Saikawa Yutaka 犀川太

… Alternative Names

SAIKAWA Yutaka 犀川太

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Researcher Number	60283107
Other IDs
External Links
Affiliation (Current)	2022: 金沢医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2021: 金沢医科大学, 医学部, 教授 2012 – 2014: 金沢医科大学, 医学部, 教授 2010: 金沢大学, 医学系, 教授 2008 – 2010: Kanazawa Medical University, 医学部, 教授 2005 – 2007: 金沢大学, 医学部附属病院, 講師 … More 2002: Kanazawa University, Kanazawa University Hospital, Lecturer, 医学部附属病院, 講師 2001: 金沢大学, 医学部・附属病院・小児科, 講師 1997 – 2001: 金沢大学, 医学部・附属病院, 講師 Less
Review Section/Research Field	Principal Investigator Pediatrics / Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Pediatrics / Pediatrics
Keywords	Principal Investigator システム生物学 / 白血病幹細胞 / コンピューターシミュレーション / コンピュータシミュレーション / 急性骨髄性白血病 / セルラオートマトン / セルオートマトン / 血液病学 / 微小残存病変 / 白血病治療モデル … More / 白血病造血モデル / 葉酸受容体 / 組織特異的遺伝子発現 / 薬剤耐性 / 転写因子 / alpha human folate receptor gene / tissue specific expression of the gene / drug resistance / transcriptional factor / ヒトヘムオキシゲナーゼ1遺伝子 / 遺伝子欠損症 / 遺伝子修復 / Alu配列 / 相同組み換え / 部位特異的組み換え酵素 / ヒトヘムォキシゲナーゼ1遺伝子 / Human hemeoxygenase-1 / hereditary disease / gene correction / Alu repeat / homologous recombination / site-specific recombinase / 顆粒球造血 / 細胞動態解析 / Granulopoiesis / Computer simulation / Systems biology / Kinetic analysis of cellular behaviour / コンピュータ解析 / 再発 / 細胞移動軌跡 / 再発予測 / 再発予知 / 標的治療 … More Except Principal Investigator ヘムオキシゲナーゼ / 血管炎 / ヘムオキシゲナーゼ1 / 血管内皮障害 / Hemin / 単球 / HO-1 / 腎尿細管 / Vasculitis / Inflammation / ヘミン / 溶血性貧血 / 酸化ストレス / 慢性炎症 / Heme oxygenase-1 / Aluくり返し配列 / 肺高血圧症 / ストレス防御 / 遺伝病 / 炎症 / 内皮細胞 / Heme oxygenase / Endothelial injury / Oxidative stress / CD163 / Hemeoxygenase-1 / マクロファージ / 感染症 / 川崎病 / がん転移 / 血管新生 / ヘモグロビン / 骨髄移植 / 乳児白血病 / GVHD / Hemolytic anemia / Enzyme defect / Carbon monoxide / 造血系細胞 / ECV304 / 先天性心疾患 / 肺高血圧 / Monocytes / Proximal tubular epithelial cells / Alu-Alu recombination / 凝固線溶系 / CD 163 / ヘム / 炎症防御 / ヒトHO-1欠損症 / HO / Heme omenase / Coagulation / fibrinolvsis system / Monnsvts / Endothelial cell / Renal tubular enitherial cell Less

Computing analysis of leukemic stem cell dynamics in acute myelocytic leukemiaPrincipal Investigator
- Principal Investigator
  
  SAIKAWA Yutaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kanazawa Medical University
Computational leukemic stem cell models in systems biology for analyses of cell kinetics in leukemic relapse and development of risk-stratified chemotherapyPrincipal Investigator
- Principal Investigator
  
  SAIKAWA Yutaka
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa Medical University
Computational leukemic stem cell models in systems biology for predicting relapse and development of risk-stratified chemotherapyPrincipal Investigator
- Principal Investigator
  
  SAIKAWA Yutaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa Medical University
Physiological importance of heme oxygenase-1 on hemopoiesis, inflammation and immunology system
- Principal Investigator
  
  KOIZUMI Shoichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
Heme oxygenase-1 deficiency and failure of human defense mechanisms against generalized chronic inflammation
- Principal Investigator
  
  KOIZUMI Shoichi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
Kinetic analysis of minimal residual disease using 3-dimentinal computational models of human granulopoiesis and development of risk of relapse-stratified treatment of pediatric leukemia.Principal Investigator
- Principal Investigator
  
  SAIKAWA Yutaka
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
マクロファージの活性化とヘムオキシゲナーゼ1発現:癌細胞における血管新生との相関
- Principal Investigator
  
