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IZUMI TAKESHI  泉 剛

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IZUMI Takeshi  泉 剛

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Researcher Number 60312360
Other IDs
External Links
Affiliation (Current) 2025: 北海道医療大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2017 – 2024: 北海道医療大学, 薬学部, 教授
2018: 北海道大学, 医学研究科, 准教授
2017: 北海道大学, 大学院医学研究科, 講師
2016: 北海道大学, 医学研究科, 准教授
2015: 北海道大学, 医学(系)研究科(研究院), 准教授 … More
2012 – 2014: 北海道大学, 医学(系)研究科(研究院), 講師
2013: 北海道大学, 医学研究科, 講師
2011: 北海道大学, 大学院・医学研究科, 講師
2007 – 2011: Hokkaido University, 大学院・医学研究科, 助教
2008: 北海道大学, 医学部, 助教 Less
Review Section/Research Field
Principal Investigator
Psychiatric science / Basic Section 52030:Psychiatry-related
Except Principal Investigator
Psychiatric science / Basic Section 10040:Experimental psychology-related / Basic Section 52030:Psychiatry-related
Keywords
Principal Investigator
海馬 / 動物モデル / うつ病 / 扁桃体 / 不安 / 精神薬理学 / ストレス / HPA axis / FKBP5 / SSRI … More / テロメア―ゼ / 幼若期ストレス / β-catenin / テロメラーゼ / テロメア / 副腎皮質ホルモン / 視床下部-下垂体-副腎系 / 抗うつ薬 / 拘束ストレス / mTOR / Akt / 脳・神経 / 室傍核 / 副腎 / HPA系 / グルココルチコイド / うつ病モデル動物 / 5-HT … More
Except Principal Investigator
海馬 / ストレス / miRNA / DNAメチル化 / テロメア / 神経科学 / うつ病 / 動物モデル / 自殺 / セロトニン / 精神薬理学 / 幼若期ストレス / 恐怖記憶 / 精神疾病モデル動物 / 自閉スペクトラム障害 / 刷り込み / 神経回路発達 / 認知発達 / オレキシン / テロメラーゼ / オレキシン受容体 / 母子分離ストレス / DNMT / 成体海馬神経細胞新生 / 幼少期ストレス / テロメア短縮 / バイオマーカー / ミトコンドリア / Grik4 / 消去 / 5-HT2C / DREADD / PTSD / 人工受容体 / SNP / 神経前駆細胞 / ゲノムワイド関連研究 / 自殺の生物学 / 神経幹細胞 / GWAS / RT-PCR / 内側前頭前野 / 発達 / 情動 / 縫線核 / GABA / メタ可塑性 / 脳機能発達 / 臨界期 / 脳発達 Less
  • Research Projects

    (15 results)
  • Research Products

    (121 results)
  • Co-Researchers

    (24 People)
  •  Epigenesis of predisposed imprinting and autism-like disorder

    • Principal Investigator
      松島 俊也
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 10040:Experimental psychology-related
    • Research Institution
      Hokkaido University
  •  うつ病における脳内テロメア短縮のメカニズムー動物モデルによる検討Principal Investigator

    • Principal Investigator
      泉 剛
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  Mechanisms of miRNA regulation of hippocampal telomere length shortening in depression

    • Principal Investigator
      Shikanai Hiroki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  The role of the amygdala in depressionPrincipal Investigator

    • Principal Investigator
      IZUMI Takeshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  Stress, depression, and suicide - molecular basis of the downward spiral

    • Principal Investigator
      Hishimoto Akitoyo
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Psychiatric science
    • Research Institution
      Yokohama City University
      Kobe University
  •  Elucidation of neural mechanisms underlying fear memory using DREADD

    • Principal Investigator
      Yoshioka Mitsuhiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Psychiatric science
    • Research Institution
      Hokkaido University
  •  The role of the hippocampus and amygdala in depressionPrincipal Investigator

    • Principal Investigator
      IZUMI TAKESHI
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Health Sciences University of Hokkaido
      Hokkaido University
  •  Epigenetic effects of early life stress on adult hippocampal neurogenesis

    • Principal Investigator
      Boku Shuken
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Kobe University
  •  Functional analysis of suicide-related genes in brain

    • Principal Investigator
      Hishimoto Akitoyo
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Kobe University
  •  SSRI exerts anxiolytic effect via amygdalar 5-HTergic neural systemPrincipal Investigator

    • Principal Investigator
      IZUMI TAKESHI
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Hokkaido University
  •  Functional develpment of 5-HT/GABA neurons in the raphe nuclei - postnatal stress and epigenetics

    • Principal Investigator
      YOSHIOKA Mitsuhiro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Psychiatric science
    • Research Institution
      Hokkaido University
  •  Neural mechanism of anxiety and fearPrincipal Investigator

    • Principal Investigator
      IZUMI Takeshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Hokkaido University
  •  Effects of early postnatal stress on the development of 5-HT/GABA co-localized neuron in the raphe nuclei

    • Principal Investigator
      YOSHIOKA Mitsuhiro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Psychiatric science
    • Research Institution
      Hokkaido University
  •  Study about the amygdala and anxiety-related neural circuit in brainPrincipal Investigator

    • Principal Investigator
      IZUMI Takeshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Hokkaido University
  •  A study of neural circuits underlying stress regulation at the critical period during brain development

    • Principal Investigator
      MATSUMOTO Machiko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      Health Sciences University of Hokkaido

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

  • [Book] Facilitating resilience after trauma.2018

    • Author(s)
      Pinna G and Izumi T, editor
    • Total Pages
      255
    • Publisher
      Nova Science Publishers
    • ISBN
      9781536130973
    • Data Source
      KAKENHI-PROJECT-16K10183
  • [Book] Role of the amygdalarserotonergic system in emotional regulation and disorders, In:Insights into the Amygdala, chapter 22012

    • Author(s)
      Izumi T , Yoshida T, Watanabe M, Yoshioka M
    • Publisher
      Nova Science Publishers, Inc
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Journal Article] Impaired monoamine neural system in the mPFC of SHRSP/Ezo as an animal model of attention-deficit/hyperactivity disorder2024

    • Author(s)
      Suzuki Naoya、Hiraide Sachiko、Shikanai Hiroki、Isshiki Takeru、Yamaguchi Taku、Izumi Takeshi、Iizuka Kenji
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 154 Issue: 2 Pages: 61-71

    • DOI

      10.1016/j.jphs.2023.12.002

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07133, KAKENHI-PROJECT-21K07506
  • [Journal Article] 5-HT Neural System Abnormalities in PTSD Model Rats2023

    • Author(s)
      Shikanai Hiroki、Matsuzaki Hirokazu、Kasai Rina、Kusaka Shota、Shindo Tsugumi、Izumi Takeshi
    • Journal Title

