SHIMIZU-IBUKA Akiko 井深章子

… Alternative Names

SHIMIZU Akiko 清水章子

井深章子イブカアキコ

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Researcher Number	60301420
Other IDs
Affiliation (Current)	2025: 神奈川大学, 化学生命学部, 教授
Affiliation (based on the past Project Information) *help	2025: 神奈川大学, 化学生命学部, 教授 2016 – 2021: 新潟薬科大学, 応用生命科学部, 教授 2014 – 2016: 新潟薬科大学, 応用生物科学部, 教授 2012 – 2013: 山形大学, 理学部, 准教授 2007 – 2008: Tokyo University of Agriculture, 応用生物科学部, 講師
Review Section/Research Field	Principal Investigator Food science / Basic Section 38030:Applied biochemistry-related / Basic Section 49050:Bacteriology-related Except Principal Investigator Eating habits
Keywords	Principal Investigator 阻害剤 / tRNase / 感染症 / 薬剤耐性菌 / tRNase Z / ホモセリンラクトナーゼ / β-ラクタマーゼ / MBLスーパーファミリー / ミラクリン / 味覚修飾活性 … More / 甘味タンパク質 / 甘味受容体 / 構造 / タンパク質 / 甘味 / 食品機能学 … More Except Principal Investigator 食と健康 / SKn-1マウス / 脳腸軸 / 食と栄養 / 食品機能 / エネルギー代謝 / 味物質科学 / 刷子細胞 / Skn-1マウス / 味覚シグナル Less

アラニンラセマーゼの触媒機能：有機酸・D型基質による活性制御と副反応の解析Principal Investigator
- Principal Investigator
  
  井深章子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Kanagawa University
Analysis of unknown activity of metallo-beta-lactamase and search for novel inhibitorsPrincipal Investigator
- Principal Investigator
  
  Ibuka Akiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Nigata University of Phermacy and Applied Life Sciences
Analysis of taste-modifying mechanism of miraculin using miraculin-like proteinsPrincipal Investigator
- Principal Investigator
  
  SHIMIZU-IBUKA Akiko
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Nigata University of Phermacy and Applied Life Sciences
Peripheral Response to Tastant Signals and Central Cognition for Analysis of Their Coordination and its Application to the Science of Food for Life
- Principal Investigator
  
  Abe Keiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Eating habits
- Research Institution
  The University of Tokyo
Analysis of taste-recognition mechanism through taste receptorPrincipal Investigator
- Principal Investigator
  
  SHIMIZU-IBUKA Akiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Nigata University of Phermacy and Applied Life Sciences
  Yamagata University
Structure-function analysis of sweetness-related proteinsPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Akiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  Tokyo University of Agriculture

All 2021 2020 2018 2017 2015 2008 2007 Other

All Journal Article Presentation Book

[Book] Sweetness and Sweeteners-Biology, Chemistry, and Psychophysics2008
- Author(s)
  Shimizu-Ibuka, A, Morita, Y., Naakajima, K., Asakura, T., Terada, T., Misaka, T., and Abe, K
- Publisher
  Oxford University Press
- Data Source
  KAKENHI-PROJECT-19780103
[Book] Sweetness and Sweeteners-Biology, Chemistry, and Psychophysics2008
- Author(s)
  Shimizu-Ibuka, A.
- Total Pages
  634
- Publisher
  Oxford University Press
- Data Source
  KAKENHI-PROJECT-19780103
[Journal Article] Insights Into the Inhibition of MOX-1 β-Lactamase by S02030, a Boronic Acid Transition State Inhibitor2021
- Author(s)
  Ishikawa Tatsuya、Furukawa Nayuta、Caselli Emilia、Prati Fabio、Taracila Magdalena A.、Bethel Christopher R.、Ishii Yoshikazu、Shimizu-Ibuka Akiko、Bonomo Robert A.
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 12 Pages: 1-7
- DOI
  10.3389/fmicb.2021.720036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07566
[Journal Article] RNA-hydrolyzing activity of metallo-β-lactamase IMP-12020
- Author(s)
  Yoshiki Kato, Masayuki Takahashi, Mineaki Seki, Masayuki Nashimoto, Akiko Shimizu-Ibuka
- Journal Title
  
  PLoS One
  
  Volume: 15 Issue: 10 Pages: e0241557-e0241557
- DOI
  10.1371/journal.pone.0241557
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07566
[Journal Article] Structural and functional analysis of miraculin-like protein from Vitis vinifera2018
- Author(s)
  Ohkura So-ichiro、Hori Misaho、Saitoh Kazuki、Okuzawa Takumi、Okamoto Ikuko、Furukawa Nayuta、Shimizu-Ibuka Akiko
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  
  Volume: 1866 Issue: 11 Pages: 1125-1130
- DOI
  10.1016/j.bbapap.2018.08.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07445
[Journal Article] Long-Chain Fatty Acids Elicit a Bitterness-Masking Effect on Quinine and Other Nitrogenous Bitter Substances by Formation of Insoluble Binary Complexes.2015
- Author(s)
  Ogi, K., Yamashita, H., Terada, T., Homma, R., Shimizu-Ibuka, A., Yoshimura, E., Ishimaru, Y., Abe, K., and Asakura, T.
- Journal Title
  
