OKUBO Akiko 大久保明子

… Alternative Names

大久保明子オオクボアキコ

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Researcher Number	60295251
External Links
Affiliation (based on the past Project Information) *help	2004 – 2008: Kagoshima University, University Hospital, Faculty of Medicine and Dentistry, Assistant professor, 医学部・歯学部附属病院, 講師 2003: 鹿児島大学, 医学部・歯学部附属病院, 助手 2000: 鹿児島大, 医学部附属病院, 助手 1998 – 1999: 鹿児島大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Ophthalmology / Ophthalmology
Keywords	Principal Investigator treatment / pathogenesis / polypoidal choroidal vasculopathy / 治療 / 病態 / ポリープ状脈絡膜血管症 / 加齢黄斑変性 / 脈絡膜血管 / age-related macular degeneration / choroidal vessel … More / 紫外線 / 蛋白分解酵素阻害剤 / Bruch膜 / 蛋白分解酵素阻害剤(E-64) / 網膜色素上皮 / リポフスチン / 加齢 Less

The role of sunlight exposure, humoral factors, and arteriosclerosis in age-related macular degenerationPrincipal Investigator
- Principal Investigator
  
  OKUBO Akiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kagoshima University
Pathogenesis of polypoidal choroidal vasculopathy focusing on the extracellular matrixPrincipal Investigator
- Principal Investigator
  
  OKUBO Akiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kagoshima University
Pathogenesis of polypoidal choroidal vasculopathy focusing on the peculiarity of chorotial vesselsPrincipal Investigator
- Principal Investigator
  
  OKUBO Akiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kagoshima University
加齢細膜における色素上皮の増殖Principal Investigator
- Principal Investigator
  
  大久保明子
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Ophthalmology
- Research Institution
  Kagoshima University
加齢性黄斑変性症のモデルPrincipal Investigator
- Principal Investigator
  
  大久保明子
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Ophthalmology
- Research Institution
  Kagoshima University

All 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

[Book] 眼科プラクティス21巻眼底画像所見を読み解く2008
- Author(s)
  大久保明子(田野保雄ら編)
- Publisher
  文光堂(印刷中)
- Data Source
  KAKENHI-PROJECT-19592028
[Book] 眼底画像所見を読み解く(田野保雄他編)II.加齢黄斑変性 3.ポリープ状脈絡膜血管症眼科診療プラクティス212008
- Author(s)
  大久保明子
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-19592028
[Book] 黄斑部の網膜剥離と網膜色素上皮剥離. 眼科検査のグノーティ・セアウトン
- Author(s)
  大久保明子
- Publisher
  シナジー出版(印刷中)
- Data Source
  KAKENHI-PROJECT-19592028
[Journal Article] Nasal and independent polypoidal lesions in polypoidal choroidal vasculopathy.2009
- Author(s)
  Okubo A, et al.
- Journal Title
  
  Graefe's Arch Clin Exp Ophthalmol 247(3)
  
  Pages: 421-425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592028
[Journal Article] Intraocular expression and release of high-mobility group box 1 protein in retinal detachment.2009
- Author(s)
  Arimura N, Ki-Y, Hashiguchi T, Kawahara K, Biswas KK, Nakamura M, Sonoda Y, Yamakiri K, Okubo A, Sakamoto T, Maruyama I.
- Journal Title
  
  Lab Invest 89
  
  Pages: 278-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592028
[Journal Article] Nasal and independent polypoidal lesions in polypoidal choroidal vasculopathy.2009
- Author(s)
  Okubo A, et al.
- Journal Title
  
  Graefe's Arch Clin Exp Ophthalmol 247
  
  Pages: 421-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592028
[Journal Article] Age-related maculopathy and sunlight exposure evaluated by objective measurement.2008
- Author(s)
  Hirakawa M. Tanaka M, Tanaka Y, Okubo A, Koriyama C, Tsuji M, Akiba S, Miyamoto K, Hillebrand G, Yamashita T, Sakamoto T. et al
- Journal Title
  
