GOTODA TAKANARI 後藤田貴也

… Alternative Names

後藤田貴也ゴトウダタカナリ

GOTODA Takanari 後藤田貴也

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Researcher Number	60322062
Affiliation (Current)	2025: 杏林大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2022: 杏林大学, 医学部, 教授 2004: The University of Tokyo, Faculty of Medicine, Visiting Associate Professor, 医学部附属病院, 客員助教授 2004: 東京大学, 医学部附属病院, 寄附講座教員 2001 – 2003: Tokyo Women's Medical University, Internal Medicine, Lecturer, 医学部, 講師 2001: Tokyo Women's Medical College, Diabetes Center, Associate, 糖尿病センター, 助手 2001: 東京女子医科大学, 糖尿病センター, 助手 2000: University of Tokyo, Facoolty of Medicin Assistant Professor, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Metabolomics / Biological Sciences / Basic Section 54040:Metabolism and endocrinology-related / Metabolomics Except Principal Investigator Metabolomics
Keywords	Principal Investigator 遺伝子 / SHR / メタボリックシンドローム / キヌレニン / ビタミンE / QTL / SLC / 内臓脂肪蓄積 / ビリルビン / トランスポーター … More / 脂肪蓄積 / ラット / インスリン抵抗性 / 高血圧 / KAT / グルコキナーゼ / ノックアウトマウス / 糖代謝 / キヌレン酸 / クロロキン / メタボローム / complication / diabetes / vitamine E / 血管合併症 / 合併症 / 糖尿病 / Chromosome 9 / Gene / Animal model / Insulin resistance / QTL解析 / 9番染色体 / モデル動物 / アデノウイルスベクター / 延髄腹外側野 / 膵臓癌 / 発がん / がん / トコフェロール … More Except Principal Investigator ACAT / ジーンターゲティング / コレステロール / ホルモン感受性リパーゼ / hormone-sensitive lipase / adenovirus / gene targeting / atherosclerosis / コレステロールエステル / アデノウイルス / 遺伝子治療 / マクロファージ / 泡沫細胞 / アデノウィルス / 動脈硬化 / catecholamoine / Free fatty acids / Infertility / Cholesterol / Triacylglycerol / Hormone-sensitive lipase / Adipocytes / Obesity / ノックアウトマウス / リパーゼ / 糖尿病 / カテコラミン / 遊離脂肪酸 / トリグリセリド / 不妊 / 脂肪細胞 / 肥満 Less

Investigation of regulatory mechanisms for glucose metabolism through metabolic pathway of kynurenic acidPrincipal Investigator
- Principal Investigator
  
  Gotoda Takanari
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kyorin University
A search for molecules that regulate the function of Slc22a18, an orphan transporter associated genetically with fat accumulationPrincipal Investigator
- Principal Investigator
  
  GOTODA TAKANARI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kyorin University
Investigation of the physiological function of Slc22a18, a candidate identified by a genetic analysis on animal models for visceral fat accumulationPrincipal Investigator
- Principal Investigator
  
  GOTODA TAKANARI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kyorin University
Analysis of possible association between α-tocopherol transfer protein gene and diabetes mellitus or its clinical complications.Principal Investigator
- Principal Investigator
  
  GOTODA Takanari
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
  Tokyo Women's Medical University
高血圧自然発症ラットの原因候補遺伝子KAT-1の解析とヒト疾患との関連の検討Principal Investigator
- Principal Investigator
  
  後藤田貴也
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Women's Medical University
ビタミンE転送蛋白質遺伝子と発がんリスクの個体差に関する分子疫学的研究Principal Investigator
- Principal Investigator
  
  後藤田貴也
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Women's Medical University
ビタミンE転送蛋白質遺伝子と発ガンリスクの個体差に関する分子疫学的研究Principal Investigator
- Principal Investigator
  
  後藤田貴也
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Genetic analysis of the molecular basis of insulin resistance both in animal models and in humans.Principal Investigator
- Principal Investigator
  
  GOTODA Takanari
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Tokyo Woman's Medical University
  The University of Tokyo
New therapeutic targets for atherosclerotic plaques - The role of acyl CoA : cholesterol acyltransferase and neutral cholesterol ester hydrolase in foam cell formation
- Principal Investigator
  
  ISHIBASHI Shun
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Transgenic study on the heterogeneity of intacellular triacylglycerol lipase
- Principal Investigator
  
  ISHIBASHI Shun
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Metabolomics
- Research Institution
  University of Tokyo

