Takeshita Fumihiko 武下文彦

… Alternative Names

TAKESHITA FUMIHIKO 武下文彦

KAKESHITA Humihiko

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Researcher Number	60333572
Other IDs
External Links
Affiliation (Current)	2025: 横浜市立大学, 医学研究科, 客員教授
Affiliation (based on the past Project Information) *help	2010: Yokohama City University, 医学研究科, 客員教授 2008 – 2009: Yokohama City University, 医学部, 准教授 2008: 横浜市立大学, 大学院・医学系研究科, 准教授 2007: Yokohama City University, Graduate School of Medicine, Assistant Professor 2007: Yokohama City University, Graduate School of Medicine, Associate Professor … More 2006 – 2007: Yokohama City University, Department of Molecular Biodefense Research, Associate professor, 分子生体防御学, 准教授 2006: 横浜市立大学, 分子生体防御学, 準教授 2006: Yokohama city university, School of medicine, Associate Professor, 医学部, 準教授 2005: 横浜市立大学, 分子生体防御学, 助手 2004 – 2005: 横浜市立大学, 医学部, 助手 2003: 国立感染症研究所, 病原微生物部, 研究員 Less
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Virology / Environmental pharmacy Except Principal Investigator Bacteriology (including Mycology) / Dermatology / Virology / Endocrinology / Immunology / Biological Sciences
Keywords	Principal Investigator 自然免疫 / ヒストン / 免疫調節薬 / 基礎医学 / 感染防御 / DNAワクチン / DNA vaccine / Histone / DNA virus infection / Innate immunity … More / double stranded DNA / 受容体 / シグナル伝達 / 感染免疫 / DNAウイルス感染 / 2本鎖DNA / ウイルス学 / 分子 / 遺伝子アジュバント / アジュバント … More Except Principal Investigator TLR / 自然免疫 / ワクチン / DNAワクチン / dsDNA / 鞭毛抗原 / TLR5 / 緑膿菌 / アジュバント / tributylzin / treatment / animal model / atopic dermatitis / CpG motif / 動物 / トリブチルスズ / 治療 / 動物モデル / アトピー性皮膚炎 / CpGモチーフ / GENE REGULATION / TRANSCRUPTION FACTOR / DNA VACCINE / 遺伝子発現 / 転写因子 / clinical investigation / type III secretion mechanism protein / flagella antigen / triple vaccine / DNA vaccine / Pseudomonas aeruginosa / natural immunity (TLR5 etc..) / 多価ワクチン / 臨床試験 / III型分泌機構蛋白質 / 三者混合ワクチン / 自然免疫(TLR5など) / Innate immunity / Autoimmunity / Infection / Thyroid / バセドウ病 / インターフェロン / サイログロブリン / MHC / ルシフェラーゼ / ホルモン合成 / ヨード / dsRNA / Toll様受容体 / B-DNA / 自己免疫 / 感染 / 甲状腺 / 抗原提示 / 樹状細胞 / DNA / SPR / QCM / 融合タンパク / 分子間相互作用 / センサー / 病原体 / 免疫学 / 感染症 / ウィルス / 遺伝子 Less

Development immunomodulative drug based on the recognition mechanism of viral B-DNA.Principal Investigator
- Principal Investigator
  
  TAKESHITA Fumihiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Yokohama City University
Elucidation of the mechanism underlying core histone-mediated antiviral innate immune responsePrincipal Investigator
- Principal Investigator
  
  TAKESHITA Fumihiko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Yokohama City University
Mechanism of nucleic ac id-based vaccine immunogenicity
- Principal Investigator
  
  ISHII Ken
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
新しい概念に基づく自然免疫・獲得免疫両面からの感染防御能の誘導
- Principal Investigator
  
  OKUDA Kenji
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yokohama City University
リコンビナントTLR融合蛋白を用いた病原体バイオセンサーの開発
- Principal Investigator
  
  SUZUKI Koichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  National Institute of Infectious Diseases
Research on molecular mechanisms of double stranded DNA-mediated innate immune activationPrincipal Investigator
- Principal Investigator
  
  TAKESHITA Fumihiko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yokohama City University
Novel Vaccines against Pseudomonas aeruginosa and Other Microorganisms
- Principal Investigator
  
  OKUDA Kenji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yokohama city university
DEVELOPMENT OF THE POSITIVE-FEEDBACK TRANSCRIPTIONAL/REGULATION SYSTEM FOR A DNA VACCINE VECTOR
- Principal Investigator
  
  SASAKI Shin
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  YOKOHAMA CITY UNIVERSITY SCHOOL OF MEDICINE
Treatment of atopic dermatitis with CpG oligodeoxynucleotide. Effects on skin lesions and cytokine priduction
- Principal Investigator
  
  AIHARA Michiko
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Yokohama City University
内因性自然免疫活性化分子を用いたDNAワクチンの免疫原性増幅法Principal Investigator
- Principal Investigator
  
  武下文彦
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Yokohama City University
インターフェロン反応性プロモータの開発とDNAワクチンへの応用
- Principal Investigator
  
  SASAKI Shin
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Infectious Diseases
Changes in gene expression profile and development of autoimmunity in the thyroid following infection.
- Principal Investigator
  
  SUZUKI Koichi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  National Institute of Infectious Diseases

All 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Patent

[Journal Article] Mutant mouse p53 transgene elevates the chemical induction of tumors that respond to gene silencing with siRNA.2010
- Author(s)
  Tanooka, H., K.Tatsumi, H.Tsuji, Y.Noda, T.Katsube, H.Ishii, A.Ootsuyama, F.Takeshita, T.Ochiya.
- Journal Title
  
  Cancer Gene Ther 17
  
  Pages: 1-10
- Data Source
  KAKENHI-PROJECT-20200074
[Journal Article] Extrachromosomal histone H2B mediates innate antiviral immune responses induced by intracellular double-stranded DNA.2010
- Author(s)
  Kobiyama, K., F. Takeshita, N. Jounai, A. Sakaue-Sawano, A. Miyawaki, K.J. Ishii, T. Kawai, S. Sasaki, H. Hirano, N. Ishii, K. Okuda, K. Suzuki
- Journal Title
  
  J Virol 84
  
  Pages: 822-832
- Data Source
  KAKENHI-PROJECT-20590477
[Journal Article] Extrachromosomal histone H2B mediates innate antiviral immune responses induced by intracellular double-stranded DNA.2010
- Author(s)
  Kobiyama, K., F.Takeshita, N.Jounai, A.Sakaue-Sawano, A.Miyawaki, K.J.Ishii, T.Kawai, S.Sasaki, H.Hirano, N.Ishii, K.Okuda, K.Suzuki.
- Journal Title
  
  J Virol 84
  
  Pages: 822-832
- Data Source
  KAKENHI-PROJECT-20200074
[Journal Article] Modulation of intracellular signaling using protein-transduction technology.2010
- Author(s)
  Kobiyama, K., N. Jounai, K.J. Ishii, T. Horii, K. Suzuki, A. Ryo, F. Takeshita
- Journal Title
  
  Crit Rev Immunol 30
  
  Pages: 395-421
- Data Source
  KAKENHI-PROJECT-20590477
[Journal Article] Immunogenicity of whole-parasite vaccines against Plasmodium falciparum involves malarial hemozoin and host TLR9.2010
- Author(s)
  Coban, C., Y. Igari, M. Yagi, T.Reimer, S.Koyama, T.Aoshi, K.Ohata, T.Tsukui, F.Takeshita, K.Sakurai, T.Ikegami, A.Nakagawa, T.Horii, G.Nunez, K.J.Ishii, S.Akira.
- Journal Title
  