      Neuromethods

      Volume: 198 Pages: 203-213

    • DOI

      10.1007/978-1-0716-3218-5_10

    • ISBN
      9781071632178, 9781071632185
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Journal Article] 5-HT neural system abnormalities in PTSD model rats.2023

    • Author(s)
      Shikanai Hiroki, Matsuzaki Hirokazu, Kasai Rina, Kusaka Shota, Shindo Tsugumi, Izumi Takeshi
    • Journal Title

      NeuroMethods

      Volume: 198 Pages: 203-213

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07622
  • [Journal Article] D-serine metabolism in the medial prefrontal cortex, but not the hippocampus, is involved in AD/HD-like behaviors in SHRSP/Ezo2022

    • Author(s)
      Shindo Tsugumi、Shikanai Hiroki、Watarai Akane、Hiraide Sachiko、Iizuka Kenji、Izumi Takeshi
    • Journal Title

      European Journal of Pharmacology

      Volume: 923 Pages: 174930-174930

    • DOI

      10.1016/j.ejphar.2022.174930

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08079, KAKENHI-PROJECT-21K07506, KAKENHI-PROJECT-22K07622
  • [Journal Article] Separation and detection of D-/L-serine by conventional HPLC2022

    • Author(s)
      Shikanai Hiroki、Ikimura Kazuko、Miura Momoko、Shindo Tsugumi、Watarai Akane、Izumi Takeshi
    • Journal Title

      MethodsX

      Volume: 9 Pages: 101752-101752

    • DOI

      10.1016/j.mex.2022.101752

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07506, KAKENHI-PROJECT-22K07622
  • [Journal Article] Tbx1, a gene encoded in 22q11.2 copy number variant, is a link between alterations in fimbria myelination and cognitive speed in mice2021

    • Author(s)
      Hiramoto Takeshi、Sumiyoshi Akira、Yamauchi Takahira、Tanigaki Kenji、Shi Qian、Kang Gina、Ryoke Rie、Nonaka Hiroi、Enomoto Shingo、Izumi Takeshi、Bhat Manzoor A.、Kawashima Ryuta、Hiroi Noboru
    • Journal Title

      Molecular Psychiatry

      Volume: 未定 Issue: 2 Pages: 929-938

    • DOI

      10.1038/s41380-021-01318-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08079, KAKENHI-PROJECT-20K07319
  • [Journal Article] Genome-wide association studies identify polygenic effects for completed suicide in the Japanese population.2019

    • Author(s)
      Otsuka I, Akiyama M, Shirakawa O, Okazaki S, Momozawa Y, Kamatani Y, Izumi T, Numata S, Takahashi M, Boku S, Sora I, Yamamoto K, Ueno Y, Toda T, Kubo M, Hishimoto A
    • Journal Title

      Neuropsychopharmacology

      Volume: 44 Issue: 12 Pages: 2119-2124

    • DOI

      10.1038/s41386-019-0506-5

    • NAID

      120007027666

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08079, KAKENHI-PROJECT-18K15483, KAKENHI-PROJECT-17H04249
  • [Journal Article] Computational analysis of neonatal mouse ultrasonic vocalization.2018

    • Author(s)
      Ó Broin P, Beckert MV, Takahashi T, Izumi T, Ye K, Kang G, Pouso P, Topolski M, Pena JL, Hiroi N
    • Journal Title

      Curr Protoc Mouse Biol

      Volume: 8(2) Issue: 2

    • DOI

      10.1002/cpmo.46

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10183
  • [Journal Article] Repeated fluvoxamine treatment recovers early postnatal stress-induced hypersociability-like behavior in adult rats.2018

    • Author(s)
      Kumamoto H, Yamaguchi T, Konno K, Izumi T, Yoshida T, Ohmura Y, Watanabe M, Yoshioka M
    • Journal Title

      Journal Pharmacological Science

      Volume: 136 Issue: 1 Pages: 1-8

    • DOI

      10.1016/j.jphs.2017.12.002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10183, KAKENHI-PROJECT-16K18974
  • [Journal Article] Copy number elevation of 22q11.2 genes arrests the developmental maturation of working memory capacity and adult hippocampal neurogenesis.2018

    • Author(s)
      Boku S, Izumi T, Abe S, Takahashi T, Nishi A, Nomaru H, Naka Y, Kang G, Nagashima M, Hishimoto A, Enomoto S, Duran-Torres G, Tanigaki K, Zhang J, Ye K, Kato S, Männistö PT, Kobayashi K, Hiroi N.
    • Journal Title

      Mol Psychiatry.

      Volume: 23 Issue: 4 Pages: 985-992

    • DOI

      10.1038/mp.2017.158

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293074, KAKENHI-PROJECT-16K10183
  • [Journal Article] Loss of chromosome Y in blood, but not in brain, of suicide completers2018

    • Author(s)
      Kimura A, Hishimoto A, Otsuka I, Okazaki S, Boku S, Horai T, Izumi T, Takahashi M, Ueno Y, Shirakawa O, Sora I
    • Journal Title

      PLoS One

      Volume: 13 Issue: 1 Pages: e0190667-e0190667

    • DOI

      10.1371/journal.pone.0190667

    • NAID

      120006382347

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04249, KAKENHI-PROJECT-15K19727, KAKENHI-PROJECT-16K10183, KAKENHI-PROJECT-16K19765, KAKENHI-PROJECT-16H06276
  • [Journal Article] N-methyl-d-aspartate receptor dysfunction in the prefrontal cortex of stroke-prone spontaneously hypertensive rat/Ezo as a rat model of attention deficit/ hyperactivity disorder.2018

    • Author(s)
      Shikanai H, Oshima N, Kawashima H, Kimura S, Hiraide S, Togashi H, Iizuka K, Ohkura K, Izumi T
    • Journal Title

      Neuropsychopharmacology Reports

      Volume: 38(2) Issue: 2 Pages: 61-66

    • DOI

      10.1002/npr2.12007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10183
  • [Journal Article] Aberrant telomere length and mitochondrial DNA copy number in suicide completers2017

    • Author(s)
      Ikuo Otsuka, Takeshi Izumi, Shuken Boku, Atsushi Kimura, Yuan Zhang, Kentaro Mouri, Satoshi Okazaki, Kyoichi Shiroiwa, Motonori Takahashi, Yasuhiro Ueno, Osamu Shirakawa, Ichiro Sora, Akitoyo Hishimoto
    • Journal Title

      Scientific Reports

      Volume: in press

    • NAID

      120006373780

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461718
  • [Journal Article] Aberrant telomere length and mitochondrial DNA copy number in suicide completers.2017

    • Author(s)
      Otsuka I, Izumi T, Boku S, Kimura A, Zhang Y, Mouri K, Okazaki S, Shiroiwa K, Takahashi M, Ueno Y, Shirakawa O, Sora I, Hishimoto A
    • Journal Title