  小泉晶一
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
Multilateral-physiological and functional evidences of the heme oxygenase-1 (HO-1) enzyme : learning from the first case with human HO-1deficiency
- Principal Investigator
  
  KOIZUMI Shoichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
Analysis of Alu-mediated genomic deletion in a case with hemeooxygenase-1 deficiencyPrincipal Investigator
- Principal Investigator
  
  SAIKAWA Yutaka
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa university
ヘムオキシゲナーゼ1欠損症の発見:その病態の生化学的,分子生物学的解析
- Principal Investigator
  
  KOIZUMI Shoichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
The first human case with heme oxygenase-1 deficiency : investigation of vascular endothelial injuries and an experimental study for gene therapy
- Principal Investigator
  
  KOIZUMI Shoichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University
Identification and cDNA cloning of the transcriptional factors regulating the tissue-specific expression of human alpha-folate receptor genePrincipal Investigator
- Principal Investigator
  
  SAIKAWA Yutaka
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kanazawa University

All 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Dense methylation of type 1 and type 2 regulatory regions of the CD10 gene promoter in infant acute lymphoblastic leukemia with MLL/AF4 fusion gene.2010
- Author(s)
  Ikawa Y, Sugimoto N, Koizumi S, Yachie A, Saikawa Y.
- Journal Title
  
  J Pediatric Hematology Oncology
  
  Volume: 32 Pages: 4-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] 骨髄系造血のコンピューターシミュレーション2010
- Author(s)
  犀川太
- Journal Title
  
  金沢大学十全医学会雑誌第119巻
  
  Pages: 120-121
- NAID
  10027786977
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591248
[Journal Article] 骨髄系造血のコンピューターシミュレーション2010
- Author(s)
  犀川太
- Journal Title
  
  金沢大学十全医学会雑誌
  
  Volume: 119 Pages: 120-121
- NAID
  10027786977
- Data Source
  KAKENHI-PROJECT-20591248
[Journal Article] Minimal residual disease-based augmented therapy in childhood acute lymphoblastic leukemia2010
- Author(s)
  Yamaji K., Saikawa Y.
- Journal Title
  
  Pediatric Blood and Cancer 55
  
  Pages: 1287-1295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591248
[Journal Article] Dense methylation of type1 and type2 regulatory regions of the CD10 gene promoter in infant acute lymphoblastic leukemia with MLL/AF4 fusion gene.2010
- Author(s)
  Ikawa Y, Sugimoto N, Koizumi S, Yachie A, Saikawa Y.
- Journal Title
  
  J Pediatric Hematology Oncology 32(1)
  
  Pages: 4-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] Dense methylation of types 1 and 2 regulatory regions of the CD10 gene promoter in infant acute lymphoblastic leukemia with MLL/AF4 fusion gene2010
- Author(s)
  Ikawa Y., Saikawa Y.
- Journal Title
  
  J Pediatr Hematol Oncol 32
  
  Pages: 4-10
- NAID
  120001939296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591248
[Journal Article] Lead-pipe colon revisited in chronic graft-versus-host disease.2008
- Author(s)
  Saikawa Y, Ikawa Y, Kagaya T, Koizumi S.
- Journal Title
  
  J Pediatr Gastroenterol Nutr 46
  
  Pages: 463-463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] Right homonymous hemianopsia following allogenic haematopoietic stem cell transplantation.2008
- Author(s)
  Saikawa Y, Horisawa T, Mase S, Araki R, Ikawa Y, Kuroda R, Nishimura R, Koizumi S.
- Journal Title
  
  Eur J Haematol. 80(6)
  
  Pages: 551-551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] Conputational Hematology in systems biology2008
- Author(s)
  Horisawa T., Komatsuzaki T., Saikawa Y.
- Journal Title
  
  Cellular automata LNCS5191
  
  Pages: 486-493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591248
[Journal Article] Lead-pipe colon revisited in chronic graft-versus-host disease.2008
- Author(s)
  Saikawa Y, Ikawa Y, Kagaya T, Koizumi S.
- Journal Title
  
  J Pediatr Gastroenterol Nutr 46(5)
  
  Pages: 483-483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591275
[Journal Article] Monoblastic sarcoma of the kidneys in an infant leukaemia2007
- Author(s)
  Y.Ikawa, Y.Saikawa
- Journal Title
  
  European Journal of Haematology 78
  
  Pages: 181-181
- NAID
  120001133467
- Data Source
  KAKENHI-PROJECT-17591073
[Journal Article] Pancreatic and Renal Involvement in pediatric Acute Lymphoblastic Leukemia/Lymphoma2007
- Author(s)
  Y.Ikawa, Y.Saikawa, et al.
- Journal Title
  
  Journal of Clinical Oncology 25
  
  Pages: 451-453
- Data Source
  KAKENHI-PROJECT-17591073
[Journal Article] Granulopoiesis in Computational Hematology2006
- Author(s)
  Y.Saikawa, et al.
- Journal Title
  
  Book of abstract, International Conference of Computational Methods in Systems Biology, 2006
  
  Pages: 13-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591073
[Journal Article] Granulopoiesis in Computational Hematology2006
- Author(s)
  Y.Saikawa, T.Komatsuzaki, et al.
- Journal Title
  
  Book of abstract,International Conference of Computational Methods in Systems Biology,2006 ?
  
