Takano Hiroyuki 高野博之

… Alternative Names

TAKANO HIROYUKI 高野博之

TAKANO Hiroyuki 高野博之

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Researcher Number	60334190
Other IDs
External Links
Affiliation (Current)	2025: 千葉大学, 大学院薬学研究院, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 千葉大学, 大学院薬学研究院, 教授 2008: 千葉大学, 医学部・附属病院循環器内科, 講師 2007: 千葉大学, 医学部附属病院, 講師 2002 – 2005: 千葉大学, 大学院・医学研究院, 助手 2004: 千葉大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 52010:General internal medicine-related / Medical pharmacy / Circulatory organs internal medicine
Keywords	Principal Investigator 心不全 / バイオマーカー / angiotensin II / PPARγ / VGLL3 / 骨格筋 / 性差 / 治療法 / 拡張不全 / 心臓保護活性物質 … More / DPP-4 / トランスクリプトーム解析 / knockout mouse / heart failure / cardiac hypertrophy / thiazolidinedione / ノックアウトマウス / チアゾリジン誘導体 / アンジオテンシンII / 心肥大 … More Except Principal Investigator 動脈硬化 / シグナル伝達 / Nkx2-5 / Csx / Akt / Ras / 細胞老化 / 心不全 / 分子生物学 / lncRNA / IncRNA / エピゲノム / ncRNA / 薬学 / 在宅患者訪問薬剤管理指導 / 居宅療養管理指導 / 多職種連携 / 地域包括ケア / 薬剤師 / 在宅医療 / knockout mice / protein kinase / P19Cl6 cell / zinc finger protein / LIM protein / transcriptional regulation / cardiomyocytes differentiation / P19CL6細胞 / 核外移行シグナル / タンパク質間相互作用 / 転写因子 / Kruppel-associated box / ノックアウトマウス / リン酸化酵素 / P19C16細胞 / ジンクフィンガー / LIMタンパク / 転写制御 / 心臓発生 / Insulin / Angiotensin II / Telomere / Vascular aging / Cellular senescence / 糖尿病 / 動脈瘤 / p21 / p53 / インスリン / アンジオテンシンII / テロメア / 血管老化 / 内皮障害 / サイトカイン治療 / G-CSF / 心室リモデリング / アンジオテンシンII受容体ブロッカー / ジフテリア毒素 / タモキシフェン / コンディショナルノックアウトマウス / トランスジェニックマウス / オートファジー / 細胞死 / 拡張型心筋症 Less

新規褐色脂肪細胞誘導法の開発と肥満・代謝性疾患治療への応用
- Principal Investigator
  
  山口憲孝
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Chiba University
骨格筋の線維タイプに着目した新たな心不全治療戦略の開発Principal Investigator
- Principal Investigator
  
  高野博之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Chiba University
Identification of tumor-promoting roles of the Hippo tumor-suppressing signaling
- Principal Investigator
  
  Yamaguchi Noritaka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Chiba University
Pathophysiology and therapies of HFpEFPrincipal Investigator
- Principal Investigator
  
  Takano Hiroyuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Chiba University
Elucidation of the mechanism of cellular senescence via senescence-associated lncRNA and p53 transcription complex
- Principal Investigator
  
  Hashimoto Naoko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Chiba University
Exploratory research on novel cardioprotective agentsPrincipal Investigator
- Principal Investigator
  
  TAKANO HIROYUKI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Chiba University
Development of a pharmacist training program that can play an active role in home care - pharmaceutical care of heart failure patients -
- Principal Investigator
  
  Sekine Yuko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Chiba University
The mechanisms of the inhibitory effect of G-CSF on the progression of atherosclerosis
- Principal Investigator
  
  HASEGAWA Hiroshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Chiba University
誘導型心不全モデルマウスを用いた、心不全の病態解明と新たな心不全治療法の開発
- Principal Investigator
  
  KOMURO Issei
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Chiba University
Molecular Mechanisms of Cardiomyocyte Differentiation
- Principal Investigator
  
  KOMURO Issei
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Chiba University
Establishment of mouse model and treatment for vascular aging
- Principal Investigator
  
