TAKAHASHI Kazuma 高橋和眞

… Alternative Names

高橋和真タカハシカズマ

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Researcher Number	60292215
Other IDs
External Links
Affiliation (Current)	2022: 岩手県立大学, 看護学部, 教授
Affiliation (based on the past Project Information) *help	2007: Iwate Medical University, 医学部, Lecturer 2006: 東北大学, 付属病院, 助手 2005 – 2006: 東北大学, 病院, 助手 2004 – 2006: Tohoku University, Hosipital, Research Associate, 病院・助手 2004 – 2005: Tohoku University, Tohoku University Hospital, Assistant Professor, 助手 … More 2002 – 2003: 東北大学, 医学部付属病院, 助手 2002 – 2003: Tohoku University Hospital, Department of Diabetes and Metabolism, Research Associate, 医学部附属病院, 助手 2000 – 2002: 東北大学, 医学部・附属病院, 助手 1999: Graduate Medical School, Tohoku University, Research Associate, 大学院・医学系研究科, 助手 1998: 東北大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator 内科学一般 / Metabolomics / Metabolomics Except Principal Investigator Metabolomics / Metabolomics
Keywords	Principal Investigator 1型糖尿病 / 樹状細胞 / 抗原提示細胞 / NODマウス / dendritic cells / CD204 / Thバランス / CD86 / Th1 / Th2バランス … More / ケモカイン / サイトカイン / I型糖尿病 / マイクロアレイ / トランスクリプトーム / トランスグリプトーム / type I diabetes mellitus / non-obese diabetic mice / trascriptome / スカベンジャー受容体 / type 1 diabetes mellitus / Macrophage scavenger receptor … More Except Principal Investigator 糖尿病 / TNF-α / NIDDM / CFA / GTT / UCP-2 / インスリン / WFS1 / endoplasmic reticulum / Diabetes / Insulin / AP-18 / ピオグリタゾン / Pioglitazone / RNA干渉 / 肝細胞 / ノックダウン法 / 2型糖尿病 / KK-Ayマウス / IL-1 / type 2 diabetes / KK-Ay mouse / 膵β細胞 / ウオルフラム症候群 / 小胞体 / ノックアウトマウス / アポトーシス / 小胞体ストレス / ER(endoplasmic reticulum) / インスリン分泌 / 視神経萎縮 / pancreatic β cell / Wolfram syndrome / knock-out mice / 遺伝子多型 / 糖尿病合併症 / 糖尿病神経障害 / 糖尿病腎症 / 動脈硬化症 / SNPs / diabetic complications / diabetic neuropathy / diabetic nephropathy / arteriosclerosis / 肥満 / メタボリック症候群 / インスリン抵抗性 / 遺伝子治療 / diabetes / obesity / metabolic syndrome / insulin resistance / gene therapy / 脂肪細胞 / アディポネクチン / 糖輸送担体-4 / グリクラジド / グリベンクラミド / IL-1β / IL-6 / レプチン / GLUT4 / グリクラシド / デラプリル / Adipocytes / Adiponectin / TNF-aloha / Glucose transnorter-4 / Gliclazide / Glibenclamide / ウロテンシンII / 副交感神経 / 一酸化窒素 / 肝臓 / 遺伝子ノックダウン / Urotensin II / Parasympatic nerve / Nitric Oxide / Liver / Gene knockdown / 1型糖尿病 / チアゾリジン誘導体 / ピオグルタゾン / 樹状細胞 / NODマウス / 緩徐進行型1型糖尿病 / NKT細胞 / チアゾリン誘導体 / 液体食事負荷試験 / Type 1 diabetes / Thiazolidine derivative / Dendritic cells / NOD mouse Less

A unique CD204^+ subpopulation of dendritic cells in NOD micePrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Kazuma
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Signaling axis of urotensin II, parasympathetic nerves, and nitric oxide on carbohydrate metabolism: A clinical
- Principal Investigator
  
  TAMURA Akira
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Research of prevention of type 1 diabetes by thiazolidine derivative.
- Principal Investigator
  
  NAGATA Masao
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kobe University
肝インスリンシグナルの個体糖脂質代謝における役割-ノックダウン法を用いての解析-
- Principal Investigator
  
  KATAGIRI Hedeki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Development of gene therapy for diabetes associated with obesity
- Principal Investigator
  
  KATAGIRI Hideki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Screening of clinical medicines for effects on gene expressions and protein productions of adipocytokines by using a newly-isolated preadipocyte line
- Principal Investigator
  
  SATOH Jo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Iwate Medical University
Gene expression profiling of marrow-derived dendritic cells from non-obese diabetic micePrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Kazuma
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  TOHOKU UNIVERSITY
自己免疫性1型糖尿病患者の抗原提示細胞の異常の解析とその正常化による治療法の開発Principal Investigator
- Principal Investigator
  
  高橋和眞 (高橋和真)
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  Tohoku University
Generation of Wolfram syndrome mice, aiming at development of new therapeutics for diabetes through preserving pancreatic beta cells
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
  Yamaguchi University
Study on associations of novel TNF-α promoter polymorphisms with diabetes and diabetic complications
- Principal Investigator
  