      Scientific Report

      Volume: 7 Issue: 1 Pages: 3176-3176

    • DOI

      10.1038/s41598-017-03599-8

    • NAID

      120006373780

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10183, KAKENHI-PROJECT-16K19766, KAKENHI-PROJECT-15K19727
  • [Journal Article] Neuronal codes for the inhibitory control of impulsive actions in the rat infralimbic cortex2016

    • Author(s)
      Tsutsui-Kimura I., Ohmura Y., Izumi T., Matsushima T., Amita H., Yamaguchi T., Yoshida T, Yoshioka M.
    • Journal Title

      Behavioural Brain Research

      Volume: 296 Pages: 361-372

    • DOI

      10.1016/j.bbr.2015.08.025

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460637, KAKENHI-PROJECT-26650114, KAKENHI-PUBLICLY-26118701, KAKENHI-PUBLICLY-26120701, KAKENHI-PROJECT-14J40100, KAKENHI-PROJECT-26670534, KAKENHI-PROJECT-25291071, KAKENHI-PROJECT-25713043, KAKENHI-PROJECT-16K10183
  • [Journal Article] Structure and function of neonatal social communication in a genetic mouse model of autism.2016

    • Author(s)
      T. Takahashi, S. Okabe, P. Ó Broin, A. Nishi, K. Ye, M. V. Beckert, T. Izumi, A. Machida, G. Kang, Seiji Abe, J. L. Pena, A. Golden, T. Kikusui, N. Hiroi.
    • Journal Title

      Molecular Psychiatry

      Volume: in press Issue: 9 Pages: 1-7

    • DOI

      10.1038/mp.2015.190

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14881, KAKENHI-PROJECT-15K18978, KAKENHI-PLANNED-25118007, KAKENHI-PROJECT-15H02479, KAKENHI-PROJECT-16K10183
  • [Journal Article] Mirtazapine exerts an anxiolytic-like effect through activation of the median raphe nucleus-dorsal hippocampal 5-HT pathway in contextual fear conditioning in rats.2016

    • Author(s)
      An Y, Chen C, Inoue T, Nakagawa S, Kitaichi Y, Wang C, Izumi T, Kusumi I
    • Journal Title

      Prog Neuropsychopharmacol Biol Psychiatry

      Volume: 70 Pages: 17-23

    • DOI

      10.1016/j.pnpbp.2016.04.014

    • NAID

      120006347178

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10183
  • [Journal Article] Milnacipran remediates impulsive deficits in rats with lesions of the ventromedial prefrontal cortex2014

    • Author(s)
      Tsutsui-Kimura I, Yoshida T, Ohmura Y, Izumi T, Yoshioka M
    • Journal Title

      The international journal of neuropsychopharmacology

      Volume: 8 Issue: 5 Pages: 1-14

    • DOI

      10.1093/ijnp/pyu083

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J40100, KAKENHI-PLANNED-23118003, KAKENHI-PROJECT-24591674, KAKENHI-PROJECT-25713043, KAKENHI-PUBLICLY-26118701, KAKENHI-PUBLICLY-26120701
  • [Journal Article] Tandospirone Suppresses Impulsive Action by Possible Blockade of the 5-HT<sub>1A</sub> Receptor2013

    • Author(s)
      Ohmura Y, Kumamoto H, Tsutsui-Kimura I, Minami M, Izumi T, Yoshida T, Yoshioka M.
    • Journal Title

      J Pharmacol Sci

      Volume: 122 Issue: 2 Pages: 84-92

    • DOI

      10.1254/jphs.12264FP

    • NAID

      10031185400

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04134, KAKENHI-PROJECT-23390284, KAKENHI-PROJECT-24591674, KAKENHI-PROJECT-24791192
  • [Journal Article] Milnacipran enhances the control of impulsive action by activating D_1-like receptors in the infralimbic cortex.2013

    • Author(s)
      Tsutsui-Kimura I, Ohmura Y, Izumi T, Kumamoto H, Yamaguchi
    • Journal Title

      Psychopharmacology (Berl)

      Volume: 225 Issue: 2 Pages: 495-504

    • DOI

      10.1007/s00213-012-2835-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04134, KAKENHI-PROJECT-23390284, KAKENHI-PROJECT-23790593, KAKENHI-PROJECT-23791305, KAKENHI-PROJECT-24591674, KAKENHI-PROJECT-24791192
  • [Journal Article] Lithium, but not valproic acid or carbamazepine, suppresses impulsive-like action in rats.2012

    • Author(s)
      Ohmura Y, Tsutsui-Kimura I, Kumamoto H, Minami M, Izumi T.
    • Journal Title

      Psychopharmacology (Berl)

      Volume: 219 Issue: 2 Pages: 148-153

    • DOI

      10.1007/s00213-011-2496-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04134, KAKENHI-PROJECT-21790515, KAKENHI-PROJECT-23390284, KAKENHI-PROJECT-23790593, KAKENHI-PROJECT-23791305, KAKENHI-PROJECT-24591674
  • [Journal Article] Distinct neurochemical and functional properties of GAD67-containing 5-HT neurons in the rat dorsal raphe nucleus.2012

    • Author(s)
      Shikanai H, Yoshida T, Konno K, Yamasaki M, Izumi T, Ohmura Y, Watanabe M, Yoshioka M.
    • Journal Title

      Journal of Neuroscience

      Volume: 32 Issue: 41 Pages: 14415-14426

    • DOI

      10.1523/jneurosci.5929-11.2012

    • NAID

      120005228624

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390284, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-24790187, KAKENHI-PROJECT-24791192
  • [Journal Article] Behavioral and pharmacological effects of fluvoxamine on decision-making in food patches and the inter-temporal choices of domestic chicks2012

    • Author(s)
      Shohei Matsunami, Yukiko Ogura, Hidetoshi Amita, Takeshi Izumu, Mitsushiro Yoshioka and Toshiya Matsushima
    • Journal Title

      Behavioral Brain Research

      Volume: 233 Issue: 2 Pages: 577-586

    • DOI

      10.1016/j.bbr.2012.05.045

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J02260, KAKENHI-PROJECT-12J06407, KAKENHI-PROJECT-22570070, KAKENHI-PROJECT-23390284, KAKENHI-PROJECT-24591674
  • [Journal Article] Anxiolytic effects of yokukansan, a traditional Japanese medicine, via serotonin 5-HT(1A) receptors on anxiety-related behaviors in rats experienced aversive stress2012

    • Author(s)
      Yamaguchi T, Tsujimatsu A, Kumamoto H, Izumi T, Ohmura Y, Y oshida T, Y oshioka M
    • Journal Title