  Br J Ophthalmol 92
  
  Pages: 630-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592028
[Journal Article] Clinical features of early and late stage polypoidal choroidal vasculopathy characterized by lesion size and disease duration2008
- Author(s)
  Okubo A, et. al.
- Journal Title
  
  Graefes Arch Clin Exp Ophthalmol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592028
[Journal Article] Clinical features of early and late stage polypoidal choroidal vasculopathy characterized by lesion size and disease duration.2008
- Author(s)
  Okubo A, et al.
- Journal Title
  
  Graefe's Arch Clin Exp Ophthalmol 246
  
  Pages: 491-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592028
[Journal Article] 眼底画像所見を読み解く II. 加齢黄斑変性 3. ポリープ状脈絡膜血管症2008
- Author(s)
  大久保明子
- Journal Title
  
  眼科診療プラクティス 21
  
  Pages: 186-187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592028
[Journal Article] Clinical features of early and late stage polypoidal choroidal vasculopathy characterized by lesion size and disease duration.2008
- Author(s)
  Okubo A, et al.
- Journal Title
  
  Graefe's Arch Clin Exp Ophthalmol 246(4)
  
  Pages: 491-499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592028
[Journal Article] 網膜硝子体の診療の進歩 : 治療手技の進歩.加齢黄斑変性.ポリープ状脈絡膜血管症2007
- Author(s)
  大久保明子
- Journal Title
  
  あたらしい眼科 24
  
  Pages: 118-123
- Data Source
  KAKENHI-PROJECT-19592028
[Journal Article] 加齢黄斑変性の薬物治療.ステロイド2007
- Author(s)
  大久保明子
- Journal Title
  
  あたらしい眼科 24・3
  
  Pages: 291-296
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] 網膜硝子体の診療の進歩:治療手技の進歩.加齢黄斑変性.ポリープ状脈絡膜血管症2007
- Author(s)
  大久保明子
- Journal Title
  
  あたらしい眼科 24
  
  Pages: 118-123
- Data Source
  KAKENHI-PROJECT-19592028
[Journal Article] Steroid : Triamcinolone acetonide.2007
- Author(s)
  Okubo A
- Journal Title
  
  Atarashii Ganka 24 (3)
  
  Pages: 291-296
- NAID
  10022614113
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] Gene transfer to comeal epithelium and keratocytes mediated by ultrasound with microbubbles.2006
- Author(s)
  Sonoda S, Tachibana K, Uchino E, Okubo A, Yamamoto M, Sakoda K, Hisatomi T, Sonoda KH, Negishi Y, Izumi Y, Takao S, Sakamoto T
- Journal Title
  
  Invest Ophthalmol Vis Sci 47 (2)
  
  Pages: 558-64
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] Intravitreal triamcinolone acetonide for exudative age-related macular degeneration among Japanese patients2006
- Author(s)
  Ito M, Okubo A, Sonoda Y, Yamakiri K, Sakamoto T
- Journal Title
  
  Ophthalmologica 220 (2)
  
  Pages: 118-124
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] 黄斑疾患の診断と治療加齢黄斑変性(トリアムシノロン硝子体腔内注入を行った症例)2006
- Author(s)
  大久保明子
- Journal Title
  
  日本眼科紀要 57・1
  
  Pages: 68-70
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] Age-related macular degeneration (A case report treated by a intravitreal injection of triamcinolone acetonide).2006
- Author(s)
  Okubo A
- Journal Title
  
  Folia Ophthalmol 57 (1)
  
  Pages: 68-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] Light and shadow of intravitreal triamcinolone.2006
- Author(s)
  Sakamoto T, Yamakiri K, Okubo A, Doi N
- Journal Title
  
  Ganka Ophahtlmology 48 (3)
  
  Pages: 295-302
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] 黄斑疾患の診断と治療加齢黄斑変性(トリアムシノロン硝子体腔内注入を行った症例)2006
- Author(s)
  大久保明子
- Journal Title
  
