HATO Naohito 羽藤直人

Researcher Number	60284410
Other IDs
External Links
Affiliation (Current)	2025: 愛媛大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2025: 愛媛大学, 医学系研究科, 教授 2016 – 2023: 愛媛大学, 医学系研究科, 教授 2014 – 2015: 愛媛大学, 医学(系)研究科(研究院), 教授 2012 – 2013: 愛媛大学, 医学(系)研究科(研究院), 准教授 2012: 愛媛大学, 医学部附属病院 … More 2008 – 2012: Ehime University, 大学院・医学系研究科, 准教授 2010: 愛媛大学, 医学部附属病院, 准教授 2008: Ehime University, 医学部・附属病院, 准教授 2002 – 2007: 愛媛大学, 医学部附属病院, 講師 1999: 愛媛大, 医学部附属病院, 助手 1998: 愛媛大学, 医学部・付属病院, 助手 1998: Ehime University, School of Medicine, Research Associate, 医学部附属病院, 助手 1997 – 1998: 愛媛大学, 医学部・附属病院, 助手 1996: 愛媛大学, 医学部・付属病院, 助手 Less
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology Except Principal Investigator Otorhinolaryngology / Otorhinolaryngology / Basic Section 49020:Human pathology-related / Plastic surgery
Keywords	Principal Investigator 顔面神経麻痺 / 単純ヘルペスウイルス / 顔面神経 / ベル麻痺 / 神経再生 / DDS / 栄養因子 / 再生医療 / iNOS / NO … More / HSV-1 / 再活性化 / 経鼓膜鼓室内投与 / ゼラチンハイドロゲル / 神経科学 / 冷却刺激 / edarabone / facial nerve paralysis / Bell' s palsy / 脱髄 / エダラボン / 蛍光染色 / galectin-7 / 免疫染色 / 内耳毒性 / Galectin-7 / 真珠腫 / 神経切断 / RNA解析 / マイクロアレイ法 / 神経挫滅 / 圧迫 / 徐放化神経栄養因子 / 後遺症 / bFGF / 徐放化ゼラチ / 神経過誤支配 / 病的共同運動 / 膝神経節 / マウス / 抗T細胞抗体 … More Except Principal Investigator GDNF / 内耳虚血 / 突発性難聴 / アポトーシス / 一過性内耳虚血 / PCR / 顔面神経麻痺 / 個別化治療 / 唾液腺癌 / 粘表皮癌 / 腺様嚢胞癌 / 唾液腺腫瘍 / AM-111 / sudden onset hearing loss / glutamate antagonist / ginsenoside Rb1 / apoptosis / 神経幹細胞 / 急性難聴 / excitotoxicity / グルタミン酸拮抗剤 / 内有毛細胞 / 活性酸素 / スナネズミ / 内耳低温療法 / 伝音難聴 / 先天性外耳道閉鎖症 / 外耳道閉鎖症 / 鼓膜浅在化 / 軟骨移植 / 脱髄 / Zoster sine herpete / ベル麻痺 / 分子標的薬 / キメラ遺伝子 / 分子病態 / 臨床病理学 / 分子病理学的研究 / 多施設共同研究 / sudden sensorineural deafness / predonisone / free daical scavenger / post-ischemic process / transient cochlear ischemia / ジンセノサイド / エダラボン / インシュリン様細胞増殖因子 / ゼラチンハイドロゲル / プロサポシン由来合成ペプチド / 治療の窓 / 一過性虚血 / プレドニゾロン / フリーラジカル消去剤 / 虚血後のプロセス / stem cell / prosaposin / glutamate transporter / connexin 26 / Bax / cochlear ischemia / 細胞治療 / 有毛細胞脱落 / ラセン神経節 / 血管条 / therapeutic time window / 細胞移植 / 活性化酸素 / NO / 血管条病変 / 骨髄幹細胞 / プロサポシン / ジンセノサイドRb1 / グルタミン酸トランスポータ / コネキシン26 / アポトーシス関連タンパク / 虚血性内耳障害 / ischemic hearing loss / free radical scavenger / 低体温療法 / ラセン神経節細胞 / 内耳障害防御 / 虚血性難聴 / ジンチノサイトRb1 / フリーラジカル捕捉剤 / eary diagnosis / Zostes sine herpete / Blood nerve barrier / Animal model / Herpes simplex virus / Bell's palsy / PCR法 / HSV-1 / Ramsay Hunt症候群 / 早期診断 / zoster sine herpete / blood nerve barrier / 顔面神経麻痺モデル動物 / ヒト単純ヘルペスウイルス1型 / 騒音下語音聴取 / プラグ接続 / チタン製骨導端子 / 全埋込み型人工中耳 / 骨導聴覚 / 超磁歪素子 / Bonebridge / 超磁磁歪素子 / BAHA / 人工中耳 / 埋め込み型補聴器 / 骨導 / 難聴の治療 / 低酸素親和性 / 高酸素親和性 / ナノカプセル / 外有毛細胞 / ABR / 1-LEH / 有毛細胞 / l-LEH / h-LEH / 人工赤血球 / リアルタイムPCR / 神経端側縫合 / Myogenin / リアルタイム PCR / 端側神経縫合 / 神経信号付加 / 顔面神経不全麻痺 / 有毛細胞障害 / 突発難聴 / microarray法 / GPCR / 致死的虚血 / 先行虚血 / 虚血関連蛋白質 / 遺伝子発現 / 虚血関連蛋白 / 再発の防御 / 虚血耐性 / 虚血再発の防御 / ischemic tolerance / 虚血関連タンパク / 虚血関連遺伝子 / 鼓膜浅在化の防御 / 外耳道再閉鎖 / 皮膚弁懐死 / 鼓室形成術 / 肉芽性再閉鎖 / 耳介形成術 / シリコンチューブ / 鼓膜形成 / 軟骨 / 外耳道造成術 / 肋軟骨 / 軟骨カッター / 伝音性難聴 / 肉芽組織 / 外耳道造設術 / 免疫応答 / マウス / 単純ヘルペスウイルス Less

