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Fujimoto Yasuyuki  藤本 康之

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FUJIMOTO Yasuyuki  藤本 康之

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Researcher Number 60317724
Other IDs
External Links
Affiliation (Current) 2025: 岩手医科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help 2010 – 2012: 岩手医科大学, 薬学部, 准教授
2007 – 2008: Iwate Medical University, 薬学部, 准教授
1999 – 2006: Teikyou Univ., Fac.of Pharm.Sci., Research Associate, 薬学部, 助手
2005: Teikyo Univ., Pharm.Sci, Ass.Res., 助手
Review Section/Research Field
Principal Investigator
Biological pharmacy / Biological pharmacy
Except Principal Investigator
Biological pharmacy
Keywords
Principal Investigator
脂肪滴 / アシルCoA合成酵素 / 中性脂質 / 細胞内脂質顆粒 / 受容体 / 蛍光 / アドレナリン受容体 / リパーゼ / 中世脂質 / 蛍光標識 … More / GFP / 脂質代謝 / 脂肪酸 / MS / LC MC / ADRP / 中性脂肪 / ダウンレギュレーション / 阻害剤 / グリセロール / グルコース / 肝細胞 / 間接蛍光抗体法 / 泡沫細胞 / マクロファージ / 動脈硬化 … More
Except Principal Investigator
動脈硬化 / モノクローナル抗体 / マクロファージ / 過酸化脂質 / oxidized LDL / LCAT / 泡沫細胞 / Monoclonal antibody / Macrophage / 腎疾患 / 酸化リポタンパク質 / 体外診断薬 / リポタンパク質 / Atherogenesis / Hyperlipidemia / Foam cell / Necrosis / Apoptosis / 脂質球 / コレステロール / リン脂質 / 256C抗体 / 動脈硬化進展 / 高脂血症 / ネクローシス / アポトーシス / Atherectomy / Macorphage / Myocardial infarction / モリクローナル抗体 / ELISA / 免疫組織化学 / 心筋梗塞 / foam cell / monoclonal antibody / oxidized PC / lipoprotein / atherosclerosis / 酸化燐脂質 / 酸化LDL / Phosphatidylcholine / Lipoprotein / Oxidized LDL / 賢疾患 / リソソーム / フォスファチジルコリン Less
  • Research Projects

    (8 results)
  • Research Products

    (38 results)
  • Co-Researchers

    (9 People)
  •  Visualization ofβ3 adrenoceptor signaling for development of ligand screening.Principal Investigator

    • Principal Investigator
      FUJIMOTO Yasuyuki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Iwate Medical University
  •  Analysis of lipid-droplet-formation mechanisms related withlipid-metabolic enzymes in lipid dropletsPrincipal Investigator

    • Principal Investigator
      FUJIMOTO Yasuyuki
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Iwate Medical University
      Teikyo University
  •  肝細胞内脂質顆粒蛋白のプロテオーム解析を基盤とした細胞内中性脂質貯蔵機構の解明Principal Investigator

    • Principal Investigator
      藤本 康之
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Teikyo University
  •  Foam cell rupture may involve in the development of atheroma

    • Principal Investigator
      TATSUYA Takano
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Teikyo University
  •  動脈硬化病巣におけるマクロファージ泡沫細胞の細胞内脂質貯蔵機構の解析Principal Investigator

    • Principal Investigator
      藤本 康之
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Teikyo University
  •  Oxidized lipoproteins released from atherosclerotic lesions

    • Principal Investigator
      TAKANO Tatsuya
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Teikyo University
  •  Novel diagnosis of oxidized LDL in serum using monoclonal antibody

    • Principal Investigator
      TAKANO Tatsuya
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Teikyo University
  •  Metabolism of Oxidized Low Density Lipoprotein by Lecithin-Colesterol Acyltransferse

    • Principal Investigator
      TAKANO Tatsuya
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Teikyo University

All 2012 2011 2010 2008 2007 2006 2004 Other

All Journal Article Presentation

  • [Journal Article] Transporter Associated with Antigen Processing-Like (ABCB9) Stably Expressed in Chinese Hamster Ovary-K1 Cells Is Sorted to the Microdomains of Lysosomal Membranes2011

    • Author(s)
      Fujimoto Y., Kamakura A., Motohashi Y., Ohashi-Kobayashi A. and Maeda M
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 34 Issue: 1 Pages: 36-40

    • DOI

      10.1248/bpb.34.36

    • NAID

      130000402259

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590069
  • [Journal Article] Convergent synthesis of fluorescence-labeled probes of Annonaceous acetogenins and visualization of their cell distribution.2010

    • Author(s)
      Kojima N., Morioka T., Urabe D., Yano M, Suga Y., Maezaki N., Ohashi-Kobayashi A., Fujimoto Y., Maeda M., Yamori T., Yoshimitsu T., Tanaka T.
    • Journal Title

      Bioorg.Med.Chem.