  MINAMINO Tohru
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Chiba University
ROLES OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR γ IN CARDIOVASCULAR DISEASEPrincipal Investigator
- Principal Investigator
  
  TAKANO Hiroyuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  CHIBA UNIVERSITY

All 2024 2023 2022 2021 2020 2019 2018 2017 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Mitochondrial protein C15ORF48 is a stress-independent inducer of autophagy that regulates oxidative stress and autoimmunity2024
- Author(s)
  Takakura Y、Machida M、Terada N、Katsumi Y、Kawamura S、Horie K、Miyauchi M、Ishikawa T、Akiyama N、Seki T、Miyao 、Hayama Mio、Endo R、Ishii H、Maruyama Y、Hagiwara N、Kobayashi T J.、Yamaguchi N、Takano H、Akiyama T、Yamaguchi N
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 953-953
- DOI
  10.1038/s41467-024-45206-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06385, KAKENHI-PROJECT-20K07332, KAKENHI-PROJECT-21K06543, KAKENHI-PROJECT-21K08121, KAKENHI-PROJECT-22K20706
[Journal Article] VGLL3 confers slow-twitch muscle differentiation via PGC-1α expression in C2C12 myocytes2023
- Author(s)
  Takakura Yuki、Suzuki Takayuki、Hirai Naoto、Araki Takuro、Ohishi Mai、Sato Hiromi、Yamaguchi Naoto、Takano Hiroyuki、Yamaguchi Noritaka
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 669 Pages: 30-37
- DOI
  10.1016/j.bbrc.2023.05.073
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06543, KAKENHI-PROJECT-21K08121, KAKENHI-PROJECT-22K20706
[Journal Article] VGLL3 increases the dependency of cancer cells on de novo nucleotide synthesis through GART expression2022
- Author(s)
  Kawamura T., Takehora Y., Hori N., Takakura Y., Yamaguchi, N., Takano, H., and Yamaguchi, N.
- Journal Title
  
  J. Cell. Biochem.
  
  Volume: - Issue: 6 Pages: 1064-1076
- DOI
  10.1002/jcb.30251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22482, KAKENHI-PROJECT-21K06543, KAKENHI-PROJECT-21K08121, KAKENHI-PROJECT-22K20706, KAKENHI-PROJECT-22KJ0459
[Journal Article] Vestigial-like family member 3 stimulates cell motility by inducing High mobility group AT-hook 2 expression in cancer cells.2022
- Author(s)
  Hori, N., Takakura, Y., Sugino, A., Iwasawa, S., Nomizo, K., Yamaguchi, N., Takano, H., and Yamaguchi, N.
- Journal Title
  
  J. Cell. Mol. Med.
  
  Volume: - Issue: 9 Pages: 2686-2697
- DOI
  10.1111/jcmm.17279
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22482, KAKENHI-PROJECT-21K06543, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-21K08121, KAKENHI-PROJECT-22K20706, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-22KJ0459
[Journal Article] VGLL3 activates inflammatory responses by inducing interleukin-1α secretion.2021
- Author(s)
  Takakura, Y., Hori, N., Terada, N., Machida, M., Yamaguchi, N., Takano, H., and Yamaguchi, N.
- Journal Title
  
  FASEB J.
  
  Volume: 35 Issue: 11
- DOI
  10.1096/fj.202100679rr
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22482, KAKENHI-PROJECT-21K06543, KAKENHI-PROJECT-21K08121, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-22KJ0459
[Journal Article] Vestigial-like family member 3 (VGLL3), a cofactor for TEAD transcription factors, promotes cancer cell proliferation by activating the Hippo pathway2020
- Author(s)
  Hori Naoto、Okada Kazuyuki、Takakura Yuki、Takano Hiroyuki、Yamaguchi Naoto、Yamaguchi Noritaka
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 26 Pages: 8798-8807
- DOI
  10.1074/jbc.ra120.012781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22482, KAKENHI-PROJECT-18K08026, KAKENHI-PROJECT-16H06276
[Journal Article] Home Medical Care for Heart Failure Patients: Pharmaceutical Education Program of Chiba University2018
- Author(s)
  高野博之
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 138 Issue: 6 Pages: 783-785
- DOI
  10.1248/yakushi.17-00209-1
- NAID
  130007382207
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-06-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08393
[Journal Article] Analysis of the Correlation between the Myocardial Expression of DPP-4 and the Clinical Parameters of Patients with Heart Failure2018
- Author(s)
  Kobara Y, Hasegawa H, Hirose M, Takano H, Kobayashi Y.
- Journal Title
  
  Int. Heart J.
  