  日本眼科紀要 57・1
  
  Pages: 68-70
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] ポリープ状脈絡膜血管症の病理2005
- Author(s)
  大久保明子他
- Journal Title
  
  眼科 47・1
  
  Pages: 71-77
- Data Source
  KAKENHI-PROJECT-15591866
[Journal Article] ポリープ状脈絡膜血管症の病理2005
- Author(s)
  大久保明子ら
- Journal Title
  
  眼科 47・1
  
  Pages: 71-77
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] ポリープ状脈絡膜血管症の病理2005
- Author(s)
  大久保明子ら
- Journal Title
  
  眼科 47
  
  Pages: 71-77
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] Visual improvement following trans-Tenon's retrobulbar triamcinolone acetonide infusion for polypoidal choroidal vasculopathy2005
- Author(s)
  Okubo A. et al.
- Journal Title
  
  Graefe's Arch Clin Exp Ophthalmol 243・8
  
  Pages: 837-839
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] ポリープ状脈絡膜血管症の病理2005
- Author(s)
  大久保明子他
- Journal Title
  
  眼科 47・1
  
  Pages: 71-77
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591866
[Journal Article] Pulsatile blood flow in the polypoidal choroidal vasculopathy2005
- Author(s)
  Okubo A. et al.
- Journal Title
  
  Ophthalmology 112
  
  Pages: 1436-1441
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] 「研究成果報告書概要(欧文)」より2005
- Author(s)
  Okubo A, Kanda S, Uemura A, Sameshima M, Sakamoto T
- Journal Title
  
  Ganka Ophthalmology 47 (1)
  
  Pages: 71-77
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] Pulsatile blooe flow in the polypoidal choroidal vasculopathy.2005
- Author(s)
  Okubo A, Ito M, Sameshima M, Uemura A, Sakamoto T
- Journal Title
  
  Ophthalmology 112 (8)
  
  Pages: 1436-1441
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] Visual improvement following trans-Tenon's retrobulbar triamcinolone infusion for polypoidal choroidal vasculopathy.2005
- Author(s)
  Okubo A, Ito M, Kamisasanuki, Sakamoto T
- Journal Title
  
  Graefe's Arch Clin Exp Ophthalmol 243(8)
  
  Pages: 837-839
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] Pulsatile blood flow in the polypoidal choroidal vasculopathy2005
- Author(s)
  Okubo A. et al.
- Journal Title
  
  Ophthalmology 112・8
  
  Pages: 1436-1441
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] Visual improvement following trans-Tenon's retrobulbar triamcinolone infusion for polypoidal choroidal vasculopathy2005
- Author(s)
  Okubo A. et al.
- Journal Title
  
  Graefe's Arch Clin Exp Ophthalmol 243・8
  
  Pages: 837-839
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] Reduced N-acetylasparate levels in mice lacking Aralar, a brain-and muscle-type mitochondrial aspartate-glutamate carrier.2005
- Author(s)
  Jalil MA, Begum L, Contreras L, Pardo B, Iijima M, Li MX, Ramos M, Marmol P, Horiuchi M, Shimotsu K, Nakagawa S, Okubo A, Sameshima M, Isashiki Y, Arco A, Kobayashi K, Satrustegui J, Saheki T
- Journal Title
  
  J Biol Chem 280 (35)
  
  Pages: 31333-31339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] Plasticity of polypoidal lesions in polypoidal choroidal vasculopathy2004
- Author(s)
  Okubo A, Sameshima M, Sakamoto T
- Journal Title
  
  Graefe's Archive for Clinical and Experimental Ophthalmology 242(11)
  
  Pages: 962-965
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591866
[Journal Article] Plasticity of polypoidal lesions in polypoidal choroidal vasculopathy2004
- Author(s)
  Okubo A, Sameshima M, Sakamoto T
- Journal Title
  
