Taira Toki 平良東紀

… Alternative Names

TAIRA Toki 平良東紀

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Researcher Number	60315463
Other IDs
External Links
Affiliation (Current)	2025: 琉球大学, 農学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 琉球大学, 農学部, 教授 2008 – 2012: 琉球大学, 農学部, 准教授 2009: 国立大学法人琉球大学, 農学部, 准教授
Review Section/Research Field	Principal Investigator Living organism molecular science Except Principal Investigator Medium-sized Section 27:Chemical engineering and related fields / Basic Section 38010:Plant nutrition and soil science-related / Environmental technology/Environmental materials / Parasitology (including Sanitary zoology)
Keywords	Principal Investigator 酵素 / 植物 / 抗真菌活性 / キチナーゼ / タンパク質工学 / 構造活性相関 Except Principal Investigator 抗真菌剤 / 翻訳後修飾 / 架橋酵素 / パルミトイル化 … More / ラフト / 脂質修飾タンパク / 細胞壁 / 細胞膜 / 両親媒性タンパク質 / オミックス / 昆虫 / 植物 / GM植物 / 抗昆虫 / 農業 / 防御 / 乳管細胞 / 乳液 / 抗菌活性 / 抗真菌薬 / 抗菌製剤 / 脂質化タンパク質 / 相分離 / 抗真菌活性 / リポソーム / タンパク質 / バイオ界面 / 脂質修飾 / 両親媒性 / 藻類養殖 / 循環再生加工 / 環境技術 / 削減 / 二酸化炭素 / 炭素回生 / バイオ燃料 / 海藻 / 二酸化炭素削減 / バイオマス / 海洋 / 標的化 / 抗原提示 / デリバリー分子 / 分子設計 / コンポーネントワクチン / インフルエンザ / 感染防御 / メロゾイトワクチン / 伝搬阻止ワクチン / ワクチンプラットフォーム / デリバリーシステム / アジュバント / ワクチン / マラリア Less

Functional design of amphiphilic artificial proteins working at heterologous cellular interfaces
- Principal Investigator
  
  神谷典穂
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 27:Chemical engineering and related fields
- Research Institution
  Kyushu University
Discovering novel plant defense proteins and elucidating their mechanisms of action in plants with laticifers as a beginning.
- Principal Investigator
  
  Kitajima Sakihito
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38010:Plant nutrition and soil science-related
- Research Institution
  Kyoto Institute of Technology
Exploring the novel properties of proteins by controlling the partial hydrophobicity
- Principal Investigator
  
  Kamiya Noriho
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 27:Chemical engineering and related fields
- Research Institution
  Kyushu University
The study of the stabilization of carbon dioxide and the development of new energy through the use of marine biomass
- Principal Investigator
  
  SENAHA Izuru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental technology/Environmental materials
- Research Institution
  University of the Ryukyus
Studies on relationship between structure and antifungal activity of plant chitinases with aid of diversity of genes from subtropical plants.Principal Investigator
- Principal Investigator
  
  TAIRA Toki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  University of the Ryukyus
Development of molecular adjuvants for design of malaria vaccines
- Principal Investigator
  
  ARAKAWA Takeshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  University of the Ryukyus

All 2024 2023 2022 2021 2020 2011 2010 2009

All Journal Article Presentation Patent

[Journal Article] Design of Protease-Responsive Antifungal Liposomal Formulation Decorated with a Lipid-Modified Chitin-Binding Domain2024
- Author(s)
  Saputra Hendra、Safaat Muhammad、Santoso Pugoh、Wakabayashi Rie、Goto Masahiro、Taira Toki、Kamiya Noriho
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 7 Pages: 3567-3567
- DOI
  10.3390/ijms25073567
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23H00247
[Journal Article] Enhancement of the Antifungal Activity of Chitinase by Palmitoylation and the Synergy of Palmitoylated Chitinase with Amphotericin B2022
- Author(s)
  Santoso Pugoh、Minamihata Kosuke、Ishimine Yugo、Taniguchi Hiromasa、Komada Takuya、Sato Ryo、Goto Masahiro、Takashima Tomoya、Taira Toki、Kamiya Noriho
- Journal Title
  