加齢性難聴における水素ガスの予防効果とその分子機構の解明Principal Investigator
- Principal Investigator
  
  羽藤直人
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Ehime University
Molecular pathological analysis of salivary gland carcinomas promoting personalized medicine: A large-scale multicenter study
- Principal Investigator
  
  Inagaki Hiroshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Nagoya City University
Development of a novel treatment for severe facial nerve palsy by intratympanic administration of sustained-release neurotrophic factorPrincipal Investigator
- Principal Investigator
  
  Hato Naohito
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Ehime University
Molecular pathological analysis of salivary gland carcinomas focusing on personalized medicine: A large-scale multicenter study
- Principal Investigator
  
  Inagaki Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Nagoya City University
Development of a new treatment for sequelae of facial nerve palsyPrincipal Investigator
- Principal Investigator
  
  Hato Naohito
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
Expression of Galectin-7 in cholesteatoma matrix and its clinical significancePrincipal Investigator
- Principal Investigator
  
  HATO NAOHITO
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
超磁歪素子を用いた次世代埋め込み型骨導補聴器の開発とその臨床評価
- Principal Investigator
  
  暁清文
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
Dynamic change of Myogenin in denervated rat mimetic muscle: Does the neural repair repress its expression ?
- Principal Investigator
  
  YAMAMOTO Yuhei
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Plastic surgery
- Research Institution
  Hokkaido University
RNA expression in facial muscle following damage to the facial nerve -As a tool of early prognostic diagnosis-Principal Investigator
- Principal Investigator
  
  HATO Naohito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
Liposome-encapsulated hemoglobin alleviates inner eardamage after transient cochlear ischemia in the gerbil
- Principal Investigator
  
  GYO Kiyofumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
Proteomic analysis of ischemic cochlear damage as a diagnostic tool of sudden sensorineural hearing loss
- Principal Investigator
  
  GYO Kiyofumi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
Treatment of facial nerve synkinesis by basic fibroblast growth factor impregnated in a biodegradable hydrogelPrincipal Investigator
- Principal Investigator
  
  HATO Naohito
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
Treatment modality of ischemic hearing loss based on therapeutic time window
- Principal Investigator
  
  GYO Kiyofiuni
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
再生軟骨を利用した外耳道造成術の開発とその臨床応用上の問題点の研究
- Principal Investigator
  