      Volume: 18(24) Pages: 8630-8641

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590069
  • [Journal Article] Convergent synthesis of fluorescence-labeled probes of Annonaceous acetogenins and visualization of their cell distribution2010

    • Author(s)
      Kojima N, Morioka T, Urabe D, Yano M, Suga Y, Maezaki N, Ohashi-Kobayashi A, Fujimoto Y, Maeda M, Yamori T, Yoshimitsu T, Tanaka T
    • Journal Title

      Bioorg Med Chem

      Volume: 18(24) Issue: 24 Pages: 8630-8641

    • DOI

      10.1016/j.bmc.2010.10.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22390021, KAKENHI-PROJECT-22590069, KAKENHI-PROJECT-22590070
  • [Journal Article] Functional dissection of transmembrane domains of human TAP-like(ABCB9)2008

    • Author(s)
      Kamakura A, Fujimoto Y., Motohashi Y., Ohashi K., Ohashi-Kobayashi A. and Maeda M
    • Journal Title

      Biochem. Biophys. Res. Commun 377(3)

      Pages: 847-851

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] Molecular pathology in atherosclerosis : the mechanism how cholesteryl ester accumulates in atheromatous aorta2008

    • Author(s)
      Takano T., Itabe H., Mori M., Kimura J., Nakagami K., Sato R., Hashita R., Yagyu Y., Mineo C., Amanuma K., Imanaka T., Higashi Y., Fujimoto Y. and Fujita E
    • Journal Title

      Yakugaku Zasshi 128

      Pages: 1383-1401

    • NAID

      110006935748

    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] Functional dissection of transmembrane domains of human TAP-like (ABCB9)2008

    • Author(s)
      Kamakura A., Fujimoto Y., Motohashi Y., Ohashi K., Ohashi-Kobayashi A, Maeda M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 377(3)

      Pages: 847-851

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] アシル-CoA合成酵素に着目した細胞内中性脂質蓄積機構の研究2008

    • Author(s)
      藤本康之
    • Journal Title

      医科学応用研究財団研究報告 25

      Pages: 308-311

    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] Up-regulation of microtubule-associated protein 2 accompanying the filial imprinting of domestic chicks (Gallus gallus domesticus)2008

    • Author(s)
      Yamaguchi S., Fujii-Taira I., Murakami A., Hirose N., Aoki N., Izawa E., Fujimoto Y., Takano T., Matsushima T. and Homma K. J
    • Journal Title

      Brain Res. Bulletin 76(3)

      Pages: 282-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] Up-regulation of microtubule-associated protein 2 accompanying the filial imprinting of domestic chicks (Gallus gallus domesticus).2008

    • Author(s)
      Yamaguchi S., Fujii-Taira I., Murakami A., Hirose N., Aoki N., Izawa E., Fujimoto Y. Takano T., Matsushima T., Homma K. J.
    • Journal Title

      Brain Res. Bulletin 76(3)

      Pages: 282-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] Gene expression profile in cerebrum in the filial imprinting of domestic chicks (Gallus gallus domesticus).2008

    • Author(s)
      Yamaguchi S., Fujii-Taira I., Kalagiri S., Izawa E., Fujimoto Y., Takeuchi H., Takano T., Malsushima T., Homma K, J.
    • Journal Title

      Brain Res. Bulletin 76(3)

      Pages: 275-281

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] J. Gene expression profile in cerebrum in the filial imprinting of domestic chicks(Gallus gallus domesticus)2008

    • Author(s)
      Yamaguchi S., Fujii-Taira I., Katagiri S., Izawa E., Fujimoto Y., Takeuchi H., Takano T., Matsushima T. and Homma K.
    • Journal Title

      Brain Res. Bulletin 76(3)

      Pages: 275-281

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] Involvement of ACSL in local synthesis of neutral lipids in cytoplasmic lipid droplets in human hepatocyte HuH7.2007

    • Author(s)
      Fujimoto Y., Itabe H., Kinoshita T., Homma K.J., Onoduka J., Mori M., Yamaguchi S., Makita M., Higashi Y., Yamashita A. and Takano T.
    • Journal Title

      J. Lipid Res. 48

      Pages: 1280-1292

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] J. In vivo gene transfer into newly-hatched chick brain by electroporation2007

