IMBE Hiroki 井辺弘樹

Researcher Number	60326353
Other IDs
Affiliation (Current)	2025: 和歌山県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2006 – 2024: 和歌山県立医科大学, 医学部, 講師 2002 – 2003: 和歌山県立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Pain science / Basic Section 55050:Anesthesiology-related / Pain science / 疼痛学 Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Nerve anatomy/Neuropathology
Keywords	Principal Investigator 下行性疼痛調節系 / 疼痛学 / ストレス / 運動療法 / 痛覚過敏 / エピジェネティクス / アセチルコリン / ストレス性痛覚過敏 / 内側視索前野 / ストレス性疼痛過敏 … More / 神経科学 / Pain / Signal transduction / シグナル伝達 / 下行性疼痛 / 下行正疼痛調節系 … More Except Principal Investigator DRG / TROY / BDNF / FK506 / 疼痛緩和調節系 / 痛覚過敏 / アロマセラピー / 水蒸気蒸留法 / 痛覚過敏緩和効果 / サンショウアロマ成分 / 5-HT / hippocampus / stress / galectin-1 / LIF / 神経幹細胞 / Galectin-1 / 細胞内カルシウム / セロトニン / 海馬 / ストレス / ガレクチン-1 / 後根神経節 Less

stress-induced pain enhancement and exercise therapy -involvement of the cholinergic system in the rostral ventromedial medullaPrincipal Investigator
- Principal Investigator
  
  井辺弘樹
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Wakayama Medical University
山椒香気成分による痛覚過敏緩和効果: 嗅覚神経系と疼痛緩和調節系との接点解析
- Principal Investigator
  
  井原勇人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Wakayama Medical University
ストレスによる疼痛増強と運動療法－内側視索前野のエピジェネティクスの関与－Principal Investigator
- Principal Investigator
  
  井辺弘樹
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Wakayama Medical University
Stress-induced hyperalgesia : Functional changes in descending pain modulation system and involvement of epigeneticsPrincipal Investigator
- Principal Investigator
  
  Imbe Hiroki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Wakayama Medical University
Stress-induced enhancement of pain : neuroplastic changes of pain modulation system in the brainPrincipal Investigator
- Principal Investigator
  
  Imbe Hiroki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Wakayama Medical University
Elucidation of brain mechanism underlying stress-induced hyperalgesiaPrincipal Investigator
- Principal Investigator
  
  IMBE Hiroki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Wakayama Medical University
Functional change in descending pain modulatory system induced by chronic stressesPrincipal Investigator
- Principal Investigator
  
  IMBE Hiroki
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  疼痛学
- Research Institution
  Wakayama Medical University
The significance of MAPK activation in the descending pain modulatory system during peripheral inflammationPrincipal Investigator
- Principal Investigator
  
  IMBE Hiroki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Wakayama Medical University
Roles of cytokines and trophic factors on the plastic changes of dendritic morphology
- Principal Investigator
  
  SENBA Emiko
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Wakayama Medical University

[Book] Emphasizing histone-related chromatin remodeling in the central nervous system of animal models of chronic pain. In “Epigenetics of Chronic Pain”2018
- Author(s)
  Imbe H
- Total Pages
  234
- Publisher
  Academic Press publication
- ISBN
  9780128140703
- Data Source
  KAKENHI-PROJECT-17K09038
[Journal Article] Mu opioid receptor expressing neurons in the rostral ventromedial medulla are the source of mechanical hypersensitivity induced by repeated restraint stress2023
- Author(s)
  Imbe Hiroki、Ihara Hayato
- Journal Title
  
  Brain Research
  
  Volume: 1815 Pages: 148465-148465
- DOI
  10.1016/j.brainres.2023.148465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K10805
[Journal Article] Significance of medial preoptic area among the subcortical and cortical areas that are related to pain regulation in the rats with stress-induced hyperalgesia2020
- Author(s)
  Imbe H, Kimura A
- Journal Title
  
  Brain Res
  
  Volume: 1735 Pages: 146758-146758
- DOI
  10.1016/j.brainres.2020.146758
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09038
[Journal Article] Increase of histone acetylation in the GABAergic neurons in the rostral ventromedial medulla associated with mechanical hypersensitivity after repeated restraint stress2018
- Author(s)
  Imbe H, Kimura A
- Journal Title
  
  Brain Res Bull.
  
