki1, Yuri Murase, Kanako Kondo, Hiroaki Ishikawa, Ryoji Teradaira, Koji Suzuki, Koji Ohashi
- Journal Title
  
  Endocrine Research
  
  Volume: 42 Issue: 1 Pages: 71-77
- DOI
  10.1080/07435800.2016.1182186
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26450169
[Journal Article] Stability of serum high-density lipoprotein-microRNAs for preanalytical conditions.2017
- Author(s)
  Ishikawa H, Yamada H, Taromaru N, Kondo K, Nagura A, Yamazaki M, Ando Y, Munetsuna E, Suzuki K, Ohashi K, Teradaira R.
- Journal Title
  
  Ann Clin Biochem
  
  Volume: 54 Issue: 1 Pages: 134-142
- DOI
  10.1177/0004563216647086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860375, KAKENHI-PROJECT-16K08946
[Journal Article] Fructose consumption induces hypomethylation of hepatic mitochondrial DNA in rats2016
- Author(s)
  Mirai Yamazak, Eiji Munetsuna, Hiroya Yamada, Yoshitaka Ando, Genki Mizuno, Yuri Murase, Kanako Kndo, Hiroaki Ishikawa, Ryoji Teradaira, Koji Suzuki, Koji Ohashi
- Journal Title
  
  Life Sciences
  
  Volume: 149 Pages: 146-152
- DOI
  10.1016/j.lfs.2016.02.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460706
[Journal Article] Fructose intake during gestation and lactation differentially affects the expression of hippocampal neurosteroidogenic enzymes in rat offspring2016
- Author(s)
  Genki Mizuno, Eiji Munetsuna, Hiroya Yamada, Yoshitaka Ando, Mirai Yamazaki1, Yuri Murase, Kanako Kondo, Hiroaki Ishikawa, Ryoji Teradaira, Koji Suzuki, Koji Ohashi,
- Journal Title
  
  Endocrine Research
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450169
[Journal Article] High fructose consumption induces DNA methylation at PPARα and CPT1A promoter regions in the rat liver2015
- Author(s)
  Koji Ohashi, Eiji Munetsuna, Hiroya Yamada, Yoshitaka Ando, Mirai Yamazaki, Nao Taromaru, Ayuri Nagura, Hiroaki Ishikawa, Koji Suzuki, Ryoji Teradaira, Shuji Hashimoto
- Journal Title
  
  Biochemical and Biophysical Research Cmmunications
  
  Volume: 468 Issue: 1-2 Pages: 185-189
- DOI
  10.1016/j.bbrc.2015.10.134
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460706
[Journal Article] Maternal fructose consumption alters messenger RNA expression of hippocampal StAR, PBR, P450(11β), 11β-HSD, and 17β-HSD in rat offspring2015
- Author(s)
  Koji　Ohashi,　Yoshitaka Ando, Eiji Munetsuna, Hiroya Yamada, Mirai Yamazaki, Ayuri Nagura, Nao Taromaru, Hiroaki Ishikawa, Koji Suzuki, Ryouji Teradaira
- Journal Title
  
