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TOYONAGA Tetsushi  豊永 哲至

ORCIDConnect your ORCID iD *help
Researcher Number 60295128
External Links
Affiliation (based on the past Project Information) *help 2006: Kumamoto University, Faculty of Medical and Phamaceutical Scienc es, Assistant Professor, 大学院医学薬学研究部, 講師
2005: 熊本大学, 大学院医学薬学研究部, 助手
2003 – 2005: 熊本大学, 大学院・医学薬学研究部, 助手
1997 – 2002: 熊本大学, 医学部, 助手
1999: 熊本大学, 医学部・附属病院, 助手
Review Section/Research Field
Principal Investigator
Metabolomics
Except Principal Investigator
Metabolomics / Biomedical engineering/Biological material science / Biomedical engineering/Biological material science / Metabolomics / 内分泌・代謝学 / Biological Sciences
Keywords
Principal Investigator
トランスジェニックマウス / Manganese superoxide dismutase / 8-hydroxydeoxyguanosine / Mitochondria / Oxidative stress / Diabetic complications / 活性酸素 / 血管合併症 / 糖尿病 / マンガネーゼスーパーオキサイドジスムターゼ … More / 8-ハイドロキシデオキシグアノシン / ミトコンドリア / 酸化ストレス / 糖尿病性合併症 / トランスジンニックマウス / アポトーシス / インターフェロンガンマ / インスリン依存型糖尿病 … More
Except Principal Investigator
IRS-1 / 膵β細胞 / インスリン分泌 / 糖尿病 / 人工膵島 / obesity / ノックアウトマウス / 肥満 / GM-CSF / マクロファージ / インスリン受容体 / インスリン / CaM kinase II / insulin secretion / pancreatic beta cell / CaMキナーゼII / multivariate analysis / haemoglobin A1C / blood glucose measurement / non-invasive measuring system / 多変量解析 / ヘモグロビンA_<1c> / 血糖計測 / 非侵襲計測システム / strict glucose regulation / insulin infusion pump / artificial endocrine pancreas / needle-type glucose sensor / 過酸化水素電極 / センサ出力 / 血糖連続計測システム / ブドウ糖センサ / ポリイミド / 携帯型人工膵島 / 血糖制御 / インスリンポンプ / 針型ブドウ糖センサ / Pancreatic β-cell / Endoplasmic Reticulum Stress / Oxidative Stress / Diabetes Mellitus / Bip / Mn-SOD / ERストレス / ミトコンドリアROS / 小胞体ストレス / 細胞内ラジカル / INHIBITORY PROTEIN / PROMOTER ANALYSIS / KNOCKOUT MOUSE / INSULIN SECRETION / CALMODULIN / CALCIUM / PANCREATIC BETA CELLS / Cre recombinase / 阻害蛋白CaMKIIN / プロモーター解析 / カルモデュリン / カルシウム / diabetes mellitus / insulin resistance / インスリン抵抗性 / Chalcogenide optical fiber / Attenuated total reflection (ATR) prism / Fourier-transform infrared spectroscopy / Non-invasive blood glucose measurement / 近赤外拡散反射光 / 近赤外透過光 / フーリエ変換赤外分光光度計 / 減衰全反射プリズム / カルコゲナイド光ファイバー / 非侵襲的血糖計測法 / Needle-Type Glucose Sensor / Artificial Endocrine Pancreas / Glucose Concentration / Telemetry Glucose Monitoring System / 微小針型ブドウ糖センサ / ブドウ糖 / テレメトリー・システム / knock-out mouse / protein tyrosin phosphatase / bradykinin / insulin receptor / insulin / チロシンフォスファターゼ / ブラジキニン / Protein kinase C / Oxidized low density lipoprotein / Scavenger receptor / Atherosclerosis / Cell proliferation / Foam Cell / Macrophage / lysophohsphatidylcholine / protein kinase C / 酸化LDL / スカベンジャー受容体 / 動脈硬化 / 細胞増殖 / 泡沫細胞 / AICAR / 脂肪細胞 Less
  • Research Projects

    (13 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (13 People)
  •  Development of near-infrared measuring system for blood glucose and haemoglobin A1c

    • Principal Investigator
      NISHIDA Kenro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Kumamoto University
  •  Regulation of pancreatic・cell function by Ca2+/calmodulin-dependent protein kinase II delta.-Analysis using CaM-KIIN, noble inhibitory protein, and constitutive active CaM kinase II-

    • Principal Investigator
      TSURUZOE Kaku
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  脂肪細胞におけるインスリン作用伝達分子の発現調節と生体機能制御における意義

    • Principal Investigator
      ARAKI Eiichi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Analysis of the mechanisms of pancreatic β-cells destruction by intra-cellular oxidative stress and endoplasmic reticulum stress, and its application for the diabetes treatment.