  Volume: 142 Pages: 394-402
- DOI
  10.1016/j.brainresbull.2018.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09038
[Journal Article] Attenuation of pCREB and Egr1 expression in the insular and anterior cingulate cortices associated with enhancement of CFA-evoked mechanical hypersensitivity after repeated forced swim stress.2017
- Author(s)
  Imbe H, Kimura A
- Journal Title
  
  Brain Res Bull.
  
  Volume: 134 Pages: 253-261
- DOI
  10.1016/j.brainresbull.2017.08.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09038
[Journal Article] Repeated forced swim stress affects the expression of pCREB and ΔFosB and the acetylation of histone H3 in the rostral ventromedial medulla and locus coeruleus.2016
- Author(s)
  Imbe H, Kimura A
- Journal Title
  
  Brain Res Bull.
  
  Volume: 127 Pages: 11-22
- DOI
  10.1016/j.brainresbull.2016.08.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460702
[Journal Article] Repeated forced swim stress prior to complete Freund's adjuvant injection enhances mechanical hyperalgesia and attenuates the expression of pCREB and ΔFosB and the acetylation of histone H3 in the insular cortex of rat.2015
- Author(s)
  Imbe H, Kimura A
- Journal Title
  
  Neuroscience
  
  Volume: 301 Pages: 12-25
- DOI
  10.1016/j.neuroscience.2015.05.065
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460702
[Journal Article] 下行性痛覚抑制系機能に及ぼすストレスの影響2015
- Author(s)
  井辺弘樹、木村晃久
- Journal Title
  
  ペインクリニック
  
  Volume: 36 Pages: 601-607
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460702
[Journal Article] ストレスによる下行性疼痛調節系の機能変化2015
- Author(s)
  井辺弘樹、木村晃久
- Journal Title
  
  日本運動器疼痛学会誌
  
  Volume: 7 Pages: 7-14
- NAID
  40020467362
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460702
[Journal Article] Repeated forced swim stress enhances CFA-evoked thermal hyperalgesia and affects the expressions of pCREB and c-Fos in the insular cortex.2014
- Author(s)
  Imbe H, Kimura A, Donishi T, Kaneoke Y
- Journal Title
  
  Neuroscience
  
  Volume: 259 Pages: 1-11
- DOI
  10.1016/j.neuroscience.2013.11.045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590717, KAKENHI-PROJECT-24591303
[Journal Article] 下行性疼痛促進系2013
- Author(s)
  井辺弘樹、仙波恵美子
- Journal Title
  
  ペインクリニック
  
  Volume: 34 Pages: 1069-1077
- Data Source
  KAKENHI-PROJECT-23590717
[Journal Article] Effects of restraint stress on glial activity in the rostral ventromedial medulla.2013
- Author(s)
  Imbe H, Kimura A, Donishi T, Kaneoke Y
- Journal Title
  
  Neuroscience
  
  Volume: 241 Pages: 10-21
- DOI
  10.1016/j.neuroscience.2013.03.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590717
[Journal Article] Chronic restraint stress decreases glial fibrillary acidic protein and glutamate transporter in the periaqueductal gray matter.2012
- Author(s)
  Imbe H, Kimura A, Donishi T, Kaneoke Y
- Journal Title
  
  Neuroscience
  
  Volume: 223 Pages: 209-218
- DOI
  10.1016/j.neuroscience.2012.08.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590717
[Journal Article] Activation of Mitogen-Activated Protein Kinase in Descending Pain Modulatory System2011
- Author(s)
  Imbe, H. Senba E. Kimura A, Donishi T, Yokoi I, Kaneoke Y.
- Journal Title
  
