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HIGASHI Michiyo  東 美智代

ORCIDConnect your ORCID iD *help
… Alternative Names

東 美智代  ヒガシ ミチヨ

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Researcher Number 60315405
Other IDs
External Links
Affiliation (Current) 2025: 鹿児島大学, 医歯学域鹿児島大学病院, 准教授
Affiliation (based on the past Project Information) *help 2019 – 2024: 鹿児島大学, 医歯学域鹿児島大学病院, 准教授
2017 – 2018: 鹿児島大学, 医歯学域附属病院, 准教授
2017: 鹿児島大学, 医歯学域付属病院, 准教授
2015 – 2016: 鹿児島大学, 医歯学域医学系, 准教授
2012 – 2014: 鹿児島大学, 医歯(薬)学総合研究科, 准教授 … More
2013: 鹿児島大学, 医歯学総合研究科, 准教授
2011: 鹿児島大学, 大学院・医歯学総合研究科, 講師
2010 – 2011: 鹿児島大学, 医歯学総合研究科, 講師
2009: Kagoshima University, 大学院・医歯学総合研究科, 講師
2007 – 2008: 鹿児島大学, 大学院・医歯学総合研究科, 助教
2005 – 2006: 鹿児島大学, 大学院医歯学総合研究科, 助手
2000: 鹿児島大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Human pathology / Basic Section 49020:Human pathology-related
Except Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Biological Sciences / Radiation science / Human pathology / Basic Section 90140:Medical technology assessment-related / Basic Section 52040:Radiological sciences-related / Basic Section 55020:Digestive surgery-related / Basic Section 49020:Human pathology-related / Human pathology / Tumor diagnostics
Keywords
Principal Investigator
ムチン抗原 / 病理学 / MUC4 / MUC1 / 予後因子 / 膵胆道腫瘍 / 病理 / 膵胆道系腫瘍 / prognosis / methylation … More / MUC / 膵胆管系腫瘍 / 早期診断 / MUC16 / ムチン / 機械学習 / バイオマーカー / 治療効果判定 / メチル化 / 予後 / MUC2 / MUC17 … More
Except Principal Investigator
DNAメチル化 / ムチン / 予後 / MUC4 / DNA methylation / 膵癌 / MUC1 / MUC2 / 予後予測 / 機械学習 / 胆管癌 / 膵臓癌 / ヒストン修飾 / 予後因子 / prognosis prediction / BSAS / NGS / cholangiocarcinoma / 治療効果 / 膵胆管系腫瘍 / mucin / IPMN / エピジェネティクス / 肝内胆管癌 / MUC16 / MUC5AC / クロマチン免疫沈降法 / DNAメチル化定量解析システム / 膵胆管系癌 / 免疫染色 / 人工肛門 / 肛門温存手術 / 直腸癌 / TaTME / プルスルー法 / 判別モデル / 個別化医療 / 診断能 / CEST画像 / MPS / PDAC / バイオマーカー / 予防医学 / ゲノム医療 / クローン進化 / クローン拡大 / 予防 / ゲノム / 早期診断 / 発癌 / リキッドバイオプシ / 早期発見 / 次世代シークエンサー / DNA methyaltion / DNAメチル化 / 次世代シークエンス / 予測モデル / 転写制御 / 乳癌 / アロマターゼ / 酸素代謝強調MR画像 / PET / 治療効果予測 / 化学療法 / 放射線療法 / 酸素代謝強調画像 / 切除不能膵臓癌 / 酸素代謝 / MRI / CT / 放射線化学療法 / microdissection / operative indication / prognosis of patient with cancer / clinicopathological factor / immunohistochemistry / pancreatobiliary tumor / 分子病理学的 / 組織型 / 分子病理学 / MUC2ムチン / MUC1ムチン / 肝外胆管癌 / 膵管内乳頭腫瘍 / 胆管腫瘍 / 膵腫瘍 / マイクロディセクション / 手術適応 / 癌患者の予後 / 臨床病理学的因子 / 免疫組織学 / 門脈塞栓 / 脂肪肝 / 門脈塞栓術 / 膵液 / 膵臓 / がんの個性診断 / DANメチル化 / MUC17 / 低酸素応答性 / 悪性度 / gastric-type IPMN / intestinal-type IPMN / 異常糖鎖修飾 / angiogenesis / diagnosis / 転写後翻訳阻害 / マイクロRNA / ヒストン化学修飾 / 粘液産生胆管腫瘍 / 膵管内乳頭粘液性腫瘍 / 唾液腺 / 消化器 / リスク評価 / ヒト癌 / methvlation specific PCR / micropapillary pattern / 肺腺癌 / ヒストン修飾状態 / 膵癌細胞株 Less
  • Research Projects

    (21 results)
  • Research Products

    (169 results)
  • Co-Researchers

    (48 People)
  •  機械学習を用いた胆管癌悪性度予測モデルの構築

    • Principal Investigator
      横山 勢也
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kagoshima University
  •  Pull-through coloanal anastomosis after sphincter preserving ultra-low anterior resection without diverting ileostomy for lower rectal cancer

    • Principal Investigator
      盛 真一郎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90140:Medical technology assessment-related
    • Research Institution
      Kagoshima University
  •  Biomarker investigation of Pancreatobiliary neoplasm for early diagnosis and tratmentPrincipal Investigator

    • Principal Investigator
      Higashi Michiyo
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Kagoshima University
  •  Construction of DNA Methylation Markers for liqid biopsy of Pancreatic Cancer.

    • Principal Investigator
      Yokoyama Seiya
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kagoshima University
  •  CEST画像による膵癌の分子イメージングとこれを用いた非造影膵MR診断法の確立

    • Principal Investigator
      福倉 良彦
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Kawasaki Medical School
      Kagoshima University
  •  Genetic assessments to detect patients requiring prophylactic total pancreatectomy for the prevention of pancreatic cancer.

    • Principal Investigator
      Ohtsuka Takao
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kagoshima University
  •  Basic research for the development of novel aromatase inhibitors against breast cancer

    • Principal Investigator
      Hamada Taiji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Kagoshima University
  •  Establishment of early diagnosis and treatment effect prediction method for pancreatobiliary neoplasmPrincipal Investigator

    • Principal Investigator
      Higashi Michiyo
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Kagoshima University
  •  A fundamental study for construction of bile duct cancer early diagnosis method by DNA methylation analysis.

    • Principal Investigator
      Yokoyama Seiya
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kagoshima University
  •  Attempt to establishment of early diagnosis and prediction of therapeutic response in pancreatobiliary neoplasmsPrincipal Investigator

    • Principal Investigator
      HIGASHI Michiyo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Kagoshima University
  •  Blood oxygenation level-dependent contrast magnetic resonance imaging for prediction of overall survival in patients with pancreatic adenocarcinoma after chemoradiotherapy

    • Principal Investigator
      Fukukura Yoshihiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Kagoshima University
  •  膵液を用いた新規メチル化解析法による膵癌の早期診断予測法の構築

    • Principal Investigator
      米澤 傑
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor diagnostics
    • Research Institution
      Kagoshima University
  •  Experimental study of selective portal vein embolization for nonalcoholic steatohepatitis in rabbit model

    • Principal Investigator
      hayashi sadao
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Kagoshima University
  •  Establishment of early diagnosis of pabcreatobiliary neoplasmPrincipal Investigator

    • Principal Investigator
      HIGASHI Michiyo
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Kagoshima University
  •  Establishment of early diagnosis system of pancreatobiliary carcinomas by the application of mucin expression profiles

    • Principal Investigator
      YONEZAWA Suguru
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      Kagoshima University
  •  Investigation of prognostic factor in pancreatobiliary neoplasmPrincipal Investigator

    • Principal Investigator
      HIGASHI Michiyo
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Kagoshima University
  •  ヒト癌のリスク評価に普遍的に関連するムチン抗原の遺伝子発現機構の解明

    • Principal Investigator
      米澤 傑
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kagoshima University
  •  Mucin gene expression mechanism related to a new classification of pancreatobiliary neoplasms

    • Principal Investigator
      YONEZAWA Suguru
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Kagoshima University
  •  ヒト腺癌のリスク評価に普遍的に関連するムチン抗原の特定

    • Principal Investigator
      米澤 傑
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kagoshima University
  •  膵胆管系癌患者のリスクに関連するムチン抗原の特定とその遺伝子発現機構の解明

    • Principal Investigator
      YONEZAWA Suguru
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kagoshima University
  •  Re-classification of pancreatobiliary tumors by mucin expression profile - An application to the operative indication -

    • Principal Investigator
      YONEZAWA Suguru
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      Kagoshima University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book Patent

  • [Book] 胆と膵 IPMN大全 IPMNの歴史的変遷 IPMNにおけるMUC発現とその評価の歴史2020

    • Author(s)
      東美智代、横山勢也、米澤傑、谷本昭英
    • Total Pages
      58
    • Publisher
      医学図書出版
    • ISBN
      9784865173956
    • Data Source
      KAKENHI-PROJECT-18K07019
  • [Book] 膵腫瘍におけるムチンコア蛋白(MUC)の分子病理 (分担執筆), 専門医のための消化器病学第2版. (小俣政男, 千葉勉;監修, 下瀬川徹, 渡辺守, 木下芳一, 金子周一, 樫田博史;編集)2013

    • Author(s)
      米澤 傑, 東美智代
    • Total Pages
      686
    • Publisher
      医学書院, 東京
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Book] 膵腫瘍におけるムチンコア蛋白(MUC)の分子病理 (分担執筆), 専門医のための消化器病学第2版.(小俣政男、千葉勉;監修2013