  SATOH Jo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
樹状細胞を用いた膵β細胞抗原特異的調節性T細胞の誘導と1型糖尿病の予防的治療Principal Investigator
- Principal Investigator
  
  高橋和眞 (高橋和真)
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
Expression of UCP-2 and UCP-3 genes in obese type 2 diabetes mellitus and its modification by a cytokine inducer
- Principal Investigator
  
  SATOH Jo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  TOHOKU UNIVERSITY

All 2007 2006 2005

All Journal Article Presentation

[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007
- Author(s)
  Takahashi R, Ishihara H, et al.
- Journal Title
  
  J Mol Endocrinol. 38・1
  
  Pages: 127-136
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007
- Author(s)
  Takahashi R, Ishihara H, et al.
- Journal Title
  
  J Mol Endocrinol 38・1
  
  Pages: 127-136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007
- Author(s)
  Takahashi R, Ishihara H, Takahashi K, Tamura A, Yamaguchi S, Yamada T, Katagiri H, Oka Y.
- Journal Title
  
  J Mol Endocrinol. 38(1):
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Lack of association between IBD5 and Crohn's disease in Japanese patients demonstrates population-specific differences in inflammatory bowel disease.2006
- Author(s)
  Tosa M, Negoro K, Kinouchi Y, Abe H, Nomura E, Takagi S, Aihara H, Oomori S, Sugimura M, Takahashi K, et al.
- Journal Title
  
  Scand J Gastroenterol. 41・1
  
  Pages: 48-53
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Lack of association between IBD5 and Crohn's disease in Japanese patients demonstrates population-specific differences in inflammatory bowel disease2006
- Author(s)
  Tosa M, Negoro K, Kinouchi Y, Abe H, Nomura E, Takagi S, Aihara H, Oomori S, Sugimura M, Takahashi K, et al.
- Journal Title
  
  Scand J Gastroenterol. 41・1
  
  Pages: 48-53
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] 糖尿病モデル動物 1型モデル免疫モデル動物に学ぶ1型糖尿病の免疫学2006
- Author(s)
  高橋和眞
- Journal Title
  
  Diabetes Frontier 17
  
  Pages: 397-403
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Lack of association between IBD5 and Crohn's disease in Japanese patients demonstrates population-specific differences in inflammatory bowel disease2006
- Author(s)
  Tosa M, Negoro K, Kinouchi Y, Abe H, Nomura E, Takagi S, Aihara H, Oomori S, Sugimura M, Takahashi K, et al.
- Journal Title
  
  Scand J Gastroenterol. 41(1)
  
  Pages: 48-53
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets.2006
- Author(s)
  Takahashi R, Ishihara H, Ct al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 290・2
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets.2006
- Author(s)
  Takahashi R, Ishihara H, et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 290・2
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590912
[Journal Article] 【対論糖尿病診療】インスリンアナログの有用性Consアナログ製剤の特性を熟知して患者さんに最適な製剤を選択する.2006
- Author(s)
  高橋和眞, 種田嘉信, 小野利夫
- Journal Title
  
  糖尿病診療マスター 4
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Lack of association between IBD5 and Crohn's disease in Japanese patients demonstrates population-specific differences in inflammatory bowel disease.2006
- Author(s)
  Tosa M, Negoro K, Kinouchi Y, Abe H, Nomura E, Takagi S, Aihara H, Oomori S, Sugimura M, Takahashi K, Hiwatashi N, Takahashi S, Shimosegawa T.
- Journal Title
  
  Scand J Gastroenterol 41(1):
  
  Pages: 48-53
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Curcuminoids and sesquiterpenoids in turmeric (Curcuma longa L.) suppress an increase in blood glucose level in type 2 diabetic KK-Ay mice.2005
- Author(s)
  Nishiyama T, Mae T, Kishida H, Tsukagawa M, Mimaki Y, Kuroda M, Sashida Y, Takahashi K, et al.
- Journal Title
  
  J Agric Food Chem. 53・4
  
  Pages: 959-963
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Secondary sulfonylurea failure : comparison of period until insulin treatment between diabetic patients treated with gliclazide and glibenclamide.2005
- Author(s)
  Satoh J, Takahashi K, et al.
- Journal Title
  
  Diabetes Res Clin Pract. 70・3
  
  Pages: 291-297
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Secondary sulfonylurea failure : comparison of period until insulin treatment between diabetic patients treated with gliclazide and glibenclamide2005
- Author(s)
  Satoh J, Takahashi K, et al.
- Journal Title
  
  Diabetes Res Clin Pract. 70・3
  
  Pages: 291-7
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Hypoglycemic effects of turmeric(Curcuma longa L.rhizomes)on genetically diabetic KK-Ay mice2005
- Author(s)
  Kuroda M, Mimaki Y, Nishiyama T, Mae T, Kishida H, Tsukagawa M, Takahashi K, et al.
- Journal Title
  