  J Signal Transduct
  
  Volume: 2011 Pages: 10-10
- DOI
  10.1155/2011/468061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20602005, KAKENHI-PROJECT-21600011
[Journal Article] Activation of Mitogen-Activated Protein Kinase in Descending Pain Modulatory System.2011
- Author(s)
  Imbe,H.Senba E.Kimura A, Donishi T, Yokoi I, Kaneoke Y.
- Journal Title
  
  J Signal Transduct. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20602005
[Journal Article] Involvement of descending facilitation from the rostral ventromedial medulla in the enhancement of formalin-evoked nocifensive behavior following repeated forced swim stress2010
- Author(s)
  Imbe H. Okamoto K. Donishi T. Senba E. Kimura A.
- Journal Title
  
  Brain Res
  
  Volume: 1329 Pages: 103-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20602005
[Journal Article] Involvement of descending facilitation from the rostral ventromedial medulla in the enhancement of formalin-evoked nocifensive behavior following repeated forced swim stress2010
- Author(s)
  Imbe, et al.
- Journal Title
  
  Brain Research
  
  Volume: 1329 Pages: 103-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20602005
[Journal Article] Involvement of descending facilitation from the rostral ventromedial medulla in the enhancement of formalin-evoked nocifensive behavior following repeated forced swim stress.2010
- Author(s)
  Imbe H.Okamoto K.Donishi T.Senba E.Kimura A.
- Journal Title
  
  Brain Res 1329
  
  Pages: 103-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20602005
[Journal Article] Involvement of descending facilitation from the rostral ventromedial medulla in the enhancement of formalin-evoked nocifensive behavior following repeated forced swim stress2010
- Author(s)
  Imbe, et al.
- Journal Title
  
  Brain Research (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20602005
[Journal Article] Activation of ERK in the locus coeruleus following acute noxious stimulation2009
- Author(s)
  Imbe, et al.
- Journal Title
  
  Brain Research 1263
  
  Pages: 50-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20602005
[Journal Article] Activation of ERK in the rostral ventromedial medulla is involved in hyperalgesia during peripheral inflammation2008
- Author(s)
  Imbe, et. al.
- Journal Title
  
  Brain Research 1187
  
  Pages: 103-110
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613021
[Journal Article] Activation of ERK in the rostral ventromedial medulla is involved inhyperalgesia during peripheral inflammation.2008
- Author(s)
  Imbe, et. al.
- Journal Title
  
  Brain Research 1187
  
  Pages: 103-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613021
[Journal Article] 慢性痛における下行性疼痛調節系と5-HTの役割2007
- Author(s)
  井辺弘樹, ほか
- Journal Title
  
  医学のあゆみ 223
  
  Pages: 695-699
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Journal Article] Effects of peripheral inflammation on activation of p38 mitogen-activated protein kinase in the rostral ventromedial medulla2007
- Author(s)
  Imbe, et. al.
- Journal Title
  
  Brain Research 1134
  
  Pages: 131-139
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Journal Article] Effects of peripheral inflammation on activation of p38 mitogen-activ ated protein kinase in the rostral ventromedial medulla2007
- Author(s)
  Imbe, et. al.
- Journal Title
  
  Brain Research 1134
  
  Pages: 131-139
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613021
[Journal Article] The role of descending pain modulatory system in chronic pain state : with special reference to serotonergic neurons in the RVM2007
- Author(s)
  Imbe, et. al.
- Journal Title
  
  Journal of Clinical and Experimental Medicine(IGAKU NO AYUMI) 223
  
  Pages: 695-699
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Journal Article] Effects of peripheral inflammation on activation of p38 mitogen-activated protein kinase in the rostral ventromedial medulla2007
- Author(s)
  Imbe et al.
- Journal Title
  
  Brain Research 1134
  
  Pages: 131-139
- Data Source
  KAKENHI-PROJECT-18613021
[Journal Article] 慢性痛における下行性疼痛調節系と5-HTの役割.2007
- Author(s)
  井辺弘樹, ほか
- Journal Title
  