  Cell Host Microbe 7
  
  Pages: 50-61
- Data Source
  KAKENHI-PROJECT-20200074
[Journal Article] Immunogenicity of whole-parasite vaccines against Plasmodium falciparum involves malarial hemozoin and host TLR9.2010
- Author(s)
  Coban, C., Y. Igari, M. Yagi, T. Reimer, S. Koyama, T. Aoshi, K. Ohata, T. Tsukui, F. Takeshita, K. Sakurai, T. Ikegami, A. Nakagawa, T. Horii, G. Nunez, K.J. Ishii, S. Akira
- Journal Title
  
  Cell Host Microbe 7
  
  Pages: 50-61
- Data Source
  KAKENHI-PROJECT-20590477
[Journal Article] Modulation of intracellular signaling using protein-transduction technology.2010
- Author(s)
  Kobiyama, K., N. Jounai, K.J.Ishii, T.Horii,K.Suzuki, A.Ryo, F.Takeshita.
- Journal Title
  
  Crit Rev Immunol 30
  
  Pages: 395-421
- Data Source
  KAKENHI-PROJECT-20200074
[Journal Article] Mutant mouse p53 transgene elevates the chemical induction of tumors that respond to gene silencing with siRNA.2010
- Author(s)
  Tanooka, H., K. Tatsumi, H. Tsuji, Y. Noda, T. Katsube, H. Ishii, A. Ootsuyama, F. Takeshita, T. Ochiya
- Journal Title
  
  Cancer Gene Ther 17
  
  Pages: 1-10
- Data Source
  KAKENHI-PROJECT-20590477
[Journal Article] Tryptophan aspartate-containing coat protein (CORO1A) suppresses Toll-like receptor signalling in Mycobacterium leprae infection.2009
- Author(s)
  Tanigawa, K., K.Suzuki, H.Kimura, F.Takeshita, H.Wu, T.Akama, A.Kawashima, N.Ishii.
- Journal Title
  
  Clin Exp Immunol 156
  
  Pages: 495-501
- Data Source
  KAKENHI-PROJECT-20200074
[Journal Article] A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine adjuvant.2009
- Author(s)
  Kobiyama, K., F. Takeshita, K. J. Ishii, S. Koyama, T. Aoshi, S. Akira, A. Sakaue-Sawano, A. Miyawaki, Y. Yamanaka, H. Hirano, K. Suzuki, K. Okuda
- Journal Title
  
  J Immunol 182
  
  Pages: 1593-1601
- Data Source
  KAKENHI-PROJECT-20590477
[Journal Article] Tryptophan aspartate-containing coat protein (CORO1A) suppresses Toll-like receptor signalling in Mycobacterium leprae infection.2009
- Author(s)
  Tanigawa, K., K. Suzuki, H. Kimura, F. Takeshita, H. Wu, T. Akama, A. Kawashima, N. Ishii
- Journal Title
  
  Clin Exp Immunol 156
  
  Pages: 495-501
- Data Source
  KAKENHI-PROJECT-20590477
[Journal Article] A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine adjuvant.2009
- Author(s)
  Kobiyama, K., F.Takeshita, K.J.Ishii, S.Koyama, T.Aoshi, S.Akira, A.Sakaue-Sawano, A.Miyawaki, Y.Yamanaka, H.Hirano, K.Suzuki, K.Okuda.
- Journal Title
  
  J Immunol 182
  
  Pages: 1593-1601
- Data Source
  KAKENHI-PROJECT-20200074
[Journal Article] A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine adjuvant.2009
- Author(s)
  Kobiyama K, Takeshita F*, Ishii KJ, Koyama S, Aoshi T, Akira S, Sakaue-Sawano A, Miyawaki A, Yamanaka Y, Hirano H, Suzuki K, Okuda K.
- Journal Title
  
  Journal of Immunology 182
  
  Pages: 1593-1601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590477
[Journal Article] A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine adjuvant2009
- Author(s)
  Kobiyama K, Takeshita F*, Ishii KJ, Koyama S, Aoshi T, Akira S, Sakaue-Sawano A, Miyawaki A, Yamanaka Y, Hirano H, Suzuki K, and Okuda K.
- Journal Title
  
  Journal of Immunology 182
  
  Pages: 1593-1601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200074
[Journal Article] Molecular and cellular mechanisms of DNA vaccines2008
- Author(s)
  Coban C, Koyama S, Takeshita F, Akira S, Ishii KJ.
- Journal Title
  
  Hum Vaccin 4(6)(Corresponding author)
- Data Source
  KAKENHI-PROJECT-19390139
[Journal Article] TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines2008
- Author(s)
  Ishii KJ, Kawagoe T, Koyama S, Matsui K, Kumar H, Kawai T, Uematsu S, Takeuchi O, Takeshita F, Coban C, Akira S.
- Journal Title
  
  Nature 451(7179)(Co-corresponding author)
  
  Pages: 725-9
- Data Source
  KAKENHI-PROJECT-19390139
[Journal Article] Molecular and cellular mechanisms of DNA vaccines.2008
- Author(s)
  Coban C, Koyama S, Takeshita F, Akira S, Ishii KJ*.
- Journal Title
  
  Hum Vaccine. 4(6).
  
  Pages: 453-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390139
[Journal Article] The non-canonical role of Atg family members as suppressors of innate antiviral immune signaling.2008
- Author(s)
  Takeshita F, Kobiyama K, Miyawaki A, Jounai N, and Okuda K.
- Journal Title
  
  Autophagy 4
  
  Pages: 1-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Intracellular DNA sensors in immunity.2008
- Author(s)
  F.Takeshita, K.J.Ishii.
- Journal Title
  
  Curr Opin Immunol 20
  
  Pages: 383-388
- Data Source
  KAKENHI-PROJECT-20200074
[Journal Article] The non-canonical role of Atg family members as suppressors of innate antiviral immune signaling2008
- Author(s)
  Takeshita F, Kobiyama K, Miyawaki A, Jounai N, and Okuda K.
- Journal Title
  
  Autophagy 4
  
  Pages: 1-4
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Intracellular DNA sensors in immunity2008
- Author(s)
  Takeshita F* and Ishii KJ.
- Journal Title
  
  Current Opinion in Immunology 20
  
  Pages: 383-388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200074
[Journal Article] The non-canonical role of Atg family members as suppressors of innate antiviral immune signaling.2008
- Author(s)
  Takeshita F, et. al.
- Journal Title
  
  Autophagy 4
  
  Pages: 1-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659111
[Journal Article] Intracellular DNA sensors in immunity2008
- Author(s)
  Takeshita F, Ishii KJ.
- Journal Title
  
  Curr Opin Immunol 20(4)(Corresponding author)
  
  Pages: 383-8
- Data Source
  KAKENHI-PROJECT-19390139
[Journal Article] Molecular and cellular mechanisms of DNA vaccines2008
- Author(s)
  Coban C, Koyama S, Takeshita F, Akira S, and Ishii KJ.
- Journal Title
  
  Human Vaccine 4
  
  Pages: 453-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200074
[Journal Article] Intracellular DNA sensors in immunity.2008
- Author(s)
  F. Takeshita, K. J. Ishii
- Journal Title
  