  Pages: 13-14
- Data Source
  KAKENHI-PROJECT-17591073
[Journal Article] Hemophagocytic alveolar rhabdomyosarcoma.2006
- Author(s)
  Saikawa Y, Tone Y, Ikawa Y, Maeba H, Koizumi S, Minato H.
- Journal Title
  
  J Clin Oncol 24
  
  Pages: 2783-6789
- Data Source
  KAKENHI-PROJECT-17390298
[Journal Article] Hemophagocytic alveolar rhabdomyosarcoma.2006
- Author(s)
  Y.Saikawa, T.Tone, et al.
- Journal Title
  
  Journal of Clinical Oncology 24
  
  Pages: 5783-5784
- Data Source
  KAKENHI-PROJECT-17591073
[Journal Article] Hemophagocytic Alveolar Rhabdomyosarcoma2006
- Author(s)
  Y.Saikawa, et al.
- Journal Title
  
  Journal of Clinical Oncology 24・36
  
  Pages: 5783-5784
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591073
[Journal Article] Granulopoiesis in Computational Hematology2006
- Author(s)
  Yutaka Saikawa
- Journal Title
  
  Book of Abstracts, International Conference of Computational Methods in Systems Biology
  
  Pages: 13-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591073
[Journal Article] Hemophagocytic Alveolar Rhabdomyosarcoma2006
- Author(s)
  Yutaka Saikawa
- Journal Title
  
  Journal of Clinical.Oncology 24・36
  
  Pages: 5783-5784
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591073
[Journal Article] Glomerular proteinuria induces heme oxygenase-I gene expression within renal epithelial cells2005
- Author(s)
  Shimizu, M., Ohta, K., Yang, Y., Nakai, A., Toma, T., Saikawa, Y., Kasahara, Y., Yachie, A., Yokoyama, H., Seki, H., Koizumi, S
- Journal Title
  
  Pediatric Research 58
  
  Pages: 666-671
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390298
[Journal Article] Glomerular proteinuria induces heme oxygenase-1 gene expression within renal epithelial cells.2005
- Author(s)
  Shimizu M, Ohta K, Yang Y, Nakai A, Toma T, Saikawa Y, Kasahara Y, Yachie A, Yokoyama H, Seki H, Koizumi S.
- Journal Title
  
  Pediatric Research 58
  
  Pages: 666-671
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390298
[Journal Article] Glomerular proteinuria induces heme oxygenase-1 gene expression within renal epithelial cells.2005
- Author(s)
  Shimizu M, Ohta K, Yang Y, Nakai A, Toma T, Saikawa Y, Kasahara H, Yachie A, Yokoyama H, Seki H, Koizumi S.
- Journal Title
  