  医学のあゆみ 223
  
  Pages: 695-699
- Data Source
  KAKENHI-PROJECT-18613021
[Journal Article] Stress-induced hyperalgesia:animal models and putative mechanisms2006
- Author(s)
  Imbe, et. al.
- Journal Title
  
  Front Biosci 11
  
  Pages: 2179-92
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613021
[Journal Article] Stress-induced hyperalgesia : animal models and putative mechanisms.2006
- Author(s)
  Imbe, et. al.
- Journal Title
  
  Front Biosci 11
  
  Pages: 2179-2192
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Journal Article] Stress-induced hyperalgesia : animal models and putative mechanisms2006
- Author(s)
  Imbe et al.
- Journal Title
  
  Frontiers in Bioscience 11
  
  Pages: 2179-2192
- Data Source
  KAKENHI-PROJECT-18613021
[Presentation] Voluntary wheel running alleviates and prevents mechanical hypersensitivity induced by vertical chronic restraint stress（垂直型慢性拘束ストレスによる痛覚過敏の自発運動による緩和と予防）2023
- Author(s)
  廣野守俊、井原勇人、上勝也、中田正範、井辺弘樹
- Organizer
  日本薬理学会
- Data Source
  KAKENHI-PROJECT-23K10805
[Presentation] Voluntary wheel running both alleviates and prevents mechanical hypersensitivity induced by vertical chronic restraint stress, and increases pCREB expression in the RVM2023
- Author(s)
  井辺弘樹、井原勇人、上勝也、中田正範、廣野守俊
- Organizer
  神経科学会
- Data Source
  KAKENHI-PROJECT-23K10805
[Presentation] ストレス性痛覚過敏を生じたラットの下行性疼痛調節系における pCREB と MOR 発現の増加2022
- Author(s)
  井辺弘樹、木村晃久
- Organizer
  第45回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K08975
[Presentation] ストレス性痛覚過敏と下行性疼痛調節系の関与2021
- Author(s)
  井辺弘樹
- Organizer
  第26回日本口腔顔面痛学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09038
[Presentation] Repeated restraint stress induces mechanical hypersensitivity and affects the expression of MeCP2 and methylation of DNA in the rostral ventromedial medulla2021
- Author(s)
  Hiroki Imbe、 Akihisa Kimura
- Organizer
  第44回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08975
[Presentation] ストレス性痛覚過敏と下行性疼痛調節系の関与2021
- Author(s)
  井辺弘樹
- Organizer
  第26回日本口腔顔面痛学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08975
[Presentation] Repeated restraint stress induces mechanical hypersensitivity and affects the expression of MeCP2 and methylation of DNA in the rostral ventromedial medulla2021
- Author(s)
  Hiroki Imbe、 Akihisa Kimura
- Organizer
  第44回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09038
[Presentation] Significance of medial preoptic area among the subcortical and cortical areas that are related to pain regulation in the rats with stress-induced hyperalgesia2020
- Author(s)
  Hiroki Imbe, Akihisa Kimula
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K09038
[Presentation] Increase of histone acetylation in the RVM in the rat with stress-induced hyperalgesia2019
- Author(s)
  Hiroki Imbe, Akihisa Kimula
- Organizer
  9th FAOPS congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09038
[Presentation] 慢性ストレス後の機械的痛覚過敏に関連したRVM GABA ニューロンにおけるヒストンアセチル化の増加2019
- Author(s)
  井辺弘樹、木村晃久
- Organizer
  第２回日本心身医学関連学会合同集会
- Data Source
  KAKENHI-PROJECT-17K09038
[Presentation] Increase of histone acetylation in the RVM GABAergic neurons associated with mechanical hypersensitivity after repeated restraint stress2019
- Author(s)
  Hiroki Imbe, Akihisa Kimula
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K09038
[Presentation] 繰り返し強制水泳ストレス後の CFA による機械的感覚過敏の増強に関連した島および前帯状皮質における pCREB と Egr-1 発現の減弱2018
- Author(s)
  井辺弘樹、木村晃久
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K09038
[Presentation] 慢性拘束ストレスによる吻側延髄腹内側部におけるヒストン H3 アセチル化の増加2018
- Author(s)
  井辺弘樹、木村晃久
- Organizer
  第 111 回近畿生理学談話会
- Data Source
  KAKENHI-PROJECT-17K09038