  Curr Opin Immunol 20
  
  Pages: 383-388
- Data Source
  KAKENHI-PROJECT-20590477
[Journal Article] Molecular and cellular mechanisms of DNA vaccines.2008
- Author(s)
  Coban, C., S. Koyama, F. Takeshita, S. Akira, K.J. Ishii
- Journal Title
  
  Hum Vaccin 4
  
  Pages: 453-456
- Data Source
  KAKENHI-PROJECT-20590477
[Journal Article] Intracellular DNA sensors in immunity2008
- Author(s)
  Takeshita F, Ishii KJ*
- Journal Title
  
  Curr Opin Immunol. 20(4)
  
  Pages: 383-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390139
[Journal Article] Molecular and cellular mechanisms of DNA vaccines.2008
- Author(s)
  Coban C, Koyama S, Takeshita F, Akira s, Ishii KJ.
- Journal Title
  
  Human Vaccine 4
  
  Pages: 453-456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590477
[Journal Article] The non-canonical role of Atg family members as suppressors of innate antiviral immune signaling2008
- Author(s)
  Takeshita, F., Kobiyama, K., Miyawaki ,A., Jounai, N., Okuda, K
- Journal Title
  
  Autophagy 4
  
  Pages: 1-4
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Tank-binding kinase-1 delineates innate and adaptive immune responses raised by DNA vaccines2008
- Author(s)
  Ishii, KJ., Kawagoe, T., Koyama, S., Matsui, K., Kumar, H., Kawai, T., Uematsu, S., Takeuchi, O., Takeshita, F., Coban, C., Akira, S
- Journal Title
  
  Nature 451
  
  Pages: 725-725
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Tank-binding kinase-1 delineates innate and adaptive immune responses raised by DNA vaccines.2008
- Author(s)
  Ishii KJ, Kawagoe T, Koyama S, Matsui K, Kumar H, Kawai T, Uematsu S, Takeuchi O, Takeshita F, Coban C, and Akira S.
- Journal Title
  
  Nature 451
  
  Pages: 725-728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Intracellular DNA sensors in immunity.2008
- Author(s)
  Takeshita F*, Ishii KJ.
- Journal Title
  
  Current Opinion in Immunology 20
  
  Pages: 383-388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590477
[Journal Article] Tank-binding kinase-I delineates innate and adaptive immune responses raised by DNA vaccines2008
- Author(s)
  Ishii KJ, Kawagoe T, Koyama S, Matsui K, Ktunar H, Kawai T, Uematsu S, Takeuchi O, Takeshita F, Coban C, and Akira S.
- Journal Title
  
  Nature 451
  
  Pages: 725-728
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Muscle creatine kinase/SV 40 hybrid promoter for muscle-targeted long-term transgene expression2007
- Author(s)
  Takeshita F, Takase K, Tozuka M, Saha S, Okuda K, Ishii N, Sasaki S
- Journal Title
  
  Int. J. Mol. Med. 19
  
  Pages: 309-315
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Suppression of iodide uptake and thyroid hormone synthesis with stimulation of the type I interferon system by double-stranded RNA(dsRNA)in cultured human thyroid follicles.2007
- Author(s)
  Yamazaki K, Suzuki K, Yamada E, Yamada T, Takeshita F, Matsumoto M, Mitsuhashi T, Obara T, Takano K and Sato K
- Journal Title
  
  Endocrinology 148
  
  Pages: 13226-3235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] The Atg5-Atg12 conjugate associates with innate antiviral immune responses2007
- Author(s)
  Jounai N, Takeshita F, Kobiyama K, Sawano A, Miyawaki A, Xin KQ, Ishii KJ, Kawai T, Akira S, Suzuki K, and Okuda K.
- Journal Title
  
  Proceedings National Academy of Science USA 104
  
  Pages: 14050-14050
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Blocking of the TLR5 activation domain hampers protective potential of DNA vaccine targeting flagellin2007
- Author(s)
  Saha, S., Takeshita, F., Matsuda, T., Jounai, N., Kobiyama, K., Matsumoto, T., Sasaki, S., Yoshida, A., Xin, KQ., Klinman, DM., Uematsu, S., Ishii, KJ., Akira, S., Okuda, K
- Journal Title
  
  J. Immunol 179
  
  Pages: 1147-1154
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] The degree of apoptosis as an immunostimulant for a DNA vaccine against HIV-1 infection2007
- Author(s)
  Kojima, Y., Jounai, N., Takeshita, F., Nakazawa, M., Okuda, K., Watabe, S., Xin, KQ., Okuda, K
- Journal Title
  
  Vaccine 25
  
  Pages: 438-445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Blocking of the TLR5 activation domain hampers protective potential of DNA vaccine targeting flagellin2007
- Author(s)
  Saha S, Takeshita F, Matsuda T, Jounai N, Kobiyama K, Matsumoto T, Sasaki S, Yoshida A, Xin KQ, Klinman DM, Uematsu S, Ishii KJ, Akira S, and Okuda K.
- Journal Title
  
  The Journal of Immunology 179
  
  Pages: 1147-1154
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] TLR9 expression and function is abolished by the cervical cancer-associated human papillomavirus type 16.2007
- Author(s)
  Hasan UA, Bates E, Takeshita F, Biliato A, Accardi R, Bouvard V, Mansour M, Vincent I, Gissmann L, Iftner T, Sideri M, Stubenrauch F, Tommasino M.
- Journal Title
  
  J.Immunol. 178
  
  Pages: 3186-3197
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Muscle creatine kinase/SV 40 hybrid promoter for muscle-targeted long-term transgene expression.2007
- Author(s)
  Takeshita F
- Journal Title
  
  Int.J.Mol.Med. 19
  
  Pages: 309-309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659128
[Journal Article] Muscle creatine kinase/SV 40 hybrid promoter for muscle-targeted long-term transgene expression.2007
- Author(s)
  Takeshita F
- Journal Title
  
  Int. J. Mol. Med. 19
  
  Pages: 309-309
- Data Source
  KAKENHI-PROJECT-18659128
[Journal Article] Blocking of the TLR5 activation domain hampers protective potential of DNA vaccine targeting flagellin.2007
- Author(s)
  Saha S, Takeshita F. Matsuda T, Jounai N, Kobiyama K, Matsumoto T, Sasaki S, Yoshida A, Xin KQ, Klinman DM, Uematsu S, Ishii KJ, Akira S, and Okuda K.
- Journal Title
  
  The Journal of Immunology 179
  
  Pages: 1147-1154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] The Atg5-Atg12 conjugate associates with innate antiviral immune responses.2007
- Author(s)
  Jounai N, Takeshita F. Kobiyama K, Sawano A, Miyawaki A, Xin KQ, Ishii KJ, Kawai T, Akira S, Suzuki K, and Okuda K.
- Journal Title
  
  Proceedings National Academy of Science USA 104
  
  Pages: 14050-14050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Muscle creatine kinase/SV 40 hybrid promoter for muscle-targeted long-term transgene expression.2007
- Author(s)
  Takeshita F, Takase K, Tozuka M, Saha S, Okuda K, Ishii N, and Sasaki S
- Journal Title
  