    • Author(s)
      Yamaguchi S., Katagiri S., Hirose N., Fujimoto Y., Mori M., Fujii-Taira I., Takano T., Matsushima T. and Homma K.
    • Journal Title

      NeuroReport 18(8)

      Pages: 735-739

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] In vivo gene transfer into newly-hatched chick brain by electroporation.2007

    • Author(s)
      Yamaguchi S., Katagiri S., Hirose N., Fujimoto Y., Mori M., Fujii-Taira I., Takano T., Matsushima T., Homma K.J.
    • Journal Title

      Neuro Report (in press)

    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] Involvement of ACSL in local synthesis of neutral lipids in cytoplasmic lipid droplets in human hepatocyte HuH72007

    • Author(s)
      Fujimoto Y., Itabe H., Kinoshita T., Homma K. J., Onoduka J., Mori M., Yamaguchi S., Makita M., Higashi Y., Yamashita A. and Takano T.
    • Journal Title

      J. Lipid Res 48(6)

      Pages: 1280-1292

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] Long-chain Fatty Acids Induce Lipid Droplet Formation in a Cultured Human Hepatocyte in a Manner Dependent of Acyl-CoA Synthetase.2006

    • Author(s)
      Fujimoto Y., Onoduka J., Homma K.J., Yamaguchi S., Mori M., Higashi Y., Makita M., Kinoshita T., Noda J., Itabe H., Takano T.
    • Journal Title

      Biol.Pharm.Bull 29

      Pages: 2174-2180

    • NAID

      110004840387

    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] Crystal structure of Vigna radiata cytokinin-specific binding potein in complex with zeatin.2006

    • Author(s)
      Pasternak O., Bujacz G.D., Fujimoto Y., Hashimoto Y., Jelen F., Otlewski J., Sikorski M., Jaskolski M.
    • Journal Title

      Plant Cell 18

      Pages: 1-13

    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] ADRP/adipophilin is degraded through the proteasome-dependent pathway during regression of lipid-storing cells.2006

    • Author(s)
      Masuda Y., Itabe H., Odaki M., Hama K., Fujimoto Y., Mori M., Sasabe N., Aoki J., Arai H., Takano T.(第一著者Masuda Y.)
    • Journal Title

      Journal of Lipid Research 47(1)

      Pages: 87-98

    • Data Source
      KAKENHI-PROJECT-15790049
  • [Journal Article] Crystal structure of Vigna radiata cytokinin-specific binding potein in complex with zeatin2006

    • Author(s)
      Pasternak O., Bujacz G. D., Fujimoto Y., Hashimoto Y., Jelen F., Otlewski J., Sikorski M.M., and Jaskolski M.
    • Journal Title

      Plant Cell 18

      Pages: 1-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] Long-chain Fatty Acids Induce Lipid Droplet Formation in a Cultured Human Hepatocyte in a Manner Dependent of Acyl-CoA Synthetase2006

    • Author(s)
      Fujimoto Y., Onoduka J., Homma K. J., Yamaguchi S., Mori M., Higashi Y., Makita M., Kinoshita T., Noda J., Itabe H., and Takano T.
    • Journal Title

      Biol. Pharm. Bull 29(11)

      Pages: 2174-2180

    • NAID

      110004840387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Journal Article] Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH72004

    • Author(s)
      Y.Fujimoto, T.Takano et al.
    • Journal Title

      Bioch.Bioph.Acta. 1644

      Pages: 47-59

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370751
  • [Journal Article] Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH72004

    • Author(s)
      Y.Fujimoto et al.
    • Journal Title

      Bioch. Bioph. Acta. 1644

      Pages: 47-59

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370751
  • [Journal Article] Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH72004

    • Author(s)
      Y.Fujimoto et al.
    • Journal Title

      Bioch.Bioph.Acta. 1644

      Pages: 47-59

    • Data Source
      KAKENHI-PROJECT-14370751
  • [Presentation] Escherichia coliATP合成酵素変異型cサブユニットの抑圧変異の解析2012

    • Author(s)
      高橋翔太、荒木信、藤本康之、前田正知
    • Organizer
      第51回日本薬学会東北支部大会
    • Place of Presentation
      青森市
    • Year and Date
      2012-10-07
    • Data Source
      KAKENHI-PROJECT-22590069
  • [Presentation] Lysosomal targeting of ABC transporter TAPL (Transporter Associated with Antigen Processing Like) 招待公演2011