      J Ethnopharmacol

      Volume: 43 Issue: 2 Pages: 533-539

    • DOI

      10.1016/j.jep.2012.07.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390284, KAKENHI-PROJECT-23790593, KAKENHI-PROJECT-24591674, KAKENHI-PROJECT-24791192
  • [Journal Article] Effects of serotonergic terminal lesion in the amygdala on conditioned fear and innate fear in rats2012

    • Author(s)
      Izumi T, Ohmura Y, Futami Y, Matsuzaki H, Kubo Y, Y oshida T, Y oshioka M
    • Journal Title

      Eur J Pharmacol

      Volume: 696 Issue: 1-3 Pages: 89-95

    • DOI

      10.1016/j.ejphar.2012.09.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390284, KAKENHI-PROJECT-24791192
  • [Journal Article] Distinct neurochemical and functional properties of GAD67-containing 5-HT neurons in the rat dorsal raphe nucleus2012

    • Author(s)
      Shikanai H, Y oshida T, Konno K, Y amasaki M, Izumi T, Ohmura Y, Watanabe M, Y oshioka M
    • Journal Title

      J Neurosci

      Volume: 32 Pages: 14415-14426

    • NAID

      120005228624

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Journal Article] Retrieval of Conditioned Fear Activates the Basolateral and Intercalated Nucleus of Amygdala2011

    • Author(s)
      Izumi, T.; Boku, S.; Shinmin, W., et al
    • Journal Title

      Journal of Neuroscience Research

      Volume: 89(5) Issue: 5 Pages: 773-790

    • DOI

      10.1002/jnr.22592

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19100005, KAKENHI-PROJECT-21591477, KAKENHI-PROJECT-21790515, KAKENHI-PROJECT-22791101, KAKENHI-PROJECT-23790593
  • [Journal Article] Retrieval of conditioned fear activates the basolateral and intercalated nucleus of amygdala2011

    • Author(s)
      Izumi T, Boku S, Shinmin W, Inoue T, Konno K, Yamaguchi T, Yoshida T, Matsumoto M, Watanabe M, Koyama T, Yoshioka M
    • Journal Title

      J Neurosci Res

      Volume: 89(5) Pages: 773-790

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591477
  • [Journal Article] Juvenile stress attenuates the dorsal hippocampus postsynaptic 5-HT1A receptor function in adult rats2011

    • Author(s)
      Matsuzaki H, Izumi T, Horinouchi T, Boku S, Inoue T, Yamaguchi T, Yoshida T, Matsumoto M, Togashi H, Miwa S, Koyama T, Yoshioka M
    • Journal Title

      Psychopharmacology

      Volume: 214(1) Pages: 329-337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591477
  • [Journal Article] Endogenous acetylcholine modulates impulsive action via alpha4beta2 nicotinic acetylcholine receptors in rats2010

    • Author(s)
      Tsutsui-Kimura I, Ohmura Y, Izumi T, Yamaguchi T, Yoshida T, Yoshioka M.
    • Journal Title

      Eur J Pharmacol

      Volume: 641(2-3) Pages: 148-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Journal Article] The serotonergic projection from the median raphe nucleus to the ventral hippocampus is involved in the retrieval of fear memory through the corticotropin-releasing factor type 2 receptor2010

    • Author(s)
      Ohmura Y, Izumi T, Yamaguchi T, Tsutsui-Kimura I, Yoshida T, Yoshioka M.
    • Journal Title

      Neuropsychopharmacology

      Volume: 35(6) Pages: 1271-8

    • NAID

      120002548777

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Journal Article] The serotonergic projection from the median raphe nucleus to the ventral hippocampus is involved in the retrieval of fear memory throughthe corticotropin-releasing factor type 2 receptor2010

    • Author(s)
      Ohmura Y, Izumi T, Yamaguchi T, Tsutsui-Kimura I, Yoshida T, Yoshioka M
    • Journal Title

      Neuropsychopharmacology

      Volume: 35 Pages: 1271-278

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Journal Article] Nicotine provokes impulsive-like action by stimulating alpha4beta2 nicotinic acetylcholine receptors2010

    • Author(s)
      Tsutsui-Kimura I, Ohmura Y, Izumi T, Yamaguchi T
    • Journal Title

      Psychopharmacoloey (Ber1)

      Volume: 209 Pages: 351-359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Journal Article] Endogenous acetylcholine modulates impulsive action via alpha4beta2 nicotinic acetylcholine receptors in rats2010

    • Author(s)
      Tsutsui-Kimura I, Ohmura Y, Izumi T, Yamaguchi T, Yoshida T, Yoshioka M
    • Journal Title

      Eur J Pharmacol

      Volume: 641 Pages: 148-153

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591477
  • [Journal Article] Endogenous acetylcholine modulates impulsive action via alpha4beta2 nicotinic acetylcholine receptors in rats2010

    • Author(s)
      Isutsui-Kimura I, Ohmura Y, Izumi T, Yamaguchi T, Yoshida T, Yoshioka M
    • Journal Title

      Eur J Pharmacol

      Volume: 641 Pages: 148-153

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Journal Article] Nicotine provokes impulsive-like action by stimulating alpha4beta2 nicotinic acetylcholine receptors in the infralimbic, but not in the prelimbic cortex2010

    • Author(s)
      Tsutsui-Kimura I, Ohmura Y, Izumi T, Yamaguchi T, Yoshida T, Yoshioka M.
    • Journal Title

      Psychopharmacology (Berl)

      Volume: 209(4) Pages: 351-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Journal Article] Diazepam-induced increases of synaptic efficacy in the hippocampal-mPFC pathway are associated with its anxiolytic-like effect of rat2010

    • Author(s)
      Shikanai H, Izumi T, Matsumoto M, Togashi H, Yamaguchi T, Yoshida T, Yoshioka M
    • Journal Title

      J Pharmacol Sci

      Volume: 114 Pages: 341-346

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591477
  • [Journal Article] Nicotine provokes impulsive-like action by stimulating alpha4beta2 nicotinic acetylcholine receptors in the infralimbic, but not in the prelimbic cortex2010

    • Author(s)
      Tsutsui-Kimura I, Ohmura Y, Izumi T, Yamaguchi T, Yoshida T, Yoshioka M
    • Journal Title

      Psychopharmacology

      Volume: 209 Pages: 351-359

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591477
  • [Journal Article] Corticotropin releasing factor enhances attentional function as assessed by the five-choice serial reaction time task in rats2009

    • Author(s)
      Ohmura Y, Yamaguchi T, Futami Y, Togashi H, Izumi T, Matsumoto M, Yoshida T, Yoshioka M.
    • Journal Title

      Behav Brain Res

      Volume: 198(2) Pages: 429-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Journal Article] Togashi H: Possible relationship between the stress-induced synaptic response and metaplasticity in the hippocampal CA1 field of freely moving rats2009