  Biol Pharm Bull. 28(5)
  
  Pages: 937-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Hypoglycemic effects of turmeric(Curcuma longa L. rhizomes)on genetically diabetic KK-Ay mice2005
- Author(s)
  Kuroda M, Mimaki Y, Nishiyama T, Mae T, Kishida H, Tsukagawa M, Takahashi K, et al
- Journal Title
  
  Biol Pharm Bull. 28・5
  
  Pages: 937-9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Secondary sulfonylurea failure : comparison of period until insulin treatment between diabetic patients treated with gliclazide and glibenclamide2005
- Author(s)
  Satoh J, Takahashi K, et al.
- Journal Title
  
  Diabetes Res Clin Pract. 70(3)
  
  Pages: 291-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Curcuminoids and sesquiterpenoids in turmeric(Curcuma longa L.)suppress an increase in blood glucose level in type 2 diabetic KK-Ay mice2005
- Author(s)
  Nishiyama T, Mae T, Kishida H, Tsukagawa M, Mimaki Y, Kuroda M, Sashida Y, Takahashi K, et al.
- Journal Title
  
  J Agric Food Chem. 53・4
  
  Pages: 959-63
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Curcuminoids and sesquiterpenoids in turmeric(Curcuma longa L.)suppress an increase in blood glucose level in type 2 diabetic KK-Ay mice2005
- Author(s)
  Nishiyama T, Mae T, Kishida H, Tsukagawa M, Mimaki Y, Kuroda M, Sashida Y, Takahashi K, et al.
- Journal Title
  
  J Agric Food Chem. 53(4)
  
  Pages: 959-63
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590911
[Journal Article] Hypoglycemic effects of turmeric (Curcuma longa L. rhizomes) on genetically diabetic KK-Ay mice.2005
- Author(s)
  Kuroda M, Mimaki Y, Nishiyama T, Mae T, Kishida H, Tsukagawa M, Takahashi K, et al.
- Journal Title
  
  Biol Pharm Bull. 28・5
  
  Pages: 937-939
- Data Source
  KAKENHI-PROJECT-17590911
[Presentation] Type 2 arginase gene promoter microsatellite polymorphism influences development of type 1 diabetes mellitus in Japanese2005
- Author(s)
  Takahashi K, Maruyama T, Shimada A, Kinouchi Y, Suzukin S, Shimosegawa T, Satoh J, Oka Y.
- Organizer
  The 41^<th> European Association of Study on Diabetes Annual Meeting
- Place of Presentation
  Athens, Greece
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590911
[Presentation] Type 2 arginase gene promoter microsatellite polymorphism influences development of type 1 diabetes mellitus in Japanese2005
- Author(s)
  Takahashi K, Maruyama T, Shimada A, Kinouchi Y, Suzukin S, Shimosegawa T, Satoh J, Oka Y.
- Organizer
  The Joint Meeting of the 8^<th> Congress of Immunology of Diabetes Society and the 3^<rd> Congress of Japanese Society of Type 1 Diabetes
- Place of Presentation
  Awaji, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590911

1. SATOH Jo (60125565)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. KATAGIRI Hedeki (00344664)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. HINOKIO Yoshinori (10282071)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. ISHIHARA Hisamitsu (60361086)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
5. ISHIGAKI Yasushi (50375002)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TAMAGAWA Akira (80188416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OKA Yoshitomo (70175256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HIRAI Masashi (80312578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. DOI Hideyuki (90188839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KANEKO Yoshihito (80285585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ISHIDA Wataru (80305995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ISHI Naoto (60291267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
13. TAMURA Akira (00375023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SUZUKI Susumu (70216399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAGATA Masao (70294220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YOKONO Koichi (50144580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MORIYAMA Hiroaki (70372646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAKAMURA Masato (40227921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KAWAMURA Tomoyuki (60271186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 谷澤幸生 (00217142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 湯尻俊昭

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 佐々木輝昌

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 竹田孔明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 松本健

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAKAHASHI Kazuma 高橋 和眞

高橋 和真 タカハシ カズマ

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A unique CD204^+ subpopulation of dendritic cells in NOD micePrincipal Investigator

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Gene expression profiling of marrow-derived dendritic cells from non-obese diabetic micePrincipal Investigator

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自己免疫性1型糖尿病患者の抗原提示細胞の異常の解析とその正常化による治療法の開発Principal Investigator

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樹状細胞を用いた膵β細胞抗原特異的調節性T細胞の誘導と1型糖尿病の予防的治療Principal Investigator

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[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Efficient and controlled gene expression in mouse pancreatic islets by arterial delivery of tetracycline-inducible adenoviral vectors.2007

TAKAHASHI Kazuma 高橋和眞

高橋和真タカハシカズマ

[Journal Article] 糖尿病モデル動物 1型モデル免疫モデル動物に学ぶ1型糖尿病の免疫学2006

[Journal Article] 【対論糖尿病診療】インスリンアナログの有用性Consアナログ製剤の特性を熟知して患者さんに最適な製剤を選択する.2006