  International Journal of Molecular Medicine 19
  
  Pages: 309-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Suppression of iodide uptake and thyroid hormone synthesis with stimulation of the type I interferon system by double-stranded RNA(dsRNA)in cultured human thyroid follicles2007
- Author(s)
  Yamazaki, K., Suzuki, K., Yamada, E., Yamada, T., Takeshita, F., Matsumoto, M., Mitsuhashi, T., Obara, T., Takano, K., Sato, K
- Journal Title
  
  Endocrinology 148
  
  Pages: 3226-3235
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Suppression of iodide uptake and thyroid hormone synthesis with stimulation of the type I interferon system by double-stranded RNA(dsRNA) in cultured human thyroid follicles2007
- Author(s)
  Yamazaki K, Suzuki K, Yamada E, Yamada T, Takeshita F, Matsumoto M, Mitsuhashi T, Obara T, Takano K, and Sato K.
- Journal Title
  
  Endocrinology 148
  
  Pages: 13226-3235
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Suppression of iodide uptade and thyroid hormone synthesis with stimulation of the type I interferon system by double-stranded RNA (dsRNA) in cultured human thyroid follicles.2007
- Author(s)
  Yamazaki K, Suzuki K, Yamada E, Yamada T, Takeshita F, Matsumoto M, Mitsuhashi T, Obara T, Takano K, Sato K
- Journal Title
  
  Endocrinology (in press)
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Muscle creatine kinase/SV 40 hybrid promoter for muscle-targeted long-term transgene expression.2007
- Author(s)
  Takeshita F, Takase K, Tozuka M, Saha S, Okuda K, Ishii N, Sasaki S.
- Journal Title
  
  Int.J.Mol.Med. 19
  
  Pages: 309-315
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] TLR9 gexpression and functionis abolished by the cervical cancer-assocfated human papillomavirus type 162007
- Author(s)
  Hasan UA, Bates E, Takeshita F, Biliato A, Accardi R, Bouvard V, Mansour M, Vincent I, Gissmann L, Iftner T, Sideri M, Stubenrauch F, and Tommasino M.
- Journal Title
  
  The Journal of Immunology 178
  
  Pages: 3186-3197
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] TLR9 expression and function is abolished by the cervical cancer-associated human papillomavirus type 16.2007
- Author(s)
  Hasan UA, Bates E, Takeshita F, Biliato A, Accardi R, Bouvard V, Mansour M, Vincent I, Gissmann L, Iftner T, Sideri M, Stubenrauch F, and Tommasino M.
- Journal Title
  
  The Journal of Immunology 178
  
  Pages: 3186-3197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Suppression of iodite uptake and thyroid hormone synthesis with stimulation of the type I interferon system by double-stranded RNA (dsRNA) in cultured human thyroid follicles.2007
- Author(s)
  Yamazaki K, Suzuki K, Yamada E, Yamada T, Takeshita F, Matsumoto M, Mitsuhashi T, Obara T, Takano K, Sato K
- Journal Title
  
  Endocrinology (in press)
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Mutant influenza A virus nucleoprotein is preferentially localized in the cytoplasm and its immunization in mice shows higher immunogenicity and cross-reactivity2007
- Author(s)
  Ohba, K., Yoshida, S., Zahidunnabi, Dewan, M., Shimura, H., Sakamaki, N., Takeshita, F., Yamamoto, N., Okuda ,K
- Journal Title
  
  Vaccine 25
  
  Pages: 4291-4300
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Muscle creatine kinase/SV 40 hybrid promoter for muscle-targeted long-term transgene expression2007
- Author(s)
  Takeshita F, Takase K, Tozuka M, Saha S, Okuda K, Ishii N, and Sasaki S
- Journal Title
  
  International Journal of Molecular Medicine 19
  
  Pages: 309-335
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] The degree of apoptosis as an immunostimulant for a DNA vaccine against HIV-1 infection.2007
- Author(s)
  Kojima Y, Jounai N, Takeshita F, Nakazawa M, Okuda K, Watabe S, Xin KQ, Okuda K.
- Journal Title
  
  Vaccine 25
  
  Pages: 438-445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Suppression of iodide uptake and thyroid hormone synthesis with stimulation of the type I interferon system by double-stranded RNA (dsRNA) in cultured human thyroid follicles.2007
- Author(s)
  Yamazaki K, Suzuki K, Yamada E, Yamada T, Takeshita F, Matsumoto M, Mitsuhashi T, Obara T, Takano K, Sato K
- Journal Title
  
  Endocrinology (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Blocking of the TLR5 activation domain hampers protective potential of DNA vaccine targeting flagellin.2007
- Author(s)
  Saha S, Takeshita F, Matsuda T, Jounai N, Kobiyama K, Matsumoto T, Sasaki S, Yoshida A, Xin KQ, Klinman DM, Uematsu S, Ishii KJ, Akira S, Okuda K.
- Journal Title
  
  J.Immunol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Muscle creatine kinase/SV 40 hybrid promoter for muscle-targeted long-term transgene expression.2007
- Author(s)
  Takeshita F
- Journal Title
  
  Int.J.Mol.Med. 19
  
  Pages: 309-309
- Data Source
  KAKENHI-PROJECT-15390296
[Journal Article] Mutant influenza A virus nucleoprotein is preferentially localized in the cytoplasm and its immunization in mice shows higher immunogenicity and cross-reactivity2007
- Author(s)
  Ohba K, Yoshida S, Zahidunnabi Dewan M, Shimura H, Sakamaki N, Takeshita F, Yamamoto N, and Okuda K.
- Journal Title
  
  Vaccine 25
  
  Pages: 4291-4300
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Muscle creatine kinase/SV 40 hybrid promoter for muscle-targeted long-term transgene expression2007
- Author(s)
  Takeshita F, Takase K, Tozuka M, Saha S, Okuda K, Ishii N, Sasaki S
- Journal Title
  
  Int. J. Mol. Med. 19
  
  Pages: 309-315
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Mutant influenza A virus nucleoprotein is preferentially localized in the cytoplasm and its immunization in mice shows higher immunogenicity and cross-reactivity.2007
- Author(s)
  Ohba K, Yoshida S, Zahidunnabi Dewan M, Shimura H, Sakamaki N, Takeshita F, Yamamoto N, and Okuda K.
- Journal Title
  
  Vaccine 25
  
  Pages: 4291-4300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Suppression of iodide2007
- Author(s)
  Yamazaki K, Suzuki K, Yamada E, Yamada T, Takeshita F, Matsumoto M, Mitsuhashi T, Obara T, Takano K, Sato K.
- Journal Title
  
  Endocrinology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Muscle creatine kinase/SV 40 hybrid promoter for muscle-targeted long-term transgene expression2007
- Author(s)
  Takeshita, F., Takase, K., Tozuka, M., Saha, S., Okuda, K., Ishii, N., Sasaki, S
- Journal Title
  
  Int. J. Mol. Med 19
  
  Pages: 309-315
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] The Atg5-Atgl2 conjugate associates with innate antiviral immune responses2007
- Author(s)
  Jounai, N., Takeshita, F., Kobiyama, K., Sawano, A., Miyawaki, A., Xin KQ., Ishii ,KJ., Kawai, T., Akira, S., Suzuki, K., Okuda, K
- Journal Title
  
  Proc. Natl, Acad. Sci. USA 104
  
  Pages: 14050-14055
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Muscle creative kinase/SV40 hybrid promoter for muscle-targeted long-term transgene expression.2007
- Author(s)
  Takeshita F, et. al.
- Journal Title
  
