Sakiyama Shoji 先山正二

… Alternative Names

SAKIYAMA Shoji 先山正二

SEKIYAMA Syoji 先山正二

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Researcher Number	60291986
Other IDs
Affiliation (Current)	2025: 独立行政法人国立病院機構高知病院(臨床研究部), 副院長室, 副院長
Affiliation (based on the past Project Information) *help	2016 – 2018: 徳島大学, 大学院医歯薬学研究部(医学系), 准教授 2016: 独立行政法人国立病院機構高知病院(臨床研究部), 副院長室, 副院長 2015: 徳島大学, 大学院医歯薬学研究部, 准教授 2011 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 准教授 2008 – 2010: The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 准教授 … More 2006: The University of Tokushima, Institute of Health Biosciences, Senior assistant Professor, 大学院ヘルスバイオサイエンス研究部, 講師 2005: 徳島大学, 医学部・歯学部附属病院, 講師 2003: University of Tokushima, University hospital, senior assistant professor, 医学部・歯学部附属病院, 講師 1997 – 2002: 徳島大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Thoracic surgery / Thoracic surgery / Respiratory surgery Except Principal Investigator Thoracic surgery / Respiratory surgery
Keywords	Principal Investigator rat / lung transplantation / ラット / 肺移植 / 豚 / ERK / mitogen-activated protein kinase / protein tyrosine phosphorylation / preservation / ischemia-reperfusion … More / reperfusion / chronic rejection / 慢性拒絶反応 / TCR / 肺線維症 / ステロイド / 肺の再生 / 胎仔肺移植 / 胎生期肺組織 / 胎生期肺 / 肺組織移植 / 移植 / bleomycine / pulmonary fibrosis / transplantation / fetal lung / fetal lung tissue / lung / lung regeneration / 組織修復 / 再生 / ブレオマイシン / 胎仔肺 / 胎児肺組織移植 / 胎仔肺組織移植 / 肺 / 肺再生 / protein tyrosine phosphatase / protein tyrosine kinase / 拒絶反応 / ドナー骨髄細胞 / 胸腺内移植 / ラット同所性肺移植 / ラット肺移植 / immunosuppression / acute rejection / TCR V-BETA / TCRV-beta / TCRVbeta / 免疫抑制 / 急性拒絶反応 / TCR V / マウス / 肺気腫 / 胎生期肺移植 / 再生医学 / 肺の分化 / 肺の発生 / 肺組織 / 免疫抑制剤 / 肺の発生分化 / 経気道的投与 / 再生医療 / 呼吸器外科学 … More Except Principal Investigator 肺癌 / lung cancer / Haptoinvasion assay / MM1-166 / BPHA / 終末細気管支障害 / 気道内投与 / 急性肺障害 / 終末気管支障害 / 気管支肺胞幹細胞 / iPS細胞 / operation sample / RNA expression / DNA microarray / metastatic pattern / orthotopic implantation model / primary cultured cancer cell / 抗癌剤感受性試験 / 肺癌初代培養 / 同所移植モデル / 転移様 / 同所性移植 / 手術検体 / 遺伝子変化 / DNAマイクロアレイ / 転移様式 / 同所性移植モデル / 初代培養癌細胞 / accumulation of chromium / squamous cell caarcinoma / rat / chromate lung cancer / Chromium / クロム酸塩 / クロム肺癌 chromate Lung cancer / 中枢性肺扁平上皮癌 / クロム蓄積量 / 中枢性肺偏平上皮癌 / ラット / ヒトクロム肺癌 / クロム / tumor invasion / MMP inhibitor / in vitro invasion assay / 浸潤阻害 / MMP-2 / MMI-166 / 浸潤能 / メタロ・プロテナーゼ / 自家蛍光 / 5-ALA / 蛍光診断 / 胸膜浸潤 Less

Intratracheal administration of induced pluripotent stem (iPS) cells induced bronchioloalveolar stem cells (BASCs) can accelerate the repair of injured lung.
- Principal Investigator
  
  TOBA Hiroaki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  The University of Tokushima
Fetal lung fragments implantation into fibrotic lung of a pig modelPrincipal Investigator
- Principal Investigator
  
  SAKIYAMA Shoji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kochi National Hospital
  The University of Tokushima
Autofluorescence diagnosis of visceral pleural invasion and demonstration of the subpleural pathway of lymph node metastasis in patients with non-small cell lung cancer.
- Principal Investigator
  