  Graefe's Archive for Clinical and Experimental Ophthalmology 242・11
  
  Pages: 962-965
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591866
[Journal Article] 加齢黄斑変性の薬物治療. ステロイド
- Author(s)
  大久保明子
- Journal Title
  
  あたらしい眼科 (印刷中)
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] Visual Improvement following trans-Tenon's retrobulbar triamcinolone infusion for polypoidal choroidal vasculopathy
- Author(s)
  Okubo A, Ito M, Kamisasanuki T, Sameshima M, Sakamoto T
- Journal Title
  
  Graefe's Archive for Clinical and Experimental Ophthalmology In press
- Data Source
  KAKENHI-PROJECT-15591866
[Journal Article] Visual improvement following trans-Tenon's retrobulbar triamcinolone infusion for polypoidal choroidal vasculopathy
- Author(s)
  Okubo A, Ito M, Kamisasanuki T, Sameshima M, Sakamoto T
- Journal Title
  
  Graefe's Archive for Clinical and Experimental Ophthalmology In press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591866
[Journal Article] Visual improvement following trans-Tenon's retorobulular triamcinolone Infusion for polypoidal choroidal vasculopathy
- Author(s)
  Okubo A, Ito M, Kamisasanuki T, Sameshima M, Sakamoto T
- Journal Title
  
  Graefe's Archive for Clinical and Experimental Ophthalmology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591866
[Journal Article] Pulsatile blood flow in the polypoidal choroidal vasculopathy
- Author(s)
  Okubo A, Ito M, Sameshima M, Uemura A, Sakamoto T
- Journal Title
  
  Ophthalmology In press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591866
[Journal Article] 黄斑疾患の診断と治療加齢黄斑変性(トリアムシノロン硝子体腔内注入を行った症例)
- Author(s)
  大久保明子
- Journal Title
  
  日本眼科紀要印刷中
- Data Source
  KAKENHI-PROJECT-17591844
[Journal Article] Intravitreal triamcinolone acetonide for exudative age related macular Degeneration of Japanese patients
- Author(s)
  Ito M, Okubo A, Sonoda Y et al.
- Journal Title
  
  Ophthalmologica (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591866
[Journal Article] Pulsatile blood flow in the polypoidal choroidal vasculopathy
- Author(s)
  Okubo A, Ito M, Sameshima M, Uemura A, Sakamoto T
- Journal Title
  
  Ophthalmology In press
- Data Source
  KAKENHI-PROJECT-15591866
[Journal Article] Pulsatile blood flow in the poloypoidal choroidal vasculopathy
- Author(s)
  Okubo A, Ito M, Sameshima M, Uemura A, Sakamoto T
- Journal Title
  
  Ophthalmology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591866
[Journal Article] Intravitreal triamcinolone acetonide for exudative age related macular degeneration of Japanese patients
- Author(s)
  Ito M, Okubo A, Sonoda Y et al.
- Journal Title
  