  ACS Infectious Diseases
  
  Volume: 8 Issue: 5 Pages: 1051-1061
- DOI
  10.1021/acsinfecdis.2c00052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H00841, KAKENHI-PROJECT-21H04631, KAKENHI-PROJECT-21J12611
[Journal Article] Liposomal Amphotericin B Formulation Displaying Lipid-Modified Chitin-Binding Domains with Enhanced Antifungal Activity2022
- Author(s)
  Taniguchi Hiromasa、Ishimime Yugo、Minamihata Kosuke、Santoso Pugoh、Komada Takuya、Saputra Hendra、Uchida Kazuki、Goto Masahiro、Taira Toki、Kamiya Noriho
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 19 Issue: 11 Pages: 3906-3914
- DOI
  10.1021/acs.molpharmaceut.2c00388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H00841, KAKENHI-PROJECT-21H04631
[Journal Article] Preparation of amphotericin B-loaded hybrid liposomes and the integration of chitin-binding proteins for enhanced antifungal activity2022
- Author(s)
  Santoso Pugoh、Komada Takuya、Ishimine Yugo、Taniguchi Hiromasa、Minamihata Kosuke、Goto Masahiro、Taira Toki、Kamiya Noriho
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 134 Issue: 3 Pages: 259-263
- DOI
  10.1016/j.jbiosc.2022.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H00841, KAKENHI-PROJECT-21H04631
[Journal Article] Orthogonal Enzymatic Conjugation Reactions Create Chitin Binding Domain Grafted Chitinase Polymers with Enhanced Antifungal Activity2021
- Author(s)
  Minamihata Kosuke、Tanaka Yusuke、Santoso Pugoh、Goto Masahiro、Kozome Dan、Taira Toki、Kamiya Noriho
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 32 Issue: 8 Pages: 1688-1698
- DOI
  10.1021/acs.bioconjchem.1c00235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H00841
[Journal Article] Chitin-related enzymes in agro-biosciences.2011
- Author(s)
  Arakane Y., Taira T., Ohnuma T., Fukamizo T.
- Journal Title
  
  Curr Drug Targets in press
- Data Source
  KAKENHI-PROJECT-21710234
[Journal Article] Cloning and characterization of a small family 19 chitinase from moss(Bryum coronatum).2011
- Author(s)
  Taira T, Mahoe Y, Kawamoto N, Onaga S, Iwasaki H, Ohnuma T, Fukamizo T.
- Journal Title
  
  Glycobiology. 21
  
  Pages: 644-654
- Data Source
  KAKENHI-PROJECT-21710234
[Journal Article] Cloning and characterization of a small family 19 chitinase from moss (Bryum coronatum)2011
- Author(s)
  Toki Taira
- Journal Title
  
  Glycobiology
  
  Volume: 21 Pages: 644-654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21710234
[Journal Article] Structures and antifungal activity of plant chitinases.2010
- Author(s)
  Taira T
- Journal Title
  
  J.Appl.Glycosci. 57
  
  Pages: 167-176
- NAID
  10026552018
- Data Source
  KAKENHI-PROJECT-21710234
[Journal Article] Transglycosylation reaction catalyzed by a class V chitinase fromcycad. Cycas revoluta.2010
- Author(s)
  Toki Taira
- Journal Title
  
  Biochim.Biophys.Acta. 1804
  
  Pages: 668-675
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21710234
[Journal Article] Structures and Antifungal Activity of Plant Chitinases2010
- Author(s)
  Toki Taira
- Journal Title
  
  Journal of applied glycoscience
  
  Volume: 57 Pages: 167-176
- NAID
  10026552018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21710234
[Journal Article] A plant class V chitinase from a cycad (Cycas revoluta).2009
- Author(s)
  Toki Taira
- Journal Title
  