  暁清文
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
Role of nitric oxide in facial nerve paralysis in mice induced by herpes simplex type 1 infectionPrincipal Investigator
- Principal Investigator
  
  HATO Naohito
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
New strategy for the treatment of sudden-onset hearing loss based on ischemic cell damage theory
- Principal Investigator
  
  GYO Kiyofumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
軟骨を利用した新しい外耳道作成術の研究
- Principal Investigator
  
  暁清文
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
ベル麻痺の神経障害機構とウイルスゲノム解析Principal Investigator
- Principal Investigator
  
  羽藤直人
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
Development of treatment modalities for ischemic cochlear damage
- Principal Investigator
  
  GYO Kiyofumi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
単純ヘルペスウイルス再活性化による顔面神経麻痺モデルに関する基礎研究Principal Investigator
- Principal Investigator
  
  羽藤直人
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
Etiopathology and eary diagnosis of Bell's palsy
- Principal Investigator
  
  MURAKAMI Shingo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University
ベル麻痺の原因と病態に関する基礎的研究
- Principal Investigator
  
  柳原尚明
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Ehime University

[Journal Article] The Landscape of MYB/MYBL1- and Peri-MYB/MYBL1-Associated Rearrangements in Adenoid Cystic Carcinoma2023
- Author(s)
  Ueda Kaori, Murase Takayuki, Inagaki Hiroshi
- Journal Title
  
  Modern Pathology
  
  Volume: 36 Issue: 10 Pages: 100274-100274
- DOI
  10.1016/j.modpat.2023.100274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15388, KAKENHI-PROJECT-22K06939, KAKENHI-PROJECT-23K06432, KAKENHI-PROJECT-23K06469, KAKENHI-PROJECT-21H02704
[Journal Article] Prognostic scores for patients with salivary adenoid cystic carcinoma without lymph node metastasis2023
- Author(s)
  Shimoda H, Teshima M, Murase T, Nagao T, Kusafuka K, Nakaguro M, Urano M, Taguchi KI, Yamamoto H, Kano S, Tada Y, Tsukahara K, Okami K, Onitsuka T, Fujimoto Y, Kawakita D, Sakurai K, Hanai N, Nagao T, Kawata R, Hato N, Nibu KI, Inagaki H.
- Journal Title
  
  Oral Oncology
  
  Volume: 145 Pages: 106491-106491
- DOI
  10.1016/j.oraloncology.2023.106491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06939, KAKENHI-PROJECT-23K06432, KAKENHI-PROJECT-23K06469, KAKENHI-PROJECT-21H02704
[Journal Article] Intratympanic Insulin-like Growth Factor-1 Administration Via the Otic Bulla in a Severe Facial Paralysis Model2021
- Author(s)
  Kimura Takuya、Yamada Hiroyuki、Teraoka Masato、Joko Tomonori、Iwata Shinji、Tabata Yasuhiro、Wakisaka Hiroyuki、Hato Naohito
- Journal Title
  
  Otology & Neurotology
  
  Volume: 42 Issue: 9 Pages: e1376-e1381
- DOI
  10.1097/mao.0000000000003263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09715
[Journal Article] Pathological evaluation of tumor grade for salivary adenoid cystic carcinoma: A proposal of an objective grading system2021
- Author(s)
  Morita N, Murase T, Ueda K, Nagao T, Kusafuka K, Nakaguro M, Urano M, Taguchi KI, Yamamoto H, Kano S, Tada Y, Tsukahara K, Okami K, Onitsuka T, Fujimoto Y, Kawakita D, Sakurai K, Nagao T, Hanai N, Kawata R, Hato N, Otsuki N, Nibu KI, Inagaki H.
- Journal Title
  
  Cancer Science
  
  Volume: 112(3) Issue: 3 Pages: 1184-1195
- DOI
  10.1111/cas.14790
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10508, KAKENHI-PROJECT-18H02633, KAKENHI-PROJECT-19H03804, KAKENHI-PROJECT-21H02704, KAKENHI-PROJECT-20K07417, KAKENHI-PROJECT-21K15388
[Journal Article] The impact of clinicopathological factors on clinical outcomes in patients with salivary gland adenoid cystic carcinoma: a multi-institutional analysis in Japan2020
- Author(s)
  Kawakita D, Murase T, Ueda K, Kano S, Tada Y, Tsukahara K, Okami K, Onitsuka T, Fujimoto Y, Matoba T, Sakurai K, Nagao T, Hanai N, Kawata R, Hato N, Nibu KI, Urano M, Taguchi KI, Nakaguro M, Kusafuka K, Yamamoto H, Nagao T, Inagaki H.
- Journal Title
  