  TAKIZAWA Hiromitsu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  The University of Tokushima
Experimental examination of the pulmonary emphysema treatment with fetal lung tissues transplantation - a pig emphysema model -Principal Investigator
- Principal Investigator
  
  SAKIYAMA Shoji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  The University of Tokushima
Implantation of fetal pig lung fragments into adult rat lung parenchyma-search for a possibility of transbronchial delivery with a bronchoscope-Principal Investigator
- Principal Investigator
  
  SAKIYAMA Shoji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  The University of Tokushima
Lung regeneration : implantation of fetal rat lung fragments into adult rat lung with bleomycine induced fibrosisPrincipal Investigator
- Principal Investigator
  
  SEKIYAMA Syoji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  The University of Tokushima
Activation of ERK during ischemia-reperfusion in lung transplantation.Principal Investigator
- Principal Investigator
  
  SAKIYAMA Shoji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  THE University of Tokushima
Establishment of patient-like SCID mouse model by orthotopically implanting primary cultured cells from surgically-resected lung cancer tissues.
- Principal Investigator
  
  MONDEN Yasumasa
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  THE University of Tokushima
The Elucidation of Carcinogenesis in Squamous Cell Carcinoma of the Lung Using Chromate-Induced Lung Cancer of the Rat
- Principal Investigator
  
  MONDEN Yasumasa
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  The University of Tokushima
Induction of microchimerisim and attenuation of chronic rejection in lung transplantationPrincipal Investigator
- Principal Investigator
  
  SHOJI Sakiyama
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  The university of Tokushima
MMP inhibitor BPHA inhibit the potential of tumor growth and metastasis in human lung cancer cell lin
- Principal Investigator
  
  KONDO Kazuya
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  The university of Tokushima
IMMUNOSUPPRESSION WITH ANTI-T CELL RECEPTOR V-BETA ANTIBODY IN LUNG TRANSPLANTATONPrincipal Investigator
- Principal Investigator
  
  SAKIYAMA Shoji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  The university of Tokushima

All 2016 2015 2014 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Lung regeneration by fetal lung tissue implantation in a mouse pulmonary emphysema model2016
- Author(s)
  Uyama K, Sakiyama S, Yoshida M, MD, Kenzaki K, Toba H, Kawakami Y, Okumura K, Takizawa H, Kondo K and Tangoku A.
- Journal Title
  
  J Med Invest
  
  Volume: 63
- NAID
  130005245852
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462127
[Journal Article] 肺癌の術中胸膜浸潤診断の正確性についての検討2015
- Author(s)
  滝沢宏光、坪井光弘、梶浦耕一郎、鳥羽博明、中川靖士、川上行奎、吉田光輝、先山正二、近藤和也、森下敦司、河北直也、広瀬敏幸
- Journal Title
  
  日本呼吸器外科学会誌
  
  Volume: 29 Pages: 576-581
- NAID
  130005090335
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25462178
[Journal Article] Implantation of fetal rat lung fragments into bleomycin-induced pulmonary fibrosis2012
- Author(s)
  Toba H, Sakiyama S, Koichiro kenzaki, Yukikiyo kawakami, Koh Uyama, Yoshimi Bando, Akira Tangoku
- Journal Title
  
  J Thorac Cardiovasc Surg
  
  Volume: vol.143 Pages: 1429-1435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592062
[Journal Article] Implantation of fetal rat lung fragments into bleomycin-induced pulmonary fibrosis.2012
- Author(s)
  Toba H, Sakiyama S, et al.
- Journal Title
  