    • Author(s)
      Maeda M. and Fujimoto Y.
    • Organizer
      BIT's 4th Annual Protein and Peptide Conference
    • Place of Presentation
      Beijing China
    • Year and Date
      2011-03-24
    • Data Source
      KAKENHI-PROJECT-22590069
  • [Presentation] Lysosomal targeting of ABC transporter TAPL (Transporter Associated with Antigen Processing Like)2011

    • Author(s)
      Maeda M., Fujimoto Y.
    • Organizer
      BIT's 4^<th> Annual Protein and Peptide Conference
    • Place of Presentation
      Beijing China(招待公演)
    • Year and Date
      2011-03-24
    • Data Source
      KAKENHI-PROJECT-22590069
  • [Presentation] ABC輸送体TAPL (ABCB9)のlysosome局在化におけるN末端領域膜貫通ドメインの寄与2011

    • Author(s)
      藤本康之、前田正知
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都市
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-22590069
  • [Presentation] ABC 輸送体 TAPL (ABCB9) のlysosome 局在化におけるN 末端領域膜貫通ドメインの寄与2011

    • Author(s)
      藤本康之、前田正知
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都市
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-22590069
  • [Presentation] ABC輸送体TAPL(ABCB9)のlysosome局在化におけるN末端領域の寄与2010

    • Author(s)
      藤本康之、前田正知
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22590069
  • [Presentation] ABC 輸送体 TAPL(ABCB9)の lysosome 局在化における N末端領域の寄与2010

    • Author(s)
      藤本康之、前田正知
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会
    • Place of Presentation
      神戸市
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22590069
  • [Presentation] 心筋細胞分化系におけるgata-4遺伝子の発現制御2008

    • Author(s)
      石橋拓也、大橋一晶、牛島弘雅、藤本康之、前田正知
    • Organizer
      第47回日本薬学会東北支部大会
    • Place of Presentation
      岩手医科大学薬学部
    • Year and Date
      2008-10-26
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Presentation] ABC輸送体TAPL(ABCB9)のlysosome局在2008

    • Author(s)
      藤本康之, 前田正知
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会 合同大会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Presentation] ABC輸送体TAPL(ABCB9)のlysosome局在2008

    • Author(s)
      藤本康之、前田正知
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Presentation] MAP2(Microtubule-Associated Protein 2)の遺伝子発現と鳥類記憶学習の相関2007

    • Author(s)
      松井隆剛、村上明男、山口真二、藤本康之、松島俊也、高野達哉、本間光一
    • Organizer
      日本薬学会第127年会
    • Place of Presentation
      富山国際会議場
    • Year and Date
      2007-03-28
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Presentation] In vivoエレクトロポレーション法を用いたニワトリ雛大脳領域への遺伝子導入2007

    • Author(s)
      片桐幸子、廣瀬直樹、山口真二、藤本康之、松島俊也、高野達哉、本間光一
    • Organizer
      日本薬学会第127年会
    • Place of Presentation
      富山国際会議場
    • Year and Date
      2007-03-28
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Presentation] ADIPOSE DIFFERENTIATION-RELATED PROTEIN(ADRP)IS A KEY COMPONENT OF LIPID STORAGE AND MOBILIZATION IN MACROPHAGE FOAM CELLS2006

    • Author(s)
      Itabe H., Masuda Y, Mori M., Fujimoto Y., Arai H. and Takano T.
    • Organizer
      20th IUBMB International Congress of Biochemistry and molecular Biology
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Presentation] PROTEASOME-DEPENDENT PATHWAY IS INVOLVED IN RAPID DEGRADATION OF ADIPOSE DIFFERENTIATION-RELATED PROTEIN DURING REGRESSION OF INTRACELLULAR LIPID DROPLETS2006

    • Author(s)
      Sasabe N., Takano T., Fujimoto Y., Itabe H., and Arai H.
    • Organizer
      20th IUBMB International Congress of Biochemistry and molecular Biology
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-18590072
  • [Presentation] Escherichia coli ATP合成酵素変異型cサブユニットの抑圧変異の解析

    • Author(s)
      高橋翔太,荒木信,藤本康之,前田正知
    • Organizer
      第51回 日本薬学会東北支部大会
    • Place of Presentation
      青森大学薬学部
    • Data Source
      KAKENHI-PROJECT-22590069
  • 1.  TAKANO Tatsuya (40124995)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 2.  MORI Masahiro (00230079)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  ITABE Hiroyuki (30203079)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  HIGASHI Yusuke (60286979)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  HOMMA Kouichi (90251438)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KIMURA Junji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  松田 譲
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  矢守 隆夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  小島 直人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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