  Nutrition research
  
  Volume: 35 Issue: 3 Pages: 259-264
- DOI
  10.1016/j.nutres.2014.11.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26450169, KAKENHI-PROJECT-25460706
[Presentation] 母獣のHFCS過剰摂取は仔の肝脂質代謝関連遺伝子の高メチル化を誘導する2023
- Author(s)
  安藤嘉崇、山田宏哉、宗綱栄二、山崎未来、景山斎、野内佑起、藤井亮輔、水野元貴、石川浩章、鈴木康司、大橋鉱二
- Organizer
  第96回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K05483
[Presentation] 妊娠期のフルクトース過剰摂取が次世代の海馬神経幹細胞に及ぼす影響2023
- Author(s)
  景山斎、山田宏哉、宗綱栄二、大城雅貴、若杉拓哉、伊藤愛佳、野内佑起、波田薫平、山崎未来、水野元貴、安藤嘉崇、石川浩章、鈴木康司、大橋鉱二
- Organizer
  第96回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K05483
[Presentation] フルクトース過剰摂取モデルラットの肝オルガノイド作成と評価2022
- Author(s)
  市川勇斗、山田宏哉、宗綱栄二、安藤嘉崇、景山斎、野内佑起、池谷美幸、波田薫平、山崎未来、水野元貴、石川浩章、鈴木康司、大橋鉱二
- Organizer
  第93回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-22K05483
[Presentation] 母獣のHFCS過剰摂取が仔の肝遺伝子発現に及ぼす影響2022
- Author(s)
  安藤嘉崇、山田宏哉、宗綱栄二、山崎未来、景山斎、野内佑起、藤井亮輔、水野元貴、石川浩章、鈴木康司、大橋鉱二
- Organizer
  第95回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K05483
[Presentation] Maternal fructose consumption during gestation and lactation downregulated Igf-1 expression in offspring rat2019
- Author(s)
  Yoshitaka Ando, Hiroya Yamada, Yuji Hattori, Mirai Yamazaki, Eiji Munetsuna, Hiroaki Ishikawa, Genki Mizuno, Yuri Murase, Nao Sadamoto, Daiki Shimodaira, Ryoji Teradaira, Koji Ohashi
- Organizer
  国際DOHaD学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07805
[Presentation] Excess maternal fructose consumption affects estradiol synthesis in rat offspring2019
- Author(s)
  Eiji Munetsuna, Hiroya Yamada, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Yuji Hattori, Nao Sadamoto, Koji Suzuki, Hiroaki Ishikawa, Shuji Hashimoto, Koji Ohashi
- Organizer
  国際DOHaD学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07805
[Presentation] 母獣のHigh Fructose Corn Syrup過剰摂取が仔の糖・脂質代謝に与える影響2019
- Author(s)
  貞本奈緒、山田宏哉、宗綱栄二、安藤嘉崇、山崎未来、水野元貴、下平大輝、勅使河原篤志、影山斎、野内佑起、石川浩章、大橋鉱二
- Organizer
  日本DOHaD学会
- Data Source
  KAKENHI-PROJECT-17K07805
[Presentation] 母獣のフルクトース過剰摂取が仔海馬の脳由来神経栄養因子の発現に及ぼす影響2018
- Author(s)
  山崎未来, 山田宏哉, 宗綱栄二, 水野元貴, 鈴木康司, 石川浩章, 橋本修二, 大橋鉱二
- Organizer
  第91回日本内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K07805
[Presentation] 母獣のフルクトース過剰摂取が次世代のエストロゲン合成に及ぼす影響2018
- Author(s)
  宗綱栄二, 山田宏哉, 山崎未来, 水野元貴, 太田駿瑠, 石川浩章, 鈴木康司, 大橋鉱二
- Organizer
  第91回日本内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K07805
[Presentation] 母獣のフルクトース過剰摂取が仔海馬 Uncoupling Proteins 発現に与える影響2018
- Author(s)
  貞本奈緒、水野元貴、山田宏哉、宗綱栄二、山崎未来、服部裕次、下平大輝、安藤嘉崇、石川浩章、鈴木康司、大橋鉱二
- Organizer
  日本DOHaD研究会
- Data Source
  KAKENHI-PROJECT-17K07805
[Presentation] 母獣のフルクトース過剰摂取が次世代のエストロゲン合成に及ぼす影響2018
- Author(s)
  宗綱栄二, 山田宏哉, 山崎未来, 水野元貴, 太田駿瑠, 石川浩章, 鈴木康司, 大橋鉱二
- Organizer
  日本内分泌学会
- Data Source
  KAKENHI-PROJECT-17K07805
[Presentation] 非アルコール性脂肪性肝疾患における新規バイオマーカーとしての血清miR-122/miR-27a比の検討2017
- Author(s)
  山崎未来、山田宏哉、宗綱栄二、安藤嘉崇、石川浩章、寺平良治、大橋鉱二
- Organizer
  第57回日本臨床化学会年次学術集会、北海道大学、札幌市
- Data Source
  KAKENHI-PROJECT-16K08946
[Presentation] High Fructose Consumption Induces Hypomethylation of Hepatic Mitochondrial DNA in Rats2016
- Author(s)
  Mirai Yamazaki, Eiji Munetsuna, Hiroya Yamada, Yoshitaka Ando, Genki Mizuno, Yuri Murase, Kanako Kondo, Takeru Ota, Hiroaki Ishikawa, Ryoji Teradaira, Koji Suzuki, Koji Ohashi