  J. Agric. Food Chem.
  
  Volume: 63 Issue: 38 Pages: 8493-8500
- DOI
  10.1021/acs.jafc.5b03193
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K12334, KAKENHI-PROJECT-26242007, KAKENHI-PROJECT-26660108, KAKENHI-PROJECT-25292068
[Journal Article] Identification of key neoculin residues responsible for the binding and activation of the sweet taste receptor.2015
- Author(s)
  Koizumi, T., Terada, T., Nakajima, K., Kojima, M., Koshiba, S., Matsumura, Y., Kaneda, K., Asakura, T., Shimizu, A., Abe, K., and Misaka, T.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 12947-12947
- DOI
  10.1038/srep12947
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12334, KAKENHI-PROJECT-26242007, KAKENHI-PROJECT-15H05624
[Journal Article] Biochemical and genomic analysis of neoculin compared to monocot mannose-binding lectins2008
- Author(s)
  Shimizu-Ibuka, A., Nakai, Y., Nakamori, K., Morita, Y., Nakajima, K., Kadota, K., Watanabe, H., Okubo, S., Terada, T., Asakura, T., Misaka, T., and Abe, K
- Journal Title
  
  J.Agric. Food Chem 56
  
  Pages: 5338-5344
- Data Source
  KAKENHI-PROJECT-19780103
[Journal Article] Acid-induced sweetness of neoculin is ascribed to its pH-dependent agonistic-antagonistic interaction with human sweet taste receptor2008
- Author(s)
  Nakajima, K., Morita, Y., Koizumi, A., Asakura, T., Terada, T., Ito, K., Shimizu-Ibuka, A., Maruyama, J., Kitamoto, K., Misaka, T., and Abe, K
- Journal Title
  
  FASEB J 22
  
  Pages: 2323-2330
- Data Source
  KAKENHI-PROJECT-19780103
[Journal Article] Biochemical and genomic analysis of neoculin compared to monocot man nose-binding lectins2008
- Author(s)
  Shimizu-Ibuka, A.
- Journal Title
  
  J. Agric. Food Chem 56
  
  Pages: 5338-5344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19780103
[Journal Article] Taste-modifying sweet protein,neoculin, is received at human T1R3 amino terminal domain2007
- Author(s)
  Koizumi, A., Nakajima, K., Asakura, T., Morita, Y., Ito, K., Shimizu-Ibuka, A., Misaka, T., and Abe, K
- Journal Title
  
  Biochem.Biophys. Res. Commun 358
  
  Pages: 585-589
- Data Source
  KAKENHI-PROJECT-19780103
[Presentation] メタロβ-ラクタマーゼIMP-1のRNA加水分解活性2020
- Author(s)
  加藤善輝、高橋昌幸、関峰秋、梨本正之、井深章子
- Organizer
  日本生化学会2020年度大会
- Data Source
  KAKENHI-PROJECT-19K07566
[Presentation] ブドウ由来ミラクリン類似タンパク質の構造解析2017
- Author(s)
  大倉宗一郎、堀実佐穂、古川那由太、○井深章子
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学
- Year and Date
  2017-03-18
- Data Source
  KAKENHI-PROJECT-15K07445
[Presentation] 粉末あるいは固形飼料を摂取させたラットの摂食行動および視床における発現遺伝子の比較解析2015
- Author(s)
  永井俊匡、清水愛恵、齊藤美佳、緑川景子、熊倉慧、阿部啓子、朝倉富子
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山
- Year and Date
  2015-03-27
- Data Source
  KAKENHI-PROJECT-26242007
[Presentation] ヒト甘味受容体タンパク質 hT1R2/hT1R3ATD の発現・精製
- Author(s)
  佐藤沙知、大石佳奈、大谷典正、井深章子
- Organizer
  日本農芸化学会東北支部第147回大会
- Place of Presentation
  弘前大学
- Data Source
  KAKENHI-PROJECT-24580172

1. Abe Keiko (10151094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. ASAKURA Tomiko (20259013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. MISAKA Takumi (40373196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ISHIMARU Yoshiro (10451840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 梨本正之 (30228069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

SHIMIZU-IBUKA Akiko 井深 章子

SHIMIZU Akiko 清水 章子

井深 章子 イブカ アキコ

Research Projects

Research Products

Co-Researchers

アラニンラセマーゼの触媒機能：有機酸・D型基質による活性制御と副反応の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of unknown activity of metallo-beta-lactamase and search for novel inhibitorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of taste-modifying mechanism of miraculin using miraculin-like proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Peripheral Response to Tastant Signals and Central Cognition for Analysis of Their Coordination and its Application to the Science of Food for Life

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of taste-recognition mechanism through taste receptorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structure-function analysis of sweetness-related proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Sweetness and Sweeteners-Biology, Chemistry, and Psychophysics2008

Author(s)

Publisher

Data Source

[Book] Sweetness and Sweeteners-Biology, Chemistry, and Psychophysics2008

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Insights Into the Inhibition of MOX-1 β-Lactamase by S02030, a Boronic Acid Transition State Inhibitor2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RNA-hydrolyzing activity of metallo-β-lactamase IMP-12020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural and functional analysis of miraculin-like protein from Vitis vinifera2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long-Chain Fatty Acids Elicit a Bitterness-Masking Effect on Quinine and Other Nitrogenous Bitter Substances by Formation of Insoluble Binary Complexes.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of key neoculin residues responsible for the binding and activation of the sweet taste receptor.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Biochemical and genomic analysis of neoculin compared to monocot mannose-binding lectins2008

Author(s)

Journal Title

Data Source

SHIMIZU-IBUKA Akiko 井深章子

SHIMIZU Akiko 清水章子

井深章子イブカアキコ