    • Author(s)
      米澤 傑、東美智代
    • Total Pages
      686
    • Publisher
      医学書院、東京
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Book] 専門医のための消化器病学第2版(小俣政男、千葉勉監修)、膵腫瘍におけるムチンコア蛋白(MUC)の分子病理(分担)2013

    • Author(s)
      米澤傑、東美智代
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-24590447
  • [Book] Extrahepatic bile duct carcinoma : Mucin 4, a poor prognostic factor2011

    • Author(s)
      Higashi, M., et al.
    • Publisher
      Springer Publishing(印刷中)
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Book] Extrahepatic bile duct carcinoma : Mucin 4, a poor prognostic factor2011

    • Author(s)
      Higashi, M., et al.
    • Publisher
      Springer Publishing(印刷中)
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Book] 病理診断に役立つ分子生物学(病理と臨床臨時増刊号 Vol.29) (分担執筆), 第 2 部 病理診断医になじみのある疾患関連分子, MUC 解説編. (金井弥栄, 石川俊平, 池田栄二;編集)2011

    • Author(s)
      米澤 傑, 山田宗茂, 横山勢也, 北本 祥, 田畑和宏, 東美智代
    • Total Pages
      545
    • Publisher
      株式会社文光堂
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Book] 病理診断に役立つ分子生物学(病理と臨床臨時増刊号 Vol.29) (分担執筆), 第 2 部 病理診断医になじみのある疾患関連分子, MUC 診断編. (金井弥栄, 石川俊平, 池田栄二;編集)2011

    • Author(s)
      米澤 傑, 山田宗茂, 横山勢也, 北本 祥, 田畑和宏, 東美智代
    • Total Pages
      545
    • Publisher
      株式会社文光堂, 東京
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Book] Extrahepatic bile duct catrcinoma : Mucin 4, a poor prognostic factor

    • Author(s)
      Higashi, M., et.al.
    • Publisher
      Springer Publishing(印刷中)
    • Data Source
      KAKENHI-PROJECT-20014022
  • [Book] Extrahepatic bile duct catrcinoma : Mucin 4, a poor prognostic factor

    • Author(s)
      Higashi, M., et al.
    • Publisher
      Springer Publishing(印刷中)
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Book] Extrahepatic bile duct catrcinoma : Mucin4, a poor prognos ticfactor

    • Author(s)
      Higashi, M., et al.
    • Publisher
      Springer Publishing(印刷中)
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Book] Extrahepatic bile duct catrcinoma : Mucin 4, a poor prognostic factor

    • Author(s)
      Higashi, M., et al.
    • Publisher
      Springer Publishing(印刷中)
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Journal Article] Vascular endothelial growth factor inhibitors promote antitumor responses via tumor microenvironment immunosuppression in advanced colorectal cancer.2023

    • Author(s)
      Hamada Y, Tanoue K, Kita Y, Tanabe K, Hokonohara K, Wada M, Hozaka Y, Oi H, Nakayama C, Higashi M, Arigami T, Mori S, Ohtsuka T.
    • Journal Title

      Scand J Gastroenterol.

      Volume: - Issue: 9 Pages: 1-12

    • DOI

      10.1080/00365521.2023.2194011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08783, KAKENHI-PROJECT-22K16538, KAKENHI-PROJECT-21K06889
  • [Journal Article] Focal Type 2 Autoimmune Pancreatitis Mimicking Pancreatic Cancer: Treatment with Neoadjuvant Chemotherapy and Surgery2023

    • Author(s)
      Nobuhisa Maeda, Shiroh Tanoue , Yusuke Fujino , Makoto Hinokuchi, Shiho Arima, Fumisato Sasaki , Shinichi Hashimoto , Shuji Kanmura, Michiyo Higashi and Akio Ido
    • Journal Title

      Intern. Med.

      Volume: 62 Issue: 17 Pages: 2499-2505

    • DOI

      10.2169/internalmedicine.0224-22

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2023-09-01
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K06889
  • [Journal Article] Next-Generation Sequencing Analysis of Pancreatic Cancer Using Residual Liquid Cytology Specimens from Endoscopic Ultrasound?Guided Fine-Needle Biopsy: A Prospective Comparative Study with Tissue Specimens2023

    • Author(s)
      Iwaya Hiromichi、Tanimoto Akihide、Toyodome Koshiro、Kojima Issei、Hinokuchi Makoto、Tanoue Shiroh、Hashimoto Shinichi、Kawahira Machiko、Arima Shiho、Kanmura Shuji、Akahane Toshiaki、Higashi Michiyo、Suzuki Shinsuke、Ueno Shinichi、Ohtsuka Takao、Ido Akio
    • Journal Title

      Diagnostics

      Volume: 13 Issue: 6 Pages: 1078-1078

    • DOI

      10.3390/diagnostics13061078

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03753, KAKENHI-PROJECT-21K06889, KAKENHI-PROJECT-23K27675
  • [Journal Article] Are intratumoral microbiota involved in the progression of intraductal papillary mucinous neoplasms of the pancreas?2023

    • Author(s)
      Hozaka Yuto、Oi Hideyuki、Satake Souichi、Uchino Yoshinori、Goto Yuichi、Idichi Tetsuya、Tanoue Kiyonori、Yamasaki Yoichi、Kawasaki Yota、Mataki Yuko、Kurahara Hiroshi、Nakajo Akihiro、Higashi Michiyo、Tanimoto Akihide、Sugiura Tsuyoshi、Ohtsuka Takao
    • Journal Title

      Surgery

      Volume: 173 Issue: 2 Pages: 503-510

    • DOI

      10.1016/j.surg.2022.10.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K10224, KAKENHI-PROJECT-22K19567, KAKENHI-PROJECT-22K16514, KAKENHI-PROJECT-20H03753, KAKENHI-PROJECT-19K10361, KAKENHI-PROJECT-21K16453, KAKENHI-PROJECT-21K06889
  • [Journal Article] Gallbladder microbiota composition is associated with pancreaticobiliary and gallbladder cancer prognosis.2022

    • Author(s)
      Kirishima M, Yokoyama S, Matsuo K, Hamada T, Shimokawa M, Akahane T, Sugimoto T, Tsurumaru H, Ishibashi M, Mataki Y, Ootsuka T, Nomoto M, Hayashi C, Horiguchi A, Higashi M, Tanimoto A
    • Journal Title

      BMC Microbiol.

      Volume: 22 Issue: 1 Pages: 147-147

    • DOI

      10.1186/s12866-022-02557-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06889, KAKENHI-PROJECT-21K07222
  • [Journal Article] Sequential evaluation of MUC promoter methylation using next-generation sequencing-based custom-made panels in liquid-based cytology specimens of pancreatic cancer.2022

    • Author(s)
      Yokoyama S, Iwaya H, Akahane T, Hamada T, Higashi M, Hashimoto S, Tanoue S, Ohtsuka T, Ido A, Tanimoto A
    • Journal Title

      Diagn Cytopathol.

      Volume: 50 Issue: 11 Pages: 499-507

    • DOI

      10.1002/dc.25022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06889, KAKENHI-PROJECT-21K07222, KAKENHI-PROJECT-20H03753
  • [Journal Article] A deep learning model to detect pancreatic ductal adenocarcinoma on endoscopic ultrasound-guided fine-needle biopsy2021

    • Author(s)
      Yoshiki Naito, Masayuki Tsuneki , Noriyoshi Fukushima , Yutaka Koga , Michiyo Higashi , 他23名
    • Journal Title

      Sci Rep

      Volume: 19 Issue: 1 Pages: 8454-8454

    • DOI

      10.1038/s41598-021-87748-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07019, KAKENHI-PROJECT-21K06889
  • [Journal Article] Clinical Utility and Limitation of Diagnostic Ability for Different Degrees of Dysplasia of Intraductal Papillary Mucinous Neoplasms of the Pancreas Using 18F-Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography2021

    • Author(s)
      Hozaka Yuto、Kurahara Hiroshi、Oi Hideyuki、Idichi Tetsuya、Yamasaki Yoichi、Kawasaki Yota、Tanoue Kiyonori、Jinguji Megumi、Nakajo Masatoyo、Tani Atsushi、Nakajo Akihiro、Mataki Yuko、Fukukura Yoshihiko、Noguchi Hirotsugu、Higashi Michiyo、Yoshiura Takashi、Tanimoto Akihide、Ohtsuka Takao
    • Journal Title

      Cancers

      Volume: 13 Issue: 18 Pages: 4633-4633

    • DOI

      10.3390/cancers13184633

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21633, KAKENHI-PROJECT-20H03753, KAKENHI-PROJECT-21K16453
  • [Journal Article] Rare histological subtype of invasive micropapillary carcinoma in the ampulla of Vater: A case report.2021

    • Author(s)
      Noguchi H, Higashi M, Idichi T, Kurahara H, Mataki Y, Tasaki T, Kitazono I, Ohtsuka T, Tanomoto A.
    • Journal Title

      World J Clin Cases.