- Organizer
  14th Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-11-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08946
[Presentation] 妊娠授乳期のフルクトース過剰摂取が仔のインスリン抵抗性へ及ぼす影響2016
- Author(s)
  村瀬悠理、水野元貴、山崎未来、近藤奏子、山田宏哉、宗綱栄二、石川浩章、寺平良治、鈴木康司、大橋鉱二
- Organizer
  第26回生物試料分析科学会年次学術集会
- Place of Presentation
  沖縄コンベンションセンター会議棟
- Year and Date
  2016-02-20
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] 妊娠授乳期フルクトース過剰摂取モデルにおける仔の海馬酸化ストレス状態の解析2016
- Author(s)
  水野元貴、村瀬悠理、山崎未来、近藤奏子、太田駿瑠、山田宏哉、宗綱栄二、石川浩章、寺平良治、鈴木康司、大橋鉱二
- Organizer
  第63回日本臨床検査医学会学術集会
- Place of Presentation
  神戸(神戸国際会議場)
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-26450169
[Presentation] Maternal Fructose Consumption Alters Gene Expression Involved in Hepatic Glucocorticoid Metabolism in Rat Offspring2016
- Author(s)
  Yuri Murase, Eiji Munetsuna, Hiroya Yamada, Mirai Yamazaki, Genki Mizuno, Kanako Kondo, Takeru Ota, Hiroaki Ishikawa, Ryoji Teradaira, Koji Suzuki, Koji Ohashi
- Organizer
  14th Asis-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress (APFCB 2016)
- Place of Presentation
  Taipei, TAIWAN（Taipei International Center)
- Year and Date
  2016-11-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450169
[Presentation] The Establishment of Simpler Method for Measuring HDL-MiRNAs2016
- Author(s)
  Kanako Kondo, Hiroaki Ishikawa, Hiroya Yamada, Mirai Yamazaki, Yuri Murase, Genki Mizuno, Takeru Ota, Eiji Munetsuna, Koji Suzuki, Ryoji Teradaira, Koji Ohashi
- Organizer
  14th Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-11-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08946
[Presentation] Basic Study on DNA Methylation Analysis - Targeting Promoter Region of Cytokine Genes in Human Whole Blood2016
- Author(s)
  Genki Mizuno, Hiroya Yamada, Mirai Yamazaki, Takeru Ota, Yuri Murase, Kanako Kondo, Eiji Munetsuna, Hiroaki Ishikawa, Koji Ohashi, Koji Suzuki
- Organizer
  14th Asis-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress (APFCB 2016)
- Place of Presentation
  Taipei, TAIWAN（Taipei International Center)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450169
[Presentation] 母獣のフルクトース過剰摂取が仔のコルチコステロン代謝に及ぼす影響2016
- Author(s)
  村瀬悠理、宗綱栄二、山田宏哉、山崎未来、水野元貴、近藤奏子、太田駿瑠、石川浩章、寺平良治、鈴木康司、大橋鉱二
- Organizer
  第56回日本臨床化学会年次学術集会
- Place of Presentation
  熊本（くまもと県民交流館パレア）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26450169
[Presentation] 血中HDL-miRNA測定法の確立2016
- Author(s)
  近藤奏子、石川浩章、山崎未来、村瀬悠理、水野元貴、太田駿瑠、山田宏哉、宗綱栄二、鈴木康司、寺平良治、大橋鉱二
- Organizer
  第63回日本臨床検査医学会学術集会
- Place of Presentation
  神戸(神戸国際会議場)
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-26450169
[Presentation] 妊娠授乳期のフルクトース過剰摂取における仔の海馬Ucp発現解析2016
- Author(s)
  水野元貴、村瀬悠理、山崎未来、近藤奏子、山田宏哉、宗綱栄二、石川浩章、寺平良治、鈴木康司、大橋鉱二
- Organizer
  第26回生物試料分析科学会年次学術集会
- Place of Presentation
  沖縄コンベンションセンター会議棟
- Year and Date
  2016-02-20
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] The establishment of simpler method for measuring HDL-miRNAs2016
- Author(s)
  Kanako Kondo, Hiroaki Ishikawa, Hiroya Yamada, Mirai Yamazaki, Yuri Murase, Genki Mizuno, Takeru Ota, Eiji Munetsuna, Koji Suzuki, Ryoji Teradaira, Koji Ohashi
- Organizer