[Presentation] Enhancement of inflammatory hyperalgesia and attenuation of transcription factor expression in the insular and anterior cingulate cortices after repeated forced swim stress2018
- Author(s)
  Hiroki Imbe, Akihisa Kimula
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K09038
[Presentation] Enhancement of inflammatory hyperalgesia and changes of neuroplasticity in descending pain modulation system after repeated forced swim stress2017
- Author(s)
  Hiroki Imbe, Akihisa Kimula
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K09038
[Presentation] 繰り返し強制水泳ストレスによる炎症性感覚過敏の増強と島皮質および前帯状皮質における pCREB、Egr-1の発現変化2017
- Author(s)
  井辺弘樹、木村晃久
- Organizer
  第 110 回近畿生理学談話会
- Data Source
  KAKENHI-PROJECT-17K09038
[Presentation] Repeated forced swim stress enhances CFA evoked hyperalgesia and affects the expression of transcription factor and the acetylation of histone H3 in the insular cortex.2016
- Author(s)
  IMBE H, KIMURA A
- Organizer
  16th World congress on pain
- Place of Presentation
  Yokohama. Japan.
- Year and Date
  2016-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460702
[Presentation] Repeated forced swim stress enhances CFA-evoked mechanical hypersensitivity and affects the expression of delta-FosB and acetylation of histone H3 in the rostral ventromedial medulla2016
- Author(s)
  Hiroki Imbe, Akihisa Kimura
- Organizer
  第 93 回日本生理学会大会
- Place of Presentation
  札幌市
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-26460702
[Presentation] 炎症性感覚過敏と島皮質における pCREB, acetylated histone H3, ΔFosB の発現に対する強制水泳ストレスの影響2016
- Author(s)
  井辺弘樹、木村晃久
- Organizer
  第 38 回日本疼痛学会
- Place of Presentation
  札幌市
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-26460702
[Presentation] 痛みと下行性疼痛調節系：ストレスによる可塑的変化2016
- Author(s)
  井辺弘樹
- Organizer
  第45回日本脊椎脊髄病学会
- Place of Presentation
  千葉市
- Year and Date
  2016-04-14
- Invited
- Data Source
  KAKENHI-PROJECT-26460702
[Presentation] 繰り返し強制水泳ストレスは炎症性感覚過敏を増強し、吻側延髄腹内側部や青斑核における最初期遺伝子の発現および histone H3アセチル化に影響を及ぼす2016
- Author(s)
  井辺弘樹、木村晃久
- Organizer
  第 109 回近畿生理学談話会
- Place of Presentation
  大阪市
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-26460702
[Presentation] 繰り返し強制水泳ストレスによる炎症性感覚過敏の増強と島皮質における pCREB、delta-FosB の発現変化2015
- Author(s)
  井辺弘樹、木村晃久
- Organizer
  第 108 回近畿生理学談話会
- Place of Presentation
  東大阪市
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-26460702
[Presentation] Repeated forced swim stress enhances CFA-evoked mechanical hypersensitivity and affects the expressions of pCREB and delta-FosB and the acetylation of histone H3 in the insular cortex2015
- Author(s)
  Hiroki Imbe, Akihisa Kimura
- Organizer
  第９２回日本生理学会大会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-23
- Data Source
  KAKENHI-PROJECT-26460702
[Presentation] Repeated forced swim stress enhances CFA-evoked thermal hyperalgesia and affects the expressions of pCREB and c-Fos in the insular cortex2015
- Author(s)
  Hiroki Imbe, Akihisa Kimura
- Organizer
  第 38 回日本神経科学大会
- Place of Presentation
  神戸市
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26460702
[Presentation] 吻側延髄腹内側部のグリア活性における拘束ストレスの影響2014
- Author(s)
  井辺弘樹、木村晃久
- Organizer
  第３６回日本疼痛学会
- Place of Presentation
  大阪市
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PROJECT-26460702
[Presentation] ストレスによる下行性疼痛調節系の機能変化2014
- Author(s)
  井辺弘樹
- Organizer
  第７回日本運動器疼痛学会
- Place of Presentation
  宇部市
- Year and Date
  2014-10-25
- Invited
- Data Source
  KAKENHI-PROJECT-26460702
[Presentation] 慢性拘束ストレス後の中脳中心灰白質におけるGFPA およびglutamate taransporter の減少2012
- Author(s)
  井辺弘樹、木村晃久、堂西倫弘、金桶吉起
- Organizer
  第105回近畿生理学談話会
- Place of Presentation
  守口
- Data Source
  KAKENHI-PROJECT-23590717
[Presentation] 慢性拘束ストレスによる中脳中心灰白質におけるGFAPおよびグルタメートトランスポーターの減少2012
- Author(s)
  井辺弘樹、木村晃久、堂西倫弘、金桶吉起
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590717