  Ophthalmologica In press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591866
[Presentation] Benign natural course of a patient with polypoidal choroidal vasculopathy observed over a five-year period.2008
- Author(s)
  Okubo A, et al.
- Organizer
  World Congress of Ophthalmology
- Place of Presentation
  香港
- Year and Date
  2008-06-28
- Data Source
  KAKENHI-PROJECT-19592028
[Presentation] Nasal and independent lesions in polypoidal choroidal vasculopathy.2008
- Author(s)
  Okubo A, et al.
- Organizer
  The first joint meeting of Korea-China-Japan Ophthalmologists.
- Place of Presentation
  Seoul
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19592028
[Presentation] ポリープ状脈絡膜血管症の長期自然経過2008
- Author(s)
  大久保明子他
- Organizer
  第47回日本網膜硝子体学会総会・第25回日本眼循環学会合同学会
- Place of Presentation
  京都
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-19592028
[Presentation] Early indications of polypoidal choroidal vasculopathy Early indications of polypoidal choroidal vasculopathy.2007
- Author(s)
  Okubo A, et al.
- Organizer
  ARVO
- Place of Presentation
  Fort Lauderdale, USA
- Year and Date
  2007-05-07
- Data Source
  KAKENHI-PROJECT-19592028
[Presentation] ポリープ状脈絡膜血管症の病理と病態 (シンポジウム)2007
- Author(s)
  大久保明子
- Organizer
  第24回日本眼循環学会
- Place of Presentation
  香川
- Year and Date
  2007-07-14
- Data Source
  KAKENHI-PROJECT-19592028
[Presentation] Early indications of polypoidal choroidal vasculopathy2007
- Author(s)
  Okubo A, et. al.
- Organizer
  The association for research in vision and ophthalmology
- Place of Presentation
  Fort Lauderdale, USA
- Year and Date
  2007-05-07
- Data Source
  KAKENHI-PROJECT-19592028
[Presentation] 初期のポリープ状脈絡膜血管症の特徴2007
- Author(s)
  大久保明子他
- Organizer
  第111回日本眼科学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-04-19
- Data Source
  KAKENHI-PROJECT-19592028
[Presentation] シンポジウム:ポリープ状脈絡膜血管症の病理と病態2007
- Author(s)
  大久保明子
- Organizer
  第24回日本眼循環学会
- Place of Presentation
  香川
- Year and Date
  2007-07-14
- Data Source
  KAKENHI-PROJECT-19592028

1. SAKAMOTO Taiji (10235179)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results

OKUBO Akiko 大久保 明子

大久保 明子 オオクボ アキコ

Research Projects

Research Products

Co-Researchers

The role of sunlight exposure, humoral factors, and arteriosclerosis in age-related macular degenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathogenesis of polypoidal choroidal vasculopathy focusing on the extracellular matrixPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathogenesis of polypoidal choroidal vasculopathy focusing on the peculiarity of chorotial vesselsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

加齢細膜における色素上皮の増殖Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

加齢性黄斑変性症のモデルPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 眼科プラクティス21巻 眼底画像所見を読み解く2008

Author(s)

Publisher

Data Source

[Book] 眼底画像所見を読み解く(田野保雄他編)II.加齢黄斑変性 3.ポリープ状脈絡膜血管症眼科診療プラクティス212008

Author(s)

Publisher

Data Source

[Book] 黄斑部の網膜剥離と網膜色素上皮剥離. 眼科検査のグノーティ・セアウトン

Author(s)

Publisher

Data Source

[Journal Article] Nasal and independent polypoidal lesions in polypoidal choroidal vasculopathy.2009

Author(s)

Journal Title

Data Source

[Journal Article] Intraocular expression and release of high-mobility group box 1 protein in retinal detachment.2009

Author(s)

Journal Title

Data Source

[Journal Article] Nasal and independent polypoidal lesions in polypoidal choroidal vasculopathy.2009

Author(s)

Journal Title

Data Source

[Journal Article] Age-related maculopathy and sunlight exposure evaluated by objective measurement.2008

Author(s)

Journal Title

Data Source

[Journal Article] Clinical features of early and late stage polypoidal choroidal vasculopathy characterized by lesion size and disease duration2008

Author(s)

Journal Title

Data Source

[Journal Article] Clinical features of early and late stage polypoidal choroidal vasculopathy characterized by lesion size and disease duration.2008

Author(s)

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[Journal Article] 眼底画像所見を読み解く II. 加齢黄斑変性 3. ポリープ状脈絡膜血管症2008

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[Journal Article] Clinical features of early and late stage polypoidal choroidal vasculopathy characterized by lesion size and disease duration.2008

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[Journal Article] 網膜硝子体の診療の進歩 : 治療手技の進歩.加齢黄斑変性.ポリープ状脈絡膜血管症2007

OKUBO Akiko 大久保明子

大久保明子オオクボアキコ

[Book] 眼科プラクティス21巻眼底画像所見を読み解く2008

[Journal Article] 黄斑疾患の診断と治療加齢黄斑変性(トリアムシノロン硝子体腔内注入を行った症例)2006