  14th Asis-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress (APFCB 2016)
- Place of Presentation
  Taipei, TAIWAN（Taipei International Center)
- Year and Date
  2016-11-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450169
[Presentation] Maternal Fructose Consumption Alters Gene Expression Involved in Hepatic Glucocorticoid Metabolism in Rat Offspring2016
- Author(s)
  Yuri Murase, Eiji Munetsuna, Hiroya Yamada, Mirai Yamazaki, Genki Mizuno, Kanako Kondo, Takeru Ota, Hiroaki Ishikawa, Ryoji Teradaira, Koji Suzuki, Koji Ohashi
- Organizer
  14th Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine Congress
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-11-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08946
[Presentation] 非アルコール性脂肪性肝疾患モデル動物におけるmiR-20a、miR27aの経時的変化2016
- Author(s)
  山崎未来、山田宏哉、安藤嘉崇、近藤奏子、水野元貴、村瀬悠理、太田駿瑠、石川浩章、宗綱栄二、鈴木康司、大橋鉱二
- Organizer
  第56回日本臨床化学会年次学術集会
- Place of Presentation
  熊本（くまもと県民交流館パレア）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26450169
[Presentation] High fructose consumption alters DNA metylation in rat liver.2015
- Author(s)
  Koji Ohashi, Hiroya Yamada, Yoshitaka Ando, Eiji Munetsuna, Mirai Yamazaki, Genki Mizuno, Kanako Kondo, Hiroaki Ishikawa, Koji Suzuki, Ryoji Teradaira
- Organizer
  IFCC-EFLM Euromedlab Paris 2015 congress
- Place of Presentation
  Paris
- Year and Date
  2015-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] Serum levels of miR-20a and miR-27a are associated with NAFLD in a general Japanese population: the Yakumo study2015
- Author(s)
  Mirai Yamazaki, Koji Suzuki, Hiroya Yamada, Koji Ohashi, Naohiro Ichino, Hiroaki Ishikawa, Keisuke Osakabe, Keiko Sugimoto, Eiji Munetsuna, Genki Mizuno, Kanako Kondo, Takashi Inoue, Ryoji Teradaira
- Organizer
  IFCC-EFLM Euromedlab Paris 2015 Congress
- Place of Presentation
  Ｐａｒｉｓ
- Year and Date
  2015-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] Stability of HDL-miRNA for pre-analytical conditions-2015
- Author(s)
  Hiroaki Ishikawa, Nao Taromaru, Kanako Kondo, Mirai Yamazaki, Genki Mizuno, Hiroya Yamada, Koji Suzuki, Eiji Munetsuna, Koji Ohashi1, Ryoji Teradaira
- Organizer
  21st IFCC-EFLM (European Congress of Clinical Chemistry and Laboratory Medicine) EUROLAB PARIS 2015
- Place of Presentation
  Paris, France
- Year and Date
  2015-06-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450169
[Presentation] Stability of HDL-miRNA for pre-analytical conditions - Effect of RNase on HDL-miRNA -2015
- Author(s)
  Hiroaki Ishikawa, Nao Taromaru, Kanako Kondo, Mirai Yamazaki, Genki Mizuno, Hiroya Yamada, Koji Suzuki, Eiji Munetsuna, Koji Ohashi, Ryoji Teradaira
- Organizer
  IFCC-EFLM Euromedlab Paris 2015 congress
- Place of Presentation
  Paris
- Year and Date
  2015-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] Serum levels of miR-20a and miR-27a are associated with NAFLD in a general Japanese population: the Yakumo Study.2015
- Author(s)
  Mitai Yamazaki, Koji Suzuki, Hiroya Yamada, Koji Ohashi, Naohiro Ichino, Hiroaki Ishikawa, Keisuke Osakabe, Keiko Sugimoto, Eiji Munetsuna, Genki Mizuno, Kanako Kondo, Takashi Inoue, Ryoji Teradaira
- Organizer
  21st IFCC-EFLM (European Congress of Clinical Chemistry and Laboratory Medicine) EUROLAB PARIS 2015