      Volume: 9 Issue: 11 Pages: 2671-9

    • DOI

      10.12998/wjcc.v9.i11.2671

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06889
  • [Journal Article] 【各施設での胆膵疾患に対する診療科横断的チーム医療】鹿児島大学病院での胆膵疾患に対するチーム医療.2021

    • Author(s)
      橋元 慎, 児島 一, 川平 真, 樋之口 真, 岩屋 博, 有馬 志, 田之上 史, 蔵原 弘, 又木 雄, 熊谷 雄, 伊藤 宗, 林 完, 福倉 良, 東 美, 大塚 隆, 井戸 章。
    • Journal Title

      胆と膵

      Volume: 5 Pages: 475-80

    • Data Source
      KAKENHI-PROJECT-21K06889
  • [Journal Article] Predicted Prognosis of Pancreatic Cancer Patients by Machine Learning.2020

    • Author(s)
      Seiya Yokoyama, Taiji Hamada, Michiyo Higashi, Kei Matsuo, Kousei Maemura, Hiroshi Kurahara, Michiko Horinouchi, Tsubasa Hiraki, Tomoyuki Sugimoto, Toshiaki Akahane, Suguru Yonezawa, Marko Kornmann, Surinder K Batra, Michael A Hollingsworth, Akihide Tanimoto
    • Journal Title

      Clinical cancer research

      Volume: - Issue: 10 Pages: 2411-2421

    • DOI

      10.1158/1078-0432.ccr-19-1247

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07326, KAKENHI-PROJECT-17K00054, KAKENHI-PROJECT-18K07019
  • [Journal Article] Lung recurrence and its therapeutic strategy in patients with pancreatic cancer2020

    • Author(s)
      Kurahara Hiroshi、Maemura Kosei、Mataki Yuko、Tanoue Kiyonori、Iino Satoshi、Kawasaki Yota、Idichi Tetsuya、Arigami Takaaki、Mori Shinichiro、Shinden Yoshiaki、Higashi Michiyo、Ueno Shinichi、Shinchi Hiroyuki、Natsugoe Shoji
    • Journal Title

      Pancreatology

      Volume: 20 Issue: 1 Pages: 89-94

    • DOI

      10.1016/j.pan.2019.11.015

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15219, KAKENHI-PROJECT-18K07019, KAKENHI-PROJECT-18K08626
  • [Journal Article] Comprehensive validation of liquid-based cytology specimens for next-generation sequencing in cancer genome analysis.2019

    • Author(s)
      Akahane T, Yamaguchi T, Kato Y, Yokoyama S, Hamada T, Nishida Y, Higashi M, Nishihara H, Suzuki S, Ueno S, Tanimoto A.
    • Journal Title

      PloS one.

      Volume: 14 Issue: 6 Pages: 0217724-0217724

    • DOI

      10.1371/journal.pone.0217724

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07019
  • [Journal Article] Extracellular volume fraction determined by equilibrium contrast-enhanced multidetector computed tomography as a prognostic factor in unresectable pancreatic adenocarcinoma treated with chemotherapy2019

    • Author(s)
      Fukukura, Y. Kumagae, Y. Higashi, R. Hakamada, H. Takumi, K. Maemura, K. Higashi, M. Kamimura, K. Nakajo, M. Yoshiura, T.
    • Journal Title

      Eur Radiol

      Volume: 29 Issue: 1 Pages: 353-361

    • DOI

      10.1007/s00330-018-5570-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07019
  • [Journal Article] CT and MRI features of undifferentiated carcinomas with osteoclast-like giant cells of the pancreas: a case series2019

    • Author(s)
      Fukukura, Y. Kumagae, Y. Hirahara, M. Hakamada, H. Nagano, H. Nakajo, M. Kamimura, K. Nakajo, M. Higashi, M. Yoshiura, T.
    • Journal Title

      Abdominal radiology

      Volume: 44 Issue: 4 Pages: 1246-1255

    • DOI

      10.1007/s00261-019-01958-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07019
  • [Journal Article] PCP4/PEP19 upregulates aromatase gene expression via CYP19A1 promoter I.1 in human breast cancer SK-BR-3 cells2018

    • Author(s)
      Honjo Kie、Hamada Taiji、Yoshimura Takuya、Yokoyama Seiya、Yamada Sohsuke、Tan Yan-Qin、Leung Lai K.、Nakamura Norifumi、Ohi Yasuyo、Higashi Michiyo、Tanimoto Akihide
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 51 Pages: 29619-29633

    • DOI

      10.18632/oncotarget.25651

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07018, KAKENHI-PROJECT-18K07019
  • [Journal Article] 集学的治療で完全奏効が得られた肝転移を伴うcStage IV膵体部癌の1例2018

    • Author(s)
      伊地知, 徹也 蔵原, 弘 前村, 公成 又木, 雄弘 川崎, 洋太 迫田, 雅彦 飯野, 聡 上野, 真一 新地, 洋之 東, 美智代 夏越, 祥次
    • Journal Title

      日本消化器外科学会雑誌

      Volume: 50 Pages: 897-904

    • NAID

      130006210157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08349
  • [Journal Article] TET1-mediated DNA hypomethylation regulates the expression of MUC4 in lung cancer2017

    • Author(s)
      Yokoyama, S. Higashi, M. Tsutsumida, H. Wakimoto, J. Hamada, T. Wiest, E. Matsuo, K. Kitazono, I. Goto, Y. Guo, X. Hamada, T. Yamada, S. Hiraki, T. Yonezawa, S. Batra, S. K. Hollingsworth, M. A. Tanimoto, A.
    • Journal Title

      Genes & cancer

      Volume: 8 Issue: 3-4 Pages: 517-527

    • DOI

      10.18632/genesandcancer.139

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08349, KAKENHI-PROJECT-15K11297, KAKENHI-PROJECT-15K21247
  • [Journal Article] Diagnostic efficacy of liquid-based cytology for solid pancreatic lesion samples obtained with endoscopic ultrasound-guided fine-needle aspiration: Propensity score-matched analysis2017

    • Author(s)
      Hashimoto, S. Taguchi, H. Higashi, M. Hatanaka, K. Fujita, T. Iwaya, H. Nakazawa, J. Arima, S. Iwashita, Y. Sasaki, F. Nasu, Y. Kanmura, S. Ido, A.
    • Journal Title

      Digestive endoscopy

      Volume: 29 Issue: 5 Pages: 608-616

    • DOI

      10.1111/den.12827

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08349
  • [Journal Article] Immunohistochemical expression of mucin antigens in gallbladder adenocarcinoma: MUC1-positive and MUC2-negative expression Is associated with vessel invasion and shortened survival2017

    • Author(s)
      Hiraki, T. Yamada, S. Higashi, M. Hatanaka, K. Yokoyama, S. Kitazono, I. Goto, Y. Kirishima, M. Batra, S. K. Yonezawa, S. Tanimoto, A.
    • Journal Title

      Histol Histopathol

      Volume: 32 Pages: 585-596

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08349
  • [Journal Article] Assessment of tumor characteristics based on glycoform analysis of membrane-tethered MUC12017

    • Author(s)
      Atsushi Matsuda, Michiyo Higashi, Tomomi Nakagawa, Seiya Yokoyama, Atsushi Kuno, Suguru Yonezawa, and Hisashi Narimatsu
    • Journal Title

      Laboratory Investigation

      Volume: 印刷中

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08349
  • [Journal Article] Assessment of tumor characteristics based on glycoform analysis of membrane-tethered MUC12017

    • Author(s)
      Matsuda, A. Higashi, M. Nakagawa, T. Yokoyama, S. Kuno, A. Yonezawa, S. Narimatsu, H.
    • Journal Title

      Lab Invest

      Volume: 97 Issue: 9 Pages: 1103-1113

    • DOI

      10.1038/labinvest.2017.53

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08349, KAKENHI-PROJECT-15K21247, KAKENHI-PROJECT-15K21667
  • [Journal Article] Aberrant methylation of MUC1 and MUC4 promoters are potential prognostic biomarkers for pancreatic ductal adenocarcinomas2016

    • Author(s)
      Yokoyama, S. Higashi, M. Kitamoto, S. Oeldorf, M. Knippschild, U. Kornmann, M. Maemura, K. Kurahara, H. Wiest, E. Hamada, T. Kitazono, I. Goto, Y. Tasaki, T. Hiraki, T. Hatanaka, K. Mataki, Y. Taguchi, H. Hashimoto, S. Batra, S. K. Tanimoto, A. Yonezawa, S. Hollingsworth, M. A.
    • Journal Title

      Oncotarget

      Volume: - Issue: 27 Pages: 42553-42565

    • DOI

      10.18632/oncotarget.9924

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08349, KAKENHI-PROJECT-15K21247, KAKENHI-PROJECT-15H05045
  • [Journal Article] Dexamethasone Suppression FDG PET/CT for Differentiating between True- and False-Positive Pulmonary and Mediastinal Lymph Node Metastases in Non-Small Cell Lung Cancer: A Pilot Study of FDG PET/CT after Oral Administration of Dexamethasone2016

    • Author(s)
      Nakajo, M. Nakajo, M. Nakayama, H. Jinguji, M. Nakabeppu, Y. Higashi, M. Nakamura, Y. Sato, M. Yoshiura, T.
    • Journal Title

      Radiology

      Volume: 279 Issue: 1 Pages: 246-253

    • DOI

      10.1148/radiol.2015150883

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08349
  • [Journal Article] Pancreatic hamartoma: a case report and literature review.2016

    • Author(s)
      Matsushita D, Kurahara H, Mataki Y, Maemura K, Higashi M, Iino S, et al.
    • Journal Title

      BMC gastroenterology.

      Volume: 16 Issue: 1 Pages: 419-422

    • DOI

      10.1186/s12876-016-0419-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08349
  • [Journal Article] Pancreatic neuroendocrine tumors: Correlation between the contrast-enhanced computed tomography features and the pathological tumor grade.2015

    • Author(s)
      Takumi K, Fukukura Y, Higashi M, Ideue J, Umanodan T, Hakamada H, et al.
    • Journal Title

      Eur J Radiol.