    • Author(s)
      Hirata R, Matsumoto M, Judo, C, Yamaguchi T, Izumi T, Yoshioka M
    • Journal Title

      Synapse 63

      Pages: 549-556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591335
  • [Journal Article] Early postnatal stress affects 5-HT1A receptor function in the medial prefrontal cortex in adult rats2009

    • Author(s)
      Matsuzaki H, Izumi T, Matsumoto M, Togashi H, Yamaguchi T, Yoshida T, Watanabe M, Yoshioka M
    • Journal Title

      Eur J Pharmacol

      Volume: 615 Pages: 76-82

    • NAID

      120001452160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591477
  • [Journal Article] The effects of serotonin and/or noradrenaline reuptake inhibitors on impulsive-like action assessed by the three-choice serial reaction time task : a simple and valid model of impulsive action using rats2009

    • Author(s)
      Tsutsui-Kimura I, Ohmura Y, Izumi T, Yamaguchi T, Yoshida T, Yoshioka M.
    • Journal Title

      Behav Pharmacol

      Volume: 20(5-6) Pages: 474-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Journal Article] The effects of serotonin and/or noradrenaline reuptake inhibitors on impulsive-like action assessed by the three-choice serial reaction time task : a simple and valid model of impulsive action using rats2009

    • Author(s)
      Tsutsui-Kimura I, Ohmura Y, Izumi T, Yamaguchi T, Yoshida T, Yoshioka M
    • Journal Title

      Behav Pharmacol

      Volume: 20 Pages: 474-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591477
  • [Journal Article] 社会不安障害(SAD)の生物学的基盤2009

    • Author(s)
      泉剛
    • Journal Title

      医薬ジャーナル 45

      Pages: 2094-2097

    • Data Source
      KAKENHI-PROJECT-20390309
  • [Journal Article] 社会不安障害の脳機能と薬物療法2009

    • Author(s)
      泉剛
    • Journal Title

      臨床精神薬理 12

      Pages: 193-1937

    • Data Source
      KAKENHI-PROJECT-20390309
  • [Journal Article] Early postnatal stress alters the extinction of context-dependent conditioned fear in adult rats2008

    • Author(s)
      Matsumoto M, Togashi H, Konnno K, Koseki H, Hirata R, Izumi T, Yamaguchi T, Yoshioka M
    • Journal Title

      Pharmacology, Biochemistry and Behavior 89

      Pages: 247-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591335
  • [Journal Article] Characterization of clozapine-induced changes in synaptic plasticity in the hippocampal-mPFC pathway of anesthetized rats2008

    • Author(s)
      Matsumoto M, Shikanai H, Togashi H, Izumi T, Kitta T, Hirata R, Yamaguchi T, Yoshioka M
    • Journal Title

      Brain Research 1195

      Pages: 50-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591335
  • [Journal Article] Changes in amygdalaneural activity that occur with the extinction of context-dependent conditioned fear stress2008

    • Author(s)
      Takeshi Izumi
    • Journal Title

      Pharmacology Biochemistry Bihavior 90巻

      Pages: 297-304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591334
  • [Journal Article] Characterization of stress-induced suppression of long-term potentiation in the hippocampal CA1 field of freely moving rats2008

    • Author(s)
      Hirata,R Togashi H, Matsumoto M, Yamaguchi T, Izumi T, Yoshioka M:
    • Journal Title

      Brain Reseach 1226

      Pages: 27-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591335
  • [Journal Article] Changes in amygdala neural activity that occur with the extinction of context-dependent conditioned fear stress.2008

    • Author(s)
      Takeshi Izumi
    • Journal Title

      Pharmacology Biochemistry Bihavior (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591334
  • [Journal Article] Early postnatal stress affects the serotonergic function in the median raphe nuclei of adult rats2007

    • Author(s)
      Konno K, Matsumoto M, Togashi H, Yamaguchi T, Izumi T, Watanabe M, Iwanaga T, Yoshioka M
    • Journal Title

      Brain Research 1172

      Pages: 60-66

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591335
  • [Journal Article] Effects of aversive stress during brain development on hippocampal synaptic and behavioral responses to emotional stress at postadolescence2007

    • Author(s)
      Koseki H, Matsumoto M, Togashi H, Yamaguchi T, Izumi T, Yoshioka M
    • Journal Title

      Nihon Shinkei Seishin Yakurigaku Zasshi 27

      Pages: 19-27

    • NAID

      10023963924

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591335
  • [Presentation] ニワトリ胚のニコチン性アセチルコリン受容体伝達の阻害は 孵化後の雛に自閉症様の視知覚発達の不全をもたらす2023

    • Author(s)
      松島俊也、三浦桃子、Giorgio Vallortigara、泉 剛
    • Organizer
      日本神経精神薬理学会第53回年会
    • Data Source
      KAKENHI-PROJECT-22K07622
  • [Presentation] 海馬におけるオレキシン受容体の発現と情動制御機能2023

    • Author(s)
      尾崎 和音、鹿内 浩樹、篠塚 賢志、馬渕 莉穂、進藤 つぐみ、 大橋 敦子、泉 剛
    • Organizer
      第36回北海道薬物作用談話会
    • Data Source
      KAKENHI-PROJECT-22K07622
  • [Presentation] 海馬オレキシン受容体によるうつ様行動の制御2023

    • Author(s)
      尾崎 和音、鹿内 浩樹、馬渕 莉穂、進藤 つぐみ、大橋 敦子、泉 剛
    • Organizer
      日本薬学会北海道支部第150回例会
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] うつ病モデル動物における海馬テロメアの異常短縮2023

    • Author(s)
      鹿内 浩樹、進藤 つぐみ、尾崎 和音、大橋 敦子、大塚 郁夫、菱本 明豊、泉 剛
    • Organizer
      第97回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] 海馬におけるオレキシン受容体の発現と情動制御機能2023

    • Author(s)
      尾崎 和音、鹿内 浩樹、篠塚 賢志、馬渕 莉穂、進藤 つぐみ、大橋 敦子、泉 剛
    • Organizer
      第36回北海道薬物作用談話会
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] うつ病モデル動物における海馬テロメアの異常短縮2023

    • Author(s)
      鹿内浩樹、進藤つぐみ、尾崎和音、大橋敦子、泉 剛
    • Organizer
      第97回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K07622
  • [Presentation] SSRIの抗不安作用の機序ー脳内セロトニン神経系について2022

    • Author(s)
      泉 剛、今野幸太郎、渡辺雅彦、田中謙二、鹿内浩樹
    • Organizer
      第14回日本不安症学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K07622
  • [Presentation] うつ病モデル動物の大脳辺縁系における下垂体ホルモン受容体mRNA発現解析2022

    • Author(s)
      中井 慎一, 鹿内 浩樹, 大橋 敦子, 泉 剛
    • Organizer
      日本薬学会北海道支部第149回例会
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] うつ病モデル動物におけるテロメア2022