  Volume: 59 Issue: 6 Pages: 1303-1311
- DOI
  10.1536/ihj.17-547
- NAID
  130007522190
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2018-11-30
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08026
[Journal Article] Forkhead box protein A1 confers resistance to transforming growth factor‐β‐induced apoptosis in breast cancer cells through inhibition of Smad3 nuclear translocation2018
- Author(s)
  Hirata Kensuke、Takakura Yuki、Shibazaki Misato、Morii Mariko、Honda Takuya、Oshima Motohiko、Aoyama Kazumasa、Iwama Atsushi、Nakayama Yuji、Takano Hiroyuki、Yamaguchi Naoto、Yamaguchi Noritaka
- Journal Title
  
  Journal of Cellular Biochemistry
  
  Volume: 120 Issue: 2 Pages: 2259-2270
- DOI
  10.1002/jcb.27551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16J04363, KAKENHI-PROJECT-16K08227, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K08026
[Journal Article] 急性心筋梗塞に対するG-CSF治療の臨床研究-現状と問題点Annual Review2008
- Author(s)
  高野博之、小室一成
- Journal Title
  
  循環器
  
  Pages: 136-143
- Data Source
  KAKENHI-PROJECT-19590851
[Journal Article] 造血性サイトカイン(G-CSF)による心筋梗塞治療Medical View Point2008
- Author(s)
  高野博之
- Journal Title
  
  29
  
  Pages: 5-5
- Data Source
  KAKENHI-PROJECT-19590851
[Journal Article] サイトカインによる急性心筋梗塞治療は有用か?2008
- Author(s)
  高野博之
- Journal Title
  
  専門医のための薬物療法Q & A循環器 166
- Data Source
  KAKENHI-PROJECT-19590851
[Journal Article] 急性心筋梗塞に対するG-CSF治療ICUとCCU2008
- Author(s)
  高野博之
- Journal Title
  
  31
  
  Pages: 823-832
- Data Source
  KAKENHI-PROJECT-19590851
[Journal Article] Feasibility and safety of granulocyte colony-stimulating factor treatment in patients with acute myocardial infarction2007
- Author(s)
  Takano H, Hasegawa H, Kuwabara Y, Nakayama T, Matsuno K, Miyazaki Y, Yamamoto M, Fujimoto Y, Okada H, Okubo S, Fujita M, Shindo S, Kobayashi Y, Komiyama N, Takekoshi N, Imai K, Himi T, Ishibashi I, Komuro I
- Journal Title
  
  Int. J. Cardiol. 122
  
  Pages: 41-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590851
[Journal Article] G-CSF therapy for acute myocardial infarction2007
- Author(s)
  Takano H, Ueda K, Hasegawa H, Komuro I
- Journal Title
  
  Trends Pharmacol Sci. 28
  
  Pages: 512-7
- NAID
  40015774386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590851
[Journal Article] G-CSF therapy for acute myocardial infarction2007
- Author(s)
  Takano H
- Journal Title
  
  Trends Pharmacol Sci 28
  
  Pages: 512-517
- NAID
  40015774386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590851
[Journal Article] Effects of G-CSF on left ventricular remodeling and heart failure after acute myocardial infarction2006
- Author(s)
  Takano H
- Journal Title
  
  J Mol Med 84
  
  Pages: 185-193
- Data Source
  KAKENHI-PROJECT-16659193
[Journal Article] The role of PPARgamma-dependent pathway in the development of cardiac hypertrophy2005
- Author(s)
  Takano H
- Journal Title
  