- Place of Presentation
  Paris, France
- Year and Date
  2015-06-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450169
[Presentation] High fructose consumption alters DNA methylation in rat liver.2015
- Author(s)
  Koji Ohashi, Hiroya Yamada, Yoshitaka Ando, Eiji Munetsuna, Mitai Yamazaki, Genki Mizuno, Kanako Kondo, Hiroaki Ishikawa, Koji Suzuki, Ryoji Teradaira
- Organizer
  21st IFCC-EFLM (European Congress of Clinical Chemistry and Laboratory Medicine) EUROLAB PARIS 2015
- Place of Presentation
  Paris, France
- Year and Date
  2015-06-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450169
[Presentation] メタボリックシンドロームで変動する血清microRNAと喫煙習慣の関連2014
- Author(s)
  名倉鮎里、大橋鉱二、山田宏哉、石川浩章、鈴木康司、市野直浩、安藤嘉崇、太郎丸奈央、山崎未来、井上孝、寺平良治
- Organizer
  第25回日本臨床化学会東海・北陸支部総会、第33回臨床検査医学会東海北陸支部例会連合大会
- Place of Presentation
  名古屋大学
- Year and Date
  2014-08-02
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] Assessment of serum miR-122 as novel biomarker for on-alcoholic fatty liver disease in rat model2013
- Author(s)
  Akira Sawada, Koji Ohashi, Hiroya Yamada, Yoshitaka Ando, Hiroaki Ishikawa, Koji Suzuki, Naohiro Ichino, Ryoji Teradaira
- Organizer
  13th APFCB
- Place of Presentation
  Bali
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] Association of serum miR-122 levels with BMI, visceral and subcutaneous fat.2013
- Author(s)
  Ohashi K, Yamada H, Suzuki K, Ichino N, Ando Y, Sawada A, Ishikawa H, Teradaira R, Hashimoto S
- Organizer
  13th APFCB
- Place of Presentation
  Bali
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] 血清miR-122は肥満指標と関連する2013
- Author(s)
  山田宏哉、鈴木康司、市野直浩、安藤嘉崇、沢田章、石川浩章、大橋鉱二、寺平良治、井上孝、橋本修二
- Organizer
  第60回日本臨床検査医学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] 非アルコール性脂肪肝モデルラットにおける血清microRNAの変化2013
- Author(s)
  沢田章、山田宏哉、大橋鉱二、安藤嘉崇、太郎丸奈央、石川浩章、鈴木康司、市野直浩、寺平良治
- Organizer
  第53回日本臨床化学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] Serum miR-122 as potential biomarker for non-alcoholic fatty liver2013
- Author(s)
  Hiroya Yamada, Koji Suzuki, Naohiro Ichino, Ando Yoshitaka, Sawada Akira, Keisuke Osakabe, Keiko Sugimoto, Ohashi Koji, Teradaira Ryouji, Takashi Inoue, Nobuyuki Hamajima, Shuji Hashimoto
- Organizer
  13th APFCB
- Place of Presentation
  Bali
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] Analysis of the circulating HDL-miRNA stability for pre-analytical conditions
- Author(s)
  Nao Taromaru, Hiroaki Ishikawa, Yoshitaka Ando, Ayuri Nagura, Mirai Yamazaki, Hiroya Yamada, Koji Suzuki, Koji Ohashi, Ryoji Teradaira
- Organizer
  22nd International Congress of Clinical Chemistry and Laboratory Medicine
- Place of Presentation
  ＩｓｔａｎｂｕｌｅＣｏｎｇｒｅｓｓＣｅｎｔｅｒ，Istanbul ,Turkey
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-26450169
[Presentation] Circulating microRNAs ,miR197, let7d, miR150, miR92, is influenced by smoking status in general population.
- Author(s)
  Ayuri Nagura, Hiroya Yamada, Koji Ohashi, Hiroaki Ishikawa, Koji Suzuki, Naohiro Ichino, Yoshitaka Ando, Nao Taromaru, Mirai Yamazaki, Rika Watarai, Takashi Inoue, Nobuyuki Hamajima, Ryoji Teradaira
- Organizer
  FCC (International Federation of Clinical Chemistry and Laboratory Medicine) WorldLab Istanbul 2014