      Volume: 84 Issue: 8 Pages: 1436-43

    • DOI

      10.1016/j.ejrad.2015.05.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08349
  • [Journal Article] Mucin expression in endoscopic ultrasound-guided fine-needle aspiration specimens is a useful prognostic factor in pancreatic ductal adenocarcinoma2015

    • Author(s)
      Michiyo Higashi, Seiya Yokoyama, Takafumi Yamamoto, Yuko Goto, Ikumi Kitazono, Tsubasa Hiraki, Hiroki Taguchi, Shinichi Hashimoto, Yoshihiko Fukukura, Chihaya Koriyama, Yuko Mataki, Kosei Maemura, Hiroyuki Shinchi, Maneesh Jain, Surinder K. Batra, Suguru Yonezawa
    • Journal Title

      Pancreas

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26290048
  • [Journal Article] Computed tomography and magnetic resonance imaging features of lipid-rich neuroendocrine tumors of the pancreas2015

    • Author(s)
      Fukukura Y, Shindo T, Higashi M, Takumi K, Umanodan T, Yoneyama T, et al.
    • Journal Title

      World journal of gastroenterology : WJG

      Volume: 21 Issue: 34 Pages: 10008-17

    • DOI

      10.3748/wjg.v21.i34.10008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08349
  • [Journal Article] Combination of MUC1 and MUC4 expression predicts clinical outcome in patients with oral squamous cell carcinoma2015

    • Author(s)
      Kamikawa, Y. Kanmura, Y. Hamada, T. Yamada, N. Macha, M. A. Batra, S. K. Higashi, M. Yonezawa, S. Sugihara, K.
    • Journal Title

      Int J Clin Oncol

      Volume: 20 Issue: 2 Pages: 298-307

    • DOI

      10.1007/s10147-014-0710-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590447
  • [Journal Article] 新規DNAメチル化解析法の開発と応用2015

    • Author(s)
      横山勢也、北本祥、山田宗茂、東美智代、米澤傑
    • Journal Title

      化学工業

      Volume: 66 Pages: 28-33

    • Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590447
  • [Journal Article] Mucin expression in endoscopic ultrasound-guided fine-needle aspiration specimens is a useful prognostic factor in pancreatic ductal adenocarcinoma.2015

    • Author(s)
      Higashi M, Yokoyama S, Yamamoto T, Goto Y, Kitazono I, Hiraki T, et al.
    • Journal Title

      Pancreas

      Volume: 44 Issue: 5 Pages: 728-34

    • DOI

      10.1097/mpa.0000000000000362

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08349, KAKENHI-PROJECT-26462068, KAKENHI-PROJECT-15K21247
  • [Journal Article] 新規DNAメチル化解析法の開発と応用2015

    • Author(s)
      横山 勢也、北本 祥、山田 宗茂、東 美智代、米澤 傑
    • Journal Title

      化学工業

      Volume: 66 Pages: 28-33

    • Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26290048
  • [Journal Article] Contrast-enhanced CT and diffusion-weighted MR imaging: Performance as a prognostic factor in patients with pancreatic ductal adenocarcinoma2014

    • Author(s)
      Fukukura, Y. Takumi, K. Higashi, M. Shinchi, H. Kamimura, K. Yoneyama, T. Tateyama, A.
    • Journal Title

      Eur J Radiol

      Volume: 83 Issue: 4 Pages: 612-619

    • DOI

      10.1016/j.ejrad.2013.12.016

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-26462068
  • [Journal Article] Pathobiological implications of mucin (MUC) expression in the outcome of small bowel cancer2014

    • Author(s)
      Shibahara H, Higashi M, Koriyama C, Yokoyama S, Kitazono I, Yasuhiro K, Narita M, Kuze S, Takanori K, Mita S, Arai T, Kato T, Yuasa N, Yamaguchi R, Kubota H, Suzuki H, Baba S, Rousseau K, Batra S K, Yonezawa S
    • Journal Title

      PLoS ONE

      Volume: 9(4) Issue: 4 Pages: e86111-e86111

    • DOI

      10.1371/journal.pone.0086111

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
  • [Journal Article] A comprehensive expression analysis of mucins in appendiceal carcinoma in a multicenter study: MUC3 is a novel prognostic factor2014

    • Author(s)
      Shibahara, H. Higashi, M. Yokoyama, S. Rousseau, K. Kitazono, I. Osako, M. Shirahama, H. Tashiro, Y. Kurumiya, Y. Narita, M. Kuze, S. Hasagawa, H. et al.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 12 Pages: e115613-e115613

    • DOI

      10.1371/journal.pone.0115613

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-26290048
  • [Journal Article] Diagnosis of pancreatic neoplasms using a novel method of DNA methylation analysis of mucin expression in pancreatic juice2014

    • Author(s)
      Yokoyama S, Kitamoto S, Higashi M, Goto Y, Hara T, Ikebe D, Yamaguchi T, Arisaka Y, Niihara, Nishimata H, Tanaka S, Takaori K, Batra S K, Yonezawa S
    • Journal Title

      PLoS ONE

      Volume: 9(4) Issue: 4 Pages: e93760-e93760

    • DOI

      10.1371/journal.pone.0093760

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
  • [Journal Article] 特集 胆膵病理II:胆膵共通のトピックス【胆膵共通疾患とトピックス】膵胆道腫瘍におけるMUC発現.2013

    • Author(s)
      米澤 傑、東美智代、横山勢也、後藤優子、北島信一
    • Journal Title

      病理と臨床

      Volume: 31 Pages: 399-408

    • Data Source
      KAKENHI-PROJECT-23390085
  • [Journal Article] 胆道系腫瘍における粘液産生の組織学的側面2013

    • Author(s)
      東 美智代、 柴原 弘明、 後藤 優子、 平木 翼、 横山 勢也、 米澤 傑
    • Journal Title

      胆と膵

      Volume: 34 Pages: 353-358

    • Data Source
      KAKENHI-PROJECT-24590447
  • [Journal Article] The etiologic role of human papillomavirus in penile cancers: a study in Vietnam2013

    • Author(s)
      Do, H. T. Koriyama, C. Khan, N. A. Higashi, M. Kato, T. Le, N. T. Matsushita, S. Kanekura, T. Akiba, S.
    • Journal Title

      Br J Cancer

      Volume: 108 Issue: 1 Pages: 229-233

    • DOI

      10.1038/bjc.2012.583

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-25461702
  • [Journal Article] 胆膵共通疾患とトピックス 膵胆道腫瘍におけるMUC発現2013

    • Author(s)
      米澤 傑、 東 美智代、 横山 勢也、 後藤 優子、北島 信一
    • Journal Title

      病理と臨床

      Volume: 31 Pages: 399-408

    • Data Source
      KAKENHI-PROJECT-24590447
  • [Journal Article] 特集 胆膵病理II:胆膵共通のトピックス【胆膵共通疾患とトピックス】膵胆道腫瘍におけるMUC発現2013

    • Author(s)
      米澤 傑、東美智代、横山勢也、後藤優子、  北島信一
    • Journal Title

      病理と臨床

      Volume: 31 Pages: 399-408

    • Data Source
      KAKENHI-PROJECT-23390085
  • [Journal Article] MUC4 and MUC1 Expression in Adenocarcinoma of the Stomach Correlates with Vessel Invasion and Lymph Node Metastasis : An Immunohisto chemical Study of Early Gastric Cancer.2013

    • Author(s)
      Yukihiro Tamura, Michiyo Higashi, Sho Kitamoto, Seiya Yokoyama, Masahiko Osako, Michiko Horinouchi, Takeshi Shimizu, Mineo Tabata, Surinder K. Batra, Masamichi Goto, Suguru Yonezawa
    • Journal Title

      PLoS ONE

      Volume: (in press) Issue: 11 Pages: e49251-e49251

    • DOI

      10.1371/journal.pone.0049251

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
  • [Journal Article] Expression of MUC4 mucin is observed mainly in the intestinal-type of intraductal papillary mucinous neoplasm of the pancreas2013

    • Author(s)
      Kitazono I, Higashi M, Kitamoto S, Yokoyama S, Horinouchi M, Osako M, Shimizu T, Tabata M, Batra S K, Goto M, Yonezawa S
    • Journal Title

      Pancreas

      Volume: 42(7) Issue: 7 Pages: 1120-1128

    • DOI

      10.1097/mpa.0b013e3182965915

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
  • [Journal Article] MUC1 enhances hypoxia-driven angiogenesis through the regulation of multiple proangiogenic factors2013

    • Author(s)
      Sho Kitamoto, Soiya Yokoyama, Michiyo Higashi, Norishlge Yamada, Sonshin Takao, Suguru Yonezawa
    • Journal Title

      Oncogene

      Volume: 32(39) Issue: 39 Pages: 4614-4621

    • DOI

      10.1038/onc.2012.478

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
  • [Journal Article] 特集:粘液産生性胆道系腫瘍の再出発-エビデンスとしての画像と病理 「2.胆道系腫瘍における粘液産生の組織学的側面」2013

    • Author(s)
      東美智代、柴原弘明、後藤優子、平木 翼、   横山勢也、米澤 傑
    • Journal Title

      胆と膵

      Volume: 34

    • Data Source
      KAKENHI-PROJECT-23390085
  • [Journal Article] 特集:粘液産生性胆道系腫瘍の再出発-エビデンスとしての画像と病理 「胆道系腫瘍における粘液産生の組織学的側面」.2013