    • Author(s)
      鹿内浩樹、進藤つぐみ、尾崎和音、大橋敦子、大塚郁夫、菱本明豊、泉剛
    • Organizer
      BPCNPNPPP4学会合同年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K07622
  • [Presentation] AD/HDの薬物治療の新しい戦略2022

    • Author(s)
      鹿内浩樹、進藤つぐみ、平出幸子、木村真一、飯塚健治、泉 剛
    • Organizer
      第96回日本薬理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K07622
  • [Presentation] SSRIの抗不安作用の機序―脳内セロトニン神経系について2022

    • Author(s)
      泉 剛, 今野 幸太郎, 渡辺 雅彦, 田中 謙二, 鹿内 浩樹
    • Organizer
      第14回日本不安症学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] うつ病モデル動物におけるテロメア2022

    • Author(s)
      鹿内 浩樹, 進藤 つぐみ, 尾崎 和音, 大橋 敦子, 大塚 郁夫, 朴 秀賢, 菱本 明豊, 泉 剛
    • Organizer
      第52回日本神経精神薬理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] うつ病における海馬オレキシン受容体の関与2022

    • Author(s)
      鹿内 浩樹, 進藤 つぐみ, 尾崎 和音, 馬渕 莉穂, 中井 慎一, 大橋 敦子, 泉 剛
    • Organizer
      第73回日本薬理学会北部会
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] うつ病における海馬オレキシン神経系の関与2022

    • Author(s)
      鹿内浩樹、進藤つぐみ、尾崎和音、馬渕莉穂、中井慎一、大橋敦子、泉剛
    • Organizer
      第73回日本薬理学会北部会
    • Data Source
      KAKENHI-PROJECT-22K07622
  • [Presentation] 幼若期ストレス負荷うつ病モデル動物の脳内GSK-3β/β-cateninシグナルの異常2022

    • Author(s)
      尾崎 和音、進藤 つぐみ、日下 翔太、脇田 征太朗、鹿内 浩樹、 大橋 敦子、泉 剛
    • Organizer
      第35回北海道薬物作用談話会
    • Data Source
      KAKENHI-PROJECT-22K07622
  • [Presentation] AD/HDの薬物治療の新しい戦略 -New drug treatment strategies for AD/HD-2022

    • Author(s)
      鹿内 浩樹, 進藤 つぐみ, 平出 幸子, 木村 真一, 飯塚 健治, 泉 剛
    • Organizer
      第96回日本薬理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] うつ病モデル動物の恐怖記憶消去障害に対するリルゾールの効果2022

    • Author(s)
      葛西 里菜, 鹿内 浩樹, 日下 翔太, 進藤 つぐみ, 大橋 敦子, 泉 剛
    • Organizer
      日本薬学会北海道支部第149回例会
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] うつ病モデル動物の海馬におけるGSK3β/β-cateninシグナルの異常解析2022

    • Author(s)
      日下 翔太, 脇田 征太朗, 進藤 つぐみ, 尾崎 和音, 鹿内 浩樹, 大橋 敦子, 泉 剛
    • Organizer
      日本薬学会北海道支部第149回例会
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] 幼若期ストレス負荷うつ病モデル動物の脳内 GSK3β/β-cateninシグナルの異常2022

    • Author(s)
      尾崎 和音, 進藤 つぐみ, 日下翔太, 脇田 征太朗, 鹿内 浩樹, 大橋 敦子, 泉 剛
    • Organizer
      第35回北海道薬物作用談話会
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] うつ病モデル動物の脳内 Akt-mTOR および GSK3β系の異常解析2021

    • Author(s)
      進藤 つぐみ、脇田 征太朗、尾崎 和音、高津 誠也、鹿内 浩樹、大橋 敦子、泉 剛
    • Organizer
      第34回北海道薬物作用談話会
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] うつ病モデル動物における脳内Akt-mTOR シグナルの異常2021

    • Author(s)
      進藤 つぐみ、鹿内 浩樹、高津 誠也、脇田 征太朗、泉 剛
    • Organizer
      第51回日本神経精神薬理学会
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] うつ病モデル動物における前頭前野および皮質辺縁系Aktシグナルの異常2021

    • Author(s)
      進藤 つぐみ、鹿内 浩樹、高津 誠也、大橋 敦子、泉 剛
    • Organizer
      第68回北海道薬学大会
    • Data Source
      KAKENHI-PROJECT-19K08079
  • [Presentation] うつ病モデル動物における前頭前野および皮質辺縁系 Akt シグナルの異常2021

    • Author(s)
      進藤 つぐみ、鹿内 浩樹、高津 誠也、大橋 敦子、泉 剛
    • Organizer
      日本薬学会北海道支部第148回例会
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] うつ病モデル動物における脳内Akt-mTORシグナルの異常2021

    • Author(s)
      進藤つぐみ、鹿内浩樹、高津誠也、泉 剛
    • Organizer
      第51回 日本神経精神薬理学会
    • Data Source
      KAKENHI-PROJECT-19K08079
  • [Presentation] うつ病モデル動物の脳内Akt-mTORおよびGSK3β系の異常解析2021

    • Author(s)
      進藤 つぐみ、脇田 征太朗、尾崎 和音、高津 誠也、鹿内 浩樹、大橋 敦子、泉 剛
    • Organizer
      第34回北海道薬物作用談話会
    • Data Source
      KAKENHI-PROJECT-19K08079
  • [Presentation] うつ病モデル動物における脳内Akt-mTOR/GSK-3β シグナルの異常2021

    • Author(s)
      進藤 つぐみ、鹿内 浩樹、高津 誠也、脇田 征太朗、泉 剛
    • Organizer
      次世代を担う若手のための創薬・医療薬理シンポジウム2021
    • Data Source
      KAKENHI-PROJECT-21K07506
  • [Presentation] Local injection of D-amino acid oxidase inhibitor to the prefrontal cortex improves AD/HD-like behaviors of SHRSP/Ezo.2020

    • Author(s)
      Hiroki Shikanai, Tsugumi Shindo, Sachiko Hiraide, Kenji Iizuka, Takeshi Izumi
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19K08079
  • [Presentation] SSRI exerts anxiolytic effect via 5-HT1A and 5-HT2A receptors in the amygdala2019

    • Author(s)
      Izumi T, Konno K, Watanabe M, Tanaka K, Yoshida T, Shikanai H, Yoshioka M
    • Organizer
      Society for Neuroscience Annual Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08079
  • [Presentation] 5-HT1A and 5-HT2A receptors in the amygdala, as target molecules of the anxiolytic action of SSRIs2019

    • Author(s)
      Izumi T, Konno K, Watanabe M, Tanaka K, Yoshida T, Shikanai H, Yoshioka M
    • Organizer
      第92回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19K08079
  • [Presentation] うつ病モデル動物における扁桃体FKBP5の発現様式2019