- Place of Presentation
  Istanbul, Turtey
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] Circulating microRNAs ,miR197, let7d, miR150, miR92, are influenced by smoking status in general population.
- Author(s)
  Ayuri Nagura, Hiroya Yamada, Koji Ohashi, Hiroaki Ishikawa, Koji Suzuki, Naohiro Ichino, Yoshitaka Ando, Nao Taromaru, Mirai Yamazaki, Rika Watarai, Takashi Inoue, Nobuyuki Hamajima, Ryoji Teradaira
- Organizer
  22nd International Congress of Clinical Chemistry and Laboratory Medicine
- Place of Presentation
  ＩｓｔａｎｂｕｌｅＣｏｎｇｒｅｓｓＣｅｎｔｅｒ， Istanbul ,Turkey
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-26450169
[Presentation] 住民健診受診者における血清miR-20a, miR-27a, miR-146, miR-320とNAFLDとの関連性
- Author(s)
  山崎未来、山田宏哉、安藤嘉崇、大橋鉱二、鈴木康司、市野直浩、石川浩章、名倉鮎里、太郎丸奈央、刑部恵介、杉本恵子、井上孝、寺平良治
- Organizer
  第61回日本臨床検査医学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-11-22 – 2014-11-25
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] Associations between circulating microRNAs miR-20a or miR-27a and non-alcoholic fatty liver disease in a general Japanese population: the Yakumo study.
- Author(s)
  Mirai Yamazaki, Hiroya Yamada, Yoshitaka Ando, Koji Ohashi,Koji Suzuki, Naohiro Ichino, Hiroaki Ishikawa, Nao Taromaru, Ayuri Nagura, Keisuke Osakabe, Keiko Sugimoto, Takashi Inoue, Nobuyuki Hamajima, Ryoji Teradaira
- Organizer
  IFCC (International Federation of Clinical Chemistry and Laboratory Medicine) WorldLab Istanbul 2014
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] Associations between circulating microRNAs miR-20a or miR-27a and non-alcoholic fatty liver disease in a general Japanese population: the Yakumo study.
- Author(s)
  Mirai Yamazaki, Hiroya Yamada, Yoshitaka Ando, Koji Ohashi, Koji Suzuki, Naohiro Ichino, Hiroaki Ishikawa, Nao Taromaru, Ayuri Nagura, Keisuke Osakabe, Keiko Sugimoto, Takashi Inoue, Nobuyuki Hamajima, Ryoji Teradaira
- Organizer
  22nd International Congress of Clinical Chemistry and Laboratory Medicine
- Place of Presentation
  ＩｓｔａｎｂｕｌｅＣｏｎｇｒｅｓｓＣｅｎｔｅｒ，Istanbul ,Turkey
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-26450169
[Presentation] Association of serum level of microRNAs (miR-27a, miR-122, and miR-320) with obesity index among Japanese subjects.
- Author(s)
  Yamada Hiroya, Suzuki Koji, Ichino Naohiro, Ohashi Koji, Osakabe Keisuke, Sugimoto Keiko, Ando Yoshitaka, Ishikawa Hiroaki, Teradaira Ryoji, Inoue Takashi, Hamajima Nobuyuki, Hashimoto Shuji
- Organizer
  20th IEA World Congress of Epidemiology
- Place of Presentation
  Anchorage, USA
- Year and Date
  2014-08-16 – 2014-08-21
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] 住民健診受診者における血清miR-197, miR-320, miR-150, miR-146と非アルコール性脂肪肝疾患との関連性
- Author(s)
  山崎未来、山田宏哉、大橋鉱二、安藤嘉崇、名倉鮎里、太郎丸奈央、石川浩章、寺平良治
- Organizer
  第9回日本臨床検査学教育学会
- Place of Presentation
  東京都大田区産業プラザ
- Year and Date
  2014-08-20 – 2014-08-22
- Data Source
  KAKENHI-PROJECT-25460706
[Presentation] 血清miR-197, let7d, miR-150, miR-92の動態は喫煙習慣の影響を受ける
- Author(s)
  名倉鮎里、大橋鉱二、山田宏哉、石川浩章、鈴木康司、市野直浩、安藤嘉崇、太郎丸奈央、山崎未来、井上孝、浜島信之、寺平良治
- Organizer
  第54回日本臨床化学会年次学術集会
- Place of Presentation
  東京大学
- Year and Date
  2014-09-05 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-25460706