  International Journal of Cinical Oncology
  
  Volume: 25(10) Issue: 10 Pages: 1774-1785
- DOI
  10.1007/s10147-020-01731-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10508, KAKENHI-PROJECT-19K18779, KAKENHI-PROJECT-19KK0202, KAKENHI-PROJECT-18H02633, KAKENHI-PROJECT-20K07417
[Journal Article] Central pathology review of salivary gland adenoid cystic carcinoma2020
- Author(s)
  Ueda K、Murase T、Nagao T、Kusafuka K、Urano M、Yamamoto H、Nakaguro M、Taguchi K、Masaki A、Hirai H、Kawakita D、Tsukahara K、Hato N、Nagao T、Fujimoto Y、Sakurai K、Hanai N、Kano S、Onitsuka T、Okami K、Nibu K、Tada Y、Kawata R、Inagaki H
- Journal Title
  
  Head & Neck
  
  Volume: X Issue: 8 Pages: 1721-1727
- DOI
  10.1002/hed.26081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09386, KAKENHI-PROJECT-18K16095, KAKENHI-PROJECT-19K16568, KAKENHI-PROJECT-17K08705, KAKENHI-PROJECT-20K10508, KAKENHI-PROJECT-18H02633, KAKENHI-PROJECT-20K07417
[Journal Article] 顔面神経麻痺の診断と治療2017
- Author(s)
  羽藤直人
- Journal Title
  
  Nippon Jibiinkoka Gakkai Kaiho
  
  Volume: 120 Issue: 1 Pages: 58-61
- DOI
  10.3950/jibiinkoka.120.58
- NAID
  130005330302
- ISSN
  0030-6622, 1883-0854
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-16K11185
[Journal Article] 【顔面神経麻痺のリハビリテーションによる機能回復】難治性の顔面神経麻痺の治療　私の工夫(2)2017
- Author(s)
  羽藤直人
- Journal Title
  
  ENTONI
  
  Volume: 203号 Pages: 71-75
- Data Source
  KAKENHI-PROJECT-16K11185
[Journal Article] Facial paralysis induced by ear inoculation of herpes simplex virus in rat2017
- Author(s)
  Fujiwara T, Matsuda S, Tanaka J, Hato N
- Journal Title
  
  Auris Nasus Larynx.
  
  Volume: 44(1): Issue: 1 Pages: 58-64
- DOI
  10.1016/j.anl.2016.04.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11185
[Journal Article] Myogenin expression in facial muscle following damage to the facial nerve2012
- Author(s)
  Teraoka; Hato; Takahashi; Komobuchi; Sawai; Okada; Hakuba
- Journal Title
  
  Acta Oto-Laryngologica
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591884
[Journal Article] Myogenin expression in facial muscle following damage to the facial nerve2012
- Author(s)
  Teraoka M, Hato N, Takahashi H, Komobuchi H, Sawai N, Okada M, Hakuba N
- Journal Title
  
  Acta Otolaryngol
  
  Volume: 132(7) Pages: 783-787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591884
[Journal Article] Liposome-encapsulated hemoglobin alleviates hearing loss after transient cochlear ischemia and reperfusion in the gerbil2012
- Author(s)
  Okada M, Kawaguchi AT, Hakuba N, Takeda S, Hyodo J, Imai K, Hato N, Gyo K.
- Journal Title
  
  Artif Organs
  
  Volume: 36(2) Pages: 178-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659308
[Journal Article] Bell 麻痺、Hunt 症候群2010
- Author(s)
  羽藤直人
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 28 Pages: 338-339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591884
[Journal Article] Bell麻痺、Hunt症候群2010
- Author(s)
  羽藤直人
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 28 Pages: 338-339
- Data Source
  KAKENHI-PROJECT-22591884
[Journal Article] Local hypothermia in the treatment of idiopathic sudden sensorineural hearing loss2010
- Author(s)
  Hato N, Hyodo J, Takeda S, Takagi D, Okada M, Hakuba N, Gyo K
- Journal Title
  