  J Thorac Cardiovasc Surg.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592062
[Presentation] 胸膜の自家蛍光減弱は肺癌の浸潤性を反映する2015
- Author(s)
  滝沢宏光、近藤和也、乾　友浩、髙杉　遥、松本大資、河北直也、西野豪志、坪井光弘、梶浦耕一郎、鳥羽博明、川上行奎、吉田光輝、先山正二、丹黒　章
- Organizer
  第56回日本肺癌学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-25462178
[Presentation] The Correlation between Visceral Pleural Invasion in T1a Non-Small Lung Cancer and Lymph Node Metastasis2015
- Author(s)
  Mitsuhiro Tsuboi, Hiromitsu Takizawa, Daisuke Matsumoto, Naoya Kawakita, Koichiro Kajiura, Hiroaki Toba, Yukikiyo Kawakami, Shoji Sakiyama, Kazuya Kondo, Akira Tangoku
- Organizer
  16th World Conference on Lung Cancer
- Place of Presentation
  Denver, Colorado(USA)
- Year and Date
  2015-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462178
[Presentation] Computed Tomography Lymphography by Transbronchial Injection of Iopamidol for Preoperative Non-Small Cell Lung Cancer Patients2015
- Author(s)
  Hiromitsu Takizawa, Kazuya Kondo, Mitsuhiro Tsuboi, Koichiro Kajiura, Tamaki Otani, Hiroaki Toba, Yukikiyo Kawakami, Shoji Sakiyama, Akira Tangoku
- Organizer
  16th World Conference on Lung Cancer
- Place of Presentation
  Denver, Colorado(USA)
- Year and Date
  2015-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462178
[Presentation] 肺癌区域切除におけるリンパ節転移と胸膜浸潤の術中診断精度向上に向けた取り組み2014
- Author(s)
  滝沢宏光、近藤和也、梶浦耕一郎、坪井光弘、鳥羽博明、中川靖士、吉田光輝、川上行奎、先山正二、丹黒　章
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  国立京都国際会館、グランドプリンスホテル京都（京都府）
- Data Source
  KAKENHI-PROJECT-25462178
[Presentation] 自家蛍光観察による胸膜浸潤の術中診断精度向上にむけた取り組み2014
- Author(s)
  滝沢宏光、近藤和也、梶浦耕一郎、坪井光弘、森下敦司、鳥羽博明、中川靖士、吉田光輝、川上行奎、先山正二、丹黒　章
- Organizer
  第37回日本呼吸器内視鏡学会学術集会
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-25462178
[Presentation] 肺の再生・修復を目的とした胎生期肺組織移植2012
- Author(s)
  先山正二、監崎孝一郎、鳥羽博明、宇山攻、梶浦耕一郎、中川靖士、吉田光輝、川上行奎、滝沢宏光、近藤和也、丹黒章
- Organizer
  第29回日本呼吸器外科学会総会
- Place of Presentation
  秋田キャッスルホテル(秋田県)
- Data Source
  KAKENHI-PROJECT-23592062
[Presentation] 胎仔肺移植による肺気腫自然発症モデルマウス肺修復の試み2011
- Author(s)
  宇山　攻、先山正二　他4名
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  東京都（紙上開催）
- Data Source
  KAKENHI-PROJECT-23592062
[Presentation] 胎仔肺移植による肺気腫自然発症モデルマウス肺修復の試み2011
- Author(s)
  宇山攻、先山正二、鳥羽博明、吉田光輝、監崎孝一郎、丹黒章
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23592062
[Presentation] 豚を用いた胎生期肺組織移植の実験的検討2010
- Author(s)
  先山正二, 監崎孝一郎, 鳥羽博明, NarmisheekhKhasag, 宇山攻, 中川靖士, 滝沢宏光, 近藤和也, 丹黒章
- Organizer
  日本外科学会雑誌(0301-4894)111巻臨増2Page648
- Data Source
  KAKENHI-PROJECT-20591672
[Presentation] 豚を用いた胎生期肺組織移植の実験的検討ラットで得られた知見との比較を含めて2010
- Author(s)
  先山正二, 監崎孝一郎, 鳥羽博明, NarmisheekhKhasag, 宇山攻, 中川靖士, 滝沢宏光, 近藤和也, 丹黒章
- Organizer
  日本呼吸器外科学会雑誌(0919-0945)24巻3号Page417
- Data Source
  KAKENHI-PROJECT-20591672
[Presentation] Sex-mismatchを用いたラット胎仔肺移植モデルのドナー細胞の組織学的検討2010
- Author(s)
  監崎孝一郎, 先山正二, 宇山攻, 鳥羽博明, 中川靖士, 滝沢宏光, 近藤和也, 丹黒章
- Organizer
  日本外科学会雑誌(0301-4894)111巻臨増2Page210
- Data Source
  KAKENHI-PROJECT-20591672
[Presentation] 豚を用いた胎生期肺組織移植の実験的検討2010
- Author(s)
  先山正二
- Organizer
  第110回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2010-04-10
- Data Source
  KAKENHI-PROJECT-20591672
[Presentation] 呼吸器外科領域の再生医療ブレオマイシン誘導肺線維症モデルに対する胎仔肺組織移植2009
- Author(s)
  鳥羽博明, 先山正二, 監崎孝一郎, 中川靖士, 滝沢宏光, 近藤和也, 丹黒章
- Organizer
  日本呼吸器外科学会雑誌(0919-0945)23巻3号Page350
- Data Source
  KAKENHI-PROJECT-20591672
[Presentation] GFPラットを用いた胎仔肺移植モデルのドナー組織間再融合の組織学的検討2008
- Author(s)
  監崎孝一郎, 先山正二, 宇山攻, 松岡永, 鳥羽博明, 滝沢宏光, 広瀬由紀子, 近藤和也, 坂東良美, 丹黒章
- Organizer
  日本外科学会雑誌(0301-4894)109巻臨増2Page213
- Data Source
  KAKENHI-PROJECT-20591672
[Presentation] 胎生期肺組織移植における気道系の分化とbranchingに関する検討
- Author(s)
  先山正二、鳥羽博明、監崎孝一郎、坪井光弘、梶浦耕一郎、中川靖士、吉田光輝、川上行奎、滝沢宏光、近藤和也、丹黒章
- Organizer
  第37回日本呼吸器内視鏡学会学術集会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-04-14 – 2014-04-15
- Data Source
  KAKENHI-PROJECT-26462127
[Presentation] Lung regeneration: Glucocorticoid administration facilitates differentiation of rat fetal lung fragments into adult rat lung parenchyma.
- Author(s)
  S. Sakiyama, M. Yoshida, Y. Kawakami, K Kenzaki, M. Tsuboi, K. Kajiura, Y. Nakagawa, H. Takizawa, K. Kondo, A. Tangoku
- Organizer
  The 2014 American Thoracic Society International Conference
- Place of Presentation
  San Diego Convension Center（San Diego,USA）
- Year and Date
  2014-05-16 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-26462127
[Presentation] 肺の再生・修復を目的とした胎生期肺組織移植
- Author(s)
  先山正二
- Organizer
  第29回日本呼吸器外科学会総会
- Place of Presentation
  秋田キャッスルホテル（秋田県）
- Data Source
  KAKENHI-PROJECT-23592062