    • Author(s)
      東美智代、柴原弘明、後藤優子、平木 翼、横山勢也、米澤 傑
    • Journal Title

      胆と膵

      Volume: 34 Pages: 353-358

    • Data Source
      KAKENHI-PROJECT-23390085
  • [Journal Article] 術前化学(放射線)療法を行った切除可能および境界膵癌の検討2013

    • Author(s)
      又木 雄弘、新地 洋之、前村 公成、蔵原 弘、川崎 洋太、出先 亮介、上野 真一、迫田 雅彦、 飯野 聡 、東 美智代、 高尾 尊身、夏越 祥次
    • Journal Title

      癌と化学療法

      Volume: 40 Pages: 1637-1640

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590447
  • [Journal Article] The application of Methylation specific electrophoresis(MSE) to DNA methylation analysis of the 5' CpG island of mucin in cancer cells2012

    • Author(s)
      Yokoyama S, Kitamoto S, Yamada N, Houjou I, Sugai T, Nakamura S, Arisaka Y, Takaori K, Higashi M, Yonezawa S.
    • Journal Title

      BMC Cancer

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] The application of Methylation specific electrophoresis (MSE) to DNA methylation analysis of the 5' CpG island of mucin in cancer cells2012

    • Author(s)
      Seiya Yokoyama
    • Journal Title

      BMC Cancer

      Volume: 12(In press) Issue: 1 Pages: 67-67

    • DOI

      10.1186/1471-2407-12-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-21590399, KAKENHI-PROJECT-22590317, KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
  • [Journal Article] Pathobiological Implications of MUC16/CA125 Expression in Intrahepatic Cholangiocarcinoma-Mass Forming Type2012

    • Author(s)
      Higashi M, Yamada N, Yokoyama S, Kitamoto S, Tabata K, Koriyama C, Batra SK, Yonezawa S.
    • Journal Title

      Pathobiology

      Volume: 79巻 Pages: 101-106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] Pathobiological implications of expression of MUC16/CA125 in intrahepatic cholangiocarcinoma-mass formina type2012

    • Author(s)
      Michiyo Higashi
    • Journal Title

      Pathobiology

      Volume: 79 Issue: 2 Pages: 101-106

    • DOI

      10.1159/000335164

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-21590399, KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
  • [Journal Article] Expression of MUC17 Is Regulated by HIF1α-mediated Hypoxic Responses and Requires a Methylation-free Hypoxia Responsible Element in Pancreatic Cancer.2012

    • Author(s)
      Sho Kitamoto, Seiya Yokoyama, Michiyo Higashi, Norishige Yamada, Shyuichiro Matsubara, Sonshin Takao, Surinder K. Batra, Suguru Yonezawa
    • Journal Title

      PLoS ONE

      Volume: 7(9) Issue: 9 Pages: e44108-e44108

    • DOI

      10.1371/journal.pone.0044108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24701008
  • [Journal Article] A novel anti-MUC1 antibody against the MUC1 cytoplasmic tail domain : use in sensitive identification of poorly differentiated cells in adenocarcinoma of the stomach2012

    • Author(s)
      Suguru Yonezawa
    • Journal Title

      Gastric Cancer

      Volume: (In press) Issue: 4 Pages: 370-381

    • DOI

      10.1007/s10120-011-0125-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-21590399, KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
  • [Journal Article] 癌におけるムチンの臨床病理学的意義および診断への応用  -難治性膵胆管癌の早期診断に向けて-2012

    • Author(s)
      米澤 傑、東美智代、横山勢也、北本 祥、   山田宗茂
    • Journal Title

      MEDICAL TECNOLOGY

      Volume: 40 Pages: 419-425

    • Data Source
      KAKENHI-PROJECT-23390085
  • [Journal Article] 胆管内乳頭状腫瘍(IPNB):粘液,MUC発現からのアプローチ2012

    • Author(s)
      東美智代、横山勢也、北本 祥、米澤 傑
    • Journal Title

      肝胆膵

      Volume: 65 Pages: 487-494

    • Data Source
      KAKENHI-PROJECT-23390085
  • [Journal Article] 肝内胆管、胆道、膵共通の視点に立った腫瘍発生腫瘍発生と化生・粘液形質2011

    • Author(s)
      東美智代, 他
    • Journal Title

      肝・胆・膵

      Volume: 62 Pages: 29-38

    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] 腫瘍発生と化生・粘液形質2011

    • Author(s)
      東美智代, 他
    • Journal Title

      肝胆膵

      Volume: 62 Pages: 29-38

    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] Epigenetic regulation of mucin genes in human cancers2011

    • Author(s)
      Norishige Yamada
    • Journal Title

      Clinical Epigenetics

      Volume: 2 Issue: 2 Pages: 85-96

    • DOI

      10.1007/s13148-011-0037-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-21590399, KAKENHI-PROJECT-23390085
  • [Journal Article] 腫瘍発生と化生・粘液形質2011

    • Author(s)
      東美智代, 他
    • Journal Title

      肝胆膵

      Volume: 62 Pages: 29-38

    • Data Source
      KAKENHI-PROJECT-20590345
  • [Journal Article] Uterine cervical carcinomas associated with lobular endocervical glandular hyperplasia2011

    • Author(s)
      Tsuji T, Togami S, Nomoto M, Higashi M, Fukukura Y, Kamio M, Yonezawa S, Douch T.
    • Journal Title

      Histopathology

      Volume: 59巻 Pages: 55-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] DNA methylation and histone H3-K9 modifications contribute to MUC17 expression2011

    • Author(s)
      Kitamoto S, Yamada N, Yokoyama S, Houjou I, Higashi M, Goto M, Batra SK, Yonezawa S.
    • Journal Title

      Glycobiology

      Volume: 21巻 Pages: 247-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] Mucins in human neoplasms : Clinical pathology, gene expression and diagnostic application2011

    • Author(s)
      Suguru Yonezawa
    • Journal Title

      Pathology International

      Volume: 61 Issue: 12 Pages: 697-716

    • DOI

      10.1111/j.1440-1827.2011.02734.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-21590399, KAKENHI-PROJECT-23390085
  • [Journal Article] DNA methylation and histone H3-K9 modifications contribute to MUC17 expression.2011

    • Author(s)
      Kitamoto S, Yamada N, Yokoyama S, Houjou I, Higashi M, Goto M, Batra S K, Yonezawa S
    • Journal Title

      Glycobiology 21(2)

      Pages: 247-256

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Journal Article] Expression of MUC5AC, an early marker of pancreatobiliary cancer, is regulated by DNA methylation in the distal promoter region in cancer cells2010

    • Author(s)
      Yamada N, Nishida Y, Yokoyama S, Tsutsumida H, Houjou I, Kitamoto S, Goto M, Higashi M, and Yonezawa S.
    • Journal Title

      J Hepatobiliary Pancreat Sci

      Volume: 17巻 Pages: 844-54

    • NAID

      10027664155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] Expression of mucin antigens(MUC1 and MUC16) as a prognostic factor for mucinous adenocarcinoma of the uterine cervix2010

    • Author(s)
      Togami S, Nomoto M, Higashi M, Goto M, Yonezawa S, Tsuji T, Batra SK, Douchi T.
    • Journal Title

      J Obstet Gynaecol Res

      Volume: 36巻 Pages: 588-97

    • NAID

      10031121662

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] Immunohistochemical study of mucin expression in periampullary adenomyoma2010

    • Author(s)
      Higashi M, Goto M, Saitou M, Shimizu T, Rousseau K, Batra SK, and Yonezawa S.
    • Journal Title

      J Hepatobiliary Pancreat Sci

      Volume: 17巻 Pages: 275-83

    • NAID

      10027422658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] Immunohistochemical study of mucin expression in periampullary adenomyoma2010

    • Author(s)
      Higashi, M., et al.
    • Journal Title

      Journal of Hepato-Biliary-Pancreatic Sciences

      Volume: 17 Pages: 275-283

    • NAID

      10027422658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Journal Article] Significance of mucin expression in pancreatobiliary neoplasms2010

    • Author(s)
      Yonezawa S, Higashi M, Yamada N, Yokoyama S, Goto M.
    • Journal Title

      J Hepatobiliary Pancreat Sci

      Volume: 17巻 Pages: 108-24

    • NAID

      10027662473

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] Expression of MUC5AC, an early marker of pancreatobiliary cancer, is regulated by DNA methylation in the distal promoter region in cancer cells.2010

    • Author(s)
      Yamada N, Nishida Y, Yokoyama S, Tsutsumida H, Houjou I, Kitamoto S, Goto M, Higashi M, Yonezawa S
    • Journal Title

      J Hepatobiliary Pancreat Sci 17(6)

      Pages: 844-854

    • NAID

      10027664155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Journal Article] Immunohistochemical study of mucin expression in periampullary adenomyoma2010

    • Author(s)
      Higashi, M., et al.
    • Journal Title

      Journal of Hepato-Biliary-Pancreatic Sciences

      Volume: 17 Pages: 275-283

    • NAID

      10027422658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] Significance of mucin expression in pancreatobiliary neoplasms.2010

    • Author(s)
      Yonezawa S, Higashi M, Yamada N, Yokoyama S, Goto M
    • Journal Title

      J Hepatobiliary Pancreat Sci 17(2)

      Pages: 108-124

    • NAID

      10027662473

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Journal Article] Promoter hypomethylation contributes to the expression of MUC3A in cancer cells2010

    • Author(s)
      Kitamoto S, Yamada N, Yokoyama S, Houjou I, Higashi M, Yonezawa S.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 397巻 Pages: 333-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] Promoter hypomethylation contributes to the expression of MUC3A in cancer cells.2010