[Presentation] 慢性拘束ストレス後の下行性疼痛調節系におけるGFAPの減少2011
- Author(s)
  井辺弘樹、木村晃久、堂西倫弘、金桶吉起
- Organizer
  第104回近畿生理学談話会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-23590717
[Presentation] Chronic restraint stress decreases glial fibrillary acidic protein in the periaqueductal gray.2011
- Author(s)
  Imbe H, Kimura A, Donishi T, Kaneoke Y
- Organizer
  41th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-23590717
[Presentation] 慢性拘束ストレスは吻側延髄腹内側部においてGAP43蛋白質分解フラグメントを増加する.2010
- Author(s)
  Imbe H, Donishi T, Senba E, Kimura A.
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] シンポジウムストレスによる痛覚過敏のメカニズム-下行性疼痛調節系の関与2010
- Author(s)
  仙波恵美子、井辺弘樹
- Organizer
  Neuro2010(第33回日本神経科学大会)
- Place of Presentation
  神戸
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] ストレスによる痛覚過敏のメカニズム.下行性疼痛調節系の関与2010
- Author(s)
  仙波恵美子、井辺弘樹
- Organizer
  Neuro2010(第33回日本神経科学大会)
- Place of Presentation
  神戸
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] Involvement of descending facilitation from the rostral ventromedial medulla in the enhancement of formalin-evoked nocifensive behavior following repeated forced swim stress.2010
- Author(s)
  Hiroki Imbe, Akihisa Kimura, Tomohiro Donishi, Emiko Senba, Yoshiki Kaneoke.
- Organizer
  The 40th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] 慢性拘束ストレスは吻側延髄腹内側部においてGAP43蛋白質分解フラグメントを増加する2010
- Author(s)
  井辺弘樹、堂西倫弘、木村晃久
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] ストレスによる痛覚過敏のメカニズム.下行性疼痛調節系の関与.Neuro20102010
- Author(s)
  仙波恵美子、井辺弘樹.
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] Involvement of descending facilitation from the rostral ventromedial medulla in the enhancement of formalin-evoked nocifensive behavior following repeated forced swim stress2010
- Author(s)
  Hiroki Imbe, Akihisa Kimura, Tomohiro Donishi, Emiko Senba, Yoshiki Kaneoke
- Organizer
  The 40th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] Participation of descending facilitation from the rostral ventromedial medulla in repeated swim stress-induced hyperalgesia2009
- Author(s)
  Imbe H, Donishi T, Senba E, Kimura A.
- Organizer
  The 36th International Congress of Physiological Sciences(IUPS2009) July30
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] 強制水泳ストレス負荷後の疼痛反応増強における吻側延髄腹内側部の関与2009
- Author(s)
  井辺弘樹、仙波恵美子
- Organizer
  第31回日本疼痛学会
- Place of Presentation
  名古屋
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] 強制水泳ストレス負荷後の疼痛反応増強における吻側延髄腹内側部の関与.2009
- Author(s)
  井辺弘樹、仙波恵美子
- Organizer
  第31回日本疼痛学会
- Place of Presentation
  名古屋
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] コメディカルとともに痛みを学ぶワークショップ慢性ストレスにより痛みが増悪するメカニズムー下行性疼痛調節系の関与2009
- Author(s)
  仙波恵美子、井辺弘樹
- Organizer
  第31回日本疼痛学会
- Place of Presentation
  名古屋
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] Participation of descending facilitation from the rostral ventrome dial medulla in repeated swim stress-induced hyperalgesia2009
- Author(s)
  Imbe, et al.
- Organizer
  The 36th International Congress of Physiological Sciences(IUPS2009)
- Place of Presentation
  Kyoto
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] コメディカルとともに痛みを学ぶワークショップ慢性ストレスにより痛みが増悪するメカニズムー下行性疼痛調節系の関与.2009
- Author(s)
  仙波恵美子、井辺弘樹
- Organizer
  第31回日本疼痛学会
- Place of Presentation
  名古屋
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] Participation of descending facilitation from the rostral ventromedial medulla in repeated swim stress-induced hyperalgesia.2009
- Author(s)
  井辺弘樹, 堂西倫弘, 仙波恵美子, 木村晃久.
- Organizer
  The 36th International Congress of Physiological Sciences (IUPS2009)
- Place of Presentation
  Kyoto
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] Activation of ERK in the locus coeruleus induced by acute noxious stimulation.2008