All 2021 2020 2019 2018 2017 2016 2015 2014 2004 2003 Other

All Journal Article Presentation Other

[Journal Article] Current Diagnosis and Management of Primary Chylomicronemia2021
- Author(s)
  Okazaki Hiroaki、Gotoda Takanari、Ogura Masatsune、Ishibashi Shun、Inagaki Kyoko、Daida Hiroyuki、Hayashi Toshio、Hori Mika、Masuda Daisaku、Matsuki Kota、Yokoyama Shinji、Harada-Shiba Mariko
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 28 Issue: 9 Pages: 883-904
- DOI
  10.5551/jat.RV17054
- NAID
  130008082103
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2021-09-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21595, KAKENHI-PROJECT-20K08871, KAKENHI-PROJECT-21K08143, KAKENHI-PROJECT-23K21443
[Journal Article] Polygenic Architecture of Common Severe Hypertriglyceridemia2020
- Author(s)
  Takashi Yamamoto, Takanari Gotoda
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 27 Issue: 12 Pages: 1255-1256
- DOI
  10.5551/jat.ED133
- NAID
  130007948664
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2020-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08871
[Journal Article] Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency2019
- Author(s)
  Takanashi M, Kimura T, Li C, Tanaka M, Matsuhashi A, Yoshida H, Noda A, Xu P, Takase S, Okazaki S, Iizuka Y, Kumagai H, Ikeda Y, Gotoda T, Takahashi M, Yagyu H, Ishibashi S, Yamauchi T, Kadowaki T, Liang G, Okazaki H.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 39 Issue: 3 Pages: 373-386
- DOI
  10.1161/atvbaha.118.311931
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08585, KAKENHI-PROJECT-17K09858, KAKENHI-PROJECT-18K08504, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-17K09867, KAKENHI-PROJECT-26000012
[Journal Article] KLF15 Enables Rapid Switching between Lipogenesis and Gluconeogenesis during Fasting.2016
- Author(s)
  Takeuchi Y, Yahagi N, Aita Y, Murayama Y, Sawada Y, Piao X, Toya N, Oya Y, Shikama A, Takarada A, Masuda Y, Nishi M, Kubota M, Izumida Y, Yamamoto T, Sekiya M, Matsuzaka T, Nakagawa Y, Urayama O, Kawakami Y, Iizuka Y, Gotoda T, Itaka K, Kataoka K, Nagai R, Kadowaki T, Yamada N, Lu Y, Jain MK, and Shimano H
- Journal Title
  
  Cell Rep.
  
  Volume: 16 Issue: 9 Pages: 2373-2386
- DOI
  10.1016/j.celrep.2016.07.069
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-WRAPUP-16H01688, KAKENHI-PROJECT-15H02541, KAKENHI-PROJECT-15H03092, KAKENHI-PROJECT-15H03093, KAKENHI-PROJECT-15H04824, KAKENHI-PROJECT-26461357, KAKENHI-PROJECT-16K13040
[Journal Article] p53 involvement in the pathogenesis of fatty liver disease.2004
- Author(s)
  Yahagi N., Gotoda T., et al.
- Journal Title
  
  J.Biol.Chem 279
  
  Pages: 20571-20575
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590956
[Journal Article] Mutations in Japanese subjects with primary hyperlipidemia.2004
- Author(s)
  Maruyama T, Gotoda T. et al.
- Journal Title
  
  J Atheroscler Thromb 11
  
  Pages: 131-145
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590956
[Journal Article] p53 involvement in the pathogenesis of fatty liver.2004
- Author(s)
  N.Yahagi, T.Gotoda, et al.
- Journal Title
  
  J.Biol Chem 279
  
  Pages: 20571-20575
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590956
[Journal Article] Mutations in Japanese subjects with primary hyperlipidemia.2004
- Author(s)
  Maruyama T, Gotoda T., et al.
- Journal Title
  
  J Atheroscler Thromb 11
  
  Pages: 131-145
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590956
[Journal Article] p57Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleus.2003
- Author(s)
  T.Yokoo, T.Gotoda, et al.
- Journal Title
  
  J Biol Chem 278
  
  Pages: 52919-52923
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590956
[Journal Article] Binge eating as a phenotype of melanocortin4 receptor gene mutations.2003
- Author(s)
  T.Gotoda
- Journal Title
  
  N Engl J Med 349
  
  Pages: 606-606
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590956
[Journal Article] p57Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleus.2003
- Author(s)
  Yokoo T., Gotoda T., et al.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 52919-52923
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590956
[Journal Article] Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase gene.2003
- Author(s)
  Ohashi K., Gotoda T., et al.
- Journal Title
  
  J.Biol.Chem. 278
  
  Pages: 42936-42941
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590956
[Journal Article] Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl CoA reductase gene.2003
- Author(s)
  K.Ohashi, T.Gotoda, et al.
- Journal Title
  
  J Biol Chem 278
  
  Pages: 42936-42941
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590956
[Journal Article] Binge eating as a phenotype of melanocortin 4 receptor gene mutations.2003
- Author(s)
  Gotoda T
- Journal Title
  