  Int J Mol Med 19(2)
  
  Pages: 309-315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659111
[Journal Article] The degree of apoptosis as an immunostimulant for a DNA vaccine against HIV-1 infection2007
- Author(s)
  Kojima Y, Jounai N, Takeshita F, Nakazawa M, Okuda K, Watabe S, Xin KQ, Okuda K.
- Journal Title
  
  Vaccine 25
  
  Pages: 438-445
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] TLR9 expression and function is abolished by the cervical cancer-associated human papillomavirus type 162007
- Author(s)
  Hasan ,UA., Bates, E., Takeshita, F., Biliato, A., Accardi, R., Bouvard, V., Mansour, M., Vincent, I., Gissmann, L., Iftner, T., Sideri, M., Stubenrauch, F., Tommasino, M
- Journal Title
  
  J. Immunol 178
  
  Pages: 3186-3197
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Multivalent DNA vaccine protects mice against pulmonary infection caused by Pseudomonas aeruginosa2006
- Author(s)
  Saha S, Takeshita F, Sasaki S, Matsuda T, Tanaka T, Tozuka M, Takase K, Matsumoto T, Okuda K, Ishii N, Yamaguchi K, Xin KQ, Klinman DM, Okuda K
- Journal Title
  
  Vaccine 24
  
  Pages: 6240-6249
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Double stranded B-DNA activates type-I IFNs gene program via IPS-1/TBK1 pathway.2006
- Author(s)
  Ishii KJ, Coban C, Kato H, Takahashi K, Torii Y, Takeshita F, Ludwig H, Sutter G, Suzuki K, Hemmi H, Sato S, Tamamoto M, Uematsu S, Kawai T, Takeuchi 0, Akira S.
- Journal Title
  
  Nat.Immunol. 7
  
  Pages: 40-48
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] A fused gene of nucleoprotein (NP) and herpes simplex virus genes (VP22) induces highly protective immunity against different subtypes of influenza virus.2006
- Author(s)
  Saha S, Yoshida S, Ohba K, Matsui K, Matsuda T, Takeshita F, Umeda K, Tamura Y, Okuda K, Klinman D, Xin KQ, Okuda K.
- Journal Title
  
  Virology 35
  
  Pages: 48-57
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Activator protein 1-mediated transcriptional regulation strategy sustains long-term expression of a xenogeneic gene product in vivo : An implication for gene therapy targeting congenital protein deficiencies.2006
- Author(s)
  Sasaki S, Smith JM, Takase K, Okuda K, Ishii N, Takeshita F.
- Journal Title
  
  Int.J.Mol.Med. 18
  
  Pages: 289-297
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Multivalent DNA vaccine protects mice against pulmonary infection caused by Pseudomonas aeruginosa.2006
- Author(s)
  Saha S, Takeshita F, Sasaki S, Matsuda T, Tanaka T, Tozuka M, Takase K, Matsumoto T, Okuda K, Ishii N, Yamaguchi K, Xin KQ, Klinman DM, Okuda K.
- Journal Title
  
  Vaccine 24
  
  Pages: 6240-6249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] TLR-adaptor molecules enhance DNA-raised adaptive immune responses against flu and tumor challenge through the activation of innate immunity2006
- Author(s)
  Takeshita F, Tanaka T, Matsuda T, Tozuka M, Kobiyama K, Saha S, Matsui K, Ishii KJ, Coban C, Akira S, Ishii N, Suzuki K, Klinman DM, Okuda K, and Sasai S
- Journal Title
  
  The Journal of Virology 80
  
  Pages: 6218-6224
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Activator protein 1-mediated transcriptional regulation strategy sustains long-term expression of a xenogeneic gene product in vivo : An implication for gene therapy targeting congenital protein deficiencies2006
- Author(s)
  Sasaki S, Smith JM, Takase K, Okuda K, Ishii N, Takeshita F
- Journal Title
  
  Int. J. Mol. Med. 18
  
  Pages: 289-297
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] A fused gene of nucleoprotein(NP)and herpes simplex virus genes(VP22)induces highly protective immunity against different subtypes of influenza virus2006
- Author(s)
  Saha, S., Yoshida, S., Ohba, K., Matsui, K., Matsuda, T., Takeshita, F., Umeda, K., Tamura, Y., Okuda, K., Klinman D., Xin, KQ., Okuda, K
- Journal Title
  
  Virology 35
  
  Pages: 48-57
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] TLR-adaptor molecules enhance DNA-raised adaptive immune responses against flu and tumor challenge through the activation of innate immunity2006
- Author(s)
  Takeshita F, Tanaka T, Matsuda T, Tozuka M, Kobiyama K, Saha S, Matsui K, Ishii KJ, Coban C, Akira S, Ishii N, Suzuki K, Klinman DM, Okuda K, Sasai S
- Journal Title
  
  J. Virol 80
  
  Pages: 6218-6224
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Toll-like receptor adaptor molecules enhance DNA-raised adaptive immune responses against influenza and tumors through activation of innate immunity.2006
- Author(s)
  Takeshita F, Tanaka T, Matsuda T, Tozuka M, Takase K, Saha S, Matsui K, Ishii KJ, Coban C, Akira S, Ishii N, Suzuki K, Klinman DM, Okuda K, Sasaki S.
- Journal Title
  
  J Virol. 80
  
  Pages: 6218-6224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390296
[Journal Article] Localization of C0R01A in the Macrophages Containing Mycobacterium leprae2006
- Author(s)
  Suzuki, K., Takeshita, F., Nakata, N., Ishii, N., Makino, M
- Journal Title
  
  Acta. Histochem. Cytochem 39
  
  Pages: 107-112
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] TLR-adaptor molecules enhance DNA-raised adaptive immune responses against flu and tumor challenge through the activation of innate immunity2006
- Author(s)
  Takeshita F, Tanaka T, Matsuda T, Tozuka M, Kobiyama K, Saha S, Matsui K, Ishii KJ, Coban C, Akira S, Ishii N, Suzuki K, Klinman DM, Okuda K, Sasaki S
- Journal Title
  
  J. Virol 80
  
  Pages: 6218-6224
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Activator protein 1-mediated transcriptional regulations strategy sustains long-term expression of a xenogeneic gene product invivo: An implication for gene therapy tareeting coneenital protein deficiencies2006
- Author(s)
  Sasaki S, Smith JM, Takase K, Okuda K, Ishii N, and Takeshita F
- Journal Title
  
  International Journal of Molecular Medicine 18
  
  Pages: 289-297
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Multivalent DNA vaccine protects mice against pulmonary infection caused by Pseudomonas aeruginosa2006
- Author(s)
  Saha, S., Takeshita, F., Sasaki, S., Matsuda, T., Tanaka, T., Tozuka, M., Takase, K., Matsumoto, T., Okuda, K., Ishii, N., Yamaguchi, K., Xin, KQ., Klinman, DM., Okuda, K
- Journal Title
  
  Vaccine 24
  
  Pages: 6240-6249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] TLR-adaptor molecules enhance DNA-raised adaptive immune responses against flu and tumor challenge through the activation of innate immunity.2006
- Author(s)
  Takeshita F, Tanaka T, Matsuda T, Tozuka M, Kobiyama K, Saha S, Matsui K, Ishii KJ, Coban C, Akira S, Ishii N, Suzuki K, Klinman DM, Okuda K, Sasaki S.
- Journal Title
  