    • Author(s)
      Kitamoto S, Yamada N, Yokoyama S, Houjou I, Higashi M, Yonezawa S
    • Journal Title

      Biochem Biophys Res Commun, 397(2)

      Pages: 333-339

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Journal Article] 膵・胆道系腫瘍のトピックス-粘液産生性腫瘍を中心に- 粘液形質から考える膵・胆道粘液産生性腫瘍2009

    • Author(s)
      東美智代, 他
    • Journal Title

      病理と臨床 27(6)

      Pages: 531-538

    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] 膵・胆道系腫瘍のトピックス-粘液産生性腫瘍を中心に-粘液形質から考える膵・胆道粘液産生性腫瘍2009

    • Author(s)
      東美智代, 他
    • Journal Title

      病理と臨床 27

      Pages: 531-538

    • Data Source
      KAKENHI-PROJECT-20014022
  • [Journal Article] Promoter CpG methylation in cancer cells contributes to the regulation of MUC42009

    • Author(s)
      Yamada N, Nishida Y, Tsutsumida H, Goto M, Higashi M, Nomoto M, Yonezawa S.
    • Journal Title

      Br J Cancer

      Volume: 100巻 Pages: 344-51

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] Promoter CpG methylation in cancer cells contributes to regulation of MUC4.2009

    • Author(s)
      Yamada N, Nishida Y, Tsutsumida H, Goto M, Higashi M, Nomoto M, Yonezawa S
    • Journal Title

      Br J Cancer 100(2)

      Pages: 344-351

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Journal Article] 膵・胆道系腫瘍のトピックス-粘液産生性腫瘍を中心に-粘液形質から考える膵・胆道粘液産生性腫瘍2009

    • Author(s)
      東美智代, 他
    • Journal Title

      病理と臨床 27

      Pages: 531-538

    • Data Source
      KAKENHI-PROJECT-20590345
  • [Journal Article] MUC1 expression is regulated by DNA methylation and histone H3 lysine 9 modification in cancer cells.2008

    • Author(s)
      Yamada N, Nishida Y, Tsutsumida H, Hamada T, Goto M, Higashi M, Nomoto M, Yonezawa S
    • Journal Title

      Cancer Res 68(8)

      Pages: 2708-2716

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Journal Article] Expression profiles of MUC1, MUC2 and MUC4 mucins in human neoplasms and their relationship with biological behavior.2008

    • Author(s)
      Yonezawa S, Goto M, Yamada N, Higashi M, Nomoto M
    • Journal Title

      Proteomics 8(16)

      Pages: 3329-3341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Journal Article] 特集 粘液産生胆管腫瘍におけるムチン蛋白発現2007

    • Author(s)
      東美智代、, 他
    • Journal Title

      消化器画像 9-3

      Pages: 255-259

    • Data Source
      KAKENHI-PROJECT-18014024
  • [Journal Article] 胆管,膵管の粘液特性と化生2006

    • Author(s)
      東美智代, 他
    • Journal Title

      肝胆膵 52・2

      Pages: 175-184

    • Data Source
      KAKENHI-PROJECT-18014024
  • [Journal Article] Immunohistochemical study of mucin expression in periampullary adenomyoma

    • Author(s)
      東美智代, et al.
    • Journal Title

      Journal of Hepato-Biliary-Pancreatic Sciences (印刷中)

    • NAID

      10027422658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Journal Article] Immunohistochemical study of mucin expression in periampullary adenomyoma

    • Author(s)
      東美智代, et al.
    • Journal Title

      J Hepatobiliary Pancreat Surg. (印刷中)

    • NAID

      10027422658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Journal Article] Immunohistochemical study of mucin expression in periampullary adenomyoma

    • Author(s)
      Higashi, M., et al.
    • Journal Title

      Journal of Hepato-Biliary-Pancreatic Sciences (印刷中)

    • NAID

      10027422658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20014022
  • [Patent] 癌の判定装置、癌の情報取得方法及びプログラム2022

    • Inventor(s)
      横山勢也、東美智代、谷本昭英
    • Industrial Property Rights Holder
      横山勢也、東美智代、谷本昭英
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-21K06889
  • [Presentation] DNAメチル化解析による胆管癌術後予後予測手法の構築2023

    • Author(s)
      横山勢也、東美智代、谷本昭英
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-21K06889
  • [Presentation] 局所内進展にとどまる胆嚢癌におけるムチン発現の検討2022

    • Author(s)
      能美 昌子, 東 美智代, 横山 勢也, 谷本 昭英, 瀧口 翔也, 薮田 愛, 利光 鏡太郎, 井戸 弘毅
    • Organizer
      日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-21K06889
  • [Presentation] DNAメチル化解析による胆管癌術後予後予測手法の構築2022

    • Author(s)
      横山 勢也, 霧島 茉莉, 東 美智代
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-21K06889
  • [Presentation] 膵胆管系癌と胆嚢中微生物叢との関連2021

    • Author(s)
      横山勢也、霧島茉莉、東美智代
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-21K06889
  • [Presentation] WHO 2019の変更点 IPNBの病理所見2021

    • Author(s)
      東美智代
    • Organizer
      断層映像研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K06889
  • [Presentation] DNAメチル化解析結果を用いた計算機科学による膵癌予後予測2021

    • Author(s)
      横山勢也、東美智代、谷本昭英
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K07019
  • [Presentation] 膵神経内分泌腫瘍の集学的治療 当院における遠隔転移を有するPanNENに対する集学的治療の現状について2021

    • Author(s)
      児島 一成, 岩屋 博道, 豊留 孝史郎, 川平 真知子 , 樋之口 真, 有馬 志穂 , 田ノ上 史郎, 橋元 慎一, 東 美智代, 大塚 隆生 , 井戸 章雄
    • Organizer
      日本膵臓学会
    • Data Source
      KAKENHI-PROJECT-21K06889
  • [Presentation] 胆道・膵臓腫瘍の遺伝子異常と病理診断 胆道・膵腫瘍の早期診断とバイオマーカー2020

    • Author(s)
      東 美智代, 横山 勢也, 平木 翼, 北薗 育美, 霧島 茉莉, 田中 貴子, 濱田 一正, 堀之内 道子, 米澤 傑, 谷本 昭英
    • Organizer
      日本病理学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07019
  • [Presentation] DNAメチル化解析結果を用いた計算機科学による膵癌予後予測2019

    • Author(s)
      横山勢也,東美智代,谷本昭英
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07326
  • [Presentation] 胆管癌におけるDNAメチル化解析2019

    • Author(s)
      横山勢也,東美智代,谷本昭英
    • Organizer
      第108回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-18K07326
  • [Presentation] DNAメチル化解析結果を用いた計算機科学による膵癌予後予測2019

    • Author(s)
      横山勢也,東美智代,谷本昭英
    • Organizer
      第4回黒潮カンファレンス
    • Data Source
      KAKENHI-PROJECT-18K07326
  • [Presentation] Predicted Prognosis of Pancreatic Cancer Patients by Machine Learning.2019

    • Author(s)
      横山勢也 東 美智代, 谷本 昭英
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K07019
  • [Presentation] MUC1およびMUC4遺伝子のメチル化解析による膵癌摘出術後の予後評価2018

    • Author(s)
      横山勢也,東美智代,谷本昭英
    • Organizer
      日本病理学会
    • Data Source
      KAKENHI-PROJECT-18K07326
  • [Presentation] MUC1およびMUC4遺伝子のメチル化解析による膵癌摘出術後の予後評価2018

    • Author(s)
      横山 勢也, 東 美智代, 谷本 昭英
    • Organizer
      日本病理学会
    • Data Source
      KAKENHI-PROJECT-18K07019
  • [Presentation] PDAC摘出術後におけるムチン遺伝子のメチル化解析を用いた予後予測法の構築2018

    • Author(s)
      横山 勢也, 東 美智代, 谷本 昭英
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K07019
  • [Presentation] PDAC摘出術後におけるムチン遺伝子のメチル化解析を用いた予後予測法の構築2018

    • Author(s)
      横山勢也,東美智代,谷本昭英
    • Organizer
      日本癌学会学
    • Data Source
      KAKENHI-PROJECT-18K07326
  • [Presentation] 粘膜類表皮癌においてMUC4とMUC6の発現低下から生存期間の短縮が予想される2017

    • Author(s)
      本庄, 希江 山口, 壮亮 平木, 翼 東, 美智代 吉村, 卓也 中村, 典史 野元, 三治 野口, 紘嗣 米澤, 傑 谷本, 昭英
    • Organizer
      日本病理学会
    • Data Source
      KAKENHI-PROJECT-15K08349
  • [Presentation] Analysis of Mucin expression and DNA methylation in serous adenoma of the pancreas2016

    • Author(s)
      Michiyo Higashi, Seiya Yokoyama, Tsubasa Hiraki , Ikumi Kitazono, Yuko Goto,Tasaki Takashi, Mari Kirishima, Kazuhito Hatanaka, and Akihide Tanimoto
    • Organizer
      日本病理学会第105回総会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K08349
  • [Presentation] Chemoradiation therapy for pancreatic adenocarcinoma patients: correlation between semiquantitative contrast-enhanced CT and overall survival2016

    • Author(s)
      Higashi R, Fukukura Y, Nakamura F, Ito S, Ueyama T, Kumagae Y, Yoshiura T
    • Organizer
      第75回 日本放射線学会総会
    • Place of Presentation
      パシフィコ横浜 神奈川県横浜市
    • Year and Date
      2016-04-14
    • Data Source
      KAKENHI-PROJECT-15K09931
  • [Presentation] Chemoradiation therapy for pancreatic adenocarcinoma patients: correlation between semiquantitative contrast-enhanced CT and overall survival2016