  N.Engl.J.Med. 349
  
  Pages: 606-606
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590956
[Presentation] キヌレン酸代謝系の介入による糖代謝制御機構の解析.2020
- Author(s)
  山本隆史、後藤田貴也
- Organizer
  第52回日本動脈硬化学会総会・学術集会.
- Data Source
  KAKENHI-PROJECT-20K08871
[Presentation] Genetic intervention in kynurenine pathway alters glucose metabolism in mice.2019
- Author(s)
  Takashi Yamamoto, Takanari Gotoda
- Organizer
  The 79th Scientific Sessions, American Diabetes Association (ADA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09867
[Presentation] 栄養・代謝とエイジング2019
- Author(s)
  後藤田貴也
- Organizer
  第14回日本アンチエイジング歯科学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09867
[Presentation] キヌレン酸代謝系が糖代謝制御に及ぼす影響2018
- Author(s)
  山本隆史、飯塚陽子、藤田敏郎、後藤田貴也
- Organizer
  第55回日本臨床分子医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09867
[Presentation] キヌレン酸代謝系介入による糖代謝制御に及ぼす影響2018
- Author(s)
  山本隆史、飯塚陽子、藤田敏郎、後藤田貴也
- Organizer
  第50回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K09867
[Presentation] メタボリックシンドローム関連遺伝子KAT-1（kynurenine aminotransferase-1）の糖代謝に及ぼす影響2017
- Author(s)
  山本隆史，飯塚陽子，藤田敏郎，後藤田貴也
- Organizer
  第49回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K09867
[Presentation] メタボリックシンドローム関連遺伝子KAT-1（kynurenine aminotransferase-1）の糖代謝に及ぼす影響2016
- Author(s)
  山本隆史、飯塚陽子、藤田敏郎、後藤田貴也
- Organizer
  第48回日本動脈硬化学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-26461357
[Presentation] SHRの遺伝解析により同定された内臓脂肪蓄積関連遺伝子Slc22a18の生理的機能の解析2015
- Author(s)
  山本隆史、　後藤田貴也
- Organizer
  第88回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26461357
[Presentation] SHRの遺伝解析により同定された内臓脂肪蓄積関連遺伝子Slc22a18の生理的機能の解析2015
- Author(s)
  山本隆史、　飯塚陽子、　藤田敏郎、　後藤田貴也
- Organizer
  第47回日本動脈硬化学会総会・学術集会
- Place of Presentation
  仙台
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-26461357
[Presentation] 高血圧自然発症ラット(SHR)の遺伝解析から同定された内臓脂肪蓄積関連遺伝子Slc22a18の発現調節機構および肝脂肪蓄積への関与の解明2014
- Author(s)
  後藤田　貴也、　山本　隆史
- Organizer
  第87回日本生化学会
- Place of Presentation
  京都
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-26461357
[]

1. ISHIBASHI Shun (90212919)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. SHIMANO Hitoshi (20251241)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. KUSAKA Takako (20338974)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. OSUGA Jun-ichi (10334400)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YAMADA Nobuhiro (40200729)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 山本隆史 (00572033)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. HARADA Kenji

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. OHASHI Ken

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. IWAMOTO Yasuhiko (60143434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 手納信一 (00307498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 太田陽子 (00338972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 熊谷英敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 池田祐一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

GOTODA TAKANARI 後藤田 貴也

後藤田 貴也 ゴトウダ タカナリ

GOTODA Takanari 後藤田 貴也

Research Projects

Research Products

Co-Researchers

Investigation of regulatory mechanisms for glucose metabolism through metabolic pathway of kynurenic acidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A search for molecules that regulate the function of Slc22a18, an orphan transporter associated genetically with fat accumulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of the physiological function of Slc22a18, a candidate identified by a genetic analysis on animal models for visceral fat accumulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of possible association between α-tocopherol transfer protein gene and diabetes mellitus or its clinical complications.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

高血圧自然発症ラットの原因候補遺伝子KAT-1の解析とヒト疾患との関連の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ビタミンE転送蛋白質遺伝子と発がんリスクの個体差に関する分子疫学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ビタミンE転送蛋白質遺伝子と発ガンリスクの個体差に関する分子疫学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genetic analysis of the molecular basis of insulin resistance both in animal models and in humans.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New therapeutic targets for atherosclerotic plaques - The role of acyl CoA : cholesterol acyltransferase and neutral cholesterol ester hydrolase in foam cell formation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Transgenic study on the heterogeneity of intacellular triacylglycerol lipase

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Current Diagnosis and Management of Primary Chylomicronemia2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Polygenic Architecture of Common Severe Hypertriglyceridemia2020

Author(s)

Journal Title

DOI

NAID

GOTODA TAKANARI 後藤田貴也

後藤田貴也ゴトウダタカナリ

GOTODA Takanari 後藤田貴也