- Author(s)
  Imbe H, et al.
- Organizer
  The 38th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Washington, DC. USA
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-20602005
[Presentation] Activation of ERK in the locus coeruleus induced by acute noxious stimulation2008
- Author(s)
  Imbe, et. al.
- Organizer
  The 85th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  Tokyo
- Year and Date
  2008-03-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Presentation] 急性侵害刺激による青斑核でのERK活性化2008
- Author(s)
  井辺弘樹, ほか
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京
- Year and Date
  2008-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Presentation] 炎症後の吻側延髄腹内側部におけるERK活性化は痛覚過敏に関与する2007
- Author(s)
  井辺弘樹, ほか
- Organizer
  第29回日本疼痛学会
- Place of Presentation
  横浜
- Year and Date
  2007-07-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Presentation] Effects of peripheral inflammation on activation of ERK and p38 MAPK in the rostral ventromedial medulla2007
- Author(s)
  Imbe, et. al.
- Organizer
  The 84th Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  Osaka
- Year and Date
  2007-03-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Presentation] 末梢組織炎症後の吻側延髄腹内側部におけるERKおよびp38MAPK活性化2007
- Author(s)
  井辺弘樹, ほか
- Organizer
  第84回日本生理学会大会
- Place of Presentation
  大阪
- Year and Date
  2007-03-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Presentation] 下行性疼痛調整系におけるMAPK活性化2007
- Author(s)
  井辺弘樹, ほか
- Organizer
  第81回千里神経懇話会
- Place of Presentation
  大阪
- Year and Date
  2007-03-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Presentation] Activation of MAPK in the descending pain modulatory system2007
- Author(s)
  Imbe, et. al.
- Organizer
  The 81th Meeting of the SENRI-SHINKEIKONWAKAI
- Place of Presentation
  Osaka
- Year and Date
  2007-03-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Presentation] Activation of ERK in the rostral ventromedial medulla is involved in hyperalgesia following peripheral inflammation2007
- Author(s)
  Imbe, et. al.
- Organizer
  The 29th Annual Meeting of the Japanese Association for the Study of Pain
- Place of Presentation
  Yokohama
- Year and Date
  2007-07-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Presentation] Activation of MAPK in the descending pain modulatory system2006
- Author(s)
  Imbe, et. al.
- Organizer
  The 2006 Meeting of the National Institute for Physiological Sciences
- Place of Presentation
  Okazaki
- Year and Date
  2006-11-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Presentation] 下行性疼痛調整系におけるMAPK活性化2006
- Author(s)
  井辺弘樹, ほか
- Organizer
  平成18年度生理学研究所研究会「痛みの分子メカニズムと治療戦略」
- Place of Presentation
  岡崎
- Year and Date
  2006-11-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18613021
[Presentation] 吻側延髄腹内側部のグリア活性における拘束ストレスの影響
- Author(s)
  井辺弘樹、木村晃久、堂西倫弘、金桶吉起
- Organizer
  第106回近畿生理学談話会
- Place of Presentation
  橿原市
- Data Source
  KAKENHI-PROJECT-23590717
[Presentation] Repeated forced swim stress enhances CFA-evoked thermal hyperalgesia and affects the expressions of pCREB and c-Fos in the insular cortex.
- Author(s)
  Hiroki Imbe, Akihisa Kimura, Tomohiro Donishi and Yoshiki Kaneoke
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島市
- Data Source
  KAKENHI-PROJECT-23590717
[Presentation] Chronic restraint stress decreases glial fibrillary acidic protein and glutamate transporter in the periaqueductal gray matter.
- Author(s)
  H. IMBE, A. KIMURA, T. DONISHI, Y. KANEOKE
- Organizer
  43th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23590717
[Presentation] 慢性拘束ストレス後の中脳中心灰白質におけるGFAPおよびglutamate transporterの減少
- Author(s)
  井辺弘樹
- Organizer
  第35回日本疼痛学会
- Place of Presentation
  さいたま市
- Data Source
  KAKENHI-PROJECT-23590717