    • Author(s)
      鹿内浩樹、Rebel Ghebreab、吉田 隆行、菱本 明豊、吉岡 充弘、泉 剛
    • Organizer
      第49回日本神経精神薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19K08079
  • [Presentation] Loss of chromosome Y in blood, but not in brain, of suicide completers.2018

    • Author(s)
      Otsuka I, Okazaki S, Kimura A, Horai T, Izumi T, Takahashi M, Ueno Y, Shirakawa O, Sora I, Hishimoto A.
    • Organizer
      WFSBP Asia Pacific Regional Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04249
  • [Presentation] The role of the brain FKBP5 in depression2018

    • Author(s)
      Takeshi Izumi, Robel Ghebreab, Ce Wang, Takayuki Yoshida, Hiroki Shikanai, Akitoyo Hishimoto, Mitsuhiro Yoshioka
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10183
  • [Presentation] 幼若期ストレスによる視床下部-下垂体-;副腎(HPA)系の機能変化2017

    • Author(s)
      王册、泉剛、吉田隆行、大村優、吉岡充弘
    • Organizer
      第90回日本薬理学会
    • Data Source
      KAKENHI-PROJECT-16K10183
  • [Presentation] Juvenile stress-induced intrinsic membrane plasticity in the mouse amygdaloid pyramidal neurons2016

    • Author(s)
      Takayuki Yoshida, Midori Kobie, Yukihiro Fujita, Yu Ohmura, Takeshi Izumi, Mitsuhiro Yoshioka
    • Organizer
      The 39th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-16H05371
  • [Presentation] SSRIの抗不安効果は扁桃体5-HT1Aおよび5-HT2A受容体を介する2016

    • Author(s)
      泉 剛、王 冊、大村 優、吉田 隆行、吉岡 充弘
    • Organizer
      第67回日本薬理学会北部会
    • Place of Presentation
      北海道大学学術交流会館(北海道・札幌市)
    • Data Source
      KAKENHI-PROJECT-16H05371
  • [Presentation] 幼若期ストレスによる視床下部-下垂体-副腎(HRA)系の機能変化2016

    • Author(s)
      王 冊、泉 剛、吉岡 充弘
    • Organizer
      第67回日本薬理学会北部会
    • Place of Presentation
      北海道大学学術交流会館(北海道・札幌市)
    • Data Source
      KAKENHI-PROJECT-16H05371
  • [Presentation] ミルナシプラン反復投与は衝動性亢進ラットを改善する2014

    • Author(s)
      木村生、大村 優、吉田隆行、泉 剛、吉岡充弘
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台国際センタ-(仙台市)
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Presentation] Repeated milnacipran ameliorates rats with elevated impulsivityミルナシプラン反復投与は衝動性亢進ラットを改善する2014

    • Author(s)
      木村 生, 大村 優, 吉田隆行, 泉 剛, 吉岡充弘
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台市 仙台国際センタ-
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Presentation] Effects of repeated restrain stress on depression and anxiety like behaviors,and On glucocorticoid receptor function in the rat brain2013

    • Author(s)
      Robel Ghebreab、Takeshi Izumi、Takayuki Yoshida,Yu Ohmura、Mitsuhiro
    • Organizer
      第129回日本薬理学会関東部会
    • Place of Presentation
      順天堂大学本郷キャンパス(東京都)
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Presentation] 扁桃体におけるセロトニンおよびカンナビノイドシグナル伝達系の相互調節機構2013

    • Author(s)
      吉田隆行、今野幸太郎、内ヶ島基政、大村 優、泉 剛、渡辺雅彦、吉岡充弘
    • Organizer
      第36回日本神経科学大会 第56回日本神経化学会大会 第23回日本神経回路学会大会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Presentation] 扁桃体におけるセロトニンおよびカンナビノイドシグナル伝達系の相互調節機構2013

    • Author(s)
      吉田隆行, 今野幸太郎, 内ヶ島基政, 大村 優, 泉 剛, 渡辺雅彦, 吉岡充弘
    • Organizer
      第36回日本神経科学大会 第56回日本神経化学会大会第23回日本神経回路学会大会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Presentation] The effects of repeated restrain stress on expression of glucocorticoid receptor and FKBP5 in the brain2013

    • Author(s)
      Robel Ghebreab, Takeshi Izumi, Takayuki Yoshida, Yu Ohmura, MitsuhiroY oshioka
    • Organizer
      第64回日本薬理学会北部会
    • Place of Presentation
      旭川市大雪クリスタルホ-ル
    • Year and Date
      2013-09-13
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Presentation] Effects of repeated restrain stress on depression and anxiety like behaviors, andOn glucocorticoid receptor function in the rat brain2013

    • Author(s)
      Robel Ghebreab, Takeshi Izumi, Takayuki Yoshida, Yu Ohmura, Mitsuhiro Yoshioka
    • Organizer
      第129回日本薬理学会関東部会
    • Place of Presentation
      順天堂大学 本郷キャンパス
    • Year and Date
      2013-10-19
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Presentation] 腹側海馬におけるセロトニン-7 受容体は恐怖記憶の想起に関与しているSerotonin-7(5-HT7) receptor in the ventral hippocampus is involved in the Retrieval of fear memory2012

    • Author(s)
      大村 優, 吉田隆行, 泉 剛, 吉岡充弘
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      Neuroscience 2012 名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Presentation] SSRI exerts anxiolytic effect via 5-HT1A receptors in the basolateral nucleus of amygdala2012

    • Author(s)
      Takeshi Izumi, Takayuki Yoshida, Hirokazu Matsuzaki, Kotaro Konno, Kenji F . Tanaka, Hiroki Shikanai, Y u Ohmura, MasahikoWatanabe, Mitsuhiro Yoshioka
    • Organizer
      Neuroscience 2012 米国 ニュ-オ-リンズ
    • Place of Presentation
      Ernest N.Morial Convention Center
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Presentation] SSRI exerts anxiolytic effect via 5-HT1A receptors in the basolateral nucleus of amygdala2012

    • Author(s)
      Izumi T
    • Organizer
      Society for Neuroscience 42nd Annual Meeting
    • Place of Presentation
      Ernest N/Morial Convention Center(USA)
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Presentation] SSRI exerts anxiolytic effect via 5-HT1A receptors in the basolateral nucleus of amygdala2012

    • Author(s)
      Izumi T
    • Organizer
      Society for Neuroscience 42nd Annual Meeting
    • Place of Presentation
      Ernest N.Morial Convention Center(米国)
    • Data Source
      KAKENHI-PROJECT-24591674
  • [Presentation] Tandospirone supptrsses impulsive action in rats2012