1. KONDO Kazuya (10263815)

# of Collaborated Projects: 8 results

# of Collaborated Products: 6 results
2. TOBA Hiroaki (40403745)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
3. MONDEN Yasumasa (60028628)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. KENZAKI Koichirou (70325265)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
5. TAKIZAWA HIromitsu (90332816)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
6. KAWAKAMI Yukikiyo (00596249)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
7. KAJIURA Koichiro (60596253)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
8. YOSHIDA Mitsuteru (30403710)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
9. MIYOSHI Takanori (20346612)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. 谷田信行 (20311821)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KOMAKI Kansei (60215382)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 宇山攻 (90437658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 坪井光弘 (10711872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 沖津宏 (50214036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 日野弘之

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sakiyama Shoji 先山 正二

SAKIYAMA Shoji 先山 正二

SEKIYAMA Syoji 先山 正二

Research Projects

Research Products

Co-Researchers

Intratracheal administration of induced pluripotent stem (iPS) cells induced bronchioloalveolar stem cells (BASCs) can accelerate the repair of injured lung.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Fetal lung fragments implantation into fibrotic lung of a pig modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Autofluorescence diagnosis of visceral pleural invasion and demonstration of the subpleural pathway of lymph node metastasis in patients with non-small cell lung cancer.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental examination of the pulmonary emphysema treatment with fetal lung tissues transplantation - a pig emphysema model -Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Implantation of fetal pig lung fragments into adult rat lung parenchyma-search for a possibility of transbronchial delivery with a bronchoscope-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Lung regeneration : implantation of fetal rat lung fragments into adult rat lung with bleomycine induced fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Activation of ERK during ischemia-reperfusion in lung transplantation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of patient-like SCID mouse model by orthotopically implanting primary cultured cells from surgically-resected lung cancer tissues.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Elucidation of Carcinogenesis in Squamous Cell Carcinoma of the Lung Using Chromate-Induced Lung Cancer of the Rat

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Induction of microchimerisim and attenuation of chronic rejection in lung transplantationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

MMP inhibitor BPHA inhibit the potential of tumor growth and metastasis in human lung cancer cell lin

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IMMUNOSUPPRESSION WITH ANTI-T CELL RECEPTOR V-BETA ANTIBODY IN LUNG TRANSPLANTATONPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Lung regeneration by fetal lung tissue implantation in a mouse pulmonary emphysema model2016

Author(s)

Sakiyama Shoji 先山正二

SAKIYAMA Shoji 先山正二

SEKIYAMA Syoji 先山正二

[Presentation] 豚を用いた胎生期肺組織移植の実験的検討ラットで得られた知見との比較を含めて2010