1. KIMURA Akihisa (20225022)

# of Collaborated Projects: 4 results

# of Collaborated Products: 40 results
2. SENBA Emiko (00135691)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
3. 井原勇人 (00223298)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 廣野守俊 (30318836)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. MORIKAWA Yoshihiro (60230108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. AIKAWA Fumiko (60411427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 河合良訓 (80211861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IMBE Hiroki 井辺 弘樹

Research Projects

Research Products

Co-Researchers

stress-induced pain enhancement and exercise therapy -involvement of the cholinergic system in the rostral ventromedial medullaPrincipal Investigator

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山椒香気成分による痛覚過敏緩和効果: 嗅覚神経系と疼痛緩和調節系との接点解析

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ストレスによる疼痛増強と運動療法 － 内側視索前野のエピジェネティクスの関与 －Principal Investigator

Principal Investigator

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Stress-induced hyperalgesia : Functional changes in descending pain modulation system and involvement of epigeneticsPrincipal Investigator

Principal Investigator

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Stress-induced enhancement of pain : neuroplastic changes of pain modulation system in the brainPrincipal Investigator

Principal Investigator

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Elucidation of brain mechanism underlying stress-induced hyperalgesiaPrincipal Investigator

Principal Investigator

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Functional change in descending pain modulatory system induced by chronic stressesPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

The significance of MAPK activation in the descending pain modulatory system during peripheral inflammationPrincipal Investigator

Principal Investigator

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Research Institution

Roles of cytokines and trophic factors on the plastic changes of dendritic morphology

Principal Investigator

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Research Institution

[Book] Emphasizing histone-related chromatin remodeling in the central nervous system of animal models of chronic pain. In “Epigenetics of Chronic Pain”2018

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[Journal Article] Mu opioid receptor expressing neurons in the rostral ventromedial medulla are the source of mechanical hypersensitivity induced by repeated restraint stress2023

Author(s)

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[Journal Article] Significance of medial preoptic area among the subcortical and cortical areas that are related to pain regulation in the rats with stress-induced hyperalgesia2020

Author(s)

Journal Title

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[Journal Article] Increase of histone acetylation in the GABAergic neurons in the rostral ventromedial medulla associated with mechanical hypersensitivity after repeated restraint stress2018

Author(s)

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[Journal Article] Attenuation of pCREB and Egr1 expression in the insular and anterior cingulate cortices associated with enhancement of CFA-evoked mechanical hypersensitivity after repeated forced swim stress.2017

IMBE Hiroki 井辺弘樹

ストレスによる疼痛増強と運動療法－内側視索前野のエピジェネティクスの関与－Principal Investigator