  Glycobiology 19
  
  Pages: 1452-1461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21710234
[Journal Article] A plant class V chitinase from a cycad(Cycas revoluta) : biochemical characterization, cDNA isolation, and posttranslational modification.2009
- Author(s)
  Taira T, Hayashi H, Tajiri Y, Onaga S, Uechi G, Iwasaki H, Ohnuma T, Fukamizo T.
- Journal Title
  
  Glycobiology 19
  
  Pages: 1452-1461
- Data Source
  KAKENHI-PROJECT-21710234
[Patent] 抗真菌剤組成物、化合物及び抗真菌剤2020
- Inventor(s)
  神谷典穂、平良東紀
- Industrial Property Rights Holder
  国立大学法人九州大学・琉球大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-151325
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19H00841
[Presentation] Biomolecular Engineering by Artificial Protein Lipidation2023
- Author(s)
  Noriho Kamiya, Rie Wakabayashi, Toki Taira
- Organizer
  The 14th AFOB Regional Symposium (ARS2023)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00247
[Presentation] Design of Lipid-based Bioconjugates with Antifungal Activity2023
- Author(s)
  Noriho Kamiya, Hendra Saputra, Pugoh Santoso, Rie Wakabayashi, Toki Taira
- Organizer
  Young Asian Biological Engineer’s Community (YABEC) 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00247
[Presentation] Synergistic antifungal activity by combining Amphotericin B with lipidated chitinase2022
- Author(s)
  Pugoh Santoso, Kosuke Minamihata, Yugo Ishimine, Hiromasa Taniguchi, Ryo Sato, Masahiro Goto, Tomoya Takashima, Toki Taira, Noriho Kamiya
- Organizer
  APCChE 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00841
[Presentation] 脂質化によるキチナーゼの抗真菌活性の増強ならびに脂質化キチナーゼのアンフォテリシンBとの相乗効果2022
- Author(s)
  Pugoh Santoso、南畑孝介、石嶺悠悟、谷口浩誠、佐藤崚、後藤雅宏、髙島智也、平良東紀、神谷典穂
- Organizer
  化学工学会第87年会
- Data Source
  KAKENHI-PROJECT-19H00841
[Presentation] Design of Chitinase-based Antifungal Bioconjugates2021
- Author(s)
  Noriho Kamiya, Pugoh Santoso, Taniguchi Hiromasa, Yugo Ishimine, Kosuke Minamihata, Tomoya Takashima, Toki Taira
- Organizer
  The 26th Symposium of Young Asian Biological Engineers’ Community (YABEC2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00841
[Presentation] 真菌特異性を付与した新規抗真菌薬の設計とその機能評価2021
- Author(s)
  谷口浩誠、 PugohSantoso、佐藤崚、南畑孝介、石嶺悠悟、平良東紀、神谷典穂
- Organizer
  日本生物工学会九州支部大分大会
- Data Source
  KAKENHI-PROJECT-19H00841
[Presentation] Synergistic Antifungal Action of Lipid-Modified Chitinase With Amphotericin-B2021
- Author(s)
  Pugoh Santoso, Takuya Komada, Hiromasa Taniguchi, Yugo Ishimine, Ryo Sato, Kosuke Minamihata, Tomoya Takashima, Toki Taira, Noriho Kamiya
- Organizer
  International Chemical Engineering Symposia 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H00841
[Presentation] 新規抗真菌薬の創出に向けた脂質修飾タンパク質含有製剤の設計2021
- Author(s)
  谷口浩誠、PugohSantoso、佐藤崚、南畑孝介、石嶺悠悟、平良東紀、神谷典穂
- Organizer
  化学工学会第52回秋季大会
- Data Source
  KAKENHI-PROJECT-19H00841
[Presentation] 酵素触媒を用いた脂質修飾キチナーぜの調製と抗真菌活性の評価2020
- Author(s)
  谷口浩誠、Pugoh Santoso、駒田拓也、佐藤崚、南畑孝介、石嶺悠悟、平良東紀、神谷典穂
- Organizer
  化学工学会第51回秋季大会
- Data Source
  KAKENHI-PROJECT-19H00841
[Presentation] パイナップル緑葉由来キチナーゼ-Cのキチン結合活性および抗真菌活性に関わる構造2011
- Author(s)
  平良東紀, 秋元理沙
- Organizer
  日本農芸化学会2011年度大会
- Place of Presentation
  京都
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21710234
[Presentation] パイナップル緑葉由来キチナーゼ-Cのキチン結合活性および抗真菌活性に関わる構造2011
- Author(s)
  平良東紀
- Organizer
  日本農芸化学会2011年度大会