  Timely Top Med Cardiovasc Dis 9
- Data Source
  KAKENHI-PROJECT-16659193
[Journal Article] G-CSF prevents cardiac Remodeling after myocardial infarction by activating Jak/Stat in cardiomyocytes.2005
- Author(s)
  Harada, M., Qin, Y., Takano, H., Minamino, T., Zou, Y., Toko, H., Ohtsuka, M., Matsuura, K., Sano, M., Nishi, J., Akazawa, H., Kunieda, T., Zhu, W., Hasegawa, H., Kunisada, K., Nagai, T., Nakaya, H., Yamauchi-Takihara, K., Komuro, I.
- Journal Title
  
  Nat Med 11
  
  Pages: 305-311
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209025
[Journal Article] A novel LIM protein Cal promotes cardiac differentiation by association with CSX/NKX2-5.2004
- Author(s)
  Akazawa, H., Kudoh, S., Mochizuki, N., Takekoshi, N., Takano, H., Nagai, T., Komuro, I.
- Journal Title
  
  J Cell Biol 164
  
  Pages: 395-405
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209025
[Presentation] 中枢性免疫寛容を抑制する胸腺オートファジー誘導機構の解析2024
- Author(s)
  高倉勇気, 秋山伸子, 高野博之, 秋山泰身, 山口憲孝
- Organizer
  第144回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] 中枢性免疫寛容を抑制する胸腺オートファジー誘導因子の解析2024
- Author(s)
  高倉勇気、秋山伸子、高野博之、秋山泰身、山口憲孝
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] Anti-fibrotic signaling pathway of GLP-1 in heart failure2023
- Author(s)
  Hirose A, Yamaguchi N, Takano H, Kobayashi Y
- Organizer
  第87回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] ミトコンドリアタンパク質C15ORF48によるMitophagyの抑制2023
- Author(s)
  河村星香, 高倉勇気, 勝見優香, 高野博之, 山口憲孝
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] 駆出率の維持された心不全（HFpEF）モデルに対する加齢と性別による反応の相違2023
- Author(s)
  金恵理、原田紀歩、工藤藤美、高野博之、真鍋一郎
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] 胸腺上皮細胞の恒常的なオートファジー誘導因子の同定2023
- Author(s)
  高倉勇気、秋山伸子、高野博之、秋山泰身、山口憲孝
- Organizer
  日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] 中枢性免疫寛容を制御する胸腺オートファジー誘導機構の解析2023
- Author(s)
  山口憲孝、高野博之
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] 新規NF-κB標的遺伝子による飢餓非依存的オートファジーの誘導メカニズムと機能解明2023
- Author(s)
  高倉勇気, 高野博之, 山口憲孝
- Organizer
  第143回日本薬学会年会 (札幌, 2023.3.27）
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] 転写共役因子VGLL3によるPGC-1α発現を介した筋線維型変化の解析2023
- Author(s)
  大石まい, 高倉勇気, 高野博之, 山口憲孝
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] 新規NF-κB標的遺伝子による飢餓非依存的オートファジーの誘導メカニズムと機能解明2023
- Author(s)
  高倉勇気、高野博之、山口憲孝
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] 自然免疫系の刺激によるヒト表皮がん細胞のIL-1α選択的分泌機構2023
- Author(s)
  杉浦結衣, 野溝航太, 椚山瞭, 田中汐里, 高野博之, 山口憲孝
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] Stress-independent autophagy driven by a mitochondrial small protein in thymus regulates self-tolerance2023
- Author(s)
  Yuki Takakura，Moeka Machida，Natsumi Terada，Yuka Katsumi，Hiroyuki Takano，Nobuko Akiyama，Taishin Akiyama，Noritaka Yamaguchi
- Organizer
  The 9th Global Network Forum on Infection and Immunity（Chiba, 2023.2.10）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] LPA刺激による脂肪細胞分化への影響の解析2023
- Author(s)
  吉田卓眞, 南須原杏律, 高倉勇気, 石川千夏, 高野博之, 山口憲孝
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] 胸腺上皮細胞の恒常的なオートファジー誘導因子の同定2023
- Author(s)
  高倉勇気, 秋山伸子, 高野博之, 秋山泰身, 山口憲孝
- Organizer
  2023年度日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] 中枢性免疫寛容を制御する胸腺オートファジー誘導機構の解析2023
- Author(s)
  山口憲孝, 高野博之
- Organizer
  第97回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] VGLL3による細胞死非依存的なIL-1α分泌を介した炎症誘導2022
- Author(s)
  堀直人, 高倉勇気, 町田萌香, 寺田菜摘, 野溝航太, 椚山瞭, 高野博之, 山口憲孝
- Organizer
  第142回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] 転写因子 Tead の調節分子による遅筋と速筋の分化制御2022
- Author(s)
  堀直人，鈴木孝行，荒木拓郎，石川千夏，南須原杏律，高野博之，山口憲孝
- Organizer
  2022年度日本生化学会関東支部例会（千葉, 2022.6.18）
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] NF-κB依存的オートファジー誘導因子による細胞増殖2022
- Author(s)
  高倉勇気、高野博之、山口憲孝
- Organizer
  2022年度日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] Different responses to the two-hit model of HFpEF by age and gender2022