  J.Virol. 80
  
  Pages: 6218-6224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Saha2006
- Author(s)
  Takeshita, F., Tanaka, T., Matsuda, T., Tozuka, M., Kobiyama, K
- Journal Title
  
  J. Virol 80
  
  Pages: 6218-6224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Toll-like receptor adaptor molecules enhance DNA-raised adaptive immune responses against influenza and tumors through activation of innate immunity2006
- Author(s)
  Takeshita F
- Journal Title
  
  J Virol 80
  
  Pages: 6218-6218
- Data Source
  KAKENHI-PROJECT-18659128
[Journal Article] A fused gene of nucleoprotein (NP) and herpes simplex virus genes (VP22) induces highly protective immunity against different subtypes of influenza virus2006
- Author(s)
  Saha S, Yoshida S, Ohba K, Matsui K, Matsuda T, Takeshita F, Umeda K, Tamura Y, Okuda K, Klinman D, Xin KQ, Okuda K
- Journal Title
  
  Virology 35
  
  Pages: 48-57
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] TLR-adaptor molecules enhance DNA-raised adaptive immune responses against flu and tumor challenge trough the activation of innate immunity.2006
- Author(s)
  Takeshita F et al.
- Journal Title
  
  J. Virol 80・13
  
  Pages: 6218-6224
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390129
[Journal Article] Toll-like receptor adaptor molecules enhance DNA-raised adaptive immune responses against influenza and tumors through activation of innate immunity.2006
- Author(s)
  Takeshita F
- Journal Title
  
  J Virol 80
  
  Pages: 6218-6224
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390296
[Journal Article] Activator protein 1-mediated transcriptional regulation strategy sustains long-term expression of a xenogeneic gene product in vivo: An implication for gene therapy targeting congenital protein deficiencies2006
- Author(s)
  Sasaki, S., Smith, JM., Takase, K., Okuda, K., Ishii, N., Takeshita, F
- Journal Title
  
  Int. J. Mol. Med 18
  
  Pages: 289-297
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Localization of CORO1A in the macrophages containing Mycobacterium leprae.2006
- Author(s)
  Suzuki.K, Takeshita F, Nakata N, Ishii N, Makino M.
- Journal Title
  
  Ada Histochem Cytochem 39(4)
  
  Pages: 107-112
- NAID
  110006203399
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390296
[Journal Article] A TLR-independent antiviral response induced by double-stranded B-DNA.2006
- Author(s)
  Ishii KJ, Coban C, Kato K, Takahashi K, Torii Y, Takeshita F, Ludwig H, Sutter G, Suzuki K, Hemmi H, Sto S, Yamamoto M, Uematsu S, Kawai T, Takeuchi O, Akira S.
- Journal Title
  
  Nat Immunol 7(1)
  
  Pages: 40-48
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390296
[Journal Article] TLR-adaptor molecules enhance DNA-raised adaptive immune responses against flu and tumor challenge trough the activation of innate immunity.2006
- Author(s)
  Takeshita F et al.
- Journal Title
  
  J.Virol 80, 13
  
  Pages: 6218-6224
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390129
[Journal Article] A fused gene of nucleoprotein (NP) and herpes simplex virus genes (VP22) induces highly protective immunity against different subtypes of influenza virus2006
- Author(s)
  Saha S, Yoshida S, Ohba K, Matsui K, Matsuda T, Takeshita F, Umeda K, Tamura Y, Okuda K, Klinman D, Xin KQ, Okuda K
- Journal Title
  
  Virology 35
  
  Pages: 48-57
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Multivalent DNA vaccine protects mice against pulmonary infection caused by Pseudomonas aeruginosa2006
- Author(s)
  Saha S, Takeshita F, Sasaki S, Matsuda T, Tanaka T, Tozuka M, Takase K, Matsumoto T, Okuda K, Ishii N, Yamaguchi K, Xin KQ, Klinman DM, Okuda K
- Journal Title
  
  Vaccine 24
  
  Pages: 6240-6249
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] Activator protein 1-mediated transcriptional regulation strategy sustains long-term expression of a xenogeneic gene product in vivo : An implication for gene therapy targeting congenital protein deficiencies2006
- Author(s)
  Sasaki S, Smith JM, Takase K, Okuda K, Ishii N, Takeshita F
- Journal Title
  
  Int. J. Mol. Med. 18
  
  Pages: 289-297
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] A fused gene of nucleoprotein(NP) and herpes simplex virus genes(VP22) induces highly protective immunity against different subtypes of influenza virus2006
- Author(s)
  Saha S, Yoshida S, Ohba K, Matsui K, Matsuda T, Takeshita F, Umeda K, Tamura Y, Okuda K, Klinman D, Xin KQ, and Okuda K
- Journal Title
  
  Virology 35
  
  Pages: 48-57
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590432
[Journal Article] TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF.2005
- Author(s)
  Takeshita F
- Journal Title
  
  Eur J Immunol 35(8)
  
  Pages: 2477-2485
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390296
[Journal Article] TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF.2005
- Author(s)
  Takeshita F et al.
- Journal Title
  
  Eur.J.Immunol 35, 8
  
  Pages: 2477-2485
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390129
[Journal Article] Comparison of antigen-specific cellular immune responses between individual PBMCs and splenocytes.2005
- Author(s)
  Xin K-Q, Ohta S, Jounai N, Takeshita F, Okuda K.
- Journal Title
  
  Vaccine 23
  
  Pages: 2954-2955
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF.2005
- Author(s)
  Takeshita F
- Journal Title
  
  Eur.J.Immunol. 35
  
  Pages: 2477-2477
- Data Source
  KAKENHI-PROJECT-16790267
[Journal Article] TLR9遺伝子の転写制御2005
- Author(s)
  武下文彦
- Journal Title
  
  臨床免疫 44(2)
  
  Pages: 131-131
- Data Source
  KAKENHI-PROJECT-15390296
[Journal Article] Prime-boost vaccination with plasmid DNA and a chimeric adenovirus type 5 vector with type 35 fiber induces protective immunity against HIV.2005
- Author(s)
  Xin K-Q, Jounai N, Someya K, Honma K, Mizuguchi H, Naganawa S, Kitamura K, Hayakawa T, Saha S, Takeshita F, Okuda K, Honda M, Klinman DM, Okuda K.
- Journal Title
  
  Gene Ther. 12
  
  Pages: 1769-1777
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF2005
- Author(s)
  Takeshita F
- Journal Title
  
  Eur J Immunol 35(8)
  
  Pages: 2477-2477
- Data Source
  KAKENHI-PROJECT-15390296
[Journal Article] DNAワクチンの可能性2005
- Author(s)
  武下文彦
- Journal Title
  
  臨床と微生物 32
  
  Pages: 275-275
- NAID
  10015687427
- Data Source
  KAKENHI-PROJECT-16790267
[Journal Article] Hyperproduction of IFN-g by CpG Oligodeoxynucleotide-iduced exacerbation of atopic dermatitis-like skin lesion in some NC/Nga mice. J.2005
- Author(s)
  Takakura M, Takeshita F, Aihara M, Xin K-Q, Ichino M, Okuda K, Ikezawa Z
- Journal Title
  