  ANL
  
  Volume: 37(5) Pages: 626-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390442
[Journal Article] Local hypothermia in the treatment of idiopathic sudden sensorineural hearing loss.2010
- Author(s)
  Hato N, Hyodo J, Takeda S, Takagi D, Okada M, Hakuba N, Gyo K
- Journal Title
  
  ANL 37(5)
  
  Pages: 626-630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390442
[Journal Article] Ischemic tolerance in the cochlea2009
- Author(s)
  Takeda S, Hata R, Cao F, Yoshida T, Hakuba N, Hato N, Gyo K.
- Journal Title
  
  Neuroscience Letter
  
  Volume: 25, 462(3) Pages: 263-266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390442
[Journal Article] Ischemic tolerance in the cochlea2009
- Author(s)
  Takeda S, Hata R, Cao F, Yoshida T, Hakuba N, Hato N, Gyo K
- Journal Title
  
  Neurosci Lett 25,462(3)
  
  Pages: 263-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390442
[Journal Article] Glutamate agonist causes irreversible degeneration of inner hair cells.2009
- Author(s)
  Hyodo J, Hakuba N, Hato N, Takeda S, Okada M, Omotehara Y, Gyo K.
- Journal Title
  
  Neurorepor t
  
  Volume: 23 ; 20(14) Pages: 1255-1259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390442
[Journal Article] Glutamate agonist causes irreversible degeneration of inner hair cells.2009
- Author(s)
  Hyodo J, Hakuba N, Hato N, Takeda S, Okada M, Omotehara Y, Gyo K
- Journal Title
  
  Neuroreport. 23;20(14)
  
  Pages: 1255-1259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390442
[Journal Article] Insulin-like growth factor 1 treatment via hydrogels rescues cochlear hair cells from ischemic injury2008
- Author(s)
  Fujiwara T, Hato N, Nakagawa T,Tabata Y et.al.
- Journal Title
  
  Neuroreport 29 19(16)
  
  Pages: 1585-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] Valacyclovir for the treatment of Bell's palsy2008
- Author(s)
  Hato N, Sawai N, Teraoka M, Wakisaka H, et.al.
- Journal Title
  
  Expert Opin Pharmacother 9(14)
  
  Pages: 2531-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] Postischemic mild hypothermia alleviates hearing loss because of transient ischemia2008
- Author(s)
  Takeda S, Hakuba N, Yoshida T, Fujita K, Hato N, Hata R, Hyodo J, Gyo K.
- Journal Title
  
  Neuroreport 27 ; 19(13)
  
  Pages: 1325-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] Postischemic mild hypothermia alleviates hearing loss because of transient ischemia.2008
- Author(s)
  Takeda S, Hakuba N, Yoshida T, Fujita K, Hato N, Hata R, Hyodo J, Gyo K
- Journal Title
  
  Neuroreport 27;19(13)
  
  Pages: 1325-1328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390442
[Journal Article] Myasthenia gravis experimentally induced with muscle-specific kinase2008
- Author(s)
  Shigemoto K, Kubo S, Jie C, Hato N, et,al.
- Journal Title
  
  Ann N Y Acad Sci 1132
  
  Pages: 93-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] Insulin-like growth factor 1 treatment via hydrogels rescues cochlear hair cells from ischemic injury.2008
- Author(s)
  Fujiwara T, Hato N, Nakagawa T, Tabata Y, Yoshida T, Komobuchi H, Takeda S, Hyodo J, Gyo K
- Journal Title
  
  Neuroreport. 29;19(16)
  
  Pages: 1585-1588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390442
[Journal Article] 再生促進を目的とした顔面神経減荷手術生体吸収性ゼラチンハイドロゲルを用いたbFGF の徐放投与2008
- Author(s)
  羽藤直人, 菰渕勇人, 寺岡正人, 暁清文
- Journal Title
  
  Facial N Research 27
  
  Pages: 218-220
- NAID
  10021291516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] Steroid and antiviral treatment for Bell's palsy2008
- Author(s)
  Hato N, Murakami S, Gyo K
- Journal Title
  