- Author(s)
  Kim H、Kudo F、Takano H、Manabe I
- Organizer
  Keystone Symposia Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] Aging engances tissue remodeling-associated gene expression in macrophages2022
- Author(s)
  Hagiwara K、Ishii T、Takano H、Manabe I
- Organizer
  Cold Spring Harbor Laboratory Meeting & Courses Program
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] 転写因子Teadの調節分子Vgll3による遅筋誘導2022
- Author(s)
  堀直人、鈴木孝行、荒木拓郎、石川千夏、南須原杏律、高野博之、山口憲孝
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] 老化に伴うマクロファージにおける組織リモデリング関連遺伝子発現の活性化を司る転写因子ネットワークの機能解析2022
- Author(s)
  萩原健太、石井貴浩、高野博之、真鍋一郎
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] Identification of a transcription factor network in macrophages in tissue remodeling2022
- Author(s)
  Hagiwara K、Ishii T、Takano H、Manabe I
- Organizer
  Cold Spring Harbor Laboratory Meeting & Courses Program
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] Hippo経路キナーゼLats1/2阻害はTead調節分子を活性化して遅筋と速筋を増加させる2022
- Author(s)
  堀直人，鈴木孝行，荒木拓郎，石川千夏，南須原杏律，高野博之，山口憲孝
- Organizer
  第96回日本薬理学会年会（横浜, 2022.11.30-12.3）
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] Vgll3とTazは協調的に遅筋と速筋の分化を制御する2022
- Author(s)
  堀直人，鈴木孝行，荒木拓郎，石川千夏，南須原杏律，高野博之，山口憲孝
- Organizer
  第66回日本薬学会関東支部大会（横浜, 2022.9.17）
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] Depressive stress induces heart failure through hematoimmune system2022
- Author(s)
  金里恵、高橋陸、原田紀歩、工藤藤美、高野博之、真鍋一郎
- Organizer
  第6回日本循環器学会基礎研究フォーラム (BCVR)
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] Protective effect of GLP-1 on cardiac fibrosis in heart failure2022
- Author(s)
  Hirose M, Yamaguchi N, Kobayashi Y, Takano H
- Organizer
  第39回国際心臓研究会(ISHR) 日本部会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] 転写因子Teadの調節分子による遅筋と速筋の分化制御2022
- Author(s)
  堀直人、鈴木孝行、荒木拓郎、石川千夏、南須原杏律、高野博之、山口憲孝
- Organizer
  2022年度日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] 転写因子Teadの調節分子Vgll3による遅筋誘導2022
- Author(s)
  堀直人，鈴木孝行，荒木拓郎，石川千夏，南須原杏律，高野博之，山口憲孝
- Organizer
  第95回日本生化学会大会（名古屋, 2022.11.9-11）
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] 自己免疫疾患関連因子VGLL3によるNF-κB経路活性化2021
- Author(s)
  堀直人, 高倉勇気, 町田萌香, 寺田菜摘, 野溝航太, 椚山瞭, 高野博之, 山口憲孝
- Organizer
  第94回日本生化学大会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] 老化はマクロファージのTLR応答を変容させる2021
- Author(s)
  萩原健太、高野博之、真鍋一郎
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] 脂肪細胞分化におけるVgll3の機能解明2021
- Author(s)
  石川千夏, 荒木拓郎, 高野博之, 山口憲孝
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] 上皮間葉転換を介したVGLL3のがん悪性化メカニズムに対する寄与2021
- Author(s)
  野溝航太、杉野歩美、平田健介、高倉勇気、堀直人、町田萌香、山口直人、高野博之、山口憲孝
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K08026
[Presentation] 転写共役因子VGLL3による炎症反応経路活性化機構の解析2021
- Author(s)
  堀直人, 高倉勇気, 町田萌香, 寺田菜摘, 椚山暸, 高野博之, 山口憲孝
- Organizer
  2021年度日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] 自己免疫疾患関連因子VGLL3によるNF-κB経路活性化2021
- Author(s)
  堀直人、高倉勇気、町田萌香、寺田菜摘、野溝航太、椚山瞭、高野博之、山口憲孝
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] 心不全におけるDPP-4阻害薬の心臓線維化抑制メカニズムに関する探索2021
- Author(s)
  廣瀬雅教、山口憲孝、小林欣夫、高野博之
- Organizer
  第69回日本心臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] 転写共役因子Vgll3による筋分化制御機構の解析2021
- Author(s)
  堀直人、鈴木孝行、荒木拓郎、高野博之、山口直人、山口憲孝
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18K08026
[Presentation] 加齢・性差に伴う心機能の評価2021
- Author(s)
  金恵理、高野博之、真鍋一郎
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] がん細胞によるマクロファージの機能制御2021
- Author(s)
  田上優月、高野博之、真鍋一郎
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K08121
[Presentation] 変異Rasによるミトコンドリア電子伝達系複合体IVタンパク質を介した細胞増殖亢進機構の解析2021
- Author(s)
  川島志織, 高倉勇気, 町田萌香, 堀直人, 荒木拓郎, 寺田菜摘, 高野博之, 山口憲孝
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] 自己免疫疾患関連因子VGLL3による炎症誘導機構の解析2021
- Author(s)
  堀直人, 高倉勇気, 町田萌香, 寺田菜摘, 野溝航太, 椚山瞭, 高野博之, 山口憲孝