  J.Invest.Dermatol. 125
  
  Pages: 1156-1162
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Identification of novel single stranded RNA that stimulates human CD14+ CD11c+ monocytes.2005
- Author(s)
  Sugiyama T, Gursel M, Takeshita F, Conover J, Akira S, Klinman DM, Ishii KJ. CpG RNA
- Journal Title
  
  J.Immunol. 174
  
  Pages: 2273-2279
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] DNAワクチンの可能性2005
- Author(s)
  武下文彦
- Journal Title
  
  臨床と微生物 32
  
  Pages: 275-275
- NAID
  10015687427
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF.2005
- Author(s)
  Takeshita F et al.
- Journal Title
  
  Eur. J. Immunol 35・8
  
  Pages: 2477-2485
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390129
[Journal Article] TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF.2005
- Author(s)
  Takeshita F, Ishii KJ, Kobiyama K, Kojima Y, Coban C, Sasaki S, Ishii N, Klinman DM, Okuda K, Akira S, Suzuki K.
- Journal Title
  
  Eur J Immunol 35(8)
  
  Pages: 2477-2485
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390296
[Journal Article] TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF. Eur.2005
- Author(s)
  Takeshita F, Ishii KJ, Kobiyama K, Kojima Y, Coban C, Sasaki S, Ishii N, Klinman DM, Okuda K, Akira S, Suzuki K.
- Journal Title
  
  J.Immunol. 35
  
  Pages: 2477-85
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF2005
- Author(s)
  Takeshita, F. et al.
- Journal Title
  
  Eur.J.Immunol. 35・8
  
  Pages: 2477-2785
- Data Source
  KAKENHI-PROJECT-17390129
[Journal Article] TRAF4 acts as a silencer in TLR-mediated signaling through the association with TRAF6 and TRIF.2005
- Author(s)
  Takeshita F
- Journal Title
  
  Eur.J.Immunol. 35
  
  Pages: 2477-2477
- Data Source
  KAKENHI-PROJECT-17590425
[Journal Article] Signal transduction pathways mediated by the interaction of CpG DNA with toll-like receptor 9.2004
- Author(s)
  Takeshita F, Gursel I, Ishii KJ, Suzuki K, Gursel M, Klinman DM.
- Journal Title
  
  Semin Immunol 16
  
  Pages: 17-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390296
[Journal Article] Transcriptional regulation of the human Toll-like receptor 9 gene.2004
- Author(s)
  Takeshita F
- Journal Title
  
  J Immunol 173
  
  Pages: 2552-2561
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390296
[Journal Article] Signal transduction pathways mediated by the interaction of CpG DNA with toll-like receptor 92004
- Author(s)
  Takeshita F
- Journal Title
  
  Semin Immunol 16
  
  Pages: 17-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390296
[Journal Article] Transcriptional regulation of the human Toll-like receptor 9 gene.2004
- Author(s)
  Takeshita F, Suzuki K, Sasaki S, Ishii N, Klinman DM, Ishii KJ.
- Journal Title
  
  J Immunol 173
  
  Pages: 2552-2561
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390296
[Journal Article] Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7-and TLR9-mediated interferon-alpha induction.
- Author(s)
  Uematsu S, Sato S, Yamamoto M, Hirotani T, Kato H, Takeshita F, Matsuda M, Coban C, Ishii KJ, Kawai T, Takeuchi 0, Akira S.
- Journal Title
  