  Lancet 371
  
  Pages: 1818-1820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] Steroid and antiviral treatment for Bell's palsy2008
- Author(s)
  Hato N, Murakami S, Gyo K.
- Journal Title
  
  Lancet 371
  
  Pages: 1818-1820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] 再生促進を目的とした顔面神経減荷手術生体吸収性ゼラチンハイドロゲルを用いたbFGFの徐放投与2008
- Author(s)
  羽藤直人, 菰渕勇人, 寺岡正人, 暁清文
- Journal Title
  
  Facial N Research 27
  
  Pages: 218-220
- NAID
  10021291516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] 顔面神経麻痺における組織学的変化は?(Q&A/特集)2008
- Author(s)
  羽藤直人
- Journal Title
  
  JOHNS 24
  
  Pages: 1783-1786
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] 顔面神経麻痺における組織学的変化は? (Q&A/特集)2008
- Author(s)
  羽藤直人
- Journal Title
  
  JOHNS 24
  
  Pages: 1783-1786
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] 突発性難聴に対する内耳低温療法2007
- Author(s)
  羽藤直人, 他
- Journal Title
  
  愛媛医学 26
  
  Pages: 292-296
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390459
[Journal Article] 顔面神経研究の将来展望再生医療と手術治療の融合顔面神経減荷手術を中心に2007
- Author(s)
  羽藤直人
- Journal Title
  
  Facial Nerve Research 26
  
  Pages: 25-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] Hypothermic therapy for sudden deafness2007
- Author(s)
  Hato, N, et. al.
- Journal Title
  
  Ehime Igaku 26
  
  Pages: 292-296
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390459
[Journal Article] Drug delivery systemを用いたbFGFの顔面神経再生促進効果2007
- Author(s)
  菰渕勇人, 羽藤直人、寺岡正人, 脇坂浩之, 高橋宏尚, 暁清文
- Journal Title
  
  Facial Nerve Research 26
  
  Pages: 41-43
- NAID
  10024480641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] Storage of the incus in the mastoid bowl for use as a columella in staged tympanoplasty2007
- Author(s)
  Gyo K, Hato N, Shinomori Y, Hakuba N.
- Journal Title
  
  Auris Nasus Larynx 34(1)
  
  Pages: 5-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] Valacyclovir and prednisolone treatment for Bell's palsy : a multicenter, randomized, placebo-controlled study2007
- Author(s)
  Hato N, Yamada H, Kohno H, Matsumoto S, Honda N, Gyo K, et.al.
- Journal Title
  
  Otol Neurotol. 28
  
  Pages: 408-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] Repair of a malleus-handle fracture using calcium phosphate bone cement2007
- Author(s)
  Hato N, Okada M, Hakuba N, Hyodo M, Gyo K.
- Journal Title
  
  Laryngoscope 117
  
  Pages: 361-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591976
[Journal Article] 顔面神経減荷手術のコンセプトと展望2005
- Author(s)
  羽藤直人
- Journal Title
  
  Facial N Res Jpn 25
  
  Pages: 25-26
- NAID
  10024480611
- Data Source
  KAKENHI-PROJECT-17591791
[Journal Article] Bell麻痺に対する塩酸バラシクロビルとプレドニゾロン併用療法の効果2005
- Author(s)
  羽藤直人他
- Journal Title
  
  Facial N Res Jpn 25
  
  Pages: 85-87
- NAID
  10024480744
- Data Source
  KAKENHI-PROJECT-17591791
[Journal Article] マウスHSV-1初感染顔面神経麻痺モデルにおけるNOの関与2005
- Author(s)
  河野尚, 羽藤直人他
- Journal Title
  