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] がん細胞におけるIL-1αの機能解析2021
- Author(s)
  椚山瞭ダニエル, 堀直人, 高野博之, 山口憲孝
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] 転写共役因子Vgll3による筋分化制御機構2021
- Author(s)
  荒木拓郎, 鈴木孝行, 堀直人,石川千夏, 高野博之, 山口憲孝
- Organizer
  2021年度日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] NF-kB経路を介したオートファジー活性化機構の解析2021
- Author(s)
  寺田菜摘, 高倉勇気, 町田萌香, 堀直人, 荒木拓郎, 川村友博, 川島志織, 山口直人, 高野博之, 山口憲孝
- Organizer
  2021年度日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] NF-κB経路活性化によるオートファジー制御機構の解析2021
- Author(s)
  寺田菜摘, 高倉勇気, 町田萌香, 堀直人, 荒木拓郎, 川村友博, 川島志織, 高野博之, 山口憲孝
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06543
[Presentation] Mechanism of action of DPP-4 inhibition for cardiac fibrosis2019
- Author(s)
  Hirose Masanori, Takano Hiroyuki, Yamaguchi Noritaka, Kobayashi Yoshio
- Organizer
  日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08026
[Presentation] シンポジウム59 「心不全の地域包括ケアにおける情報共有～多職種で有用な情報共有とは～　139「心不全の地域包括ケアで求められる薬剤師の役割」2019
- Author(s)
  高野博之
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08393
[Presentation] Prognostic significance of myocardial DPP-4 expression level in patients with heart failure2018
- Author(s)
  Hirose M, Hasegawa H, Kobara Y, Yamaguchi N, Takano H, Kobayashi Y.
- Organizer
  European Society of Cardiology 2018
- Data Source
  KAKENHI-PROJECT-18K08026
[Presentation] シンポジウム45　心不全のチーム医療・在宅医療で求められる薬剤師の活躍　「心不全のチーム医療・在宅医療について」2017
- Author(s)
  高野博之
- Organizer
  第27回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-16K08393
[Presentation] 心不全の在宅医療を実践できる薬剤師の育成－千葉大学の取り組み－2017
- Author(s)
  高野　博之
- Organizer
  日本薬学会第137年会　仙台
- Place of Presentation
  東北大学川内キャンパス（宮城県仙台市）
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-16K08393
[Presentation] G-CSF therapy for acute myocardial infarction : From animal experiments to clinical trials.2008
- Author(s)
  Hiroyuki Takano, Issei Komuro
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590851
[Presentation] Myocardial Protection Strategy after Reperfusion Therapy in Acute Coronary Syndrome Cytokine therapy for myocardial infarction-G-CSF and erythropoietin-2008
- Author(s)
  Hiroshi Hasegawa, Hiroyuki Takano, Kazutaka Ueda, Raita Uchiyama, Issei Komuro
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590851
[Presentation] Erythropoietin promotes angiogenesis and prevents heart failure after myocardial infarction2008
- Author(s)
  Raita Uchiyama, Hiroyuki Takano, Kazutaka Ueda, Yuriko Niitsuma, Hiroshi Hasegawa, Issei Komuro
- Organizer
  International Conference of Geriatric Emergency & Critical Care(Keystone, CO)
- Place of Presentation
  Taipei
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-19590851
[Presentation] G-CSF Therapy for Acute Myocardial Infarction:From Animal Experiments to Chnical Trials2008
- Author(s)
  高野博之
- Organizer
  第72回日本循環器学会総会
- Place of Presentation
  福岡
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19590851
[Presentation] Erythropoietin prevents cardiac remodeling after myocardial infarction through erythropoietin receptor-induced signaling pathways in cardiomyocytes2008
- Author(s)
  Kazutaka Ueda, Hiroyuki Takano, Yuriko Niitsuma, Hiroshi Hasegawa, Raita Uchiyama, Issei Komuro
- Organizer
  International Conference of Geriatric Emergency & Critical Care(Keystone, CO)
- Place of Presentation
  Taipei
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-19590851
[Presentation] Erythropoietin prevents cardiac remodeling after myocardial infarction through erythropoietin receptor-induced signaling pathways in cardiomyocytes
- Author(s)
  Kazutaka Ueda, Hiroyuki Takano, Yuriko Niitsuma, Hiroshi Hasegawa, Raita Uchiyama, Issei Komuro
- Organizer
  2007 Annual Symposium of the American Heart Association scientific sessions
- Place of Presentation
  Orlando, FL
- Data Source
  KAKENHI-PROJECT-19590851