1. 宗綱栄二 (30600431)

# of Collaborated Projects: 3 results

# of Collaborated Products: 33 results
2. TERADAIRA Ryoji (80087668)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
3. Yamada Hiroya (80610352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results

OHASHI Koji 大橋 鉱二

大橋 鉱二 オオハシ コウジ

Research Projects

Research Products

Co-Researchers

食成分に着目したDOHaDの予防法の確立：エピジェネティック作用によるアプローチPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Association of maternal fructose intake and offspring insulin resistancePrincipal Investigator

Principal Investigator

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A circulating microRNA signature as noninvasive biomarkers for NAFLD

Principal Investigator

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Effect of maternal excess fructose consumption on the offspringPrincipal Investigator

Principal Investigator

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Research Institution

Evaluation of serum micro-RNA as a new biomarker for non-alcoholic fatty liver disease (NAFLD)

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[Book] Epigenetics and fructose metabolism: A new mechanism of fructose effects2019

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[Book] High-fructose consumption and the epigenetics of DNA methylation2019

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[Journal Article] High-fructose corn syrup intake increases hepatic mitochondrial DNA copy number and methylation in adolescent rats2023

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[Journal Article] Effects of High-Fructose Corn Syrup Intake on Glucocorticoid Metabolism in Rats During Childhood, Adolescence and Adulthood2022

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[Journal Article] Differential effects of excess high-fructose corn syrup on the DNA methylation of hippocampal neurotrophic factor in childhood and adolescence2022

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[Journal Article] Maternal fructose consumption down-regulates Lxra expression via miR-206-mediated regulation.2020

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[Journal Article] Maternal high-fructose intake increases circulating corticosterone levels via decreased adrenal corticosterone clearance in adult offspring.2019

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[Journal Article] Maternal fructose-induced oxidative stress occurs via Tfam and Ucp5 epigenetic regulation in offspring hippocampi.2019

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[Journal Article] Maternal fructose intake disturbs ovarian estradiol synthesis in rats2018

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[Journal Article] Fructose intake during gestation and lactation differentially affects the expression of hippocampal neurosteroidogenic enzymes in rat offspring2017

Author(s)

OHASHI Koji 大橋鉱二

大橋鉱二オオハシコウジ