  Facial N Res Jpn 25
  
  Pages: 33-35
- NAID
  10024480631
- Data Source
  KAKENHI-PROJECT-17591791
[Presentation] Intratympanic administration of growth factor with a gelatin hydrogel on severe facial paralysis2022
- Author(s)
  Naohito Hato
- Organizer
  14th International Facial Nerve Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09715
[Presentation] Middle Ear and Facial Nerve2021
- Author(s)
  Naohito Hato
- Organizer
  7th East Asian Symposium on Otology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09715
[Presentation] 顔面神経麻痺診療の変遷と発展2020
- Author(s)
  羽藤直人
- Organizer
  第30回日本耳科学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09715
[Presentation] 冷却障害による顔面神経麻痺モデルの検討2017
- Author(s)
  上甲智規, 山田啓之, 羽藤直人
- Organizer
  Otology Japan
- Data Source
  KAKENHI-PROJECT-16K11185
[Presentation] 外耳道後壁、保存か削除か－症例の選択法－2014
- Author(s)
  羽藤直人
- Organizer
  日本耳科学会
- Place of Presentation
  新潟市
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26670743
[Presentation] 内耳虚血・循環障害に対する人工酸素運搬体の有用性2013
- Author(s)
  岡田昌浩、白馬伸洋、羽藤直人、暁　清文、川口　章
- Organizer
  第29回　頭頚部自律神経研究会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22659308
[Presentation] Bell 麻痺に対する再生促進顔面神経減荷手術2012
- Author(s)
  羽藤直人、能田淳平、菰渕勇人、澤井尚樹、寺岡正人、暁清文
- Organizer
  第35回日本顔面神経研究会
- Place of Presentation
  福島
- Data Source
  KAKENHI-PROJECT-22591884
[Presentation] Bell麻痺に対する再生促進顔面神経減荷手術2012
- Author(s)
  羽藤直人、能田淳平、菰渕勇人、澤井尚樹、寺岡正人、暁　清文
- Organizer
  第35回　日本顔面神経研究会
- Place of Presentation
  福島
- Data Source
  KAKENHI-PROJECT-22591884
[Presentation] Delayed Decompression Surgery for Severe Facial Nerve Paralysis using bFGF in a Gelatin Hydrogel2012
- Author(s)
  Hato N MD, Nota J MD, Komobuchi H MD, Teraoka M MD, Yamada H MD, Gyo K MD, Yanagihara N MD and Tabata Y* PhD
- Organizer
  The 9th International Conference on Cholesteatoma and Ear Surgery
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-22591884
[Presentation] Facial Nerve Decompression Surgery with Gelatin Containing bFGF2011
- Author(s)
  Hato N
- Organizer
  AAO-HNS
- Place of Presentation
  米国、サンフランシスコ
- Year and Date
  2011-09-14
- Data Source
  KAKENHI-PROJECT-22591884
[Presentation] 内耳虚血・循環障害に対する人工酸素運搬体の有用性2011
- Author(s)
  岡田昌浩、白馬伸洋、羽藤直人、暁清文、川口章
- Organizer
  第29回頭頚部自律神経研究会
- Place of Presentation
  大阪市
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PROJECT-22659308
[Presentation] 内耳虚血・循環障害に対する人工酸素運搬体の有用性の検討2011
- Author(s)
  岡田昌浩、竹田将一郎、白馬伸洋、羽藤直人、暁清文、兵藤純、川口章
- Organizer
  愛媛大学大学院医学専攻研究発表会
- Place of Presentation
  東温市
- Year and Date
  2011-03-04
- Data Source
  KAKENHI-PROJECT-22659308
[Presentation] 内耳虚血・再灌流障害に対する人工酸素運搬体の有用性の検討2010
- Author(s)
  岡田昌浩、川口章、竹田将一郎、白馬伸洋、羽藤直人、暁清文
- Organizer
  第111回日本耳鼻咽喉科学会総会・学術講演会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-22659308
[Presentation] Lipostome-encapsulated hemoglobin alleveates hearing loss after transient cochlear ischemia and reperfusion2010
- Author(s)
  M Okada, A Kawaguchi, N Hakuba, N Omotehara, S Takeda, J Hyodo, N Hato, K Gyo
- Organizer
  47th Innner Ear Biology Workshop
- Place of Presentation
  チェコ
- Data Source
  KAKENHI-PROJECT-22659308
[Presentation] 内耳虚血・再灌流障害に対する人工酸素運搬体の有用性の検討2010
- Author(s)
  岡田昌浩、川口章、竹田将一郎、白馬伸洋、羽藤直人、暁清文
- Organizer
  第111回日本耳鼻咽喉科学会総会・学術講演会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-20390442
[Presentation] Lipostome-encapsulated hemoglobin alleveates hearing loss after transient cochlearischemia and reperfusion2010
- Author(s)
  M.Okada, A.T.Kawaguchi, N.Hakuba, N.Omotehara, S.Takeda, J.Hyodo, N.Hato, K.Gyo
- Organizer
  47th Innner Ear Biology Workshop
- Place of Presentation
  チェコ
- Data Source