1. KOMURO Issei (30260483)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
2. Yamaguchi Noritaka (80399469)

# of Collaborated Projects: 4 results

# of Collaborated Products: 39 results
3. 眞鍋一郎 (70359628)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
4. MINAMINO Tohru (90328063)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. NAGAI Toshio (00334194)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. HASEGAWA Hiroshi (50375656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. YOSHIDA Katsuya (10191579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Sekine Yuko (30567350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Hashimoto Naoko (10724875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 田中知明 (50447299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 秋山伸子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takano Hiroyuki 高野 博之

TAKANO HIROYUKI 高野 博之

TAKANO Hiroyuki 高野 博之

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骨格筋の線維タイプに着目した新たな心不全治療戦略の開発Principal Investigator

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Pathophysiology and therapies of HFpEFPrincipal Investigator

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Exploratory research on novel cardioprotective agentsPrincipal Investigator

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ROLES OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR γ IN CARDIOVASCULAR DISEASEPrincipal Investigator

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[Journal Article] Mitochondrial protein C15ORF48 is a stress-independent inducer of autophagy that regulates oxidative stress and autoimmunity2024

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[Journal Article] VGLL3 confers slow-twitch muscle differentiation via PGC-1α expression in C2C12 myocytes2023

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Takano Hiroyuki 高野博之

TAKANO HIROYUKI 高野博之

TAKANO Hiroyuki 高野博之