  J.Exp.Med. 201
  
  Pages: 915-923
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Patent] 染色体外ヒストンH2Bを介する二本鎖DNA認識機構の利用2009
- Inventor(s)
  武下文彦、小檜山康司、吉田篤司
- Industrial Property Rights Holder
  公立大学法人横浜市立大学
- Patent Publication Number
  2011-109982
- Filing Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-20590477
[Patent] カスパーゼリクルートメントドメインを応用した新規リコンビナントタンパク及びその用途2009
- Inventor(s)
  武下文彦、小檜山康司、奥田研爾
- Industrial Property Rights Holder
  公立大学法人横浜市立大学
- Filing Date
  2009-08-12
- Data Source
  KAKENHI-PROJECT-20590477
[Patent] 染色体外ヒストンH2Bを介する二本鎖DNA認識機構の利用2009
- Inventor(s)
  武下文彦、小檜山康司、吉田篤司
- Industrial Property Rights Holder
  公立大学法人横浜市立大学
- Patent Publication Number
  2011-109982
- Filing Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-20200074
[Patent] カスパーゼリクルートメントドメインを応用した新規リコンビナントタンパク及びその用途2009
- Inventor(s)
  武下文彦、小檜山康司、奥田研爾
- Industrial Property Rights Holder
  公立大学法人横浜市立大学
- Filing Date
  2009-08-12
- Data Source
  KAKENHI-PROJECT-20200074
[Patent] カスパーゼリクルートメントドメインを応用した新規リコンビナントタンパク及びその用途2008
- Inventor(s)
  武下文彦小檜山康司奥田研爾
- Industrial Property Rights Holder
  横浜市立大学
- Filing Date
  2008-08-29
- Data Source
  KAKENHI-PROJECT-20590477
[Patent] カスパーゼリクルートメントドメインを応用した新規リコンビナントタンパク及びその用途2008
- Inventor(s)
  武下文彦, 小檜山康司,奥田研爾
- Industrial Property Rights Holder
  横浜市立大学
- Filing Date
  2008-08-29
- Data Source
  KAKENHI-PROJECT-20200074
[Patent] フランジェリン変異体ワクチン2007
- Inventor(s)
  武下文彦, 奥田研邇, Sukumar Saha
- Industrial Property Rights Holder
  横浜市立大学
- Industrial Property Number
  2007-017446
- Filing Date
  2007-01-29
- Data Source
  KAKENHI-PROJECT-17390129
[Patent] 緑膿菌に対して感染防御能を誘導できる医薬組成物2006
- Inventor(s)
  奥田研爾, 武下文彦, Sukumar saha
- Industrial Property Rights Holder
  横浜市立大学
- Industrial Property Number
  2006-319535
- Filing Date
  2006-11-28
- Data Source
  KAKENHI-PROJECT-17390129
[Patent] 内因性自然免疫活性化分子を利用した遺伝子アジュバント2005
- Inventor(s)
  武下文彦
- Industrial Property Rights Holder
  横浜市立大学
- Filing Date
  2005-08-25
- Data Source
  KAKENHI-PROJECT-17590425
[Patent] 内因性自然免疫活性化分子を利用した遺伝子アジュバント2005
- Inventor(s)
  武下文彦
- Industrial Property Rights Holder
  横浜市立大学
- Filing Date
  2005-08-25
- Data Source
  KAKENHI-PROJECT-16790267
[Patent] 緑膿菌に対して感染防御能を誘導できる医薬組成物2004
- Inventor(s)
  武下文彦
- Industrial Property Rights Holder
  横浜市立大学
- Filing Date
  2004-11-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590425
[Presentation] A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine adjuvant.2009
- Author(s)
  武下文彦, 小檜山康司
- Organizer
  International Workshop co-sponsored by Yokohama City University & FDA.
- Place of Presentation
  Yokohama
- Year and Date
  2009-04-04
- Data Source
  KAKENHI-PROJECT-20590477
[Presentation] 自然免疫活性化機序の解明と応用2009
- Author(s)
  武下文彦
- Organizer
  第8回プロテオーム医療創薬研究会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590477
[Presentation] A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine adjuvant.2009
- Author(s)
  Takeshita F, Kobiyama K.
- Organizer
  International Workshop co-sponsored by Yokohama City University, FDA.
- Place of Presentation
  Yokohama.
- Year and Date
  2009-03-04
- Data Source
  KAKENHI-PROJECT-20200074
[Presentation] A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine adjuvant.2009
- Author(s)
  小檜山康司, 石井健, 武下文彦
- Organizer
  Keystone Symposia on Molecular and Cellular Biology.
- Place of Presentation
  Banff, Alberta, Canada
- Data Source
  KAKENHI-PROJECT-20590477
[Presentation] A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine2009
- Author(s)
  Kobiyama K, Ishii KJ, Takeshita F
- Organizer
  Keystone Symposia on Molecular and Cellular Biology
- Place of Presentation
  カナダ、バンプ
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-20200074
[Presentation] A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine adjuvant.2009
- Author(s)
  Kobiyatna K, Ishii KJ, Takeshita F.
- Organizer
  Keystone Symposia on Molecular and Cellular Biology.
- Place of Presentation
  カナダ、パンフ
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-20590477
[Presentation] 自然免疫活性化機序の解明と応用.2009
- Author(s)
  武下文彦
- Organizer
  第8回プロテオーム医療創薬研究会.
- Place of Presentation
  横浜.
- Data Source
  KAKENHI-PROJECT-20200074
[Presentation] IPS-1変異体による新規自然免疫活性化メカニズムの解析および免疫調節薬への応用2008
- Author(s)
  小檜山康司、武下文彦、石井健、鈴木幸一、奥田研爾
- Organizer
  第19回日本生体防御学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20590477
[Presentation] Histone H2B mediates intracellular recognition of naked DNA and production of tvoe I interferons2007
- Author(s)
  Takeshita, F., Kobiyama, K., Suzuki, K
- Organizer
  The 30th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Presentation] Blocking of the TLR5 activation domain hampers protective potential of DNA vaccine targeting flagellin2007
- Author(s)
  Takeshita F, Saha S, Kobiyama K, Jounai N, and Okuda K
- Organizer
  第20回内藤カンファランス
- Place of Presentation
  葉山
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Presentation] The Atg5-Atg12 conjugate associates with innate antiviral immune responses2007
- Author(s)
  Jounai N, Takeshita F, Kobiyama K, Huang J, Suzuki K
- Organizer
  THE 20TH NAITO CONFERENCE ON Innate Immunity in Medicine and Biology[III]
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-19659111
[Presentation] Atg family members associate with the dsRNA-mediated innate antivirus immune pathway2007
- Author(s)
  Takeshita, F., Jounai, N., Kobiyama, K., Okuda, K
- Organizer
  The 80th Annual Meeting of the Japanese Society for Bacteriology
- Place of Presentation
  Osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Presentation] Autophagy-related Atg family members associate with the dsRNA-mediated innate anti-virus immune pathway2007
- Author(s)
  Kobiyama, K., Jounai, N., Takeshita F
- Organizer
  Keystone Symposia on Molecular and Cellular Biology
- Place of Presentation
  Keystone, CO, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Presentation] Blocking of the TLR5 activation domain hampers protective potential of DNA vaccine targeting flagellin2007
- Author(s)
  Takeshita F, Saha S, Kobiyama K, Jounai N, Okuda K
- Organizer
  THE 20TH NAITO CONFERENCE ON Innate Immunity in Medicine and Biology[III]
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-19659111
[Presentation] Autophagy-related Atg family members associate with the dsRNA-mediated innate anti-virus immune pathway2007
- Author(s)
  Kobiyama K, Jounai N, and Takeshita F
- Organizer
  Keystone Symposiaon Molecular and Cellular Biology
- Place of Presentation
  Keystone,Colorado
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Presentation] Blocking of the TLR5 activation domain hampers protective potential of DNA vaccine targeting flagellin.2007
- Author(s)
  Takeshita F, Saha S, Kobiyama K, Jounai N, and Okuda K
- Organizer
  第20回内藤カンファランス
- Place of Presentation
  葉山
- Data Source
  KAKENHI-PROJECT-18590432
[Presentation] The Atg5-Atg12 conjugate associates with innate antiviral immune responses2007
- Author(s)
  Fumihiko Takeshita
- Organizer
  第18回日本生体防御学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-18659128
[Presentation] Histone H2B mediates intracellular recognition of naked DNA and production of type Iinterferons2007
- Author(s)
  Takeshita F, Kobiyama K, Suzuki K.
- Organizer
  第30回目本分子生物学会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590432
[Presentation] Histone H2B mediates intracellular recognition of naked DNA and production of type I interferons2007
- Author(s)
  Takeshita F, Kobiyama K, Suzuki K.
- Organizer
  第30回日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18590432
[Presentation] コアヒストンを介する細胞内異常DNA認識機構2007
- Author(s)
  武下文彦
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18659128
[Presentation] istone H2B mediates intracellular recognition of naked DNA and production of type I interferons2007
- Author(s)
  Kobiyama K, Takeshita F, Jounai N, Okuda K, Ishii KJ, Suzuki K
- Organizer
  THE 20TH NAITO CONFERENCE ON Innate Immunity in Medicine and Biology[III]
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-19659111
[Presentation] コアヒストンを介する細胞内異常DNA認識機構2007
- Author(s)
  武下文彦, 小檜山康司, 鈴木幸一
- Organizer
  BMB2007
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-19659111
[Presentation] Blocking of the TLR5 activation domain hampers protective potential of DNA vaccine targeting flagellin2007
- Author(s)
  Takeshita, F., Saha, S., Kobiyama, K., Joubai, N., Okuda, K
- Organizer
  The 20th Naito Conference On Innate Immunity in Medicine and Biology III
- Place of Presentation
  Hayama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590432

1. SUZUKI Koichi (20206478)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
2. SASAKI Shin (40342901)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. ISHII Ken (00448086)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. OKUDA Kenji (40124862)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. AKIRA Shizuo (50192919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. HORII Toshihiro (80142305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHINADA Masaru (40301452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. AIHARA Michiko (90231753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. IKEZAWA Zenro (90046128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KANBARA Takeshi (70347293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. COBAN Cevayir (00397712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. KOYAMA Shohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. KAWAGOE Tatsukata

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Takeshita Fumihiko 武下 文彦

TAKESHITA FUMIHIKO 武下 文彦

KAKESHITA Humihiko

Research Projects

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Co-Researchers

Development immunomodulative drug based on the recognition mechanism of viral B-DNA.Principal Investigator

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Elucidation of the mechanism underlying core histone-mediated antiviral innate immune responsePrincipal Investigator

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Research on molecular mechanisms of double stranded DNA-mediated innate immune activationPrincipal Investigator

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内因性自然免疫活性化分子を用いたDNAワクチンの免疫原性増幅法Principal Investigator

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[Journal Article] Mutant mouse p53 transgene elevates the chemical induction of tumors that respond to gene silencing with siRNA.2010

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Data Source

[Journal Article] Extrachromosomal histone H2B mediates innate antiviral immune responses induced by intracellular double-stranded DNA.2010

Author(s)

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Data Source

[Journal Article] Extrachromosomal histone H2B mediates innate antiviral immune responses induced by intracellular double-stranded DNA.2010

Author(s)

Takeshita Fumihiko 武下文彦

TAKESHITA FUMIHIKO 武下文彦