    • Author(s)
      Higashi R, Fukukura Y, Nakamura F, Ito S, Ueyama T, Kumagae Y, Yoshiura T.
    • Organizer
      第75回 日本放射線学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-04-14
    • Data Source
      KAKENHI-PROJECT-15K09931
  • [Presentation] 浸潤性膵管癌におけるEUS-FNAでのムチン発現2015

    • Author(s)
      東美智代、後藤優子、米澤傑
    • Organizer
      肝胆膵外科学会
    • Place of Presentation
      ホテルグランパシフィックLE DAIBA (東京都千代田区)
    • Year and Date
      2015-06-11
    • Data Source
      KAKENHI-PROJECT-15K08349
  • [Presentation] ムチン発現からみたIPMNの悪性度2015

    • Author(s)
      東美智代、横山勢也、北薗育美、後藤優子、田崎貴嗣、平木翼、畑中一仁、蔵原弘、又木雄弘、前村公成、新地洋之、谷本昭英、米澤傑、夏越祥次
    • Organizer
      外科病理学会
    • Place of Presentation
      ホテルアパローム紀ノ国(和歌山県和歌山市)
    • Year and Date
      2015-11-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K08349
  • [Presentation] 膵漿液性腫瘍の病理2015

    • Author(s)
      東美智代
    • Organizer
      日本病理学会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-04-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K08349
  • [Presentation] TET1 was important factor for DNA demethylation to regulate the expression of MUC1 and MUC4 in lung cancer.2014

    • Author(s)
      Seiya Yokoyama, Sho Kitamoto, Hideaki Tsutsumida, Joji Wakimoto, Michiyo Higashi, Suguru Yonezawa
    • Organizer
      23rd Biennial Congress of the European Association for Cancer Research
    • Place of Presentation
      International Congress Center Munich (Munchen, Germany)
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] Application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic, biliary, and pulmonary neoplasms2013

    • Author(s)
      Suguru Yonezawa, Seiya Yokoyama, Sho Kitamoto, Michiyo Higashi
    • Organizer
      MUCINS IN HEALTH AND DISEASE (12th International Workshop on Carcinoma-associated Mucins)
    • Place of Presentation
      Robinson College (Cambridge, UK)
    • Data Source
      KAKENHI-PROJECT-24590447
  • [Presentation] Examination of mucin expression including a novel DNA methylation analysis method (MSE): Its application for diagnosis of human pancreatic neoplasms.2013

    • Author(s)
      Yonezawa S, Yokoyama S, Goto Y, Higashi M
    • Organizer
      19th International Charles Heidelberger Symposium on Cancer Research
    • Place of Presentation
      William Willis Hall (Kagoshima, Japan)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] 膵癌におけるMUC1遺伝子のメチル化ステータスとmRNA発現解析2013

    • Author(s)
      横山勢也、 北本 祥、堤田英明、脇本譲二、東美智代、米澤 傑
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      ロイトン札幌 (北海道)
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] Mucin expression in pancreatic ductal adenocarcinoma: Immunohistochemical examination in EUS-FNAB specimens2013

    • Author(s)
      Michiyo Higashi, Yuko Goto, Suguru Yonezawa
    • Organizer
      25th European Congress of Pathology
    • Place of Presentation
      Centro de Congressos de Lisboa (Lisbon, Portugal)
    • Data Source
      KAKENHI-PROJECT-24590447
  • [Presentation] Application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic, biliary and pulmonary neoplasms, MUCINS IN HEALTH AND DISEASE2013

    • Author(s)
      Yonezawa S, Yokoyama S, Kitamoto S, Higashi M
    • Organizer
      12th International Workshop on Carcinoma-associated Mucins
    • Place of Presentation
      Robinson College (Cambridge, UK)
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] Diagnosis of pancreatic neoplasms by application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic juice2013

    • Author(s)
      Suguru Yonezawa, Seiya Yokoyama, Michiyo Higashi, Yuko Goto, Shinichi Kitajima
    • Organizer
      Worldwide Innovate Networking in personalized cancer medicine
    • Place of Presentation
      Le Palais des Congred (Paris, France)
    • Data Source
      KAKENHI-PROJECT-24590447
  • [Presentation] Diagnosis of pancreatic neoplasms by application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic juices.2013

    • Author(s)
      Yonezawa Suguru,Yokoyama Seiya, Higashi Michiyo, Goto Yuko, Kitajima Shinichi
    • Organizer
      Worldwide Innovative Networking in personalized cancer medicine
    • Place of Presentation
      Le Palais des Congres (Paris, France)
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] 膵癌におけるMUC1遺伝子のメチル化ステータスとmRNA発現解析2013

    • Author(s)
      横山勢也、北本祥、堤田英明、脇本譲二、東美智代、米澤傑
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Data Source
      KAKENHI-PROJECT-24590447
  • [Presentation] 浸潤性膵管癌におけるEUS-FNABでのムチン発現2013

    • Author(s)
      東美智代、横山勢也、後藤優子、平木翼、後藤正道、米澤傑
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Data Source
      KAKENHI-PROJECT-24590447
  • [Presentation] Mucin expression in pancreatic ductal adenocarcinoma: Immunohistochemical examination in EUS-FNAB specimens.2013

    • Author(s)
      Michiyo Higashi, Yuko Goto, Suguru Yonezawa
    • Organizer
      25th European Congress of Pathology
    • Place of Presentation
      Centro de Congressos de Lisboa (Lisbon, Portugal)
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] 新しい高感度DNAメチル化高感度検出法(MSE法)を用いた膵液中のムチン発現遺伝子解析による膵腫瘍の診断2013

    • Author(s)
      米澤 傑、東美智代、横山勢也、後藤優子、平木 翼、北島信一、原 太郎、有坂好史、新原 亨、高折恭一
    • Organizer
      第30回日本胆膵病態・生理研究会
    • Place of Presentation
      ウエスティンホテル仙台 (宮城)
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] Application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic, biliary and pulmonary neoplasms2013

    • Author(s)
      Suguru Yonezawa,Seiya Yokoyama, Sho Kitamoto, Michiyo Higashi
    • Organizer
      MUCINS IN HEALTH AND DISEASE (12th International Workshop on Carcinoma-associated Mucins)
    • Place of Presentation
      Robionson College (Cambridge, UK)
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] 膵癌におけるMUC17の低酸素応答メカニズムの解明2012

    • Author(s)
      北本 祥、横山勢也、東 美智代、米澤 傑
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル (東京)
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] 新規高感度DNAメチル化解析法(MSE法)による膵IPMN亜型の早期診断へ向けた応用2012

    • Author(s)
      横山勢也、北本 祥、東美智代、米澤 傑
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル (東京)
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] The application of new DNA methylation analysis, designated methylation specific electrophoresis (MSE) for pancreatic juice analysis.2012

    • Author(s)
      Yokoyama S, kitamoto S, Hara T, Arisaka Y, Takaori K, Yamamoto T, Niihara T, Nishimata H, Tanaka S, Higashi M, Yonezawa S
    • Organizer
      International Symposium on Pancreas Cancer 2012
    • Place of Presentation
      京都国際コンベンションセンター (京都)
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] 膵内分泌腫瘍におけるMUC17発現の検討2012

    • Author(s)
      東美智代、北本祥、横山勢也、田畑和宏、北薗育美、平木翼、米澤傑
    • Organizer
      日本病理学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24590447
  • [Presentation] MUC1 enhances hypoxia-driven angiogenesis through the regulation of multiple proangiogenic factors.2012

    • Author(s)
      Kitamoto S, Yokoyama S, Higashi M, Yamada N, Takao S, Yonezawa S
    • Organizer
      International Symposium on Pancreas Cancer 2012
    • Place of Presentation
      京都国際コンベンションセンター (京都)
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] CTGF is enhanced by hypoxia through nuclear recruitment of MUC1 in pancreatic cancer.2012

    • Author(s)
      Kitamoto S, Higashi M, Yokoyama S, Takao S, Yonezawa S
    • Organizer
      22nd Biennial Congress of the European Association for Cancer Research
    • Place of Presentation
      バルセロナ国際会議場 (Barcelona, Spain )
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] 膵内分泌腫瘍におけるMUC17発現の検討2012

    • Author(s)
      東美智代、北本 祥、横山勢也、田畑和宏、   北薗育美、平木 翼、米澤 傑
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル (東京)
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] 胆道の前癌病変について 粘液形質の観点から2012

    • Author(s)
      東美智代
    • Organizer
      胆道学会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590447
  • [Presentation] 胃癌細胞(por2、sig)の検出に有用な新しいモノクローナル抗体「MUC1-014E」(第2報):生検標本への応用2012

    • Author(s)
      米澤 傑、北島信一、東美智代、堀之内道子、 横山勢也、北本 祥、田村幸大、清水 健、    後藤正道
    • Organizer
      第101回日本病理学会総会
    • Place of Presentation
      京王プラザホテル (東京)
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] 膵胆管系腫瘍-難治性腫瘍-の早期診断システム確立への挑戦2011

    • Author(s)
      東美智代, 他
    • Organizer
      第52回日本組織細胞化学会総会・学術総会(招待講演)
    • Place of Presentation
      金沢大学宝町キャンパス(石川県)
    • Year and Date
      2011-09-25
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] 膵胆管系腫瘍-難治性腫瘍-の早期診断システム確立への挑戦2011