    • Principal Investigator
      ARAKI Eiichi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  DEVELOPMENT OF A HIGHLY RESPONSIVE NEEDLE-TYPE GLUCOSE SENSOR USING POLYIMIDE FOR A WEARABLE ARTIFICIAL ENDOCRINE PANCREAS

    • Principal Investigator
      SAKAKIDA Michiharu
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  FUNCTIONAL ANALYSIS OF CA/CALMODULIN-DEPENDENT PROTEIN KINASE II IN PANCREATIC BETS-CELLS WITH CONDITIONAL KNOCKOUT MICE.

    • Principal Investigator
      MATSUMOTO Kazuya
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  The role of mitochondria-derived reactive oxygen species in the pathogenesis of diabetic complicationsPrincipal Investigator

    • Principal Investigator
      TOYONAGA Tetsushi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  Molecular mechanisms of insulin resistance in obesity-induced IRS-1 heterozygous knockout mice.

    • Principal Investigator
      ARAKI Eiichi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  DEVELOPMENT OF NON-INVASIVE BLOOD GLUCOSE MEASUREMENT BY FOURIER TRANSFORM INFRARED SPECTROSOPIC ANALYSIS THROUGH THE MUCOUS MEMBRANE OF THE LIP USING CHALCOGENIDE OPTICAL FIBER SYSTEM

    • Principal Investigator
      SAKAKIDA Michiharu, 七里 元亮
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  インスリン依存型糖尿病発症と膵β細胞におけるアポトーシスPrincipal Investigator

    • Principal Investigator
      豊永 哲至
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  Molecular and developmental biological analysis of impact of genetic and environmental factors on the development of insulin resistance

    • Principal Investigator
      ARAKI Eiichi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  DEVELOPMENT AND CLINICAL APPLICATION OF IMPLANTABLE WEARABLE ARTIFICIAL ENDOCRINE PANCREAS WITH A TELEMETRY GLUCOSE MONITORING SYSTEM

    • Principal Investigator
      SAKAKIDA Michiharu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Intracellular signal-transduction in oxidized LDL-induced macrophage growth in arterial wall.

    • Principal Investigator
      SHICHIRI Motoaki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Kumamoto University

All 2005

All Journal Article

  • [Journal Article] Enhanced expression of PDX-1 and Ngn3 by exending-4 during β cell regeneration in STZ-treated mice.2005

    • Author(s)
      Kodama S, Toyonaga T, Kondo T, Matsumoto K, Tsuruzoe K, Kawashima J, Goto H, Kume K, Kume S, Sakakida M, Araki E
    • Journal Title

      Biochem Biophys Res Commun 327

      Pages: 1170-1178

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390266
  • [Journal Article] Enhanced expression of PDX-1 and Ngn3 by exendin-4 during beta cell regeneration in STZ-treated mice.2005

    • Author(s)
      Kodama S, Toyonaga T, Kondo T, Matsumoto K, Tsuruzoe K, Kawashima J, Goto H, Kume K, Kume S, Sakakida M, Araki E.
    • Journal Title

      Biochem Biophys Res Commun 327

      Pages: 1170-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590942
  • 1.  ARAKI Eiichi (10253733)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 1 results
  • 2.  MIYAMURA Nobuhiro (40274716)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  SAKAKIDA Michiharu (50170577)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  SHICHIRI Motoaki (00028515)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  NISHIKAWA Takeshi (70336212)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  TSURUZOE Kaku (50398202)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  SHIROTANI Tetsuya (30274715)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  MATSUMOTO Kazuya (80346999)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 9.  NISHIDA Kenro (50336244)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  KISHIKAWA Hideki (30161441)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KONDO Tatsuya (70398204)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  松村 剛 (20398192)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  笹原 誉之 (20304991)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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