    • Author(s)
      Yu Ohmura, Haruko Kumamoto, Iku Tsusui-Kimura, Takeshi Izumi, Takayuki Yoshida, Mitsuhiro Yoshioka
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2012-03-16
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Presentation] 扁桃体における不安発現に対する5-HT作動性神経の調節メカニズム2011

    • Author(s)
      泉剛
    • Organizer
      第41回神経精神薬理学
    • Place of Presentation
      東京、京王プラザホテル
    • Year and Date
      2011-10-27
    • Data Source
      KAKENHI-PROJECT-21591477
  • [Presentation] 扁桃体における不安発現に対する5-HT作動性神経の調節メカニズム2011

    • Author(s)
      泉剛
    • Organizer
      第41回神経精神薬理学会
    • Place of Presentation
      京王プラザホテル(東京)(招待講演)
    • Year and Date
      2011-10-27
    • Data Source
      KAKENHI-PROJECT-21591477
  • [Presentation] 扁桃体における不安発現に対する5-HT作動性神経の調節メカニズム2011

    • Author(s)
      泉剛、吉岡充弘
    • Organizer
      第21回日本臨床精神薬理学会第41回日本神経精神薬理学会年会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2011-10-27
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Presentation] 内側前頭前野腹側部α4β2ニコチン性アセチルコリン受容体の衝動的行動における役割2011

    • Author(s)
      木村生, 大村優, 泉剛, 山口拓, 吉田隆行, 吉岡充弘
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-03-22
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Presentation] 背側縫線核におけるGABA合成酸素GAD67含有5-HT作動性ニューロンの細胞特性2011

    • Author(s)
      鹿内浩樹、吉田隆行、今野幸太郎、泉剛、大村優、渡邉雅彦、吉岡充弘
    • Organizer
      第62回日本薬理学会北部会
    • Place of Presentation
      江陽グランドホテル(宮城)
    • Year and Date
      2011-09-29
    • Data Source
      KAKENHI-PROJECT-23390284
  • [Presentation] 縫線核5-HT/GAD67共発現ニューロンの細胞学的特性2010

    • Author(s)
      鹿内浩樹,吉田隆行,今野幸太郎,泉剛,山口拓,吉岡充弘
    • Organizer
      第24回北海道薬物作用談話会
    • Place of Presentation
      北海道大学学術交流会館
    • Year and Date
      2010-07-24
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Presentation] 両側扁桃体5-HT神経終末破壊が不安関連行動に及ぼす効果2010

    • Author(s)
      泉剛
    • Organizer
      第20回日本神経精神薬理学
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2010-09-17
    • Data Source
      KAKENHI-PROJECT-21591477
  • [Presentation] 両側扁桃体5-HT神経終末破壊が不安関連行動に及ぼす効果2010

    • Author(s)
      泉剛
    • Organizer
      第20回日本神経精神薬理学会
    • Place of Presentation
      仙台国際センター(宮城)
    • Year and Date
      2010-09-17
    • Data Source
      KAKENHI-PROJECT-21591477
  • [Presentation] 両側扁桃体5-HT神経末破壊が不安関連行動に及ぼす効果2010

    • Author(s)
      泉剛
    • Organizer
      第83回日本薬理学年会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Presentation] 成熟ラットにおける正中縫線核5-HT神経およびGABA神経機能に及ぼす幼若期ストレスの影響2010

    • Author(s)
      今野幸太郎,松本真知子,泉剛,富樫廣子,吉田隆行,山口拓,長谷川宏幸,渡辺雅彦,吉岡充弘
    • Organizer
      第33回日本神経科学大会・第53回日本神経化学会大会・第20回日本神経回路学会大会合同年会
    • Place of Presentation
      神戸コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Presentation] 両側扁桃体5-HT神経終末破壊が不安関連行動に及ぼす効果2010

    • Author(s)
      泉剛
    • Organizer
      第83回日本薬理学年会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-21591477
  • [Presentation] 条件付け恐怖で活性化される扁桃体基底外側核および間在核神経細胞の性質2009

    • Author(s)
      泉剛
    • Organizer
      第39回日本神経精神薬理学会
    • Place of Presentation
      国立京都国際会議場(京都市)
    • Year and Date
      2009-11-13
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Presentation] Effect of bilateral lesion of the amygdala 5-HT terminals on the anxiety-related behaviors in rats2009

    • Author(s)
      泉剛
    • Organizer
      第83回日本薬理学会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2009-03-17
    • Data Source
      KAKENHI-PROJECT-21591477
  • [Presentation] Characterization and functional meaning of the conditioned fear-related neural cells in the basolateral amygdala2009

    • Author(s)
      泉 剛
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-19591334
  • [Presentation] Characterization of conditioned fear-induced c-Fos and phosphorylated CREB-positive cells in the basolateral amygdala2009

    • Author(s)
      Takeshi Izumi
    • Organizer
      22^<nd> ECNP Congress
    • Place of Presentation
      Istanbul Convention & Exhibition Centre(イスタンブール、トルコ)
    • Year and Date
      2009-09-15
    • Data Source
      KAKENHI-PROJECT-20390309
  • [Presentation] Effect of fluvoxamine on the evoked field potentials in the basal amygdala inducad by perirhinal cortex stimulation in vivo2008

    • Author(s)
      泉 剛
    • Organizer
      第81回日本薬理学会
    • Place of Presentation
      パシフィコ横浜会議センター
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-19591334
  • [Presentation] Effect of fluvoxamine on the evoked field potentials in the basal amygdala induced by perirhinal cortex stimulation in vivo2008

    • Author(s)
      泉 剛
    • Organizer
      第81回日本薬理学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-19591334
  • [Presentation] Evoked field potentials of the basal amygdale induced by perirhinal cortex stimulation2007

    • Author(s)
      泉 剛
    • Organizer
      第37回日本神経精神薬理学会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2007-07-13
    • Data Source
      KAKENHI-PROJECT-19591334
  • [Presentation] The role of amygdalar serotonergic neural system in fear memory

    • Author(s)
      Izumi T, Ohmura Y, Yoshida T, Yoshioka M
    • Organizer
      44th Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      Washington DC, U.S.A.
    • Year and Date
      2014-11-15 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-24591674
  • 1.  YOSHIOKA Mitsuhiro (40182729)
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  • 2.  YAMAGUCHI Taku (80325563)
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    # of Collaborated Projects: 1 results
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  • 15.  Toda Hiroyuki (00610677)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  白川 治 (40243307)
    # of Collaborated Projects: 1 results
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  • 19.  KOBAYASHI kazuto
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  • 20.  NAKAGAWA shin
    # of Collaborated Projects: 1 results
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  • 21.  Hiroi Noboru
    # of Collaborated Projects: 1 results
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  • 22.  白河 治
    # of Collaborated Projects: 0 results
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  • 23.  谷垣 健二
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  • 24.  菊水 健史
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