    • Author(s)
      東美智代, 他
    • Organizer
      第52回日本組織細胞化学会総会・学術集会
    • Place of Presentation
      金沢大学宝町キャンパス(石川県)
    • Year and Date
      2011-09-25
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] 浸潤性膵管癌におけるMUC17発現の検討2011

    • Author(s)
      東美智代, 他
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2011-04-28
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] Immunohistochemical study of MUC17 expression in human pancreatic cancer2011

    • Author(s)
      Higashi, M., et al.
    • Organizer
      International Symposium on Pancreatic Cancer
    • Place of Presentation
      鹿児島大学(鹿児島市)
    • Year and Date
      2011-02-18
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] Immunohistochemical study of MUC17 expression in human pancreatic cancer2011

    • Author(s)
      Higashi, M., et al.
    • Organizer
      23rd European Congress of Pathology
    • Place of Presentation
      Helsinki Exhibition & Convention Center (Helsinki, Finland)
    • Year and Date
      2011-08-29
    • Data Source
      KAKENHI-PROJECT-23390085
  • [Presentation] Immonohistochemical study of MUC17 expression in human pancreatic cancer/2011/Eurpean congress of pathology2011

    • Author(s)
      Higashi, M., et al
    • Organizer
      23^<rd> European Congress of Pathology
    • Place of Presentation
      Helsinki Exhibition & Convention Center (Helsinki, Finland)
    • Year and Date
      2011-08-29
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] 膵胆管系腫瘍-難治性腫瘍-の早期診断システム確立への挑戦/2011/組織細胞化学会2011

    • Author(s)
      東美智代, 他
    • Organizer
      第52回日本組織細胞化学会総会・学術総会
    • Place of Presentation
      金沢大学宝町キャンパス(石川県)(招待講演)
    • Year and Date
      2011-09-25
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] Immonohistochemical study of MUC17 expression in human pancreatic cancer2011

    • Author(s)
      Higashi, M., et al
    • Organizer
      23rd European Congress of Pathology
    • Place of Presentation
      Helsinki Exhibition & Convention Center(Helsinki, Finland)
    • Year and Date
      2011-08-29
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] 膵疾患診断におけるEUS-FNABの検討2010

    • Author(s)
      東美千代, 他
    • Organizer
      第49回日本臨床細胞学会秋季大会
    • Place of Presentation
      神戸国際展示場3号館(兵庫)
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Presentation] 膵疾患診断におけるEUS-FNABの検討2010

    • Author(s)
      東美智代, 他
    • Organizer
      第49回日本臨床細胞学会秋季大会
    • Place of Presentation
      神戸国際展示場3号館 (神戸市)
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] MUC16 (CA125) is a novel prognostic factor of intrahepatic cholangiocarcinoma-mass forming type2010

    • Author(s)
      Higashi, M., et al.
    • Organizer
      第56回日本病理学会秋期特別総会
    • Place of Presentation
      北九州国際会議場(福岡)
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Presentation] Immunohistochemical study of mucin expression in Periampullary adenomyoma : Application of immunohistochemical examination for surgical treatment2010

    • Author(s)
      Higashi, M., et al.
    • Organizer
      2010 Focus in surgery meeting
    • Place of Presentation
      Gansu Ningwozhuang Hotel(中国蘭州)
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] 膵疾患診断におけるEUS-FNAの有用性の検討2010

    • Author(s)
      東美智代, 他
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] MUC16(CA125) is a novel prognostic factor of intrahepatic cholangiocarcinoma-mass forming type2010

    • Author(s)
      Higashi, M., et al.
    • Organizer
      第56回日本病理学会秋期特別総会
    • Place of Presentation
      北九州国際会議場 (北九州市)
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] MUC16(CA125) is a novel prognostic factor of intrahepatic cholangiocarcinoma-mass forming type2010

    • Author(s)
      Higashi, M., et al
    • Organizer
      第56回日本病理学会秋期特別総会
    • Place of Presentation
      北九州国際会議場(福岡)
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] 膵疾患診断におけるEUS-FNAの有用性の検討2010

    • Author(s)
      東美千代, 他
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Presentation] 膵がんに対する病理診断の動向と展望2009

    • Author(s)
      米澤傑、東美智代、山田宗茂、後藤正道
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)(シンポジウム)
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Presentation] 膵IPMNの亜分類と長期予後2009

    • Author(s)
      東美智代, 他
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都国際会館(京都)
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] The expression of MUC16(CA125)in intrahepatic bile duct tumors2009

    • Author(s)
      東美智代, et al
    • Organizer
      MUCHINS IN HEALTH AND DISEASE(10th International Workshop on Carcinoma-associated Mucins)
    • Place of Presentation
      KING'S college, Cambridge, (London, UK)
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] The expression of MUC16(CA125) in intrahepatic bile duct tumors2009

    • Author(s)
      Higashi, M., et al
    • Organizer
      MUCHINS IN HEALTH AND DISEASE(10th International Workshop on Carcinoma-associated Mucins)
    • Place of Presentation
      KING's college, Cambridge,(London, UK)
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] The expression of MUC16 (CA125) in intrahepatic bile duct tumors2009

    • Author(s)
      Higashi, M., et al.
    • Organizer
      MUCHINS IN HEALTH AND DISEASE (10th International Workshop on Carcinoma-associated Mucins)
    • Place of Presentation
      Robinson college, Univ. Cambridge (Cambridge, UK)
    • Data Source
      KAKENHI-PROJECT-20014022
  • [Presentation] CpG methylation in the distal region of MUC5AC promoter contribute to the regulation of MUC5AC2009

    • Author(s)
      山田宗茂, 東美智代, 他
    • Organizer
      第68回日本癌学会総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Data Source
      KAKENHI-PROJECT-21590399
  • [Presentation] The expression of MUC16(CA125)in intrahepatic bile duct tumors2009

    • Author(s)
      Higashi, M., et al.
    • Organizer
      MUCHINS IN HEALTH AND DISEASE(10th International Workshop on Carcinoma-associated Mucins)
    • Place of Presentation
      Robinson college, Univ.Cambridge(Cambridge, UK)
    • Data Source
      KAKENHI-PROJECT-20590345
  • [Presentation] 膵液中ムチン遺伝子メチル化解析の膵悪性腫瘍診断マーカーへの応用

    • Author(s)
      新原亨、東美智代、米澤傑
    • Organizer
      第46回日本膵臓学会大会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-06-19 – 2015-06-20
    • Data Source
      KAKENHI-PROJECT-26290048
  • [Presentation] EUS-FNA検体を用いたムチン染色有用性の検討

    • Author(s)
      東美智代、畑中一仁、竹下かおり、西田ゆかり、舞木公子、田中和彦、北島信一
    • Organizer
      臨床細胞学会
    • Place of Presentation
      神奈川(パシフィコ横浜)
    • Year and Date
      2014-06-05 – 2014-06-07
    • Data Source
      KAKENHI-PROJECT-24590447
  • [Presentation] 膵漿液性腫瘍の病理

    • Author(s)
      東美智代
    • Organizer
      日本病理学会
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Year and Date
      2015-04-30 – 2015-05-02
    • Data Source
      KAKENHI-PROJECT-24590447
  • 1.  YOKOYAMA Seiya (20569941)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 70 results
  • 2.  YONEZAWA Suguru (10175002)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 60 results
  • 3.  GOTO Masamichi (80325779)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 13 results
  • 4.  谷本 昭英 (10217151)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 8 results
  • 5.  NOMOTO Mitsuharu (20274813)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  Hamada Taiji (30771480)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 7.  Fukukura Yoshihiko (50315412)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 8.  Ohtsuka Takao (20372766)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 9.  永田 耕治 (80398289)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  吉浦 敬 (40322747)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 11.  杉本 知之 (70324829)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  赤羽 俊章 (70754480)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  SHINCHI Hiroyuki (60284874)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NARIMATSU Hisashi (40129581)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KAMEYAMA Akihiko (80415661)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  hayashi sadao (10549918)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  TSUYAMA hinichiro (30041346)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TAKAO Sonshin (80171411)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  AIKOU Takashi (60117471)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  原 太郎 (20535869)
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    # of Collaborated Products: 1 results
  • 21.  松下 能文 (90244227)
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  • 22.  内匠 浩二 (50535820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  袴田 裕人 (20727565)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  中條 正豊 (00594631)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  中村 文彦 (00595738)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  井手上 淳一 (50642617)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  熊谷 雄一 (40572160)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 28.  飛田 陽 (10435026)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  山口 浩 (20510697)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  三森 功士 (50322748)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 31.  蔵原 弘 (70464469)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 32.  又木 雄弘 (10444902)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 33.  井手野 昇 (90883421)
    # of Collaborated Projects: 1 results
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  • 34.  上村 清央 (30593652)
    # of Collaborated Projects: 1 results
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  • 35.  岩永 崇 (40444830)
    # of Collaborated Projects: 1 results
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  • 36.  古川 龍彦 (40219100)
    # of Collaborated Projects: 1 results
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  • 37.  盛 真一郎 (00620519)
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    # of Collaborated Products: 1 results
  • 38.  福長 洋介 (50731139)
    # of Collaborated Projects: 1 results
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  • 39.  濱元 宏喜 (60825818)
    # of Collaborated Projects: 1 results
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  • 40.  郡山 千早 (30274814)
    # of Collaborated Projects: 1 results
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  • 41.  田辺 寛 (40814306)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  和田 真澄 (60836112)
    # of Collaborated Projects: 1 results
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  • 43.  MATSUO KEI
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 44.  KITA Yoshiaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 45.  保坂 優斗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  田上 聖徳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 47.  杉浦 剛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  後藤 雄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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