- Place of Presentation
  京都府(京都女子大学)
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21710234
[Presentation] Development of absorption and recirculation system of CO2 by marine biomass2010
- Author(s)
  瀬名波出, 平岡雅紀, 小西照子, 平良東紀
- Organizer
  International Workshop on Process Intensification 2010
- Place of Presentation
  九州大学,福岡県
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22310057
[Presentation] 海洋バイオマスを利用した CO2回収・リサイクル技術の開発2010
- Author(s)
  瀬名波出,小西照子,平良東紀
- Organizer
  2010年度日本機会学会年次大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22310057
[Presentation] 植物クラスVキチナーゼの構造と機能2010
- Author(s)
  水原麻美子, 桐山真, 澤井章人, 大沼貴之, 平良東紀, 深溝慶
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21710234
[Presentation] 植物由来新規キチナーゼおよび植物キチナーゼのクラス分類について2010
- Author(s)
  平良東紀
- Organizer
  第24回キチン・キトサンシンポジウム
- Place of Presentation
  東京都(東京大学弥生講堂)
- Year and Date
  2010-07-14
- Data Source
  KAKENHI-PROJECT-21710234
[Presentation] Development of absorption and recirculation system of CO2 by marine biomass2010
- Author(s)
  瀬名波出,平岡雅紀,小西照子,平良東紀
- Organizer
  International Workshop on Process Intensification 2010
- Place of Presentation
  九州大学,福岡
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22310057
[Presentation] 植物由来新規キチナーゼおよび植物キチナーゼのクラス分類について2010
- Author(s)
  平良東紀, 翁長彰子, 伊藤進
- Organizer
  第24回キチン・キトサンシンポジウム
- Place of Presentation
  東京
- Year and Date
  2010-07-14
- Data Source
  KAKENHI-PROJECT-21710234
[Presentation] 海洋バイオマスを利用したCO2回収・リサイクル技術の開発2010
- Author(s)
  瀬名波出, 小西照子, 平良東紀
- Organizer
  2010年度日本機会学会年次大会
- Place of Presentation
  名古屋工業大学,愛知県
- Year and Date
  2010-11-30
- Data Source
  KAKENHI-PROJECT-22310057
[Presentation] Antifungal activity of plant GH family 19 chitinases.2009
- Author(s)
  Toki Taira
- Organizer
  The 11th International Conference on Chitin and Chitosan
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-21710234
[Presentation] 植物キチナーゼの構造と抗真菌活性との相関2009
- Author(s)
  平良東紀
- Organizer
  日本農芸化学会西日本支部・中四国支部・関西支部、日本栄養食糧学会九州・沖縄支部、及び日本食品科学工学会西日本支部合同大会シンポジウム
- Place of Presentation
  沖縄
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21710234
[Presentation] 植物由来クラスVキチナーゼの酵素学的性質2009
- Author(s)
  大沼貴之, 水原麻美子, 平良東紀, Karen Skriver, 深溝慶
- Organizer
  第23回キチン・キトサン・シンポジウム
- Place of Presentation
  佐賀
- Year and Date
  2009-08-21
- Data Source
  KAKENHI-PROJECT-21710234
[Presentation] 植物由来FamilyGH-19キチナーゼのキチンオリゴ分解様式2009
- Author(s)
  福田達也, 大沼貴之, 平良東紀, 深溝慶
- Organizer
  日本農芸化学会西日本支部・中四国支部・関西支部、日本栄養食糧学表会九州・沖縄支部、及び日本食品科学工学会西日本支部合同大会
- Place of Presentation
  沖縄
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-21710234
[Presentation] 植物キチナーゼの構造と抗真菌活性との相関2009
- Author(s)
  平良東紀
- Organizer
  日本農芸化学会西日本支部・中四国支部・関西支部合同大会シンポジウム
- Place of Presentation
  ロワジールホテル那覇,沖縄
- Data Source
  KAKENHI-PROJECT-21710234
[Presentation] Antifungal activity of plant GH family 19 chitinases.2009
- Author(s)
  Taira T, Akimoto R, Yamagami T.
- Organizer
  The 11th International Conference on Chitin and Chitosan.
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2009-09-07
- Data Source
  KAKENHI-PROJECT-21710234
[Presentation] ミドリカタヒバ(Selaginella doederleinii)由来新規キチナーゼの性質および一次構造2009
- Author(s)
  久場由真仁, 平良東紀, 伊藤進
- Organizer
  第23回キチン・キトサン・シンポジウム
- Place of Presentation
  佐賀
- Year and Date
  2009-08-21
- Data Source
  KAKENHI-PROJECT-21710234