  KAKENHI-PROJECT-20390442
[Presentation] 側頭骨骨折への対応:顔面神経障害を中心に2010
- Author(s)
  羽藤直人
- Organizer
  顔面神経研究会
- Place of Presentation
  福岡
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-22591884
[Presentation] 内耳における虚血耐性2009
- Author(s)
  竹田将一郎、吉田正、白馬伸洋、羽藤直人、暁清文
- Organizer
  第19回日本耳科学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390442
[Presentation] ウイルス性麻痺の後療法2008
- Author(s)
  羽藤直人
- Organizer
  マイクロサージェリー学会
- Place of Presentation
  新潟
- Year and Date
  2008-11-05
- Data Source
  KAKENHI-PROJECT-19591976
[Presentation] 一過性虚血後の内耳に対する低体温の保護効果2008
- Author(s)
  竹田将一郎、白馬伸洋、兵頭純、羽藤直人、暁清文
- Organizer
  第18回日本耳科学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20390442
[Presentation] 顔面神経麻痺の後遺症評価「柳原法における後遺症評価」2008
- Author(s)
  羽藤直人. 澤井尚樹、寺岡正人、暁清文
- Organizer
  第31回日本顔面神経研究会
- Place of Presentation
  東京
- Year and Date
  2008-05-29
- Data Source
  KAKENHI-PROJECT-19591976
[Presentation] 内耳低温療法を用いた突発性難聴の治療検討2008
- Author(s)
  高木大樹、羽藤直人、兵頭純、暁清文
- Organizer
  第53回日本聴覚医学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390442
[Presentation] 人工神経を用いた顔面神経再生2007
- Author(s)
  羽藤直人
- Organizer
  第22回日本整形外科学会基礎学術集会
- Place of Presentation
  浜松
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-19591976
[Presentation] 突発性難聴に対する内耳低温療法2007
- Author(s)
  羽藤直人, 他
- Organizer
  第69回耳鼻咽喉科臨床学会総会・学術講演会
- Place of Presentation
  東京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390459
[Presentation] 人工組織による再建人工神経を用いた顔面神経再生2007
- Author(s)
  羽藤直人
- Organizer
  日本整形外科学会基礎学術集会
- Place of Presentation
  浜松
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-19591976
[Presentation] 突発性難聴に対する内耳低温療法2007
- Author(s)
  羽藤直人, 他
- Organizer
  第69目耳鼻咽喉科臨床学会総会・学術講演会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-18390459
[Presentation] Hypothermic therapy for sudden deafness2007
- Author(s)
  Hato, N, et. al.
- Organizer
  69th Annual Meeting of Practica Oto-Rhino-Laryngologica
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390459
[]
[]
[]

1. GYO Kiyofumi (00108383)

# of Collaborated Projects: 9 results

# of Collaborated Products: 19 results
2. HAKUBA Nobuhiro (70304623)

# of Collaborated Projects: 6 results

# of Collaborated Products: 17 results
3. SNINOMORI Yusuke (60335908)

# of Collaborated Projects: 5 results

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6. HYODO Jun (30423453)

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7. WAKISAKA Hiroyuki (30304611)

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HATO Naohito 羽藤 直人

Research Projects

Research Products

Co-Researchers

加齢性難聴における水素ガスの予防効果とその分子機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

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Development of a novel treatment for severe facial nerve palsy by intratympanic administration of sustained-release neurotrophic factorPrincipal Investigator

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Development of a new treatment for sequelae of facial nerve palsyPrincipal Investigator

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Expression of Galectin-7 in cholesteatoma matrix and its clinical significancePrincipal Investigator

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RNA expression in facial muscle following damage to the facial nerve -As a tool of early prognostic diagnosis-Principal Investigator

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Treatment of facial nerve synkinesis by basic fibroblast growth factor impregnated in a biodegradable hydrogelPrincipal Investigator

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HATO Naohito 羽藤直人