  Pediatric Research 58
  
  Pages: 666-671
- Data Source
  KAKENHI-PROJECT-17390298
[Presentation] Dense methylation patterns of CD10-negative infant acute lymphoblastic leukemia with MLL gene arrangements2009
- Author(s)
  Saikawa Y
- Organizer
  100^<th> annual meeting of American Association of Cancer Research
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-20591248
[Presentation] Promoter DNA methylation of CD10 in infant acute lymphoblastic leukemia with MLL/AF4 fusion gene.2009
- Author(s)
  Y.Ikawa, N.Sugimoto, S.Koizumi, A.Yachie, Y.Saikawa
- Organizer
  2009 annual meeting of the American Society of Clinical Oncology
- Place of Presentation
  Orlando Convention Center, USA
- Year and Date
  2009-05-29
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] Dense Methylation Patterns of CD10 Promoters in CD 10-Negative Infant Acute Lymphoblastic Leukemia (ALL) with Mixed-Lineage Leukemia (MLL) Gene Rearrangements2009
- Author(s)
  Yasuhiro Ikawa, Naotoshi Sugimoto, Shintaro Mase, Rie Kuroda, Raita Araki^1 Ryosei Nishimura, Toru Horisawa, Naoki Okada, Shoichi Koizumi, Akihiro Yachie, Yutaka Saikawa
- Organizer
  100th annual meeting of the American Association of Cancer Research
- Place of Presentation
  Denver Convention Center, USA
- Year and Date
  2009-04-18
- Data Source
  KAKENHI-PROJECT-20591275
[Presentation] Computational Hematology in Systems Biology2008
- Author(s)
  Saikawa Y
- Organizer
  8th International Conference on Cellular Automata for Research and Industry
- Place of Presentation
  Yohohama, Japan
- Data Source
  KAKENHI-PROJECT-20591248
[Presentation] Heme oxygenase(HO)-1 and hematopoiesis: a lesso from the first human case of HO-1 deficlency2007
- Author(s)
  Koizumi S, Yachie A, Kasahara Y, Saikawa Y, Yoma T, Ohta Ka, Ohta Ku
- Organizer
  36th Annual Scientific Meeting of the ISEH-Societyfor Hematology and Stem Cells
- Place of Presentation
  Hamburg, Germany
- Data Source
  KAKENHI-PROJECT-17390298
[Presentation] Heme oxygenase (HO)-1 and hematopoiesis : a lesson from the first human case of HO-1 deficiency2007
- Author(s)
  Koizumi, S., Yachie, A., Kasahara, Y., Saikawa, Y., Niida, Y., Yoma, T., Ohta, Ka., Ohta, Ku
- Organizer
  36th Annual Scientific Meeting of the ISEH-Society for Hematology and Stem Cells
- Place of Presentation
  Hamburg, Germany
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390298
[Presentation] Heme oxygenase(HO)-1 and hematopoiesis: a lesson from the first human case of HO-1 deficiency.2007
- Author(s)
  Koizumi S, Yachie A, Kasahara Y, Saikawa Y, Niida Y, Yoma T, Ohta Ka, Ohta ku
- Organizer
  36th Annual Scientific Meeting of the ISEH-Society for Hematology and Stem Cells
- Place of Presentation
  Hamburg, Germany
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390298
[Presentation] 再発を予見する～コンピュータシミュレーションによる白血病幹細胞の動態解析～
- Author(s)
  犀川　太、小松崎　俊彦
- Organizer
  第15回金沢医科大学研究推進セミナー　｢難病攻略めざすシステム生物学｣
- Place of Presentation
  金沢医科大学（石川県内灘町）
- Data Source
  KAKENHI-PROJECT-24591562

1. KOIZUMI Shoichi (50019973)

# of Collaborated Projects: 6 results

# of Collaborated Products: 14 results
2. KOMATSUZAKI Toshihiko (80293372)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. YACHIE Akihiro (40210281)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. OHTA Kunio (00303280)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. NIIDA Yo (40293344)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. OHTA Kazuhide (20283129)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. KASAHARA Yoshihito (30204366)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
8. WADA Tatzou (30313646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NISHIMURA Ryousei (50324116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. SUGIMOTO Naotoshi (80272954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. 西山宣昭 (10198525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 八田稔久 (20238025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Saikawa Yutaka 犀川 太

SAIKAWA Yutaka 犀川 太

Research Projects

Research Products

Co-Researchers

Computing analysis of leukemic stem cell dynamics in acute myelocytic leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Computational leukemic stem cell models in systems biology for analyses of cell kinetics in leukemic relapse and development of risk-stratified chemotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Computational leukemic stem cell models in systems biology for predicting relapse and development of risk-stratified chemotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Physiological importance of heme oxygenase-1 on hemopoiesis, inflammation and immunology system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Heme oxygenase-1 deficiency and failure of human defense mechanisms against generalized chronic inflammation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Kinetic analysis of minimal residual disease using 3-dimentinal computational models of human granulopoiesis and development of risk of relapse-stratified treatment of pediatric leukemia.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マクロファージの活性化とヘムオキシゲナーゼ1発現:癌細胞における血管新生との相関

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Multilateral-physiological and functional evidences of the heme oxygenase-1 (HO-1) enzyme : learning from the first case with human HO-1deficiency

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Alu-mediated genomic deletion in a case with hemeooxygenase-1 deficiencyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヘムオキシゲナーゼ1欠損症の発見:その病態の生化学的,分子生物学的解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The first human case with heme oxygenase-1 deficiency : investigation of vascular endothelial injuries and an experimental study for gene therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and cDNA cloning of the transcriptional factors regulating the tissue-specific expression of human alpha-folate receptor genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Dense methylation of type 1 and type 2 regulatory regions of the CD10 gene promoter in infant acute lymphoblastic leukemia with MLL/AF4 fusion gene.2010

Author(s)

Journal Title

Saikawa Yutaka 犀川太

SAIKAWA Yutaka 犀川太