1. Kamiya Noriho (50302766)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
2. 若林里衣 (60595148)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. ARAKAWA Takeshi (50305190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MIYATA Takeshi (20448591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TSUBOI Takafumi (00188616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SENAHA Izuru (70253945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. KONISHI Teruko (30433098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. TAMAKI Shirou (80163666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. FUJIMURA Hiroyuki (20398308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ISHIKAWA Masaaki (00398306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. WAKAI Kensuke (10314741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OOSHIRO Naoki (10295298)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ODA Takuya (20505929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HIRAOKA Masanori (30380306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. HARADA Syusaku (80315168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Kitajima Sakihito (70283653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 小濱秀泰 (10514581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 吉田英樹 (30570600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Taira Toki 平良 東紀

TAIRA Toki 平良 東紀

Research Projects

Research Products

Co-Researchers

Functional design of amphiphilic artificial proteins working at heterologous cellular interfaces

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Discovering novel plant defense proteins and elucidating their mechanisms of action in plants with laticifers as a beginning.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploring the novel properties of proteins by controlling the partial hydrophobicity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study of the stabilization of carbon dioxide and the development of new energy through the use of marine biomass

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on relationship between structure and antifungal activity of plant chitinases with aid of diversity of genes from subtropical plants.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of molecular adjuvants for design of malaria vaccines

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Design of Protease-Responsive Antifungal Liposomal Formulation Decorated with a Lipid-Modified Chitin-Binding Domain2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhancement of the Antifungal Activity of Chitinase by Palmitoylation and the Synergy of Palmitoylated Chitinase with Amphotericin B2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Liposomal Amphotericin B Formulation Displaying Lipid-Modified Chitin-Binding Domains with Enhanced Antifungal Activity2022

Author(s)

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[Journal Article] Preparation of amphotericin B-loaded hybrid liposomes and the integration of chitin-binding proteins for enhanced antifungal activity2022

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[Journal Article] Orthogonal Enzymatic Conjugation Reactions Create Chitin Binding Domain Grafted Chitinase Polymers with Enhanced Antifungal Activity2021

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[Journal Article] Chitin-related enzymes in agro-biosciences.2011

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[Journal Article] Cloning and characterization of a small family 19 chitinase from moss(Bryum coronatum).2011

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[Journal Article] Cloning and characterization of a small family 19 chitinase from moss (Bryum coronatum)2011

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[Journal Article] Structures and antifungal activity of plant chitinases.2010

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Taira Toki 平良東紀

TAIRA Toki 平良東紀